Detailed information for compound 511185

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 440.414 | Formula: C24H19F3N2O3
  • H donors: 1 H acceptors: 2 LogP: 5.91 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)c1nc2c(o1)c(C)cc(c2)C)COc1ccc(cc1)C(F)(F)F
  • InChi: 1S/C24H19F3N2O3/c1-14-11-15(2)22-20(12-14)29-23(32-22)16-3-7-18(8-4-16)28-21(30)13-31-19-9-5-17(6-10-19)24(25,26)27/h3-12H,13H2,1-2H3,(H,28,30)
  • InChiKey: PSNVVJGNYPKRDN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cholesteryl ester transfer protein, plasma Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus g protein coupled receptor 0.0063 0.036 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0172 0.0172
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.036 0.0525
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0051 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0061
Echinococcus granulosus geminin 0.0154 0.0983 0.1432
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0061
Echinococcus granulosus chromobox protein 1 0.0063 0.0362 0.0528
Entamoeba histolytica hypothetical protein 0.001 0.000000000050372 0.000000000052807
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0061 0.0089
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0033 0.0153 0.0222
Onchocerca volvulus 0.0063 0.036 0.1342
Onchocerca volvulus 0.0404 0.2684 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.0378
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.036 0.0378
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0189 0.0634
Echinococcus multilocularis sex peptide receptor 0.0063 0.036 0.0525
Schistosoma mansoni blooms syndrome DNA helicase 0.0034 0.0163 0.0171
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0016
Onchocerca volvulus 0.0063 0.036 0.1342
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0023 0.0088 0.0128
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0058 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0295 0.1941 0.2828
Echinococcus granulosus carbonic anhydrase II 0.1016 0.6863 1
Schistosoma mansoni hypothetical protein 0.0014 0.0027 0.0028
Brugia malayi hypothetical protein 0.0023 0.0086 0.0125
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0061 0.0064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0043 0.0043
Echinococcus multilocularis serotonin receptor 0.0426 0.284 0.4137
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0058 0.0195
Brugia malayi 6-phosphofructokinase 0.0109 0.0676 0.0985
Onchocerca volvulus 0.0027 0.0114 0.0426
Trichomonas vaginalis flap endonuclease-1, putative 0.0024 0.0091 0.0091
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0042 0.014
Loa Loa (eye worm) hypothetical protein 0.0027 0.0111 0.0162
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0086 0.0288
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.0911 0.6152 0.9298
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0058 0.2295
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.036 0.0525
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.008 0.0117
Schistosoma mansoni biogenic amine receptor 0.0063 0.036 0.0378
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0086 0.0288
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.036 0.0525
Echinococcus granulosus expressed protein 0.0376 0.2494 0.3633
Loa Loa (eye worm) hypothetical protein 0.0447 0.2984 0.4348
Brugia malayi hypothetical protein 0.0023 0.0088 0.0128
Brugia malayi Cytochrome P450 family protein 0.0023 0.0084 0.0123
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0244 0.0356
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.036 0.0525
Echinococcus multilocularis chromobox protein 1 0.0063 0.0362 0.0528
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.000000000050372 0.000000000050372
Schistosoma mansoni zinc finger protein 0.0014 0.0024 0.0025
Brugia malayi Bromodomain containing protein 0.0032 0.0147 0.0215
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0753 0.1082
Echinococcus multilocularis neuropeptide receptor 0.0063 0.036 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0101 0.0101
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.0676 0.0985
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0183 0.0266
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0127 0.0185
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0041 0.0207 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.0075
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0023 0.0088 0.0128
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0069
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0753 0.1082
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1016 0.6863 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.012 0.0174
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0016 0.0035 0.0051
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.008 0.0084
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus multilocularis Chromo domain 0.001 0.000000000050372 0.000000000073394
Brugia malayi larval opioid receptor 0.0063 0.036 0.0525
Echinococcus granulosus neuropeptide s receptor 0.0482 0.3222 0.4694
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0063 0.036 0.0525
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0058 0.0025
Trypanosoma brucei C-8 sterol isomerase, putative 0.0371 0.2459 0.356
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0042 0.0025
Echinococcus granulosus microtubule associated protein 2 0.0694 0.4671 0.6805
Onchocerca volvulus 0.0041 0.0207 0.077
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0051 0.0075
Giardia lamblia Histone acetyltransferase GCN5 0.0036 0.0172 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0033 0.0153 0.0222
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0027 0.004
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1016 0.6863 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0051 0.0075
Brugia malayi hypothetical protein 0.0019 0.0061 0.0089
Plasmodium vivax hypothetical protein, conserved 0.001 0.000000000050372 0.0000000019835
Brugia malayi Associated with TFs and helicases family protein 0.001 0.000000000050372 0.000000000073394
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.0356
Echinococcus granulosus sex peptide receptor 0.0063 0.036 0.0525
Echinococcus granulosus g-protein coupled receptor 0.0063 0.036 0.0525
