Detailed information for compound 932453

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 219.367 | Formula: C9H17NOS2
  • H donors: 1 H acceptors: 1 LogP: 3.74 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC[S@+](CCCCN=C=S)[O-]
  • InChi: 1S/C9H17NOS2/c1-2-3-7-13(11)8-5-4-6-10-9-12/h2-8H2,1H3/t13-/m1/s1
  • InChiKey: WJYGVJJHEVMGBN-CYBMUJFWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0075 0.0082 0.0193
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0083 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis tyrosine protein kinase Srms 0.2385 0.4254 0.4254
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0492 0.0836 0.0836
Echinococcus granulosus suppressor of cytokine signaling 6 0.1428 0.2527 0.2527
Mycobacterium tuberculosis Conserved hypothetical protein 0.0141 0.0202 0.2029
Onchocerca volvulus 0.2385 0.4254 1
Schistosoma mansoni tyrosine-protein kinase zap-70 0.1428 0.2527 0.2527
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni hypothetical protein 0.0141 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0141 0.0202 0.0202
Echinococcus granulosus c src tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus granulosus sex peptide receptor 0.0075 0.0082 0.0082
Schistosoma mansoni ephrin receptor 0.0956 0.1674 0.1674
Brugia malayi STAT protein, DNA binding domain containing protein 0.1428 0.2527 0.3958
Echinococcus multilocularis G protein coupled receptor 139 0.0075 0.0082 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0049 0.0034 0.0031
Echinococcus granulosus orexin receptor type 2 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Onchocerca volvulus 0.2385 0.4254 1
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Toxoplasma gondii HEAT repeat-containing protein 0.003 0 0.0003
Loa Loa (eye worm) SH2 domain-containing protein 0.1428 0.2527 0.2853
Onchocerca volvulus 0.0075 0.0082 0.0193
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Onchocerca volvulus 0.0956 0.1674 0.3935
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0083 0.0097 0.0109
Schistosoma mansoni biogenic amine receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Onchocerca volvulus 0.0956 0.1674 0.3935
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0075 0.0082 0.0082
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis receptor type guanylyl cyclase 0.0956 0.1674 0.1674
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0956 0.1674 0.1674
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0084 0.0098 0.0948
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0017 0.0027
Plasmodium vivax protein kinase, putative 0.0956 0.1674 1
Schistosoma mansoni GTPase activating protein 0.1428 0.2527 0.2527
Brugia malayi follicle stimulating hormone receptor 0.0075 0.0082 0.0129
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0043 0.0024 0.0141
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0053 0.006
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0075 0.0082 0.0129
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0083 0.0097 0.0097
Brugia malayi hypothetical protein 0.0044 0.0026 0.004
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) hypothetical protein 0.1369 0.2419 0.2731
Leishmania major hypothetical protein, unknown function 0.0141 0.0202 0.1204
Mycobacterium ulcerans carboxylesterase, LipT 0.0084 0.0098 0.0814
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi AKH receptor 0.0075 0.0082 0.0129
Onchocerca volvulus 0.0956 0.1674 0.3935
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni opsin-like receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Schistosoma mansoni opsin-like receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus tyrosine protein kinase shark 0.2385 0.4254 0.4254
Loa Loa (eye worm) phosphatidylinositol 3 0.0141 0.0202 0.0228
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0153 0.0223 0.0252
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.2195 0.3911 0.3911
Echinococcus multilocularis tyrosine protein kinase Abl 0.2385 0.4254 0.4254
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Echinococcus granulosus raf serine:threonine protein kinase 0.0956 0.1674 0.1674
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus multilocularis dnaJ subfamily B 0.0415 0.0696 0.0696
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0017 0.0017
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0153 0.0223 0.035
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.0294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Onchocerca volvulus 0.1428 0.2527 0.5939
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Echinococcus granulosus SH2 domain containing adapter protein F 0.1428 0.2527 0.2527
Trypanosoma cruzi protein kinase, putative 0.0956 0.1674 0.2606
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni tensin 0.1428 0.2527 0.2527
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0178 0.0268 0.1241
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0067 0.0067
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0178 0.0268 0.0268
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Onchocerca volvulus 0.1428 0.2527 0.5939
Trichomonas vaginalis PIKK family atypical protein kinase 0.0249 0.0396 0.0599
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.0294
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0059 0.0059
Brugia malayi hypothetical protein 0.0039 0.0017 0.0027
Schistosoma mansoni tyrosine kinase 0.1107 0.1946 0.1946
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1225 0.2158 0.3366
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi Carboxylesterase family protein 0.0084 0.0098 0.0153
Loa Loa (eye worm) TK/ABL protein kinase 0.2385 0.4254 0.4804
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0141 0.0202 0.0202
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Entamoeba histolytica tyrosin kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0141 0.0202 0.0294
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0158 0.0232 0.0345
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Echinococcus granulosus tyrosine protein kinase pr2 0.0956 0.1674 0.1674
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0318 0.0478
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1225 0.2158 0.2158
Loa Loa (eye worm) phosphatidylinositol 3 0.0141 0.0202 0.0228
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0014 0.0003
Onchocerca volvulus Tyrosine kinase homolog 0.0956 0.1674 0.3935
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Entamoeba histolytica hypothetical protein 0.0141 0.0202 0.0297
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.064 0.1103 0.1709
Echinococcus granulosus tyrosine protein kinase ABL1 0.2385 0.4254 0.4254
Brugia malayi nuclear hormone receptor 0.0083 0.0097 0.0151
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1428 0.2527 0.2527
Echinococcus multilocularis tyrosine kinase 0.2385 0.4254 0.4254
Loa Loa (eye worm) TK/DDR protein kinase 0.0956 0.1674 0.189
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.064 0.1103 0.1728
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1225 0.2158 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0026 0.0026
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis neuropeptide receptor A26 0.0075 0.0082 0.0082
Entamoeba histolytica ankyrin repeat protein 0.0956 0.1674 0.2608
Onchocerca volvulus 0.2385 0.4254 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0956 0.1674 0.1674
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0082 0.0082
Echinococcus granulosus signal transduction protein lnk realted 0.1428 0.2527 0.2527
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1428 0.2527 0.2527
Echinococcus granulosus expressed protein 0.0379 0.0631 0.0631
Schistosoma mansoni immunophilin 0.0053 0.0043 0.0043
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0956 0.1674 0.1674
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0097 0.0097
Brugia malayi Steroid receptor seven-up type 2 0.0083 0.0097 0.0151
Schistosoma mansoni hypothetical protein 0.0415 0.0696 0.0696
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni nuclear hormone receptor 0.0083 0.0097 0.0097
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0062 0.0059 0.035
Brugia malayi neuropeptide F receptor 0.0075 0.0082 0.0129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0027 0.0027
Leishmania major UDP-galactopyranose mutase 0.0043 0.0024 0.0141
Schistosoma mansoni biogenic amine receptor 0.0075 0.0082 0.0082
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Schistosoma mansoni shc transforming protein 0.1428 0.2527 0.2527
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0141 0.0202 0.1204
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Echinococcus granulosus snurportin 1 0.032 0.0524 0.0524
Echinococcus multilocularis 0.0047 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Echinococcus granulosus tyrosine protein kinase Src64B 0.2385 0.4254 0.4254
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni hypothetical protein 0.0172 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0209 0.0325 0.0367
Echinococcus granulosus tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Loa Loa (eye worm) phosphatidylinositol 3 0.0141 0.0202 0.0228
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0124 0.017 0.0266
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1083 0.1903 0.2966
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.0202 0.0294
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Entamoeba histolytica cysteine surface protein, putative 0.0956 0.1674 0.2608
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0017 0.0027
