Detailed information for compound 2076136

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 444.408 | Formula: C18H23F3N6O4
  • H donors: 2 H acceptors: 5 LogP: -1.72 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1cnc(nc1)N1CCOC2(C1)COCCN(C2)Cc1cc[nH]n1.OC(=O)C(F)(F)F
  • InChi: 1S/C16H22N6O2.C2HF3O2/c1-3-17-15(18-4-1)22-7-9-24-16(12-22)11-21(6-8-23-13-16)10-14-2-5-19-20-14;3-2(4,5)1(6)7/h1-5H,6-13H2,(H,19,20);(H,6,7)
  • InChiKey: BQKUOGSCYLMLHH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis protein kinase c iota type 0.0047 0.0067 0.0067
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0033 0.0033 0.2108
Echinococcus granulosus protein kinase c epsilon type 0.012 0.0246 0.0447
Echinococcus granulosus raf serine:threonine protein kinase 0.0019 0.0001 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0074 0.0133 0.0133
Schistosoma mansoni DNA ligase IV 0.0021 0.0005 0.0008
Echinococcus multilocularis tar DNA binding protein 0.0234 0.052 0.052
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Brugia malayi AMP-binding enzyme family protein 0.0066 0.0113 0.0384
Echinococcus multilocularis neuropeptide receptor 0.0086 0.0162 0.0162
Echinococcus multilocularis ecdysone induced protein 78C 0.0074 0.0133 0.0133
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0032 0.1202
Toxoplasma gondii AGC kinase 0.0027 0.002 0.0741
Schistosoma mansoni cellular tumor antigen P53 0.0046 0.0065 0.0118
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0078 0.0078
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0019 0.0001 0.0000076815
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0246 0.0446
Brugia malayi ecdysteroid receptor 0.0074 0.0133 0.0451
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0272 0.0612 0.208
Brugia malayi Nuclear hormone receptor-like 1 0.0074 0.0133 0.0451
Echinococcus multilocularis carbonic anhydrase II 0.0272 0.0612 0.0612
Echinococcus granulosus importin subunit beta 1 0.0046 0.0066 0.012
Schistosoma mansoni hypothetical protein 0.0123 0.0253 0.0459
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0035 0.0038 0.0038
Loa Loa (eye worm) jmjC domain-containing protein 0.0124 0.0254 0.0864
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0034 0.0036 0.0122
Plasmodium vivax importin-beta 2, putative 0.0046 0.0066 0.2544
Brugia malayi TAR-binding protein 0.0234 0.052 0.1768
Toxoplasma gondii HEAT repeat-containing protein 0.0046 0.0066 0.2485
Schistosoma mansoni hypothetical protein 0.04 0.0922 0.1677
Schistosoma mansoni protein kinase C mu 0.0019 0.0001 0.0000076815
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.002 0.0002 0.0006
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0005 0.016
Echinococcus granulosus polycomb protein SCMH1 0.0076 0.0139 0.0253
Onchocerca volvulus Bile acid receptor homolog 0.0074 0.0133 0.0565
Schistosoma mansoni hypothetical protein 0.0035 0.0038 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0242 0.7235
Brugia malayi mbt repeat family protein 0.0076 0.0139 0.0471
Brugia malayi hypothetical protein 0.0209 0.0461 0.1566
Leishmania major DNA polymerase eta, putative 0.003 0.0026 0.0406
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0005 0.0018
Loa Loa (eye worm) steroid hormone receptor 0.0074 0.0133 0.0452
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0035 0.0038 0.0038
Trichomonas vaginalis ap endonuclease, putative 0.0033 0.0033 0.014
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0005 0.0018
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0307 0.0698 0.1271
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.0113 0.1957
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0001 0.0001
Brugia malayi RhoGEF domain containing protein 0.0019 0.0001 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0024 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0074 0.0133 0.0451
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0053 0.0083 0.1434
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0104 0.0205 0.0371
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0119 0.0243 0.0443
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0017
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0066 0.0113 0.1957
Mycobacterium tuberculosis Probable dehydrogenase 0.0075 0.0135 0.8692
Schistosoma mansoni myelin transcription factor 1 myt1 0.0087 0.0164 0.0298
Schistosoma mansoni importin beta-1 0.0046 0.0066 0.0119
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0033 0.0033 0.1275
Schistosoma mansoni jumonji/arid domain-containing protein 0.0124 0.0254 0.0461
Treponema pallidum exodeoxyribonuclease (exoA) 0.0033 0.0033 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0035 0.0038 0.0069
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0032 0.0032
Loa Loa (eye worm) MBCTL1 0.0087 0.0164 0.0559
Schistosoma mansoni carbonic anhydrase-related 0.0128 0.0263 0.0477
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0493 0.1149 0.3908
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0033 0.0033 0.0534
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0076 0.0139 0.059
Brugia malayi Protein kinase domain containing protein 0.0027 0.002 0.0067
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0026 0.0945
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0074 0.0133 0.0133
Loa Loa (eye worm) oxidoreductase 0.0019 0.0001 0.0003
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0242 0.044
Brugia malayi hypothetical protein 0.0021 0.0005 0.0015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0066 0.4262
Echinococcus granulosus GTP binding nuclear protein Ran 0.0034 0.0036 0.0066
Brugia malayi tailless protein 0.0035 0.0038 0.0129
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0049 0.0073 1
Schistosoma mansoni ap endonuclease 0.0033 0.0033 0.0059
Schistosoma mansoni diacylglycerol kinase theta 0.0019 0.0001 0.0000076815
Loa Loa (eye worm) hypothetical protein 0.008 0.0147 0.0501
Loa Loa (eye worm) hypothetical protein 0.0062 0.0105 0.0358
Loa Loa (eye worm) hypothetical protein 0.0074 0.0133 0.0452
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0023 0.0009 0.0016
Entamoeba histolytica acyl-coA synthetase, putative 0.0066 0.0113 0.3375
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0001
Schistosoma mansoni atypical protein kinase C 0.0047 0.0067 0.0121
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.0113 0.1957
Brugia malayi Pre-SET motif family protein 0.0125 0.0257 0.0873
Loa Loa (eye worm) hypothetical protein 0.0071 0.0125 0.0425
