Detailed information for compound 37165

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 321.395 | Formula: C15H19N3O3S
  • H donors: 1 H acceptors: 3 LogP: 3.66 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCSc1ccc2c(c1)nc(n2C(=O)CC)NC(=O)OC
  • InChi: 1S/C15H19N3O3S/c1-4-8-22-10-6-7-12-11(9-10)16-14(17-15(20)21-3)18(12)13(19)5-2/h6-7,9H,4-5,8H2,1-3H3,(H,16,17,20)
  • InChiKey: BIEIRYTXIAGWPT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0039
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Schistosoma mansoni inositol transporter 0.0038 0.0169 0.0223
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.004 0.0178 0.0178
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0049 0.0016
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.006 0.0079
Schistosoma mansoni opsin-like receptor 0.0431 0.2585 0.3414
Loa Loa (eye worm) G-protein coupled receptor 0.0431 0.2585 0.3716
Echinococcus multilocularis neuropeptide receptor A26 0.0431 0.2585 0.2585
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0099 0.0131
Schistosoma mansoni netrin receptor unc5 0.0029 0.0113 0.0149
Loa Loa (eye worm) G-protein coupled receptor 0.0431 0.2585 0.3716
Echinococcus multilocularis rhodopsin orphan GPCR 0.0431 0.2585 0.2585
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0843 0.5115 0.7353
Echinococcus granulosus rhodopsin orphan GPCR 0.0431 0.2585 0.3414
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0139 0.0482
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0431 0.2585 0.3414
Onchocerca volvulus 0.0431 0.2585 0.8987
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0416 0.0518
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.0416 0.0549
Loa Loa (eye worm) Smad1 0.0024 0.0081 0.0117
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0049 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0164
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0099 0.0143
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0139 0.0335
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.006 0.0087
Echinococcus granulosus neuropeptide FF receptor 2 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0324 0.1928 0.2771
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0049 0.0016
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.1242 0.757 1
Brugia malayi GnHR receptor homolog 0.0431 0.2585 0.3414
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0055 0.0072
Loa Loa (eye worm) glutathione reductase 0.0048 0.0231 0.0332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0431 0.2585 0.3414
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.004 0.0178 0.0235
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0038 0.0169 0.0169
Echinococcus granulosus lamin dm0 0.0027 0.0099 0.0131
Leishmania major protein kinase A catalytic subunit 0.004 0.0178 0.0213
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0846 0.1118
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0068 0.0068
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.042 0.2518 0.3619
Echinococcus multilocularis sex peptide receptor 0.0431 0.2585 0.2585
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0068 0.0083
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Schistosoma mansoni neuropeptide receptor 0.0431 0.2585 0.3414
Leishmania major hypothetical protein, conserved 0.0016 0.0035 0.0036
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.004 0.0178 0.0213
Echinococcus granulosus neuropeptides capa receptor 0.0431 0.2585 0.3414
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0431 0.2585 0.3716
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0039
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0431 0.2585 0.3414
Loa Loa (eye worm) neuropeptide F receptor 0.0431 0.2585 0.3716
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0055 0.0072
Echinococcus multilocularis pyruvate kinase 0.0026 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0347 0.2065 0.2968
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0249 0.0329
Onchocerca volvulus 0.0431 0.2585 0.8987
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.0612 0.2452
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.1242 0.757 0.9381
Echinococcus multilocularis neuropeptide receptor 0.0431 0.2585 0.2585
Trichomonas vaginalis AGC family protein kinase 0.004 0.0178 0.0227
Schistosoma mansoni sodium/solute symporter 0.0038 0.0169 0.0223
Echinococcus multilocularis rhodopsin orphan GPCR 0.0431 0.2585 0.2585
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0139 0.0199
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0049 0.0054
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0223 0.0294
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0178 0.0235
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.004 0.0178 0.0235
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0305 0.0372
Echinococcus multilocularis lamin dm0 0.0027 0.0099 0.0099
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0039
Onchocerca volvulus 0.0431 0.2585 0.8987
Onchocerca volvulus 0.0431 0.2585 0.8987
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0399 0.239 0.2956
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0055 0.0055
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0114 0.0102
Brugia malayi phosphofructokinase 0.0108 0.06 0.0793
Loa Loa (eye worm) phosphofructokinase 0.0108 0.06 0.0863
Echinococcus multilocularis GPCR, family 2 0.0047 0.0223 0.0223
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.1242 0.757 1
Echinococcus granulosus solute carrier family 5 0.0038 0.0169 0.0223
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0305 0.0305
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0139 0.0135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0431 0.2585 0.3414
Echinococcus multilocularis g-protein coupled receptor 0.0431 0.2585 0.2585
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.004 0.0178 0.0235
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0231 0.028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0431 0.2585 0.2585
