Detailed information for compound 2072861

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 427.336 | Formula: C18H27BrN4O3
  • H donors: 0 H acceptors: 4 LogP: 1.82 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N1CCCCCC1)C1OCCN(C1)C(=O)c1cnc(nc1C)C.Br
  • InChi: 1S/C18H26N4O3.BrH/c1-13-15(11-19-14(2)20-13)17(23)22-9-10-25-16(12-22)18(24)21-7-5-3-4-6-8-21;/h11,16H,3-10,12H2,1-2H3;1H
  • InChiKey: DUIYUXDQRKMGFL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Mycobacterium ulcerans integral membrane transport protein 0.0012 0.0004 0.3608
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Echinococcus granulosus sugar phosphate exchanger 0.0012 0.0004 0.0002
Trypanosoma brucei unspecified product 0.0014 0.0006 0.0008
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0018 0.0015
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0024 0.0024
Toxoplasma gondii hypothetical protein 0.0029 0.0018 0.4297
Echinococcus multilocularis monocarboxylate transporter 0.0012 0.0004 0.0002
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0011 0.0011
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0012 0.0004 0.1002
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0012 0.0004 0.0002
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Brugia malayi probable sodium-dependent inorganic phosphate cotransporter 0.0012 0.0004 0.0004
Schistosoma mansoni adenylate cyclase 0.0012 0.0004 0.0004
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0012 0.0004 0.1002
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0013 0.0013
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0007 0.1725
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0011 0.2673
Echinococcus granulosus dna polymerase eta 0.0021 0.0011 0.0009
Onchocerca volvulus Vesicular acetylcholine transporter homolog 1.2657 1 1
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Schistosoma mansoni oxalate:formate antiporter 0.0012 0.0004 0.0004
Mycobacterium ulcerans integral membrane transport protein 0.0012 0.0004 0.3608
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0011 0.0008
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0011 0.0328
Brugia malayi transporter 0.0012 0.0004 0.0004
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0588
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0012 0.0004 0.0002
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0011 0.4999
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0011 0.0014
Echinococcus granulosus vesicular glutamate transporter 0.0012 0.0004 0.0002
Echinococcus multilocularis monocarboxylate transporter 0.0012 0.0004 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Mycobacterium ulcerans integral membrane efflux protein EfpA 0.0012 0.0004 0.3608
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0018 0.0018
Trypanosoma brucei major facilitator superfamily, putative 0.0012 0.0004 0.0005
Echinococcus granulosus bloom syndrome protein 0.0023 0.0013 0.0011
Echinococcus multilocularis transfer RNA-Leu 0.0012 0.0004 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0011 0.9853
Mycobacterium ulcerans integral membrane nitrite extrusion protein NarU 0.0012 0.0004 0.3608
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0024 0.0024
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0018 0.4297
Echinococcus granulosus dna polymerase kappa 0.0021 0.0011 0.0009
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0012 0.0004 0.0004
Echinococcus granulosus Solute carrier family 22 5 0.0012 0.0004 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0024 0.0024
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0012 0.0004 0.0002
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Echinococcus multilocularis solute carrier family 43 0.0012 0.0004 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Trypanosoma brucei transporter, putative 0.0012 0.0004 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0011 0.0014
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0005 0.0006
Trypanosoma brucei trypanothione reductase 0.0058 0.0041 0.0051
Schistosoma mansoni oxalate:formate antiporter 0.0012 0.0004 0.0004
Schistosoma mansoni sodium-dependent amino acid transporter 0.0029 0.0018 0.0018
Echinococcus granulosus monocarboxylate transporter 0.0012 0.0004 0.0002
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0029 0.0018 1
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0011 0.0304
Mycobacterium ulcerans multidrug resistance integral membrane efflux protein 0.0012 0.0004 0.3608
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0011 0.0014
Echinococcus granulosus serotonin transporter 0.0168 0.0128 0.0126
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0018 0.0018
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Leishmania major trypanothione reductase 0.0058 0.0041 0.0051
Giardia lamblia Sugar transport family protein 0.0012 0.0004 0.3608
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0002 0.0588
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0012 0.0004 0.1002
Echinococcus granulosus oxalate:formate antiporter 0.0012 0.0004 0.0002