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0033 0.0033 0.0534
Schistosoma mansoni topbp1 0.0021 0.0005 0.0008
Trichomonas vaginalis set domain proteins, putative 0.0985 0.234 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.0039 0.0039
Giardia lamblia PHD finger protein 15 0.0051 0.0076 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0019 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0383 0.0881 0.1602
Onchocerca volvulus 0.0023 0.0009 0.0033
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0032 0.011
Plasmodium vivax thioredoxin reductase, putative 0.0033 0.0033 0.1269
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0113 0.0228 0.0776
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0242 0.0822
Brugia malayi Steroid receptor seven-up type 2 0.0074 0.0133 0.0451
Echinococcus granulosus protein kinase c iota type 0.0047 0.0067 0.0122
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0038 0.0069
Echinococcus granulosus peregrin 0.0051 0.0076 0.0139
Brugia malayi Protein kinase domain containing protein 0.0027 0.002 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.002 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0257 0.0466
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0019 0.0001 0.0000076815
Loa Loa (eye worm) hypothetical protein 0.0049 0.0073 0.0248
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0017
Echinococcus granulosus serine:threonine protein kinase N2 0.0071 0.0126 0.023
Entamoeba histolytica hypothetical protein 0.0157 0.0334 1
Echinococcus multilocularis GPCR, family 2 0.009 0.0171 0.0171
Schistosoma mansoni hypothetical protein 0.0157 0.0334 0.0607
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0005 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0032 0.011
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0049 0.0073 0.4684
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0053 0.0083 0.0151
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0078 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0074 0.0133 0.0451
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0021 0.0005 0.0272
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0032 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Mycobacterium ulcerans hypothetical protein 0.0066 0.0113 0.1957
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0019 0.0001 0.0001
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0019 0.0001 0.0003
Toxoplasma gondii PHD-finger domain-containing protein 0.0051 0.0076 0.2884
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0032 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0033 0.0033 0.1245
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0074 0.0133 0.0452
Echinococcus multilocularis polycomb protein SCMH1 0.0076 0.0139 0.0139
Schistosoma mansoni steroid hormone receptor ad4bp 0.0074 0.0133 0.0241
Schistosoma mansoni hypothetical protein 0.0049 0.0073 0.0132
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0087 0.0164 0.0299
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0033 0.0033 0.0534
Loa Loa (eye worm) hypothetical protein 0.0071 0.0125 0.0425
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0033 0.0033 0.0061
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0034 0.0036 0.139
Entamoeba histolytica PH domain containing protein kinase, putative 0.0071 0.0126 0.377
Echinococcus granulosus Protein kinase C brain isozyme 0.011 0.0221 0.0403
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0074 0.0133 0.0241
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0076 0.2952
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0128 0.0263 0.0894
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.009 0.0171 0.0312
Loa Loa (eye worm) hypothetical protein 0.0039 0.0049 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0018
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.002 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0114 0.0229 0.0781
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0114 0.0231 0.0783
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0018
Plasmodium vivax acyl-CoA synthetase, putative 0.0049 0.0073 0.2821
Loa Loa (eye worm) hypothetical protein 0.0339 0.0775 0.2637
Plasmodium vivax glutathione reductase, putative 0.0033 0.0033 0.1269
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0073 0.1257
Loa Loa (eye worm) hypothetical protein 0.0076 0.0139 0.0472
Loa Loa (eye worm) CXXC zinc finger family protein 0.0047 0.0067 0.0228
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0066 0.0113 0.1957
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0078 0.0328
Loa Loa (eye worm) hypothetical protein 0.0039 0.0049 0.0165
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0019 0.0001 0.0001
Echinococcus multilocularis cpg binding protein 0.0049 0.0073 0.0073
Brugia malayi mbt repeat family protein 0.0076 0.0139 0.0471
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.009 0.0171 0.0312
Brugia malayi sulfakinin receptor protein 0.0114 0.0229 0.0779
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0074 0.0133 0.0451
Trypanosoma brucei importin beta-1 subunit, putative 0.0046 0.0066 0.1067
Schistosoma mansoni hypothetical protein 0.009 0.0171 0.0311
Onchocerca volvulus Protein ultraspiracle homolog 0.0074 0.0133 0.0565
Brugia malayi hypothetical protein 0.005 0.0075 0.0252
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0074 0.0133 0.0242
Leishmania major 4-coumarate:coa ligase-like protein 0.0066 0.0113 0.1842
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.002 0.0035
Loa Loa (eye worm) glutathione reductase 0.0033 0.0033 0.0113
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Brugia malayi C1-like domain containing protein 0.002 0.0002 0.0006
Brugia malayi nuclear receptor NHR-88 0.0074 0.0133 0.0451
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0056 0.0188
Loa Loa (eye worm) carbonic anhydrase 3 0.0272 0.0612 0.2081
Echinococcus multilocularis SAM and MBT domain containing protein 0.0076 0.0139 0.0139
Entamoeba histolytica Ran family GTPase 0.0034 0.0036 0.1068
Brugia malayi Fli-1 protein 0.0195 0.0425 0.1445
Loa Loa (eye worm) hypothetical protein 0.0074 0.0133 0.0452
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0049 0.0164
Onchocerca volvulus Huntingtin homolog 0.0077 0.014 0.0594
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0074 0.0133 0.0452
Brugia malayi steroid hormone receptor 0.0074 0.0133 0.0451
Onchocerca volvulus 0.0021 0.0005 0.0018