Echinococcus granulosus tyrosine kinase 0.0956 0.1674 0.1674
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.064 0.1103 0.6589
Echinococcus multilocularis somatostatin receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus expressed conserved protein 0.1428 0.2527 0.2527
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus granulosus fmrfamide receptor 0.0075 0.0082 0.0082
Trypanosoma brucei carbonic anhydrase-like protein 0.0124 0.017 0.0785
Echinococcus granulosus tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0082 0.0082
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0082 0.0082
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Brugia malayi hypothetical protein 0.0037 0.0012 0.0019
Echinococcus multilocularis orexin receptor type 2 0.0075 0.0082 0.0082
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0017 0.0017
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0141 0.0202 0.0202
Brugia malayi G protein-coupled receptor F59B2.13 0.0075 0.0082 0.0129
Echinococcus granulosus peptide allatostatin:somatostatin 0.0075 0.0082 0.0082
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Onchocerca volvulus 0.1428 0.2527 0.5939
Echinococcus granulosus tensin C1 domain containing phosphatase 0.1428 0.2527 0.2527
Echinococcus multilocularis acetylcholinesterase 0.0496 0.0843 0.0843
Brugia malayi ORL1-like opioid receptor 0.0075 0.0082 0.0129
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0158 0.0232 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0083 0.0097 0.0151
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2385 0.4254 0.4254
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Schistosoma mansoni SH2A 0.1428 0.2527 0.2527
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0956 0.1674 0.1674
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0331 0.0498
Brugia malayi hypothetical protein 0.0044 0.0026 0.004
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis dro:myosuppressin receptor 0.0075 0.0082 0.0082
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Echinococcus granulosus tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.3564 0.6384 1
Trichomonas vaginalis CAMK family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0565 0.0966 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0956 0.1674 0.1674
Brugia malayi Carboxylesterase family protein 0.0496 0.0843 0.1321
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0082 0.0082
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Brugia malayi Inositol-1 0.0037 0.0014 0.0022
Trypanosoma brucei Flagellum attachment zone protein 20 0.0956 0.1674 0.7755
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0048 0.0048
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0017 0.0027
Brugia malayi tRNA modification GTPase TrmE family protein 0.1428 0.2527 0.3958
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus tyrosine protein kinase HCK 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0269 0.0432 0.0656
Schistosoma mansoni hypothetical protein 0.0172 0.0257 0.0257
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Schistosoma mansoni cpg binding protein 0.0062 0.0059 0.0059
Schistosoma mansoni hypothetical protein 0.0037 0.0012 0.0012
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0083 0.0097 0.0151
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni hypothetical protein 0.0522 0.089 0.089
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0082 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0097 0.0151
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Giardia lamblia Kinase, NEK 0.0956 0.1674 0.4734
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0012 0.0012
Loa Loa (eye worm) serine/threonine protein kinase 0.0956 0.1674 0.189
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni thyroid hormone receptor 0.0355 0.0588 0.0588
Echinococcus multilocularis serine protein kinase ATM 0.0158 0.0232 0.0232
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0053 0.0043 0.0281
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0158 0.0232 0.0232
Onchocerca volvulus 0.0039 0.0017 0.0041
Echinococcus granulosus allatostatin A receptor 0.0075 0.0082 0.0082
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.0082 0.0082
Schistosoma mansoni tyrosine kinase 0.1004 0.176 0.176
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0178 0.0268 0.0268
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0083 0.0097 0.0097
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis tyrosine protein kinase Src42A 0.2385 0.4254 0.4254
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0269 0.0432 0.258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0318 0.0478
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0075 0.0082 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus protein kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0331 0.0498
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0027 0.0027
Schistosoma mansoni coup transcription factor 0.0083 0.0097 0.0097
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1004 0.176 0.176
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0067 0.0067
Entamoeba histolytica hypothetical protein 0.2931 0.5241 0.8206
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0141 0.0202 0.0202
Echinococcus granulosus serotonin transporter 0.0153 0.0223 0.0223
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0141 0.0202 0.0316
Schistosoma mansoni tensin-related 0.1428 0.2527 0.2527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0224 0.0351 0.0529
Onchocerca volvulus 0.0956 0.1674 0.3935
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0043 0.0024 0.0093
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0269 0.0432 0.1999
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0017 0.0017
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Schistosoma mansoni hypothetical protein 0.0272 0.0438 0.0438
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) steroid hormone receptor 0.0083 0.0097 0.0109
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0014 0.0014
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Echinococcus granulosus tyrosine kinase 0.2385 0.4254 0.4254
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Onchocerca volvulus 0.1428 0.2527 0.5939
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0053 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0017 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0238 0.0351
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0053 0.0043 0.0045
Giardia lamblia Kinase 0.0956 0.1674 0.4734
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0053 0.0043 0.0043
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1037 0.1819 0.1819
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi Carboxylesterase family protein 0.0084 0.0098 0.0153
Onchocerca volvulus 0.0075 0.0082 0.0193
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.1428 0.2527 0.2527
Brugia malayi Dopamine receptor 0.0075 0.0082 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0097 0.0151
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi photoreceptor-specific nuclear receptor 0.0083 0.0097 0.0151
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0026 0.004
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0075 0.0082 0.0082
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0269 0.0432 0.0676
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0141 0.0202 0.1204
Loa Loa (eye worm) hypothetical protein 0.0049 0.0034 0.0038
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0043 0.0024 0.0024
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0014 0.0014
Echinococcus granulosus tyrosine protein kinase csk 0.0956 0.1674 0.1674
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0017 0.0017
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0053 0.0043 0.0048
Echinococcus granulosus neuroligin 0.0084 0.0098 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0214 0.0333 0.05
Entamoeba histolytica tyrosin kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) RhoGAP domain-containing protein 0.1428 0.2527 0.2853
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.1428 0.2527 0.2527
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Trichomonas vaginalis fk506-binding protein, putative 0.0053 0.0043 0.0045
Echinococcus granulosus tyrosine protein kinase Lyn 0.2385 0.4254 0.4254
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni suppressor of cytokine signaling 0.1428 0.2527 0.2527
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0178 0.0268 0.0399
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0075 0.0082 0.0082
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0067 0.0084
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Plasmodium falciparum tyrosine kinase-like protein 0.0956 0.1674 1
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0017 0.0017
Schistosoma mansoni alpha-1 adrenergic receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0059 0.0092
Echinococcus multilocularis kinase suppressor of Ras 1 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Echinococcus granulosus geminin 0.0172 0.0257 0.0257
Schistosoma mansoni myosin xvIII 0.0075 0.0082 0.0082
Echinococcus granulosus acetylcholinesterase 0.0496 0.0843 0.0843
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0178 0.0268 0.1603
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0083 0.0097 0.0097
Brugia malayi G-protein coupled receptor 0.0075 0.0082 0.0129
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2385 0.4254 0.4254
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0178 0.0268 0.1241
