Detailed information for compound 885396

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 326.368 | Formula: C14H18N2O5S
  • H donors: 1 H acceptors: 4 LogP: 0.69 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(cc1)NC(=O)C
  • InChi: 1S/C14H18N2O5S/c1-10(17)15-11-5-7-12(8-6-11)22(19,20)16-9-3-4-13(16)14(18)21-2/h5-8,13H,3-4,9H2,1-2H3,(H,15,17)/t13-/m0/s1
  • InChiKey: GOBJVTLPENTSNS-ZDUSSCGKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Loa Loa (eye worm) neuropeptide F receptor 0.0058 0.0252 0.0254
Echinococcus granulosus importin subunit beta 1 0.0059 0.0257 0.0258
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.028 0.0281
Echinococcus granulosus 7tm_1 domain containing protein 0.0058 0.0252 0.0252
Echinococcus multilocularis GPCR, family 2 0.0062 0.028 0.028
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0092 0.0468 0.0469
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0055
Brugia malayi M-phase phosphoprotein, mpp8 0.0092 0.0468 0.0472
Echinococcus granulosus jumonji domain containing protein 0.0045 0.017 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0149 0.0835 0.3462
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Trypanosoma cruzi cysteine peptidase, putative 0.0366 0.2221 0.3441
Schistosoma mansoni amine GPCR 0.0058 0.0252 0.0338
Brugia malayi Tachykinin-like peptides receptor 99D 0.0512 0.3151 0.3182
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Echinococcus granulosus cathepsin L cysteine proteinase 0.0366 0.2221 0.2226
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0089 0.009
Loa Loa (eye worm) matrixin family protein 0.01 0.0523 0.0528
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0258 0.0346
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Onchocerca volvulus 0.0111 0.0591 0.2661
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0009 0.0037
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Schistosoma mansoni hypothetical protein 0.0524 0.3227 0.4328
Schistosoma mansoni biogenic amine (5HT) receptor 0.0058 0.0252 0.0338
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0092 0.0468 0.1947
Echinococcus granulosus dna polymerase kappa 0.0038 0.0125 0.0126
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Onchocerca volvulus Cathepsin L homolog 0.0111 0.0591 0.2661
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0125 0.0168
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.024 0.0846
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0125 0.029
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.1694 0.7618
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0048 0.0186 0.0801
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Echinococcus multilocularis dro:myosuppressin receptor 0.0058 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0027 0.0057 0.02
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0092 0.0468 0.2073
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0468 0.1917
Echinococcus multilocularis cathepsin L 0.0149 0.0835 0.0835
Echinococcus multilocularis tissue type plasminogen activator 0.0105 0.0549 0.0549
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0092 0.0468 0.0627
Loa Loa (eye worm) hypothetical protein 0.0137 0.0758 0.0766
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0382 0.0513
Trypanosoma brucei cysteine peptidase C (CPC) 0.0395 0.2402 1
Onchocerca volvulus 0.0092 0.0468 0.2105
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.1694 0.7618
Loa Loa (eye worm) melatonin receptor type 1A 0.0058 0.0252 0.0254
Loa Loa (eye worm) fibroinase 0.0366 0.2221 0.2243
Plasmodium vivax vivapain-3 0.0149 0.0835 0.3594
Echinococcus granulosus cathepsin b 0.1028 0.6445 0.6459
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0104 0.0544 0.0837
Echinococcus granulosus neuropeptide receptor A26 0.0569 0.3516 0.3523
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0158 0.0238
Plasmodium vivax serine-repeat antigen (SERA) 0.0111 0.0591 0.2468
Echinococcus multilocularis neuropeptide Y receptor 0.0058 0.0252 0.0252
Onchocerca volvulus Cathepsin L homolog 0.0366 0.2221 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0149 0.0831 0.0831
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0125 0.0187
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0005 0.0005
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0111 0.0591 0.2468
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0057 0.0057
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0057 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0252 0.0338
Echinococcus multilocularis cathepsin L 0.0111 0.0591 0.0591
Giardia lamblia Cathepsin L-like protease 0.0111 0.0591 0.2433
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Trypanosoma cruzi UDP-galactopyranose mutase 0.0028 0.006 0.0086
Loa Loa (eye worm) hypothetical protein 0.0111 0.0591 0.0597
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0591 0.0597
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0111 0.0591 0.2433
Plasmodium vivax hypothetical protein, conserved 0.0028 0.006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0591 0.2433
Echinococcus granulosus glutamate receptor 2 0.0071 0.0335 0.0335
Brugia malayi neuropeptide F receptor 0.0058 0.0252 0.0254
Schistosoma mansoni opsin-like receptor 0.0058 0.0252 0.0338
Loa Loa (eye worm) hypothetical protein 0.0051 0.0206 0.0208
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Schistosoma mansoni hypothetical protein 0.011 0.0582 0.0781
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.024 0.024
Trypanosoma cruzi cysteine proteinase, putative 0.0149 0.0835 0.1288
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0252 0.0338
Brugia malayi beta-lactamase family protein 0.0078 0.0382 0.0386
Schistosoma mansoni cathepsin F (C01 family) 0.0366 0.2221 0.2979
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0125 0.0127
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0366 0.2221 0.2243
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Echinococcus granulosus serotonin receptor 0.0058 0.0252 0.0252
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0037 0.0129
Chlamydia trachomatis protoporphyrinogen oxidase 0.0028 0.006 0.5
Echinococcus granulosus glutamate receptor 4 0.0042 0.0147 0.0148
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0158 0.0623
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0261 0.1547 0.2074
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0094 0.0126
Loa Loa (eye worm) hypothetical protein 0.0032 0.0089 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0591 0.2433
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0133 0.0133
Echinococcus granulosus orexin receptor type 2 0.0058 0.0252 0.0252
Brugia malayi Cathepsin L-like precursor 0.0366 0.2221 0.2243
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1028 0.6445 0.8645
Loa Loa (eye worm) hypothetical protein 0.0028 0.006 0.0061
Onchocerca volvulus 0.0366 0.2221 1
Giardia lamblia Cathepsin B precursor 0.0395 0.2402 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0591 0.0793
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0591 0.2433
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0366 0.2221 0.9245
Trypanosoma cruzi cysteine peptidase, putative 0.0366 0.2221 0.3441
Loa Loa (eye worm) hypothetical protein 0.011 0.0582 0.0588
Onchocerca volvulus 0.011 0.0582 0.2621
Trichomonas vaginalis chromobox protein, putative 0.0156 0.0881 0.3644
Echinococcus granulosus chromobox protein 1 0.0156 0.0881 0.0883
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0005 0.0005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0186 0.0741
Schistosoma mansoni chromobox protein 0.0156 0.0881 0.1182
Echinococcus multilocularis Chromo domain 0.0092 0.0468 0.0468
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0107 0.0107
Plasmodium vivax unspecified product 0.0038 0.0126 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0468 0.1917
Echinococcus multilocularis fmrfamide receptor 0.0058 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0092 0.0468 0.0472
Loa Loa (eye worm) hypothetical protein 0.0149 0.0832 0.0841
Loa Loa (eye worm) hypothetical protein 0.0042 0.0147 0.0149
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0111 0.0591 0.0793
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0158 0.0238
Loa Loa (eye worm) hypothetical protein 0.0092 0.0468 0.0472
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Loa Loa (eye worm) hypothetical protein 0.0111 0.0591 0.0597
Loa Loa (eye worm) prolyl oligopeptidase 0.0027 0.0057 0.0057
Schistosoma mansoni ran 0.0043 0.0158 0.0212
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0057 0.0057
Leishmania major DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Plasmodium vivax unspecified product 0.0111 0.0591 0.2468
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0092 0.0468 0.1917
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0055
Schistosoma mansoni ap endonuclease 0.0056 0.024 0.0322
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0125 0.0503
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0125 0.0125
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0158 0.0658
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0122 0.0664 0.2988
Echinococcus multilocularis prolyl endopeptidase 0.0261 0.1547 0.1547
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0027 0.0057 0.0057
