Detailed information for compound 958268

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 687.87 | Formula: C35H57N7O7
  • H donors: 5 H acceptors: 7 LogP: 3.59 Rotable bonds: 21
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCC(C(=O)C(=O)NCC=C)NC(=O)[C@H]1N(C[C@H]2[C@@H]1C2(C)C)C(=O)[C@H](C(C)(C)C)NC(=O)N[C@H](C(C)(C)C)CN1C(=O)CCNC1=O
  • InChi: 1S/C35H57N7O7/c1-11-13-14-21(26(44)29(46)36-16-12-2)38-28(45)25-24-20(35(24,9)10)18-42(25)30(47)27(34(6,7)8)40-31(48)39-22(33(3,4)5)19-41-23(43)15-17-37-32(41)49/h12,20-22,24-25,27H,2,11,13-19H2,1,3-10H3,(H,36,46)(H,37,49)(H,38,45)(H2,39,40,48)/t20-,21?,22-,24-,25-,27+/m0/s1
  • InChiKey: CMFGRRRIEZPJSG-FTNBAEQSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) latrophilin receptor protein 2 0.0023 0.0053 0.0059
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0109 0.03 0.0335
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0835 0.2385 0.2379
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0152 0.0143
Plasmodium vivax protein kinase Crk2 0.0024 0.0056 0.011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0449 0.1277 0.1425
Schistosoma mansoni ap endonuclease 0.0021 0.0046 0.0051
Giardia lamblia Cathepsin B precursor 0.0386 0.1095 0.2128
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.005
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0125 0.0139
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0386 0.1095 0.2546
Loa Loa (eye worm) AGC/NDR protein kinase 0.0006 0.0004 0.0004
Plasmodium vivax vivapain-2 0.1494 0.4277 1
Schistosoma mansoni cathepsin F (C01 family) 0.1494 0.4277 0.4776
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0024 0.0056 0.0062
Brugia malayi Cathepsin L-like precursor 0.1494 0.4277 0.4776
Echinococcus multilocularis enteropeptidase 0.0006 0.0004 0.0004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1494 0.4277 0.4776
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0014 0.0015
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0046 0.5
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0005 0.0001 0.0002
Toxoplasma gondii cathepsin CPC1 0.0386 0.1095 0.2193
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0005 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1045 0.2987 0.5992
Toxoplasma gondii LsmAD domain-containing protein 0.0012 0.0022 0.0037
Trypanosoma brucei wee1-like protein kinase 0.0038 0.0095 0.0092
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0004
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0058 0.0152 0.0149
Entamoeba histolytica cysteine protease, putative 0.0386 0.1095 0.2555
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0058 0.0152 0.017
Leishmania major cysteine peptidase A (CPA) 0.1494 0.4277 0.4272
Loa Loa (eye worm) hypothetical protein 0.0386 0.1095 0.1223
Giardia lamblia Cysteine protease 0.0386 0.1095 0.2128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Onchocerca volvulus 0.0006 0.0004 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0045 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0386 0.1095 0.2193
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0056 0.0062
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0222 0.0625 0.0698
Trypanosoma cruzi major cysteine proteinase, putative 0.2379 0.6818 0.6815
Trypanosoma cruzi cruzipain precursor, putative 0.0449 0.1277 0.1269
Echinococcus multilocularis cathepsin L cysteine protease 0.1494 0.4277 0.4776
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0386 0.1095 0.2546
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.174 0.4983 0.4979
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.002 0.0045 0.0096
Loa Loa (eye worm) cysteine protease 0.1494 0.4277 0.4776
Loa Loa (eye worm) isocitrate dehydrogenase 0.0008 0.0009 0.001
Echinococcus multilocularis transmembrane protease serine 3 0.0006 0.0004 0.0004
Brugia malayi Trypsin family protein 0.0006 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0386 0.1095 0.2193
Plasmodium vivax serine-repeat antigen (SERA) 0.0386 0.1095 0.2546
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0006 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0008 0.0009 0.0005
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Giardia lamblia Cathepsin B precursor 0.0386 0.1095 0.2128
Echinococcus multilocularis cyclin dependent kinase 0.0024 0.0056 0.0062
Plasmodium falciparum cysteine repeat modular protein 1 0.0042 0.0108 0.0232
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0386 0.1095 0.2546
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0222 0.0625 0.0698
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0151 0.0296
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1494 0.4277 0.8583
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0036
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0045 0.0036
Schistosoma mansoni cpg binding protein 0.0032 0.0078 0.0088
Plasmodium vivax vivapain-2 0.1494 0.4277 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0008 0.0009 0.001
Echinococcus granulosus protein kinase c iota type 0.0053 0.0138 0.0154
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0008 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1494 0.4277 0.8583
Echinococcus granulosus protein kinase c epsilon type 0.0009 0.0013 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1494 0.4277 0.8583
Toxoplasma gondii hypoxia- inducible factor prolyl hydroxylase (phd2), putative 0.0008 0.0009 0.0011
Trypanosoma cruzi cdc2-related kinase 1 0.0024 0.0056 0.0047
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0449 0.1277 0.1425
Onchocerca volvulus 0.0006 0.0004 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0386 0.1095 0.2193
Plasmodium vivax vivapain-3 0.0835 0.2385 0.5568
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0149 0.0146
Schistosoma mansoni hypothetical protein 0.0023 0.0053 0.0059
Brugia malayi nuclear hormone receptor 0.0005 0.0001 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0835 0.2385 0.2379
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0835 0.2385 0.2663
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0006 0.0004 0.0004
Onchocerca volvulus 0.0042 0.0108 0.0252
Plasmodium vivax ataxin-2 like protein, putative 0.0012 0.0022 0.0031
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0386 0.1095 0.2128
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0024 0.0056 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0001 0.0002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0046 0.0037