Trypanosoma brucei Histone methylation protein DOT1, putative 0.0016 0.0035 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.006 0.0079
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0037 0.0018
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.06 0.0793
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0055 0.0072
Mycobacterium ulcerans epimerase 0.0021 0.0061 0.0031
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0558 0.0736
Loa Loa (eye worm) hypothetical protein 0.006 0.0305 0.0438
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0037 0.0041
Loa Loa (eye worm) melatonin receptor type 1A 0.0431 0.2585 0.3716
Echinococcus granulosus peptide allatostatin:somatostatin 0.0431 0.2585 0.3414
Echinococcus granulosus pyruvate kinase 0.0033 0.0139 0.0183
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0139 0.0165
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0399 0.239 0.2956
Chlamydia trachomatis pyruvate kinase 0.0033 0.0139 0.0135
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.1242 0.757 0.9381
Loa Loa (eye worm) hypothetical protein 0.0148 0.0846 0.1216
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0055 0.0072
Schistosoma mansoni smad 0.0024 0.0081 0.0108
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0081 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0055 0.0065
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Echinococcus multilocularis neuropeptides capa receptor 0.0431 0.2585 0.2585
Schistosoma mansoni pyruvate kinase 0.0033 0.0139 0.0183
Echinococcus granulosus biogenic amine 5HT receptor 0.0431 0.2585 0.3414
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.004 0.0178 0.0213
Brugia malayi Tachykinin-like peptides receptor 99D 0.0431 0.2585 0.3414
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0055 0.0072
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0055 0.0072
Brugia malayi MH1 domain containing protein 0.0024 0.0081 0.0108
Onchocerca volvulus 0.0431 0.2585 0.8987
Echinococcus multilocularis neuropeptide FF receptor 2 0.0431 0.2585 0.2585
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0139 0.0199
Brugia malayi MAP kinase sur-1 0.0051 0.0249 0.0329
Loa Loa (eye worm) hypothetical protein 0.002 0.0055 0.0078
Echinococcus granulosus tm gpcr rhodopsin 0.0431 0.2585 0.3414
Schistosoma mansoni regulator of G protein signaling 0.002 0.0055 0.0072
Schistosoma mansoni regulator of G protein signaling 0.002 0.0055 0.0072
Toxoplasma gondii AGC kinase 0.004 0.0178 0.0204
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0114 0.0102
Onchocerca volvulus 0.0479 0.2876 1
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0055 0.0078
Echinococcus multilocularis fmrfamide receptor 0.0431 0.2585 0.2585
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0798 0.4837 0.6387
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0055 0.0072
Echinococcus multilocularis conserved hypothetical protein 0.0688 0.4164 0.4164
Onchocerca volvulus 0.0431 0.2585 0.8987
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.06 0.0748
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0037 0.0018
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0081 0.0108
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0055 0.0065
Schistosoma mansoni hypothetical protein 0.0431 0.2585 0.3414
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0049 0.0049
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0431 0.2585 0.3414
Echinococcus granulosus smad 0.0024 0.0081 0.0108
Schistosoma mansoni amine GPCR 0.0431 0.2585 0.3414
Brugia malayi G-protein coupled receptor 0.0431 0.2585 0.3414
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.004 0.0178 0.0213
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0431 0.2585 0.2585
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.1242 0.757 1
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0843 0.5115 0.7353
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0431 0.2585 0.3414
Schistosoma mansoni microtubule-associated protein tau 0.0688 0.4164 0.55
Onchocerca volvulus 0.0431 0.2585 0.8987
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.1323 0.807 1
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.1242 0.757 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0081 0.0108
Brugia malayi RE15519p 0.0431 0.2585 0.3414
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0037 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0114 0.0143
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.004 0.0178 0.0213
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0223 0.0223
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0139 0.0165
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0039 0.0172 0.0227
Loa Loa (eye worm) hypothetical protein 0.0033 0.0139 0.0199
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0249 0.0302
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Brugia malayi intermediate filament protein 0.0027 0.0099 0.0131
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0305 0.0402
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0037 0.0039
Brugia malayi Pre-SET motif family protein 0.042 0.2518 0.3326
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus granulosus histone h3 methyltransferase 0.0129 0.0729 0.0963
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0055 0.0065
Schistosoma mansoni amine GPCR 0.0431 0.2585 0.3414
Onchocerca volvulus 0.0431 0.2585 0.8987
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.06 0.0786
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0223 0.0294
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0223 0.0294
Schistosoma mansoni hypothetical protein 0.0047 0.0223 0.0294
Plasmodium vivax SET domain protein, putative 0.006 0.0305 0.0371
Loa Loa (eye worm) MH2 domain-containing protein 0.0352 0.2097 0.3015
Schistosoma mansoni hypothetical protein 0.0047 0.0223 0.0294
Trypanosoma brucei histone-lysine n-methyltransferase 0.0016 0.0035 0.0036
Schistosoma mansoni pyruvate kinase 0.0017 0.0039 0.0052
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0038 0.0169 0.0193