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0051 0.0076 0.0138
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0053 0.0083 0.1349
Brugia malayi hypothetical protein 0.0157 0.0334 0.1135
Echinococcus multilocularis tumor protein p63 0.0314 0.0715 0.0715
Plasmodium falciparum glutathione reductase 0.0033 0.0033 0.124
Loa Loa (eye worm) hypothetical protein 0.0077 0.0141 0.0479
Schistosoma mansoni carbonic anhydrase-related 0.0128 0.0263 0.0477
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0125 0.0257 0.0257
Echinococcus multilocularis raf serine:threonine protein kinase 0.0019 0.0001 0.0001
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0074 0.0133 0.0241
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0039 0.0049 0.0087
Brugia malayi Cytochrome P450 family protein 0.0029 0.0024 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Toxoplasma gondii hypothetical protein 0.0128 0.0263 1
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0078 0.0141
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0272 0.0612 0.1112
Echinococcus granulosus muscleblind protein 0.0339 0.0775 0.1411
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0226 0.05 0.091
Echinococcus multilocularis serine:threonine protein kinase N2 0.0027 0.002 0.002
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Loa Loa (eye worm) hypothetical protein 0.0051 0.0078 0.0264
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0066 0.4262
Brugia malayi F/Y-rich N-terminus family protein 0.0035 0.004 0.0133
Echinococcus multilocularis snurportin 1 0.0493 0.1149 0.1149
Echinococcus multilocularis GA binding protein alpha chain 0.0064 0.0109 0.0109
Echinococcus granulosus GA binding protein alpha chain 0.0064 0.0109 0.0199
Toxoplasma gondii thioredoxin reductase 0.0033 0.0033 0.124
Echinococcus multilocularis serine:threonine protein kinase 38 0.0027 0.002 0.002
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0074 0.0133 0.0451
Loa Loa (eye worm) jmjC domain-containing protein 0.0104 0.0207 0.0703
Echinococcus multilocularis serine threonine protein kinase 0.0091 0.0175 0.0175
Echinococcus multilocularis PHD finger protein rhinoceros 0.0051 0.0076 0.0076
Entamoeba histolytica protein kinase, putative 0.0027 0.002 0.0583
Loa Loa (eye worm) AGC/AKT protein kinase 0.0027 0.002 0.0069
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0053 0.0083 0.0083
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0027 0.002 0.002
Echinococcus granulosus protein kinase c eta type 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0221 0.0401
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0157 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.009 0.0172 0.0584
Loa Loa (eye worm) hypothetical protein 0.0046 0.0065 0.0222
Loa Loa (eye worm) nuclear receptor NHR-67 0.0035 0.0038 0.0131
Echinococcus granulosus nuclear receptor nhr 48 0.0035 0.0038 0.007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0113 0.0228 0.0228
Brugia malayi RhoGAP domain containing protein 0.0019 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0066 0.0113 0.0384
Echinococcus granulosus snurportin 1 0.0493 0.1149 0.209
Loa Loa (eye worm) hypothetical protein 0.0039 0.0049 0.0165
Echinococcus granulosus protein kinase C gamma type 0.0091 0.0175 0.0318
Schistosoma mansoni cpg binding protein 0.0047 0.0067 0.0121
Brugia malayi jmjC domain containing protein 0.0032 0.0032 0.0108
Schistosoma mansoni sex comb on midleg homolog 0.0076 0.0139 0.0251
Brugia malayi Protein kinase domain containing protein 0.0027 0.002 0.0067
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0141 0.5337
Echinococcus multilocularis G protein coupled receptor 139 0.0086 0.0162 0.0162
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0073 0.0131 0.0238
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0017
Schistosoma mansoni transcription factor LCR-F1 0.0157 0.0334 0.0607
Echinococcus granulosus SAM and MBT domain containing protein 0.0076 0.0139 0.0253
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0039 0.0049 0.0088
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0123 0.0253 0.046
Schistosoma mansoni tar DNA-binding protein 0.0234 0.052 0.0945
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0033 0.0033 1
Loa Loa (eye worm) PHD-finger family protein 0.0051 0.0076 0.026
Loa Loa (eye worm) CAMK/PKD protein kinase 0.002 0.0002 0.0008
Echinococcus multilocularis N chimaerin 0.0019 0.0001 0.0001
Leishmania major DNA polymerase eta, putative 0.0042 0.0056 0.0901
Brugia malayi hypothetical protein 0.0077 0.0141 0.0477
Leishmania major importin beta-1 subunit, putative 0.0037 0.0045 0.072
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0049 0.0164
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0005 0.0073
Echinococcus granulosus Rac GTPase activating protein 1 0.0019 0.0001 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0038 0.007
Echinococcus granulosus expressed conserved protein 0.0112 0.0224 0.0408
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0038 0.0069
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0035 0.0038 0.0161
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0125 0.0257 0.0466
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0074 0.0133 0.0451
Echinococcus multilocularis importin subunit beta 1 0.0046 0.0066 0.0066
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0074 0.0133 0.0242
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.002 0.0035
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0005 0.0164
Toxoplasma gondii diacylglycerol kinase, putative 0.0019 0.0001 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0284 0.0641 0.2182
Brugia malayi latrophilin 2 splice variant baaae 0.0194 0.0424 0.1441
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0027 0.002 0.002
Schistosoma mansoni nuclear receptor nhr-48 0.0035 0.0038 0.0069
Loa Loa (eye worm) hypothetical protein 0.0071 0.0125 0.0425
Schistosoma mansoni hypothetical protein 0.0019 0.0001 0.0000076815
Schistosoma mansoni carbonic anhydrase-related 0.0128 0.0263 0.0477
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0074 0.0133 0.0241
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0032 0.0057
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.011
Brugia malayi nuclear hormone receptor 0.0074 0.0133 0.0451
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.009 0.0171 0.0582
Entamoeba histolytica acyl-CoA synthetase, putative 0.0066 0.0113 0.3375