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0005 0.0001 0.0002
Entamoeba histolytica cysteine protease, putative 0.0386 0.1095 0.2555
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0046 0.0037
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.3486 1 1
Loa Loa (eye worm) hypothetical protein 0.1045 0.2987 0.3335
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1494 0.4277 0.8583
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0149 0.0167
Onchocerca volvulus Bile acid receptor homolog 0.0005 0.0001 0.0003
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0045 0.005
Echinococcus multilocularis cathepsin L 0.0835 0.2385 0.2663
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0046 0.0051
Giardia lamblia Cysteine protease 0.0386 0.1095 0.2128
Loa Loa (eye worm) fibroinase 0.1494 0.4277 0.4776
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1494 0.4277 0.8583
Brugia malayi CXXC zinc finger family protein 0.003 0.0073 0.0082
Trypanosoma cruzi cysteine peptidase, putative 0.1494 0.4277 0.4272
Brugia malayi Papain family cysteine protease containing protein 0.1494 0.4277 0.4776
Echinococcus multilocularis cathepsin L cysteine protease 0.1494 0.4277 0.4776
Echinococcus multilocularis neuropeptide s receptor 0.0487 0.1384 0.1546
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0386 0.1095 0.2546
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.002 0.0045 0.9717
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0028 0.0067 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0108 0.0099
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.174 0.4983 0.5564
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0386 0.1095 0.2193
Schistosoma mansoni cathepsin S (C01 family) 0.0386 0.1095 0.1223
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1494 0.4277 0.8583
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0006
Echinococcus granulosus cathepsin l1 0.1494 0.4277 0.4776
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0005 0.0001 0.0002
Trypanosoma cruzi lanosterol synthase, putative 0.002 0.0045 0.0036
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Toxoplasma gondii cathepsin CPL 0.1494 0.4277 0.8583
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0006 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0008 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0002
Entamoeba histolytica cysteine protease, putative 0.1494 0.4277 1
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0052 0.0135 0.0151
Echinococcus multilocularis serine:threonine protein kinase 38 0.0006 0.0004 0.0004
Brugia malayi cell division control protein 2 homolog 0.0024 0.0056 0.0062
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0006 0.0003 0.0003
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0046 0.5
Schistosoma mansoni hypothetical protein 0.0006 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0001 0.0002
Toxoplasma gondii cathepsin CPC2 0.0386 0.1095 0.2193
Echinococcus multilocularis hypothetical protein 0.0006 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0386 0.1095 0.2193
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0386 0.1095 0.2555
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0006
Toxoplasma gondii hypothetical protein 0.0165 0.0459 0.0915
Brugia malayi Trypsin family protein 0.0006 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0006
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0045 0.0084
Echinococcus granulosus plexin a4 0.0016 0.0033 0.0037
Brugia malayi Papain family cysteine protease containing protein 0.0835 0.2385 0.2663
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1494 0.4277 0.8583
Brugia malayi Cathepsin L-like precursor 0.1494 0.4277 0.4776
Onchocerca volvulus Protein ultraspiracle homolog 0.0005 0.0001 0.0003
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0386 0.1095 0.2546
Trypanosoma cruzi cysteine peptidase, putative 0.3486 1 1
Schistosoma mansoni hypothetical protein 0.043 0.1223 0.1366
Brugia malayi steroid hormone receptor 0.0005 0.0001 0.0002
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0038 0.0095 0.0087
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0386 0.1095 0.2555
Brugia malayi Protein kinase domain containing protein 0.0006 0.0004 0.0004
Trypanosoma cruzi cysteine protease, putative 0.0835 0.2385 0.2379
Echinococcus granulosus serine:threonine protein kinase N2 0.0006 0.0004 0.0004
Giardia lamblia Cathepsin L precursor 0.0386 0.1095 0.2128
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0024 0.0056 0.0062
Echinococcus multilocularis cyclin dependent kinase 1 0.0024 0.0056 0.0062
Echinococcus multilocularis cyclin dependent kinase 5 0.0024 0.0056 0.0062
Plasmodium falciparum cysteine proteinase falcipain 3 0.1494 0.4277 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1494 0.4277 0.8583
Brugia malayi hypothetical protein 0.0012 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0138 0.0382 0.0427
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0386 0.1095 0.1223
Onchocerca volvulus 0.0014 0.0026 0.0061
Plasmodium falciparum ataxin-2 like protein, putative 0.0012 0.0022 0.0031
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0058 0.0152 0.0149
Echinococcus multilocularis cysteine protease 0.1494 0.4277 0.4776
Schistosoma mansoni serine/threonine protein kinase 0.0006 0.0004 0.0004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0449 0.1277 0.1425
Onchocerca volvulus 0.0008 0.0009 0.0021
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0045 0.0082
Brugia malayi hypothetical protein 0.0006 0.0003 0.0003
Trypanosoma cruzi lanosterol synthase, putative 0.002 0.0045 0.0036
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0008 0.0009
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0005 0.0001 0.0002
Brugia malayi Cathepsin L-like precursor 0.1494 0.4277 0.4776
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0835 0.2385 0.2663
Brugia malayi Papain family cysteine protease containing protein 0.0386 0.1095 0.1223
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.3123 0.8957 1
Plasmodium falciparum geranylgeranyltransferase, putative 0.002 0.0045 0.0084
Toxoplasma gondii preprocathepsin c precursor, putative 0.0386 0.1095 0.2193
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0004
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0046 0.0037