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0018 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0004
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0006 0.0008
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0132 0.0099 0.891
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Loa Loa (eye worm) solute carrier family 6 member 4 0.0168 0.0128 0.0128
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0006 0.0008
Giardia lamblia Hypothetical protein 0.0012 0.0004 0.3608
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0018 0.0018
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0132 0.0099 0.891
Loa Loa (eye worm) hypothetical protein 0.0168 0.0128 0.0128
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Mycobacterium ulcerans drug efflux membrane protein 0.0012 0.0004 0.3608
Trypanosoma cruzi integral membrane transport protein, putative 0.0012 0.0004 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0024 0.5853
Echinococcus multilocularis vesicular glutamate transporter 0.0012 0.0004 0.0002
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Plasmodium falciparum glutathione reductase 0.002 0.0011 0.2649
Schistosoma mansoni ap endonuclease 0.002 0.0011 0.0011
Trypanosoma cruzi protein associated with differentiation 8, putative 0.0012 0.0004 0.0005
Mycobacterium ulcerans hypothetical protein 0.0012 0.0004 0.3608
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0011 0.0009
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0018 0.0018
Trypanosoma cruzi transporter, putative 0.0012 0.0004 0.0005
Mycobacterium tuberculosis Probable oxidoreductase 0.0147 0.0111 1
Echinococcus granulosus geminin 0.039 0.0303 0.0301
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0029 0.0018 0.0018
Toxoplasma gondii hypothetical protein 0.0012 0.0004 0.1002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Echinococcus multilocularis monocarboxylate transporter 0.0012 0.0004 0.0002
Plasmodium vivax transporter, putative 0.0012 0.0004 0.1002
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Brugia malayi glutathione reductase 0.0058 0.0041 0.0041
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0011 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0006 0.0008
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Echinococcus multilocularis Glycerol 3 phosphate transporter 0.0012 0.0004 0.0002
Onchocerca volvulus 0.029 0.0225 0.0221
Brugia malayi Pre-SET motif family protein 0.0255 0.0197 0.0197
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0011 0.0011
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0029 0.0018 0.0015
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0011 0.9422
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0012 0.0004 0.1002
Plasmodium falciparum metabolite/drug transporter, putative 0.0012 0.0004 0.1002
Echinococcus granulosus sugar phosphate exchanger 3 0.0012 0.0004 0.0002
Echinococcus granulosus Hippocampus abundant transcript 1 protein 0.0012 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trypanosoma brucei major facilitator superfamily, putative 0.0012 0.0004 0.0005
Leishmania major monocarboxylate transporter-like protein 0.0012 0.0004 0.0005
Mycobacterium ulcerans integral membrane transport protein 0.0012 0.0004 0.3608
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Plasmodium falciparum transporter, putative 0.0029 0.0018 0.4297
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) thioredoxin reductase 0.0058 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0004
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0029 0.0018 0.0015
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0005 0.0006
Trypanosoma cruzi trypanothione reductase, putative 0.0058 0.0041 0.0051
Schistosoma mansoni ap endonuclease 0.002 0.0011 0.0011
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Echinococcus granulosus oxalate:formate antiporter 0.0012 0.0004 0.0002
Trypanosoma brucei riboflavin transporter 0.0012 0.0004 0.0005
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0168 0.0128 0.0128
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0011 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0012 0.0004 0.0002
Leishmania major DNA polymerase eta, putative 0.0021 0.0011 0.0014
Leishmania major C-8 sterol isomerase-like protein 1.0105 0.7983 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0024 0.0021
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0011 0.0309
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.039 0.0303 0.0303
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0011 0.0014
Schistosoma mansoni drug transporter 0.0012 0.0004 0.0004
Schistosoma mansoni sugar transporter 0.0012 0.0004 0.0004
Echinococcus granulosus oxalate:formate antiporter 0.0012 0.0004 0.0002
Giardia lamblia hypothetical protein 0.0012 0.0004 0.3608
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Echinococcus granulosus monocarboxylate transporter 0.0012 0.0004 0.0002
Echinococcus granulosus synaptic vesicular amine transporter 0.0012 0.0004 0.0002
Plasmodium vivax glutathione reductase, putative 0.0058 0.0041 1
