Detailed information for compound 575714

Basic information

Technical information
  • TDR Targets ID: 575714
  • Name: (2S)-2-(hydroxyamino)-3-(4-hydroxyphenyl)prop anoic acid
  • MW: 197.188 | Formula: C9H11NO4
  • H donors: 4 H acceptors: 4 LogP: -1.74 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: ON[C@H](C(=O)O)Cc1ccc(cc1)O
  • InChi: 1S/C9H11NO4/c11-7-3-1-6(2-4-7)5-8(10-14)9(12)13/h1-4,8,10-11,14H,5H2,(H,12,13)/t8-/m0/s1
  • InChiKey: CNIUEVQJABPUIJ-QMMMGPOBSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-(hydroxyamino)-3-(4-hydroxyphenyl)propionic acid
  • N-hydroxytyrosine
  • 64448-49-3
  • CHEBI:28089
  • C03004
  • N-Hydroxy-L-tyrosine
  • L-Tyrosine, N-hydroxy-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) DR-78 0.0014 0.0094 0.0131
Schistosoma mansoni ran 0.0022 0.0184 0.0351
Onchocerca volvulus 0.016 0.1856 0.4629
Brugia malayi gonadotropin-releasing hormone receptor 2 0.001 0.0035 0.0035
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.068 0.1338
Schistosoma mansoni neutral sphingomyelinase 0.0008 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0451
Loa Loa (eye worm) hypothetical protein 0.0053 0.0564 0.09
Echinococcus multilocularis beta catenin 0.0101 0.1151 0.1144
Brugia malayi hypothetical protein 0.0014 0.0094 0.0131
Echinococcus granulosus sex peptide receptor 0.001 0.0035 0.0047
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0163 0.0245
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0289 0.0561
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0035 0.0054
Schistosoma mansoni lamin 0.0081 0.09 0.1777
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0172 0.2066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0035 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0289 0.0451
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0289 0.0451
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus multilocularis g protein coupled receptor 0.001 0.0035 0.0027
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0564 1
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0008 0.0013 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000010079 0.00000000016447
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0094 0.0131
Schistosoma mansoni alpha-1 adrenergic receptor 0.001 0.0035 0.0054
Brugia malayi G protein-coupled receptor 0.001 0.0035 0.0035
Entamoeba histolytica hypothetical protein 0.0072 0.0796 1
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0289 0.0451
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0532 0.9432
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Schistosoma mansoni Smad4 0.0008 0.0019 0.0022
Brugia malayi AKH receptor 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0451
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0289 0.0494
Schistosoma mansoni hypothetical protein 0.0334 0.3971 0.7897
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0035 0.0054
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0028 0.0024
Brugia malayi tailless protein 0.0014 0.0094 0.0131
Echinococcus multilocularis lamin dm0 0.0081 0.09 0.0893
Schistosoma mansoni hypothetical protein 0.0064 0.0697 0.1372
Brugia malayi nuclear receptor RXR 0.0014 0.0094 0.0131
Echinococcus multilocularis g protein coupled receptor 0.001 0.0035 0.0027
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0289 0.0451
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0.0035 0.0054
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.3993 0.6516
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0071 0.0782 0.1257
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0377 0.0369
Echinococcus granulosus g protein coupled receptor 0.001 0.0035 0.0047
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.059
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0697 0.0689
Echinococcus granulosus neuropeptide FF receptor 2 0.001 0.0035 0.0047
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0532 0.8874
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0387 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0289 0.0451
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0172 0.2028
Echinococcus granulosus alpha 1A adrenergic receptor 0.001 0.0035 0.0047
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0184 0.0176
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0163 0.0272
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0008 0.0013 0.0006
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0172 0.2715
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0202 0.2377 0.3866
Schistosoma mansoni smad1 5 8 and 0.0008 0.0019 0.0022
Schistosoma mansoni biogenic amine receptor 0.001 0.0035 0.0054
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0194 0.0326
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0035 0.0027
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0115 0.0107
Onchocerca volvulus 0.001 0.0035 0.0054
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000010079 0.00000000016447
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.0035 0.0027
Echinococcus granulosus neuropeptide receptor A26 0.0477 0.5709 1
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0064 0.0697 0.1117
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0172 0.228
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0172 0.228
Schistosoma mansoni smad1 5 8 and 0.0008 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus granulosus bloom syndrome protein 0.002 0.0163 0.0272
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0289 0.0561
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0211 0.2834
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0172 0.2715
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.001 0.0035 0.0035
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0106 0.0098
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus multilocularis alpha 1A adrenergic receptor 0.001 0.0035 0.0027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0289 0.0451
Loa Loa (eye worm) hypothetical protein 0.0053 0.0564 0.09
Echinococcus granulosus neuropeptide Y receptor 0.001 0.0035 0.0047