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0039 0.0049 0.0049
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0033 0.0033 0.2116
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Leishmania major trypanothione reductase 0.0033 0.0033 0.0532
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.009 0.0171 0.0171
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0141 0.5337
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0075 0.0135 0.8692
Schistosoma mansoni topbp1 0.0021 0.0005 0.0008
Brugia malayi jmjC domain containing protein 0.0124 0.0254 0.0863
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0037 0.0045 0.0188
Echinococcus multilocularis carbonic anhydrase 0.0128 0.0263 0.0263
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0075 0.0135 0.8692
Onchocerca volvulus 0.0125 0.0257 0.1095
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0002 0.0003
Echinococcus granulosus neuropeptide receptor 0.0086 0.0162 0.0294
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0033 0.0033 0.0568
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0034 0.0036 0.0583
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0032 0.1202
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0005 0.016
Schistosoma mansoni patched 1 0.0051 0.0078 0.014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0038 0.0038
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0125 0.0257 0.0257
Onchocerca volvulus Alhambra homolog 0.0051 0.0076 0.0323
Echinococcus granulosus carbonic anhydrase 0.0128 0.0263 0.0478
Echinococcus granulosus GPCR family 2 0.009 0.0171 0.0312
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0272 0.0612 0.208
Echinococcus multilocularis thioredoxin glutathione reductase 0.0033 0.0033 0.0033
Mycobacterium tuberculosis Probable oxidoreductase 0.0083 0.0155 1
Onchocerca volvulus 0.0114 0.0231 0.0983
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.0056 0.0901
Echinococcus granulosus N chimaerin 0.0019 0.0001 0.0001
Onchocerca volvulus 0.0046 0.0065 0.0276
Echinococcus multilocularis dna polymerase eta 0.0042 0.0056 0.0056
Toxoplasma gondii PHD-finger domain-containing protein 0.0051 0.0076 0.2884
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0073 0.0131 0.0131
Echinococcus granulosus dna polymerase eta 0.0042 0.0056 0.0102
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0083 0.0282
Entamoeba histolytica hypothetical protein 0.0157 0.0334 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0087 0.0164 0.0558
Echinococcus granulosus unc 13 munc13 0.0023 0.0009 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0234 0.052 0.0945
Onchocerca volvulus 0.0985 0.234 1
Echinococcus multilocularis protein kinase c eta type 0.0019 0.0001 0.0001
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0073 0.0131 0.4984
Loa Loa (eye worm) hypothetical protein 0.0049 0.0073 0.0248
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.012 0.0246 0.0836
Loa Loa (eye worm) DR-78 0.0035 0.0038 0.0131
Brugia malayi hypothetical protein 0.0021 0.0005 0.0015
Brugia malayi hypothetical protein 0.0035 0.0038 0.0129
Brugia malayi exodeoxyribonuclease III family protein 0.0033 0.0033 0.0112
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.002 0.0002 0.0008
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0032 0.0032
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0005 0.0015
Echinococcus multilocularis FTZ F1 alpha 0.0074 0.0133 0.0133
Echinococcus granulosus histone acetyltransferase MYST2 0.0087 0.0164 0.0299
Schistosoma mansoni microtubule-associated protein tau 0.2288 0.5495 1
Brugia malayi Muscleblind-like protein 0.0339 0.0775 0.2636
Loa Loa (eye worm) glutaminase 2 0.0257 0.0576 0.1958
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0074 0.0133 0.0451
Echinococcus granulosus tumor protein p63 0.0314 0.0715 0.1301
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0074 0.0133 0.0242
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0272 0.0612 0.2081
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0141 0.229
Loa Loa (eye worm) hypothetical protein 0.0074 0.0133 0.0452
Loa Loa (eye worm) transcription factor SMAD2 0.0083 0.0154 0.0524
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0066 0.0113 0.1957
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0074 0.0133 0.0242
Echinococcus granulosus myotubularin protein 13 0.0019 0.0001 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0033 0.0033 0.014
Brugia malayi PHD-finger family protein 0.0051 0.0076 0.0258
Schistosoma mansoni jumonji domain containing protein 0.0192 0.0418 0.0759
Schistosoma mansoni hypothetical protein 0.0049 0.0073 0.0132
Entamoeba histolytica hypothetical protein 0.0157 0.0334 1
Brugia malayi Nuclear hormone receptor E75 0.0035 0.0038 0.0129
Brugia malayi hypothetical protein 0.0039 0.0049 0.0164
Loa Loa (eye worm) hypothetical protein 0.0042 0.0056 0.019
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Brugia malayi nuclear receptor NHR-88 0.0035 0.0038 0.0129
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0034 0.0036 0.0583
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0005 0.0069
Brugia malayi hypothetical protein 0.0114 0.0229 0.0779
Loa Loa (eye worm) glutaminase 0.0257 0.0576 0.1958
Brugia malayi glutathione reductase 0.0033 0.0033 0.0112
Loa Loa (eye worm) AGC/PKN protein kinase 0.0027 0.002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0257 0.0466
Schistosoma mansoni unc-13 (munc13) 0.0023 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0049 0.0073 0.0248
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0074 0.0133 0.0451
Entamoeba histolytica diacylglycerol kinase, putative 0.0019 0.0001 0.0001
Brugia malayi conserved hypotetical protein 0.0035 0.0038 0.0129
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0032 0.0059
Schistosoma mansoni jumonji/arid domain-containing protein 0.0124 0.0254 0.0461
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0126
Brugia malayi RNA, U transporter 1 0.0131 0.0272 0.0925
Plasmodium falciparum carbonic anhydrase 0.0128 0.0263 1
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0005 0.0069
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0032 0.0516
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0064 0.011 0.0373
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0027 0.002 0.0069
Leishmania major carbonic anhydrase-like protein 0.0272 0.0612 1
Trichomonas vaginalis glutaminase, putative 0.0257 0.0576 0.2457
Schistosoma mansoni hypothetical protein 0.009 0.0171 0.0311