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2195 0.3911 0.6127
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0097 0.0151
Onchocerca volvulus 0.0075 0.0082 0.0193
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) TK/INSR protein kinase 0.1004 0.176 0.1987
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Echinococcus granulosus tachykinin peptides receptor 99D 0.0075 0.0082 0.0082
Brugia malayi Tachykinin-like peptides receptor 99D 0.0075 0.0082 0.0129
Echinococcus granulosus serotonin receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0214 0.0333 0.05
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0956 0.1674 0.1674
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0592 0.1015 0.6065
Schistosoma mansoni hypothetical protein 0.0049 0.0034 0.0034
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0592 0.1015 0.1015
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0083 0.0097 0.0109
Brugia malayi hypothetical protein 0.0084 0.0098 0.0153
Brugia malayi Variant SH3 domain containing protein 0.1428 0.2527 0.3958
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Onchocerca volvulus 0.0075 0.0082 0.0193
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0027 0.003
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0083 0.0097 0.0097
Loa Loa (eye worm) carboxylesterase 0.0496 0.0843 0.0952
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0956 0.1674 0.1674
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0956 0.1674 0.1674
Echinococcus granulosus g protein coupled receptor 0.0075 0.0082 0.0082
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica protein kinase, putative 0.1428 0.2527 0.3946
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0956 0.1674 0.1674
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0075 0.0082 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0956 0.1674 0.2622
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0592 0.1015 0.6065
Echinococcus granulosus SH2 motif 0.1428 0.2527 0.2527
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0043 0.0045
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0075 0.0082 0.0129
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0082 0.0082
Onchocerca volvulus 0.0043 0.0024 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis tyrosine kinase 0.0956 0.1674 0.1674
Onchocerca volvulus 0.0039 0.0017 0.0041
Echinococcus multilocularis natriuretic peptide receptor 1 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Plasmodium vivax importin-beta 2, putative 0.003 0 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.06 0.1031 0.1031
Onchocerca volvulus 0.0075 0.0082 0.0193
Schistosoma mansoni tensin-related 0.1428 0.2527 0.2527
Onchocerca volvulus 0.0075 0.0082 0.0193
Entamoeba histolytica hypothetical protein 0.0141 0.0202 0.0297
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0052 0.0041 0.0041
Brugia malayi nuclear receptor NHR-88 0.0083 0.0097 0.0151
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus hypothetical protein 0.0075 0.0082 0.0082
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Echinococcus multilocularis FL cytokine receptor 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0024 0.0024
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0522 0.089 0.089
Schistosoma mansoni adapter molecule crk 0.1428 0.2527 0.2527
Loa Loa (eye worm) TK/FAK protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) TK/ROR protein kinase 0.0956 0.1674 0.189
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0053 0.0043 0.0048
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0592 0.1015 0.6065
Echinococcus multilocularis carbonic anhydrase II 0.0124 0.017 0.017
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0053 0.0043 0.0045
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0124 0.017 0.0244
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0017 0.0041
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0027 0.0027
Plasmodium falciparum protein kinase, putative 0.0956 0.1674 1
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.1225 0.2158 0.3366
Onchocerca volvulus 0.0956 0.1674 0.3935
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0269 0.0432 0.0432
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Brugia malayi hypothetical protein 0.1428 0.2527 0.3958
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0956 0.1674 0.2608
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0067 0.0403
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0097 0.0151
Schistosoma mansoni serine/threonine protein kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) RGC/RGC protein kinase 0.0956 0.1674 0.189
Brugia malayi nuclear hormone receptor 0.0039 0.0017 0.0027
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Toxoplasma gondii STE kinase 0.0956 0.1674 1
Onchocerca volvulus 0.2385 0.4254 1
Schistosoma mansoni tyrosine kinase 0.1037 0.1819 0.1819
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0141 0.0202 0.0202
Toxoplasma gondii protein kinase domain-containing protein 0.0956 0.1674 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Brugia malayi nuclear receptor RXR 0.0044 0.0026 0.004
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0017 0.0027
Schistosoma mansoni cpg binding protein 0.0062 0.0059 0.0059
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0053 0.0043 0.0049
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Giardia lamblia Kinase, NEK 0.0956 0.1674 0.4734
Brugia malayi Carboxylesterase family protein 0.0084 0.0098 0.0153
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0075 0.0082 0.0093
Echinococcus granulosus receptor type guanylyl cyclase 0.0956 0.1674 0.1674
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0956 0.1674 0.1674
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0141 0.0202 0.0932
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0956 0.1674 0.7755
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.2195 0.3911 0.4416
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0098 0.0098
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0084 0.0098 0.0132
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.2385 0.4254 0.4254
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.1428 0.2527 0.2527
Schistosoma mansoni hypothetical protein 0.0075 0.0082 0.0082
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0592 0.1015 0.1572
Echinococcus granulosus tyrosine protein kinase Fps85D 0.2385 0.4254 0.4254
Loa Loa (eye worm) phosphatidylinositol kinase 0.0141 0.0202 0.0228
Echinococcus granulosus tyrosine protein kinase Src42A 0.1428 0.2527 0.2527
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0172 0.0172
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0017 0.0017
Brugia malayi Variant SH3 domain containing protein 0.1428 0.2527 0.3958
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0062 0.0059 0.0538
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0059 0.0433
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0082 0.0082
Schistosoma mansoni growth factor receptor-bound protein 0.1428 0.2527 0.2527
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0124 0.017 0.017
Brugia malayi Tyrosine-protein kinase abl-1 0.2385 0.4254 0.6664
Loa Loa (eye worm) phosphatidylinositol 3 0.0269 0.0432 0.0488
Mycobacterium ulcerans dehydrogenase 0.0043 0.0024 0.0093
Treponema pallidum sodium- and chloride- dependent transporter 0.0153 0.0223 1
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Schistosoma mansoni adenoreceptor 0.0075 0.0082 0.0082
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0075 0.0082 0.0082
Echinococcus multilocularis tyrosine protein kinase shark 0.2385 0.4254 0.4254
Onchocerca volvulus 0.1428 0.2527 0.5939
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0269 0.0432 0.0658
Trichomonas vaginalis AGC family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0097 0.0151
Echinococcus multilocularis neuropeptide s receptor 0.0075 0.0082 0.0082
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0075 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0075 0.0082 0.0082
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Trichomonas vaginalis protein kinase atn1, putative 0.0956 0.1674 0.2606
Loa Loa (eye worm) TK protein kinase 0.2385 0.4254 0.4804
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1428 0.2527 0.2527
Entamoeba histolytica receptor protein kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni serine/threonine RGC 0.0956 0.1674 0.1674
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0082 0.0082
Schistosoma mansoni inositol monophosphatase 0.0037 0.0014 0.0014
Echinococcus multilocularis heat shock protein 70 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus multilocularis SHC transforming protein 3 0.1428 0.2527 0.2527
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Schistosoma mansoni protein tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0082 0.0082
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0495 0.0841 0.095
Plasmodium vivax tyrosine kinase-like protein, putative 0.0956 0.1674 1
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis para nitrobenzyl esterase 0.0084 0.0098 0.0098
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0083 0.0097 0.0109
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.3564 0.6384 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0956 0.1674 0.2622
Toxoplasma gondii protein kinase 0.0956 0.1674 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0017 0.0017
Giardia lamblia Hypothetical protein 0.0141 0.0202 0.046
Loa Loa (eye worm) hypothetical protein 0.0161 0.0238 0.0268