Echinococcus granulosus neutral sphingomyelinase 0.0008 0.0013 0.001
Brugia malayi Dopamine receptor protein 2 0.001 0.0035 0.0035
Schistosoma mansoni smad 0.0008 0.0019 0.0022
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0163 0.2151
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000010079 0.00000000016447
Entamoeba histolytica recQ family DNA helicase 0.001 0.0043 0.0383
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.001 0.0035 0.0035
Echinococcus multilocularis bloom syndrome protein 0.002 0.0163 0.0155
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0163 0.0245
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0184 0.2447
Onchocerca volvulus 0.0021 0.0172 0.0399
Schistosoma mansoni neuropeptide f receptor 76f 0.001 0.0035 0.0054
Schistosoma mansoni amine GPCR 0.001 0.0035 0.0054
Brugia malayi putative neuropeptide receptor NPR1 0.001 0.0035 0.0035
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0106 0.1685
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0035 0.0054
Onchocerca volvulus 0.0071 0.0782 0.1931
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0387 0.4777
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0782 1
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0013 0.0022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.0035 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0035 0.0047
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.071 1
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0115 0.0166
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0172 0.2066
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0106 0.0152
Echinococcus granulosus orexin receptor type 2 0.001 0.0035 0.0047
Echinococcus multilocularis g protein coupled receptor 0.001 0.0035 0.0027
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0279 0.4539
Brugia malayi nuclear hormone receptor 0.0014 0.0094 0.0131
Loa Loa (eye worm) hypothetical protein 0.0053 0.0564 0.09
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.001 0.0035 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0528 0.6702
Trichomonas vaginalis Phospholipase C precursor, putative 0.0008 0.0013 0.0022
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0008 0.0013 0.001
Schistosoma mansoni peptide (allatostatin)-like receptor 0.001 0.0035 0.0054
Echinococcus granulosus geminin 0.0334 0.3971 0.6952
Echinococcus multilocularis snurportin 1 0.0317 0.3763 0.3758
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0106 0.1331
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0094 0.015
Loa Loa (eye worm) hypothetical protein 0.0051 0.0532 0.0849
Brugia malayi Melatonin receptor type 1A 0.001 0.0035 0.0035
Leishmania major hypothetical protein, conserved 0.0051 0.0532 0.6754
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0049
Loa Loa (eye worm) hypothetical protein 0.0039 0.0392 0.0619
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0172 0.2066
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.001 0.0035 0.0035
Echinococcus multilocularis protein pangolin J 0.0068 0.0742 0.0735
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0289 0.0451
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0115 0.0187
Echinococcus multilocularis dro:myosuppressin receptor 0.001 0.0035 0.0027
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.047 0.0463
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0172 0.2066
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0172 0.026
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0106 0.1685
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0377 0.0647
Schistosoma mansoni cpg binding protein 0.0031 0.0298 0.0578
Echinococcus multilocularis tachykinin peptides receptor 99D 0.001 0.0035 0.0027
Leishmania major importin beta-1 subunit, putative 0.0024 0.0211 0.2568
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0035 0.0047
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0039 0.0431
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.0035 0.0035
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0172 0.2066
Echinococcus multilocularis g-protein coupled receptor 0.001 0.0035 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0035 0.0047
Plasmodium vivax importin-beta 2, putative 0.003 0.0279 0.4825
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0289 0.0451
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0106 0.0098
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.001 0.0039 0.0458
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0106 0.1331
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0387 0.5371
Brugia malayi hypothetical protein 0.0051 0.0532 0.0849
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0172 0.2066
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0289 0.0282
Toxoplasma gondii exonuclease III APE 0.0039 0.0387 0.6395
Brugia malayi ecdysone receptor 0.0014 0.0094 0.0131
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0289 0.0494
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0094 0.0131
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0172 0.0281
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0106 0.1331
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0115 0.0213
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0094 0.0202
Schistosoma mansoni hypothetical protein 0.001 0.0035 0.0054
Loa Loa (eye worm) hypothetical protein 0.0079 0.0882 0.142
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0035 0.0047
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.003 0.0038
Echinococcus granulosus G protein coupled receptor 139 0.001 0.0035 0.0047
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0094 0.015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0289 0.0451
Schistosoma mansoni hypothetical protein 0.0247 0.2918 0.5798
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.1391 0.2253
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0163 0.0245
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.071 0.0703
Schistosoma mansoni carbon catabolite repressor protein 0.0008 0.0013 0.0011