Echinococcus multilocularis nuclear receptor nhr 48 0.0035 0.0038 0.0038
Echinococcus granulosus ecdysone induced protein 78C 0.0074 0.0133 0.0242
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0113 0.0228 0.0414
Brugia malayi jmjC domain containing protein 0.0032 0.0032 0.0108
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0032 0.0516
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0023 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.1233 0.2939 0.5349
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Loa Loa (eye worm) hypothetical protein 0.0066 0.0113 0.0385
Schistosoma mansoni nuclear receptor 0.0035 0.0038 0.0069
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0074 0.0133 0.0241
Brugia malayi nuclear hormone receptor family member odr-7 0.0035 0.0038 0.0129
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.0365 0.0365
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0141 0.229
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.0039 0.007
Loa Loa (eye worm) hypothetical protein 0.0051 0.0076 0.026
Echinococcus multilocularis myotubularin protein 13 0.0019 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.009 0.0171 0.0311
Loa Loa (eye worm) latrophilin receptor protein 2 0.009 0.0171 0.0583
Brugia malayi jmjC domain containing protein 0.0032 0.0032 0.0108
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0027 0.002 0.0037
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0027 0.002 0.0037
Echinococcus granulosus Diacylglycerol kinase theta 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0074 0.0133 0.0452
Brugia malayi RNA recognition motif domain containing protein 0.0234 0.052 0.1768
Brugia malayi Ets-domain containing protein 0.0064 0.0109 0.037
Schistosoma mansoni survival motor neuron protein 0.0114 0.0231 0.0418
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0087 0.0164 0.0164
Plasmodium falciparum phd finger protein, putative 0.0051 0.0076 0.2884
Trypanosoma brucei DNA polymerase eta, putative 0.0042 0.0056 0.0901
Schistosoma mansoni hypothetical protein 0.0194 0.0424 0.077
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0246 0.0447
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0033 0.0033 0.0534
Loa Loa (eye worm) hypothetical protein 0.0077 0.014 0.0475
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0005 0.0126
Entamoeba histolytica hypothetical protein 0.0019 0.0001 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0073 0.0131 0.4984
Entamoeba histolytica hypothetical protein 0.0037 0.0045 0.132
Loa Loa (eye worm) hypothetical protein 0.009 0.0171 0.0583
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0039 0.0049 0.0165
Onchocerca volvulus 0.0023 0.0009 0.0037
Plasmodium falciparum acyl-CoA synthetase 0.0049 0.0073 0.2756
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0034 0.0036 0.0583
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0032 0.011
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0272 0.0612 0.1112
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0018
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0064 0.0109 0.0371
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0075 0.0135 0.8692
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0033 0.0033 0.3983
Loa Loa (eye worm) hypothetical protein 0.0339 0.0775 0.2637
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0035 0.0038 0.0038
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0032 0.0516
Echinococcus multilocularis protein kinase c epsilon type 0.012 0.0246 0.0246
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0032 0.1202
Echinococcus multilocularis protein patched 0.0051 0.0078 0.0078
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0035 0.0038 0.0069
Schistosoma mansoni retinoic acid receptor RXR 0.0074 0.0133 0.0241
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0032 0.0059
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0074 0.0133 0.0565
Echinococcus granulosus nibrin 0.0021 0.0005 0.0009
Loa Loa (eye worm) TAR-binding protein 0.0234 0.052 0.1769
Echinococcus granulosus dnaJ subfamily B 0.0383 0.0881 0.1603
Echinococcus granulosus survival motor neuron protein 1 0.056 0.131 0.2384
Schistosoma mansoni unc-13 (munc13) 0.0024 0.0013 0.0023
Echinococcus multilocularis histone acetyltransferase MYST2 0.0087 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Brugia malayi ecdysone receptor 0.0035 0.0038 0.0129
Schistosoma mansoni diacylglycerol kinase theta 0.0019 0.0001 0.0000076815
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0038 0.0038
Entamoeba histolytica diacylglycerol kinase, putative 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0017
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0027 0.002 0.002
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0033 0.0532
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0019 0.0001 0.0005
Onchocerca volvulus 0.0047 0.0067 0.0283
Brugia malayi nuclear receptor RXR 0.0035 0.0038 0.0129
Loa Loa (eye worm) hypothetical protein 0.0074 0.0133 0.0452
Entamoeba histolytica acyl-CoA synthetase, putative 0.0066 0.0113 0.3375
Loa Loa (eye worm) hypothetical protein 0.0066 0.0113 0.0385
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0032 0.0032
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0033 0.0059
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0027 0.002 0.0069
Echinococcus multilocularis geminin 0.04 0.0922 0.0922
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0113 0.0228 0.0415
Schistosoma mansoni tar DNA-binding protein 0.0234 0.052 0.0945
Loa Loa (eye worm) hypothetical protein 0.0046 0.0066 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0074 0.0133 0.0451
Echinococcus granulosus carbonic anhydrase 0.0128 0.0263 0.0478
Schistosoma mansoni hypothetical protein 0.047 0.1093 0.1989
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0074 0.0133 0.0452
Entamoeba histolytica hypothetical protein 0.0157 0.0334 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0101 0.0342
Echinococcus granulosus Nuclear hormone receptor HR96 0.0035 0.0038 0.007
Brugia malayi glutaminase DH11.1 0.0257 0.0576 0.1957
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.0113 0.1957
Toxoplasma gondii exonuclease III APE 0.0033 0.0033 0.1245
Loa Loa (eye worm) hypothetical protein 0.0049 0.0073 0.0248
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.011
Schistosoma mansoni glutaminase 0.0257 0.0576 0.1046
Onchocerca volvulus 0.0066 0.0113 0.0481