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0027 0.0057 0.0076
Schistosoma mansoni amine GPCR 0.0058 0.0252 0.0338
Trichomonas vaginalis chromobox protein, putative 0.0156 0.0881 0.3644
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0111 0.0591 0.0597
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0009 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0149 0.0835 0.3451
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0092 0.0468 0.0468
Brugia malayi PHD-finger family protein 0.0032 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.0045 0.0171 0.0173
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0125 0.0187
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Trichomonas vaginalis ran, putative 0.0043 0.0158 0.0623
Echinococcus multilocularis geminin 0.0524 0.3227 0.3227
Echinococcus multilocularis neuropeptides capa receptor 0.0058 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0261 0.1547 0.1562
Brugia malayi cathepsin Z-like cysteine proteinase 0.0111 0.0591 0.0597
Brugia malayi hypothetical protein 0.0092 0.0468 0.0472
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0125 0.0127
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0086 0.0086
Brugia malayi jmjC domain containing protein 0.0039 0.0133 0.0134
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0149 0.0835 0.1119
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0058 0.0252 0.0252
Giardia lamblia Cysteine protease 0.0111 0.0591 0.2433
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0057 0.0081
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0058 0.0252 0.0254
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0158 0.0468
Schistosoma mansoni adenoreceptor 0.0058 0.0252 0.0338
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0125 0.0125
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0125 0.0187
Plasmodium falciparum phd finger protein, putative 0.0032 0.0089 0.0363
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0028 0.006 0.0346
Brugia malayi SWIRM domain containing protein 0.0149 0.0832 0.0841
Schistosoma mansoni hypothetical protein 0.0135 0.0742 0.0995
Schistosoma mansoni hypothetical protein 0.0032 0.0089 0.012
Loa Loa (eye worm) heterochromatin protein 1 0.0156 0.0881 0.089
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0133 0.0178
Entamoeba histolytica cysteine protease, putative 0.0366 0.2221 1
Loa Loa (eye worm) glutamate receptor 1 0.0066 0.0305 0.0308
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Echinococcus multilocularis inhibitor of apoptosis protein 0.011 0.0582 0.0582
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.024 0.0667
Schistosoma mansoni hypothetical protein 0.0062 0.028 0.0376
Trypanosoma brucei unspecified product 0.0038 0.0125 0.0503
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0005 0.0005
Onchocerca volvulus 0.0051 0.0206 0.0926
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Brugia malayi Cathepsin L-like precursor 0.0366 0.2221 0.2243
Giardia lamblia Alanyl dipeptidyl peptidase 0.0027 0.0057 0.02
Trypanosoma cruzi cysteine proteinase, putative 0.0149 0.0835 0.1288
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0111 0.0591 0.2468
Brugia malayi Dopamine receptor 0.0058 0.0252 0.0254
Echinococcus granulosus prolyl endopeptidase 0.0261 0.1547 0.155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0094 0.0126
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0058 0.0252 0.0254
Onchocerca volvulus 0.0058 0.0252 0.1134
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0058 0.0252 0.0252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0591 0.2433
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0252 0.0252
Plasmodium vivax vivapain-2 0.0366 0.2221 1
Mycobacterium tuberculosis Conserved protein 0.0078 0.0382 0.1135
Brugia malayi Cathepsin L-like precursor 0.0366 0.2221 0.2243
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Onchocerca volvulus 0.0058 0.0252 0.1134
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0057
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0092 0.0468 0.1917
Brugia malayi Bromodomain containing protein 0.0032 0.0089 0.009
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0092 0.0468 0.2073
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0111 0.0591 0.2433
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0028 0.006 0.0233
Loa Loa (eye worm) hypothetical protein 0.011 0.0582 0.0588
Brugia malayi Cathepsin L-like cysteine proteinase 0.0328 0.1977 0.1997
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.1694 1
Loa Loa (eye worm) RecQ helicase 0.002 0.0009 0.0009
Schistosoma mansoni glutamate receptor kainate 0.0025 0.004 0.0053
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0055 0.0234 0.0237
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0058 0.0252 0.0252
Onchocerca volvulus 0.0058 0.0252 0.1134
Brugia malayi Papain family cysteine protease containing protein 0.0149 0.0835 0.0843
Leishmania major cathepsin L-like protease 0.0366 0.2221 0.9246
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0092 0.0468 0.1917
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.011 0.0582 0.0781
Loa Loa (eye worm) hypothetical protein 0.0105 0.0549 0.0555
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0037 0.0203
Brugia malayi cathepsin B-like cysteine proteinase 0.1028 0.6445 0.6509
Loa Loa (eye worm) CHromoDomain protein family member 0.0092 0.0468 0.0472
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0111 0.0591 0.2632
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Mycobacterium tuberculosis Possible penicillin-binding protein 0.05 0.3076 1
Trypanosoma cruzi cysteine protease, putative 0.0149 0.0835 0.1288
Trichomonas vaginalis set domain proteins, putative 0.0263 0.1563 0.6494
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Plasmodium falciparum cysteine proteinase falcipain 3 0.0366 0.2221 1
Schistosoma mansoni ATP-binding cassette transporter 0.0025 0.004 0.0053
Plasmodium vivax vivapain-2 0.0366 0.2221 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0089 0.0089
Echinococcus granulosus tm gpcr rhodopsin 0.0058 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0092 0.0468 0.0472
Mycobacterium ulcerans dehydrogenase 0.0028 0.006 0.0346
Toxoplasma gondii cathepsin CPL 0.0366 0.2221 0.9248
Brugia malayi G-protein coupled receptor 0.0058 0.0252 0.0254
Echinococcus granulosus peregrin 0.0032 0.0089 0.0089
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Trypanosoma cruzi major cysteine proteinase, putative 0.0111 0.0591 0.091
Brugia malayi Cytochrome P450 family protein 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0059 0.0257 0.026
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0111 0.0591 0.2468
Leishmania major cathepsin L-like protease 0.0366 0.2221 0.9246
Brugia malayi prostaglandin transporter 0.0027 0.0055 0.0055
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0027 0.0057 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.005 0.0189
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.028 0.0281
Echinococcus granulosus biogenic amine 5HT receptor 0.0058 0.0252 0.0252
Onchocerca volvulus Cathepsin L homolog 0.0366 0.2221 1
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0468 0.1917
Schistosoma mansoni neuropeptide F-like receptor 0.0058 0.0252 0.0338
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0106 0.056 0.0561
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0197 0.1139 0.1151
Loa Loa (eye worm) hypothetical protein 0.0045 0.0171 0.0173
Trypanosoma cruzi cysteine peptidase, putative 0.0149 0.0835 0.1288
Loa Loa (eye worm) glutamate receptor 2 0.0025 0.004 0.004
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0111 0.0591 0.0597
Brugia malayi neuropeptide F receptor 0.0058 0.0252 0.0254
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0125 0.0187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1694 0.7043
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Plasmodium vivax hypothetical protein, conserved 0.0078 0.0382 0.1503
Mycobacterium ulcerans hypothetical protein 0.0024 0.0037 0.0203
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0058 0.0252 0.0254
Brugia malayi Papain family cysteine protease containing protein 0.0366 0.2221 0.2243
Entamoeba histolytica hypothetical protein 0.0111 0.0591 0.2632
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.0382 0.0383
Trichomonas vaginalis esterase, putative 0.0078 0.0382 0.156
Brugia malayi cathepsin F-like cysteine proteinase 0.0038 0.0126 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0366 0.2221 0.9245
Trypanosoma cruzi oligopeptidase b 0.0104 0.0544 0.0837
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0104 0.0544 0.0837
Loa Loa (eye worm) hypothetical protein 0.0038 0.0126 0.0127
Leishmania major importin beta-1 subunit, putative 0.0048 0.0186 0.0757
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Echinococcus multilocularis snurportin 1 0.0627 0.3882 0.3882
Loa Loa (eye worm) hypothetical protein 0.0092 0.0468 0.0472
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0149 0.0835 0.3451
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0133 0.0133
Onchocerca volvulus 0.0064 0.0292 0.1315
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0028 0.006 0.0016
Plasmodium vivax importin-beta 2, putative 0.0059 0.0257 0.0925