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Plasmodium falciparum glutathione reductase 0.0058 0.0041 1
Loa Loa (eye worm) norepinephrine transporter 0.0168 0.0128 0.0128
Mycobacterium ulcerans transmembrane protein 0.0012 0.0004 0.3608
Schistosoma mansoni phosphate transporter 0.0012 0.0004 0.0004
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0013 0.0011
Trypanosoma brucei protein associated with differentiation 6, putative 0.0012 0.0004 0.0005
Mycobacterium ulcerans integral membrane transport protein 0.0012 0.0004 0.3608
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0018 0.0018
Plasmodium vivax sugar transporter, putative 0.0012 0.0004 0.1002
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Brugia malayi Abnormal catecholamine distribution protein 1 0.0012 0.0004 0.0004
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0018 0.0018
Toxoplasma gondii hypothetical protein 0.0029 0.0018 0.4297
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Trypanosoma cruzi protein associated with differentiation 4, putative 0.0012 0.0004 0.0005
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Echinococcus granulosus oxalate:formate antiporter 0.0012 0.0004 0.0002
Trypanosoma brucei Protein Associated with Differentiation 0.0012 0.0004 0.0005
Schistosoma mansoni transport proetin (smap-4-related) 0.0012 0.0004 0.0004
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0018 0.0015
Plasmodium falciparum monocarboxylate transporter, putative 0.0012 0.0004 0.1002
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0011 0.0011
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 1.0105 0.7983 0.7983
Echinococcus multilocularis MFS transporter ceroid lipofuscinosis neuronal 0.0012 0.0004 0.0002
Giardia lamblia Hypothetical protein 0.0012 0.0004 0.3608
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0011 0.963
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0011 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Plasmodium vivax thioredoxin reductase, putative 0.0058 0.0041 1
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0004
Toxoplasma gondii zinc finger protein 36 family 3 protein 0.0012 0.0004 0.1002
Trypanosoma cruzi integral membrane transport protein, putative 0.0012 0.0004 0.0005
Echinococcus multilocularis serotonin transporter 0.0168 0.0128 0.0126
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0011 0.0014
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0012 0.0004 0.0004
Trypanosoma brucei protein associated with differentiation 4, putative 0.0012 0.0004 0.0005
Giardia lamblia MDR-type permease 0.0012 0.0004 0.3608
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0018 0.0015
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0012 0.0004 0.0002
Loa Loa (eye worm) serotonin transporter b 0.0168 0.0128 0.0128
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Brugia malayi transporter 0.0012 0.0004 0.0004
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0011 0.2661
Schistosoma mansoni feline leukemia virus subgroup C receptor-related 0.0012 0.0004 0.0004
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Schistosoma mansoni vesicular acetylcholine transporter 1.2657 1 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0024 0.0021
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Echinococcus multilocularis synaptic vesicular amine transporter 0.0012 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Mycobacterium ulcerans MFS transporter 0.0012 0.0004 0.3608
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0012 0.0004 0.0002
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Echinococcus granulosus protein spinster 0.0012 0.0004 0.0002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0011 0.0675
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0011 0.0014
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0018 0.0018
Echinococcus granulosus Glycerol 3 phosphate transporter 0.0012 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trypanosoma brucei Protein Associated with Differentiation, putative 0.0012 0.0004 0.0005
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0011 1
Echinococcus granulosus feline leukemia virus subgroup C 0.0012 0.0004 0.0002
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0007 0.176
Trypanosoma brucei transporter, putative 0.0012 0.0004 0.0005
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0011 0.0011
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0012 0.0004 0.0004
Schistosoma mansoni sodium-dependent phosphate transporter 0.0012 0.0004 0.0004
Plasmodium falciparum pantothenate transporter 0.0012 0.0004 0.1002
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0012 0.0004 0.0002
Trypanosoma brucei major facilitator superfamily, putative 0.0012 0.0004 0.0005
Echinococcus granulosus oxalate:formate antiporter 0.0012 0.0004 0.0002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0011 0.0008
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0011 0.9542
Giardia lamblia Multidrug resistance protein B 0.0012 0.0004 0.3608
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0011 0.0309
Brugia malayi Pre-SET motif family protein 0.0037 0.0024 0.0024