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0045 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0386 0.1095 0.2193
Trypanosoma brucei lanosterol synthase 0.002 0.0045 0.0041
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0149 0.0167
Echinococcus multilocularis plexin a4 0.0016 0.0033 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Giardia lamblia Cathepsin L-like protease 0.0386 0.1095 0.2128
Giardia lamblia Rab geranylgeranyltransferase 0.0222 0.0625 0.1175
Leishmania major cathepsin L-like protease 0.1494 0.4277 0.4272
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Brugia malayi MAP kinase sur-1 0.0057 0.0149 0.0167
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0024 0.0056 0.0047
Schistosoma mansoni plexin 0.0008 0.001 0.0011
Schistosoma mansoni hypothetical protein 0.0023 0.0053 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0149 0.0292
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0058 0.0152 0.0348
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0386 0.1095 0.2193
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0046 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0006
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0386 0.1095 0.1223
Schistosoma mansoni cathepsin F (C01 family) 0.1045 0.2987 0.3335
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0005 0.0001 0.0002
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1494 0.4277 0.4776
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0386 0.1095 0.1223
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Toxoplasma gondii isocitrate dehydrogenase 0.0008 0.0009 0.0011
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0006 0.0004 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0125 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0005 0.0001 0.0002
Trypanosoma cruzi cdc2-related kinase 1 0.0024 0.0056 0.0047
Giardia lamblia Cathepsin B precursor 0.0386 0.1095 0.2128
Echinococcus granulosus cathepsin L cysteine proteinase 0.1494 0.4277 0.4776
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0005 0.0001 0.0002
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0005 0.0001 0.0002
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.174 0.4983 0.4979
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Brugia malayi Trypsin family protein 0.0006 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1494 0.4277 0.8583
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0073 0.0082
Onchocerca volvulus 0.1494 0.4277 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0125 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0386 0.1095 0.2193
Onchocerca volvulus 0.0006 0.0004 0.0008
Trypanosoma brucei cysteine peptidase C (CPC) 0.174 0.4983 0.4981
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0149 0.014
Brugia malayi p70 ribosomal S6 kinase beta 0.0006 0.0004 0.0004
Brugia malayi Cathepsin L-like precursor 0.1045 0.2987 0.3335
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3123 0.8957 1
Schistosoma mansoni cathepsin B (C01 family) 0.0386 0.1095 0.1223
Entamoeba histolytica cell division protein kinase 2, putative 0.0024 0.0056 0.0122
Schistosoma mansoni hypothetical protein 0.005 0.013 0.0145
Echinococcus granulosus glycoprotein Antigen 5 0.0006 0.0004 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0005 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2385 0.4783
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0005 0.0001 0.0002
Entamoeba histolytica cysteine protease, putative 0.0386 0.1095 0.2555
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0005 0.0001 0.0002
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Echinococcus multilocularis geminin 0.0185 0.0518 0.0578
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0222 0.0625 0.1248
Trichomonas vaginalis helicase, putative 0.0007 0.0006 0.0006
Schistosoma mansoni ap endonuclease 0.0021 0.0046 0.0051
Schistosoma mansoni semaphorin 5-related 0.0006 0.0003 0.0003
Onchocerca volvulus 0.1494 0.4277 1
Plasmodium falciparum protein kinase 5 0.0024 0.0056 0.011
Entamoeba histolytica cysteine proteinase, putative 0.1494 0.4277 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0449 0.1277 0.1425
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.174 0.4983 1
Loa Loa (eye worm) plexin A 0.0016 0.0033 0.0037
Loa Loa (eye worm) hypothetical protein 0.0386 0.1095 0.1223
Loa Loa (eye worm) AGC/PKN protein kinase 0.0006 0.0004 0.0004
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0024 0.0056 0.0062
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0222 0.0625 0.0698
Entamoeba histolytica cysteine proteinase, putative 0.0835 0.2385 0.5573
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0005 0.0001 0.0002
Schistosoma mansoni cpg binding protein 0.003 0.0073 0.0082
Plasmodium falciparum cysteine proteinase falcipain 1 0.0835 0.2385 0.5568
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.002 0.0045 0.005
Schistosoma mansoni thyroid hormone receptor 0.0005 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0067 0.0075
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0386 0.1095 0.1223
Onchocerca volvulus 0.0005 0.0001 0.0003
Loa Loa (eye worm) ctsf protein 0.1494 0.4277 0.4776
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0008 0.0009
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3123 0.8957 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0006 0.0004 0.0004
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0024 0.0056 0.0062
Plasmodium vivax serine-repeat antigen (SERA) 0.0386 0.1095 0.2546
Brugia malayi Cathepsin L-like cysteine proteinase 0.1045 0.2987 0.3335
Entamoeba histolytica cysteine protease, putative 0.0386 0.1095 0.2555
Brugia malayi Steroid receptor seven-up type 2 0.0005 0.0001 0.0002
Leishmania major cathepsin L-like protease 0.3486 1 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3123 0.8957 0.8956
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0222 0.0625 0.1454
Echinococcus granulosus cyclin dependent kinase 0.0024 0.0056 0.0062
Plasmodium falciparum serine repeat antigen 9 0.0386 0.1095 0.2546
Giardia lamblia Cathepsin B precursor 0.174 0.4983 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0006 0.0004 0.0004
Brugia malayi Cathepsin L-like precursor 0.0449 0.1277 0.1425
Onchocerca volvulus 0.1045 0.2987 0.6984
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Echinococcus multilocularis semaphorin 5B 0.0006 0.0003 0.0003
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0222 0.0625 0.1248