Echinococcus multilocularis musashi 0.0027 0.0099 0.0099
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0049 0.0016
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0431 0.2585 0.2585
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.004 0.0178 0.0178
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0249 0.0302
Loa Loa (eye worm) transcription factor SMAD2 0.0352 0.2097 0.3015
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.1242 0.757 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.001 0.0013
Echinococcus granulosus dro:myosuppressin receptor 0.0431 0.2585 0.3414
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0114 0.0102
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0231 0.0306
Toxoplasma gondii exonuclease III APE 0.0019 0.0049 0.0034
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0431 0.2585 0.2585
Schistosoma mansoni growth hormone secretagogue receptor 0.0431 0.2585 0.3414
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0023 0.0033
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0068 0.009
Echinococcus granulosus pyruvate kinase 0.0033 0.0139 0.0183
Onchocerca volvulus 0.006 0.0305 0.1059
Echinococcus granulosus neuropeptide receptor 0.0431 0.2585 0.3414
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0846 0.1118
Echinococcus multilocularis high affinity choline transporter 1 0.0347 0.2065 0.2065
Schistosoma mansoni intermediate filament proteins 0.0027 0.0099 0.0131
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0055 0.0072
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.1242 0.757 0.9381
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0249 0.0358
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0431 0.2585 0.3414
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0431 0.2585 0.3716
Loa Loa (eye worm) hypothetical protein 0.002 0.0055 0.0078
Loa Loa (eye worm) hypothetical protein 0.0129 0.0729 0.1049
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.06 0.0748
Echinococcus granulosus Ankyrin 0.0029 0.0114 0.0151
Trypanosoma brucei Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0016 0.0035 0.0036
Onchocerca volvulus 0.0038 0.0169 0.0588
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0249 0.0282
Mycobacterium ulcerans glutaminase 0.0277 0.1637 0.2124
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Onchocerca volvulus 0.0431 0.2585 0.8987
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0039
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0431 0.2585 0.2585
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.06 0.0737
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0431 0.2585 0.3414
Mycobacterium ulcerans hypothetical protein 0.0021 0.0061 0.0031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0016
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.1242 0.757 1
Echinococcus granulosus nuclear factor of activated T cells 5 0.0149 0.0848 0.112
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0016
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0431 0.2585 0.3414
Giardia lamblia Pyruvate kinase 0.0033 0.0139 0.0135
Schistosoma mansoni lamin 0.0027 0.0099 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0055 0.0065
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0055 0.0055
Echinococcus multilocularis allatostatin A receptor 0.0431 0.2585 0.2585
Echinococcus multilocularis lamin 0.0027 0.0099 0.0099
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.1242 0.757 0.9381
Onchocerca volvulus 0.0431 0.2585 0.8987
Brugia malayi MH2 domain containing protein 0.0024 0.0081 0.0108
Schistosoma mansoni neuropeptide f receptor 76f 0.0431 0.2585 0.3414
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0114 0.0143
Echinococcus granulosus sodium:myo inositol cotransporter 0.0038 0.0169 0.0223
Schistosoma mansoni lamin 0.0027 0.0099 0.0131
Schistosoma mansoni hypothetical protein 0.0431 0.2585 0.3414
Echinococcus multilocularis serotonin receptor 0.0431 0.2585 0.2585
Echinococcus granulosus GPCR family 2 0.0047 0.0223 0.0294
Brugia malayi sulfakinin receptor protein 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Loa Loa (eye worm) RGS-3 protein 0.002 0.0055 0.0078
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.0059
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.1242 0.757 1
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Plasmodium falciparum thioredoxin reductase 0.0048 0.0231 0.0258
Brugia malayi Death domain containing protein 0.0029 0.0113 0.0149
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0231 0.0332
Schistosoma mansoni histamine h1 receptor 0.0431 0.2585 0.3414
Entamoeba histolytica hypothetical protein 0.002 0.0055 0.0065
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0068 0.0083
Echinococcus granulosus neuropeptide receptor A26 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus granulosus pyruvate kinase 0.0017 0.0039 0.0052
Toxoplasma gondii AGC kinase 0.004 0.0178 0.0204
Echinococcus multilocularis g protein coupled receptor 0.0431 0.2585 0.2585
Schistosoma mansoni amine GPCR 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0023 0.0077 0.011
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.006 0.006
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0431 0.2585 0.3716
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0123 0.0688 0.27
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0055 0.0072
Loa Loa (eye worm) TYRA-2 protein 0.0431 0.2585 0.3716
Echinococcus granulosus neuropeptide s receptor 0.0431 0.2585 0.3414
Onchocerca volvulus 0.0027 0.0099 0.0346
Trypanosoma brucei trypanothione reductase 0.0048 0.0231 0.028
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0139 0.0199
Echinococcus granulosus g-protein coupled receptor 0.0431 0.2585 0.3414
Brugia malayi neuropeptide F receptor 0.0431 0.2585 0.3414
Echinococcus granulosus hypothetical protein 0.1119 0.6814 0.9001
Brugia malayi Thioredoxin reductase 0.0048 0.0231 0.0306
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0798 0.4837 0.6954
Echinococcus multilocularis rhodopsin orphan GPCR 0.0431 0.2585 0.2585