Trypanosoma cruzi major facilitator superfamily, putative 0.0012 0.0004 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Schistosoma mansoni DNA polymerase eta 0.0021 0.0011 0.0011
Trypanosoma brucei Protein Associated with Differentiation 1 0.0012 0.0004 0.0005
Echinococcus multilocularis survival motor neuron protein 1 0.0254 0.0196 0.0194
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Echinococcus multilocularis sugar phosphate exchanger solute carrier family 0.0012 0.0004 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0011 0.0014
Schistosoma mansoni vesicular amine transporter 0.0012 0.0004 0.0004
Trypanosoma cruzi hypothetical protein 0.0012 0.0004 0.0005
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0018 0.0015
Schistosoma mansoni drug efflux protein-related 0.0012 0.0004 0.0004
Leishmania major transporter, putative,major facilitator superfamily protein (MFS), putative 0.0012 0.0004 0.0005
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0012 0.0004 0.0002
Treponema pallidum sodium- and chloride- dependent transporter 0.0168 0.0128 1
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0012 0.0004 0.0002
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0011 0.2649
Mycobacterium ulcerans hypothetical protein 0.0012 0.0004 0.3608
Brugia malayi ERG2 and Sigma1 receptor like protein 1.0105 0.7983 0.7983
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0011 0.0304
Echinococcus multilocularis feline leukemia virus subgroup C 0.0012 0.0004 0.0002
Plasmodium vivax transporter, putative 0.0012 0.0004 0.1002
Trypanosoma brucei C-8 sterol isomerase, putative 1.0105 0.7983 1
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus MFS transporter ceroid lipofuscinosis neuronal 0.0012 0.0004 0.0002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Plasmodium falciparum thioredoxin reductase 0.0058 0.0041 1
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0168 0.0128 0.0128
Trypanosoma brucei major facilitator superfamily, putative 0.0012 0.0004 0.0005
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Loa Loa (eye worm) hypothetical protein 0.5165 0.4078 0.4078
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0012 0.0004 0.0004
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0011 0.0014
Mycobacterium ulcerans integral membrane drug efflux protein 0.0012 0.0004 0.3608
Mycobacterium ulcerans hypothetical protein 0.0012 0.0004 0.3608
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Trypanosoma brucei unspecified product 0.0021 0.0011 0.0014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0023 0.002
Plasmodium vivax metabolite/drug transporter, putative 0.0012 0.0004 0.1002
Trypanosoma cruzi transporter, putative 0.0012 0.0004 0.0005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0005 0.0023
Echinococcus multilocularis solute carrier family 43 0.0012 0.0004 0.0002
Echinococcus granulosus monocarboxylate transporter 0.0012 0.0004 0.0002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0018 0.0018
Trypanosoma cruzi transporter, putative 0.0012 0.0004 0.0005
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0011 0.2649
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Echinococcus multilocularis vesicular glutamate transporter 0.0012 0.0004 0.0002
Schistosoma mansoni solute carrier family 17 member 7 (vesicular glutamate transporter 0.0012 0.0004 0.0004
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0011 0.0014
Leishmania major hypothetical protein, unknown function 0.0012 0.0004 0.0005
Mycobacterium tuberculosis Probable reductase 0.0132 0.0099 0.891
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0011 0.0014
Echinococcus multilocularis vesicular acetylcholine transporter 1.2657 1 1
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Loa Loa (eye worm) hippocampus abundant transcript 1a 0.0012 0.0004 0.0004
Trypanosoma brucei major facilitator superfamily, putative 0.0012 0.0004 0.0005
Schistosoma mansoni survival motor neuron protein 0.0052 0.0036 0.0036
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0011 0.0014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0249 0.0192 0.0192
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0011 0.9542
Trypanosoma cruzi transporter, putative 0.0012 0.0004 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0147 0.0111 1
Loa Loa (eye worm) hypothetical protein 0.0254 0.0196 0.0196
Echinococcus multilocularis synaptic vesicle 2 protein 0.0012 0.0004 0.0002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0011 0.9542
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0255 0.0197 0.0197
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Loa Loa (eye worm) RecQ helicase 0.0023 0.0013 0.0013
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0011 0.9853
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0011 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0024 0.0021
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Trypanosoma cruzi major facilitator superfamily, putative 0.0012 0.0004 0.0005
Leishmania major hypothetical protein, conserved in leishmania 0.0012 0.0004 0.0005