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0005 0.0001 0.0002
Leishmania major hypothetical protein, conserved 0.0012 0.0022 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0045 0.0082
Plasmodium falciparum serine repeat antigen 1 0.0386 0.1095 0.2546
Entamoeba histolytica cysteine proteinase 1, putative 0.0835 0.2385 0.5573
Loa Loa (eye worm) hypothetical protein 0.0042 0.0108 0.0121
Trypanosoma brucei hypothetical protein, conserved 0.0058 0.0152 0.0149
Plasmodium falciparum serine repeat antigen 6 0.0386 0.1095 0.2546
Echinococcus multilocularis glycoprotein Antigen 5 0.0006 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2385 0.4783
Trypanosoma brucei cdc2-related kinase 1 0.0024 0.0056 0.0052
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0058 0.0152 0.0335
Brugia malayi cathepsin Z-like cysteine proteinase 0.0386 0.1095 0.1223
Brugia malayi latrophilin 2 splice variant baaae 0.005 0.013 0.0145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0125 0.0139
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0014 0.0015
Echinococcus granulosus cathepsin l cysteine peptidase 0.1494 0.4277 0.4776
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0149 0.0292
Brugia malayi protein kinase C3,putative 0.0048 0.0126 0.014
Schistosoma mansoni serine/threonine kinase 0.0006 0.0004 0.0004
Brugia malayi cathepsin B-like cysteine proteinase 0.3123 0.8957 1
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0045 0.0084
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0386 0.1095 0.2546
Toxoplasma gondii kringle domain-containing protein 0.0042 0.0108 0.021
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1494 0.4277 0.8583
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0006 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0009 0.0013 0.0014
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0149 0.0167
Entamoeba histolytica cysteine proteinase, putative 0.0835 0.2385 0.5573
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0005 0.0001 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.043 0.1223 0.1366
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0023 0.0053 0.0059
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Onchocerca volvulus 0.0006 0.0004 0.0008
Brugia malayi cathepsin L-like precursor 0.1045 0.2987 0.3335
Schistosoma mansoni retinoic acid receptor RXR 0.0005 0.0001 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0386 0.1095 0.1223
Brugia malayi hypothetical protein 0.0006 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Onchocerca volvulus Cathepsin L homolog 0.1494 0.4277 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Echinococcus granulosus NDR protein kinase 0.0006 0.0004 0.0004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0001 0.0002
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0058 0.0152 0.0298
Leishmania major cathepsin L-like protease 0.3486 1 1
Plasmodium vivax unspecified product 0.0449 0.1277 0.297
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0006 0.0004 0.0004
Onchocerca volvulus 0.003 0.0073 0.0172
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0046 0.0051
Trypanosoma cruzi Wee1-like protein kinase, putative 0.0038 0.0095 0.0087
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0149 0.0292
Schistosoma mansoni metabotropic glutamate receptor 0.0019 0.0041 0.0046
Trypanosoma cruzi cdc2-related kinase 3 0.0024 0.0056 0.0047
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0386 0.1095 0.2128
Echinococcus granulosus cathepsin L 0.0386 0.1095 0.1223
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0045 0.0082
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0005 0.0001 0.0002
Giardia lamblia Encystation-specific protease 0.0386 0.1095 0.2128
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0165 0.0459 0.0915
Brugia malayi Cathepsin L-like precursor 0.1494 0.4277 0.4776
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0006 0.0004 0.0004
Echinococcus granulosus cysteine protease 0.0835 0.2385 0.2663
Giardia lamblia Cathepsin L precursor 0.0386 0.1095 0.2128
Brugia malayi Kringle domain containing protein 0.0042 0.0108 0.0121
Echinococcus multilocularis tissue type plasminogen activator 0.0042 0.0108 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Loa Loa (eye worm) sema domain-containing protein 0.0006 0.0003 0.0003
Schistosoma mansoni cathepsin F (C01 family) 0.1494 0.4277 0.4776
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0005 0.0001 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0149 0.0292
Giardia lamblia Cathepsin B precursor 0.0386 0.1095 0.2128
Echinococcus multilocularis ecdysone induced protein 78C 0.0005 0.0001 0.0002
Toxoplasma gondii exonuclease III APE 0.0021 0.0046 0.0085
Brugia malayi isocitrate dehydrogenase 0.0008 0.0009 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0045 0.0036
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0386 0.1095 0.2546
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0149 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0386 0.1095 0.2193
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0006 0.0003 0.0004
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.002 0.0045 0.005
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0222 0.0625 0.1248
Leishmania major geranylgeranyltransferase, putative 0.002 0.0045 0.0036
Leishmania major cathepsin L-like protease 0.1494 0.4277 0.4272
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0125 0.0139
Trypanosoma brucei protein farnesyltransferase beta subunit 0.002 0.0045 0.0041
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0006 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.03 0.0335
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0006
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0058 0.0152 0.0143
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0006 0.0004 0.0004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1494 0.4277 0.4776
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Plasmodium falciparum ataxin-2 like protein, putative 0.0012 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0386 0.1095 0.1223
Schistosoma mansoni cathepsin C 0.0386 0.1095 0.1223
Giardia lamblia Cathepsin L precursor 0.0386 0.1095 0.2128
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0006 0.0004 0.0004
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0006 0.0004 0.0004
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0386 0.1095 0.1223
