Detailed information for compound 81571

Basic information

Technical information
  • TDR Targets ID: 81571
  • Name: methyl 3-[2-phenyl-4-[(3-sulfanylphenyl)methy lamino]phenyl]benzoate
  • MW: 425.542 | Formula: C27H23NO2S
  • H donors: 1 H acceptors: 1 LogP: 6.66 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1cccc(c1)c1ccc(cc1c1ccccc1)NCc1cccc(c1)S
  • InChi: 1S/C27H23NO2S/c1-30-27(29)22-11-6-10-21(16-22)25-14-13-23(17-26(25)20-8-3-2-4-9-20)28-18-19-7-5-12-24(31)15-19/h2-17,28,31H,18H2,1H3
  • InChiKey: BTHZULPQBZZWQC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[4-[(3-mercaptophenyl)methylamino]-2-phenylphenyl]benzoic acid methyl ester
  • 3-[4-[(3-mercaptobenzyl)amino]-2-phenyl-phenyl]benzoic acid methyl ester

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens protein geranylgeranyltransferase type I, beta subunit Starlite/ChEMBL References
Homo sapiens farnesyltransferase, CAAX box, alpha Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium knowlesi protein farnesyltransferase subunit alpha, putative Get druggable targets OG5_128459 All targets in OG5_128459
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein Get druggable targets OG5_128459 All targets in OG5_128459
Echinococcus granulosus protein farnesyltransferase alpha subunit Get druggable targets OG5_128459 All targets in OG5_128459
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit Get druggable targets OG5_129786 All targets in OG5_129786
Giardia lamblia Rab geranylgeranyltransferase Get druggable targets OG5_128459 All targets in OG5_128459
Candida albicans beta subunit of C terminal CaaX Geranylgeranyltransferase I (Ram2p+Cdc43p) Get druggable targets OG5_129786 All targets in OG5_129786
Cryptosporidium parvum farnesyltransferase Get druggable targets OG5_128459 All targets in OG5_128459
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein Get druggable targets OG5_128459 All targets in OG5_128459
Babesia bovis protein prenyltransferase alpha subunit repeat domain containing protein Get druggable targets OG5_128459 All targets in OG5_128459
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_129786 All targets in OG5_129786
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium berghei protein farnesyltransferase subunit alpha, putative Get druggable targets OG5_128459 All targets in OG5_128459
Candida albicans beta subunit of C terminal CaaX Geranylgeranyltransferase I (Ram2p+Cdc43p) Get druggable targets OG5_129786 All targets in OG5_129786
Schistosoma japonicum ko:K05954 farnesyltransferase, CAAX box, alpha [EC:2.5.1.58 2.5.1.59], putative Get druggable targets OG5_128459 All targets in OG5_128459
Schistosoma mansoni geranylgeranyl transferase type I beta subunit Get druggable targets OG5_129786 All targets in OG5_129786
Schistosoma mansoni protein farnesyltransferase alpha subunit Get druggable targets OG5_128459 All targets in OG5_128459
Echinococcus multilocularis protein farnesyltransferase alpha subunit Get druggable targets OG5_128459 All targets in OG5_128459
Candida albicans alpha subunit shared by C terminal CaaX Geranylgeranyltransferase I (Ram2p+Cdc43p) and farnesyltransferase (Ram2p+Ram1p) Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative Get druggable targets OG5_129786 All targets in OG5_129786
Theileria parva hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Schistosoma mansoni geranylgeranyl transferase type I beta subunit Get druggable targets OG5_129786 All targets in OG5_129786
Schistosoma japonicum ko:K05955 protein geranylgeranyltransferase type I, beta subunit [EC:2.5.1.59], putative Get druggable targets OG5_129786 All targets in OG5_129786
Entamoeba histolytica geranylgeranyl transferase beta subunit Get druggable targets OG5_129786 All targets in OG5_129786
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium falciparum protein farnesyltransferase subunit alpha Get druggable targets OG5_128459 All targets in OG5_128459
Toxoplasma gondii hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_129786 All targets in OG5_129786
Cryptosporidium hominis farnesyltransferase Get druggable targets OG5_128459 All targets in OG5_128459
Echinococcus granulosus geranylgeranyl transferase type I beta subunit Get druggable targets OG5_129786 All targets in OG5_129786
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Neospora caninum hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium vivax prenyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Candida albicans alpha subunit shared by C terminal CaaX Geranylgeranyltransferase I (Ram2p+Cdc43p) and farnesyltransferase (Ram2p+Ram1p) Get druggable targets OG5_128459 All targets in OG5_128459
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei protein farnesyltransferase beta subunit protein geranylgeranyltransferase type I, beta subunit 377 aa 361 aa 26.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Loa Loa (eye worm) hypothetical protein 0.0856 0.1578 0.5027
Brugia malayi hypothetical protein 0.0069 0.0025 0.0137
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.038 0.0639 0.3502
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Schistosoma mansoni hypothetical protein 0.038 0.0639 0.0639
Brugia malayi Latrophilin receptor protein 2 0.0237 0.0355 0.1948
Echinococcus multilocularis nmda type glutamate receptor 0.0118 0.0121 0.015
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0454 0.4855
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0221 0.0325 0.1034
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0394 0.0666 0.0826
Loa Loa (eye worm) hypothetical protein 0.0077 0.004 0.0128
Loa Loa (eye worm) tubulin beta-1 chain 0.0067 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0077 0.004 0.0128
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Echinococcus granulosus rhodopsin orphan GPCR 0.038 0.0639 0.0792
Schistosoma mansoni rhodopsin-like orphan GPCR 0.038 0.0639 0.0639
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0131 0.0147 0.0183
Brugia malayi putative neuropeptide receptor NPR1 0.038 0.0639 0.3502
Echinococcus granulosus nAChR subunit 0.0077 0.004 0.005
Loa Loa (eye worm) tubulin beta-2A chain 0.0067 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0085 0.0056 0.5
Loa Loa (eye worm) PAN domain-containing protein 0.0139 0.0162 0.0516
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0131 0.0147 0.0183
Echinococcus multilocularis voltage dependent calcium channel 0.0164 0.0212 0.0262
Mycobacterium ulcerans hypothetical protein 0.0108 0.0101 0.0925
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0143 0.017 0.0211
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0118 0.0121 0.0917
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0066 0.0018 0.0099
Echinococcus granulosus fmrfamide receptor 0.038 0.0639 0.0792
Brugia malayi tailless protein 0.0062 0.001 0.0056
Loa Loa (eye worm) bone morphogenic protein 6 0.014 0.0165 0.0525
Echinococcus granulosus dro:myosuppressin receptor 0.038 0.0639 0.0792
Echinococcus granulosus tm gpcr rhodopsin 0.038 0.0639 0.0792
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0079 0.0043 0.062
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0182 0.0248 0.2649
Schistosoma mansoni neuropeptide receptor 0.038 0.0639 0.0639
Echinococcus granulosus integrin alpha ps 0.0133 0.015 0.0186
Mycobacterium leprae conserved hypothetical protein 0.0335 0.0549 0.5
Trypanosoma brucei calpain, putative 0.0118 0.0121 0.0917
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0079 0.0043 0.0053
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0131 0.0147 0.0183
Echinococcus multilocularis rhodopsin orphan GPCR 0.038 0.0639 0.0792
Echinococcus multilocularis orexin receptor type 2 0.038 0.0639 0.0792
Onchocerca volvulus 0.0108 0.0101 0.0323
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.028 0.2987
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus granulosus Tubulin beta 2C chain 0.0067 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus multilocularis integrin alpha ps 0.0064 0.0014 0.0017
Echinococcus multilocularis neuropeptides capa receptor 0.038 0.0639 0.0792
Echinococcus granulosus tubulin beta 4A class IVa 0.0067 0.0019 0.0024
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0143 0.017 0.0211
Echinococcus granulosus tm gpcr rhodopsin 0.4142 0.8067 1
Echinococcus granulosus neuropeptides capa receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0139 0.0162 0.0516
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0143 0.017 0.0934
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.038 0.0639 0.0639
Echinococcus multilocularis SWI:SNF matrix associated 0.0221 0.0325 0.0402
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.038 0.0639 0.0639
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0118 0.0121 0.1735
Onchocerca volvulus 0.0066 0.0018 0.0057