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0128 0.0263 0.0893
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0074 0.0133 0.0451
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.005 0.0074 0.0253
Echinococcus granulosus NDR protein kinase 0.0027 0.002 0.0037
Echinococcus granulosus cpg binding protein 0.0049 0.0073 0.0134
Echinococcus multilocularis muscleblind protein 1 0.0339 0.0775 0.0775
Entamoeba histolytica protein kinase, putative 0.0027 0.002 0.0583
Brugia malayi nuclear receptor NHR-67 0.0035 0.0038 0.0129
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0017
Trypanosoma brucei importin beta-1 subunit, putative 0.0046 0.0066 0.1067
Brugia malayi MH2 domain containing protein 0.0083 0.0154 0.0523
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.1233 0.2939 0.2939
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0049 0.0087
Loa Loa (eye worm) thioredoxin reductase 0.0033 0.0033 0.0113
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.1233 0.2939 0.5349
Plasmodium vivax SET domain protein, putative 0.0125 0.0257 1
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0005 0.0069
Leishmania major 4-coumarate:coa ligase-like protein 0.0066 0.0113 0.1842
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0027 0.002 0.0069
Schistosoma mansoni hypothetical protein 0.0051 0.0076 0.0138
Brugia malayi nuclear hormone receptor 0.0035 0.0038 0.0129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0113 0.0228 0.0414
Brugia malayi hypothetical protein 0.0035 0.0038 0.0129
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0053 0.0083 0.015
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0242 0.0242
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0074 0.0133 0.0452
Brugia malayi orphan nuclear receptor NR2E1 0.0035 0.0038 0.0129
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0234 0.052 0.1769
Mycobacterium ulcerans glutaminase 0.0257 0.0576 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0123 0.0253 0.0253
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0113 0.0228 0.0228
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0038 0.0069
Brugia malayi Importin beta-1 subunit 0.0046 0.0066 0.0223
Leishmania major GTP-binding protein, putative 0.0034 0.0036 0.0583
Brugia malayi Nuclear hormone receptor E75 0.0035 0.0038 0.0129
Brugia malayi diacylglycerol kinase 0.0019 0.0001 0.0001
Echinococcus granulosus lysine specific demethylase 5A 0.0124 0.0254 0.0462
Entamoeba histolytica protein kinase, putative 0.0027 0.002 0.0583
Brugia malayi Pre-SET motif family protein 0.0866 0.2051 0.6976
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.002 0.0035
Brugia malayi protein kinase C3,putative 0.002 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Loa Loa (eye worm) raf kinase 0.0019 0.0001 0.0003
Echinococcus multilocularis nibrin 0.0021 0.0005 0.0005
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0035 0.0038 0.0038
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.1233 0.2939 1
Onchocerca volvulus 0.0209 0.0461 0.1966
Schistosoma mansoni hypothetical protein 0.0049 0.0073 0.0132
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0075 0.0135 0.8692
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0035 0.0038 0.0131
Brugia malayi nuclear receptor RXR 0.0039 0.0049 0.0164
Echinococcus multilocularis unc 13 (munc13) 0.0023 0.0009 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Echinococcus granulosus PHD finger protein rhinoceros 0.0051 0.0076 0.0139
Leishmania major hypothetical protein, conserved 0.0077 0.0141 0.229
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0005 0.0005
Plasmodium falciparum thioredoxin reductase 0.0033 0.0033 0.124
Brugia malayi Ets-domain containing protein 0.0064 0.0109 0.037
Brugia malayi CXXC zinc finger family protein 0.0047 0.0067 0.0226
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0113 0.0228 0.0415
Schistosoma mansoni protein kinase C mu 0.002 0.0002 0.0003
Schistosoma mansoni thyroid hormone receptor 0.0197 0.0432 0.0784
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0005 0.0009
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0074 0.0133 0.0133
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0032 0.0057
Echinococcus multilocularis carbonic anhydrase 0.0128 0.0263 0.0263
Trypanosoma brucei trypanothione reductase 0.0033 0.0033 0.0532
Schistosoma mansoni zinc finger protein 0.0035 0.0038 0.0069
Schistosoma mansoni protein kinase C 0.0023 0.0009 0.0014
Echinococcus granulosus carbonic anhydrase 0.0128 0.0263 0.0478
Brugia malayi photoreceptor-specific nuclear receptor 0.0074 0.0133 0.0451
Loa Loa (eye worm) hypothetical protein 0.0074 0.0133 0.0452
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0032 0.0057
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.002 0.0002 0.0002
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0125 0.0257 0.0874
Brugia malayi hypothetical protein 0.0077 0.014 0.0474
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0027 0.002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0077 0.014 0.0475
Schistosoma mansoni hypothetical protein 0.0114 0.0231 0.0418
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0018
Echinococcus multilocularis serine:threonine protein kinase N2 0.0098 0.0191 0.0191
Schistosoma mansoni ran 0.0034 0.0036 0.0065
Loa Loa (eye worm) hypothetical protein 0.0103 0.0203 0.0689
Schistosoma mansoni nuclear hormone receptor 0.0074 0.0133 0.0241
Onchocerca volvulus 0.0076 0.0139 0.059
Brugia malayi diacylglycerol kinase 0.0019 0.0001 0.0001
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0128 0.0263 0.0893
Loa Loa (eye worm) hypothetical protein 0.0074 0.0133 0.0452
Brugia malayi protein kinase C II. 0.012 0.0246 0.0835
Loa Loa (eye worm) fli-1 protein 0.0195 0.0425 0.1446
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0027 0.002 0.0037
Schistosoma mansoni hypothetical protein 0.0049 0.0073 0.0132
Echinococcus multilocularis expressed conserved protein 0.0112 0.0224 0.0224
Schistosoma mansoni thyroid hormone receptor 0.0197 0.0432 0.0784
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0284 0.0641 0.2181
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0005 0.0015
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0005 0.0018
Echinococcus multilocularis carbonic anhydrase 0.0128 0.0263 0.0263
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0074 0.0133 0.0451
Brugia malayi AMP-binding enzyme family protein 0.0066 0.0113 0.0384
Brugia malayi Latrophilin receptor protein 2 0.009 0.0171 0.0582
