Detailed information for compound 675582

Basic information

Technical information
  • TDR Targets ID: 675582
  • Name: N-(3-fluoro-2-methylphenyl)-2-(4-methoxypheny l)acetamide
  • MW: 273.302 | Formula: C16H16FNO2
  • H donors: 1 H acceptors: 1 LogP: 3.13 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)CC(=O)Nc1cccc(c1C)F
  • InChi: 1S/C16H16FNO2/c1-11-14(17)4-3-5-15(11)18-16(19)10-12-6-8-13(20-2)9-7-12/h3-9H,10H2,1-2H3,(H,18,19)
  • InChiKey: JHPMNDXAXCCPLA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-fluoro-2-methyl-phenyl)-2-(4-methoxyphenyl)acetamide
  • N-(3-fluoro-2-methyl-phenyl)-2-(4-methoxyphenyl)ethanamide
  • AO-081/41135888
  • STK106833
  • ZINC00312603

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Leishmania major importin beta-1 subunit, putative 0.0019 0.0103 0.0197
Brugia malayi M-phase phosphoprotein, mpp8 0.0098 0.0874 0.2082
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0029 0.0029
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0142 0.0142
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0022 0.0007
Onchocerca volvulus 0.0012 0.0029 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0142 0.0309
Loa Loa (eye worm) heterochromatin protein 1 0.0011 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0362 1
Onchocerca volvulus 0.0012 0.0029 0.0032
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0011 0.0022 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Schistosoma mansoni cpg binding protein 0.0061 0.0515 0.0515
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0936 0.6281
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0011 0.0022 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0092 0.2901
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0025 0.0158 0.0347
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0029 0.0036
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0086 0.0754 0.0741
Loa Loa (eye worm) hypothetical protein 0.0022 0.0131 0.0281
Brugia malayi Inositol-1 0.0036 0.0264 0.0604
Schistosoma mansoni adenoreceptor 0.0012 0.0029 0.0029
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0142 0.0128
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0158 0.5625
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0029 0.0029
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0049 0.0263
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0029 0.0015
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0029 0.0015
Loa Loa (eye worm) transcription factor SMAD2 0.0094 0.084 0.1999
Echinococcus granulosus hypothetical protein 0.0012 0.0029 0.0015
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0264 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0029 0.0015
Loa Loa (eye worm) hypothetical protein 0.0107 0.0965 0.2302
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0029 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0029 0.0015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0309
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0029 0.0015
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0029 0.0036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0022 0.0001
Echinococcus granulosus Chromo domain 0.0011 0.0022 0.0007
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0254 0.2405 0.5793
Plasmodium falciparum importin beta, putative 0.0024 0.0147 0.3682
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0092 0.2047
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0018 0.0086 0.0071
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0029 0.0015
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0092 0.2537
Plasmodium falciparum transporter, putative 0.0038 0.0282 0.765
Echinococcus granulosus lamin 0.0048 0.0381 0.0367
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0086 0.0754 0.0741
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0069 0.0458
Trypanosoma brucei C-8 sterol isomerase, putative 0.0431 0.4141 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0022 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0142 0.0309
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0029 0.0015
Brugia malayi hypothetical protein 0.0038 0.0282 0.0648
Loa Loa (eye worm) hypothetical protein 0.0022 0.0131 0.0281
Brugia malayi latrophilin 2 splice variant baaae 0.0185 0.173 0.4156
Schistosoma mansoni ap endonuclease 0.0018 0.0092 0.0092
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0069 0.0115
Trypanosoma cruzi DNA polymerase eta, putative 0.0012 0.0034 0.0029
Schistosoma mansoni vesicular acetylcholine transporter 0.0266 0.2527 0.2527
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0029 0.0015
Brugia malayi Dopamine receptor protein 2 0.0012 0.0029 0.0036
Echinococcus multilocularis cpg binding protein 0.0065 0.0549 0.0535
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus geminin 0.0535 0.5167 0.5159
Loa Loa (eye worm) sodium/hydrogen exchanger 0.0045 0.0354 0.0821
Schistosoma mansoni ets-related 0.001 0.0015 0.0015
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.0282 0.0282
Brugia malayi hypothetical protein 0.0036 0.0269 0.0617
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0123 0.1123 0.111
Brugia malayi Heterochromatin protein 1 0.0011 0.0022 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0069 0.0115
Brugia malayi ImpB/MucB/SamB family protein 0.0012 0.0034 0.0046
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0022 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0254 0.2405 0.2405
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.0282 0.0282
Echinococcus granulosus dna polymerase eta 0.0012 0.0034 0.0019
Schistosoma mansoni terminal deoxycytidyl transferase 0.0012 0.0034 0.0034
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0515 0.1212
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0142 0.0128
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0029 0.0015
Onchocerca volvulus 0.0038 0.0282 0.104
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.0282 0.0648
Brugia malayi Dopamine receptor protein 1 0.0012 0.0029 0.0036
Brugia malayi neuropeptide F receptor 0.0012 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0141 0.1301 0.3116
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0142 0.0309
Trypanosoma cruzi DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Onchocerca volvulus 0.0048 0.0381 0.1434
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Echinococcus granulosus dna polymerase kappa 0.0012 0.0034 0.0019
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0029 0.0029
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0022 0.0001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0011 0.0022 0.0007
Loa Loa (eye worm) hypothetical protein 0.0048 0.0381 0.0887
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0022 0.0001
Loa Loa (eye worm) hypothetical protein 0.0185 0.173 0.4156
Echinococcus granulosus snurportin 1 0.0254 0.2405 0.2394
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0142 0.0142
Brugia malayi neuropeptide F receptor 0.0012 0.0029 0.0036
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0609 0.0595
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0069 0.0274
Echinococcus granulosus short transient receptor potential channel 6 0.0094 0.0831 0.0818
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0431 0.4141 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.0282 0.0648