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.071 0.9063
Brugia malayi follicle stimulating hormone receptor 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0202 0.2377 0.3866
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0782 1
Echinococcus granulosus T cell transcription factor 4 long C terminal 0.0068 0.0742 0.1288
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0289 0.0561
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0163 0.0266
Loa Loa (eye worm) hypothetical protein 0.0016 0.0115 0.0166
Schistosoma mansoni nuclear receptor 0.0014 0.0094 0.0171
Entamoeba histolytica hypothetical protein 0.0024 0.0211 0.2521
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0796 0.1383
Loa Loa (eye worm) hypothetical protein 0.003 0.0279 0.0434
Schistosoma mansoni importin beta-1 0.003 0.0279 0.054
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0289 0.0561
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0289 0.0494
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.0035 0.0027
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0094 0.0131
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0184 0.3097
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.1391 0.2253
Loa Loa (eye worm) TYRA-2 protein 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0387 0.038
Loa Loa (eye worm) hypothetical protein 0.0071 0.0782 0.1257
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.047 0.0747
Echinococcus multilocularis fmrfamide receptor 0.001 0.0035 0.0027
Brugia malayi MH1 domain containing protein 0.0008 0.0019 0.0009
Brugia malayi MH2 domain containing protein 0.0008 0.0019 0.0009
Echinococcus granulosus g-protein coupled receptor 0.001 0.0035 0.0047
Echinococcus granulosus 7TM GPCR rhodopsin 0.001 0.0035 0.0047
Loa Loa (eye worm) RecQ helicase 0.002 0.0163 0.0245
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0163 0.0155
Schistosoma mansoni hypothetical protein 0.001 0.0035 0.0054
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0387 0.0666
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0387 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.001 0.0035 0.0027
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0184 0.2447
Schistosoma mansoni amine GPCR 0.001 0.0035 0.0054
Echinococcus multilocularis neuropeptide FF receptor 2 0.001 0.0035 0.0027
Onchocerca volvulus Glucosylceramidase homolog 0.0336 0.3993 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0172 0.2066
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0163 0.2562
Loa Loa (eye worm) hypothetical protein 0.0016 0.0115 0.0166
Onchocerca volvulus 0.001 0.0035 0.0054
Brugia malayi G-protein coupled receptor 0.001 0.0035 0.0035
Brugia malayi MH1 domain containing protein 0.0008 0.0019 0.0009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.047 0.0747
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0043 0.0512
Loa Loa (eye worm) histone methyltransferase 0.0009 0.003 0.0027
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0115 0.0213
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0035 0.0027
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0094 0.015
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0289 0.0561
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0094 0.0086
Brugia malayi conserved hypotetical protein 0.0014 0.0094 0.0131
Echinococcus granulosus GPCR family 2 0.0064 0.0697 0.1208
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0094 0.0202
Loa Loa (eye worm) hypothetical protein 0.0081 0.09 0.145
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0289 0.0282
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0289 0.0494
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0172 0.2066
Echinococcus granulosus tachykinin peptides receptor 99D 0.001 0.0035 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0035 0.0054
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0289 0.0282
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0289 0.0282
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0782 0.9815
Brugia malayi Tachykinin-like peptides receptor 99D 0.001 0.0035 0.0035
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000010079 0.00000000016447
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0094 0.0171
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0172 0.026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.047 0.0811
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.3993 0.6516
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0392 0.0674
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.001 0.0035 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0035 0.0027
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0172 0.2715
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0094 0.015
Treponema pallidum ATP-dependent DNA helicase 0.001 0.0043 0.0801
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0392 0.0385
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.001 0.0035 0.0054
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0184 0.2914
Brugia malayi Smad1 0.0008 0.0019 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0782 0.1257
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0289 0.0561
Schistosoma mansoni neuropeptide receptor 0.0162 0.1884 0.3738
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000010079 0.00000000016447
Brugia malayi neuropeptide F receptor 0.001 0.0035 0.0035
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0172 0.026
Schistosoma mansoni adenoreceptor 0.001 0.0035 0.0054
Echinococcus multilocularis orexin receptor type 2 0.001 0.0035 0.0027
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0782 1
Brugia malayi hypothetical protein 0.0014 0.0094 0.0131
Schistosoma mansoni opsin-like receptor 0.001 0.0035 0.0054
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0289 0.0451
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0697 0.1117
Schistosoma mansoni cpg binding protein 0.003 0.0277 0.0537
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0138 0.1599 0.3171
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0532 0.7452