Trypanosoma cruzi Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0016 0.0035 0.0036
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Mycobacterium ulcerans endonuclease IV 0.0078 0.0416 0.0503
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0223 0.0294
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.006 0.0079
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.06 0.0793
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0416 0.0503
Entamoeba histolytica hypothetical protein 0.002 0.0055 0.0065
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Brugia malayi neuropeptide F receptor 0.0431 0.2585 0.3414
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0431 0.2585 0.3414
Brugia malayi G-protein coupled receptor 0.0431 0.2585 0.3414
Echinococcus granulosus tm gpcr rhodopsin 0.0431 0.2585 0.3414
Loa Loa (eye worm) AGC/PKA protein kinase 0.004 0.0178 0.0255
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0114 0.012
Echinococcus multilocularis fmrfamide receptor 0.0431 0.2585 0.2585
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0798 0.4837 0.6387
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0399 0.239 0.2956
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0223 0.032
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0055 0.0055
Echinococcus granulosus axis inhibition protein axin 0.002 0.0055 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0431 0.2585 0.3414
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.0416 0.1615
Echinococcus granulosus rhodopsin orphan GPCR 0.0431 0.2585 0.3414
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0798 0.4837 0.6954
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.1242 0.757 1
Schistosoma mansoni opsin-like receptor 0.0431 0.2585 0.3414
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.004 0.0178 0.0213
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0087
Echinococcus multilocularis pyruvate kinase 0.0017 0.0039 0.0039
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0431 0.2585 0.3414
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0023 0.003
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Schistosoma mansoni opsin-like receptor 0.0431 0.2585 0.3414
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.1242 0.757 0.9381
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0114 0.012
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0291 0.0384
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Schistosoma mansoni hypothetical protein 0.0047 0.0223 0.0294
Onchocerca volvulus 0.0431 0.2585 0.8987
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0431 0.2585 0.2585
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0398 0.2382 1
Echinococcus multilocularis neuropeptide Y receptor 0.0431 0.2585 0.2585
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0249 0.0299
Toxoplasma gondii endonuclease IV APN 0.0078 0.0416 0.052
Loa Loa (eye worm) hypothetical protein 0.004 0.0178 0.0255
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0249 0.0322
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0113 0.0149
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0149 0.0848 0.0848
Echinococcus multilocularis rhodopsin orphan GPCR 0.0431 0.2585 0.2585
Plasmodium vivax glutathione reductase, putative 0.0048 0.0231 0.0274
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0038 0.0169 0.0169
Echinococcus multilocularis pyruvate kinase 0.0017 0.0039 0.0039
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0055 0.0055
Echinococcus granulosus death domain containing protein 0.0029 0.0113 0.0149
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.0612 0.2375
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0431 0.2585 0.3414
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus granulosus expressed protein 0.0382 0.228 0.3011
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0029 0.0113 0.0149
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0061 0.008
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0249 0.0302
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.1242 0.757 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0431 0.2585 0.2585
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0037 0.0039
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0049 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0431 0.2585 0.2585
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0055 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0178 0.0235
Onchocerca volvulus 0.0431 0.2585 0.8987
Echinococcus multilocularis Ankyrin 0.0029 0.0114 0.0114
Onchocerca volvulus 0.0431 0.2585 0.8987
Trichomonas vaginalis glutaminase, putative 0.0277 0.1637 0.2157
Schistosoma mansoni neuropeptide receptor 0.0431 0.2585 0.3414
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.0416 0.1529
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0431 0.2585 0.2585
Schistosoma mansoni hypothetical protein 0.0029 0.0113 0.0149
Brugia malayi GH02984p 0.0347 0.2065 0.2727
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0114 0.0143
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0431 0.2585 0.2585
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0431 0.2585 0.3414
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0249 0.0302
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0039
Schistosoma mansoni high-affinity choline transporter 0.0347 0.2065 0.2727
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0305 0.0402
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0055 0.0078
Echinococcus granulosus fmrfamide receptor 0.0431 0.2585 0.3414
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0055 0.0072
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0431 0.2585 0.2585
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0143
Brugia malayi Dopamine receptor protein 1 0.0431 0.2585 0.3414
Echinococcus multilocularis G-protein coupled receptor, putative 0.0431 0.2585 0.2585
Brugia malayi glutathione reductase 0.0048 0.0231 0.0306
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0139 0.0151