Onchocerca volvulus 0.0012 0.0029 0.0032
Echinococcus granulosus thyroid hormone receptor alpha 0.0011 0.0022 0.0007
Toxoplasma gondii isocitrate dehydrogenase 0.0012 0.003 0.0075
Schistosoma mansoni DNA polymerase eta 0.0012 0.0034 0.0034
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0018 0.0086 0.0172
Echinococcus multilocularis serotonin receptor 0.0012 0.0029 0.0015
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0022 0.0022
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0016 0.0073 0.0059
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0022 0.0007
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0029 0.0029
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0116 0.0246
Loa Loa (eye worm) nuclear receptor NHR-67 0.0011 0.0022 0.0017
Echinococcus granulosus somatostatin receptor 0.0012 0.0029 0.0015
Schistosoma mansoni biogenic amine receptor 0.0012 0.0029 0.0029
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0029 0.0015
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0011 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis serotonin receptor 0.0012 0.0029 0.0015
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0022 0.0022
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0097 0.02
Schistosoma mansoni elf1 0.001 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0048
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus tumor protein p63 0.0331 0.3159 0.3149
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0142 0.0309
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0085 0.2607
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0038 0.0282 0.0268
Onchocerca volvulus 0.0098 0.0874 0.3403
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0018 0.0086 0.0155
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0029 0.0036
Echinococcus granulosus sex peptide receptor 0.0012 0.0029 0.0015
Toxoplasma gondii HEAT repeat-containing protein 0.0024 0.0147 0.1216
Leishmania major C-8 sterol isomerase-like protein 0.0431 0.4141 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0069 0.0115
Schistosoma mansoni ets-related 0.0215 0.2025 0.2025
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0012 0.0034 0.0028
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0022 0.0022
Echinococcus multilocularis snurportin 1 0.0254 0.2405 0.2394
Mycobacterium tuberculosis Probable esterase LipL 0.0025 0.0158 0.0888
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0142 0.0309
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0309
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0069 0.1389
Schistosoma mansoni inositol monophosphatase 0.0036 0.0264 0.0264
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0011 0.0022 0.0002
Loa Loa (eye worm) hypothetical protein 0.0048 0.0389 0.0907
Echinococcus multilocularis geminin 0.0535 0.5167 0.5159
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0309
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0045 0.0354 0.0339
Toxoplasma gondii exonuclease III APE 0.0018 0.0092 0.0681
Trypanosoma brucei PAB1-binding protein , putative 0.0036 0.0269 0.06
Trypanosoma brucei importin beta-1 subunit, putative 0.0024 0.0147 0.0304
Echinococcus multilocularis beta LACTamase domain containing family member 0.0025 0.0158 0.0143
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0266 0.2527 0.6087
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0029 0.0015
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0069 0.0115
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0022 0.0000000010122
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0056 0.0042
Plasmodium vivax ataxin-2 like protein, putative 0.0036 0.0269 0.7266
Loa Loa (eye worm) hypothetical protein 0.0045 0.0354 0.0821
Schistosoma mansoni importin beta-1 0.0024 0.0147 0.0147
Schistosoma mansoni hypothetical protein 0.0016 0.0073 0.0073
Schistosoma mansoni hypothetical protein 0.0535 0.5167 0.5167
Onchocerca volvulus 0.0012 0.0029 0.0032
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.0282 0.0282
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0086 0.0754 0.0741
Brugia malayi nuclear hormone receptor family member odr-7 0.0011 0.0022 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0362 0.2303
Schistosoma mansoni amine GPCR 0.0012 0.0029 0.0029
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.0282 0.0648
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0022 0.0000000010122
Brugia malayi larval opioid receptor 0.0012 0.0029 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0029 0.0036
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0056 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Echinococcus granulosus sodium:hydrogen exchanger 2 (nhe2) 0.0036 0.027 0.0255
Trypanosoma cruzi PAB1-binding protein , putative 0.0036 0.0269 0.06
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0142 0.0309
Schistosoma mansoni microtubule-associated protein tau 0.1028 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0075 0.0147
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0107 0.0966 0.2305
Schistosoma mansoni biogenic amine receptor 0.0012 0.0029 0.0029
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0038 0.0282 0.0268
Onchocerca volvulus 0.0012 0.0029 0.0032
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0264 0.0588
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0116 0.0102
Brugia malayi Serotonin receptor 0.0012 0.0029 0.0036
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0018 0.0086 0.0155
Schistosoma mansoni amine GPCR 0.0012 0.0029 0.0029
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0056 0.0056
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0022 0.0007
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0029 0.0029
Mycobacterium ulcerans esterase/lipase LipP 0.0025 0.0158 0.5393
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0025 0.0158 0.0158
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0012 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0309
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.1051 1
Echinococcus multilocularis somatostatin receptor 0.0012 0.0029 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.1159
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0029 0.0036
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0045 0.0354 0.0339
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0045 0.0354 0.1326
Trypanosoma brucei DNA polymerase IV, putative 0.0012 0.0034 0.0029
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0362 0.0348
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Leishmania major hypothetical protein, conserved 0.0036 0.0269 0.06
Brugia malayi nuclear receptor RXR 0.0011 0.0022 0.0017
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0029 0.0029
Brugia malayi Thioredoxin reductase 0.0046 0.0362 0.0842
Echinococcus granulosus cpg binding protein 0.0065 0.0549 0.0535
Loa Loa (eye worm) hypothetical protein 0.0036 0.0269 0.0617
Echinococcus granulosus bloom syndrome protein 0.0021 0.0116 0.0102
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0045 0.0354 0.0339
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.0282 0.0648
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0018
Brugia malayi G-protein coupled receptor 0.0012 0.0029 0.0036
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0034 0.0048
Onchocerca volvulus 0.0012 0.0029 0.0032