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0133 0.015 0.0186
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0221 0.0325 0.0402
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0043 0.0328
Loa Loa (eye worm) hypothetical protein 0.0139 0.0162 0.0516
Echinococcus multilocularis glycine receptor subunit beta 0.0143 0.017 0.0211
Schistosoma mansoni steroid hormone receptor ad4bp 0.0131 0.0147 0.0147
Onchocerca volvulus 0.0459 0.0795 0.2533
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.038 0.0639 0.0792
Schistosoma mansoni hypothetical protein 0.0237 0.0355 0.0355
Echinococcus granulosus adenylate cyclase type IX 0.0081 0.0048 0.006
Onchocerca volvulus 0.0108 0.0101 0.0323
Echinococcus granulosus glycine receptor subunit alpha 1 0.0143 0.017 0.0211
Loa Loa (eye worm) nuclear hormone receptor 0.0062 0.001 0.0033
Echinococcus multilocularis integrin alpha ps 0.0133 0.015 0.0186
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0066 0.0018 0.0099
Brugia malayi ORL1-like opioid receptor 0.038 0.0639 0.3502
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0285 0.045 0.0557
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0079 0.0043 0.0053
Onchocerca volvulus 0.038 0.0639 0.2035
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0091 0.0067 0.0084
Toxoplasma gondii ran binding protein 0.0079 0.0043 0.0104
Toxoplasma gondii microneme protein MIC17B 0.0139 0.0162 0.0391
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0193 0.0269 0.287
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0131 0.0147 0.0808
Schistosoma mansoni neurotransmitter gated ion channel 0.0066 0.0018 0.0018
Chlamydia trachomatis DNA topoisomerase I 0.0221 0.0325 1
Loa Loa (eye worm) hypothetical protein 0.0131 0.0147 0.047
Schistosoma mansoni alpha-1 adrenergic receptor 0.038 0.0639 0.0639
Toxoplasma gondii PAN domain-containing protein 0.2159 0.4151 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0131 0.0147 0.0808
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0118 0.0121 0.1003
Echinococcus granulosus serotonin receptor 0.038 0.0639 0.0792
Brugia malayi nuclear hormone receptor 0.0062 0.001 0.0056
Schistosoma mansoni amine GPCR 0.038 0.0639 0.0639
Schistosoma mansoni rhodopsin-like orphan GPCR 0.038 0.0639 0.0639
Brugia malayi hypothetical protein 0.038 0.0639 0.3502
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Brugia malayi hypothetical protein 0.0108 0.0101 0.0556
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0143 0.017 0.0934
Schistosoma mansoni tubulin subunit beta 0.0067 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.065 0.1171 0.373
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0131 0.0147 0.047
Echinococcus multilocularis Mastin 0.0108 0.0101 0.0126
Trypanosoma brucei RNA helicase, putative 0.0723 0.1316 1
Schistosoma mansoni tubulin subunit beta 0.0067 0.0019 0.0019
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0193 0.0269 0.287
Echinococcus multilocularis fmrfamide receptor 0.038 0.0639 0.0792
Echinococcus granulosus beta tubulin 0.0067 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Brugia malayi neuropeptide F receptor 0.038 0.0639 0.3502
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0143 0.017 0.017
Echinococcus granulosus zinc finger protein Ran binding 0.0079 0.0043 0.0053
Onchocerca volvulus 0.0139 0.0162 0.0516
Onchocerca volvulus 0.0139 0.0162 0.0516
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Onchocerca volvulus 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0131 0.0146 0.0465
Schistosoma mansoni neurotransmitter gated ion channel 0.0066 0.0018 0.0018
Onchocerca volvulus 0.0143 0.017 0.0543
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0164 0.0212 0.0262
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0143 0.017 0.0543
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0115 0.0115 0.0368
Brugia malayi nuclear receptor NHR-67 0.0062 0.001 0.0056
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0542 0.0958 0.1187
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Leishmania major beta tubulin 0.0067 0.0019 0.016
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0143 0.017 0.0211
Echinococcus granulosus Mastin 0.0108 0.0101 0.0126
Toxoplasma gondii hypothetical protein 0.0139 0.0162 0.0391
Echinococcus multilocularis ephrin type A receptor 4 A 0.026 0.0401 0.0497
Echinococcus granulosus deoxyribonuclease ii 0.0072 0.0031 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0131 0.0147 0.047
Brugia malayi Trypsin-like protease protein 5 0.0108 0.0101 0.0556
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0131 0.0147 0.0147
Schistosoma mansoni nuclear receptor nhr-48 0.0062 0.001 0.001
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0143 0.017 0.0934
Onchocerca volvulus 0.0459 0.0795 0.2533
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0108 0.0101 0.0126
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Schistosoma mansoni fusion 0.0079 0.0043 0.0043
Onchocerca volvulus 0.038 0.0639 0.2035
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0164 0.0212 0.0212
Schistosoma mansoni tubulin subunit beta 0.0067 0.0019 0.0019
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.038 0.0639 0.0639
Echinococcus multilocularis neuropeptide s receptor 0.084 0.1547 0.1918
Onchocerca volvulus Bile acid receptor homolog 0.0131 0.0147 0.047
Echinococcus granulosus rhodopsin orphan GPCR 0.038 0.0639 0.0792
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0085 0.0056 0.5
Echinococcus granulosus g protein coupled receptor 0.038 0.0639 0.0792
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0666 0.1204 1
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0193 0.0269 0.0333
Echinococcus granulosus Tubulin beta 2C chain 0.0067 0.0019 0.0024
Trypanosoma cruzi beta tubulin, putative 0.0067 0.0019 0.0278
Trypanosoma brucei hypothetical protein 0.0118 0.0121 0.0917
Loa Loa (eye worm) hypothetical protein 0.1646 0.3139 1
Onchocerca volvulus 0.038 0.0639 0.2035
Loa Loa (eye worm) integrin alpha pat-2 0.0457 0.0791 0.2519
Onchocerca volvulus 0.0108 0.0101 0.0323
Echinococcus granulosus Tubulin beta 2C chain 0.0067 0.0019 0.0024
Trypanosoma brucei C-8 sterol isomerase, putative 0.0409 0.0696 0.5288
Brugia malayi Dopamine receptor protein 2 0.038 0.0639 0.3502
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0143 0.017 0.0934
Echinococcus granulosus g protein coupled receptor 0.038 0.0639 0.0792
Leishmania major beta tubulin 0.0067 0.0019 0.016
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0164 0.0212 0.0262
Echinococcus granulosus 7TM GPCR rhodopsin 0.038 0.0639 0.0792
Onchocerca volvulus 0.038 0.0639 0.2035
Toxoplasma gondii hypothetical protein 0.0107 0.0099 0.0239
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Loa Loa (eye worm) hypothetical protein 0.0069 0.0025 0.0079
Echinococcus granulosus tachykinin peptides receptor 99D 0.038 0.0639 0.0792
Echinococcus granulosus enteropeptidase 0.0108 0.0101 0.0126
Onchocerca volvulus 0.038 0.0639 0.2035
Brugia malayi G-protein coupled receptor 0.038 0.0639 0.3502
Schistosoma mansoni myosin xvIII 0.038 0.0639 0.0639
Onchocerca volvulus 0.0139 0.0162 0.0516
Schistosoma mansoni furin-1 (S08 family) 0.0365 0.0609 0.0609
Schistosoma mansoni amine GPCR 0.038 0.0639 0.0639
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus granulosus anti dorsalizing morphogenetic protein 1a 0.014 0.0165 0.0204
Brugia malayi Serotonin receptor 0.038 0.0639 0.3502
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0131 0.0147 0.0808
Brugia malayi Angiotensin-converting enzyme family protein 0.0165 0.0213 0.1168
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0143 0.017 0.0211
Echinococcus multilocularis thyroid hormone receptor alpha 0.0131 0.0147 0.0183
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0118 0.0121 0.0917
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.038 0.0639 0.0639
Onchocerca volvulus 0.0139 0.0162 0.0516
Echinococcus multilocularis neuropeptide receptor 0.038 0.0639 0.0792
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0143 0.017 0.0211
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Onchocerca volvulus 0.0139 0.0162 0.0516
Loa Loa (eye worm) hypothetical protein 0.0077 0.004 0.0128
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.026 0.2773
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0131 0.0147 0.047
Loa Loa (eye worm) hypothetical protein 0.0224 0.0331 0.1054
Echinococcus multilocularis Furin 1 0.0223 0.0327 0.0406
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.024 0.0362 0.0449
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.038 0.0639 0.3502
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0118 0.0121 0.0917
Brugia malayi nuclear receptor RXR 0.0062 0.001 0.0056
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0118 0.0121 0.1735
Brugia malayi phosphoinositide-dependent protein kinase I 0.0102 0.0089 0.0491