Trypanosoma cruzi prolyl endopeptidase 0.0261 0.1547 0.2394
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0158 0.0674
Echinococcus granulosus hypothetical protein 0.0058 0.0252 0.0252
Echinococcus multilocularis peregrin 0.0032 0.0089 0.0089
Onchocerca volvulus 0.0125 0.0679 0.3059
Giardia lamblia DINP protein human, muc B family 0.0038 0.0125 0.0487
Onchocerca volvulus 0.0024 0.0037 0.0168
Onchocerca volvulus 0.0366 0.2221 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.0382 0.1135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Plasmodium vivax ataxin-2 like protein, putative 0.0078 0.0383 0.1508
Echinococcus multilocularis cathepsin b 0.1028 0.6445 0.6445
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0383 0.0587
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0258 0.1577
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.0382 0.1135
Schistosoma mansoni chromobox protein 0.0156 0.0881 0.1182
Trypanosoma cruzi cruzipain precursor, putative 0.0038 0.0126 0.0188
Brugia malayi Glutamate receptor 2 precursor 0.0066 0.0305 0.0308
Toxoplasma gondii ABC1 family protein 0.0078 0.0382 0.1591
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0092 0.0468 0.0627
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.0382 0.1135
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0186 0.0282
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0058 0.0252 0.0252
Brugia malayi Serotonin receptor 0.0058 0.0252 0.0254
Giardia lamblia Cysteine protease 0.0111 0.0591 0.2433
Onchocerca volvulus 0.0058 0.0252 0.1134
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0058 0.0252 0.0252
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0261 0.1547 0.6432
Entamoeba histolytica cysteine proteinase, putative 0.0149 0.0835 0.3733
Echinococcus multilocularis neuropeptide Y receptor 0.0058 0.0252 0.0252
Schistosoma mansoni growth hormone secretagogue receptor 0.0058 0.0252 0.0338
Trichomonas vaginalis hypothetical protein 0.0092 0.0468 0.1917
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0092 0.0468 0.0469
Toxoplasma gondii cathepsin CPC1 0.0111 0.0591 0.2461
Loa Loa (eye worm) hypothetical protein 0.0078 0.0383 0.0387
Schistosoma mansoni cathepsin B (C01 family) 0.0111 0.0591 0.0793
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.0382 0.1135
Giardia lamblia Cysteine protease 0.0111 0.0591 0.2433
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0366 0.2221 0.9245
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0382 0.156
Entamoeba histolytica prolyl oligopeptidase family protein 0.0027 0.0057 0.0217
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Entamoeba histolytica cysteine protease, putative 0.0111 0.0591 0.2632
Leishmania major oligopeptidase b 0.0104 0.0544 0.225
Echinococcus granulosus neuropeptide Y receptor 0.0058 0.0252 0.0252
Schistosoma mansoni chromobox protein 0.0092 0.0468 0.0627
Onchocerca volvulus 0.0058 0.0252 0.1134
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0549 0.0846
Echinococcus granulosus Chromobox protein 3 0.0092 0.0468 0.0469
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Echinococcus granulosus G protein coupled receptor 139 0.0058 0.0252 0.0252
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.1359 0.1372
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.0382 0.1135
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0092 0.0468 0.1917
Loa Loa (eye worm) cathepsin B 0.0395 0.2402 0.2425
Entamoeba histolytica cysteine proteinase, putative 0.0366 0.2221 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0111 0.0591 0.0793
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0058 0.0252 0.0254
Loa Loa (eye worm) hypothetical protein 0.0366 0.2221 0.2243
Loa Loa (eye worm) hypothetical protein 0.0328 0.1977 0.1997
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0092 0.0468 0.1917
Brugia malayi AKH receptor 0.0058 0.0252 0.0254
Entamoeba histolytica hypothetical protein 0.0092 0.0468 0.2073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1694 0.7043
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0125 0.0503
Onchocerca volvulus 0.0078 0.0382 0.1721
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0071 0.0335 0.0335
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0252 0.0338
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Echinococcus granulosus dna polymerase eta 0.0038 0.0125 0.0126
Trypanosoma cruzi oligopeptidase b 0.0104 0.0544 0.0837
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0258 0.0346
Onchocerca volvulus 0.0058 0.0252 0.1134
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0165 0.0933 0.0935
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0089 0.0371
Brugia malayi Cathepsin L-like precursor 0.0328 0.1977 0.1997
Onchocerca volvulus Alhambra homolog 0.0032 0.0089 0.0401
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Echinococcus multilocularis glutamate receptor 2 0.0062 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Echinococcus granulosus alpha 1A adrenergic receptor 0.0058 0.0252 0.0252
Brugia malayi jmjC domain containing protein 0.0106 0.056 0.0565
Schistosoma mansoni hypothetical protein 0.0058 0.0252 0.0338
Echinococcus multilocularis fmrfamide receptor 0.0058 0.0252 0.0252
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0058 0.0252 0.0252
Brugia malayi Angiotensin-converting enzyme family protein 0.157 0.9902 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Schistosoma mansoni DNA polymerase eta 0.0038 0.0125 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0111 0.0591 0.2433
Brugia malayi fibroinase precursor 0.0111 0.0591 0.0597
Onchocerca volvulus 0.0027 0.0055 0.0246
Trypanosoma brucei unspecified product 0.0026 0.005 0.0189
Loa Loa (eye worm) hypothetical protein 0.0024 0.0037 0.0038
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0125 0.0487
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0366 0.2221 0.9245
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0386
Giardia lamblia Cathepsin B precursor 0.0395 0.2402 1
Entamoeba histolytica cysteine proteinase, putative 0.0149 0.0835 0.3733
Echinococcus multilocularis cysteine protease 0.0366 0.2221 0.2221
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0104 0.0544 0.225
Echinococcus granulosus cathepsin l cysteine peptidase 0.0366 0.2221 0.2226
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Entamoeba histolytica cysteine protease, putative 0.0111 0.0591 0.2632
Echinococcus granulosus glutamate NMDA receptor subunit 0.0025 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Toxoplasma gondii preprocathepsin c precursor, putative 0.0111 0.0591 0.2461
Giardia lamblia Cathepsin L precursor 0.0111 0.0591 0.2433
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0058 0.0252 0.0252
Echinococcus granulosus inhibitor of apoptosis protein 0.011 0.0582 0.0583
Loa Loa (eye worm) hypothetical protein 0.0045 0.0171 0.0173
Echinococcus multilocularis serotonin receptor 0.0058 0.0252 0.0252
Mycobacterium tuberculosis Conserved protein 0.0078 0.0382 0.1135
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0125 0.0503
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1694 0.7043
Loa Loa (eye worm) hypothetical protein 0.0328 0.1977 0.1997
Echinococcus granulosus chromobox protein 1 0.0156 0.0881 0.0883
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0767 0.4755
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0158 0.0158
Toxoplasma gondii kringle domain-containing protein 0.0105 0.0549 0.2288
Plasmodium vivax heterochromatin protein 1, putative 0.0092 0.0468 0.1898
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.011 0.0582 0.0588
Plasmodium falciparum serine repeat antigen 8 0.0111 0.0591 0.2632
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0058 0.0252 0.0252
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0092 0.0468 0.1947
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0009 0.0037
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0037 0.0136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0252 0.0338
Onchocerca volvulus 0.0366 0.2221 1
Brugia malayi Valyl-tRNA synthetase 0.0092 0.0468 0.0472
Echinococcus granulosus g protein coupled receptor 0.0058 0.0252 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0078 0.0291
Onchocerca volvulus Cathepsin F homolog 0.0366 0.2221 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Schistosoma mansoni hypothetical protein 0.0058 0.0252 0.0338
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0037 0.0129
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0058 0.0252 0.1134
Loa Loa (eye worm) hypothetical protein 0.0042 0.0147 0.0149
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0058 0.0252 0.0252
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Brugia malayi Cytochrome P450 family protein 0.0048 0.0191 0.0193
Brugia malayi cathepsin Z-like cysteine proteinase 0.0111 0.0591 0.0597
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0137 0.0758 0.1017
Loa Loa (eye worm) hypothetical protein 0.0148 0.0827 0.0835
Loa Loa (eye worm) hypothetical protein 0.0034 0.0099 0.01
Brugia malayi amine oxidase, flavin-containing family protein 0.0039 0.0134 0.0136
Brugia malayi SET domain containing protein 0.0093 0.0475 0.048
Giardia lamblia Encystation-specific protease 0.0111 0.0591 0.2433
Mycobacterium ulcerans monoamine oxidase 0.0028 0.006 0.0346