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0012 0.0004 0.0002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0132 0.0099 0.891
Echinococcus granulosus synaptic vesicle 2 protein 0.0012 0.0004 0.0002
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0004
Mycobacterium ulcerans integral membrane protein 0.0012 0.0004 0.3608
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0011 0.0014
Schistosoma mansoni oxalate:formate antiporter 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0011 1
Schistosoma mansoni phosphate transporter 0.0012 0.0004 0.0004
Schistosoma mansoni feline leukemia virus subgroup C receptor-related 0.0012 0.0004 0.0004
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0018 0.0015
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0036 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Giardia lamblia Hypothetical protein 0.0012 0.0004 0.3608
Plasmodium falciparum monocarboxylate transporter, putative 0.0012 0.0004 0.1002
Echinococcus granulosus monocarboxylate transporter 0.0012 0.0004 0.0002
Echinococcus granulosus vesicular acetylcholine transporter 1.2657 1 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Echinococcus multilocularis synaptic vesicle 2 protein 0.0012 0.0004 0.0002
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0011 0.0011
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Schistosoma mansoni oxalate:formate antiporter 0.0012 0.0004 0.0004
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0011 0.0014
Echinococcus multilocularis monocarboxylate transporter 0.0012 0.0004 0.0002
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Echinococcus granulosus synaptic vesicle 2 protein 0.0012 0.0004 0.0002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0018 0.4297
Mycobacterium ulcerans integral membrane transport protein 0.0012 0.0004 0.3608
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0168 0.0128 0.0128
Onchocerca volvulus 0.0052 0.0036 0.0032
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Echinococcus multilocularis monocarboxylate transporter 0.0012 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Onchocerca volvulus 0.0029 0.0018 0.0013
Mycobacterium ulcerans integral membrane protein 0.0012 0.0004 0.3608
Giardia lamblia Hypothetical protein 0.0012 0.0004 0.3608
Plasmodium vivax pantothenate transporter, putative 0.0012 0.0004 0.1002
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0011 0.0011
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0011 0.2649
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0013 0.0407
Trichomonas vaginalis set domain proteins, putative 0.029 0.0225 1
Plasmodium falciparum thioredoxin reductase 0.002 0.0011 0.2649
Leishmania major hypothetical protein, unknown function 0.0012 0.0004 0.0005
Toxoplasma gondii thioredoxin reductase 0.0058 0.0041 1
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0002 0.2118
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0011 0.2649
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0011 0.2649
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0012 0.0004 0.3608
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Brugia malayi follicle stimulating hormone receptor 0.0249 0.0192 0.0192
Plasmodium falciparum amino acid transporter, putative 0.0029 0.0018 0.4297
Echinococcus granulosus solute carrier family 43 0.0012 0.0004 0.0002
Schistosoma mansoni sodium/sialic acid cotransporter 0.0012 0.0004 0.0004
Mycobacterium ulcerans transmembrane carbohydrate transport protein 0.0012 0.0004 0.3608
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0147 0.0111 1
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0011 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0147 0.0111 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0011 0.0014
Trypanosoma cruzi drug resistance protein, putative 0.0012 0.0004 0.0005
Trypanosoma brucei transporter, putative 0.0012 0.0004 0.0005
Mycobacterium ulcerans transmembrane transport protein 0.0012 0.0004 0.3608
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Leishmania major integral membrane transport protein, putative,drug resistence protein, putative 0.0012 0.0004 0.0005
Echinococcus granulosus vesicular glutamate transporter 0.0012 0.0004 0.0002
Onchocerca volvulus 0.0037 0.0024 0.002
Echinococcus granulosus sodium dependent phosphate transport protein 1 0.0012 0.0004 0.0002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Schistosoma mansoni oxalate:formate antiporter 0.0012 0.0004 0.0004
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus monocarboxylate transporter 0.0012 0.0004 0.0002
Echinococcus granulosus thioredoxin glutathione reductase 0.0058 0.0041 0.0038
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0011 0.963
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0588
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0011 0.9542
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0011 0.0014
Echinococcus multilocularis Hippocampus abundant transcript 1 protein 0.0012 0.0004 0.0002
Echinococcus multilocularis dna polymerase eta 0.0021 0.0011 0.0009