Onchocerca volvulus 0.0012 0.0029 0.0032
Brugia malayi Dopamine receptor 0.0012 0.0029 0.0036
Echinococcus multilocularis sex peptide receptor 0.0012 0.0029 0.0015
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0012 0.003 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0142 0.0309
Brugia malayi nuclear hormone receptor 0.0023 0.0142 0.0309
Plasmodium vivax importin-beta 2, putative 0.0024 0.0147 0.3682
Schistosoma mansoni opsin-like receptor 0.0012 0.0029 0.0029
Brugia malayi ORL1-like opioid receptor 0.0012 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0282 0.0648
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0018
Mycobacterium ulcerans beta-lactamase 0.0025 0.0158 0.5393
Schistosoma mansoni transient receptor potential channel 0.0141 0.1301 0.1301
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.01 0.0085
Onchocerca volvulus 0.0038 0.0282 0.104
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0766 0.0766
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0936 0.6281
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0022 0.0007
Schistosoma mansoni hypothetical protein 0.0086 0.0754 0.0754
Brugia malayi GnHR receptor homolog 0.0012 0.0029 0.0036
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0362 0.0842
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0022 0.0001
Brugia malayi hypothetical protein 0.0012 0.0034 0.0048
Schistosoma mansoni hypothetical protein 0.0123 0.1123 0.1123
Brugia malayi RE15519p 0.0012 0.0029 0.0036
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0766 0.0766
Echinococcus granulosus chromobox protein 1 0.0011 0.0022 0.0007
Onchocerca volvulus 0.0048 0.0389 0.1466
Brugia malayi Protein cec-1. 0.0011 0.0022 0.0018
Schistosoma mansoni nuclear receptor nhr-48 0.0011 0.0022 0.0022
Brugia malayi RNA, U transporter 1 0.0068 0.0578 0.1364
Onchocerca volvulus 0.0025 0.0158 0.0544
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0142 0.0142
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.0282 0.0648
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0016 0.0073 0.0059
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0142 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.1159
Schistosoma mansoni hypothetical protein 0.001 0.0015 0.0015
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0011 0.0022 0.0017
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0123 0.1123 0.111
Echinococcus granulosus orexin receptor type 2 0.0012 0.0029 0.0015
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0069 0.1952
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0158 0.5625
Schistosoma mansoni chromobox protein 0.0011 0.0022 0.0022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0107 0.0966 0.0953
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Echinococcus granulosus neuropeptide receptor 0.0012 0.0029 0.0015
Schistosoma mansoni neuropeptide receptor 0.0012 0.0029 0.0029
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0029 0.0029
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0142 0.0309
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0766 0.0752
Loa Loa (eye worm) hypothetical protein 0.0038 0.0282 0.0648
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0069 0.0115
Brugia malayi SET domain containing protein 0.0012 0.0035 0.0049
Loa Loa (eye worm) hypothetical protein 0.0221 0.2084 0.5014
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0022 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0048
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0025 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Schistosoma mansoni transient receptor potential channel 0.0094 0.0831 0.0831
Echinococcus granulosus neuropeptide receptor 0.0012 0.0029 0.0015
Echinococcus granulosus transient receptor potential gamma protein 0.0141 0.1301 0.1288
Trichomonas vaginalis importin beta-1, putative 0.0019 0.0103 0.3352
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0142 0.0128
Schistosoma mansoni lamin 0.0048 0.0381 0.0381
Echinococcus granulosus vesicular acetylcholine transporter 0.0266 0.2527 0.2516
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0936 0.8722
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0022 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0048
Brugia malayi AKH receptor 0.0012 0.0029 0.0036
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0036 0.027 0.0255
Echinococcus multilocularis short transient receptor potential channel 6 0.0094 0.0831 0.0818
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0142 0.0309
Echinococcus granulosus chromobox protein 1 0.0011 0.0022 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Schistosoma mansoni gabp alpha 0.0071 0.0609 0.0609
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0282 0.765
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0086 0.0754 0.0741
Onchocerca volvulus 0.0025 0.0158 0.0544
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0011 0.0022 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0142 0.0309
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0029 0.0015
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0051 0.0843
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0142 0.0142
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0092 0.0188
Echinococcus multilocularis isocitrate dehydrogenase 0.0012 0.003 0.0015
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0092 0.2063
Plasmodium falciparum glutathione reductase 0.0046 0.0362 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0018 0.0086 0.0155
Echinococcus granulosus dnaJ subfamily B 0.0872 0.8472 0.847
Leishmania major GTP-binding protein, putative 0.0018 0.0086 0.0155
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0038 0.0282 0.0648
Schistosoma mansoni hypothetical protein 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0038 0.0282 1
Schistosoma mansoni amine GPCR 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0018
Onchocerca volvulus 0.0023 0.0142 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Schistosoma mansoni ets 0.001 0.0015 0.0015
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0069 0.0115
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0069 0.0115
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.1051 0.7072
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0029 0.0015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0025 0.0158 0.0888
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0012 0.003 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0282 0.0648
Mycobacterium tuberculosis Probable reductase 0.0104 0.0936 0.6281
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0142 0.0482
Loa Loa (eye worm) MH2 domain-containing protein 0.0094 0.084 0.1999
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Loa Loa (eye worm) nuclear hormone receptor 0.0011 0.0022 0.0017
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0142 0.0482
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0142 0.0309
Echinococcus multilocularis nuclear receptor nhr 48 0.0011 0.0022 0.0007
Brugia malayi nuclear receptor NHR-67 0.0011 0.0022 0.0017
Schistosoma mansoni hypothetical protein 0.0012 0.0029 0.0029
Onchocerca volvulus 0.0048 0.0381 0.1434
Brugia malayi beta-lactamase family protein 0.0025 0.0158 0.0347
Echinococcus granulosus sodium:hydrogen exchanger 0.0045 0.0354 0.0339