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0081 0.0108
Loa Loa (eye worm) hypothetical protein 0.002 0.0055 0.0078
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.1242 0.757 0.9381
Brugia malayi MH1 domain containing protein 0.0013 0.0016 0.0021
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0077 0.011
Leishmania major histone-lysine N-methyltransferase, putative 0.0016 0.0035 0.0036
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.06 0.0793
Loa Loa (eye worm) RecQ helicase 0.0022 0.0068 0.0098
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0123 0.0688 0.2774
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0055 0.0072
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.06 0.2402
Schistosoma mansoni amine GPCR 0.0431 0.2585 0.3414
Brugia malayi 6-phosphofructokinase 0.0108 0.06 0.0793
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0049 0.0054
Brugia malayi MH1 domain containing protein 0.0024 0.0081 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0249 0.0322
Loa Loa (eye worm) hypothetical protein 0.002 0.0055 0.0078
Schistosoma mansoni hypothetical protein 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Brugia malayi putative neuropeptide receptor 0.0431 0.2585 0.3414
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0014 0.0014
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0431 0.2585 0.3414
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.1242 0.757 0.9381
Entamoeba histolytica PH domain containing protein kinase, putative 0.004 0.0178 0.0227
Schistosoma mansoni ankyrin 23/unc44 0.0029 0.0113 0.0149
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0049 0.0058
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.06 0.0737
Echinococcus granulosus 7tm_1 domain containing protein 0.0431 0.2585 0.3414
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.06 0.0786
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0014 0.0018
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.1323 0.807 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0114 0.0143
Schistosoma mansoni hypothetical protein 0.0101 0.0558 0.0736
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0037 0.0039
Schistosoma mansoni regulator of G protein signaling 0.002 0.0055 0.0072
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0305 0.0402
Onchocerca volvulus 0.0431 0.2585 0.8987
Echinococcus granulosus G protein coupled receptor 139 0.0431 0.2585 0.3414
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.004 0.0178 0.0203
Toxoplasma gondii hypothetical protein 0.0016 0.0035 0.0015
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0844 0.5123 0.6751
Mycobacterium tuberculosis Probable reductase 0.011 0.0612 0.2452
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0081 0.0117
Echinococcus multilocularis netrin receptor unc 5 0.0029 0.0113 0.0113
Echinococcus multilocularis pyruvate kinase 0.0017 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.1242 0.757 1
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0139 0.0433
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0049 0.0058
Brugia malayi Dopamine receptor 0.0431 0.2585 0.3414
Brugia malayi MH1 domain containing protein 0.0013 0.0016 0.0021
Brugia malayi ORL1-like opioid receptor 0.0431 0.2585 0.3414
Echinococcus granulosus bloom syndrome protein 0.0022 0.0068 0.009
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0077 0.0094
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.1242 0.757 1
Schistosoma mansoni inositol transporter 0.0038 0.0169 0.0223
Echinococcus granulosus serotonin receptor 0.0431 0.2585 0.3414
Echinococcus granulosus axis inhibition protein axin 0.002 0.0055 0.0072
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0114 0.0143
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0049 0.0065
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0431 0.2585 0.3414
Echinococcus multilocularis rhodopsin orphan GPCR 0.0431 0.2585 0.2585
Leishmania major protein kinase A catalytic subunit isoform 1 0.004 0.0178 0.0213
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.1242 0.757 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0022
Echinococcus multilocularis neuropeptide s receptor 0.0431 0.2585 0.2585
Schistosoma mansoni neuropeptide receptor 0.0431 0.2585 0.3414
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0055 0.0065
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0431 0.2585 0.2585
Trypanosoma cruzi histone-lysine N-methyltransferase, putative 0.0016 0.0035 0.0036
Giardia lamblia Pyruvate kinase 0.0017 0.0039 0.0003
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0445 0.2667 0.3523
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0431 0.2585 0.2585
Schistosoma mansoni hypothetical protein 0.0047 0.0223 0.0294
Mycobacterium tuberculosis Probable oxidoreductase 0.0123 0.0688 0.2774
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0139 0.0482
Echinococcus multilocularis rhodopsin orphan GPCR 0.0431 0.2585 0.2585
Schistosoma mansoni neuropeptide F-like receptor 0.0431 0.2585 0.3414
Echinococcus granulosus netrin receptor unc 5 0.0029 0.0113 0.0149
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0055 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0431 0.2585 0.3414
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0016 0.0035 0.0036
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0431 0.2585 0.8987
Brugia malayi G protein-coupled receptor 0.0431 0.2585 0.3414
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.004 0.0178 0.0178
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.1242 0.757 1
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Brugia malayi Dopamine receptor protein 2 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.06 0.0786
Echinococcus granulosus 7TM GPCR rhodopsin 0.0431 0.2585 0.3414
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.1242 0.757 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0431 0.2585 0.3414
Echinococcus granulosus high affinity choline transporter 1 0.0347 0.2065 0.2727
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0231 0.0274