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus carbonic anhydrase II 0.0124 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Echinococcus multilocularis tyrosine protein kinase HCK 0.0956 0.1674 0.1674
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0956 0.1674 0.2622
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Echinococcus multilocularis g-protein coupled receptor 0.0075 0.0082 0.0082
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Trypanosoma cruzi protein kinase, putative 0.0956 0.1674 0.2606
Onchocerca volvulus 0.0075 0.0082 0.0193
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Brugia malayi RE15519p 0.0075 0.0082 0.0129
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0082 0.0093
Schistosoma mansoni acetylcholinesterase 0.0084 0.0098 0.0098
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0214 0.0333 0.05
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1428 0.2527 0.2527
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0044 0.005
Echinococcus multilocularis SH2 domain containing protein 7 0.1428 0.2527 0.2527
Mycobacterium leprae conserved hypothetical protein 0.0141 0.0202 1
Leishmania major phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.1204
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0956 0.1674 0.1674
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0956 0.1674 0.2608
Schistosoma mansoni tyrosine protein kinase 0.0956 0.1674 0.1674
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0083 0.0097 0.0151
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) phosphatidylinositol 3 0.0141 0.0202 0.0228
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0075 0.0082 0.0082
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0158 0.0232 0.0232
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0956 0.1674 0.7755
Trichomonas vaginalis immunophilin, putative 0.0053 0.0043 0.0045
Schistosoma mansoni hypothetical protein 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1004 0.176 0.176
Loa Loa (eye worm) solute carrier family 6 member 4 0.0153 0.0223 0.0252
Onchocerca volvulus 0.0075 0.0082 0.0193
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.1428 0.2527 0.2527
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni growth hormone secretagogue receptor 0.0075 0.0082 0.0082
Entamoeba histolytica SH2-protein kinase domain containing protein 0.1428 0.2527 0.3946
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Leishmania major peptidylprolyl isomerase-like protein 0.0053 0.0043 0.0257
Onchocerca volvulus 0.0075 0.0082 0.0193
Brugia malayi Dopamine receptor protein 2 0.0075 0.0082 0.0129
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Brugia malayi hypothetical protein 0.0956 0.1674 0.2622
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0084
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0272 0.0438 0.0438
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0017 0.0017
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.2385 0.4254 0.4254
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0024 0.0174
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0319 0.0478
Onchocerca volvulus 0.0084 0.0098 0.023
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0043 0.0024 0.0855
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0083 0.0097 0.0151
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0083 0.0097 0.0109
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis tyrosine protein kinase pr2 0.0956 0.1674 0.1674
Schistosoma mansoni immunophilin 0.0046 0.003 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Schistosoma mansoni opsin-like receptor 0.0075 0.0082 0.0082
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1562 0.2768 0.4325
Echinococcus granulosus neuropeptide receptor 0.0075 0.0082 0.0082
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0269 0.0432 0.0658
Echinococcus multilocularis tyrosine protein kinase csk 0.0956 0.1674 0.1674
Echinococcus multilocularis BC026374 protein (S09 family) 0.0084 0.0098 0.0098
Brugia malayi Receptor family ligand binding region containing protein 0.0956 0.1674 0.2622
Plasmodium falciparum protein kinase, putative 0.0956 0.1674 1
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0082 0.0093
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0046 0.003 0.003
Mycobacterium ulcerans monoamine oxidase 0.0043 0.0024 0.0093
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0043 0.0197
Echinococcus multilocularis G-protein coupled receptor, putative 0.0075 0.0082 0.0082
Onchocerca volvulus 0.0075 0.0082 0.0193
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.1225 0.2158 0.3366
Loa Loa (eye worm) STAT protein 0.1428 0.2527 0.2853
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0496 0.0843 0.0952
Loa Loa (eye worm) TK/EPH protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0075 0.0082 0.0082
Leishmania major protein kinase, putative 0.0956 0.1674 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0956 0.1674 0.1674
Echinococcus multilocularis serotonin receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) SRC-1 0.2385 0.4254 0.4804
Echinococcus multilocularis SH2 motif 0.1428 0.2527 0.2527
Echinococcus multilocularis tensin 0.1428 0.2527 0.2527
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0075 0.0082 0.0093
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0774 0.1345 0.3779
Schistosoma mansoni cpg binding protein 0.0059 0.0053 0.0053
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0043 0.0024 0.0024
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0124 0.017 0.0192
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Echinococcus multilocularis N chimaerin 0.1428 0.2527 0.2527
Toxoplasma gondii FATC domain-containing protein 0.0158 0.0232 0.1387
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus g protein coupled receptor 0.0075 0.0082 0.0082
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0082 0.0082
Leishmania major fk506-binding protein 1-like protein 0.0053 0.0043 0.0257
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0012 0.0012
Schistosoma mansoni gliotactin 0.0084 0.0098 0.0098
Loa Loa (eye worm) phosphatidylinositol 3 0.4932 0.8857 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0269 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Giardia lamblia Protein 21.1 0.0956 0.1674 0.4734
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0082 0.0082
Entamoeba histolytica hypothetical protein 0.0141 0.0202 0.0297
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Entamoeba histolytica hypothetical protein, conserved 0.0956 0.1674 0.2608
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0956 0.1674 0.2606
Echinococcus granulosus fibroblast growth factor receptor 4 0.0956 0.1674 0.1674
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.064 0.1103 0.1103
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0043 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0053 0.0043 0.0045
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0082 0.0082
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) carboxylesterase 0.0084 0.0098 0.0111
Echinococcus multilocularis protein kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Schistosoma mansoni tyrosine kinase 0.008 0.0092 0.0092
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0026 0.004
Brugia malayi Guanylyl cyclase protein 23 0.0956 0.1674 0.2622
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0083 0.0097 0.0151
Trypanosoma brucei Pseudokinase, putative 0.0956 0.1674 0.7755
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus granulosus acetylcholinesterase 0.0496 0.0843 0.0843
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0158 0.0232 0.0343
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis protein tyrosine kinase, putative 0.0956 0.1674 0.2606
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus multilocularis c src tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.1428 0.2527 0.2527
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0017 0.0017
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Echinococcus granulosus retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Echinococcus granulosus tyrosine protein kinase csk 0.0956 0.1674 0.1674
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0067 0.0084
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0075 0.0082 0.0129
Echinococcus granulosus activated cdc42 kinase 1 0.0956 0.1674 0.1674
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0017 0.0017
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0046 0.003 0.018
Echinococcus granulosus g protein coupled receptor 0.0075 0.0082 0.0082
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Brugia malayi hypothetical protein 0.0043 0.0024 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1225 0.2158 0.3381
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0492 0.0836 0.0836
Brugia malayi putative neuropeptide receptor NPR1 0.0075 0.0082 0.0129
Schistosoma mansoni neuropeptide receptor 0.0075 0.0082 0.0082
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0956 0.1674 0.1674
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0956 0.1674 0.1674
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0053 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0083 0.0097 0.0151
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.0202 0.0294
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0053 0.0043 0.0257
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1428 0.2527 0.2527
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Echinococcus multilocularis sex peptide receptor 0.0075 0.0082 0.0082
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi nuclear receptor NHR-88 0.0039 0.0017 0.0027