Schistosoma mansoni tar DNA-binding protein 0.0234 0.052 0.0945
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0074 0.0133 0.0452
Echinococcus granulosus geminin 0.04 0.0922 0.1678
Echinococcus multilocularis thyroid hormone receptor alpha 0.0197 0.0432 0.0432
Schistosoma mansoni coup transcription factor 0.0074 0.0133 0.0241
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0866 0.2051 0.6977
Echinococcus granulosus jumonji domain containing protein 0.007 0.0124 0.0226
Loa Loa (eye worm) hypothetical protein 0.0066 0.0113 0.0385
Loa Loa (eye worm) RasGEF domain-containing protein 0.0019 0.0001 0.0003
Brugia malayi jmjC domain containing protein 0.0226 0.05 0.1701
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0073 0.0131 0.0239
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0307 0.0698 0.0698
Loa Loa (eye worm) hypothetical protein 0.0128 0.0263 0.0894
Echinococcus multilocularis protein dispatched 1 0.0058 0.0095 0.0095
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0125 0.0257 0.9769
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0074 0.0133 0.0451
Schistosoma mansoni neuropeptide receptor 0.0086 0.0162 0.0293
Loa Loa (eye worm) hypothetical protein 0.0284 0.0641 0.2182
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0141 0.5337
Echinococcus multilocularis Rac GTPase activating protein 1 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0074 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0098 0.0191 0.065
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0128 0.0263 0.0893
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0034 0.0036 0.1358
Loa Loa (eye worm) AGC/NDR protein kinase 0.0027 0.002 0.0069
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0113 0.0228 0.0775
Loa Loa (eye worm) hypothetical protein 0.0209 0.0461 0.1567
Schistosoma mansoni ap endonuclease 0.0033 0.0033 0.0059
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0157 0.0334 0.0608
Entamoeba histolytica protein kinase, putative 0.0027 0.002 0.0583
Schistosoma mansoni ets-related 0.0195 0.0425 0.0772
Brugia malayi hypothetical protein 0.056 0.131 0.4457
Brugia malayi indoleamine 2,3-dioxygenase 0.1233 0.2939 1
Plasmodium falciparum importin beta, putative 0.0046 0.0066 0.2485
Schistosoma mansoni vav2 0.0019 0.0001 0.0000076815
Loa Loa (eye worm) RNA binding protein 0.0234 0.052 0.1769
Loa Loa (eye worm) hypothetical protein 0.0087 0.0164 0.0559
Brugia malayi p70 ribosomal S6 kinase beta 0.0027 0.002 0.0067
Brugia malayi Pleckstrin Homology Domain 0.0019 0.0001 0.0001
Schistosoma mansoni sex comb on midleg homolog 0.0076 0.0139 0.0251
Loa Loa (eye worm) hypothetical protein 0.0119 0.0242 0.0823
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0074 0.0133 0.0452
Echinococcus multilocularis Diacylglycerol kinase theta 0.0019 0.0001 0.0001
Brugia malayi RNA binding protein 0.0234 0.052 0.1768
Brugia malayi Calcitonin receptor-like protein seb-1 0.0284 0.0641 0.2181
Schistosoma mansoni carbonic anhydrase 0.0128 0.0263 0.0477
Brugia malayi nuclear hormone receptor family member nhr-6 0.0035 0.0038 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0221 0.0401
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0113 0.7294
Schistosoma mansoni DNA polymerase eta 0.0042 0.0056 0.01
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0113 0.0228 0.0414
Loa Loa (eye worm) mbt repeat family protein 0.0076 0.0139 0.0472
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0035 0.0038 0.0129
Trypanosoma cruzi DNA polymerase eta, putative 0.003 0.0026 0.0406
Echinococcus multilocularis dnaJ subfamily B 0.0383 0.0881 0.0881
Plasmodium vivax JmjC domain containing protein 0.0032 0.0032 0.1231
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0019 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0074 0.0133 0.0451
Schistosoma mansoni RAR-like nuclear receptor 0.0074 0.0133 0.0241
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0035 0.0038 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0018
Schistosoma mansoni hypothetical protein 0.1233 0.2939 0.5349
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0083 0.0155 1
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0019 0.0001 0.0003
Schistosoma mansoni nuclear receptor 0.0035 0.0038 0.0069
Schistosoma mansoni hypothetical protein 0.009 0.0171 0.0311
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0017
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0074 0.0133 0.0133
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0141 0.5463
Brugia malayi Protein kinase c protein 2 0.0084 0.0157 0.0531
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0034 0.0036 0.0036
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0001 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0066 0.4262
Echinococcus granulosus histone lysine methyltransferase setb 0.0125 0.0257 0.0467
Trypanosoma brucei rac serine-threonine kinase, putative 0.0027 0.002 0.0318
Brugia malayi RhoGAP domain containing protein 0.0019 0.0001 0.0001
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0074 0.0133 0.0242
Echinococcus multilocularis lysine specific demethylase 5A 0.0121 0.0248 0.0248
Echinococcus multilocularis RNA directed DNA polymerase 0.0061 0.0101 0.0101
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0005 0.016
Onchocerca volvulus Huntingtin homolog 0.0077 0.014 0.0594
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0061 0.0101 0.0101
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0033 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.04 0.0922 0.1677
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0037 0.0045 0.0188
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0076 0.0139 0.0251
Brugia malayi Ras association domain family 1 isoform A 0.0019 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0128 0.0263 0.0477
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0074 0.0133 0.0242
Trichomonas vaginalis ran, putative 0.0034 0.0036 0.0152
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0032 0.0032
Leishmania major 4-coumarate:coa ligase-like protein 0.0066 0.0113 0.1842
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0272 0.0612 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0226 0.05 0.05
Loa Loa (eye worm) hypothetical protein 0.0039 0.0049 0.0165
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Brugia malayi CHE-14 protein 0.0051 0.0078 0.0262
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0027 0.0019 0.0077