Echinococcus granulosus neuropeptide receptor 0.0431 0.2585 0.3414
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.1242 0.757 1
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.1242 0.757 0.9381
Schistosoma mansoni biogenic amine (5HT) receptor 0.0431 0.2585 0.3414
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0061 0.0031
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0029 0.0113 0.0113
Echinococcus granulosus neuropeptide Y receptor 0.0431 0.2585 0.3414
Echinococcus multilocularis neuropeptide Y receptor 0.0431 0.2585 0.2585
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0055 0.0072
Schistosoma mansoni regulator of G protein signaling 0.002 0.0055 0.0072
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0305 0.0305
Echinococcus granulosus pyruvate kinase 0.0017 0.0039 0.0052
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.1242 0.757 0.9381
Onchocerca volvulus 0.0431 0.2585 0.8987
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus multilocularis histone h3 methyltransferase 0.0129 0.0729 0.0729
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0055 0.0072
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0139 0.0152
Schistosoma mansoni hypothetical protein 0.0431 0.2585 0.3414
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0249 0.0329
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.1323 0.807 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.006 0.0087
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0798 0.4837 0.639
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.0612 0.2452
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0249 0.0329
Leishmania major protein kinase A catalytic subunit isoform 2 0.004 0.0178 0.0213
Echinococcus granulosus allatostatin A receptor 0.0431 0.2585 0.3414
Schistosoma mansoni smad1 5 8 and 0.0024 0.0081 0.0108
Schistosoma mansoni amine GPCR 0.0431 0.2585 0.3414
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0114 0.0143
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0431 0.2585 0.3414
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.0612 0.2452
Loa Loa (eye worm) glutaminase 0.0277 0.1637 0.2354
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0049 0.0054
Echinococcus granulosus Smad4 0.0024 0.0081 0.0108
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0399 0.239 0.2956
Entamoeba histolytica PH domain containing protein kinase, putative 0.004 0.0178 0.0227
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.1242 0.757 1
Schistosoma mansoni myosin xvIII 0.0431 0.2585 0.3414
Onchocerca volvulus Neuropeptide F receptor homolog 0.0431 0.2585 0.8987
Brugia malayi Serotonin receptor 0.089 0.5404 0.7139
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0049 0.0071
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.004 0.0053
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0231 0.0828
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.1242 0.757 1
Echinococcus granulosus sodium:glucose cotransporter 0.0038 0.0169 0.0223
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.06 0.0863
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0029 0.0114 0.0151
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.06 0.0786
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0052 0.002
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.06 0.0786
Brugia malayi G protein-coupled receptor F59B2.13 0.0431 0.2585 0.3414
Brugia malayi larval opioid receptor 0.0431 0.2585 0.3414
Brugia malayi glutaminase DH11.1 0.0277 0.1637 0.2163
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0055 0.0055
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0049
Schistosoma mansoni histone J3 methyltransferase 0.0129 0.0729 0.0963
Brugia malayi Protein kinase domain containing protein 0.003 0.0118 0.0156
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0139 0.0183
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0055 0.0072
Leishmania major pyruvate kinase 0.0033 0.0139 0.0165
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0114 0.0118
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0049 0.0054
Echinococcus multilocularis solute carrier family 5 0.0038 0.0169 0.0169
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0049 0.0065
Brugia malayi AKH receptor 0.0431 0.2585 0.3414
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Echinococcus multilocularis pyruvate kinase 0.0033 0.0139 0.0139
Schistosoma mansoni pyruvate kinase 0.0033 0.0139 0.0183
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0114 0.0102
Echinococcus multilocularis neuropeptide receptor 0.0431 0.2585 0.2585
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.06 0.06
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0055 0.0065
Schistosoma mansoni Smad4 0.0024 0.0081 0.0108
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.06 0.0863
Loa Loa (eye worm) hypothetical protein 0.0101 0.0558 0.0802
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0445 0.2667 0.3518
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0139 0.0183
Echinococcus granulosus lamin 0.0027 0.0099 0.0131
Loa Loa (eye worm) nuclear factor I 0.0013 0.0016 0.0022
Onchocerca volvulus 0.0027 0.0099 0.0346
Echinococcus granulosus g protein coupled receptor 0.0431 0.2585 0.3414
Schistosoma mansoni biogenic amine receptor 0.0431 0.2585 0.3414
Echinococcus granulosus biogenic amine 5HT receptor 0.0431 0.2585 0.3414
Leishmania major hypothetical protein, conserved 0.0016 0.0035 0.0036
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0431 0.2585 0.3414
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0114 0.0102
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1142 0.6956 1
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0398 0.2382 1
Trypanosoma brucei protein kinase, putative 0.0051 0.0249 0.0302
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.1242 0.757 1
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.004 0.0178 0.0204
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.004 0.0178 0.0213
Echinococcus multilocularis Smad4 0.0024 0.0081 0.0081
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0431 0.2585 0.3716