Schistosoma mansoni hypothetical protein 0.0075 0.0082 0.0082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0027 0.0027
Brugia malayi Variant SH3 domain containing protein 0.1428 0.2527 0.3958
Brugia malayi RNA, U transporter 1 0.0085 0.01 0.0157
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0027 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0956 0.1674 0.1674
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0043 0.0024 0.0141
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Echinococcus multilocularis cpg binding protein 0.0062 0.0059 0.0059
Echinococcus granulosus insulin receptor 0.1004 0.176 0.176
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0178 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Schistosoma mansoni tensin 0.1428 0.2527 0.2527
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus kinase suppressor of Ras 1 0.0956 0.1674 0.1674
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Brugia malayi tailless protein 0.0039 0.0017 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus SHC transforming protein 3 0.1428 0.2527 0.2527
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Echinococcus granulosus ephrin type A receptor 4 A 0.0956 0.1674 0.1674
Schistosoma mansoni inositol monophosphatase 0.0037 0.0014 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0027 0.0027
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis acetylcholinesterase 0.0496 0.0843 0.0843
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0026 0.0026
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.2385 0.4254 0.4254
Onchocerca volvulus 0.0956 0.1674 0.3935
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.064 0.1103 0.1709
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.2593 0.4631 0.7248
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0098 0.0098
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0956 0.1674 0.1674
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0017 0.002
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0269 0.0432 0.0656
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.064 0.1103 0.1709
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0067 0.0086
Plasmodium vivax hypothetical protein 0.0141 0.0202 0.1204
Loa Loa (eye worm) SH2 domain-containing protein 0.1428 0.2527 0.2853
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Leishmania major protein kinase, putative 0.0956 0.1674 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0319 0.0478
Echinococcus multilocularis protein KINase family member (kin 25) 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0158 0.0232 0.0343
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Schistosoma mansoni amine oxidase 0.0043 0.0024 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0053 0.0043 0.0197
Schistosoma mansoni hypothetical protein 0.032 0.0524 0.0524
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0082 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0956 0.1674 0.2622
Leishmania major carbonic anhydrase-like protein 0.0124 0.017 0.1014
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0067 0.031
Onchocerca volvulus 0.0084 0.0098 0.023
Loa Loa (eye worm) hypothetical protein 0.0153 0.0223 0.0252
Onchocerca volvulus 0.0084 0.0098 0.023
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1428 0.2527 0.3958
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0075 0.0082 0.0129
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0189 0.0288 0.1332
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0956 0.1674 0.189
Brugia malayi steroid hormone receptor 0.0083 0.0097 0.0151
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.2002 0.3562 0.558
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi protein-tyrosine kinase 0.2385 0.4254 0.6664
Onchocerca volvulus 0.0141 0.0202 0.0474
Loa Loa (eye worm) TK/CSK protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni zinc finger protein 0.0039 0.0017 0.0017
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0017 0.0041
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0956 0.1674 0.1674
Mycobacterium ulcerans oxidoreductase 0.0043 0.0024 0.0093
Echinococcus multilocularis serotonin transporter 0.0153 0.0223 0.0223
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1428 0.2527 0.2527
Echinococcus multilocularis tyrosine protein kinase 0.0956 0.1674 0.1674
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0141 0.0202 0.1204
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.1428 0.2527 0.5939
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0956 0.1674 1
Entamoeba histolytica ankyrin repeat protein 0.0956 0.1674 0.2608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0269 0.0432 0.0656
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.032 0.0524 0.0591
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0956 0.1674 0.2622
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0082 0.0082
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Loa Loa (eye worm) SH2 domain-containing protein 0.1428 0.2527 0.2853
Echinococcus multilocularis growth factor receptor bound protein 2 0.1428 0.2527 0.2527
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0059 0.0059
Leishmania major phosphatidylinositol kinase related protein, putative 0.0141 0.0202 0.1204
Brugia malayi putative neuropeptide receptor 0.0075 0.0082 0.0129
Echinococcus granulosus epidermal growth factor receptor 0.1107 0.1946 0.1946
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0014 0.5
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.0153 0.0223 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0319 0.0478
Onchocerca volvulus 0.0956 0.1674 0.3935
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.3564 0.6384 1
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Brugia malayi nuclear receptor NHR-67 0.0039 0.0017 0.0027
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0158 0.0232 0.0343
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis SH2 motif 0.1428 0.2527 0.2527
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.079 0.1373 0.1373
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.2385 0.4254 0.4254
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0017 0.0027
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0141 0.0202 0.0228
Echinococcus multilocularis tyrosine protein kinase Blk 0.2385 0.4254 0.4254
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0084 0.0098 0.0098
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis FTZ F1 alpha 0.0083 0.0097 0.0097
Onchocerca volvulus 0.0075 0.0082 0.0193
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0141 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Echinococcus granulosus tyrosine protein kinase csk 0.0956 0.1674 0.1674
Schistosoma mansoni neuroligin 3 (S09 family) 0.0084 0.0098 0.0098
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.3564 0.6384 1
Echinococcus granulosus dro:myosuppressin receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis neuroligin 0.0084 0.0098 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis serotonin receptor 0.0075 0.0082 0.0082
Echinococcus granulosus 7tm_1 domain containing protein 0.0075 0.0082 0.0082
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0075 0.0082 0.0082
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni hypothetical protein 0.1428 0.2527 0.2527
Loa Loa (eye worm) hypothetical protein 0.0496 0.0843 0.0952
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.064 0.1103 0.5109
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.1204
Echinococcus multilocularis signal transduction protein lnk realted 0.1428 0.2527 0.2527
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.1961 0.3488 1
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus granulosus dnaJ subfamily B 0.0415 0.0696 0.0696
Entamoeba histolytica SH2-protein kinase domain containing protein 0.2385 0.4254 0.6658
Echinococcus multilocularis insulin receptor 0.1004 0.176 0.176
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1225 0.2158 0.3366
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.064 0.1103 0.1103
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0043 0.0024 0.0024
Loa Loa (eye worm) norepinephrine transporter 0.0153 0.0223 0.0252
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1428 0.2527 0.2853
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0956 0.1674 0.2606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Echinococcus multilocularis tyrosine protein kinase Fgr 0.2385 0.4254 0.4254
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.1428 0.2527 0.2853
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.003 0 0.0001
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.5565 1 1
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.0097 0.0151
Toxoplasma gondii histone lysine-specific demethylase 0.0043 0.0024 0.0141
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Onchocerca volvulus Neuropeptide F receptor homolog 0.0075 0.0082 0.0193
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0269 0.0432 0.1999
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Loa Loa (eye worm) carbonic anhydrase 3 0.0124 0.017 0.0192
Onchocerca volvulus 0.2385 0.4254 1
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Brugia malayi ecdysteroid receptor 0.0083 0.0097 0.0151
Loa Loa (eye worm) FKBP5 protein 0.0053 0.0043 0.0049
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis activin receptor type 0.0956 0.1674 0.1674
Brugia malayi Dopamine receptor protein 1 0.0075 0.0082 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0319 0.0478
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.3564 0.6384 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0178 0.0268 0.1603