Chlamydia trachomatis SWIB complex protein 0.0221 0.0325 1
Onchocerca volvulus 0.0066 0.0018 0.0057
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0062 0.001 0.0033
Schistosoma mansoni hypothetical protein 0.0108 0.0101 0.0101
Brugia malayi photoreceptor-specific nuclear receptor 0.0131 0.0147 0.0808
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0091 0.0067 0.0084
Onchocerca volvulus 0.0143 0.017 0.0543
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.038 0.0639 0.0792
Schistosoma mansoni opsin-like receptor 0.038 0.0639 0.0639
Trypanosoma cruzi WLM domain containing protein, putative 0.0079 0.0043 0.062
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0143 0.017 0.0934
Onchocerca volvulus 0.0062 0.001 0.0033
Echinococcus multilocularis alpha 1A adrenergic receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0064 0.0014 0.0043
Brugia malayi Cation transporter family protein 0.0459 0.0795 0.4358
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0102 0.0089 0.0111
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0143 0.017 0.0934
Trypanosoma brucei beta tubulin 0.0067 0.0019 0.0147
Echinococcus multilocularis serotonin receptor 0.038 0.0639 0.0792
Brugia malayi hypothetical protein 0.0586 0.1044 0.5723
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0066 0.0018 0.0099
Loa Loa (eye worm) hypothetical protein 0.0409 0.0696 0.2216
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0066 0.0018 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.038 0.0639 0.0639
Schistosoma mansoni adenoreceptor 0.038 0.0639 0.0639
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0285 0.045 0.2465
Leishmania major beta tubulin 0.0067 0.0019 0.016
Brugia malayi Nuclear hormone receptor-like 1 0.0131 0.0147 0.0808
Loa Loa (eye worm) GABA receptor subunit 0.0077 0.004 0.0128
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Echinococcus multilocularis somatostatin receptor 0.038 0.0639 0.0792
Echinococcus multilocularis Tubulin beta 2C chain 0.0067 0.0019 0.0024
Toxoplasma gondii PAN domain-containing protein 0.0139 0.0162 0.0391
Schistosoma mansoni protein kinase 0.0133 0.015 0.015
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0143 0.017 0.0934
Leishmania major hypothetical protein, conserved 0.0079 0.0043 0.0358
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0285 0.045 0.0557
Schistosoma mansoni nuclear receptor 0.0062 0.001 0.001
Echinococcus multilocularis dro:myosuppressin receptor 0.038 0.0639 0.0792
Brugia malayi hypothetical protein 0.0071 0.0029 0.0158
Schistosoma mansoni coup transcription factor 0.0131 0.0147 0.0147
Echinococcus multilocularis rhodopsin orphan GPCR 0.038 0.0639 0.0792
Leishmania major hypothetical protein, conserved 0.0079 0.0043 0.0358
Loa Loa (eye worm) hypothetical protein 0.0393 0.0665 0.2118
Onchocerca volvulus 0.0542 0.0957 0.3049
Brugia malayi Serotonin receptor 0.038 0.0639 0.3502
Schistosoma mansoni nAChR subunit 0.0143 0.017 0.017
Toxoplasma gondii microneme protein MIC17A 0.0139 0.0162 0.0391
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.016 0.0204 0.065
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0143 0.017 0.0211
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0143 0.017 0.0211
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0118 0.0121 0.1735
Loa Loa (eye worm) hypothetical protein 0.0459 0.0795 0.2533
Brugia malayi hypothetical protein 0.0062 0.001 0.0056
Schistosoma mansoni nAChR subunit 0.0143 0.017 0.017
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0285 0.045 0.1432
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0223 0.0327 0.35
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0131 0.0147 0.0147
Schistosoma mansoni growth hormone secretagogue receptor 0.038 0.0639 0.0639
Onchocerca volvulus 0.0083 0.0052 0.0166
Echinococcus multilocularis Tubulin beta 2C chain 0.0067 0.0019 0.0024
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) brahma associated protein 0.0221 0.0325 0.1034
Onchocerca volvulus 0.038 0.0639 0.2035
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0069 0.0025 0.0079
Loa Loa (eye worm) voltage-dependent calcium channel 0.0164 0.0212 0.0674
Leishmania major beta tubulin 0.0067 0.0019 0.016
Brugia malayi brahma associated protein 60 kDa 0.0221 0.0325 0.1779
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Brugia malayi putative neuropeptide receptor 0.038 0.0639 0.3502
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0287 0.0454 0.1447
Toxoplasma gondii hypothetical protein 0.0143 0.017 0.0409
Onchocerca volvulus 0.0139 0.0162 0.0516
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0066 0.0018 0.0057
Toxoplasma gondii beta-tubulin, putative 0.0067 0.0019 0.0047
Brugia malayi hypothetical protein 0.0066 0.0018 0.0099
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0043 0.062
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Echinococcus multilocularis neuroendocrine convertase 2 0.0548 0.097 0.1202
Echinococcus granulosus beta tubulin 0.0067 0.0019 0.0024
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.038 0.0639 0.0639
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0131 0.0147 0.0183
Brugia malayi neuroendocrine convertase 1 precursor 0.0548 0.097 0.5315
Leishmania major beta tubulin 0.0067 0.0019 0.016
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0089 0.0089
Mycobacterium tuberculosis Conserved protein 0.0335 0.0549 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0131 0.0147 0.0183
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Leishmania major beta tubulin 0.0067 0.0019 0.016
Schistosoma mansoni hypothetical protein 0.0074 0.0034 0.0034
Onchocerca volvulus 0.0139 0.0162 0.0516
Giardia lamblia Furin precursor putative serine protease 0.0182 0.0248 0.4795
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0062 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0079 0.0043 0.0236
Loa Loa (eye worm) hypothetical protein 0.0158 0.0199 0.0634
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0981 0.1824 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0101 0.0323
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0131 0.0147 0.0183
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0285 0.045 0.0557
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.024 0.0362 0.1985
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0143 0.017 0.0934
Loa Loa (eye worm) deoxyribonuclease II family protein 0.0072 0.0031 0.0097
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0237 0.0355 0.044
Onchocerca volvulus 0.038 0.0639 0.2035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.038 0.0639 0.0639
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Onchocerca volvulus 0.038 0.0639 0.2035
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0221 0.0325 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0212 0.0674
Onchocerca volvulus 0.0139 0.0162 0.0516
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.038 0.0639 0.2035
Onchocerca volvulus 0.038 0.0639 0.2035
Echinococcus multilocularis calcium activated potassium channel 0.0059 0.0003 0.0004
Trypanosoma brucei beta tubulin 0.0067 0.0019 0.0147
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0193 0.0269 0.0856
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0223 0.0327 0.35
Echinococcus multilocularis serotonin receptor 0.038 0.0639 0.0792
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0066 0.0018 0.0022
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0325 0.053 0.1688
Echinococcus granulosus voltage dependent calcium channel 0.0164 0.0212 0.0262
Trichomonas vaginalis conserved hypothetical protein 0.0221 0.0325 0.3468
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0131 0.0147 0.0183
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0079 0.0043 0.0053
Echinococcus multilocularis nAChR subunit 0.0077 0.004 0.005
Loa Loa (eye worm) hypothetical protein 0.0459 0.0795 0.2533
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0131 0.0147 0.0808
Echinococcus granulosus neuroendocrine convertase 2 0.0548 0.097 0.1202
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Echinococcus multilocularis G-protein coupled receptor, putative 0.038 0.0639 0.0792
Echinococcus multilocularis g protein coupled receptor 0.038 0.0639 0.0792
Toxoplasma gondii hypothetical protein 0.0139 0.0162 0.0391
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0143 0.017 0.0934
Schistosoma mansoni hypothetical protein 0.0439 0.0754 0.0754
Brugia malayi Serotonin/octopamine receptor family protein 7 0.038 0.0639 0.3502
Brugia malayi hypothetical protein 0.038 0.0639 0.3502
Echinococcus multilocularis transmembrane protease serine 3 0.0108 0.0101 0.0126
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.001 0.0013
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0182 0.0248 0.2649