Toxoplasma gondii histone lysine methyltransferase SET1 0.0093 0.0179 0.6803
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0078 0.0264
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0002 0.0003
Echinococcus granulosus microtubule associated protein 2 0.2288 0.5495 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0034 0.0036 0.1358
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0033 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0001 0.0000076815
Echinococcus granulosus thioredoxin glutathione reductase 0.0033 0.0033 0.0061
Echinococcus granulosus tar DNA binding protein 0.0234 0.052 0.0946
Echinococcus multilocularis peregrin 0.0051 0.0076 0.0076
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0053 0.0083 0.1434
Echinococcus granulosus phd:f box containing protein 0.0032 0.0032 0.0059
Schistosoma mansoni gabp alpha 0.0064 0.0109 0.0197
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0029
Trichomonas vaginalis importin beta-1, putative 0.0037 0.0045 0.0188
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0032 0.0059
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0083 0.0155 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0037 0.0045 0.072
Schistosoma mansoni cpg binding protein 0.0049 0.0073 0.0132
Echinococcus multilocularis muscleblind protein 0.0339 0.0775 0.0775
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0272 0.0612 1
Schistosoma mansoni ran 0.0034 0.0036 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0074 0.0133 0.0451
Loa Loa (eye worm) hypothetical protein 0.0194 0.0424 0.1442
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0019 0.0001 0.0003
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0128 0.0263 0.0893
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.0365 0.0665
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0257 0.0466
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Schistosoma mansoni rac gtpase activating protein 0.0019 0.0001 0.0000076815
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0066 0.0113 0.1957
Onchocerca volvulus 0.0071 0.0125 0.0531
Echinococcus granulosus FTZ F1 alpha 0.0074 0.0133 0.0242
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0074 0.0133 0.0133
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0005 0.0069
Loa Loa (eye worm) hypothetical protein 0.0055 0.0087 0.0295
Echinococcus granulosus RNA directed DNA polymerase 0.0061 0.0101 0.0183
Brugia malayi Thioredoxin reductase 0.0033 0.0033 0.0112
Brugia malayi Variant SH3 domain containing protein 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0053 0.0083 0.5343
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0033 0.0033 0.0979
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.009 0.0171 0.0171
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0083 0.0155 1
Onchocerca volvulus 0.0035 0.0038 0.0161
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0035 0.0038 0.0161
Onchocerca volvulus 0.0074 0.0133 0.0565
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Brugia malayi DKFZp564C0469 protein 0.0021 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Brugia malayi topoisomerase 0.0021 0.0005 0.0015
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0034 0.0036 0.0124
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Onchocerca volvulus 0.0035 0.0038 0.0161
Echinococcus granulosus Nuclear hormone receptor HR96 0.0035 0.0038 0.007
Echinococcus granulosus thyroid hormone receptor alpha 0.0035 0.0038 0.007
Loa Loa (eye worm) hypothetical protein 0.0074 0.0133 0.0452
Leishmania major hypothetical protein, conserved 0.0032 0.0032 0.0516
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0074 0.0133 0.0241
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0005 0.0018
Echinococcus multilocularis jumonji domain containing protein 0.007 0.0124 0.0124
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0066 0.0113 0.7294
Loa Loa (eye worm) hypothetical protein 0.0128 0.0263 0.0894
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0034 0.0036 0.4398
Loa Loa (eye worm) hypothetical protein 0.0128 0.0263 0.0894
Brugia malayi Protein kinase domain containing protein 0.002 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0131
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0066 0.4262
Loa Loa (eye worm) hypothetical protein 0.056 0.131 0.4457
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0005 0.0069
Echinococcus granulosus carbonic anhydrase II 0.0272 0.0612 0.1113
Mycobacterium tuberculosis Probable reductase 0.0075 0.0135 0.8692
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0019 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0493 0.1149 0.2089
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0128 0.0263 0.0893
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0074 0.0133 0.0241
Brugia malayi hypothetical protein 0.0039 0.0049 0.0164
Schistosoma mansoni cpg binding protein 0.0049 0.0073 0.0132
Echinococcus granulosus serine:threonine protein kinase N2 0.0027 0.002 0.0037
Loa Loa (eye worm) nuclear hormone receptor 0.0035 0.0038 0.0131
Loa Loa (eye worm) hypothetical protein 0.0074 0.0133 0.0452
Echinococcus multilocularis Protein kinase C, brain isozyme 0.011 0.0221 0.0221
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0066 0.0113 0.7294
Loa Loa (eye worm) MH2 domain-containing protein 0.0083 0.0154 0.0524
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0141 0.229
Echinococcus multilocularis survival motor neuron protein 1 0.056 0.131 0.131
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Brugia malayi Bromodomain containing protein 0.0051 0.0076 0.0258
Trichomonas vaginalis AGC family protein kinase 0.0027 0.002 0.0083
Brugia malayi Hr1 repeat family protein 0.0027 0.002 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0234 0.052 0.0945
Brugia malayi jmjC domain containing protein 0.0032 0.0032 0.0108
Loa Loa (eye worm) hypothetical protein 0.0049 0.0073 0.0248
Loa Loa (eye worm) hypothetical protein 0.0039 0.0049 0.0165
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0066 0.0113 0.7294
Trypanosoma brucei carbonic anhydrase-like protein 0.0272 0.0612 1
Schistosoma mansoni serine/threonine kinase 0.0027 0.002 0.0035
Echinococcus multilocularis microtubule associated protein 2 0.2288 0.5495 0.5495
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0075 0.0135 0.8692
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0074 0.0133 0.0242

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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