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0046
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0362 0.0348
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.0282 0.0282
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Brugia malayi sulfakinin receptor protein 0.0012 0.0029 0.0036
Onchocerca volvulus 0.0012 0.0029 0.0032
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0092 0.2901
Brugia malayi Melatonin receptor type 1A 0.0012 0.0029 0.0036
Schistosoma mansoni hypothetical protein 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0309
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0936 0.6281
Giardia lamblia Sodium/hydrogen exchanger 3 0.0045 0.0354 1
Echinococcus granulosus g protein coupled receptor 0.0012 0.0029 0.0015
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0029 0.0015
Echinococcus granulosus neuropeptide receptor A26 0.0338 0.3229 0.3219
Echinococcus granulosus neuropeptide s receptor 0.0338 0.3229 0.3219
Schistosoma mansoni cpg binding protein 0.0065 0.0549 0.0549
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0092 0.1826
Brugia malayi hypothetical protein 0.0023 0.0143 0.0311
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0142 0.0309
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0022 0.0007
Brugia malayi follicle stimulating hormone receptor 0.0012 0.0029 0.0036
Schistosoma mansoni opsin-like receptor 0.0012 0.0029 0.0029
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0022 0.0007
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0029 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0147 0.1351 0.1351
Plasmodium falciparum ataxin-2 like protein, putative 0.0036 0.0269 0.7266
Loa Loa (eye worm) hypothetical protein 0.0047 0.0372 0.0867
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0029 0.0015
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0029 0.0029
Brugia malayi Importin beta-1 subunit 0.0024 0.0147 0.0321
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0069 0.0132
Onchocerca volvulus 0.0061 0.0515 0.1969
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0092 0.2901
Brugia malayi ecdysteroid receptor 0.0023 0.0142 0.0309
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.0282 0.0268
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.0045 0.0354 0.0821
Schistosoma mansoni ap endonuclease 0.0018 0.0092 0.0092
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0107 0.0966 0.2305
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0028 0.0032
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0029 0.0015
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0012 0.003 0.003
Schistosoma mansoni thyroid hormone receptor 0.0147 0.1351 0.1351
Schistosoma mansoni sodium/hydrogen exchanger 2 (nhe2) 0.0045 0.0354 0.0354
Echinococcus multilocularis chromobox protein 1 0.0011 0.0022 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0019 0.0103 0.3352
Schistosoma mansoni chromobox protein 0.0011 0.0022 0.0022
Schistosoma mansoni coup transcription factor 0.0023 0.0142 0.0142
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0026 0.0164 0.0362
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0063 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0158 0.5625
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0264 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0025 0.0158 0.0347
Loa Loa (eye worm) hypothetical protein 0.0098 0.0874 0.2082
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0264 0.0588
Loa Loa (eye worm) hypothetical protein 0.022 0.2075 0.4992
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis vesicular acetylcholine transporter 0.0266 0.2527 0.2516
Brugia malayi Ets-domain containing protein 0.0071 0.0609 0.1441
Echinococcus multilocularis serotonin transporter 0.0221 0.2084 0.2072
Schistosoma mansoni lamin 0.0048 0.0381 0.0381
Brugia malayi cytoplasmic intermediate filament protein 0.0026 0.0164 0.0362
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0022 0.0007
Loa Loa (eye worm) hypothetical protein 0.0025 0.0158 0.0347
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0012 0.0034 0.0019
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0069 0.0115
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0023 0.0139 0.0125
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0022 0.0001
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0034 0.002
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0038 0.0282 0.0268
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0069 0.1952
Brugia malayi vesicular acetylcholine transporter unc-17 0.0266 0.2527 0.6087
Echinococcus granulosus Chromobox protein 3 0.0011 0.0022 0.0007
Schistosoma mansoni chromobox protein 0.0011 0.0022 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0022 0.0001
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0029 0.0015
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0029 0.0015
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0011 0.0022 0.0007
Schistosoma mansoni hypothetical protein 0.001 0.0015 0.0015
Trypanosoma brucei DNA polymerase eta, putative 0.0012 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0092 0.0188
Onchocerca volvulus 0.0107 0.0965 0.3765
Schistosoma mansoni hypothetical protein 0.0011 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0029 0.0029
Schistosoma mansoni ran 0.0018 0.0086 0.0086
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0069 0.1389
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0221 0.2084 0.2084
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0142 0.0128
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0012 0.003 0.0019
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0029 0.0015
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0431 0.4141 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0754 0.1792
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis musashi 0.0048 0.0381 0.0367
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0069 0.1389
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0142 0.0309
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0018
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0045 0.0354 0.0339
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0092 0.017
Echinococcus granulosus GTP binding nuclear protein Ran 0.0018 0.0086 0.0071
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.1051 0.7072
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0142 0.0128
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0056 0.0042
Plasmodium falciparum thioredoxin reductase 0.0046 0.0362 1
Loa Loa (eye worm) sodium/hydrogen exchanger 3 family protein 0.0045 0.0354 0.0821
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0025 0.0158 0.0888
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0142 0.0142
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0086 0.0754 0.1792
Loa Loa (eye worm) hypothetical protein 0.0089 0.0785 0.1866
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0362 0.0826
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.0282 0.0282
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0092 0.0114
Trichomonas vaginalis hypothetical protein 0.0011 0.0022 0.0001
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0069 0.154
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0142 0.0128
Entamoeba histolytica Ran family GTPase 0.0018 0.0086 0.263