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Trypanosoma brucei prolyl oligopeptidase, putative 0.0104 0.0544 0.225
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0125 0.0752
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0468 0.1917
Trichomonas vaginalis chromobox protein, putative 0.0092 0.0468 0.1917
Mycobacterium ulcerans hydrolase 0.0055 0.0234 0.1431
Schistosoma mansoni neuropeptide receptor 0.0058 0.0252 0.0338
Schistosoma mansoni hypothetical protein 0.0062 0.028 0.0376
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0009 0.0017
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.008 0.0392 0.2415
Onchocerca volvulus 0.0058 0.0252 0.1134
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.024 0.1044
Loa Loa (eye worm) G-protein coupled receptor 0.0058 0.0252 0.0254
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0027 0.0057 0.0217
Onchocerca volvulus 0.0328 0.1977 0.8903
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0149 0.0831 0.0833
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0158 0.0158
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1694 0.7043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Echinococcus granulosus cathepsin b 0.1028 0.6445 0.6459
Loa Loa (eye worm) hypothetical protein 0.0512 0.3151 0.3182
Echinococcus granulosus Chromo domain 0.0092 0.0468 0.0469
Onchocerca volvulus 0.0366 0.2221 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0366 0.2221 0.2221
Schistosoma mansoni alpha-1 adrenergic receptor 0.0058 0.0252 0.0338
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.011 0.0582 0.0582
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0149 0.0831 0.1115
Schistosoma mansoni myosin xvIII 0.0058 0.0252 0.0338
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0133 0.0134
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0767 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0111 0.0591 0.091
Leishmania major cathepsin L-like protease 0.0366 0.2221 0.9246
Giardia lamblia Hypothetical protein 0.0111 0.0591 0.2433
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0158 0.016
Brugia malayi latrophilin 2 splice variant baaae 0.0135 0.0742 0.0749
Echinococcus granulosus neuropeptides capa receptor 0.0058 0.0252 0.0252
Giardia lamblia Cathepsin L precursor 0.0111 0.0591 0.2433
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0383 0.0587
Echinococcus granulosus lysine specific histone demethylase 1A 0.0137 0.0758 0.076
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0382 0.156
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0037 0.0038
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0111 0.0591 0.0597
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.024 0.0965
Trypanosoma cruzi cruzipain precursor, putative 0.0366 0.2221 0.3441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Schistosoma mansoni amine GPCR 0.0058 0.0252 0.0338
Giardia lamblia Cathepsin B precursor 0.0395 0.2402 1
Leishmania major cysteine peptidase A (CPA) 0.0366 0.2221 0.9246
Mycobacterium tuberculosis Possible oxidoreductase 0.0028 0.006 0.0076
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0058 0.0252 0.0338
Loa Loa (eye worm) hypothetical protein 0.0038 0.0125 0.0127
Echinococcus multilocularis muscleblind protein 0.0148 0.0827 0.0827
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0092 0.0468 0.1917
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0058 0.0252 0.0338
Echinococcus multilocularis glutamate receptor 2 0.0066 0.0305 0.0305
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0055 0.0055
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0027 0.0057 0.0237
Brugia malayi cathepsin L-like precursor 0.0328 0.1977 0.1997
Echinococcus granulosus cysteine protease 0.0149 0.0835 0.0836
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0191 0.0193
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Brugia malayi Matrixin family protein 0.0045 0.0171 0.0173
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0009 0.0006
Plasmodium falciparum peptidase, putative 0.0027 0.0057 0.0217
Schistosoma mansoni hypothetical protein 0.0524 0.3227 0.4328
Schistosoma mansoni neuropeptide receptor 0.0058 0.0252 0.0338
Echinococcus multilocularis orexin receptor type 2 0.0058 0.0252 0.0252
Onchocerca volvulus 0.0058 0.0252 0.1134
Brugia malayi ORL1-like opioid receptor 0.0058 0.0252 0.0254
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0591 0.0793
Onchocerca volvulus 0.0078 0.0382 0.1721
Echinococcus granulosus tm gpcr rhodopsin 0.1582 0.9979 1
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0051 0.0206 0.0206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0149 0.0831 0.1115
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0057 0.0217
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.024 0.0242
Echinococcus granulosus muscleblind protein 0.0148 0.0827 0.0828
Onchocerca volvulus 0.0366 0.2221 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0252 0.0338
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Loa Loa (eye worm) hypothetical protein 0.0111 0.0591 0.0597
Schistosoma mansoni organic anion transporter 0.0027 0.0055 0.0073
Plasmodium falciparum serine repeat antigen 7 0.0111 0.0591 0.2632
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Onchocerca volvulus Matrilysin homolog 0.0045 0.0171 0.0771
Entamoeba histolytica hypothetical protein 0.0092 0.0468 0.2073
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0009 0.0009
Brugia malayi hypothetical protein 0.0078 0.0383 0.0387
Schistosoma mansoni glutamate receptor kainate 0.0025 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0328 0.1977 0.1997
Loa Loa (eye worm) hypothetical protein 0.0092 0.0468 0.0472
Schistosoma mansoni memapsin-2 (A01 family) 0.0419 0.2555 0.3427
Echinococcus granulosus neuropeptide receptor 0.0058 0.0252 0.0252
Onchocerca volvulus 0.0058 0.0252 0.1134
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0092 0.0468 0.0627
Schistosoma mansoni DNA helicase recq5 0.002 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Brugia malayi Muscleblind-like protein 0.0148 0.0827 0.0835
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0092 0.0468 0.0472
Leishmania major hypothetical protein, conserved 0.0078 0.0383 0.1578
Echinococcus granulosus glutamate receptor subunit protein glur 0.0051 0.0206 0.0206
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0028 0.006 0.0251
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1694 0.7043
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0206 0.0276
Brugia malayi prolyl oligopeptidase family protein 0.0261 0.1547 0.1562
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0111 0.0591 0.2433
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0252 0.0252
Entamoeba histolytica cysteine proteinase, putative 0.0149 0.0835 0.3733
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0125 0.0127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0092 0.0468 0.1917
Plasmodium falciparum serine repeat antigen 2 0.0111 0.0591 0.2632
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0094 0.0392
Giardia lamblia Cathepsin L precursor 0.0111 0.0591 0.2433
Onchocerca volvulus 0.0058 0.0252 0.1134
Leishmania major cathepsin L-like protease 0.0366 0.2221 0.9246
Giardia lamblia Alanyl dipeptidyl peptidase 0.0027 0.0057 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0468 0.1917
Schistosoma mansoni amine GPCR 0.0058 0.0252 0.0338
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0028 0.006 0.0314
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0027 0.0057 0.0217
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0383 0.1692
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0104 0.0544 0.225
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0257 0.1052
Mycobacterium leprae Probable lipase LipE 0.0078 0.0382 0.4723
Echinococcus granulosus baculoviral IAP repeat containing protein 0.011 0.0582 0.0583
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0258 0.0258
Echinococcus granulosus geminin 0.0524 0.3227 0.3234
Brugia malayi Cathepsin L-like precursor 0.0366 0.2221 0.2243
Giardia lamblia Cathepsin B precursor 0.0111 0.0591 0.2433
Plasmodium falciparum serine repeat antigen 6 0.0111 0.0591 0.2632
Schistosoma mansoni hypothetical protein 0.0062 0.028 0.0376
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Brugia malayi G protein-coupled receptor F59B2.13 0.0058 0.0252 0.0254
Schistosoma mansoni cathepsin S (C01 family) 0.0111 0.0591 0.0793
Onchocerca volvulus 0.0058 0.0252 0.1134
Echinococcus granulosus glutamate receptor 1 0.0042 0.0147 0.0148
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.028 0.0283
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.1694 0.7043
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1028 0.6445 1
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.011 0.0582 0.0588
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0058 0.0252 0.0254
Echinococcus multilocularis acylamino acid releasing enzyme 0.0027 0.0057 0.0057
Echinococcus granulosus cathepsin L 0.0149 0.0835 0.0836
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Entamoeba histolytica cysteine protease, putative 0.0111 0.0591 0.2632
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0165 0.0933 0.0933
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0149 0.0835 0.1119
Loa Loa (eye worm) cysteine protease 0.0366 0.2221 0.2243