Giardia lamblia Kinase, AGC PKA 0.004 0.0178 0.0187
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0049 0.0052
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.1242 0.757 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0249 0.0249
Schistosoma mansoni axis inhibition protein axin 0.002 0.0055 0.0072
Brugia malayi Pre-SET motif family protein 0.006 0.0305 0.0402
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0055 0.0055
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0123 0.0688 0.2774
Echinococcus multilocularis expressed protein 0.0382 0.228 0.228
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0431 0.2585 0.3414
Echinococcus granulosus microtubule associated protein 2 0.0688 0.4164 0.55
Brugia malayi MH2 domain containing protein 0.0024 0.0081 0.0108
Echinococcus granulosus intermediate filament protein 0.0027 0.0099 0.0131
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0249 0.0302
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0055 0.0078
Echinococcus granulosus tm gpcr rhodopsin 0.0431 0.2585 0.3414
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0114 0.0118
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.1242 0.757 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.004 0.0178 0.0255
Plasmodium falciparum glutathione reductase 0.0048 0.0231 0.0258
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.1323 0.807 1
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Brugia malayi Histone-lysine N-methyltransferase, H3 lysine-79 specific 0.0129 0.0729 0.0963
Loa Loa (eye worm) hypothetical protein 0.0026 0.0096 0.0139
Loa Loa (eye worm) glutaminase 2 0.0277 0.1637 0.2354
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0431 0.2585 0.3414
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0249 0.0322
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0139 0.0165
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0039 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0113 0.0162
Brugia malayi hypothetical protein 0.0124 0.0699 0.0923
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.004 0.0178 0.0213
Echinococcus multilocularis microtubule associated protein 2 0.0688 0.4164 0.4164
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.06 0.0786
Schistosoma mansoni neuropeptide receptor 0.0431 0.2585 0.3414
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0431 0.2585 0.3414
Brugia malayi putative neuropeptide receptor NPR1 0.0431 0.2585 0.3414
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0431 0.2585 0.3414
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.1242 0.757 0.757
Echinococcus granulosus g protein coupled receptor 0.0431 0.2585 0.3414
Toxoplasma gondii thioredoxin reductase 0.0048 0.0231 0.0275
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.1242 0.757 0.9381
Echinococcus multilocularis g protein coupled receptor 0.0431 0.2585 0.2585
Brugia malayi Uncoordinated protein 44 0.0029 0.0113 0.0149
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0055 0.0055
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.1242 0.757 0.9381
Brugia malayi PXA domain containing protein 0.002 0.0055 0.0072
Echinococcus granulosus neuropeptide Y receptor 0.0431 0.2585 0.3414
Brugia malayi Serotonin receptor 0.0431 0.2585 0.3414
Brugia malayi Melatonin receptor type 1A 0.0431 0.2585 0.3414
Schistosoma mansoni smad1 5 8 and 0.0024 0.0081 0.0108
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0039 0.0172 0.0172
Chlamydia trachomatis endonuclease IV 0.0078 0.0416 0.0503
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0139 0.0482
Schistosoma mansoni smad1 5 8 and 0.0024 0.0081 0.0108
Echinococcus multilocularis G protein coupled receptor 139 0.0431 0.2585 0.2585
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0081 0.0081
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.006 0.0079
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0016 0.0035 0.0036
Schistosoma mansoni ap endonuclease 0.0019 0.0049 0.0065
Echinococcus multilocularis pyruvate kinase 0.0033 0.0139 0.0139
Echinococcus granulosus sodium:glucose cotransporter 2 0.0038 0.0169 0.0223
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0039
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.004 0.0178 0.0235
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.1242 0.757 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0055 0.0078
Brugia malayi MH2 domain containing protein 0.0352 0.2097 0.277
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.004 0.0178 0.0178
Echinococcus multilocularis orexin receptor type 2 0.0431 0.2585 0.2585
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Entamoeba histolytica hypothetical protein 0.002 0.0055 0.0065
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0099 0.0143
Echinococcus granulosus sex peptide receptor 0.0431 0.2585 0.3414
Echinococcus granulosus somatostatin receptor 0.0431 0.2585 0.3414
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0305 0.0402
Loa Loa (eye worm) hypothetical protein 0.0047 0.0223 0.032
Brugia malayi 6-phosphofructokinase 0.0108 0.06 0.0793
Echinococcus multilocularis neuropeptides capa receptor 0.0431 0.2585 0.2585
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.1242 0.757 1
Onchocerca volvulus Netrin receptor homolog 0.0029 0.0113 0.0392
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.06 0.2324
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0798 0.4837 0.4837
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0037 0.0049
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0039
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0037 0.0041
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0039
Brugia malayi Smad1 0.0024 0.0081 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0249 0.0322
Loa Loa (eye worm) hypothetical protein 0.0029 0.0113 0.0162
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.004 0.0178 0.0187
Brugia malayi hypothetical protein 0.002 0.0055 0.0072
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0399 0.239 0.3156