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0289 0.0494
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.001 0.0035 0.0035
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0387 0.4868
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.071 0.1139
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0163 0.4005
Onchocerca volvulus 0.001 0.0035 0.0054
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0697 0.1117
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus granulosus hypothetical protein 0.001 0.0035 0.0047
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0115 0.0166
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0289 0.0282
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0035 0.0027
Brugia malayi putative neuropeptide receptor 0.001 0.0035 0.0035
Brugia malayi Serotonin receptor 0.001 0.0035 0.0035
Mycobacterium ulcerans hypothetical protein 0.0071 0.0782 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0451
Schistosoma mansoni hypothetical protein 0.0064 0.0697 0.1372
Echinococcus multilocularis cpg binding protein 0.0031 0.0298 0.029
Schistosoma mansoni neuropeptide receptor 0.001 0.0035 0.0054
Schistosoma mansoni hypothetical protein 0.0064 0.0697 0.1372
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0094 0.0086
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0289 0.0451
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.001 0.0035 0.0027
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0387 0.4868
Loa Loa (eye worm) follicle stimulating hormone receptor 0.001 0.0035 0.0035
Echinococcus granulosus neuropeptide receptor 0.001 0.0035 0.0047
Schistosoma mansoni amine GPCR 0.001 0.0035 0.0054
Loa Loa (eye worm) hypothetical protein 0.0053 0.0564 0.09
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0011 0.0049 0.0506
Brugia malayi Dopamine receptor 0.001 0.0035 0.0035
Echinococcus granulosus smad 0.0008 0.0019 0.002
Echinococcus multilocularis neuropeptide receptor A26 0.0477 0.5709 0.5705
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0106 0.0172
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0172 0.2886
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.09 0.145
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0387 0.5371
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0782 0.9815
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Schistosoma mansoni DNA helicase recq1 0.002 0.0163 0.0309
Brugia malayi nuclear receptor NHR-67 0.0014 0.0094 0.0131
Echinococcus multilocularis Smad4 0.0008 0.0019 0.0011
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0172 0.2066
Brugia malayi hypothetical protein 0.0016 0.0115 0.0166
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0019 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0035 0.0027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.0035 0.0027
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0094 0.0086
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0035 0.0027
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0782 0.1257
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0106 0.1206
Onchocerca volvulus 0.001 0.0035 0.0054
Brugia malayi nuclear receptor RXR 0.0016 0.0115 0.0166
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0035 0.0047
Loa Loa (eye worm) hypothetical protein 0.0071 0.0782 0.1257
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0172 0.228
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0289 0.0282
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0184 0.2447
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0013 0.0006
Schistosoma mansoni coup transcription factor 0.0031 0.0289 0.0561
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0211 0.0344
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0289 0.0451
Loa Loa (eye worm) hypothetical protein 0.0138 0.1599 0.2594
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0289 0.0561
Brugia malayi Calcitonin receptor-like protein seb-1 0.0202 0.2377 0.3866
Brugia malayi RNA, U transporter 1 0.0084 0.0943 0.152
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0289 0.0494
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus granulosus neuropeptide Y receptor 0.001 0.0035 0.0047
Echinococcus granulosus snurportin 1 0.0317 0.3763 0.6587
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.059
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0511 0.6128 1
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0172 0.0288
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0008 0.0013 0.0022
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0387 0.0612
Echinococcus granulosus serotonin receptor 0.001 0.0035 0.0047
Schistosoma mansoni beta-catenin 0.0101 0.1151 0.2277
Onchocerca volvulus Cirhin homolog 0.0101 0.1143 0.2837
Loa Loa (eye worm) HMG box family protein 0.0068 0.0742 0.1192
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0035 0.0047
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0782 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0184 0.4556
Schistosoma mansoni nocturnin 0.0008 0.0013 0.0011
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0697 0.1208
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.0035 0.0047
Brugia malayi isocitrate dehydrogenase 0.0015 0.0106 0.0152
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0697 0.1117
Schistosoma mansoni neuropeptide F-like receptor 0.001 0.0035 0.0054
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0094 0.0171
Brugia malayi G protein-coupled receptor F59B2.13 0.001 0.0035 0.0035
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0035 0.0047
Schistosoma mansoni hypothetical protein 0.001 0.0035 0.0054
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0532 0.9432
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Onchocerca volvulus 0.0081 0.09 0.2227
Brugia malayi intermediate filament protein 0.0081 0.09 0.145
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0008 0.0013 0.001
Plasmodium falciparum importin beta, putative 0.003 0.0279 0.4825