Entamoeba histolytica acetyltransferase, GNAT family 0.0036 0.0172 0.018
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.2642 0.385
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0058 0.0058
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0061 0.0089
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Schistosoma mansoni opsin-like receptor 0.0063 0.036 0.0378
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0061
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.036 0.0525
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0063 0.036 0.0378
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0058 0.0036
Echinococcus multilocularis jumonji domain containing protein 0.0037 0.0181 0.0264
Leishmania major carbonic anhydrase-like protein 0.1016 0.6863 0.7188
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0002 0.0004
Onchocerca volvulus 0.0041 0.0207 0.077
Schistosoma mansoni opsin-like receptor 0.0063 0.036 0.0378
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0061 0.0089
Onchocerca volvulus 0.0063 0.036 0.1342
Brugia malayi Type III restriction enzyme, res subunit family protein 0.001 0.000000000050372 0.000000000073394
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0045 0.0239 0.0348
Echinococcus multilocularis fmrfamide receptor 0.0063 0.036 0.0525
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0064
Onchocerca volvulus 0.0028 0.012 0.0445
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0131 0.0438
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0676 0.0985
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0086 0.009
Loa Loa (eye worm) carbonic anhydrase 3 0.1016 0.6863 1
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0254 0.037
Schistosoma mansoni neuropeptide receptor 0.0063 0.036 0.0378
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0042 0.0018
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0183 0.0266
Echinococcus granulosus neuropeptide FF receptor 2 0.0063 0.036 0.0525
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0676 0.0709
Onchocerca volvulus 0.0063 0.036 0.1342
Brugia malayi Pre-SET motif family protein 0.0031 0.0138 0.0202
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0061 0.0064
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0023 0.0088 0.0128
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Brugia malayi Dopamine receptor 0.0063 0.036 0.0525
Plasmodium falciparum phd finger protein, putative 0.0027 0.011 0.037
Plasmodium vivax flap endonuclease 1, putative 0.0024 0.0091 0.3586
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0063 0.036 0.0525
Loa Loa (eye worm) TYRA-2 protein 0.0063 0.036 0.0525
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.036 0.0378
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0061 0.0089
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.011 0.037
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0131 1
Loa Loa (eye worm) hypothetical protein 0.0319 0.2109 0.3073
Loa Loa (eye worm) flap endonuclease-1 0.0024 0.0091 0.0133
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0134 0.0845 0.0886
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.004
Echinococcus granulosus intermediate filament protein 0.0027 0.0114 0.0167
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0816 0.5501 0.8015
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1016 0.6863 0.7195
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0012 0.0017
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0064
Onchocerca volvulus 0.0023 0.0088 0.0328
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0525
Schistosoma mansoni intermediate filament proteins 0.0027 0.0114 0.012
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0063 0.036 0.0525
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0063 0.036 0.0525
Schistosoma mansoni carbonic anhydrase-related 0.0447 0.2984 0.3128
Trichomonas vaginalis chromobox protein, putative 0.0038 0.019 0.019
Mycobacterium ulcerans carbonic anhydrase 0.1407 0.9539 0.9537
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0525
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0138 0.0202
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0131 0.6836
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0061 0.0089
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.019 0.071
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0042 0.014
Onchocerca volvulus 0.0041 0.0207 0.077
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0447 0.2984 0.4348
Onchocerca volvulus 0.0041 0.0207 0.077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0035 0.0168 0.0244
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0061 0.0089
Echinococcus multilocularis fmrfamide receptor 0.0063 0.036 0.0525
Schistosoma mansoni ap endonuclease 0.0019 0.0058 0.0061
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0084 0.0123
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0063 0.036 0.0378
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0023 0.0088 0.0128
Mycobacterium tuberculosis Beta-carbonic anhydrase 0.0979 0.6613 1
Echinococcus granulosus G protein coupled receptor 139 0.0063 0.036 0.0525
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0028 0.0041
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0064
Loa Loa (eye worm) MH2 domain-containing protein 0.0109 0.0672 0.0979
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0036 0.0172 0.0251
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0023 0.0033
Trypanosoma brucei carbonic anhydrase-like protein 0.1016 0.6863 1
Brugia malayi LBP/BPI 0.0017 0.0047 0.0069
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0061 0.0089
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0131 0.1406
Brugia malayi hypothetical protein 0.0017 0.0047 0.0069
Echinococcus granulosus flap endonuclease 1 0.0024 0.0091 0.0133
Echinococcus granulosus GPCR family 2 0.0014 0.0027 0.004
Loa Loa (eye worm) hypothetical protein 0.0189 0.1222 0.1781
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus cpg binding protein 0.0031 0.0142 0.0207
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.0051 0.0734
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.036 0.0525
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0061 0.0064
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.4671 0.6805
Loa Loa (eye worm) hypothetical protein 0.0447 0.2984 0.4348