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0142 0.0128
Schistosoma mansoni nuclear receptor 0.0011 0.0022 0.0022
Echinococcus multilocularis chromobox protein 1 0.0011 0.0022 0.0007
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0069 0.154
Trichomonas vaginalis penicillin-binding protein, putative 0.0025 0.0158 0.5618
Schistosoma mansoni nuclear receptor 0.0011 0.0022 0.0022
Brugia malayi Latrophilin receptor protein 2 0.0086 0.0754 0.1792
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0142 0.0128
Trypanosoma cruzi DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Onchocerca volvulus 0.0038 0.0282 0.104
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0069 0.0115
Loa Loa (eye worm) hypothetical protein 0.0038 0.0282 0.0648
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0092 0.1178
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0029 0.0032
Loa Loa (eye worm) hypothetical protein 0.0048 0.0383 0.0893
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Loa Loa (eye worm) isocitrate dehydrogenase 0.0012 0.003 0.0036
Schistosoma mansoni cpg binding protein 0.0065 0.0549 0.0549
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0069 0.1108
Brugia malayi glutathione reductase 0.0046 0.0362 0.0842
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0142 0.0128
Brugia malayi tailless protein 0.0011 0.0022 0.0017
Loa Loa (eye worm) hypothetical protein 0.0038 0.0282 0.0648
Loa Loa (eye worm) hypothetical protein 0.0038 0.0282 0.0648
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.1052 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0092 0.017
Loa Loa (eye worm) DR-78 0.0011 0.0022 0.0017
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0142 0.0128
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0309
Trichomonas vaginalis penicillin-binding protein, putative 0.0025 0.0158 0.5618
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0069 0.154
Trichomonas vaginalis ran, putative 0.0018 0.0086 0.263
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0034 0.0034
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0053 0.043 0.0416
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0142 0.0128
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus importin subunit beta 1 0.0024 0.0147 0.0133
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0018
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0029 0.0036
Brugia malayi chromobox protein homolog 3 0.0011 0.0022 0.0018
Echinococcus granulosus g protein coupled receptor 0.0012 0.0029 0.0015
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0264 0.025
Leishmania major DNA polymerase eta, putative 0.0012 0.0034 0.0029
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0029 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0142 0.0309
Onchocerca volvulus 0.0012 0.0029 0.0032
Schistosoma mansoni hypothetical protein 0.0012 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0038 0.0282 0.0268
Brugia malayi Fli-1 protein 0.0215 0.2025 0.4872
Echinococcus granulosus serotonin receptor 0.0012 0.0029 0.0015
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0022 0.0017
Brugia malayi Intermediate filament tail domain containing protein 0.0048 0.0381 0.0887
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Brugia malayi G-protein coupled receptor 0.0012 0.0029 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0029 0.0015
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0025 0.0158 0.5393
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0158 0.5625
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0142 0.0309
Loa Loa (eye worm) hypothetical protein 0.0045 0.0354 0.0821
Schistosoma mansoni biogenic amine receptor 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0029 0.0015
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0034 0.0034
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0045 0.0354 0.1326
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0022 0.0007
Loa Loa (eye worm) hypothetical protein 0.0431 0.4141 1
Schistosoma mansoni sodium/hydrogen exchanger 0.0045 0.0354 0.0354
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0029 0.0015
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0069 0.0115
Echinococcus multilocularis transient receptor potential gamma protein 0.0141 0.1301 0.1288
Brugia malayi MH2 domain containing protein 0.0094 0.084 0.1999
Loa Loa (eye worm) hypothetical protein 0.0053 0.043 0.1005
Trypanosoma brucei DNA polymerase IV, putative 0.0012 0.0034 0.0029
Brugia malayi intermediate filament protein 0.0048 0.0381 0.0887
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0012 0.003 0.0019
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0029 0.0015
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0018 0.0086 0.1871
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0095 0.3019
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0029 0.0036
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0048 0.0381 0.0887
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis neuropeptide receptor A26 0.0338 0.3229 0.3219
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0069 0.0055
Loa Loa (eye worm) hypothetical protein 0.0098 0.0874 0.2082
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0107 0.0966 0.0966
Echinococcus granulosus short transient receptor potential channel 6 0.0094 0.0831 0.0818
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0029 0.0015
Loa Loa (eye worm) hypothetical protein 0.0025 0.0158 0.0347
Schistosoma mansoni hypothetical protein 0.0086 0.0754 0.0754
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0022 0.00000000033422
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0142 0.0309
Brugia malayi nuclear receptor NHR-88 0.0023 0.0142 0.0309
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0069 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.1159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0029 0.0029
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0142 0.0128
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0019 0.0103 0.3352
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0029 0.0015
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.0282 0.0282
Loa Loa (eye worm) serotonin transporter b 0.0221 0.2084 0.5014
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0264 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0035 0.0035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0029 0.0029
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0029 0.0015
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0029 0.0036
Loa Loa (eye worm) norepinephrine transporter 0.0221 0.2084 0.5014
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0074 0.0074
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0264 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0092 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Schistosoma mansoni inositol monophosphatase 0.0036 0.0264 0.0264
Echinococcus granulosus g protein coupled receptor 0.0012 0.0029 0.0015
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0012 0.0034 0.0029
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0029 0.0015
Plasmodium falciparum thioredoxin reductase 0.0016 0.0069 0.1389
Echinococcus granulosus GPCR family 2 0.0086 0.0754 0.0741
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.0282 0.2526
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0022 0.0017