Echinococcus multilocularis protoporphyrinogen oxidase 0.0028 0.006 0.006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0125 0.0187
Schistosoma mansoni amine GPCR 0.0058 0.0252 0.0338
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0038 0.0126 0.0127
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0037 0.0203
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0111 0.0591 0.2433
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0092 0.0468 0.1917
Loa Loa (eye worm) hypothetical protein 0.0038 0.0126 0.0127
Entamoeba histolytica cysteine protease, putative 0.0111 0.0591 0.2632
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0591 0.2433
Brugia malayi hypothetical protein 0.0027 0.0055 0.0055
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0058 0.0252 0.0338
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0105 0.0549 0.2276
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0055
Echinococcus multilocularis bloom syndrome protein 0.002 0.0009 0.0009
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0125 0.0503
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0111 0.0591 0.2632
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.024 0.0965
Echinococcus multilocularis cathepsin L cysteine protease 0.0366 0.2221 0.2221
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.024 0.024
Plasmodium falciparum cysteine proteinase falcipain 1 0.0149 0.0835 0.3733
Onchocerca volvulus 0.0058 0.0252 0.1134
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.024 0.0365
Brugia malayi putative neuropeptide receptor 0.0058 0.0252 0.0254
Brugia malayi Matrixin family protein 0.0045 0.0171 0.0173
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0107 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0591 0.2433
Echinococcus granulosus neuropeptide FF receptor 2 0.0512 0.3151 0.3158
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0027 0.0057 0.0217
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Loa Loa (eye worm) hypothetical protein 0.0024 0.0037 0.0038
Echinococcus multilocularis cathepsin L cysteine protease 0.0366 0.2221 0.2221
Echinococcus multilocularis chromobox protein 1 0.0156 0.0881 0.0881
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0058 0.0252 0.0252
Schistosoma mansoni neuropeptide F-like receptor 0.0058 0.0252 0.0338
Onchocerca volvulus 0.0058 0.0252 0.1134
Loa Loa (eye worm) hypothetical protein 0.0111 0.0591 0.0597
Brugia malayi Pre-SET motif family protein 0.0231 0.1359 0.1372
Leishmania major cathepsin L-like protease 0.0366 0.2221 0.9246
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0111 0.0591 0.2468
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0058 0.0252 0.0254
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0058 0.0252 0.0252
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0111 0.0591 0.2468
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Echinococcus granulosus cathepsin l1 0.0366 0.2221 0.2226
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.024 0.5
Schistosoma mansoni cathepsin F (C01 family) 0.0366 0.2221 0.2979
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Mycobacterium leprae PROBABLE HYDROLASE 0.0055 0.0234 0.2698
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0258 0.1073
Toxoplasma gondii cathepsin CPC2 0.0111 0.0591 0.2461
Echinococcus granulosus neuropeptide receptor 0.0058 0.0252 0.0252
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1694 0.7043
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0027 0.0057 0.02
Brugia malayi hypothetical protein 0.0028 0.006 0.0061
Echinococcus granulosus tissue type plasminogen activator 0.0105 0.0549 0.0551
Schistosoma mansoni glutamate receptor NMDA 0.0025 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0055 0.0055
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0149 0.0835 0.1288
Brugia malayi Serotonin receptor 0.0058 0.0252 0.0254
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0037 0.0203
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0057 0.0081
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0382 0.156
Schistosoma mansoni chromobox protein 0.1186 0.7456 1
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0382 0.1574
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0252 0.0338
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0058 0.0252 0.0338
Schistosoma mansoni glutamate receptor kainate 0.0025 0.004 0.0053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0058 0.0252 0.0252
Onchocerca volvulus Deterin homolog 0.011 0.0582 0.2621
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0104 0.0544 0.1668
Echinococcus granulosus snurportin 1 0.0627 0.3882 0.3891
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0233 0.1372 0.4392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Brugia malayi follicle stimulating hormone receptor 0.0058 0.0252 0.0254
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0395 0.2402 1
Loa Loa (eye worm) transcription factor SMAD2 0.0136 0.0751 0.0758
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Schistosoma mansoni cathepsin s 0.0038 0.0126 0.0169
Schistosoma mansoni hypothetical protein 0.0035 0.0107 0.0143
Mycobacterium ulcerans lipase LipD 0.0078 0.0382 0.2353
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0055 0.0055
Echinococcus multilocularis neuropeptide s receptor 0.0569 0.3516 0.3516
Brugia malayi hypothetical protein 0.0027 0.0055 0.0055
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0125 0.0168
Mycobacterium tuberculosis Probable peptidase 0.0104 0.0544 0.1668
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0328 0.1977 0.8227
Giardia lamblia Cathepsin L precursor 0.0111 0.0591 0.2433
Loa Loa (eye worm) hypothetical protein 0.0148 0.0827 0.0835
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0111 0.0591 0.2433
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0328 0.1977 0.8227
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0186 0.0741
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0028 0.006 0.0081
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0094 0.0126
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0055 0.0246
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0027 0.0057 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0664 0.2737
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0038 0.0126 0.0127
Brugia malayi Calcitonin receptor-like protein seb-1 0.0197 0.1139 0.1151
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0092 0.0468 0.2073
Echinococcus granulosus peptide allatostatin:somatostatin 0.0058 0.0252 0.0252
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0058 0.0252 0.0254
Echinococcus granulosus fmrfamide receptor 0.0058 0.0252 0.0252
Toxoplasma gondii LsmAD domain-containing protein 0.0078 0.0383 0.1595
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0106 0.056 0.056
Schistosoma mansoni hypothetical protein 0.0105 0.0549 0.0737
Trichomonas vaginalis Heterochromatin protein, putative 0.0092 0.0468 0.1917
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.017 0.017
Onchocerca volvulus 0.0027 0.0055 0.0246
Loa Loa (eye worm) hypothetical protein 0.0039 0.0134 0.0136
Loa Loa (eye worm) TYRA-2 protein 0.0058 0.0252 0.0254
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0111 0.0591 0.2433
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0009 0.0009
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0591 0.0597
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0125 0.029
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Brugia malayi Dopamine receptor protein 1 0.0058 0.0252 0.0254
Trichomonas vaginalis chromobox protein, putative 0.0126 0.0685 0.2825
Plasmodium vivax hypothetical protein, conserved 0.0092 0.0468 0.1898
Brugia malayi cathepsin F-like cysteine proteinase 0.0111 0.0591 0.0597
Echinococcus multilocularis serotonin receptor 0.0058 0.0252 0.0252
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0382 0.0586
Loa Loa (eye worm) hypothetical protein 0.0033 0.0094 0.0095
Onchocerca volvulus Neuropeptide F receptor homolog 0.0058 0.0252 0.1134
Brugia malayi Importin beta-1 subunit 0.0059 0.0257 0.026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.024 0.0365
Loa Loa (eye worm) hypothetical protein 0.0024 0.0037 0.0038
Echinococcus granulosus tachykinin peptides receptor 99D 0.0058 0.0252 0.0252
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0037 0.0203
Loa Loa (eye worm) hypothetical protein 0.0092 0.0468 0.0472
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0111 0.0591 0.2468
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0055 0.0055
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0028 0.006 0.0233
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0111 0.0591 0.2433
Echinococcus multilocularis G-protein coupled receptor, putative 0.0058 0.0252 0.0252
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0094 0.0094
Schistosoma mansoni importin beta-1 0.0059 0.0257 0.0345
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0037 0.0129
Echinococcus granulosus biogenic amine 5HT receptor 0.0058 0.0252 0.0252
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0058 0.0252 0.0252
Giardia lamblia Cathepsin L precursor 0.0111 0.0591 0.2433
Brugia malayi G-protein coupled receptor 0.0058 0.0252 0.0254
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.157 0.9902 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0037 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0037 0.0203