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.3564 0.6384 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0956 0.1674 0.3935
Schistosoma mansoni sodium/chloride dependent transporter 0.0153 0.0223 0.0223
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0083 0.0097 0.0097
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0024 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0269 0.0432 0.0656
Echinococcus granulosus alpha 1A adrenergic receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) carboxylesterase 0.0084 0.0098 0.0111
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.1428 0.2527 0.2527
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0014 0.0084
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.3564 0.6384 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2385 0.4254 0.4254
Echinococcus multilocularis Zinc finger, PHD finger 0.0592 0.1015 0.1015
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0017 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0956 0.1674 0.1674
Brugia malayi hypothetical protein 0.0039 0.0017 0.0027
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0124 0.017 0.0266
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0024 0.0015
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0141 0.0202 0.1204
Schistosoma mansoni neuropeptide receptor 0.0075 0.0082 0.0082
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0956 0.1674 0.1674
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Loa Loa (eye worm) TK/ALK protein kinase 0.0956 0.1674 0.189
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Echinococcus multilocularis SH2 motif 0.1428 0.2527 0.2527
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0043 0.0024 0.0141
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.2931 0.5241 0.8206
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0141 0.0202 0.0294
Schistosoma mansoni steroid hormone receptor ad4bp 0.0083 0.0097 0.0097
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Brugia malayi Sex muscle abnormal protein 5 0.1428 0.2527 0.3958
Mycobacterium tuberculosis Possible oxidoreductase 0.0043 0.0024 0.0174
Onchocerca volvulus 0.1428 0.2527 0.5939
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0017 0.0017
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Schistosoma mansoni neuropeptide receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0026 0.0026
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Brugia malayi SWIRM domain containing protein 0.0043 0.0024 0.0037
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Echinococcus granulosus somatostatin receptor 0.0075 0.0082 0.0082
Brugia malayi Importin beta-1 subunit 0.003 0 0.0001
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0012 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.06 0.1031 0.1031
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0083 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Giardia lamblia GTOR 0.0269 0.0432 0.1129
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Onchocerca volvulus 0.0141 0.0202 0.0474
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Onchocerca volvulus 0.0956 0.1674 0.3935
Loa Loa (eye worm) hypothetical protein 0.0158 0.0232 0.0262
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0241 0.0382 0.1767
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0027 0.0027
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0083 0.0097 0.0097
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0956 0.1674 0.2606
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Onchocerca volvulus 0.0209 0.0325 0.0763
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0017 0.0017
Echinococcus granulosus ecdysone induced protein 78C 0.0083 0.0097 0.0097
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0027
Echinococcus granulosus tyrosine protein kinase 0.0956 0.1674 0.1674
Plasmodium vivax hypothetical protein, conserved 0.0141 0.0202 0.1204
Brugia malayi CXXC zinc finger family protein 0.0059 0.0053 0.0083
Schistosoma mansoni hypothetical protein 0.0075 0.0082 0.0082
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0084 0.0098 0.0098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi Variant SH3 domain containing protein 0.1428 0.2527 0.3958
Echinococcus granulosus growth factor receptor bound protein 2 0.1428 0.2527 0.2527
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0956 0.1674 0.2606
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0062 0.0059 0.0059
Brugia malayi nuclear receptor RXR 0.0039 0.0017 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni growth factor receptor-bound protein 0.1428 0.2527 0.2527
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0083 0.0097 0.0097
Brugia malayi conserved hypotetical protein 0.0039 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Schistosoma mansoni nuclear receptor 0.0039 0.0017 0.0017
Echinococcus granulosus neuropeptide FF receptor 2 0.0075 0.0082 0.0082
Echinococcus multilocularis SH2 domain containing adapter protein F 0.1428 0.2527 0.2527
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0148 0.0885
Onchocerca volvulus 0.0075 0.0082 0.0193
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Onchocerca volvulus 0.0153 0.0223 0.0525
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.064 0.1103 0.1709
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0053 0.0043 0.0257
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1225 0.2158 0.3368
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0026 0.0029
Onchocerca volvulus 0.2385 0.4254 1
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0592 0.1015 0.6065
Echinococcus multilocularis raf serine:threonine protein kinase 0.0956 0.1674 0.1674
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0956 0.1674 0.1674
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0269 0.0432 0.258
Echinococcus granulosus neuropeptide receptor 0.0075 0.0082 0.0082
Schistosoma mansoni RAR-like nuclear receptor 0.0083 0.0097 0.0097
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0161 0.0238 0.1419
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0153 0.0223 0.0223
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Mycobacterium tuberculosis Carboxylesterase LipT 0.0084 0.0098 0.0948
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0956 0.1674 0.1674
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0083 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0082 0.0082
Brugia malayi Raf kinase 0.0956 0.1674 0.2622
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Brugia malayi hypothetical protein 0.0049 0.0034 0.0053
Onchocerca volvulus 0.0059 0.0053 0.0124
Echinococcus multilocularis epidermal growth factor receptor 0.1107 0.1946 0.1946
Brugia malayi Serotonin receptor 0.0075 0.0082 0.0129
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Trypanosoma brucei protein kinase, putative 0.0956 0.1674 0.7755
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0067 0.0106
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0083 0.0097 0.0097
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0075 0.0082 0.0193
Brugia malayi Immunoglobulin I-set domain containing protein 0.0956 0.1674 0.2622
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0097 0.0151
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.2385 0.4254 0.4254
Loa Loa (eye worm) RGC/RGC protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni fkbp-rapamycin associated protein 0.0158 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0046 0.003 0.0034
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus FTZ F1 alpha 0.0083 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi SRC-1 0.2385 0.4254 0.6664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0024 0.0141
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.2385 0.4254 0.4254
Echinococcus multilocularis epidermal growth factor receptor 0.1037 0.1819 0.1819
Schistosoma mansoni biogenic amine receptor 0.0075 0.0082 0.0082
Plasmodium falciparum protein kinase, putative 0.0956 0.1674 1
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Echinococcus multilocularis neuropeptide FF receptor 2 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0495 0.0841 0.095
Brugia malayi hypothetical protein 0.0956 0.1674 0.2622
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0124 0.017 0.0244
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0956 0.1674 0.1674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0158 0.0232 0.0343
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Loa Loa (eye worm) acetylcholinesterase 1 0.0496 0.0843 0.0952
Plasmodium vivax tyrosine kinase-like protein, putative 0.0956 0.1674 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0268 0.0399
Schistosoma mansoni protein kinase 0.0956 0.1674 0.1674
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0082 0.0082
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0141 0.0202 0.0202
Entamoeba histolytica hypothetical protein 0.0158 0.0232 0.0345
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0053 0.0043 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0158 0.0232 0.0364
Brugia malayi C-terminal src kinase protein 1 0.0956 0.1674 0.2622
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Trichomonas vaginalis PIKK family atypical protein kinase 0.0221 0.0346 0.052
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0141 0.0202 0.0294
Brugia malayi G protein-coupled receptor 0.0075 0.0082 0.0129
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0592 0.1015 0.1015
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0141 0.0202 0.0294