Echinococcus multilocularis neuropeptides capa receptor 0.038 0.0639 0.0792
Echinococcus granulosus Tubulin beta 2C chain 0.0067 0.0019 0.0024
Echinococcus granulosus neuropeptide FF receptor 2 0.0853 0.1572 0.1948
Echinococcus granulosus hypothetical protein 0.038 0.0639 0.0792
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0077 0.004 0.022
Leishmania major C-8 sterol isomerase-like protein 0.0409 0.0696 0.578
Loa Loa (eye worm) hypothetical protein 0.065 0.1171 0.373
Brugia malayi Trypsin family protein 0.0108 0.0101 0.0556
Brugia malayi Cation transporter family protein 0.0143 0.017 0.0934
Trichomonas vaginalis tubulin epsilon chain, putative 0.0067 0.0019 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0131 0.0147 0.0808
Onchocerca volvulus 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Brugia malayi GnHR receptor homolog 0.038 0.0639 0.3502
Toxoplasma gondii transporter, cation channel family protein 0.0164 0.0212 0.051
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0221 0.0325 1
Schistosoma mansoni neuropeptide f receptor 76f 0.038 0.0639 0.0639
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.038 0.0639 0.0639
Echinococcus granulosus furin 0.0856 0.1578 0.1956
Brugia malayi hypothetical protein 0.038 0.0639 0.3502
Schistosoma mansoni hypothetical protein 0.0108 0.0101 0.0101
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0665 0.12 0.12
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0237 0.0355 0.044
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0143 0.017 0.0543
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.038 0.0639 0.0639
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0077 0.004 0.004
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0077 0.004 0.022
Echinococcus granulosus FTZ F1 alpha 0.0131 0.0147 0.0183
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Brugia malayi endoprotease bli-4 precursor 0.0856 0.1578 0.8649
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Trichomonas vaginalis DNAse2-prov protein, putative 0.0072 0.0031 0.0326
Echinococcus granulosus rhodopsin orphan GPCR 0.038 0.0639 0.0792
Brugia malayi nuclear hormone receptor family member nhr-6 0.0062 0.001 0.0056
Schistosoma mansoni RNA binding protein 0.0079 0.0043 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0237 0.0355 0.1132
Loa Loa (eye worm) hypothetical protein 0.0108 0.0101 0.0323
Brugia malayi Protein kinase domain containing protein 0.0102 0.0089 0.0491
Schistosoma mansoni TRABID protein (C64 family) 0.0079 0.0043 0.0043
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus multilocularis beta tubulin 0.0067 0.0019 0.0024
Schistosoma mansoni integrin alpha-ps 0.0069 0.0024 0.0024
Leishmania major beta tubulin 0.0067 0.0019 0.016
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0079 0.0043 0.0328
Schistosoma mansoni biogenic amine (dopamine) receptor 0.038 0.0639 0.0639
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0077 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0165 0.0213 0.0679
Brugia malayi ecdysteroid receptor 0.0131 0.0147 0.0808
Brugia malayi latrophilin 2 splice variant baaae 0.0439 0.0754 0.4134
Loa Loa (eye worm) hypothetical protein 0.0164 0.0212 0.0674
Echinococcus multilocularis allatostatin A receptor 0.1646 0.3139 0.3891
Brugia malayi Steroid receptor seven-up type 2 0.0131 0.0147 0.0808
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.024 0.0362 0.3871
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.026 0.2773
Brugia malayi larval opioid receptor 0.038 0.0639 0.3502
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.038 0.0639 0.2035
Brugia malayi Dopamine receptor 0.038 0.0639 0.3502
Echinococcus multilocularis integrin alpha ps 0.0133 0.015 0.0186
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0454 0.4855
Schistosoma mansoni nAChR subunit 0.0143 0.017 0.017
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0676 0.1222 0.3892
Schistosoma mansoni nAChR subunit 0.0143 0.017 0.017
Echinococcus multilocularis integrin alpha 3 0.0227 0.0337 0.0417
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.038 0.0639 0.3502
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0089 0.0956
Brugia malayi steroid hormone receptor 0.0131 0.0147 0.0808
Loa Loa (eye worm) calcium channel 0.0164 0.0212 0.0674
Echinococcus granulosus neuropeptide Y receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0184 0.025 0.0797
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0079 0.0043 0.0104
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0118 0.0121 0.1735
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Trichomonas vaginalis deoxyribonuclease II precursor, putative 0.0072 0.0031 0.0326
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0454 0.4855
Schistosoma mansoni hypothetical protein 0.0064 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0077 0.004 0.0128
Echinococcus multilocularis zinc finger protein Ran binding 0.0079 0.0043 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0131 0.0147 0.0808
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.001 0.0033
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0118 0.0121 0.015
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0108 0.0101 0.0126
Loa Loa (eye worm) hypothetical protein 0.0586 0.1044 0.3326
Echinococcus multilocularis ecdysone induced protein 78C 0.0131 0.0147 0.0183
Onchocerca volvulus 0.065 0.1171 0.373
Echinococcus multilocularis rhodopsin orphan GPCR 0.038 0.0639 0.0792
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0143 0.017 0.0211
Loa Loa (eye worm) hypothetical protein 0.0394 0.0666 0.2123
Echinococcus multilocularis beta tubulin 0.0067 0.0019 0.0024
Brugia malayi Caveolin-1 0.0517 0.0908 0.4978
Brugia malayi ecdysone receptor 0.0062 0.001 0.0056
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0118 0.0121 0.0917
Brugia malayi Calcitonin receptor-like protein seb-1 0.0676 0.1222 0.6697
Brugia malayi gonadotropin-releasing hormone receptor 2 0.038 0.0639 0.3502
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.028 0.2987
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.026 0.2773
Echinococcus multilocularis GPCR, family 2 0.0237 0.0355 0.044
Toxoplasma gondii PAN/Apple domain-containing protein 0.0139 0.0162 0.0391
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0164 0.0212 0.3041
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0069 0.0025 0.0031
Echinococcus granulosus Zinc finger RanBP2 type 0.0079 0.0043 0.0053
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0108 0.0101 0.0126
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0139 0.0162 0.0391
Schistosoma mansoni voltage-gated cation channel 0.0164 0.0212 0.0212
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.038 0.0639 0.0639
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Brugia malayi conserved hypotetical protein 0.0062 0.001 0.0056
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0069 0.0025 0.0025
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0079 0.0043 0.062
Schistosoma mansoni integrin alpha-ps 0.0133 0.015 0.015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.001 0.0013
Onchocerca volvulus 0.0139 0.0162 0.0516
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0102 0.0089 0.0285
Trichomonas vaginalis tubulin gamma chain, putative 0.0067 0.0019 0.0206
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0221 0.0325 0.0402
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0221 0.0325 0.0782
Toxoplasma gondii PAN domain-containing protein 0.0139 0.0162 0.0391
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.026 0.2773
Schistosoma mansoni opsin-like receptor 0.038 0.0639 0.0639
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0131 0.0147 0.0183
Loa Loa (eye worm) hypothetical protein 0.0077 0.004 0.0128
Toxoplasma gondii PAN domain-containing protein 0.2159 0.4151 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Loa Loa (eye worm) PAN domain-containing protein 0.0139 0.0162 0.0516
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.026 0.2773
Loa Loa (eye worm) ACC-1 protein 0.0143 0.017 0.0543
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus multilocularis sex peptide receptor 0.038 0.0639 0.0792
Toxoplasma gondii microneme protein MIC17C 0.0139 0.0162 0.0391
Mycobacterium ulcerans hypothetical protein 0.0335 0.0549 1
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0118 0.0121 0.0917
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0164 0.0212 0.116
Schistosoma mansoni protein kinase 0.0133 0.015 0.015
Brugia malayi Nuclear hormone receptor-like 1 0.0069 0.0025 0.0137
Schistosoma mansoni acetylcholine receptor subunit beta 0.0066 0.0018 0.0018
Brugia malayi nuclear receptor NHR-88 0.0062 0.001 0.0056
Schistosoma mansoni nAChR subunit 0.0066 0.0018 0.0018
Echinococcus granulosus glycine receptor subunit beta 0.0143 0.017 0.0211