Brugia malayi jmjC domain containing protein 0.0035 0.0171 0.025
Brugia malayi hypothetical protein 0.0404 0.2684 0.3911
Brugia malayi G-protein coupled receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0042 0.0042
Brugia malayi hypothetical protein 0.0019 0.0061 0.0089
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0089
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0061 0.0064
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0131 0.5152
Echinococcus granulosus jumonji domain containing protein 0.0037 0.0181 0.0264
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0061 0.0089
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0063 0.036 0.0525
Echinococcus granulosus Chromobox protein 3 0.001 0.0000000085911 0.000000012517
Echinococcus granulosus methyl CpG binding domain protein 2 0.0016 0.0035 0.0051
Entamoeba histolytica hypothetical protein 0.0019 0.0061 0.0064
Echinococcus granulosus neuropeptide receptor A26 0.0482 0.3222 0.4694
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0128
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0447 0.2984 0.4348
Schistosoma mansoni hypothetical protein 0.0063 0.036 0.0378
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0134 0.0845 0.1232
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0063 0.036 0.0525
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0032 0.0149 0.0217
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0225 0.0225
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0043 0.0043
Leishmania major carbonic anhydrase family protein, putative 0.1407 0.9539 1
Plasmodium falciparum flap endonuclease 1 0.0024 0.0091 0.0305
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0089
Plasmodium vivax ataxin-2 like protein, putative 0.0023 0.0086 0.3381
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus multilocularis g protein coupled receptor 0.0063 0.036 0.0525
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0018 0.0027
Onchocerca volvulus 0.0017 0.0047 0.0177
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.067 0.0956
Echinococcus granulosus lamin 0.0027 0.0114 0.0167
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus 7tm_1 domain containing protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0058 0.0085
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.036 0.0525
Echinococcus multilocularis lamin 0.0027 0.0114 0.0167
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0058 0.005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.036 0.0378
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0061 0.0089
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0014 0.0027 0.004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0128
Schistosoma mansoni hypothetical protein 0.0063 0.036 0.0378
Mycobacterium tuberculosis Probable reductase 0.0109 0.067 0.0956
Onchocerca volvulus 0.0063 0.036 0.1342
Schistosoma mansoni cpg binding protein 0.0031 0.0142 0.0149
Onchocerca volvulus Neuropeptide F receptor homolog 0.0063 0.036 0.1342
Echinococcus multilocularis somatostatin receptor 0.0063 0.036 0.0525
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0025
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0014 0.0027 0.004
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0024 0.0091 0.0098
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.0496 0.3316 0.4982
Echinococcus multilocularis dro:myosuppressin receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) transcription factor SMAD2 0.0109 0.0672 0.0979
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0676 0.0676
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.000000000050372 0.000000000050372
Leishmania major hypothetical protein, conserved 0.0023 0.0086 0.0065
Schistosoma mansoni neuropeptide receptor 0.0063 0.036 0.0378
Loa Loa (eye worm) hypothetical protein 0.0426 0.284 0.4137
Schistosoma mansoni hypothetical protein 0.0063 0.036 0.0378
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.0676 0.0965
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0525
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0333 0.0486
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.0378
Schistosoma mansoni chromobox protein 0.0063 0.0362 0.038
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0061 0.0089
Schistosoma mansoni zinc finger protein 0.0023 0.0084 0.0088
Echinococcus granulosus tachykinin peptides receptor 99D 0.0063 0.036 0.0525
Schistosoma mansoni biogenic amine receptor 0.0063 0.036 0.0378
Echinococcus multilocularis G protein coupled receptor 139 0.0063 0.036 0.0525
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0525
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0131 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0086 0.0125
Brugia malayi Melatonin receptor type 1A 0.0063 0.036 0.0525
Onchocerca volvulus 0.0063 0.036 0.1342
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0061 0.0089
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0028 0.0041
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0027
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0063 0.036 0.0378
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Schistosoma mansoni lozenge 0.0051 0.0275 0.0288
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0101 0.0101
Schistosoma mansoni biogenic amine receptor 0.0063 0.036 0.0378
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0051 0.0075
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.036 0.0378
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0061
Onchocerca volvulus 0.001 0.0000000085911 0.000000032006
Trichomonas vaginalis set domain proteins, putative 0.0239 0.1561 0.1561
Schistosoma mansoni neuropeptide receptor 0.0063 0.036 0.0378
Schistosoma mansoni hypothetical protein 0.0154 0.0983 0.1031
Plasmodium vivax SET domain protein, putative 0.0031 0.0138 0.5447
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0447 0.2984 0.4348
Schistosoma mansoni biogenic amine (5HT) receptor 0.0426 0.284 0.2977
Echinococcus granulosus biogenic amine 5HT receptor 0.0063 0.036 0.0525
Entamoeba histolytica hypothetical protein 0.0019 0.0061 0.0064
Schistosoma mansoni hypothetical protein 0.0447 0.2984 0.3128
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0051 0.0172
Giardia lamblia PHD finger protein 15 0.0027 0.011 0.5271
Schistosoma mansoni neuropeptide receptor 0.0063 0.036 0.0378