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis microtubule associated protein 2 0.1028 1 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0116 0.3892
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0107 0.0966 0.0953
Schistosoma mansoni amine GPCR 0.0012 0.0029 0.0029
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0158 0.3997
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Onchocerca volvulus 0.0012 0.0029 0.0032
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0158 0.033
Loa Loa (eye worm) hypothetical protein 0.0061 0.0508 0.1196
Schistosoma mansoni transient receptor potential channel 4 0.0141 0.1301 0.1301
Brugia malayi nuclear receptor NHR-88 0.0011 0.0022 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0271 0.257 0.6193
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.0282 0.0268
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0069 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.1159
Echinococcus multilocularis tumor protein p63 0.0331 0.3159 0.3149
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0158 0.033
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0029 0.0036
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0029 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0142 0.0309
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0029 0.0015
Mycobacterium tuberculosis Conserved protein 0.0025 0.0158 0.0888
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0142 0.0309
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0029 0.0036
Brugia malayi hypothetical protein 0.0098 0.0874 0.2082
Trypanosoma cruzi PAB1-binding protein , putative 0.0036 0.0269 0.06
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0095 0.3019
Schistosoma mansoni sodium/chloride dependent transporter 0.0221 0.2084 0.2084
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0029 0.0015
Schistosoma mansoni transient receptor potential channel 0.0094 0.0831 0.0831
Schistosoma mansoni ran 0.0018 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0535 0.5167 0.5167
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0158 0.5618
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0069 0.0115
Leishmania major DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Schistosoma mansoni chromobox protein 0.0011 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0221 0.2084 0.5014
Mycobacterium tuberculosis Conserved protein 0.0025 0.0158 0.0888
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0012 0.003 0.0015
Brugia malayi putative neuropeptide receptor 0.0012 0.0029 0.0036
Mycobacterium tuberculosis Conserved protein 0.0025 0.0158 0.0888
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.0282 0.0268
Schistosoma mansoni neuropeptide receptor 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0159 0.1473 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0029 0.0029
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0264 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0029 0.0029
Brugia malayi hypothetical protein 0.0011 0.0022 0.0017
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0227 0.1369
Onchocerca volvulus 0.0012 0.0029 0.0032
Mycobacterium tuberculosis Probable lipase LipE 0.0025 0.0158 0.0888
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0227 0.0777
Schistosoma mansoni hypothetical protein 0.0185 0.173 0.173
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.1159
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0022 0.0018
Schistosoma mansoni histamine h1 receptor 0.0012 0.0029 0.0029
Brugia malayi beta-lactamase family protein 0.0025 0.0158 0.0347
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0029 0.0036
Plasmodium falciparum ataxin-2 like protein, putative 0.0036 0.0269 0.7266
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0029 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Schistosoma mansoni neuropeptide receptor 0.0012 0.0029 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Toxoplasma gondii hypothetical protein 0.0038 0.0282 0.2526
Brugia malayi Serotonin receptor 0.0012 0.0029 0.0036
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0142 0.0309
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0038 0.0282 0.0268
Schistosoma mansoni myosin xvIII 0.0012 0.0029 0.0029
Trypanosoma brucei DNA polymerase IV, putative 0.0012 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0034 0.002
Plasmodium vivax glutathione reductase, putative 0.0046 0.0362 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0139 0.0302
Schistosoma mansoni amine GPCR 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Trypanosoma cruzi importin beta-1 subunit, putative 0.0019 0.0103 0.0197
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0092 0.017
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0029 0.0015
Brugia malayi nuclear hormone receptor family member nhr-6 0.0011 0.0022 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0069 0.0458
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0012 0.003 0.0228
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0038 0.0282 0.0648
Schistosoma mansoni hypothetical protein 0.0086 0.0754 0.0754
Trichomonas vaginalis helicase, putative 0.0014 0.005 0.1159
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0029 0.0029
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0264 0.0588
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0107 0.0966 0.0953
Loa Loa (eye worm) helicase 0.0011 0.0022 0.0018
Trypanosoma brucei trypanothione reductase 0.0046 0.0362 0.0826
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0264 0.0588
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0029 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0034 0.0048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0023 0.0139 0.0125
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0029 0.0036
Trypanosoma brucei importin beta-1 subunit, putative 0.0024 0.0147 0.0304
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0012 0.0034 0.0046
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0029 0.0015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0022 0.0001
Plasmodium falciparum glutathione reductase 0.0016 0.0069 0.1389
Onchocerca volvulus 0.0012 0.0029 0.0032
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0029 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0107 0.0966 0.0966
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0029 0.0036
Loa Loa (eye worm) beta-lactamase 0.0025 0.0158 0.0347
Schistosoma mansoni neuropeptide receptor 0.0012 0.0029 0.0029
Echinococcus granulosus tm gpcr rhodopsin 0.0416 0.3992 0.3983
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0029 0.0015
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0142 0.0128
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Brugia malayi CHD4 protein 0.0015 0.0056 0.0101
Schistosoma mansoni hypothetical protein 0.0086 0.0754 0.0754
Echinococcus multilocularis importin subunit beta 1 0.0024 0.0147 0.0133
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0158 0.5618
Echinococcus granulosus TRP transient receptor potential channel 0.0053 0.043 0.0416
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0029 0.0015
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0063 0.0048
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0012 0.0029 0.0036
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0012 0.003 0.0015