Echinococcus multilocularis tubulin subunit beta 0.0067 0.0019 0.0024
Echinococcus granulosus g-protein coupled receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) BEN-1 protein 0.0067 0.0019 0.0062
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0193 0.0269 0.1472
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0143 0.017 0.0934
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.038 0.0639 0.0639
Loa Loa (eye worm) G-protein coupled receptor 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0107 0.0099 0.0316
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Onchocerca volvulus 0.0257 0.0395 0.1258
Brugia malayi Nuclear hormone receptor-like 1 0.0069 0.0025 0.0137
Schistosoma mansoni protein kinase 0.0133 0.015 0.015
Leishmania major hypothetical protein, conserved 0.0079 0.0043 0.0358
Loa Loa (eye worm) hypothetical protein 0.0139 0.0162 0.0516
Loa Loa (eye worm) hypothetical protein 0.0069 0.0024 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0131 0.0147 0.0808
Giardia lamblia High cysteine membrane protein Group 2 0.0308 0.0496 1
Trichomonas vaginalis tubulin beta chain, putative 0.0067 0.0019 0.0206
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0079 0.0043 0.062
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0066 0.0018 0.0099
Echinococcus granulosus neuropeptide receptor 0.038 0.0639 0.0792
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0062 0.001 0.001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.038 0.0639 0.2035
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0079 0.0043 0.062
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Loa Loa (eye worm) acetylcholine receptor protein 0.0066 0.0018 0.0057
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0079 0.0043 0.0137
Echinococcus granulosus glycine receptor subunit alpha 1 0.0143 0.017 0.0211
Trypanosoma brucei beta tubulin 0.0067 0.0019 0.0147
Schistosoma mansoni neuropeptide receptor 0.038 0.0639 0.0639
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Echinococcus multilocularis sodium channel protein 0.0666 0.1204 0.1492
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0131 0.0147 0.0147
Trichomonas vaginalis tubulin alpha chain, putative 0.0067 0.0019 0.0206
Echinococcus granulosus ephrin type A receptor 4 A 0.026 0.0401 0.0497
Loa Loa (eye worm) hypothetical protein 0.0209 0.0301 0.0958
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0143 0.017 0.0211
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0079 0.0043 0.0328
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0131 0.0147 0.0808
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.024 0.0362 0.0449
Echinococcus multilocularis epidermal growth factor receptor 0.0137 0.0158 0.0196
Brugia malayi Melatonin receptor type 1A 0.038 0.0639 0.3502
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0043 0.062
Echinococcus granulosus calcium activated potassium channel 0.0059 0.0003 0.0004
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0285 0.045 0.0557
Brugia malayi nuclear receptor RXR 0.0069 0.0025 0.0137
Brugia malayi hypothetical protein 0.0066 0.0018 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Echinococcus granulosus 7tm_1 domain containing protein 0.038 0.0639 0.0792
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0131 0.0147 0.0147
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0193 0.0269 0.8168
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.038 0.0639 0.2035
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0131 0.0147 0.0183
Leishmania major beta tubulin 0.0067 0.0019 0.016
Loa Loa (eye worm) hypothetical protein 0.0981 0.1824 0.5812
Schistosoma mansoni hypothetical protein 0.038 0.0639 0.0639
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0143 0.017 0.0934
Onchocerca volvulus 0.038 0.0639 0.2035
Echinococcus multilocularis adenylate cyclase 9 0.0058 0.0002 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.038 0.0639 0.0639
Brugia malayi nuclear hormone receptor family member odr-7 0.0062 0.001 0.0056
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0164 0.0212 0.0262
Schistosoma mansoni tyrosine kinase 0.0137 0.0158 0.0158
Loa Loa (eye worm) endoprotease bli-4 0.0856 0.1578 0.5027
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0043 0.0328
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0193 0.0269 0.8168
Loa Loa (eye worm) proprotein convertase 2 0.0223 0.0327 0.1043
Onchocerca volvulus Putative nachr subunit 0.0285 0.045 0.1432
Schistosoma mansoni rhodopsin-like orphan GPCR 0.038 0.0639 0.0639
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0285 0.045 0.0557
Loa Loa (eye worm) hypothetical protein 0.0079 0.0043 0.0137
Echinococcus granulosus sex peptide receptor 0.038 0.0639 0.0792
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.038 0.0639 0.0792
Onchocerca volvulus 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0058 0.0002 0.0006
Echinococcus granulosus allatostatin A receptor 0.1646 0.3139 0.3891
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Loa Loa (eye worm) hypothetical protein 0.0079 0.0043 0.0137
Onchocerca volvulus 0.0079 0.0043 0.0137
Brugia malayi hypothetical protein 0.038 0.0639 0.3502
Echinococcus multilocularis g protein coupled receptor 0.038 0.0639 0.0792
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.026 0.2773
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0066 0.0018 0.0022
Onchocerca volvulus 0.0459 0.0795 0.2533
Onchocerca volvulus 0.0071 0.0029 0.0092
Onchocerca volvulus Protein ultraspiracle homolog 0.0131 0.0147 0.047
Schistosoma mansoni apoptosis regulator bax 0.0394 0.0666 0.0666
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.038 0.0639 0.0792
Toxoplasma gondii PAN domain-containing protein 0.0139 0.0162 0.0391
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Trypanosoma cruzi WLM domain containing protein, putative 0.0079 0.0043 0.062
Brugia malayi hypothetical protein 0.0066 0.0018 0.0099
Echinococcus multilocularis enteropeptidase 0.0108 0.0101 0.0126
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0089 0.0956
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0223 0.0327 0.0327
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0182 0.0248 0.2649
Echinococcus granulosus rhodopsin orphan GPCR 0.038 0.0639 0.0792
Brugia malayi hypothetical protein 0.038 0.0639 0.3502
Brugia malayi hypothetical protein 0.0066 0.0018 0.0099
Onchocerca volvulus 0.0221 0.0325 0.1034
Schistosoma mansoni nuclear receptor 0.0062 0.001 0.001
Trichomonas vaginalis hypothetical protein 0.0182 0.0248 0.2649
Onchocerca volvulus Neuropeptide F receptor homolog 0.038 0.0639 0.2035
Schistosoma mansoni histamine h1 receptor 0.038 0.0639 0.0639
Echinococcus granulosus nuclear receptor nhr 48 0.0062 0.001 0.0013
Loa Loa (eye worm) steroid hormone receptor 0.0131 0.0147 0.047
Schistosoma mansoni hypothetical protein 0.0221 0.0325 0.0325
Mycobacterium ulcerans hypothetical protein 0.0335 0.0549 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0223 0.0327 0.35
Schistosoma mansoni biogenic amine (5HT) receptor 0.038 0.0639 0.0639
Echinococcus multilocularis fmrfamide receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0139 0.0162 0.0516
Echinococcus multilocularis rhodopsin orphan GPCR 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0459 0.0795 0.0795
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0102 0.0089 0.0111
Loa Loa (eye worm) hypothetical protein 0.0139 0.0162 0.0516
Onchocerca volvulus 0.0108 0.0101 0.0323
Schistosoma mansoni ephrin receptor 0.026 0.0401 0.0401
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0079 0.0043 0.0236
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0223 0.0327 0.35
Loa Loa (eye worm) BEN-1 protein 0.0067 0.0019 0.0062
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0164 0.0212 0.0262
Onchocerca volvulus Glucosylceramidase homolog 0.0188 0.026 0.0827
Brugia malayi neuropeptide F receptor 0.038 0.0639 0.3502
Schistosoma mansoni nAChR subunit 0.0066 0.0018 0.0018
Echinococcus granulosus G protein coupled receptor 139 0.038 0.0639 0.0792
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.038 0.0639 0.0792
Brugia malayi Trypsin family protein 0.065 0.1171 0.6418
Schistosoma mansoni hypothetical protein 0.0221 0.0325 0.0325
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0143 0.017 0.017
Schistosoma mansoni zinc finger protein 0.0079 0.0043 0.0043
Leishmania major beta tubulin 0.0067 0.0019 0.016
Entamoeba histolytica hypothetical protein, conserved 0.0335 0.0549 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0062 0.001 0.0013
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0131 0.0147 0.047
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0454 0.4855
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0069 0.0025 0.0025
Loa Loa (eye worm) PAN domain-containing protein 0.0139 0.0162 0.0516