Echinococcus granulosus tissue type plasminogen activator 0.0042 0.0108 0.0121
Onchocerca volvulus 0.0006 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.1045 0.2987 0.3335
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Onchocerca volvulus 0.0386 0.1095 0.2561
Schistosoma mansoni hypothetical protein 0.0006 0.0003 0.0003
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0149 0.0167
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0082
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0056 0.0105
Onchocerca volvulus Cathepsin F homolog 0.1494 0.4277 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0008 0.0009 0.001
Echinococcus granulosus FTZ F1 alpha 0.0005 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0023 0.0053 0.0059
Loa Loa (eye worm) cathepsin B 0.174 0.4983 0.5564
Trypanosoma cruzi cysteine peptidase, putative 0.3486 1 1
Loa Loa (eye worm) hypothetical protein 0.005 0.013 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0005 0.0001 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.1045 0.2987 0.6982
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0005 0.0001 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0012 0.0022 0.0013
Brugia malayi Latrophilin receptor protein 2 0.0023 0.0053 0.0059
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0058 0.0152 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0046 0.0051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0386 0.1095 0.2193
Echinococcus granulosus protein farnesyltransferase subunit beta 0.002 0.0045 0.005
Loa Loa (eye worm) hypothetical protein 0.0386 0.1095 0.1223
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0058 0.0152 0.0149
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0386 0.1095 0.1223
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Plasmodium vivax farnesyltransferase beta subunit, putative 0.002 0.0045 0.0084
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0386 0.1095 0.2546
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0005 0.0001 0.0002
Echinococcus granulosus transmembrane protease serine 3 0.0006 0.0004 0.0004
Plasmodium falciparum serine repeat antigen 7 0.0386 0.1095 0.2546
Giardia lamblia Cathepsin B precursor 0.174 0.4983 1
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0386 0.1095 0.2546
Brugia malayi Sema domain containing protein 0.0006 0.0003 0.0003
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0006 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Leishmania major cathepsin L-like protease 0.1494 0.4277 0.4272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Onchocerca volvulus 0.1494 0.4277 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3123 0.8957 1
Echinococcus granulosus semaphorin 1A 0.0006 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0006 0.0004 0.0004
Echinococcus granulosus cathepsin L 0.0835 0.2385 0.2663
Echinococcus multilocularis protein kinase c epsilon type 0.0009 0.0013 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0046 0.0085
Loa Loa (eye worm) hypothetical protein 0.1045 0.2987 0.3335
Toxoplasma gondii isocitrate dehydrogenase 0.0008 0.0009 0.0011
Brugia malayi ecdysteroid receptor 0.0005 0.0001 0.0002
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0006 0.0004 0.0004
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0023 0.0053 0.0059
Brugia malayi Calcitonin receptor-like protein seb-1 0.0073 0.0196 0.0219
Echinococcus granulosus cathepsin b 0.3123 0.8957 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0002
Entamoeba histolytica hypothetical protein 0.0386 0.1095 0.2555
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0005 0.0001 0.0002
Echinococcus granulosus ecdysone induced protein 78C 0.0005 0.0001 0.0002
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0046 0.0002
Giardia lamblia Cathepsin L precursor 0.0386 0.1095 0.2128
Loa Loa (eye worm) glutamate receptor 0.0009 0.0012 0.0014
Brugia malayi Protein kinase domain containing protein 0.0109 0.03 0.0335
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0008 0.0009
Plasmodium vivax unspecified product 0.0386 0.1095 0.2546
Trypanosoma cruzi cruzipain precursor, putative 0.3486 1 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0004
Trypanosoma cruzi Wee1-like protein kinase, putative 0.0038 0.0095 0.0087
Echinococcus granulosus neuropeptide s receptor 0.0487 0.1384 0.1546
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0006 0.0004 0.0004
Schistosoma mansoni protein farnesyltransferase subunit beta 0.002 0.0045 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0386 0.1095 0.2193
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0386 0.1095 0.2193
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0006 0.0004 0.0004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0125 0.0139
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0023 0.0053 0.0059
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0006 0.0004 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0835 0.2385 0.5573
Plasmodium falciparum serine repeat antigen 4 0.0386 0.1095 0.2546
Loa Loa (eye worm) hypothetical protein 0.0073 0.0196 0.0219
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0021 0.0046 0.0051
Plasmodium vivax vivapain-1 0.0835 0.2385 0.5568
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.002 0.0045 0.0096
Brugia malayi cathepsin Z-like cysteine proteinase 0.0386 0.1095 0.1223
Brugia malayi cathepsin F-like cysteine proteinase 0.0386 0.1095 0.1223
Brugia malayi Metabotropic glutamate receptor precursor. 0.0023 0.0052 0.0058
Echinococcus granulosus Mastin 0.0006 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0006 0.0003 0.0003
Onchocerca volvulus 0.1494 0.4277 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0005 0.0001 0.0002
Echinococcus granulosus GPCR family 2 0.0023 0.0053 0.0059
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0005 0.0001 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0012 0.0022 0.0013
Loa Loa (eye worm) hypothetical protein 0.0386 0.1095 0.1223
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0058 0.0152 0.017
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.002 0.0045 0.0082
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0386 0.1095 0.1223
Toxoplasma gondii cathepsin B 0.174 0.4983 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0004
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.002 0.0045 0.005
Echinococcus granulosus cathepsin b 0.3123 0.8957 1