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0018 0.0086 0.0618
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.0282 0.2526
Toxoplasma gondii hypothetical protein 0.0038 0.0282 0.2526
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0063 0.0048
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0029 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0158 0.5625
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0015 0.0015
Brugia malayi isocitrate dehydrogenase 0.0012 0.003 0.0036
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0266 0.2527 1
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0029 0.0015
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.0282 0.0282
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0069 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0029 0.0015
Echinococcus granulosus fmrfamide receptor 0.0012 0.0029 0.0015
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0069 0.0055
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Entamoeba histolytica hypothetical protein 0.0011 0.0022 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Onchocerca volvulus 0.0221 0.2084 0.8232
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0063 0.0063
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0264 0.2349
Onchocerca volvulus 0.0012 0.0029 0.0032
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0029 0.0036
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0029 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Schistosoma mansoni opsin-like receptor 0.0012 0.0029 0.0029
Trypanosoma brucei unspecified product 0.0012 0.0034 0.0029
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0045 0.0354 0.0339
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0012 0.003 0.0015
Echinococcus multilocularis neuropeptide s receptor 0.0338 0.3229 0.3219
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0022 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0029 0.0015
Onchocerca volvulus 0.0012 0.0029 0.0032
Loa Loa (eye worm) histone methyltransferase 0.0019 0.01 0.0206
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0158 0.5625
Schistosoma mansoni sodium/chloride dependent transporter 0.0038 0.0282 0.0282
Echinococcus multilocularis lamin 0.0048 0.0381 0.0367
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.1051 0.7072
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0092 0.0078
Brugia malayi Ets-domain containing protein 0.0071 0.0609 0.1441
Leishmania major trypanothione reductase 0.0046 0.0362 0.0826
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0022 0.0001
Echinococcus multilocularis short transient receptor potential channel 6 0.0094 0.0831 0.0818
Brugia malayi Transient-receptor-potential like protein 0.0053 0.043 0.1005
Brugia malayi nuclear receptor RXR 0.0012 0.0034 0.0048
Leishmania major hypothetical protein, conserved 0.0025 0.0158 0.033
Entamoeba histolytica hypothetical protein 0.0019 0.0103 0.3352
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0092 0.0433
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0936 0.6281
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.1188 0.1188
Onchocerca volvulus 0.0012 0.0029 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0012 0.003 0.0015
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0029 0.0015
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0011 0.0022 0.0022
Loa Loa (eye worm) intermediate filament protein 0.0048 0.0381 0.0887
Trypanosoma cruzi DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0012 0.0034 0.0029
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0142 0.0142
Toxoplasma gondii ABC1 family protein 0.0025 0.0158 0.132
Brugia malayi beta-lactamase 0.0025 0.0158 0.0347
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.0282 0.0268
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0309
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.1159
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0107 0.0966 0.0953
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0029 0.0015
Brugia malayi steroid hormone receptor 0.0023 0.0142 0.0309
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.0282 0.0268
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0018 0.0086 0.1621
Loa Loa (eye worm) hypothetical protein 0.0025 0.0158 0.0347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0107 0.0966 0.0966
Onchocerca volvulus 0.0012 0.0029 0.0032
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0029 0.0029
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0069 0.1389
Onchocerca volvulus 0.0025 0.0158 0.0544
Loa Loa (eye worm) hypothetical protein 0.0024 0.0147 0.0321
Schistosoma mansoni intermediate filament proteins 0.0048 0.0381 0.0381
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0029 0.0029
Brugia malayi hypothetical protein 0.0011 0.0022 0.0017
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0264 1
Onchocerca volvulus 0.0012 0.0029 0.0032
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0264 0.025
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0158 0.033
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.0282 0.0282
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0029 0.0036
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0029 0.0036
Loa Loa (eye worm) glutathione reductase 0.0046 0.0362 0.0842
Loa Loa (eye worm) RecQ helicase 0.0021 0.0116 0.0246
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0271 0.257 0.6193
Brugia malayi hypothetical protein 0.0012 0.0029 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Entamoeba histolytica hypothetical protein 0.0011 0.0022 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0221 0.2084 0.5014
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0271 0.257 0.6193
Mycobacterium tuberculosis Probable lipase LipD 0.0025 0.0158 0.0888
Loa Loa (eye worm) solute carrier family 6 member 4 0.0221 0.2084 0.5014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0029 0.0015
Schistosoma mansoni sodium-dependent amino acid transporter 0.0038 0.0282 0.0282
Brugia malayi nuclear hormone receptor 0.0011 0.0022 0.0017
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0029 0.0036
Echinococcus granulosus beta LACTamase domain containing family member 0.0025 0.0158 0.0143
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0029 0.0015
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.0282 0.2526
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0872 0.8472 0.8472
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0142 0.0128
Toxoplasma gondii LsmAD domain-containing protein 0.0036 0.0269 0.2399
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.0282 0.0268
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Echinococcus granulosus transient receptor potential ion channel A 0.0137 0.1254 0.1242
Echinococcus granulosus nuclear receptor nhr 48 0.0011 0.0022 0.0007
Toxoplasma gondii thioredoxin reductase 0.0046 0.0362 0.3302
Entamoeba histolytica hypothetical protein 0.0011 0.0022 0.0001
Plasmodium vivax amine transporter, putative 0.0038 0.0282 0.765
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0025 0.0158 0.0888
Echinococcus multilocularis dna polymerase eta 0.0012 0.0034 0.0019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0012 0.003 0.0015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0142 0.0142