Loa Loa (eye worm) hypothetical protein 0.0112 0.0691 0.1007
Onchocerca volvulus 0.0041 0.0207 0.077
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0063 0.036 0.0378
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0069
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0225 0.0328
Schistosoma mansoni lamin 0.0027 0.0114 0.012
Loa Loa (eye worm) hypothetical protein 0.0046 0.024 0.035
Schistosoma mansoni histamine h1 receptor 0.0063 0.036 0.0378
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0087 0.0091
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0061 0.0089
Loa Loa (eye worm) latrophilin receptor protein 2 0.0014 0.0027 0.004
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0061 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.0378
Brugia malayi Calcitonin receptor-like protein seb-1 0.0045 0.0239 0.0348
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0525
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0525
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0087 0.0092
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0061 0.0089
Onchocerca volvulus 0.0239 0.1561 0.5815
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0447 0.2984 0.4348
Schistosoma mansoni amine GPCR 0.0063 0.036 0.0378
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0018
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0004
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0063 0.036 0.0525
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0042 0.164
Toxoplasma gondii hypothetical protein 0.0447 0.2984 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0063 0.036 0.0525
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0058 0.005
Onchocerca volvulus 0.0063 0.036 0.1342
Brugia malayi Putative carbonic anhydrase 5 precursor 0.1016 0.6863 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0043 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0131 0.0131
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0063 0.036 0.0525
Brugia malayi latrophilin 2 splice variant baaae 0.0031 0.0141 0.0206
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0051 0.0172
Brugia malayi phosphofructokinase 0.0109 0.0676 0.0985
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0333 0.0486
Schistosoma mansoni carbonic anhydrase 0.0447 0.2984 0.3128
Echinococcus granulosus biogenic amine 5HT receptor 0.0426 0.284 0.4137
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.036 0.0525
Schistosoma mansoni amine GPCR 0.0063 0.036 0.0378
Onchocerca volvulus 0.0041 0.0209 0.078
Schistosoma mansoni adenoreceptor 0.0063 0.036 0.0378
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.036 0.0378
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0131 0.0131
Brugia malayi putative neuropeptide receptor NPR1 0.0063 0.036 0.0525
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0087 0.0087
Onchocerca volvulus 0.0041 0.0207 0.077
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0161
Loa Loa (eye worm) glutathione reductase 0.0048 0.0254 0.037
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0371 0.2459 0.356
Giardia lamblia Flap structure-specific endonuclease 0.0024 0.0091 0.3787
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0023 0.0088 0.0128
Echinococcus granulosus hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Brugia malayi neuropeptide F receptor 0.0063 0.036 0.0525
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0023 0.0023
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.067 0.0956
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0064
Schistosoma mansoni myosin xvIII 0.0063 0.036 0.0378
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0058 0.0058
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.001 0.000000000050372 0.000000000073394
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Schistosoma mansoni hypothetical protein 0.0014 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0239 0.0348
Schistosoma mansoni carbonic anhydrase-related 0.0447 0.2984 0.3128
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0042 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0069
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0018 0.0027
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0183 0.0266
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0206 0.0216
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0058 0.0017
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0051 0.0172
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0209 0.0219
Brugia malayi Dopamine receptor protein 1 0.0063 0.036 0.0525
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.001 0.000000000050372 0.000000000052807
Schistosoma mansoni hypothetical protein 0.0014 0.0027 0.0028
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0025
Schistosoma mansoni lamin 0.0027 0.0114 0.012
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0051 0.0075
Echinococcus multilocularis lysine specific demethylase 5A 0.0032 0.0149 0.0216
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0043 0.0043
Plasmodium falciparum carbonic anhydrase 0.0447 0.2984 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0138 0.0464
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0023 0.0024
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0025
Schistosoma mansoni hypothetical protein 0.0014 0.0027 0.0028
Brugia malayi ORL1-like opioid receptor 0.0063 0.036 0.0525
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0061 0.0089
Echinococcus multilocularis Chromobox protein 3 0.001 0.0000000085911 0.000000012517
Brugia malayi Flap endonuclease-1 0.0024 0.0091 0.0133
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.008 0.0117
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0128
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0061 0.0089
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0027 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0525
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0166 0.0166
Schistosoma mansoni cpg binding protein 0.0031 0.0142 0.0149
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0012 0.0017
Schistosoma mansoni biogenic amine (5HT) receptor 0.0063 0.036 0.0378
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0063 0.036 0.1342
Schistosoma mansoni growth hormone secretagogue receptor 0.0063 0.036 0.0378
Onchocerca volvulus 0.0063 0.036 0.1342