Giardia lamblia Cathepsin L-like protease 0.0386 0.1095 0.2128
Echinococcus granulosus cyclin dependent kinase 1 0.0024 0.0056 0.0062
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Brugia malayi Receptor family ligand binding region containing protein 0.0006 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0449 0.1277 0.1425
Plasmodium falciparum serine repeat antigen 3 0.0386 0.1095 0.2546
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0149 0.0167
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0386 0.1095 0.2193
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0045 0.0082
Echinococcus granulosus metabotropic glutamate receptor 5 0.0028 0.0067 0.0075
Entamoeba histolytica cysteine protease, putative 0.0386 0.1095 0.2555
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1494 0.4277 1
Plasmodium falciparum serine repeat antigen 8 0.0386 0.1095 0.2546
Brugia malayi fibroinase precursor 0.0386 0.1095 0.1223
Leishmania major cathepsin L-like protease 0.1494 0.4277 0.4272
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0149 0.0167
Schistosoma mansoni cathepsin s 0.0449 0.1277 0.1425
Echinococcus multilocularis serine:threonine protein kinase N2 0.0006 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.1494 0.4277 0.4776
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0024 0.0056 0.0105
Brugia malayi Protein kinase domain containing protein 0.0006 0.0004 0.0004
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0149 0.014
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0125 0.0139
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0386 0.1095 0.2193
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0005 0.0000012599 0.0000014066
Trypanosoma brucei 2OG-Fe(II) oxygenase superfamily, putative 0.0008 0.0009 0.0006
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0046 1
Trypanosoma brucei protein kinase, putative 0.0057 0.0149 0.0146
Plasmodium falciparum serine repeat antigen 2 0.0386 0.1095 0.2546
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0386 0.1095 0.2193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0058 0.0152 0.017
Giardia lamblia Cysteine protease 0.0386 0.1095 0.2128
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0008 0.0009 0.0011
Echinococcus granulosus geminin 0.0185 0.0518 0.0578
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Schistosoma mansoni atypical protein kinase C 0.0056 0.0148 0.0165
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0008 0.0009 0.001
Brugia malayi Isocitrate dehydrogenase 0.0008 0.0009 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0056 0.0105
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0133 0.0368 0.0853
Brugia malayi Plexin repeat family protein 0.0014 0.0026 0.0029
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.3037 0.871 0.8709
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0006 0.0006
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0019 0.0041 0.0046
Schistosoma mansoni hypothetical protein 0.0042 0.0108 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.0006 0.0004 0.0004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0386 0.1095 0.1223
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Schistosoma mansoni steroid hormone receptor ad4bp 0.0005 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0149 0.014
Trypanosoma cruzi cysteine proteinase, putative 0.0835 0.2385 0.2379
Echinococcus multilocularis serine:threonine protein kinase N2 0.0006 0.0004 0.0004
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0005 0.0001 0.0002
Toxoplasma gondii tetratricopeptide repeat-containing protein 0.0008 0.0009 0.0011
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0133 0.0368 0.0411
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0006
Brugia malayi Cathepsin L-like precursor 0.1045 0.2987 0.3335
Trichomonas vaginalis conserved hypothetical protein 0.0386 0.1095 0.2193
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0005 0.0001 0.0002
Brugia malayi Trypsin-like protease protein 5 0.0006 0.0004 0.0004
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0386 0.1095 0.2546
Trypanosoma cruzi cysteine peptidase, putative 0.0449 0.1277 0.1269
Trypanosoma cruzi cysteine proteinase, putative 0.0835 0.2385 0.2379
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0133 0.0368 0.0411
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0386 0.1095 0.2546
Echinococcus multilocularis isocitrate dehydrogenase 0.0008 0.0009 0.001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0171 0.0191
Brugia malayi Papain family cysteine protease containing protein 0.0386 0.1095 0.1223
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2385 0.2383
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0008 0.0009 0.001
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0133 0.0368 0.0411
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0386 0.1095 0.2128
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0013 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0006 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0006
Loa Loa (eye worm) TK/ROR protein kinase 0.0043 0.011 0.0123
Loa Loa (eye worm) sema domain-containing protein 0.0006 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Echinococcus granulosus Protein kinase C brain isozyme 0.0009 0.0013 0.0014
Entamoeba histolytica cysteine protease, putative 0.0386 0.1095 0.2555
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0005 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0006
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0386 0.1095 0.1223
Echinococcus granulosus metabotropic glutamate receptor 2 0.0019 0.0041 0.0046
Entamoeba histolytica cysteine proteinase 2 0.0835 0.2385 0.5573
Schistosoma mansoni hypothetical protein 0.0008 0.001 0.0011
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0222 0.0625 0.0698
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0045 0.0082
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3123 0.8957 1
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0008 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0004
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0082
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0004
Echinococcus multilocularis serine threonine protein kinase 0.0006 0.0004 0.0004
Onchocerca volvulus 0.0058 0.0152 0.0356
Giardia lamblia Cathepsin L precursor 0.0386 0.1095 0.2128