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Schistosoma mansoni neuropeptide F-like receptor 0.001 0.0035 0.0054
Echinococcus granulosus g protein coupled receptor 0.001 0.0035 0.0047
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.001 0.0035 0.0047
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0387 0.3531
Schistosoma mansoni ap endonuclease 0.0039 0.0387 0.0756
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Onchocerca volvulus 0.0031 0.0289 0.0694
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.001 0.0035 0.0035
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0782 1
Echinococcus multilocularis traf and tnf receptor associated protein 0.0008 0.0013 0.0006
Brugia malayi hypothetical protein 0.0016 0.0115 0.0166
Trichomonas vaginalis glucosylceramidase, putative 0.0511 0.6128 1
Echinococcus granulosus g protein coupled receptor 0.001 0.0035 0.0047
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0172 0.228
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.001 0.0035 0.0027
Leishmania major GTP-binding protein, putative 0.0022 0.0184 0.2218
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.047 0.0922
Brugia malayi CXXC zinc finger family protein 0.003 0.0277 0.0432
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0035 0.0047
Echinococcus granulosus somatostatin receptor 0.001 0.0035 0.0047
Onchocerca volvulus 0.001 0.0035 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0289 0.0451
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0043 0.043
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0317 0.3763 0.6132
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0049
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0013 0.001
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0008 0.0013 0.0022
Brugia malayi MH2 domain containing protein 0.0121 0.1391 0.2253
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0172 0.2066
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.0035 0.0054
Schistosoma mansoni opsin-like receptor 0.001 0.0035 0.0054
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0094 0.0171
Loa Loa (eye worm) melatonin receptor type 1A 0.001 0.0035 0.0035
Echinococcus multilocularis serotonin receptor 0.001 0.0035 0.0027
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0106 0.0098
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0094 0.0086
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0387 0.0612
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0172 0.2066
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0564 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus granulosus neuropeptides capa receptor 0.001 0.0035 0.0047
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0289 0.0494
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0019 0.0011
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0106 0.0098
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0094 0.0131
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0782 0.9815
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0289 0.0282
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0532 0.7452
Loa Loa (eye worm) hypothetical protein 0.002 0.0163 0.0245
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.0035 0.0047
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.0035 0.0035
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0008 0.0013 0.0011
Onchocerca volvulus 0.001 0.0035 0.0054
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0008 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Brugia malayi hypothetical protein 0.0033 0.0315 0.0493
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.001 0.0035 0.0054
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0.0035 0.0054
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.4212 0.6874
Onchocerca volvulus 0.0081 0.09 0.2227
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus multilocularis geminin 0.0334 0.3971 0.3967
Echinococcus granulosus thyrotropin releasing hormone receptor 0.001 0.0035 0.0047
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0451
Brugia malayi nuclear receptor NHR-88 0.0031 0.0289 0.0451
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.0035 0.0047
Entamoeba histolytica recQ family helicase, putative 0.001 0.0039 0.0322
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0564 0.6421
Onchocerca volvulus 0.001 0.0035 0.0054
Loa Loa (eye worm) hypothetical protein 0.0016 0.0115 0.0166
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0163 0.2562
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0172 0.026
Echinococcus granulosus beta catenin 0.0101 0.1151 0.2005
Onchocerca volvulus 0.001 0.0035 0.0054
Echinococcus granulosus importin subunit beta 1 0.003 0.0279 0.0475
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0782 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0094 0.0086
Echinococcus multilocularis musashi 0.0081 0.09 0.0893
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0289 0.0451
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0782 1
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.3993 0.6516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0035 0.0054
Echinococcus multilocularis sex peptide receptor 0.001 0.0035 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.047 0.0922
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.3993 0.6516
Loa Loa (eye worm) hypothetical protein 0.0021 0.0172 0.026
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.001 0.0035 0.0047
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0172 0.026
Onchocerca volvulus Neuropeptide F receptor homolog 0.001 0.0035 0.0054
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0094 0.0131
Schistosoma mansoni hypothetical protein 0.0023 0.0194 0.0371
Brugia malayi Serotonin/octopamine receptor family protein 7 0.001 0.0035 0.0035
Schistosoma mansoni cript-related 0.0008 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0697 0.1208
Trichomonas vaginalis glucosylceramidase, putative 0.0511 0.6128 1
Echinococcus multilocularis allatostatin A receptor 0.001 0.0035 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0511 0.6128 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0289 0.0561