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0197 0.0302 0.1398
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0024 0.0015
Echinococcus multilocularis protein kinase 0.0956 0.1674 0.1674
Trichomonas vaginalis spcc417.12 protein, putative 0.0084 0.0098 0.0132
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0607 0.1043 1
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.1204
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0269 0.0432 0.0432
Trichomonas vaginalis PIKK family atypical protein kinase 0.0169 0.0252 0.0373
Schistosoma mansoni BC026374 protein (S09 family) 0.0084 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi Protein kinase domain containing protein 0.2385 0.4254 0.6664
Echinococcus granulosus G protein coupled receptor 139 0.0075 0.0082 0.0082
Echinococcus multilocularis suppressor of cytokine signaling 6 0.1428 0.2527 0.2527
Loa Loa (eye worm) inositol-1 0.0037 0.0014 0.0016
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Brugia malayi amine oxidase, flavin-containing family protein 0.0043 0.0024 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0141 0.0202 0.0316
Loa Loa (eye worm) phosphatidylinositol 3 0.1083 0.1903 0.2149
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0141 0.0202 0.0202
Echinococcus granulosus N chimaerin 0.1428 0.2527 0.2527
Echinococcus multilocularis 0.0141 0.0202 0.0202
Onchocerca volvulus Protein ultraspiracle homolog 0.0083 0.0097 0.0227
Loa Loa (eye worm) RGC/RGC protein kinase 0.0956 0.1674 0.189
Brugia malayi SH2 domain containing protein 0.2385 0.4254 0.6664
Trichomonas vaginalis STE family protein kinase 0.0956 0.1674 0.2606
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0141 0.0202 0.0297
Echinococcus granulosus tensin 0.1428 0.2527 0.2527
Brugia malayi Protein kinase domain containing protein 0.1004 0.176 0.2757
Echinococcus multilocularis ephrin type A receptor 4 A 0.0956 0.1674 0.1674
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0124 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Brugia malayi Carboxylesterase family protein 0.0496 0.0843 0.1321
Echinococcus multilocularis thyroid hormone receptor alpha 0.0355 0.0588 0.0588
Schistosoma mansoni tyrosine kinase 0.008 0.0092 0.0092
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0049 0.0034 0.0038
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0956 0.1674 0.2606
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0046 0.003 0.003
Loa Loa (eye worm) RGC/RGC protein kinase 0.0956 0.1674 0.189
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0592 0.1015 0.1574
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Brugia malayi ephrin receptor 1 precursor 0.0956 0.1674 0.2622
Echinococcus granulosus 7TM GPCR rhodopsin 0.0075 0.0082 0.0082
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.064 0.1103 0.1712
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.3422 0.6129 0.9599
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0496 0.0843 0.0843
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0027 0.0027
Schistosoma mansoni signal transduction protein lnk-related 0.1428 0.2527 0.2527
Loa Loa (eye worm) TK/Met protein kinase 0.0956 0.1674 0.189
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0158 0.0232 0.0364
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0241 0.0382 0.228
Onchocerca volvulus 0.0083 0.0097 0.0227
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0067 0.0067
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0075 0.0082 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0097 0.0097
Onchocerca volvulus 0.0084 0.0098 0.023
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0043 0.0024 0.0141
Leishmania major phosphatidylinositol 3-kinase, putative 0.0592 0.1015 0.6065
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Leishmania major hypothetical protein, conserved 0.0956 0.1674 1
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Onchocerca volvulus 0.0956 0.1674 0.3935
Chlamydia trachomatis protoporphyrinogen oxidase 0.0043 0.0024 0.5
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.5565 1 1
Schistosoma mansoni lipoxygenase 0.0056 0.0048 0.0048
Echinococcus multilocularis NCK adaptor protein 0.1428 0.2527 0.2527
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0083 0.0097 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0141 0.0202 0.0932
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0097 0.0097
Echinococcus multilocularis carboxylesterase 5A 0.0496 0.0843 0.0843
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi Serotonin receptor 0.0075 0.0082 0.0129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0083 0.0097 0.0109
Echinococcus multilocularis tensin 0.1428 0.2527 0.2527
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Echinococcus multilocularis fk506 binding protein 0.0053 0.0043 0.0043
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0083 0.0097 0.0097
Brugia malayi RhoGAP domain containing protein 0.1428 0.2527 0.3958
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0084 0.0098 0.0948
Brugia malayi SH2 domain containing protein 0.1428 0.2527 0.3958
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0956 0.1674 0.189
Brugia malayi Furin-like cysteine rich region family protein 0.1107 0.1946 0.3048
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0083 0.0097 0.0097
Onchocerca volvulus 0.0084 0.0098 0.023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0956 0.1674 0.2608
Loa Loa (eye worm) DR-78 0.0039 0.0017 0.002
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus multilocularis ecdysone induced protein 78C 0.0083 0.0097 0.0097
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0956 0.1674 0.1674
Echinococcus granulosus suppressor of cytokine signaling 7 0.1428 0.2527 0.2527
Trypanosoma cruzi target of rapamycin kinase 3 0.0241 0.0382 0.0577
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0082 0.0093
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0956 0.1674 0.2606
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0272 0.0438 0.0438
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1428 0.2527 0.2527
Brugia malayi bone morphogenetic protein type 1 receptor 0.0956 0.1674 0.2622
Schistosoma mansoni tyrosine kinase 0.2385 0.4254 0.4254
Loa Loa (eye worm) serotonin transporter b 0.0153 0.0223 0.0252
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0082 0.0082
Onchocerca volvulus Bile acid receptor homolog 0.0083 0.0097 0.0227
Echinococcus granulosus tyrosine protein kinase Srms 0.2385 0.4254 0.4254
Schistosoma mansoni nuclear receptor 0.0039 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0109
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis transfer RNA-Thr 0.0956 0.1674 0.1674
Echinococcus granulosus carboxylesterase 5A 0.0496 0.0843 0.0843
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0178 0.0268 0.0399
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.2195 0.3911 0.3911
Entamoeba histolytica receptor protein kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica tyrosin kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0075 0.0082 0.0082
Echinococcus granulosus epidermal growth factor receptor 0.1037 0.1819 0.1819
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.019 0.0289 0.1728
Entamoeba histolytica serine/threonine kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0382 0.0577
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Trichomonas vaginalis TK family protein kinase 0.0956 0.1674 0.2606
Brugia malayi Melatonin receptor type 1A 0.0075 0.0082 0.0129
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0158 0.0232 0.1074
Schistosoma mansoni tyrosine kinase 0.008 0.0092 0.0092
Echinococcus granulosus BC026374 protein S09 family 0.0084 0.0098 0.0098
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0141 0.0202 0.0294
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0141 0.0202 0.0316
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0956 0.1674 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0178 0.0268 0.0303
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Toxoplasma gondii target of rapamycin (TOR), putative 0.0234 0.0369 0.2203
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0082 0.0082
Giardia lamblia Phosphatidylinositol 4-kinase 0.0141 0.0202 0.046
Brugia malayi hypothetical protein 0.0075 0.0082 0.0129
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus multilocularis 0.0043 0.0024 0.0024
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0956 0.1674 0.189
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0097 0.0097
Echinococcus granulosus g-protein coupled receptor 0.0075 0.0082 0.0082
Echinococcus granulosus retinal guanylyl cyclase 2 0.0956 0.1674 0.1674
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0082 0.0082
Loa Loa (eye worm) melatonin receptor type 1A 0.0075 0.0082 0.0093
Brugia malayi G-protein coupled receptor 0.0075 0.0082 0.0129
Brugia malayi sulfakinin receptor protein 0.0075 0.0082 0.0129
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0141 0.0202 0.0202
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0082 0.0093
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0026 0.0026
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Schistosoma mansoni nck2/grb4 0.1428 0.2527 0.2527
Schistosoma mansoni vav2 0.1428 0.2527 0.2527
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Schistosoma mansoni hypothetical protein 0.1428 0.2527 0.2527
Echinococcus granulosus natriuretic peptide receptor 1 0.0956 0.1674 0.1674
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0607 0.1043 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Entamoeba histolytica tyrosin kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus integrin linked protein kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Loa Loa (eye worm) TK/ACK protein kinase 0.0956 0.1674 0.189
