Detailed information for compound 954231

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 228.286 | Formula: C15H16O2
  • H donors: 1 H acceptors: 1 LogP: 3.75 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1O)CCc1ccccc1
  • InChi: 1S/C15H16O2/c1-17-15-10-9-13(11-14(15)16)8-7-12-5-3-2-4-6-12/h2-6,9-11,16H,7-8H2,1H3
  • InChiKey: MFBFJSQTXYOUAV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) bromodomain containing protein 0.0037 0.0106 0.028
Trichomonas vaginalis beta-mannosidase, putative 0.0084 0.0652 0.2046
Mycobacterium ulcerans hypothetical protein 0.0077 0.0564 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.0541 0.0541
Loa Loa (eye worm) PHD-finger family protein 0.0043 0.0177 0.0466
Echinococcus granulosus GPCR family 2 0.0032 0.0052 0.0052
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0091 0.0091
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.1365 0.1365
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0038 0.0126 0.1147
Loa Loa (eye worm) hypothetical protein 0.0089 0.0701 0.185
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0042 0.017 0.017
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0038 0.0126 0.0126
Echinococcus granulosus snurportin 1 0.0358 0.3787 0.3787
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0134 0.0134
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0138 0.1727
Loa Loa (eye worm) hypothetical protein 0.0258 0.2637 0.6965
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.017 0.2348
Brugia malayi beta-lactamase family protein 0.0077 0.0564 0.2139
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0564 0.0915
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0564 0.17
Schistosoma mansoni bromodomain containing protein 0.0131 0.1192 0.1192
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0052 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Echinococcus granulosus zinc finger protein 0.0041 0.0151 0.0151
Echinococcus granulosus importin subunit beta 1 0.0034 0.0069 0.0069
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0264 0.0264
Mycobacterium tuberculosis Conserved protein 0.0077 0.0564 0.0915
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.1365 0.1365
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0564 1
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0138 0.0018
Loa Loa (eye worm) hypothetical protein 0.0258 0.2637 0.6965
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0047 0.0222 0.0222
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.017 0.0646
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0564 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0077 0.0564 0.149
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0564 0.17
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0264 0.0264
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0134 0.1303
Trypanosoma brucei DNA polymerase eta, putative 0.0042 0.017 0.2766
Loa Loa (eye worm) hypothetical protein 0.0077 0.0564 0.149
Schistosoma mansoni DNA polymerase eta 0.0042 0.017 0.017
Schistosoma mansoni hypothetical protein 0.0032 0.0052 0.0052
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0091 0.0091
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0134 0.0134
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.017 0.0847
Entamoeba histolytica beta-galactosidase, putative 0.0176 0.1699 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0564 0.149
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0134 0.2096
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0564 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0655 0.173
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.017 0.0144
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.017 0.2348
Brugia malayi PHD-finger family protein 0.0052 0.0278 0.1056
Brugia malayi beta-lactamase family protein 0.0077 0.0564 0.2139
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0138 1
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0564 1
Echinococcus granulosus sodium:glucose cotransporter 2 0.0038 0.0126 0.0126
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0564 0.149
Echinococcus granulosus solute carrier family 5 0.0038 0.0126 0.0126
Brugia malayi mbt repeat family protein 0.0051 0.0264 0.1002
Loa Loa (eye worm) hypothetical protein 0.0058 0.0344 0.091
Echinococcus multilocularis dna polymerase kappa 0.0042 0.017 0.017
Echinococcus multilocularis GPCR, family 2 0.0032 0.0052 0.0052
Schistosoma mansoni inositol transporter 0.0038 0.0126 0.0126
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0138 0.2179
Schistosoma mansoni hypothetical protein 0.0032 0.005 0.005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0138 0.1727
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0035 0.0091 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Loa Loa (eye worm) hypothetical protein 0.0157 0.148 0.391
Loa Loa (eye worm) hypothetical protein 0.0032 0.0052 0.0136
Loa Loa (eye worm) hypothetical protein 0.0077 0.0564 0.149
Schistosoma mansoni hypothetical protein 0.0032 0.0052 0.0052
Trypanosoma brucei unspecified product 0.0042 0.017 0.2766
Leishmania major hypothetical protein, conserved 0.0077 0.0564 1
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.1044 0.2757
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.1365 0.1365
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0236 0.2388 0.6307
Schistosoma mansoni hypothetical protein 0.09 1 1
Loa Loa (eye worm) hypothetical protein 0.0147 0.1369 0.3616
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Schistosoma mansoni sodium/solute symporter 0.0038 0.0126 0.0126
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0564 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.1365 0.1365