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0118 0.0121 0.0121
Brugia malayi brahma associated protein 60 kDa 0.0221 0.0325 0.1779
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Brugia malayi Trypsin family protein 0.0108 0.0101 0.0556
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0531 0.0936 0.116
Brugia malayi Furin-like cysteine rich region family protein 0.0137 0.0158 0.0867
Loa Loa (eye worm) TK/EGFR protein kinase 0.0137 0.0158 0.0504
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0221 0.0325 0.0782
Echinococcus granulosus Tubulin beta 2C chain 0.0067 0.0019 0.0024
Brugia malayi YY1-associated factor 2 0.0079 0.0043 0.0236
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0131 0.0147 0.047
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0224 0.0331 0.1813
Brugia malayi hypothetical protein 0.038 0.0639 0.3502
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0069 0.0025 0.0031
Brugia malayi nuclear hormone receptor 0.0131 0.0147 0.0808
Loa Loa (eye worm) deoxyribonuclease II family protein 0.0072 0.0031 0.0097
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.038 0.0639 0.0792
Brugia malayi G protein-coupled receptor F59B2.13 0.038 0.0639 0.3502
Echinococcus granulosus ring and YY1 binding protein 0.0079 0.0043 0.0053
Brugia malayi sulfakinin receptor protein 0.0586 0.1044 0.5723
Echinococcus granulosus alpha 1A adrenergic receptor 0.038 0.0639 0.0792
Leishmania major beta tubulin 0.0067 0.0019 0.016
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0164 0.0212 0.0262
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0131 0.0147 0.0808
Echinococcus granulosus neuropeptides capa receptor 0.038 0.0639 0.0792
Schistosoma mansoni neuropeptide F-like receptor 0.038 0.0639 0.0639
Schistosoma mansoni RAR-like nuclear receptor 0.0131 0.0147 0.0147
Echinococcus granulosus Furin 1 0.0223 0.0327 0.0406
Brugia malayi hypothetical protein 0.038 0.0639 0.3502
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0102 0.0089 0.0285
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0108 0.0101 0.0323
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0133 0.015 0.0186
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0164 0.0212 0.1608
Loa Loa (eye worm) hypothetical protein 0.0069 0.0025 0.0079
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0066 0.0018 0.0022
Onchocerca volvulus 0.0062 0.001 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0131 0.0147 0.0808
Loa Loa (eye worm) hypothetical protein 0.0131 0.0147 0.047
Onchocerca volvulus 0.0079 0.0043 0.0137
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Schistosoma mansoni hypothetical protein 0.0394 0.0666 0.0666
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0108 0.0101 0.0101
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.038 0.0639 0.0792
Brugia malayi bZIP transcription factor family protein 0.0091 0.0067 0.037
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0221 0.0325 1
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0131 0.0147 0.047
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0223 0.0327 0.35
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus granulosus rhodopsin orphan GPCR 0.038 0.0639 0.0792
Echinococcus granulosus rhodopsin orphan GPCR 0.038 0.0639 0.0792
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0062 0.001 0.0056
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.001 0.0013
Loa Loa (eye worm) latrophilin receptor protein 2 0.0237 0.0355 0.1132
Schistosoma mansoni neuropeptide F-like receptor 0.038 0.0639 0.0639
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0164 0.0212 0.0262
Toxoplasma gondii subtilisin SUB12 0.0179 0.0242 0.0582
Schistosoma mansoni amine GPCR 0.038 0.0639 0.0639
Toxoplasma gondii PAN domain-containing protein 0.0139 0.0162 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.038 0.0639 0.0792
Loa Loa (eye worm) neuropeptide F receptor 0.038 0.0639 0.2035
Echinococcus granulosus nmda type glutamate receptor 0.0118 0.0121 0.015
Brugia malayi celfurPC protein 0.0673 0.1218 0.6675
Onchocerca volvulus 0.0077 0.004 0.0128
Echinococcus granulosus nAChR subunit 0.0143 0.017 0.0211
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus multilocularis 0.0673 0.1218 0.1509
Schistosoma mansoni hypothetical protein 0.0079 0.0043 0.0043
Echinococcus granulosus epidermal growth factor receptor 0.0137 0.0158 0.0196
Brugia malayi hypothetical protein 0.0066 0.0018 0.0099
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.026 0.2773
Echinococcus multilocularis glycine receptor subunit beta 0.0143 0.017 0.0211
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0067 0.0019 0.0024
Schistosoma mansoni tubulin subunit beta 0.0067 0.0019 0.0019
Schistosoma mansoni nAChR subunit 0.0143 0.017 0.017
Loa Loa (eye worm) tubulin beta chain 0.0067 0.0019 0.0062
Brugia malayi G-protein coupled receptor 0.038 0.0639 0.3502
Echinococcus multilocularis biogenic amine (5HT) receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) LGC-31 protein 0.0143 0.017 0.0543
Echinococcus granulosus transmembrane protease serine 3 0.0108 0.0101 0.0126
Loa Loa (eye worm) hypothetical protein 0.0131 0.0147 0.047
Schistosoma mansoni nuclear hormone receptor 0.0062 0.001 0.001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0118 0.0121 0.1735
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0193 0.0269 0.0333
Echinococcus granulosus neuropeptide s receptor 0.084 0.1547 0.1918
Schistosoma mansoni thyroid hormone receptor 0.0131 0.0147 0.0147
Brugia malayi Adenylyl cyclase protein 0.0058 0.0002 0.001
Brugia malayi ephrin receptor 1 precursor 0.0124 0.0132 0.0726
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0454 0.4855
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0394 0.0666 0.0666
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0193 0.0269 0.287
Loa Loa (eye worm) nuclear receptor NHR-67 0.0062 0.001 0.0033
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0143 0.017 0.0211
Brugia malayi Nuclear hormone receptor E75 0.0062 0.001 0.0056
Leishmania major beta tubulin 0.0067 0.0019 0.016
Echinococcus granulosus glycine receptor subunit alpha 1 0.0143 0.017 0.0211
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.001 0.0013
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0066 0.0018 0.0099
Brugia malayi AKH receptor 0.038 0.0639 0.3502
Toxoplasma gondii microneme protein, putative 0.0139 0.0162 0.0391
Loa Loa (eye worm) TK/EPH protein kinase 0.033 0.054 0.1719
Schistosoma mansoni zinc finger protein 0.0062 0.001 0.001
Echinococcus multilocularis anti dorsalizing morphogenetic protein 1a 0.014 0.0165 0.0204
Loa Loa (eye worm) hypothetical protein 0.0079 0.0043 0.0137
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0079 0.0043 0.078
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.4142 0.8067 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.0063 0.0199
Loa Loa (eye worm) hypothetical protein 0.0285 0.045 0.1432
Schistosoma mansoni hypothetical protein 0.0237 0.0355 0.0355
Schistosoma mansoni jun-related protein 0.0074 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0531 0.0936 1
Brugia malayi hypothetical protein 0.0062 0.001 0.0056
Trypanosoma brucei beta tubulin 0.0067 0.0019 0.0147
Echinococcus granulosus sodium channel protein 0.0666 0.1204 0.1492
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0101 0.0101
Schistosoma mansoni hypothetical protein 0.0394 0.0666 0.0666
Echinococcus granulosus biogenic amine 5HT receptor 0.038 0.0639 0.0792
Schistosoma mansoni opsin-like receptor 0.038 0.0639 0.0639
Entamoeba histolytica hypothetical protein 0.0077 0.004 0.0392
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Schistosoma mansoni rhodopsin-like orphan GPCR 0.038 0.0639 0.0639
Loa Loa (eye worm) hypothetical protein 0.0107 0.0099 0.0316
Brugia malayi proprotein convertase 2 0.0548 0.097 0.5315
Onchocerca volvulus 0.0066 0.0018 0.0057
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0193 0.0269 0.0269
Schistosoma mansoni acetylcholine receptor-related 0.0066 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.038 0.0639 0.0639
Brugia malayi Tachykinin-like peptides receptor 99D 0.0853 0.1572 0.8616
Echinococcus granulosus orexin receptor type 2 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0143 0.017 0.0543
Echinococcus granulosus somatostatin receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0069 0.0025 0.0079
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.001 0.0033
Echinococcus granulosus ecdysone induced protein 78C 0.0131 0.0147 0.0183
Schistosoma mansoni biogenic amine receptor 0.038 0.0639 0.0639
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0394 0.0666 0.0826
Schistosoma mansoni biogenic amine receptor 0.038 0.0639 0.0639
Echinococcus multilocularis Tubulin beta 2C chain 0.0067 0.0019 0.0024
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0542 0.0958 0.1187