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0676 0.0953
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0061 0.0089
Schistosoma mansoni flap endonuclease-1 0.0021 0.0075 0.0079
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0131 0.0438
Brugia malayi intermediate filament protein 0.0027 0.0114 0.0167
Entamoeba histolytica Flap nuclease, putative 0.0024 0.0091 0.0095
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0676 0.0709
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0061 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0525
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.001 0.0015
Echinococcus multilocularis G-protein coupled receptor, putative 0.0063 0.036 0.0525
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0027 0.011 0.0116
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0051 0.0075
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0014 0.0027 0.004
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0029 0.0129 0.5086
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0041 0.0207 0.0301
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0254 0.037
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus multilocularis carbonic anhydrase 0.0447 0.2984 0.4348
Plasmodium falciparum thioredoxin reductase 0.0048 0.0254 0.0851
Echinococcus multilocularis neuropeptide receptor 0.0063 0.036 0.0525
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus allatostatin A receptor 0.0063 0.036 0.0525
Brugia malayi hypothetical protein 0.0023 0.0088 0.0128
Schistosoma mansoni hypothetical protein 0.0027 0.011 0.0116
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0042 0.164
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0024 0.0091 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.1475 1 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0063 0.036 0.0525
Toxoplasma gondii thioredoxin reductase 0.0048 0.0254 0.0851
Loa Loa (eye worm) hypothetical protein 0.004 0.0205 0.0298
Trichomonas vaginalis chromobox protein, putative 0.0063 0.0362 0.0362
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0209 0.0304
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0244 0.0356
Onchocerca volvulus 0.0028 0.012 0.0445
Schistosoma mansoni DNA helicase recq1 0.0018 0.0051 0.0054
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0061 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.0378
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0089
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.4671 0.4896
Echinococcus granulosus serotonin receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0254 0.037
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0086 0.009
Loa Loa (eye worm) melatonin receptor type 1A 0.0063 0.036 0.0525
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0087 0.0092
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0447 0.2984 0.4348
Trichomonas vaginalis chromobox protein, putative 0.0063 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus multilocularis expressed protein 0.0376 0.2494 0.3633
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0063 0.036 0.0525
Echinococcus multilocularis allatostatin A receptor 0.0063 0.036 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.0378
Schistosoma mansoni hypothetical protein 0.0019 0.0057 0.006
Schistosoma mansoni jumonji domain containing protein 0.0069 0.0401 0.042
Loa Loa (eye worm) acetyltransferase 0.0134 0.0845 0.1232
Brugia malayi neuropeptide F receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0114 0.0167
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0061 0.0089
Echinococcus multilocularis PHD finger protein rhinoceros 0.0027 0.011 0.0161
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0063 0.036 0.0525
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.036 0.0525
Schistosoma mansoni chromodomain helicase DNA binding protein 0.001 0.000000000050372 0.000000000052807
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0525
Entamoeba histolytica carbonic anhydrase, putative 0.1407 0.9539 1
Echinococcus granulosus peregrin 0.0032 0.0147 0.0215
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.001 0.0015
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0171 0.018
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1016 0.6863 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0042 0.014
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.0676 0.0637
Echinococcus multilocularis orexin receptor type 2 0.0063 0.036 0.0525
Brugia malayi MH2 domain containing protein 0.0109 0.0672 0.0979
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0341 0.0357
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0023 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0061
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0042 0.0025
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0063 0.036 0.0525
Echinococcus multilocularis g protein coupled receptor 0.0063 0.036 0.0525
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0002 0.0004
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0063 0.036 0.0378
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.036 0.0525
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.001 0.000000000050372 0.000000000052807
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0069
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0087 0.0066
Echinococcus granulosus fmrfamide receptor 0.0063 0.036 0.0525
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0209 0.8227
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0676 0.0676
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0063 0.036 0.0525
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0254 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.0676 1
Loa Loa (eye worm) phosphofructokinase 0.0109 0.0676 0.0985
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0014 0.0027 0.004
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Trypanosoma brucei PAB1-binding protein , putative 0.0023 0.0086 0.009
Brugia malayi 6-phosphofructokinase 0.0109 0.0676 0.0985
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0002 0.0003
Echinococcus multilocularis cpg binding protein 0.0031 0.0142 0.0207
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.036 0.0378
Onchocerca volvulus 0.0023 0.0088 0.0328
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0525
Schistosoma mansoni hypothetical protein 0.0014 0.0027 0.0028