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Echinococcus multilocularis neuropeptide receptor A26 0.0487 0.1384 0.1546
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0006 0.0004 0.0004
Onchocerca volvulus 0.0006 0.0003 0.0007
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0041
Schistosoma mansoni hypothetical protein 0.0023 0.0053 0.0059
Brugia malayi nuclear receptor NHR-88 0.0005 0.0001 0.0002
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0133 0.0368 0.0411
Onchocerca volvulus Cathepsin L homolog 0.0386 0.1095 0.2561
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0013 0.0014
Giardia lamblia Cathepsin L precursor 0.0386 0.1095 0.2128
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0058 0.0152 0.017
Schistosoma mansoni metabotropic glutamate receptor 0.0011 0.0019 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0013 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0125 0.0139
Brugia malayi protein kinase C II. 0.0009 0.0013 0.0014
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0005 0.0001 0.0002
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0133 0.0368 0.0732
Trichomonas vaginalis conserved hypothetical protein 0.0386 0.1095 0.2193
Loa Loa (eye worm) hypothetical protein 0.0023 0.0052 0.0058
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0046 0.0085
Echinococcus multilocularis Mastin 0.0006 0.0004 0.0004
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0008 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0222 0.0625 0.0698
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0009 0.0013 0.0014
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0058 0.0152 0.0143
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0058 0.0152 0.017
Echinococcus granulosus cpg binding protein 0.0032 0.0078 0.0088
Echinococcus multilocularis GPCR, family 2 0.0023 0.0053 0.0059
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0046 1
Brugia malayi Protein kinase domain containing protein 0.0005 0.0000012599 0.0000014066
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0222 0.0625 0.1443
Entamoeba histolytica cell division protein kinase 2, putative 0.0024 0.0056 0.0122
Loa Loa (eye worm) hypothetical protein 0.0014 0.0026 0.0029
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0058 0.0152 0.0143
Echinococcus multilocularis cysteine protease 0.1494 0.4277 0.4776
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0006 0.0006
Trypanosoma brucei cdc2-related kinase 3 0.0024 0.0056 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1045 0.2987 0.5992
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0006 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2385 0.2383
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0005 0.0001 0.0003
Echinococcus granulosus dnaJ subfamily B 0.043 0.1223 0.1366
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0002
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0023 0.0053 0.0059
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0133 0.0368 0.0411
Trypanosoma cruzi major cysteine proteinase, putative 0.0386 0.1095 0.1088
Leishmania major cathepsin L-like protease 0.1494 0.4277 0.4272
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0046 0.0051
Brugia malayi Cathepsin L-like precursor 0.1494 0.4277 0.4776
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0046 0.0042
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.002 0.0045 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0152 0.0143
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0006 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Loa Loa (eye worm) AGC/AKT protein kinase 0.0006 0.0004 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0009 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0013 0.0014
Brugia malayi cathepsin L-like cysteine proteinase 0.0386 0.1095 0.1223
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0046 0.0086
Brugia malayi Protein kinase domain containing protein 0.0024 0.0056 0.0062
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0006 0.0004 0.0004
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0023 0.0053 0.0059
Echinococcus granulosus semaphorin 5B 0.0006 0.0003 0.0003
Onchocerca volvulus 0.1494 0.4277 1
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.002 0.0045 0.005
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0008 0.0009 0.001
Brugia malayi prolyl 4-hydroxylase 0.0008 0.0009 0.001
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0386 0.1095 0.1223
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0386 0.1095 0.2546
Echinococcus granulosus cathepsin L cysteine protease 0.0835 0.2385 0.2663
Giardia lamblia Hypothetical protein 0.0386 0.1095 0.2128
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0005 0.0001 0.0002
Trypanosoma cruzi cdc2-related kinase 3 0.0024 0.0056 0.0047
Toxoplasma gondii hypothetical protein 0.0058 0.0152 0.0298
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0006
Loa Loa (eye worm) trypsin family protein 0.0006 0.0004 0.0004
Schistosoma mansoni thyroid hormone receptor 0.0005 0.0001 0.0002
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1494 0.4277 1
Echinococcus multilocularis protein kinase c iota type 0.0053 0.0138 0.0154
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0005 0.0001 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0006 0.0004 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.0005 0.0001 0.0002
Brugia malayi Cathepsin L-like precursor 0.1494 0.4277 0.4776
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1494 0.4277 0.4776
Echinococcus multilocularis cathepsin b 0.3123 0.8957 1
Giardia lamblia Cathepsin B precursor 0.0386 0.1095 0.2128
Trypanosoma brucei PAB1-binding protein , putative 0.0012 0.0022 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0005 0.0001 0.0002
Trypanosoma cruzi Wee1-like protein kinase, putative 0.0038 0.0095 0.0087
Onchocerca volvulus 0.0006 0.0004 0.0008
Brugia malayi photoreceptor-specific nuclear receptor 0.0005 0.0001 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0005 0.0001 0.0002
Echinococcus multilocularis thyroid hormone receptor alpha 0.0005 0.0001 0.0002
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0026 0.0061 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0005 0.0001 0.0002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0386 0.1095 0.1223
Echinococcus multilocularis cathepsin b 0.3123 0.8957 1
Schistosoma mansoni hypothetical protein 0.0185 0.0518 0.0578