Mycobacterium ulcerans nitrite extrusion protein, NarK3_3 0.0012 0.0004 0.3608
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0018 0.0018
Trypanosoma brucei protein associated with differentiation 5, putative 0.0012 0.0004 0.0005
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0005 0.0715
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0013 0.0407
Schistosoma mansoni protein transport protein Sec13 0.0012 0.0004 0.0004
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0011 0.0009
Echinococcus granulosus oxalate:formate antiporter 0.0012 0.0004 0.0002
Echinococcus granulosus survival motor neuron protein 1 0.0254 0.0196 0.0194
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0029 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Toxoplasma gondii hypothetical protein 0.0012 0.0004 0.1002
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0012 0.0004 0.1002
Echinococcus granulosus monocarboxylate transporter 0.0012 0.0004 0.0002
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0012 0.0004 0.1002
Echinococcus granulosus oxalate:formate antiporter 0.0012 0.0004 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Onchocerca volvulus 0.0029 0.0018 0.0013
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Plasmodium vivax amine transporter, putative 0.0029 0.0018 0.4297
Toxoplasma gondii exonuclease III APE 0.002 0.0011 0.2673
Echinococcus multilocularis geminin 0.039 0.0303 0.0301
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0011 0.0011
Giardia lamblia TM efflux prot 0.0012 0.0004 0.3608
Schistosoma mansoni hypothetical protein 0.0052 0.0036 0.0036
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0011 0.2649
Toxoplasma gondii hypothetical protein 0.0012 0.0004 0.1002
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0029 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Giardia lamblia Multidrug resistance protein B 0.0012 0.0004 0.3608
Echinococcus granulosus oxalate:formate antiporter 0.0012 0.0004 0.0002
Brugia malayi Hypothetical transporter C09D4.1 0.0012 0.0004 0.0004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0018 0.4297
Plasmodium vivax monocarboxylate transporter, putative 0.0012 0.0004 0.1002
Mycobacterium tuberculosis Probable dehydrogenase 0.0132 0.0099 0.891
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Schistosoma mansoni drug efflux protein-related 0.0012 0.0004 0.0004
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 1.2657 1 1
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0018 0.0018
Trypanosoma cruzi major facilitator superfamily, putative 0.0012 0.0004 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0011 0.0014
Echinococcus granulosus solute carrier family 43 0.0012 0.0004 0.0002
Echinococcus multilocularis monocarboxylate transporter 0.0012 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0132 0.0099 0.891
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0011 0.0636
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0018 0.4297
Trypanosoma cruzi protein associated with differentiation 8, putative 0.0012 0.0004 0.0005
Trypanosoma brucei protein associated with differentiation 3, putative 0.0012 0.0004 0.0005
Mycobacterium ulcerans integral membrane transport protein 0.0012 0.0004 0.3608
Schistosoma mansoni transporter spinster-related 0.0012 0.0004 0.0004
Mycobacterium ulcerans intergral membrane protein 0.0012 0.0004 0.3608
Plasmodium vivax transporter, putative 0.0012 0.0004 0.1002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0011 0.0009
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0011 0.0011
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Plasmodium vivax transporter, putative 0.0012 0.0004 0.1002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Mycobacterium ulcerans aminoglycosides/tetracycline-transport integral membrane protein 0.0012 0.0004 0.3608
Leishmania major MFS transporter, putative 0.0012 0.0004 0.0005
Trypanosoma cruzi transporter, putative 0.0012 0.0004 0.0005
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0011 0.0014
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Schistosoma mansoni sialin (solute carrier family 17 member 5) (sodium/sialic acid cotransporter) (ast) (membrane glycoprotein hp59) 0.0012 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Echinococcus multilocularis sodium dependent phosphate transport protein 1 0.0012 0.0004 0.0002
Trypanosoma brucei protein associated with differentiation 7, putative 0.0012 0.0004 0.0005
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Echinococcus multilocularis MFS transporter ceroid lipofuscinosis neuronal 0.0012 0.0004 0.0002
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0012 0.0004 0.1002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0011 0.2673
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Echinococcus multilocularis thioredoxin glutathione reductase 0.0058 0.0041 0.0038
Leishmania major DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0009 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0024 0.0024
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0007 0.0007