Echinococcus granulosus neuropeptide receptor A26 0.084 0.1547 0.1918
Loa Loa (eye worm) adenylyl cyclase 3 0.0136 0.0157 0.0501
Echinococcus multilocularis voltage dependent calcium channel 0.0164 0.0212 0.0262
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0531 0.0936 1
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.038 0.0639 0.2035
Brugia malayi map kinase activated protein kinase protein 2 0.0184 0.025 0.1372
Loa Loa (eye worm) PAN domain-containing protein 0.0139 0.0162 0.0516
Schistosoma mansoni biogenic amine (dopamine) receptor 0.038 0.0639 0.0639
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0131 0.0147 0.047
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0118 0.0121 0.0917
Toxoplasma gondii beta-1 tubulin, putative 0.0067 0.0019 0.0047
Loa Loa (eye worm) neuropeptide F receptor 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0077 0.004 0.0128
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0409 0.0696 0.3813
Loa Loa (eye worm) hypothetical protein 0.0108 0.0101 0.0323
Onchocerca volvulus 0.0079 0.0043 0.0137
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0131 0.0147 0.047
Echinococcus granulosus glycoprotein Antigen 5 0.0108 0.0101 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0131 0.0147 0.0147
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0666 0.1204 0.1492
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0143 0.017 0.0211
Echinococcus granulosus rhodopsin orphan GPCR 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0079 0.0043 0.0137
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0066 0.0018 0.0057
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Brugia malayi Cation transporter family protein 0.0143 0.017 0.0934
Schistosoma mansoni hypothetical protein 0.0723 0.1316 0.1316
Echinococcus multilocularis SWI:SNF matrix associated 0.0221 0.0325 0.0402
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0131 0.0147 0.0808
Echinococcus multilocularis ring and YY1 binding protein 0.0079 0.0043 0.0053
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0184 0.025 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.025 0.025
Echinococcus multilocularis G protein coupled receptor 139 0.038 0.0639 0.0792
Schistosoma mansoni peptide (allatostatin)-like receptor 0.1646 0.3139 0.3139
Echinococcus multilocularis glycoprotein Antigen 5 0.0108 0.0101 0.0126
Schistosoma mansoni integrin alpha 0.0297 0.0474 0.0474
Loa Loa (eye worm) hypothetical protein 0.0257 0.0395 0.1258
Brugia malayi SWIB/MDM2 domain containing protein 0.0221 0.0325 0.1779
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0108 0.0101 0.0556
Trypanosoma brucei calpain-like protein, putative 0.0118 0.0121 0.0917
Brugia malayi excitatory GABA receptor EXP-1A 0.0143 0.017 0.0934
Brugia malayi nuclear receptor NHR-88 0.0131 0.0147 0.0808
Loa Loa (eye worm) ACC-1 protein 0.0143 0.017 0.0543
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0118 0.0121 0.1003
Loa Loa (eye worm) hypothetical protein 0.0069 0.0025 0.0079
Echinococcus granulosus biogenic amine 5HT receptor 0.038 0.0639 0.0792
Onchocerca volvulus 0.0139 0.0162 0.0516
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0285 0.045 0.0557
Onchocerca volvulus 0.0139 0.0162 0.0516
Echinococcus granulosus tubulin subunit beta 0.0067 0.0019 0.0024
Schistosoma mansoni hypothetical protein 0.0237 0.0355 0.0355
Toxoplasma gondii microneme protein MIC4 0.0139 0.0162 0.0391
Brugia malayi RE15519p 0.038 0.0639 0.3502
Schistosoma mansoni amine GPCR 0.038 0.0639 0.0639
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Onchocerca volvulus 0.0077 0.004 0.0128
Onchocerca volvulus 0.1646 0.3139 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0131 0.0147 0.047
Onchocerca volvulus 0.0079 0.0043 0.0137
Loa Loa (eye worm) hypothetical protein 0.0193 0.0269 0.0856
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.038 0.0639 0.0639
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0101 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Loa Loa (eye worm) hypothetical protein 0.0108 0.0101 0.0323
Trichomonas vaginalis tubulin epsilon chain, putative 0.0067 0.0019 0.0206
Onchocerca volvulus 0.0058 0.0002 0.0006
Echinococcus multilocularis g-protein coupled receptor 0.038 0.0639 0.0792
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.024 0.0362 0.6471
Echinococcus granulosus integrin alpha 3 0.0227 0.0337 0.0417
Mycobacterium tuberculosis Conserved hypothetical protein 0.0335 0.0549 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0131 0.0147 0.0147
Leishmania major beta tubulin 0.0067 0.0019 0.016
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0131 0.0147 0.0183
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0409 0.0696 1
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) melatonin receptor type 1A 0.038 0.0639 0.2035
Loa Loa (eye worm) trypsin family protein 0.0108 0.0101 0.0323
Schistosoma mansoni biogenic amine receptor 0.038 0.0639 0.0639
Schistosoma mansoni hypothetical protein 0.0237 0.0355 0.0355
Brugia malayi Tubulin beta-1 chain 0.0067 0.0019 0.0106
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0062 0.001 0.0013
Trichomonas vaginalis deoxyribonuclease II, putative 0.0072 0.0031 0.0326
Schistosoma mansoni nuclear hormone receptor 0.0131 0.0147 0.0147
Onchocerca volvulus 0.0131 0.0147 0.047
Echinococcus granulosus adenylate cyclase 9 0.0058 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0077 0.004 0.0128
Schistosoma mansoni tubulin subunit beta 0.0067 0.0019 0.0019
Leishmania major beta tubulin 0.0067 0.0019 0.016
Brugia malayi follicle stimulating hormone receptor 0.038 0.0639 0.3502
Echinococcus multilocularis neuropeptide receptor A26 0.084 0.1547 0.1918
Schistosoma mansoni hypothetical protein 0.038 0.0639 0.0639
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0079 0.0043 0.062
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Schistosoma mansoni amine GPCR 0.038 0.0639 0.0639
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0131 0.0147 0.0183
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0143 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus granulosus glutamate NMDA receptor subunit 0.028 0.0441 0.0546
Loa Loa (eye worm) hypothetical protein 0.0131 0.0147 0.047
Loa Loa (eye worm) PAN domain-containing protein 0.0139 0.0162 0.0516
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0143 0.017 0.0934
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0101 0.0126
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0237 0.0355 0.1948
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0454 0.4855
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0143 0.017 0.1815
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.038 0.0639 0.0792
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.065 0.1171 0.1171
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0118 0.0121 0.0917
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0143 0.017 0.0934
Leishmania major beta tubulin 0.0067 0.0019 0.016
Brugia malayi G protein-coupled receptor 0.038 0.0639 0.3502
Loa Loa (eye worm) hypothetical protein 0.0066 0.0018 0.0057
Brugia malayi hypothetical protein 0.038 0.0639 0.3502
Loa Loa (eye worm) apoptosis regulator protein 0.0394 0.0666 0.2123
Onchocerca volvulus 0.038 0.0639 0.2035
Echinococcus granulosus thyrotropin releasing hormone receptor 0.038 0.0639 0.0792
Toxoplasma gondii beta tubulin 0.0067 0.0019 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0089 0.0956
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0287 0.0454 0.2491
Echinococcus multilocularis SWI:SNF matrix associated 0.0221 0.0325 0.0402
Loa Loa (eye worm) TYRA-2 protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0131 0.0147 0.047
Leishmania major beta tubulin 0.0067 0.0019 0.016
Echinococcus granulosus g protein coupled receptor 0.038 0.0639 0.0792
Echinococcus multilocularis rhodopsin orphan GPCR 0.038 0.0639 0.0792
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0394 0.0666 0.3653
Echinococcus multilocularis nAChR subunit 0.0143 0.017 0.0211
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.024 0.0362 0.1154
Onchocerca volvulus 0.0143 0.017 0.0543
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.2949 0.5711 0.708
Brugia malayi beta-tubulin, identical 0.0067 0.0019 0.0106
Echinococcus multilocularis jun protein 0.0091 0.0067 0.0084
Echinococcus granulosus jun protein 0.0091 0.0067 0.0084
Schistosoma mansoni hypothetical protein 0.0394 0.0666 0.0666
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0531 0.0936 0.116
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0143 0.017 0.0211
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0459 0.0795 0.0795
Schistosoma mansoni hypothetical protein 0.0221 0.0325 0.0325
Schistosoma mansoni rhodopsin-like orphan GPCR 0.038 0.0639 0.0639
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0131 0.0147 0.0183