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0063 0.036 0.0525
Echinococcus multilocularis Protein lozenge 0.0051 0.0275 0.04
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0753 0.1082
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0334 0.112
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0676 0.0676
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0058 0.0085
Echinococcus multilocularis g-protein coupled receptor 0.0063 0.036 0.0525
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0035 0.0037
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0063 0.036 0.0525
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0066 0.0096
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0044
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) RecQ helicase 0.0043 0.0225 0.0328
Loa Loa (eye worm) hypothetical protein 0.0044 0.0227 0.0331
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0089
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0131 0.0438
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0114 0.0167
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0087 0.0523 0.0762
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1016 0.6863 1
Onchocerca volvulus 0.0063 0.036 0.1342
Brugia malayi glutathione reductase 0.0048 0.0254 0.037
Schistosoma mansoni hypothetical protein 0.0397 0.2642 0.277
Brugia malayi CHD4 protein 0.0014 0.0023 0.0033
Loa Loa (eye worm) PHD-finger family protein 0.0027 0.011 0.0161
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0058 0.0061
Onchocerca volvulus 0.0063 0.036 0.1342
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0676 0.0709
Echinococcus granulosus histone acetyltransferase KAT2B 0.0128 0.0805 0.1173
Schistosoma mansoni amine GPCR 0.0063 0.036 0.0378
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0051 0.0075
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0114 0.0167
Schistosoma mansoni ap endonuclease 0.0019 0.0058 0.0061
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.0378
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.036 0.0525
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.0676 0.0985
Brugia malayi hypothetical protein 0.0015 0.003 0.0044
Brugia malayi hypothetical protein 0.0122 0.0765 0.1115
Brugia malayi acetyltransferase, GNAT family protein 0.0134 0.0845 0.1232
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.1475 1 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0045 0.0239 0.0348
Brugia malayi follicle stimulating hormone receptor 0.0295 0.1941 0.2828
Echinococcus granulosus bloom syndrome protein 0.0043 0.0225 0.0328
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.036 0.0525
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0036 0.0172 0.0641
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.036 0.0378
Loa Loa (eye worm) hypothetical protein 0.0426 0.284 0.4137
Brugia malayi Pre-SET motif family protein 0.021 0.1363 0.1986
Onchocerca volvulus 0.0063 0.036 0.1342
Echinococcus multilocularis carbonic anhydrase 0.0447 0.2984 0.4348
Schistosoma mansoni opsin-like receptor 0.0063 0.036 0.0378
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.036 0.0525
Echinococcus granulosus g protein coupled receptor 0.0063 0.036 0.0525
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.036 0.0525
Brugia malayi PHD-finger family protein 0.0028 0.0117 0.017
Entamoeba histolytica hypothetical protein 0.0019 0.0061 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0525
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0225 0.0225
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0024 0.0091 0.007
Onchocerca volvulus 0.0063 0.036 0.1342
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0171 0.025
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0131 0.0438
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.036 0.0525
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0254 0.0336
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0025
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0064
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0209 0.0209
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.036 0.0525
Brugia malayi SET domain containing protein 0.0012 0.0012 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0206 0.0216
Echinococcus multilocularis neuropeptide receptor A26 0.0482 0.3222 0.4694
Echinococcus granulosus dro:myosuppressin receptor 0.0063 0.036 0.0525
Onchocerca volvulus 0.0063 0.036 0.1342
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.001 0.000000000050372 0.000000000073394
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0042 0.0061
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0058 0.1275
Brugia malayi GnHR receptor homolog 0.0063 0.036 0.0525
Schistosoma mansoni neuropeptide f receptor 76f 0.0063 0.036 0.0378
Echinococcus granulosus 7TM GPCR rhodopsin 0.0063 0.036 0.0525
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0127 0.0425
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0064
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0061 0.0089
Brugia malayi hypothetical protein 0.0112 0.0691 0.1007
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0131 0.5152
Plasmodium vivax hypothetical protein, conserved 0.0027 0.011 0.4348
Loa Loa (eye worm) hypothetical protein 0.0027 0.0114 0.0167
Schistosoma mansoni bromodomain containing protein 0.0062 0.0356 0.0373
Echinococcus multilocularis neuropeptide s receptor 0.0482 0.3222 0.4694
Onchocerca volvulus 0.0041 0.0207 0.077
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0061 0.0089
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Loa Loa (eye worm) heterochromatin protein 1 0.0063 0.0362 0.0528
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.036 0.0525
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0061 0.0089
Plasmodium falciparum thioredoxin reductase 0.0016 0.0042 0.014
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.067 0.0956
Brugia malayi Bromodomain containing protein 0.0038 0.0189 0.0276
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0244 0.0256
Brugia malayi G protein-coupled receptor 0.0063 0.036 0.0525
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0063 0.036 0.0525
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0131 0.0137
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0061 0.0089