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0094 0.0131
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0094 0.015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0035 0.0054
Echinococcus granulosus hypothetical protein 0.0314 0.3734 0.6536
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0106 0.0098
Brugia malayi GnHR receptor homolog 0.001 0.0035 0.0035
Echinococcus multilocularis neuropeptide receptor 0.001 0.0035 0.0027
Schistosoma mansoni amine GPCR 0.001 0.0035 0.0054
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0106 0.1585
Loa Loa (eye worm) HMP-2 protein 0.0101 0.1151 0.186
Schistosoma mansoni pangolin 0.0068 0.0742 0.1463
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0172 0.228
Onchocerca volvulus 0.0021 0.0172 0.0399
Brugia malayi neuropeptide F receptor 0.001 0.0035 0.0035
Echinococcus granulosus peptide allatostatin:somatostatin 0.001 0.0035 0.0047
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0106 0.0152
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.001 0.0035 0.0054
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0094 0.0086
Onchocerca volvulus 0.001 0.0035 0.0054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0528 0.6702
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.001 0.0035 0.0027
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0598 1
Brugia malayi Armadillo/beta-catenin-like repeat family protein 0.0101 0.1151 0.186
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.09 0.145
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0184 0.0279
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.0035 0.0027
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0532 0.9432
Onchocerca volvulus 0.001 0.0035 0.0054
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0163 0.195
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0528 0.6702
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0172 0.026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000010079 0.00000000016447
Loa Loa (eye worm) hypothetical protein 0.0016 0.0115 0.0166
Schistosoma mansoni histamine h1 receptor 0.001 0.0035 0.0054
Schistosoma mansoni DNA helicase recq5 0.002 0.0163 0.0309
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Echinococcus granulosus neuropeptides capa receptor 0.001 0.0035 0.0047
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0289 0.0694
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0137 0.1608
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Onchocerca volvulus 0.0014 0.0094 0.0202
Onchocerca volvulus 0.001 0.0035 0.0054
Schistosoma mansoni biogenic amine receptor 0.001 0.0035 0.0054
Loa Loa (eye worm) hypothetical protein 0.0014 0.0094 0.0131
Entamoeba histolytica hypothetical protein 0.0072 0.0796 1
Trichomonas vaginalis glucosylceramidase, putative 0.0511 0.6128 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0289 0.0451
Echinococcus multilocularis biogenic amine (5HT) receptor 0.001 0.0035 0.0027
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.001 0.0035 0.0054
Schistosoma mansoni smad1 5 8 and 0.0008 0.0019 0.0022
Onchocerca volvulus 0.001 0.0035 0.0054
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0697 0.0689
Schistosoma mansoni growth hormone secretagogue receptor 0.001 0.0035 0.0054
Echinococcus multilocularis dnaJ subfamily B 0.0421 0.5027 0.5023
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0008 0.0013 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0035 0.0027
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0.0035 0.0054
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0387 0.0632
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0532 0.7452
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0277 0.0432
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0387 0.0632
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0289 0.0561
Schistosoma mansoni hypothetical protein 0.001 0.0035 0.0054
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0289 0.0561
Echinococcus granulosus pangolin 0.0068 0.0742 0.1288
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0184 0.3097
Schistosoma mansoni biogenic amine receptor 0.001 0.0035 0.0054
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0008 0.0013 0.0006
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.071 0.8896
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0184 0.0309
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0043 0.0071
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0035 0.0054
Onchocerca volvulus 0.001 0.0035 0.0054
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0782 1
Brugia malayi RE15519p 0.001 0.0035 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0035 0.0047
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0289 0.0451
Entamoeba histolytica hypothetical protein 0.0072 0.0796 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.047 0.0811
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Brugia malayi Dopamine receptor protein 1 0.001 0.0035 0.0035
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0172 0.0164
Brugia malayi MH2 domain containing protein 0.0008 0.0019 0.0009
Echinococcus multilocularis lamin 0.0081 0.09 0.0893
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0172 0.0281
Echinococcus granulosus neuropeptide s receptor 0.0477 0.5709 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0289 0.0451
Schistosoma mansoni hypothetical protein 0.0072 0.0796 0.1571
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.3993 0.6516
Echinococcus granulosus intermediate filament protein 0.0081 0.09 0.1565
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0211 0.0344
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.071 0.1399
Loa Loa (eye worm) hypothetical protein 0.0021 0.0172 0.026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0387 0.5371
Schistosoma mansoni ran 0.0022 0.0184 0.0351
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus granulosus neuropeptide receptor 0.0162 0.1884 0.3291
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0796 0.0789