Echinococcus multilocularis glutamate receptor 2 0.0071 0.0335 0.0335
Brugia malayi CHD4 protein 0.0092 0.0468 0.0472
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0125 0.0487
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0009 0.0009
Echinococcus multilocularis glutamate receptor 4 0.0042 0.0147 0.0147
Mycobacterium tuberculosis Probable oxidoreductase 0.027 0.1608 0.5171
Schistosoma mansoni biogenic amine receptor 0.0058 0.0252 0.0338
Giardia lamblia Cathepsin B precursor 0.0111 0.0591 0.2433
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Leishmania major cathepsin L-like protease 0.0366 0.2221 0.9246
Brugia malayi Associated with TFs and helicases family protein 0.0092 0.0468 0.0472
Onchocerca volvulus 0.0058 0.0252 0.1134
Loa Loa (eye worm) neuropeptide F receptor 0.0058 0.0252 0.0254
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0468 0.1917
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0252 0.0338
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.0382 0.0386
Loa Loa (eye worm) hypothetical protein 0.0092 0.0468 0.0472
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0468 0.1917
Onchocerca volvulus 0.0058 0.0252 0.1134
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0395 0.2402 0.3221
Onchocerca volvulus 0.0034 0.0099 0.0448
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0366 0.2221 0.9245
Schistosoma mansoni organic anion transporter 0.0027 0.0055 0.0073
Plasmodium vivax hypothetical protein, conserved 0.0028 0.006 0.0016
Loa Loa (eye worm) matrixin family protein 0.0109 0.0581 0.0587
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0366 0.2221 0.2243
Plasmodium falciparum serine repeat antigen 5 0.0111 0.0591 0.2632
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0386
Brugia malayi Cathepsin L-like precursor 0.0366 0.2221 0.2243
Giardia lamblia Cathepsin B precursor 0.0111 0.0591 0.2433
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.005 0.0189
Brugia malayi Cytochrome P450 family protein 0.0019 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0252 0.0338
Brugia malayi Cathepsin L-like precursor 0.0366 0.2221 0.2243
Loa Loa (eye worm) matrix metalloproteinase 0.0045 0.0171 0.0173
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0252 0.0338
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0037 0.0203
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0037 0.0136
Echinococcus granulosus g protein coupled receptor 0.0058 0.0252 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Leishmania major hypothetical protein, conserved 0.0078 0.0382 0.1574
Toxoplasma gondii cathepsin B 0.0395 0.2402 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0092 0.0468 0.1947
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0027 0.0057 0.0081
Brugia malayi Heterochromatin protein 1 0.0156 0.0881 0.089
Brugia malayi Cathepsin L-like precursor 0.0328 0.1977 0.1997
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0027 0.0057 0.0081
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.024 0.0981
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0111 0.0591 0.2433
Brugia malayi Kringle domain containing protein 0.0105 0.0549 0.0555
Onchocerca volvulus 0.0092 0.0468 0.2105
Mycobacterium tuberculosis Conserved protein 0.0078 0.0382 0.1135
Echinococcus multilocularis 0.0028 0.006 0.006
Leishmania major UDP-galactopyranose mutase 0.0028 0.006 0.0232
Loa Loa (eye worm) hypothetical protein 0.0055 0.0234 0.0237
Plasmodium vivax hypothetical protein, conserved 0.0092 0.0468 0.1898
Loa Loa (eye worm) hypothetical protein 0.0062 0.028 0.0283
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.005 0.0189
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0257 0.107
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0071 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0055
Onchocerca volvulus 0.0027 0.0055 0.0246
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.024 0.1044
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0027 0.0057 0.0237
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0104 0.0544 0.3363
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0058 0.0252 0.0254
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0058 0.0252 0.0254
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1694 0.7043
Trichomonas vaginalis chromobox protein, putative 0.0126 0.0685 0.2825
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Brugia malayi chromobox protein homolog 3 0.0122 0.0664 0.067
Loa Loa (eye worm) beta-lactamase 0.0078 0.0382 0.0386
Echinococcus granulosus acylamino acid releasing enzyme 0.0027 0.0057 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Onchocerca volvulus 0.0366 0.2221 1
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0468 0.1917
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0089 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0591 0.2433
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0366 0.2221 0.2221
Loa Loa (eye worm) hypothetical protein 0.1028 0.6445 0.6509
Echinococcus granulosus somatostatin receptor 0.0058 0.0252 0.0252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0366 0.2221 0.9245
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0027 0.0057 0.0217
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0092 0.0468 0.1917
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0767 0.2402
Plasmodium falciparum cysteine repeat modular protein 1 0.0105 0.0549 0.2443
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0366 0.2221 1
Schistosoma mansoni amine oxidase 0.0028 0.006 0.0081
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0149 0.0831 0.084
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1028 0.6445 0.8645
Entamoeba histolytica cysteine proteinase, putative 0.0366 0.2221 1
Brugia malayi Melatonin receptor type 1A 0.0058 0.0252 0.0254
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Echinococcus granulosus Dipeptidyl peptidase 9 0.0027 0.0057 0.0057
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0125 0.0752
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0149 0.0831 0.0833
Trypanosoma cruzi cysteine peptidase, putative 0.0366 0.2221 0.3441
Echinococcus multilocularis allatostatin A receptor 0.0058 0.0252 0.0252
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0037 0.0203
Schistosoma mansoni neuropeptide receptor 0.0058 0.0252 0.0338
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0058 0.0252 0.0252
Onchocerca volvulus Matrilysin homolog 0.01 0.0523 0.2356
Schistosoma mansoni hypothetical protein 0.0058 0.0252 0.0338
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0069 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0111 0.0591 0.2433
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Echinococcus multilocularis cathepsin b 0.1028 0.6445 0.6445
Brugia malayi Matrixin family protein 0.0045 0.0171 0.0173
Echinococcus multilocularis tumor protein p63 0.0346 0.2092 0.2092
Echinococcus granulosus neuropeptides capa receptor 0.0058 0.0252 0.0252
Trypanosoma brucei PAB1-binding protein , putative 0.0078 0.0383 0.1578
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0058 0.0252 0.0338
Trypanosoma cruzi cysteine peptidase, putative 0.0366 0.2221 0.3441
Schistosoma mansoni ran 0.0043 0.0158 0.0212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0366 0.2221 0.9245
Plasmodium vivax vivapain-1 0.0149 0.0835 0.3594
Brugia malayi RE15519p 0.0058 0.0252 0.0254
Onchocerca volvulus 0.0027 0.0055 0.0246
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.024 0.0965
Brugia malayi Protein cec-1. 0.0092 0.0468 0.0472
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0027 0.0057 0.0076
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0386
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0111 0.0591 0.0793
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Schistosoma mansoni hypothetical protein 0.0062 0.028 0.0376
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0028 0.006 0.0016
Echinococcus granulosus 7TM GPCR rhodopsin 0.0058 0.0252 0.0252
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0092 0.0468 0.0468
Echinococcus granulosus sex peptide receptor 0.0058 0.0252 0.0252
Loa Loa (eye worm) helicase 0.0092 0.0468 0.0472
Entamoeba histolytica cysteine proteinase, putative 0.0328 0.1977 0.8899
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Echinococcus multilocularis g-protein coupled receptor 0.0058 0.0252 0.0252
Mycobacterium tuberculosis Conserved hypothetical protein 0.0028 0.006 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0366 0.2221 0.9245
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0591 0.0597
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0111 0.0591 0.2632
Schistosoma mansoni jumonji domain containing protein 0.0084 0.042 0.0564
Entamoeba histolytica cysteine proteinase 1, putative 0.0149 0.0835 0.3733
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1028 0.6445 0.8645
Trichomonas vaginalis chromobox protein, putative 0.0092 0.0468 0.1917
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0058 0.0252 0.0252
Echinococcus multilocularis G protein coupled receptor 139 0.0058 0.0252 0.0252
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0111 0.0591 0.2468
Brugia malayi Latrophilin receptor protein 2 0.0062 0.028 0.0283