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0431 0.2585 0.2585
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.0612 0.2452
Schistosoma mansoni adenoreceptor 0.0431 0.2585 0.3414
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0049
Brugia malayi follicle stimulating hormone receptor 0.1142 0.6956 0.9188
Echinococcus granulosus g protein coupled receptor 0.0431 0.2585 0.3414
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0037 0.0039
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0431 0.2585 0.2585
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0249 0.0302
Echinococcus granulosus neuropeptides capa receptor 0.0431 0.2585 0.3414
Echinococcus granulosus orexin receptor type 2 0.0431 0.2585 0.3414
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0055 0.0055
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0431 0.2585 0.3414
Loa Loa (eye worm) neuropeptide F receptor 0.0431 0.2585 0.3716
Echinococcus granulosus pyruvate kinase 0.0017 0.0039 0.0052
Schistosoma mansoni biogenic amine (5HT) receptor 0.0431 0.2585 0.3414
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0431 0.2585 0.3414
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0037 0.0039
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0846 0.1216
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0431 0.2585 0.3414
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.1242 0.757 1
Schistosoma mansoni glutaminase 0.0277 0.1637 0.2163
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.1242 0.757 0.757
Echinococcus granulosus rhodopsin orphan GPCR 0.0431 0.2585 0.3414
Brugia malayi hypothetical protein 0.0431 0.2585 0.3414
Echinococcus granulosus rhodopsin orphan GPCR 0.0431 0.2585 0.3414
Brugia malayi PXA domain containing protein 0.002 0.0055 0.0072
Echinococcus multilocularis smad 0.0024 0.0081 0.0081
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0431 0.2585 0.3414
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0431 0.2585 0.3414
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0055 0.0065
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0399 0.239 0.2956
Schistosoma mansoni biogenic amine receptor 0.0431 0.2585 0.3414
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0139 0.0165
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0081 0.0117
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Schistosoma mansoni biogenic amine receptor 0.0431 0.2585 0.3414
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0114 0.012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0049 0.0033
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0039 0.0019
Echinococcus multilocularis dro:myosuppressin receptor 0.0431 0.2585 0.2585
Echinococcus granulosus alpha 1A adrenergic receptor 0.0431 0.2585 0.3414
Onchocerca volvulus 0.0431 0.2585 0.8987
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0431 0.2585 0.3414
Echinococcus multilocularis serotonin receptor 0.0431 0.2585 0.2585
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0114 0.0143
Onchocerca volvulus 0.0431 0.2585 0.8987
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0049 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.006 0.0079
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Schistosoma mansoni ap endonuclease 0.0019 0.0049 0.0065
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0139 0.0176
Leishmania major pyruvate kinase 0.0033 0.0139 0.0165
Schistosoma mansoni axis inhibition protein axin 0.002 0.0055 0.0072
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0039 0.002
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.1242 0.757 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0061 0.0101
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0431 0.2585 0.3414
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.001 0.0013
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0038 0.0169 0.0223
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0231 0.0231
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0114 0.0143
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.06 0.0737
Loa Loa (eye worm) hypothetical protein 0.0078 0.0416 0.0598
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0037 0.0016
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0061 0.0211
Brugia malayi hypothetical protein 0.002 0.0055 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0169 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0178 0.0235
Loa Loa (eye worm) hypothetical protein 0.0431 0.2585 0.3716
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.1242 0.757 0.9381
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0249 0.0302
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0431 0.2585 0.3414
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0038 0.0169 0.0169
Schistosoma mansoni neuropeptide F-like receptor 0.0431 0.2585 0.3414
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0431 0.2585 0.2585
Echinococcus multilocularis somatostatin receptor 0.0431 0.2585 0.2585
Brugia malayi Sodium:solute symporter family protein 0.0038 0.0169 0.0223
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.06 0.0786
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0139 0.0176
Schistosoma mansoni regulator of G protein signaling 0.002 0.0055 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0305 0.0402
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.0612 0.2452
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0114 0.0102
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0431 0.2585 0.2585
Plasmodium falciparum pyruvate kinase 0.0033 0.0139 0.0135
Leishmania major trypanothione reductase 0.0048 0.0231 0.028
Loa Loa (eye worm) hypothetical protein 0.0798 0.4837 0.6954
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0431 0.2585 0.3414
Trichomonas vaginalis set domain proteins, putative 0.0478 0.2875 0.3792

Activities

Activity type Activity value Assay description Source Reference
logP (ADMET) = 3.17 Partition coefficient (logP) ChEMBL. 11378354

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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