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.001 0.0035 0.0054
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0564 1
Entamoeba histolytica hypothetical protein 0.0072 0.0796 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0106 0.1206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.047 0.0922
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.071 0.1139
Brugia malayi steroid hormone receptor 0.0031 0.0289 0.0451
Echinococcus multilocularis neutral sphingomyelinase 0.0008 0.0013 0.0006
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0211 0.0344
Brugia malayi nuclear receptor NHR-88 0.0014 0.0094 0.0131
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0782 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.001 0.0035 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.4212 0.6874
Echinococcus multilocularis neuropeptide s receptor 0.0477 0.5709 0.5705
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0796 0.1571
Brugia malayi hypothetical protein 0.0072 0.0796 0.128
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0035 0.0027
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.047 0.0463
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.071 1
Schistosoma mansoni neuropeptide receptor 0.001 0.0035 0.0054
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0289 0.0694
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0289 0.0451
Echinococcus multilocularis neuropeptide receptor 0.0162 0.1884 0.1878
Echinococcus multilocularis importin subunit beta 1 0.003 0.0279 0.0271
Schistosoma mansoni ap endonuclease 0.0039 0.0387 0.0756
Onchocerca volvulus 0.003 0.0277 0.0663
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0019 0.0022
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0782 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0202 0.2377 0.3866
Schistosoma mansoni hypothetical protein 0.0064 0.0697 0.1372
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0163 0.0272
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0172 0.2066
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0528 0.6702
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0289 0.0561
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0172 0.026
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0094 0.0131
Echinococcus multilocularis T cell transcription factor 4 long C terminal 0.0068 0.0742 0.0735
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0444 0.0705
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.001 0.0035 0.0035
Echinococcus multilocularis G protein coupled receptor 139 0.0162 0.1884 0.1878
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0013 0.0022
Echinococcus granulosus lamin dm0 0.0081 0.09 0.1565
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0194 0.0186
Loa Loa (eye worm) hypothetical protein 0.0053 0.0564 0.09
Schistosoma mansoni intermediate filament proteins 0.0081 0.09 0.1777
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0013 0.0022
Schistosoma mansoni synaptojanin 0.0008 0.0013 0.0011
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0289 0.0494
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0289 0.0282
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.0035 0.0047
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0094 0.0131
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.00000000010079 0.00000000016447
Echinococcus multilocularis GPCR, family 2 0.0064 0.0697 0.0689
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.001 0.0035 0.0054
Brugia malayi G-protein coupled receptor 0.001 0.0035 0.0035
Schistosoma mansoni cpg binding protein 0.0031 0.0298 0.0578
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0289 0.0451
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0289 0.0282
Leishmania major pantothenate kinase subunit, putative 0.0011 0.0049 0.0458
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0387 0.5
Trichomonas vaginalis glucosylceramidase, putative 0.0511 0.6128 1
Echinococcus multilocularis deoxyribonuclease 1 2 0.0008 0.0013 0.0006
Echinococcus granulosus cpg binding protein 0.0031 0.0298 0.0509
Echinococcus granulosus traf and tnf receptor associated protein 0.0008 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0451
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus multilocularis fmrfamide receptor 0.001 0.0035 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0035 0.0047
Schistosoma mansoni hypothetical protein 0.0334 0.3971 0.7897
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0039 0.0061
Entamoeba histolytica Ran family GTPase 0.0022 0.0184 0.2176
Echinococcus multilocularis synaptojanin 1 0.0008 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Brugia malayi Serotonin receptor 0.001 0.0035 0.0035
Entamoeba histolytica recQ family helicase, putative 0.002 0.0163 0.1913
Echinococcus multilocularis somatostatin receptor 0.001 0.0035 0.0027
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0511 0.6128 1
Loa Loa (eye worm) Smad1 0.0008 0.0019 0.0009
Schistosoma mansoni nuclear receptor 0.0014 0.0094 0.0171
Echinococcus granulosus lamin 0.0081 0.09 0.1565
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0387 0.6798
Schistosoma mansoni opsin-like receptor 0.001 0.0035 0.0054
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0115 0.0166
Onchocerca volvulus 0.0021 0.0172 0.0399
Onchocerca volvulus 0.0158 0.1842 0.4595
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.0035 0.0027
Echinococcus granulosus dro:myosuppressin receptor 0.001 0.0035 0.0047
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0289 0.0451
Brugia malayi HMG box family protein 0.0068 0.0742 0.1192
Echinococcus granulosus Smad4 0.0008 0.0019 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0289 0.0451
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Schistosoma mansoni zinc finger protein 0.0014 0.0094 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.3993 0.6516
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0163 0.0266
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0564 0.7161