Onchocerca volvulus 0.0027 0.0055 0.0246
Brugia malayi sulfakinin receptor protein 0.0058 0.0252 0.0254
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0028 0.006 0.0346
Brugia malayi RNA, U transporter 1 0.0167 0.0948 0.0957
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0009 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0037 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1694 0.7043
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0158 0.0639
Echinococcus multilocularis muscleblind protein 1 0.0148 0.0827 0.0827
Mycobacterium ulcerans hypothetical protein 0.0078 0.0382 0.2353
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0111 0.0591 0.0793
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0057 0.02
Schistosoma mansoni neuropeptide receptor 0.0058 0.0252 0.0338
Plasmodium vivax SET domain protein, putative 0.0033 0.0094 0.0172
Schistosoma mansoni glutamate receptor NMDA 0.0029 0.0069 0.0093
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.0382 0.0386
Brugia malayi Pre-SET motif family protein 0.0033 0.0094 0.0095
Schistosoma mansoni neuropeptide f receptor 76f 0.0058 0.0252 0.0338
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0058 0.0252 0.0252
Schistosoma mansoni hypothetical protein 0.0058 0.0252 0.0338
Loa Loa (eye worm) prolyl oligopeptidase 0.0027 0.0057 0.0057
Giardia lamblia Cathepsin B precursor 0.0111 0.0591 0.2433
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.0382 0.1135
Brugia malayi Glutamate receptor 1 precursor 0.0066 0.0305 0.0308
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0158 0.016
Loa Loa (eye worm) hypothetical protein 0.0111 0.0591 0.0597
Mycobacterium ulcerans beta-lactamase 0.0078 0.0382 0.2353
Giardia lamblia Cathepsin L precursor 0.0111 0.0591 0.2433
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0027 0.0057 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0664 0.2737
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Brugia malayi Cathepsin L-like precursor 0.0038 0.0126 0.0127
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0089 0.0089
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0092 0.0468 0.2073
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0027 0.0057 0.0217
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0258 0.1577
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Brugia malayi cathepsin L precursor 0.0111 0.0591 0.0597
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0092 0.0468 0.1917
Toxoplasma gondii histone lysine-specific demethylase 0.0028 0.006 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0092 0.0468 0.1917
Loa Loa (eye worm) MH2 domain-containing protein 0.0136 0.0751 0.0758
Schistosoma mansoni DNA helicase recq1 0.002 0.0009 0.0012
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.024 0.0981
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0104 0.0544 0.6942
Plasmodium falciparum serine repeat antigen 1 0.0111 0.0591 0.2632
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0366 0.2221 0.9245
Schistosoma mansoni biogenic amine receptor 0.0058 0.0252 0.0338
Echinococcus granulosus dro:myosuppressin receptor 0.0058 0.0252 0.0252
Giardia lamblia Hypothetical protein 0.0111 0.0591 0.2433
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0027 0.0057 0.0076
Giardia lamblia Cathepsin B precursor 0.0111 0.0591 0.2433
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Plasmodium falciparum importin beta, putative 0.0059 0.0257 0.1122
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0382 0.0586
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0125 0.0679 0.0911
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0069 0.0069
Onchocerca volvulus 0.0105 0.0549 0.2474
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Brugia malayi hypothetical protein 0.0058 0.0252 0.0254
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0089 0.0371
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0386
Plasmodium falciparum protoporphyrinogen oxidase 0.0028 0.006 0.0233
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0027 0.0057 0.0217
Entamoeba histolytica prolyl oligopeptidase family protein 0.0027 0.0057 0.0217
Echinococcus multilocularis neuropeptide receptor A26 0.0569 0.3516 0.3516
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0395 0.2402 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0258 0.0725
Echinococcus multilocularis neuropeptides capa receptor 0.0058 0.0252 0.0252
Echinococcus granulosus g-protein coupled receptor 0.0058 0.0252 0.0252
Mycobacterium ulcerans oxidoreductase 0.0028 0.006 0.0346
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0137 0.0758 0.0758
Loa Loa (eye worm) hypothetical protein 0.0056 0.0237 0.0239
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1028 0.6445 0.8645
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0149 0.0835 0.1119
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0009 0.0009
Onchocerca volvulus 0.0045 0.0171 0.0771
Plasmodium vivax serine-repeat antigen (SERA) 0.0111 0.0591 0.2468
Echinococcus granulosus neuropeptide s receptor 0.0569 0.3516 0.3523
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0383 0.1692
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0591 0.2433
Echinococcus granulosus tumor protein p63 0.0346 0.2092 0.2097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0591 0.2433
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0058 0.0252 0.0338
Leishmania major cathepsin L-like protease 0.0366 0.2221 0.9246
Schistosoma mansoni opsin-like receptor 0.0058 0.0252 0.0338
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0386
Echinococcus multilocularis dna polymerase eta 0.0038 0.0125 0.0125
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.0382 0.0382
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0111 0.0591 0.2433
Brugia malayi beta-lactamase 0.0078 0.0382 0.0386
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0111 0.0591 0.2468
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0055 0.0055
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0028 0.006 0.0346
Onchocerca volvulus 0.0263 0.1563 0.7037
Schistosoma mansoni glutamate receptor AMPA 0.0025 0.004 0.0053
Onchocerca volvulus 0.0058 0.0252 0.1134
Echinococcus multilocularis Chromobox protein 3 0.0092 0.0468 0.0468
Onchocerca volvulus Prolyl endopeptidase homolog 0.0261 0.1547 0.6963
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0058 0.0252 0.0252
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0111 0.0591 0.2468
Plasmodium falciparum heterochromatin protein 1 0.0092 0.0468 0.2073
Echinococcus granulosus cathepsin L cysteine protease 0.0149 0.0835 0.0836
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0058 0.0252 0.0338
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0382 0.0513
Giardia lamblia PHD finger protein 15 0.0032 0.0089 0.0335
Echinococcus multilocularis sex peptide receptor 0.0058 0.0252 0.0252
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0257 0.0257
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0058 0.0252 0.0338
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0366 0.2221 0.9245
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0055 0.0055
Entamoeba histolytica Ran family GTPase 0.0043 0.0158 0.0674
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0092 0.0468 0.0627
Loa Loa (eye worm) hypothetical protein 0.0135 0.0742 0.0749
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0125 0.0126
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0366 0.2221 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Plasmodium falciparum serine repeat antigen 3 0.0111 0.0591 0.2632
Leishmania major DNA polymerase eta, putative 0.0038 0.0125 0.0503
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0111 0.0591 0.0597
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0149 0.0831 0.0831
Echinococcus granulosus tm gpcr rhodopsin 0.0058 0.0252 0.0252
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0057 0.0057
Brugia malayi putative neuropeptide receptor NPR1 0.0058 0.0252 0.0254
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0149 0.0835 0.3462
Trypanosoma cruzi UDP-galactopyranose mutase 0.0028 0.006 0.0086
Echinococcus multilocularis chromobox protein 1 0.0156 0.0881 0.0881
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Schistosoma mansoni biogenic amine (5HT) receptor 0.0058 0.0252 0.0338
Schistosoma mansoni inhibitor of apoptosis protein 0.011 0.0582 0.0781
Echinococcus multilocularis neuropeptide FF receptor 2 0.0512 0.3151 0.3151
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0055 0.0246
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.028 0.028
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0309 0.0312
Schistosoma mansoni histamine h1 receptor 0.0058 0.0252 0.0338
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0089 0.012
Entamoeba histolytica cysteine protease, putative 0.0111 0.0591 0.2632
Brugia malayi Matrixin family protein 0.0109 0.0581 0.0587
Toxoplasma gondii exonuclease III APE 0.0056 0.024 0.0999
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0382 0.156
Entamoeba histolytica cysteine protease, putative 0.0111 0.0591 0.2632
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0591 0.0793
Brugia malayi Protein kinase domain containing protein 0.0105 0.0549 0.0555
Echinococcus granulosus lysine specific histone demethylase 1A 0.0028 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0028 0.006 0.0061