Schistosoma mansoni selectively expressed in embryonic epithelia protein-1 0.0012 0.0004 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0011 0.0014
Mycobacterium ulcerans integral membrane nitrite extrusion protein NarK3 0.0012 0.0004 0.3608
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0012 0.0004 0.0002
Leishmania major transporter-like protein 0.0012 0.0004 0.0005
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0018 0.0018
Giardia lamblia DINP protein human, muc B family 0.0021 0.0011 1
Trypanosoma cruzi MFS transporter, putative 0.0012 0.0004 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0011 0.0008
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0018 0.0018
Echinococcus granulosus monocarboxylate transporter 0.0012 0.0004 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Trypanosoma brucei transporter protein, putative 0.0012 0.0004 0.0005
Trypanosoma brucei major facilitator superfamily protein (MFS), putative 0.0012 0.0004 0.0005
Echinococcus multilocularis monocarboxylate transporter 0.0012 0.0004 0.0002
Trypanosoma brucei unspecified product 0.0014 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus multilocularis sugar phosphate exchanger 3 0.0012 0.0004 0.0002
Schistosoma mansoni tetracycline-efflux transporter 0.0012 0.0004 0.0004
Plasmodium vivax transporter, putative 0.0012 0.0004 0.1002
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0011 0.0328
Echinococcus multilocularis oxalate:formate antiporter 0.0012 0.0004 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0012 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0168 0.0128 0.0128
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0011 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0011 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0011 0.0014
Echinococcus granulosus MFS transporter ceroid lipofuscinosis neuronal 0.0012 0.0004 0.0002
Schistosoma mansoni vesicular amine transporter 0.0012 0.0004 0.0004
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0005 0.0006
Schistosoma mansoni DNA helicase recq1 0.0009 0.0002 0.0002
Plasmodium vivax SET domain protein, putative 0.0037 0.0024 0.5853
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Brugia malayi hypothetical protein 0.0029 0.0018 0.0018
Echinococcus multilocularis protein spinster 0.0012 0.0004 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0011 0.0014
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.039 0.0303 0.0303
Mycobacterium ulcerans integral membrane protein 0.0012 0.0004 0.3608
Giardia lamblia Major facilitator family transporter 0.0012 0.0004 0.3608
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0012 0.0004 0.0002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0012 0.0004 0.0004
Onchocerca volvulus 0.0029 0.0018 0.0013
Toxoplasma gondii transporter, major facilitator family protein 0.0012 0.0004 0.1002
Schistosoma mansoni sodium/chloride dependent transporter 0.0168 0.0128 0.0128
Trypanosoma brucei protein associated with differentiation 8, putative 0.0012 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trypanosoma brucei drug resistence protein, putative 0.0012 0.0004 0.0005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0132 0.0099 0.891
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Schistosoma mansoni monocarboxylate transporter 0.0012 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0029 0.0018 0.0015
Schistosoma mansoni sugar transporter 0.0012 0.0004 0.0004
Trypanosoma cruzi C-8 sterol isomerase, putative 1.0105 0.7983 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Brugia malayi Thioredoxin reductase 0.0058 0.0041 0.0041
Onchocerca volvulus 0.0168 0.0128 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0011 0.0675
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0012 0.0004 0.0002
Brugia malayi hypothetical protein 0.0254 0.0196 0.0196
Echinococcus granulosus oxalate:formate antiporter 0.0012 0.0004 0.0002
Trypanosoma cruzi major facilitator superfamily, putative 0.0012 0.0004 0.0005
Plasmodium vivax transporter, putative 0.0012 0.0004 0.1002
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0011 0.0627
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Trypanosoma cruzi transporter, putative 0.0012 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus monocarboxylate transporter 0.0012 0.0004 0.0002
Giardia lamblia Hypothetical protein 0.0012 0.0004 0.3608
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0012 0.0004 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0011 0.0014
Schistosoma mansoni DNA helicase recq5 0.0009 0.0002 0.0002
Trypanosoma cruzi hypothetical protein 0.0012 0.0004 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0011 0.0014
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0058 0.0041 0.3425
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0005
Leishmania major hypothetical protein, conserved 0.0012 0.0004 0.0005
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0012 0.0004 0.0005
Loa Loa (eye worm) glutathione reductase 0.0058 0.0041 0.0041

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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