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0163 0.2151
Brugia malayi larval opioid receptor 0.001 0.0035 0.0035
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0289 0.0561
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0019 0.002
Trichomonas vaginalis ran, putative 0.0022 0.0184 0.03
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.071 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0782 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0019 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0782 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0782 1
Schistosoma mansoni hypothetical protein 0.0317 0.3763 0.7482
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0106 0.1585
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0172 0.2066
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.016 0.1856 0.3013
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.0035 0.0027
Echinococcus granulosus allatostatin A receptor 0.001 0.0035 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0289 0.0451
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0094 0.0171
Onchocerca volvulus 0.0014 0.0094 0.0202
Schistosoma mansoni neuropeptide receptor 0.001 0.0035 0.0054
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0172 0.2066
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0163 0.2723
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.001 0.0035 0.0054
Loa Loa (eye worm) intermediate filament protein 0.0081 0.09 0.145
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0163 0.0266
Echinococcus multilocularis serotonin receptor 0.001 0.0035 0.0027
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0019 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0035 0.0027
Onchocerca volvulus 0.001 0.0035 0.0054
Echinococcus granulosus synaptojanin 1 0.0008 0.0013 0.001
Onchocerca volvulus 0.001 0.0035 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0035 0.0054
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0043 0.043
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.001 0.0035 0.0027
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0035 0.0027
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Onchocerca volvulus 0.001 0.0035 0.0054
Brugia malayi ecdysteroid receptor 0.0031 0.0289 0.0451
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0019 0.0009
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0279 0.3812
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0387 0.6798
Brugia malayi sulfakinin receptor protein 0.001 0.0035 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0035 0.0027
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0163 0.2723
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.00000000010079 0.00000000016447
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0163 0.0155
Brugia malayi nuclear hormone receptor 0.0031 0.0289 0.0451
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0289 0.0451
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0163 0.0245
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.001 0.0035 0.0035
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.003 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0172 0.026
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.001 0.0035 0.0054
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0172 0.0327
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0451
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0094 0.0171
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0008 0.0013 0.0022
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0782 1
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.3993 0.6516
Loa Loa (eye worm) hypothetical protein 0.016 0.1856 0.3013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0451
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0094 0.0131
Schistosoma mansoni hypothetical protein 0.0421 0.5027 1
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0043 0.0545
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0035
Brugia malayi ORL1-like opioid receptor 0.001 0.0035 0.0035
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0782 0.1257
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.071 0.1231
Loa Loa (eye worm) oxidoreductase 0.0021 0.0172 0.026
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0172 0.2886
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0184 0.0279
Schistosoma mansoni myosin xvIII 0.001 0.0035 0.0054
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0279 0.3812
Brugia malayi hypothetical protein 0.001 0.0035 0.0035
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0289 0.0451
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0451
Brugia malayi latrophilin 2 splice variant baaae 0.0138 0.1599 0.2594
Onchocerca volvulus 0.0021 0.0172 0.0399
Schistosoma mansoni amine GPCR 0.001 0.0035 0.0054
Trichomonas vaginalis glucosylceramidase, putative 0.0511 0.6128 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0.0035 0.0054
Schistosoma mansoni lamin 0.0081 0.09 0.1777
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0094 0.015
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0106 0.1331
Loa Loa (eye worm) hypothetical protein 0.0016 0.0115 0.0166
Echinococcus granulosus 7tm_1 domain containing protein 0.001 0.0035 0.0047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.0035 0.0054
Echinococcus multilocularis smad 0.0008 0.0019 0.0011
Schistosoma mansoni synaptojanin 0.0008 0.0013 0.0011
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0289 0.0494
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0444 0.0705
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0172 0.228
Echinococcus granulosus dnaJ subfamily B 0.0421 0.5027 0.8804
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0289 0.0694
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0106 0.0196
Onchocerca volvulus 0.001 0.0035 0.0054
Brugia malayi Importin beta-1 subunit 0.003 0.0279 0.0434
Echinococcus granulosus fmrfamide receptor 0.001 0.0035 0.0047

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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