Mycobacterium tuberculosis Possible penicillin-binding protein 0.049 0.5301 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.1044 0.2757
Onchocerca volvulus Huntingtin homolog 0.0258 0.2637 1
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.017 0.2766
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0091 0.0091
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0358 0.3787 1
Toxoplasma gondii ABC1 family protein 0.0077 0.0564 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0051 0.0264 0.0698
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0134 0.164
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0826 0.9149 0.9149
Onchocerca volvulus 0.0077 0.0564 0.2139
Trypanosoma brucei ISWI complex protein 0.0032 0.005 0.0546
Schistosoma mansoni hypothetical protein 0.09 1 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0069 0.0912
Echinococcus multilocularis snurportin 1 0.0358 0.3787 0.3787
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0052 0.0136
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.1365 0.1365
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0564 0.0915
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0183
Echinococcus granulosus sodium:glucose cotransporter 0.0038 0.0126 0.0126
Toxoplasma gondii exonuclease III APE 0.004 0.0138 0.1394
Mycobacterium tuberculosis Conserved protein 0.0077 0.0564 0.0915
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0147 0.1365 0.3604
Giardia lamblia DINP protein human, muc B family 0.0042 0.017 1
Echinococcus granulosus sodium:myo inositol cotransporter 0.0038 0.0126 0.0126
Leishmania major DNA polymerase eta, putative 0.0042 0.017 0.2348
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0134 0.164
Brugia malayi Beta-glucuronidase precursor 0.0241 0.2447 0.9279
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0124 0.1107 0.1107
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0564 0.0915
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0147 0.1365 0.5174
Loa Loa (eye worm) hypothetical protein 0.008 0.0599 0.1581
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0042 0.017 0.045
Echinococcus granulosus high affinity choline transporter 1 0.0038 0.0126 0.0126
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0248 0.2528 0.9584
Schistosoma mansoni zinc finger protein 0.0032 0.005 0.005
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0843 0.3197
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.017 0.016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0564 0.0564
Brugia malayi Bromodomain containing protein 0.008 0.0597 0.2264
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0564 0.0564
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0564 0.0564
Brugia malayi mbt repeat family protein 0.0051 0.0264 0.1002
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.017 0.0144
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0358 0.3787 0.3787
Brugia malayi Sodium:solute symporter family protein 0.0038 0.0126 0.0479
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0138 0.0029
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0138 0.0525
Loa Loa (eye worm) hypothetical protein 0.0101 0.0843 0.2227
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0564 0.17
Echinococcus multilocularis solute carrier family 5 0.0038 0.0126 0.0126
Brugia malayi Inositol-1 0.0039 0.0134 0.0508
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.017 0.2348
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.017 0.0847
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0052 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0564 1
Schistosoma mansoni high-affinity choline transporter 0.0038 0.0126 0.0126
Brugia malayi beta-lactamase 0.0077 0.0564 0.2139
Echinococcus multilocularis dna polymerase eta 0.0042 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0042 0.017 0.045
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0077 0.0564 0.149
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0564 0.2139
Brugia malayi Importin beta-1 subunit 0.0034 0.0069 0.0263
Trichomonas vaginalis esterase, putative 0.0077 0.0564 0.17
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0038 0.0126 0.0126
Schistosoma mansoni hypothetical protein 0.0043 0.0177 0.0177
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0052 0.0196
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0042 0.017 0.017
Brugia malayi Bromodomain containing protein 0.0156 0.1471 0.5578
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0138 0.0366
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.0541 0.0541
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0344 0.1306
Brugia malayi RNA, U transporter 1 0.0095 0.0778 0.2949
Mycobacterium ulcerans beta-lactamase 0.0077 0.0564 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Schistosoma mansoni importin beta-1 0.0034 0.0069 0.0069
Schistosoma mansoni beta-mannosidase 0.0084 0.0652 0.0652
Schistosoma mansoni hypothetical protein 0.0032 0.0052 0.0052
Onchocerca volvulus 0.0077 0.0564 0.2139
Trichomonas vaginalis glycoside hydrolase, putative 0.026 0.2666 1
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0138 0.0018
Entamoeba histolytica deoxycytidyl transferase, putative 0.0042 0.017 0.0233
Mycobacterium leprae Probable lipase LipE 0.0077 0.0564 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0207 0.2058 0.2058
Brugia malayi hypothetical protein 0.0258 0.2637 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0564 0.0915
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.1365 0.1365
Schistosoma mansoni hypothetical protein 0.0069 0.0477 0.0477
Brugia malayi manba-prov protein 0.0084 0.0652 0.2472
Schistosoma mansoni ap endonuclease 0.004 0.0138 0.0138