Trichomonas vaginalis DNA polymerase eta, putative 0.0012 0.0034 0.0488
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0142 0.0128
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0142 0.0128
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0142 0.0142
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0029 0.0015
Brugia malayi CXXC zinc finger family protein 0.0061 0.0515 0.1212
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0029 0.0015
Echinococcus granulosus serotonin transporter 0.0221 0.2084 0.2072
Echinococcus multilocularis chromobox protein 2 0.0011 0.0022 0.0007
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0063 0.0048
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0116 0.3892
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Echinococcus multilocularis dna polymerase kappa 0.0012 0.0034 0.0019
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0029 0.0015
Brugia malayi ImpB/MucB/SamB family protein 0.0012 0.0034 0.0046
Treponema pallidum sodium- and chloride- dependent transporter 0.0221 0.2084 1
Schistosoma mansoni zinc finger protein 0.0011 0.0022 0.0022
Loa Loa (eye worm) fli-1 protein 0.0215 0.2025 0.4872
Loa Loa (eye worm) latrophilin receptor protein 2 0.0086 0.0754 0.1792
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0045 0.0354 0.1326
Brugia malayi conserved hypotetical protein 0.0011 0.0022 0.0017
Toxoplasma gondii isocitrate dehydrogenase 0.0012 0.003 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.1159
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0029 0.0015
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0029 0.0032
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0142 0.0128
Mycobacterium tuberculosis Conserved hypothetical protein 0.0012 0.0034 0.0028
Echinococcus granulosus intermediate filament protein 0.0048 0.0381 0.0367
Echinococcus multilocularis GPCR, family 2 0.0086 0.0754 0.0741
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0012 0.003 0.0019
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0609 0.0595
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0092 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0142 0.0309
Loa Loa (eye worm) NHE-3 0.0045 0.0354 0.0821
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0048
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0025 0.0158 0.0347
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0389 0.0389
Echinococcus granulosus chromobox protein 2 0.0011 0.0022 0.0007
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0012 0.0034 0.0019
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0158 0.5625
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0092 0.2063
Echinococcus granulosus lamin dm0 0.0048 0.0381 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.1159
Brugia malayi hypothetical protein 0.0107 0.0965 0.2302
Loa Loa (eye worm) inositol-1 0.0036 0.0264 0.0604
Echinococcus granulosus allatostatin A receptor 0.0012 0.0029 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.1159
Entamoeba histolytica deoxycytidyl transferase, putative 0.0012 0.0034 0.0488
Onchocerca volvulus 0.0012 0.0035 0.0054
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0022 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0158 0.0347
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0018 0.0086 0.0172
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.01 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0142 0.0309
Mycobacterium ulcerans lipase LipD 0.0025 0.0158 0.5393
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0029 0.0029
Brugia malayi hypothetical protein 0.0012 0.0034 0.0048
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0022 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0309
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0936 0.6281
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0069 0.0115
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0029 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.0038 0.0282 0.0282
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0022 0.0001
Echinococcus multilocularis Chromo domain 0.0011 0.0022 0.0007
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0012 0.003 0.0228
Echinococcus multilocularis transient receptor potential ion channel A 0.0137 0.1254 0.1242
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0221 0.2084 0.5014
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0069 0.0115
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0158 0.5625
Loa Loa (eye worm) hypothetical protein 0.0025 0.0158 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0142 0.0309
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0766 0.0752
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0142 0.0309
Echinococcus multilocularis lamin dm0 0.0048 0.0381 0.0367
Mycobacterium tuberculosis Probable hydrolase 0.0025 0.0158 0.0888
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0142 0.0309
Brugia malayi orphan nuclear receptor NR2E1 0.0011 0.0022 0.0017
Brugia malayi G protein-coupled receptor 0.0012 0.0029 0.0036
Echinococcus multilocularis dnaJ subfamily B 0.0872 0.8472 0.847
Brugia malayi Isocitrate dehydrogenase 0.0012 0.003 0.0036
Echinococcus granulosus sodium:hydrogen exchanger 0.0045 0.0354 0.0339
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0018 0.0086 0.1871
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0029 0.0015
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0069 0.0115
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0034 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0029 0.0029
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0029 0.0015
Echinococcus multilocularis sodium:hydrogen exchanger 0.0045 0.0354 0.0339
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0029 0.0029
Echinococcus multilocularis thyroid hormone receptor alpha 0.0147 0.1351 0.1338
Mycobacterium ulcerans hypothetical protein 0.0025 0.0158 0.5393
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0012 0.0034 0.0488
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0029 0.0015
Onchocerca volvulus 0.0098 0.0874 0.3403
Echinococcus multilocularis sodium:hydrogen exchanger 0.0045 0.0354 0.0339
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0142 0.0142
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0158 0.5618
Brugia malayi Calcitonin receptor-like protein seb-1 0.0271 0.257 0.6193
Plasmodium falciparum amino acid transporter, putative 0.0038 0.0282 0.765
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0609 0.1441
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0416 0.3992 0.3983
Loa Loa (eye worm) hypothetical protein 0.0045 0.0354 0.0821
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0022 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0022 0.0017
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0069 0.0115
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0045 0.0354 0.0339
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0036
Trichomonas vaginalis esterase, putative 0.0025 0.0158 0.5618
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0022 0.0018
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0022 0.0022
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0029 0.0029
Brugia malayi ecdysone receptor 0.0011 0.0022 0.0017

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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