Schistosoma mansoni coup transcription factor 0.0005 0.0001 0.0002
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0058 0.0152 0.017
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0005 0.0001 0.0002
Brugia malayi metabotropic glutamate receptor type 2 0.0011 0.0019 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0009 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1494 0.4277 0.8583
Schistosoma mansoni hypothetical protein 0.0006 0.0004 0.0004
Onchocerca volvulus Cathepsin L homolog 0.1494 0.4277 1
Onchocerca volvulus 0.1494 0.4277 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3486 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0056 0.0105
Loa Loa (eye worm) hypothetical protein 0.0386 0.1095 0.1223
Echinococcus granulosus cathepsin l1 0.1045 0.2987 0.3335
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0386 0.1095 0.1223
Loa Loa (eye worm) hypothetical protein 0.0012 0.0022 0.0025
Loa Loa (eye worm) steroid hormone receptor 0.0005 0.0001 0.0002
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0006 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1494 0.4277 0.8583
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0058 0.0152 0.0143
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0014 0.0015
Plasmodium vivax geranylgeranyltransferase, putative 0.002 0.0045 0.0084
Leishmania major hypothetical protein, conserved 0.0042 0.0108 0.0099
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0058 0.0152 0.0335
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0073 0.0196 0.0219
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0082
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0149 0.0292
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0149 0.014
Echinococcus multilocularis cpg binding protein 0.0032 0.0078 0.0088
Echinococcus multilocularis cathepsin L 0.0386 0.1095 0.1223
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0386 0.1095 0.2546
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0149 0.014
Brugia malayi Protein kinase domain containing protein 0.0043 0.011 0.0123
Loa Loa (eye worm) glutamate receptor 0.0023 0.0052 0.0058
Brugia malayi hypothetical protein 0.0006 0.0004 0.0004
Brugia malayi cathepsin F-like cysteine proteinase 0.0449 0.1277 0.1425
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0045 0.005
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0835 0.2385 0.2663
Leishmania major farnesyltransferase beta subunit 0.002 0.0045 0.0036
Echinococcus granulosus neuropeptide receptor A26 0.0487 0.1384 0.1546
Entamoeba histolytica cysteine protease, putative 0.0835 0.2385 0.5573
Schistosoma mansoni hypothetical protein 0.0185 0.0518 0.0578
Giardia lamblia Kinase, CMGC CDK 0.0024 0.0056 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0835 0.2385 0.5573
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0386 0.1095 0.2128
Plasmodium vivax unspecified product 0.0835 0.2385 0.5568
Brugia malayi Sema domain containing protein 0.0006 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0002
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0222 0.0625 0.0698
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0056 0.0062
Brugia malayi Hr1 repeat family protein 0.0006 0.0004 0.0004
Echinococcus multilocularis cyclin dependent kinase 1 0.0024 0.0056 0.0062
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0059
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0386 0.1095 0.1223
Giardia lamblia Cysteine protease 0.0386 0.1095 0.2128
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0125 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0386 0.1095 0.2193
Echinococcus multilocularis FTZ F1 alpha 0.0005 0.0001 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.1494 0.4277 1
Echinococcus granulosus enteropeptidase 0.0006 0.0004 0.0004
Echinococcus granulosus protein kinase C gamma type 0.0006 0.0004 0.0004
Brugia malayi plexin A 0.0016 0.0033 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0005 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0005 0.0001 0.0002
Onchocerca volvulus 0.1494 0.4277 1
Schistosoma mansoni serine/threonine protein kinase 0.0006 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0006
Giardia lamblia Kinase, CMGC CDK 0.0024 0.0056 0.0023
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0149 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0386 0.1095 0.2193
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0042 0.0108 0.0232
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0004
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0006 0.0003 0.0003
Giardia lamblia Hypothetical protein 0.0386 0.1095 0.2128
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0005 0.0001 0.0002
Brugia malayi cathepsin L precursor 0.0386 0.1095 0.1223
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0222 0.0625 0.1443
Schistosoma mansoni hypothetical protein 0.0006 0.0004 0.0004
Plasmodium falciparum serine repeat antigen 5 0.0386 0.1095 0.2546
Schistosoma mansoni cercarial elastase (S01 family) 0.0006 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0006 0.0004 0.0004
Brugia malayi Trypsin family protein 0.0006 0.0004 0.0004
Brugia malayi hypothetical protein 0.0008 0.001 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0005 0.0001 0.0002
Echinococcus granulosus cyclin dependent kinase 5 0.0024 0.0056 0.0062
Giardia lamblia Cathepsin B precursor 0.174 0.4983 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0008 0.0009 0.0005
Plasmodium falciparum protein farnesyltransferase subunit beta 0.002 0.0045 0.0084
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0046 0.0086
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0073 0.0196 0.0219
Schistosoma mansoni plexin 0.0014 0.0026 0.0029
Brugia malayi Papain family cysteine protease containing protein 0.0835 0.2385 0.2663
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0005 0.0001 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0006
Schistosoma mansoni cpg binding protein 0.0032 0.0078 0.0088
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0133 0.0368 0.0411
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0038 0.0095 0.0087
Giardia lamblia Rab geranylgeranyltransferase 0.0058 0.0152 0.0218
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0008 0.0009
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0082

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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