Echinococcus granulosus dna polymerase kappa 0.0042 0.017 0.017
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0042 0.017 0.017
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0069 0.0912
Schistosoma mansoni ap endonuclease 0.004 0.0138 0.0138
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0477 0.1808
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.017 0.2348
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.1365 0.1365
Loa Loa (eye worm) hypothetical protein 0.0069 0.0477 0.1259
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0264 0.0264
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0091 0.0091
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0052 0.0052
Trichomonas vaginalis beta-galactosidase, putative 0.026 0.2666 1
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0264 0.0698
Schistosoma mansoni zinc finger protein 0.0041 0.0151 0.0151
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0344 0.0344
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0124 0.1107 0.1107
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.017 0.2766
Schistosoma mansoni terminal deoxycytidyl transferase 0.0042 0.017 0.017
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0264 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.026 0.2666 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0138 0.1727
Loa Loa (eye worm) MBCTL1 0.0058 0.0344 0.091
Echinococcus multilocularis zinc finger protein 0.0041 0.0151 0.0151
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0138 1
Loa Loa (eye worm) inositol-1 0.0039 0.0134 0.0354
Mycobacterium tuberculosis Conserved protein 0.0077 0.0564 0.0915
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0207 0.2058 0.2058
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0138 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.017 0.2348
Schistosoma mansoni hypothetical protein 0.0091 0.0732 0.0732
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0134 0.164
Onchocerca volvulus Huntingtin homolog 0.0258 0.2637 1
Schistosoma mansoni hypothetical protein 0.0315 0.3297 0.3297
Schistosoma mansoni inositol transporter 0.0038 0.0126 0.0126
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0138 0.0138
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0047 0.0222 0.0222
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0264 0.0264
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0843 0.2227
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0248 0.2528 0.6675
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0052 0.0052
Echinococcus multilocularis importin subunit beta 1 0.0034 0.0069 0.0069
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0564 1
Mycobacterium ulcerans lipase LipD 0.0077 0.0564 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.017 0.016
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0564 0.0564
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0564 0.17
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0564 0.0915
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0138 0.1394
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0038 0.0126 0.0126
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0344 0.0344
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0344 0.0344
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.017 0.2348
Echinococcus granulosus dna polymerase eta 0.0042 0.017 0.017
Schistosoma mansoni inositol monophosphatase 0.0039 0.0134 0.0134
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0264 0.0264
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0264 0.0264
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0138 0.0105
Onchocerca volvulus 0.0038 0.0126 0.0479
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.017 0.2766
Onchocerca volvulus 0.0051 0.0264 0.1002
Echinococcus multilocularis high affinity choline transporter 1 0.0038 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0077 0.0564 0.149
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0564 0.0915
Loa Loa (eye worm) hypothetical protein 0.0038 0.0126 0.0333
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0138 0.5
Loa Loa (eye worm) beta-lactamase 0.0077 0.0564 0.149
Brugia malayi MH2 domain containing protein 0.0119 0.1044 0.3958
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0564 0.17
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0344 0.0344
Brugia malayi GH02984p 0.0038 0.0126 0.0479
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0344 0.0344
Loa Loa (eye worm) beta-glucuronidase 0.0241 0.2447 0.6462
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0052 0.0196
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0038 0.0126 0.0126
Echinococcus multilocularis geminin 0.09 1 1
Leishmania major DNA polymerase kappa, putative 0.0042 0.017 0.2348
Schistosoma mansoni hypothetical protein 0.0032 0.0052 0.0052
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0843 0.3197
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0564 0.0915
Brugia malayi follicle stimulating hormone receptor 0.0236 0.2388 0.9056
Loa Loa (eye worm) hypothetical protein 0.0038 0.0126 0.0333
Schistosoma mansoni inositol monophosphatase 0.0039 0.0134 0.0134
Onchocerca volvulus 0.0077 0.0564 0.2139
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.017 0.0646
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.017 0.2766
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0264 0.1002
Echinococcus granulosus fetal alzheimer antigen falz 0.0047 0.0222 0.0222

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) Binding affinity to bovine brain calmodulin by electrophoretic mobility assay in presence of calcium chloride ChEMBL. 14987052

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.