Plasmodium falciparum histone acetyltransferase GCN5 0.0036 0.0172 0.0577
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0025
Brugia malayi jmjC domain containing protein 0.0087 0.0523 0.0762
Echinococcus multilocularis peregrin 0.0032 0.0147 0.0215
Echinococcus granulosus orexin receptor type 2 0.0063 0.036 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.0378
Leishmania major C-8 sterol isomerase-like protein 0.0371 0.2459 0.2559
Schistosoma mansoni carbonic anhydrase-related 0.0447 0.2984 0.3128
Brugia malayi G-protein coupled receptor 0.0063 0.036 0.0525
Echinococcus granulosus carbonic anhydrase 0.0447 0.2984 0.4348
Echinococcus multilocularis GPCR, family 2 0.0014 0.0027 0.004
Loa Loa (eye worm) hypothetical protein 0.0404 0.2684 0.3911
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0131 0.0131
Plasmodium vivax glutathione reductase, putative 0.0048 0.0254 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0525
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0131 0.0131
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0131 0.0131
Onchocerca volvulus Alhambra homolog 0.0027 0.011 0.0411
Echinococcus multilocularis musashi 0.0027 0.0114 0.0167
Trypanosoma brucei trypanothione reductase 0.0048 0.0254 0.0336
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0447 0.2984 0.4348
Echinococcus multilocularis lamin dm0 0.0027 0.0114 0.0167
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.0676 0.0006
Brugia malayi Tachykinin-like peptides receptor 99D 0.0063 0.036 0.0525
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0043 0.0043
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0058 0.0262
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0061 0.0089
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1016 0.6863 0.7195
Echinococcus granulosus dnaJ subfamily B 0.0397 0.2642 0.385
Leishmania major trypanothione reductase 0.0048 0.0254 0.0241
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0063 0.036 0.0378
Brugia malayi PXA domain containing protein 0.0019 0.0061 0.0089
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0138 0.0145
Loa Loa (eye worm) hypothetical protein 0.0404 0.2684 0.3911
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.036 0.0525
Brugia malayi Thioredoxin reductase 0.0048 0.0254 0.037
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0041 0.0207 0.0301
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0022
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0042 0.0042
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.067 0.0956
Toxoplasma gondii exonuclease III APE 0.0019 0.0058 0.0195
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0061 0.0089
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0676 0.0985
Brugia malayi PXA domain containing protein 0.0019 0.0061 0.0089
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0061 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.0378
Brugia malayi RE15519p 0.0063 0.036 0.0525
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0042 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0002 0.0003
Echinococcus granulosus neuropeptide receptor 0.0063 0.036 0.0525
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Brugia malayi chromobox protein homolog 3 0.0036 0.0172 0.0251
Schistosoma mansoni cpg binding protein 0.0028 0.012 0.0125
Echinococcus multilocularis chromobox protein 1 0.0063 0.0362 0.0528
Echinococcus granulosus Chromo domain 0.001 0.000000000050372 0.000000000073394
Echinococcus granulosus carbonic anhydrase 0.0447 0.2984 0.4348
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.001 0.000000000050372 0.00000000016881
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0041 0.0207 0.0301
Echinococcus multilocularis zinc finger protein 0.0023 0.0084 0.0122
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Brugia malayi hypothetical protein 0.0063 0.036 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0064 0.0369 0.0538
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0254 0.0323
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0676 0.0709
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0058 0.0085
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0131 0.0438
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0128
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0018
Echinococcus multilocularis g protein coupled receptor 0.0063 0.036 0.0525
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0063 0.036 0.0525
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.001 0.000000000050372 0.000000000052807
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.001 0.000000000050372 0.00000000016881
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0089
Onchocerca volvulus Huntingtin homolog 0.0112 0.0691 0.2575
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.036 0.0525
Brugia malayi putative neuropeptide receptor 0.0063 0.036 0.0525
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0225 0.0328
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.036 0.0525
Trichomonas vaginalis chromobox protein, putative 0.0038 0.019 0.019
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0042 0.0025
Brugia malayi Serotonin receptor 0.0063 0.036 0.0525
Brugia malayi Bromodomain containing protein 0.0073 0.0429 0.0624
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0043 0.0043
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.001 0.000000000050372 0.000000000052807
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.067 0.0956
Loa Loa (eye worm) hypothetical protein 0.0127 0.0798 0.1162
Loa Loa (eye worm) jmjC domain-containing protein 0.0055 0.0304 0.0442
Onchocerca volvulus Huntingtin homolog 0.0112 0.0691 0.2575
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0753 0.0093
Schistosoma mansoni hypothetical protein 0.0154 0.0983 0.1031
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0024 0.0091 0.0098
Schistosoma mansoni alpha-1 adrenergic receptor 0.0063 0.036 0.0378
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0064
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0061 0.0064
Plasmodium falciparum glutathione reductase 0.0048 0.0254 0.0851
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0063 0.036 0.0525
Schistosoma mansoni hypothetical protein 0.0031 0.0141 0.0148
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0171 0.025