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0131 0.0147 0.0183
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.038 0.0639 0.0792
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0066 0.0018 0.0022
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0143 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0233 0.0348 0.1108
Onchocerca volvulus 0.038 0.0639 0.2035
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0062 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0131 0.0147 0.047
Brugia malayi Deoxyribonuclease II family protein 0.0072 0.0031 0.0167
Trichomonas vaginalis tubulin, putative 0.0067 0.0019 0.0206
Onchocerca volvulus 0.0108 0.0101 0.0323
Brugia malayi orphan nuclear receptor NR2E1 0.0062 0.001 0.0056
Loa Loa (eye worm) hypothetical protein 0.0131 0.0147 0.047
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0164 0.0212 0.0262
Echinococcus multilocularis rhodopsin orphan GPCR 0.038 0.0639 0.0792
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.038 0.0639 0.0792
Echinococcus multilocularis Tubulin beta 2C chain 0.0067 0.0019 0.0024
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0143 0.017 0.0543
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0058 0.0002 0.0006
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0101 0.0101
Echinococcus granulosus integrin alpha ps 0.0064 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0139 0.0162 0.0516
Schistosoma mansoni nuclear hormone receptor 0.0062 0.001 0.001
Schistosoma mansoni glutamate receptor NMDA 0.028 0.0441 0.0441
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0079 0.0043 0.0236
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0143 0.017 0.0543
Schistosoma mansoni neurotransmitter gated ion channel 0.0077 0.004 0.004
Echinococcus granulosus GPCR family 2 0.0237 0.0355 0.044
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0143 0.017 0.0934
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.001 0.0013
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.028 0.0441 0.0546
Schistosoma mansoni nAChR subunit 0.0143 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.024 0.0362 0.0362
Schistosoma mansoni hypothetical protein 0.0182 0.0248 0.0248
Echinococcus granulosus peptide allatostatin:somatostatin 0.038 0.0639 0.0792
Schistosoma mansoni biogenic amine (dopamine) receptor 0.038 0.0639 0.0639
Schistosoma mansoni thyroid hormone receptor 0.0131 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus granulosus tm gpcr rhodopsin 0.038 0.0639 0.0792
Loa Loa (eye worm) tubulin beta-4 chain 0.0067 0.0019 0.0062
Onchocerca volvulus 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Brugia malayi Trypsin family protein 0.0108 0.0101 0.0556
Brugia malayi PAN domain containing protein 0.0139 0.0162 0.0889
Brugia malayi Nuclear hormone receptor E75 0.0062 0.001 0.0056
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0079 0.0043 0.0236
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus multilocularis g protein coupled receptor 0.038 0.0639 0.0792
Echinococcus multilocularis neuropeptide receptor 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0139 0.0162 0.0516
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0184 0.025 0.031
Brugia malayi Integrin alpha pat-2 precursor 0.0297 0.0474 0.2596
Echinococcus multilocularis nuclear receptor nhr 48 0.0062 0.001 0.0013
Echinococcus multilocularis Tubulin beta 2C chain 0.0067 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0118 0.0121 0.1003
Brugia malayi hypothetical protein 0.0069 0.0025 0.0137
Echinococcus multilocularis FTZ F1 alpha 0.0131 0.0147 0.0183
Echinococcus multilocularis adenylate cyclase type IX 0.0081 0.0048 0.006
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.024 0.0362 0.0362
Schistosoma mansoni deoxyribonuclease II-related 0.0072 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0439 0.0754 0.2403
Echinococcus granulosus SWI:SNF matrix associated 0.0221 0.0325 0.0402
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Loa Loa (eye worm) hypothetical protein 0.0079 0.0043 0.0137
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0164 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.038 0.0639 0.0639
Loa Loa (eye worm) hypothetical protein 0.038 0.0639 0.2035
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0066 0.0018 0.0022
Echinococcus granulosus neuropeptide receptor 0.038 0.0639 0.0792
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0223 0.0327 0.35
Schistosoma mansoni neuropeptide receptor 0.038 0.0639 0.0639
Echinococcus multilocularis deoxyribonuclease ii 0.0072 0.0031 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0517 0.0908 0.2893
Schistosoma mansoni neuropeptide receptor 0.038 0.0639 0.0639
Echinococcus granulosus thyroid hormone receptor alpha 0.0062 0.001 0.0013
Entamoeba histolytica protein kinase, putative 0.0102 0.0089 0.1324
Schistosoma mansoni tubulin subunit beta 0.0067 0.0019 0.0019
Echinococcus granulosus glycine receptor subunit beta 0.0143 0.017 0.0211
Loa Loa (eye worm) hypothetical protein 0.0077 0.004 0.0128
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.2949 0.5711 0.708
Echinococcus granulosus tubulin beta 1 chain 0.0067 0.0019 0.0024
Echinococcus multilocularis tubulin beta 1 chain 0.0067 0.0019 0.0024
Echinococcus multilocularis neuropeptide FF receptor 2 0.0853 0.1572 0.1948
Schistosoma mansoni brg-1 associated factor 0.0221 0.0325 0.0325
Brugia malayi hypothetical protein 0.038 0.0639 0.3502
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0248 0.2649
Echinococcus granulosus voltage dependent calcium channel 0.0164 0.0212 0.0262
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0077 0.004 0.022
Brugia malayi Deoxyribonuclease II family protein 0.0072 0.0031 0.0167
Loa Loa (eye worm) DR-78 0.0062 0.001 0.0033
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0077 0.004 0.022
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.038 0.0639 0.2035
Leishmania major hypothetical protein, conserved 0.0079 0.0043 0.0358
Echinococcus multilocularis neuropeptide Y receptor 0.038 0.0639 0.0792
Giardia lamblia Rab geranylgeranyltransferase 0.0193 0.0269 0.523
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0043 0.062
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0143 0.017 0.0934
Loa Loa (eye worm) hypothetical protein 0.0143 0.017 0.0543
Brugia malayi Transforming growth factor beta like domain containing protein 0.014 0.0165 0.0903
Brugia malayi Dopamine receptor protein 1 0.038 0.0639 0.3502
Leishmania major beta tubulin 0.0067 0.0019 0.016
Loa Loa (eye worm) hypothetical protein 0.0062 0.001 0.0033
Leishmania major hypothetical protein, conserved 0.0079 0.0043 0.0358
Loa Loa (eye worm) hypothetical protein 0.0853 0.1572 0.5007
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.038 0.0639 0.0792
Leishmania major beta tubulin 0.0067 0.0019 0.016
Loa Loa (eye worm) G-protein coupled receptor 0.038 0.0639 0.2035
Echinococcus multilocularis neuropeptide Y receptor 0.038 0.0639 0.0792
Plasmodium vivax hypothetical protein, conserved 0.0221 0.0325 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0101 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0131 0.0147 0.0808
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.001 0.0013
Leishmania major beta tubulin 0.0067 0.0019 0.016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0131 0.0147 0.0808
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0856 0.1578 0.1578
Loa Loa (eye worm) hypothetical protein 0.0164 0.0211 0.0672
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0115 0.0115 0.0633
Echinococcus multilocularis tachykinin peptides receptor 99D 0.038 0.0639 0.0792
Loa Loa (eye worm) hypothetical protein 0.0069 0.0025 0.0079
Loa Loa (eye worm) beta-tubulin 0.0067 0.0019 0.0062
Schistosoma mansoni retinoic acid receptor RXR 0.0131 0.0147 0.0147
Schistosoma mansoni nAChR subunit 0.0143 0.017 0.017
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.038 0.0639 0.0792
Echinococcus granulosus neuropeptide Y receptor 0.038 0.0639 0.0792
Schistosoma mansoni serine-type protease inhibitor 0.512 1 1
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0193 0.0269 0.4705

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 10000 nM Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cells ChEMBL. 11754590
IC50 (binding) > 10000 nM Inhibition of partially purified Geranylgeranyl transferase type I (GGTase-I) from human Burkitt lymphoma (Daudi) cells ChEMBL. 11754590
IC50 (binding) > 10000 nM Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cells ChEMBL. 11754590
IC50 (binding) > 10000 nM Inhibition of partially purified Geranylgeranyl transferase type I (GGTase-I) from human Burkitt lymphoma (Daudi) cells ChEMBL. 11754590

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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