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0257 0.1052
Loa Loa (eye worm) hypothetical protein 0.0137 0.0758 0.0766
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0386
Brugia malayi Dopamine receptor protein 2 0.0058 0.0252 0.0254
Plasmodium vivax unspecified product 0.0149 0.0835 0.3594
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0055 0.0055
Schistosoma mansoni ap endonuclease 0.0056 0.024 0.0322
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.024 0.1466
Brugia malayi Hemopexin family protein 0.0064 0.0292 0.0295
Trypanosoma brucei oligopeptidase b 0.0104 0.0544 0.225
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0078 0.0291
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0092 0.0468 0.1917
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Trypanosoma cruzi cysteine peptidase, putative 0.0038 0.0126 0.0188
Brugia malayi G protein-coupled receptor 0.0058 0.0252 0.0254
Giardia lamblia Cysteine protease 0.0111 0.0591 0.2433
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0069 0.0069
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0468 0.1917
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0094 0.0094
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0133 0.0178
Brugia malayi beta-lactamase family protein 0.0078 0.0382 0.0386
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0149 0.0831 0.1115
Loa Loa (eye worm) ctsf protein 0.0366 0.2221 0.2243
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Schistosoma mansoni hypothetical protein 0.0092 0.0468 0.0627
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0258 0.1055
Schistosoma mansoni opsin-like receptor 0.0058 0.0252 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Loa Loa (eye worm) hypothetical protein 0.0197 0.1139 0.1151
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0395 0.2402 0.3721
Echinococcus multilocularis cysteine protease 0.0366 0.2221 0.2221
Brugia malayi larval opioid receptor 0.0058 0.0252 0.0254
Loa Loa (eye worm) G-protein coupled receptor 0.0058 0.0252 0.0254
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0125 0.0503
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0252 0.0338
Schistosoma mansoni hypothetical protein 0.0627 0.3882 0.5207
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.0382 0.2353
Toxoplasma gondii hypothetical protein 0.0027 0.0057 0.0237
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0111 0.0591 0.2632
Entamoeba histolytica hypothetical protein 0.0092 0.0468 0.2073
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0069 0.007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0186 0.0741
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0058 0.0252 0.0252
Trypanosoma brucei prolyl endopeptidase 0.0261 0.1547 0.6432
Brugia malayi GnHR receptor homolog 0.0058 0.0252 0.0254
Leishmania major hypothetical protein, conserved 0.0105 0.0549 0.2272
Echinococcus granulosus bloom syndrome protein 0.002 0.0009 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0149 0.0835 0.3733
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0382 0.4723
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1582 0.9979 0.9979
Plasmodium falciparum serine repeat antigen 4 0.0111 0.0591 0.2632
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0092 0.0468 0.1917
Schistosoma mansoni hypothetical protein 0.0064 0.0292 0.0392
Loa Loa (eye worm) hypothetical protein 0.0038 0.0126 0.0127
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0069 0.007
Echinococcus granulosus cathepsin L 0.0111 0.0591 0.0592
Schistosoma mansoni cathepsin F (C01 family) 0.0328 0.1977 0.2652
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0055 0.0228
Onchocerca volvulus 0.0058 0.0252 0.1134
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0092 0.0468 0.2073
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0058 0.0252 0.0254
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0149 0.0831 0.084
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0252 0.0338
Schistosoma mansoni biogenic amine receptor 0.0058 0.0252 0.0338
Trichomonas vaginalis chromobox protein, putative 0.0092 0.0468 0.1917
Trypanosoma brucei unspecified product 0.0026 0.005 0.0189
Brugia malayi MH2 domain containing protein 0.0136 0.0751 0.0758
Schistosoma mansoni amine oxidase 0.0028 0.006 0.0081
Echinococcus granulosus g protein coupled receptor 0.0058 0.0252 0.0252
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0069 0.0069
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0094 0.0094
Brugia malayi Matrixin family protein 0.0045 0.0171 0.0173
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0111 0.0591 0.2632
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0382 0.156
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0055 0.0246
Echinococcus granulosus allatostatin A receptor 0.0058 0.0252 0.0252
Toxoplasma gondii prolyl endopeptidase 0.0261 0.1547 0.6439
Brugia malayi hypothetical protein 0.0051 0.0206 0.0208
Loa Loa (eye worm) hypothetical protein 0.0122 0.0664 0.067
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0627 0.3882 0.3921
Echinococcus multilocularis somatostatin receptor 0.0058 0.0252 0.0252
Echinococcus multilocularis neuropeptide receptor 0.0058 0.0252 0.0252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0366 0.2221 0.9245
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0055 0.0078
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0045 0.0171 0.023
Brugia malayi Papain family cysteine protease containing protein 0.0149 0.0835 0.0843
Loa Loa (eye worm) TK/ROR protein kinase 0.0105 0.0549 0.0555
Entamoeba histolytica prolyl oligopeptidase family protein 0.0027 0.0057 0.0217
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0126 0.0685 0.3083
Loa Loa (eye worm) hypothetical protein 0.0042 0.0147 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.028 0.0283
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0125 0.0503
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0125 0.0527
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Giardia lamblia Cathepsin L-like protease 0.0111 0.0591 0.2433
Onchocerca volvulus 0.0149 0.0832 0.3748
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Onchocerca volvulus Matrix metalloproteinase homolog 0.01 0.0523 0.2356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0591 0.2433
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0366 0.2221 0.9246
Leishmania major GTP-binding protein, putative 0.0043 0.0158 0.0639
Echinococcus multilocularis neuropeptide receptor 0.0058 0.0252 0.0252
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0025 0.004 0.004
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0058 0.0252 0.0338
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0058 0.0252 0.0338
Entamoeba histolytica cysteine protease, putative 0.0149 0.0835 0.3733
Loa Loa (eye worm) hypothetical protein 0.0111 0.0591 0.0597
Schistosoma mansoni cathepsin C 0.0111 0.0591 0.0793
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0252 0.0252
Echinococcus granulosus cathepsin l1 0.0328 0.1977 0.1982
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0111 0.0591 0.2433
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0258 0.0258
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0111 0.0591 0.2468
Echinococcus granulosus glutamate receptor 2 0.0062 0.0276 0.0277
Echinococcus granulosus chromobox protein 2 0.1186 0.7456 0.7471
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0037 0.0136
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0328 0.1977 0.3063
Leishmania major cathepsin L-like protease 0.0366 0.2221 0.9246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0591 0.2433
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0366 0.2221 0.9245
Plasmodium falciparum serine repeat antigen 9 0.0111 0.0591 0.2632
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0258 0.1577
Echinococcus granulosus GPCR family 2 0.0062 0.028 0.0281
Entamoeba histolytica cysteine proteinase 2 0.0149 0.0835 0.3733
Echinococcus multilocularis chromobox protein 2 0.1186 0.7456 0.7456
Loa Loa (eye worm) hypothetical protein 0.0058 0.0252 0.0254
Onchocerca volvulus 0.0366 0.2221 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0591 0.0793
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0027 0.0057 0.0256
Brugia malayi cathepsin L-like cysteine proteinase 0.0111 0.0591 0.0597
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0055 0.0234 0.0648
Echinococcus granulosus neuropeptide Y receptor 0.0058 0.0252 0.0252
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.0382 0.1135
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0058 0.0252 0.0252
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.024 0.0242
Onchocerca volvulus 0.0078 0.0382 0.1721
Mycobacterium ulcerans short chain dehydrogenase 0.027 0.1608 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0197 0.1139 0.1151
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0591 0.0793
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0261 0.1547 0.2074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0252 0.0338
Schistosoma mansoni glutamate receptor AMPA 0.0025 0.004 0.0053
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.028 0.028

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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