Brugia malayi sulfakinin receptor protein 0.0063 0.036 0.0525
Echinococcus multilocularis flap endonuclease 1 0.0024 0.0091 0.0133
Echinococcus multilocularis neuropeptide FF receptor 2 0.0063 0.036 0.0525
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.002 0.002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0043 0.0045
Schistosoma mansoni carbonic anhydrase 0.1407 0.9539 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.000000000050372 0.000000000050372
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0063 0.036 0.0378
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0089
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0061 0.0089
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0676 0.0709
Echinococcus multilocularis serotonin receptor 0.0426 0.284 0.4137
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus somatostatin receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0022
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.1407 0.9539 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0063 0.036 0.0525
Echinococcus granulosus neuropeptide receptor 0.0063 0.036 0.0525
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0209 0.07
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0002 0.0004
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0061 0.0089
Loa Loa (eye worm) runx1 0.0051 0.0275 0.04
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0063 0.036 0.0378
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Schistosoma mansoni amine GPCR 0.0063 0.036 0.0378
Echinococcus granulosus lamin dm0 0.0027 0.0114 0.0167
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0058 0.005
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0042 0.014
Toxoplasma gondii LsmAD domain-containing protein 0.0023 0.0086 0.0288
Echinococcus granulosus zinc finger protein 0.0023 0.0084 0.0122
Loa Loa (eye worm) hypothetical protein 0.0371 0.2459 0.3583
Onchocerca volvulus 0.0027 0.0114 0.0426
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus carbonic anhydrase 0.0447 0.2984 0.4348
Brugia malayi PHD-finger family protein 0.0027 0.011 0.0161
Loa Loa (eye worm) hypothetical protein 0.0031 0.0141 0.0206
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0087 0.0523 0.0762
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0061
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0023 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0063 0.036 0.0378
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0025
Onchocerca volvulus 0.0063 0.036 0.1342
Echinococcus granulosus PHD finger protein rhinoceros 0.0027 0.011 0.0161
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0035 0.0037
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Schistosoma mansoni amine GPCR 0.0063 0.036 0.0378
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0676 0.0676
Echinococcus granulosus peptide allatostatin:somatostatin 0.0063 0.036 0.0525
Echinococcus multilocularis carbonic anhydrase 0.0447 0.2984 0.4348
Schistosoma mansoni DNA helicase recq5 0.0018 0.0051 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0525
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0183 0.0266
Brugia malayi AKH receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0058 0.0085
Brugia malayi PHD-finger family protein 0.0012 0.0011 0.0016
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0171 0.018
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.011 0.037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0043 0.0043
Onchocerca volvulus 0.0041 0.0207 0.077
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Onchocerca volvulus 0.0063 0.036 0.1342
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.0378
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0244 0.0256
Echinococcus granulosus chromobox protein 1 0.0063 0.0362 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.001 0.000000000050372 0.000000000073394
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.0676 0.0685
Schistosoma mansoni chromobox protein 0.0063 0.0362 0.038
Plasmodium falciparum glutathione reductase 0.0016 0.0042 0.014
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0676 0.0953
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0525
Echinococcus granulosus g protein coupled receptor 0.0063 0.036 0.0525
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0131 0.0131
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0042 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0025
Brugia malayi G protein-coupled receptor F59B2.13 0.0063 0.036 0.0525
Echinococcus multilocularis carbonic anhydrase II 0.1016 0.6863 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.012 0.0174
Onchocerca volvulus 0.0063 0.036 0.1342
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0041 0.0207 0.0301
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0061 0.0064
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0002 0.0004
Brugia malayi Heterochromatin protein 1 0.0063 0.0362 0.0528
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.1363 0.1986
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0028 0.012 0.0174
Brugia malayi Serotonin receptor 0.0063 0.036 0.0525
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0057 0.0084
Loa Loa (eye worm) hypothetical protein 0.0112 0.0691 0.1007
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0371 0.2459 0.3583
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0025
Onchocerca volvulus 0.0063 0.036 0.1342
Echinococcus multilocularis geminin 0.0154 0.0983 0.1432
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0209 0.07
Brugia malayi Dopamine receptor protein 2 0.0063 0.036 0.0525
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0061 0.0089
Loa Loa (eye worm) hypothetical protein 0.0447 0.2984 0.4348
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0063 0.036 0.0525
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0061 0.0089

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) Inhibition of CETP in human whole plasma ChEMBL. 18374566
IC50 (binding) 0 Inhibition of CETP in human whole plasma ChEMBL. 18374566
IC50 (binding) > 10 uM Inhibition of human CETP by scintillation proximity assay ChEMBL. 18374566
IC50 (binding) > 10 uM Inhibition of human CETP by scintillation proximity assay ChEMBL. 18374566

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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