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0017 0.0017
Leishmania major hypothetical protein, conserved 0.0141 0.0202 0.1204
Brugia malayi Tyrosine-protein kinase PR2 0.0956 0.1674 0.2622
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0956 0.1674 0.2608
Echinococcus multilocularis protein tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Echinococcus granulosus activated cdc42 kinase 1 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Trichomonas vaginalis conserved hypothetical protein 0.0956 0.1674 0.2606
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0956 0.1674 0.2622
Echinococcus multilocularis snurportin 1 0.032 0.0524 0.0524
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1225 0.2158 0.3368
Schistosoma mansoni ephrin receptor 0.0956 0.1674 0.1674
Brugia malayi Tensin 0.1428 0.2527 0.3958
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0029
Echinococcus granulosus tyrosine kinase 0.2385 0.4254 0.4254
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.1428 0.2527 0.5939
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0083 0.0097 0.0097
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0956 0.1674 0.3935
Schistosoma mansoni amine oxidase 0.0043 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Schistosoma mansoni retinoic acid receptor RXR 0.0083 0.0097 0.0097
Echinococcus multilocularis 0.1428 0.2527 0.2527
Entamoeba histolytica SH2 domain containing protein 0.1428 0.2527 0.3946
Schistosoma mansoni amine GPCR 0.0075 0.0082 0.0082
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0082 0.0082
Echinococcus granulosus tyrosine protein kinase Src42A 0.2385 0.4254 0.4254
Echinococcus multilocularis geminin 0.0172 0.0257 0.0257
Brugia malayi integrin-linked kinase 0.0956 0.1674 0.2622
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Brugia malayi SH2 domain containing protein 0.2385 0.4254 0.6664
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0158 0.0232 0.0343
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0053 0.0043 0.0043
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0956 0.1674 0.1674
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0141 0.0202 0.1204
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0141 0.0202 0.0202
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0017 0.0017
Schistosoma mansoni thyroid hormone receptor 0.0355 0.0588 0.0588
Loa Loa (eye worm) protein kinase domain-containing protein 0.0956 0.1674 0.189
Echinococcus granulosus hypothetical protein 0.1428 0.2527 0.2527
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0017 0.0017
Schistosoma mansoni histamine h1 receptor 0.0075 0.0082 0.0082
Brugia malayi hypothetical protein 0.2385 0.4254 0.6664
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Schistosoma mansoni tyrosine kinase 0.1037 0.1819 0.1819
Loa Loa (eye worm) hypothetical protein 0.0084 0.0098 0.0111
Schistosoma mansoni suppressor of cytokine signaling 0.1428 0.2527 0.2527
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1428 0.2527 0.2527
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0956 0.1674 1
Brugia malayi ecdysone receptor 0.0039 0.0017 0.0027
Schistosoma mansoni tyrosine kinase 0.1004 0.176 0.176
Schistosoma mansoni neuropeptide f receptor 76f 0.0075 0.0082 0.0082
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.002
Loa Loa (eye worm) TK protein kinase 0.0956 0.1674 0.189
Echinococcus granulosus SH2 domain containing protein 7 0.1428 0.2527 0.2527
Loa Loa (eye worm) sex muscle abnormal protein 5 0.1428 0.2527 0.2853
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.0082 0.0082
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0083 0.0097 0.0151
Brugia malayi neuropeptide F receptor 0.0075 0.0082 0.0129
Onchocerca volvulus 0.0075 0.0082 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Schistosoma mansoni tensin 0.1428 0.2527 0.2527
Brugia malayi cytokine inducible SH2-containing protein 5 0.1428 0.2527 0.3958
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0083 0.0097 0.0227
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0075 0.0082 0.0129
Echinococcus multilocularis allatostatin A receptor 0.0075 0.0082 0.0082
Echinococcus multilocularis tyrosine protein kinase csk 0.0956 0.1674 0.1674
Echinococcus granulosus neuropeptide receptor A26 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Plasmodium falciparum protoporphyrinogen oxidase 0.0043 0.0024 0.0141
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Entamoeba histolytica tyrosine kinase, putative 0.0956 0.1674 0.2608
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0956 0.1674 0.189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0206 0.0318 0.0478
Entamoeba histolytica hypothetical protein 0.0956 0.1674 0.2608
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0956 0.1674 0.2622
Echinococcus granulosus protein tyrosine kinase 0.0956 0.1674 0.1674
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Entamoeba histolytica protein kinase domain containing protein 0.0956 0.1674 0.2608
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0083 0.0097 0.0097
Loa Loa (eye worm) TK/EGFR protein kinase 0.1107 0.1946 0.2197
Plasmodium falciparum importin beta, putative 0.003 0 0.0003
Loa Loa (eye worm) TK/RYK protein kinase 0.0956 0.1674 0.189
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1674 0.189
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis integrin linked protein kinase 0.0956 0.1674 0.1674
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0269 0.0432 0.0656
Schistosoma mansoni tyrosine kinase 0.0956 0.1674 0.1674
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0024 0.0024
Plasmodium falciparum tyrosine kinase-like protein 0.0956 0.1674 1
Echinococcus multilocularis activated cdc42 kinase 1 0.0956 0.1674 0.1674
Schistosoma mansoni neuropeptide receptor 0.0075 0.0082 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Echinococcus multilocularis expressed protein 0.0379 0.0631 0.0631
Echinococcus granulosus cpg binding protein 0.0062 0.0059 0.0059
Loa Loa (eye worm) TK/FER protein kinase 0.2385 0.4254 0.4804
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082
Brugia malayi GnHR receptor homolog 0.0075 0.0082 0.0129
Echinococcus multilocularis tyrosine protein kinase Src64B 0.2385 0.4254 0.4254
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0209 0.0325 0.0508
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1428 0.2527 0.2527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0234 0.0369 0.0557
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.2593 0.4631 0.7248
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.2385 0.4254 0.4254
Loa Loa (eye worm) hypothetical protein 0.1428 0.2527 0.2853
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0017 0.0027
Echinococcus granulosus tyrosine protein kinase Blk 0.2385 0.4254 0.4254
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0053 0.0043 0.0045
Loa Loa (eye worm) hypothetical protein 0.2385 0.4254 0.4804
Echinococcus granulosus activin receptor type 0.0956 0.1674 0.1674
Echinococcus multilocularis protoporphyrinogen oxidase 0.0043 0.0024 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0083 0.0097 0.0109
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Schistosoma mansoni phosphatidylinositol 4-kinase 0.064 0.1103 0.1103
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0053 0.0043 0.0067
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0059 0.0433
Entamoeba histolytica protein kinase, putative 0.0956 0.1674 0.2608
Echinococcus granulosus NCK adaptor protein 0.1428 0.2527 0.2527
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0178 0.0268 0.042
Echinococcus granulosus SH2 motif 0.1428 0.2527 0.2527
Entamoeba histolytica protein kinase rad3, putative 0.0158 0.0232 0.0345
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0067 0.0076
Brugia malayi Carboxylesterase family protein 0.0084 0.0098 0.0153
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.064 0.1103 0.1245
Echinococcus multilocularis tyrosine protein kinase csk 0.0956 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.0956 0.1674 0.2606
Brugia malayi larval opioid receptor 0.0075 0.0082 0.0129
Brugia malayi Protein kinase domain containing protein 0.0956 0.1674 0.2622
Schistosoma mansoni immunophilin 0.0053 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0063
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0093
Echinococcus granulosus neuropeptide s receptor 0.0075 0.0082 0.0082
Echinococcus granulosus para nitrobenzyl esterase 0.0084 0.0098 0.0098
Loa Loa (eye worm) TYRA-2 protein 0.0075 0.0082 0.0093
Echinococcus granulosus serine protein kinase ATM 0.0158 0.0232 0.0232
Leishmania major phosphatidylinositol kinase, putative 0.0141 0.0202 0.1204
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0082 0.0082

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) Activation of NRF2 in human HaCaT cells expressing rat NQO1 assessed as induction of NQO1 expression at 50 nM to 5 uM incubated for 24 hrs by ARE-driven luciferase reporter gene assay ChEMBL. 25299679
Activity (ADMET) = 90 % Cytotoxicity against human MRC5 cells assessed as cell viability at 10 uM after 48 hrs by inverted microscopy ChEMBL. 25299679
IC50 (ADMET) = 17.44 uM Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 48 hrs by MTT assay ChEMBL. 25299679

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 25299679

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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