Detailed information for compound 1019948

Basic information

Technical information
  • TDR Targets ID: 1019948
  • Name: 8-(4-chlorophenyl)-8-ethoxy-5-methyl-[1,2,4]o xadiazolo[3,4-c][1,4]thiazin-3-one
  • MW: 324.783 | Formula: C14H13ClN2O3S
  • H donors: 0 H acceptors: 1 LogP: 3.24 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC1(SC=C(n2c1noc2=O)C)c1ccc(cc1)Cl
  • InChi: 1S/C14H13ClN2O3S/c1-3-19-14(10-4-6-11(15)7-5-10)12-16-20-13(18)17(12)9(2)8-21-14/h4-8H,3H2,1-2H3
  • InChiKey: AJWZHXWZYWGYIH-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni amine GPCR 0.0057 0.0129 0.034
Echinococcus granulosus g protein coupled receptor 0.0057 0.0129 0.034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0129 0.034
Brugia malayi Dopamine receptor protein 1 0.0057 0.0129 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0129 0.034
Schistosoma mansoni ATP-binding cassette transporter 0.0078 0.02 0.0525
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0214 0.0651 1
Plasmodium vivax glutathione reductase, putative 0.0037 0.0062 0.1042
Entamoeba histolytica hypothetical protein 0.0025 0.0021 0.0328
Schistosoma mansoni nAChR subunit 0.0037 0.0063 0.0165
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0249 0.0768 0.2016
Echinococcus granulosus biogenic amine 5HT receptor 0.0057 0.0129 0.034
Brugia malayi DKFZp564C0469 protein 0.0032 0.0045 0.0045
Schistosoma mansoni opsin-like receptor 0.0057 0.0129 0.034
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0379 1
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0129 0.034
Echinococcus multilocularis orexin receptor type 2 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Echinococcus granulosus glycine receptor subunit alpha 1 0.0037 0.0063 0.0165
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0051 0.0109 0.1798
Brugia malayi hypothetical protein 0.0078 0.0199 0.0199
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus 7tm_1 domain containing protein 0.0057 0.0129 0.034
Echinococcus granulosus expressed conserved protein 0.0201 0.0608 0.1596
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0004 0.001
Schistosoma mansoni nAChR subunit 0.0037 0.0063 0.0165
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0038 0.0066 0.0381
Loa Loa (eye worm) glutathione reductase 0.0037 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Brugia malayi excitatory GABA receptor EXP-1A 0.0037 0.0063 0.0063
Brugia malayi metabotropic glutamate receptor type 2 0.004 0.0073 0.0073
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0063 0.0148 0.0148
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.0066 0.1112
Onchocerca volvulus 0.0037 0.0063 0.0151
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0085 0.022 0.8556
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.0066 0.1112
Schistosoma mansoni tyrosine kinase 0.004 0.0073 0.019
Loa Loa (eye worm) hypothetical protein 0.0197 0.0595 0.0595
Brugia malayi glutathione reductase 0.0037 0.0062 0.0062
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0119 0.0334 0.0876
Loa Loa (eye worm) hypothetical protein 0.0156 0.0457 0.0457
Brugia malayi jmjC domain containing protein 0.0068 0.0165 0.0165
Onchocerca volvulus 0.0041 0.0076 0.0186
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0136 0.0136
Echinococcus granulosus intermediate filament protein 0.0031 0.0042 0.011
Schistosoma mansoni chromosome transmission fidelity factor 0.0032 0.0045 0.0117
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Onchocerca volvulus 0.0197 0.0595 0.1551
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0032 0.0045 0.2075
Echinococcus granulosus zinc finger protein 0.002 0.0007 0.0017
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0031 0.0081
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0037 0.0063 0.0165
Echinococcus multilocularis tar DNA binding protein 0.0142 0.0411 0.1081
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0125 0.0125
Echinococcus multilocularis G-protein coupled receptor, putative 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0197 0.0595 0.0595
Echinococcus multilocularis neuropeptide receptor 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.1162 0.3808 0.3808
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0129 0.034
Echinococcus granulosus neuropeptide receptor A26 0.0057 0.0129 0.034
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0083 0.0215 0.0215
Echinococcus multilocularis neuropeptide receptor A26 0.0057 0.0129 0.034
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0165 0.0432
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0057 0.0129 0.034
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0132 0.0379 0.0379
Echinococcus granulosus fmrfamide receptor 0.0057 0.0129 0.034
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0021 0.0564
Brugia malayi RE15519p 0.0057 0.0129 0.0129
Mycobacterium leprae Probable lipase LipE 0.0041 0.0076 0.1942
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0037 0.0063 0.0165
Echinococcus granulosus survival motor neuron protein 1 0.0265 0.082 0.2155
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0063 0.0148 0.3913
Echinococcus multilocularis dro:myosuppressin receptor 0.0057 0.0129 0.034
Schistosoma mansoni hypothetical protein 0.0088 0.0233 0.0613
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0064 0.0167
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0037 0.0063 0.0063
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0037 0.0063 0.0165
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0006 0.0015
Schistosoma mansoni hypothetical protein 0.0057 0.0129 0.034
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0076 0.2012
Schistosoma mansoni amine GPCR 0.0057 0.0129 0.034
Plasmodium vivax amine transporter, putative 0.0197 0.0595 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0073
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0063 0.0148 0.0148
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0076 0.0932
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0129 0.034
Onchocerca volvulus 0.0057 0.0129 0.0326
Loa Loa (eye worm) hypothetical protein 0.0288 0.0899 0.0899
Brugia malayi G protein-coupled receptor 0.0057 0.0129 0.0129
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Plasmodium falciparum flap endonuclease 1 0.0028 0.0031 0.0517
Schistosoma mansoni DNA ligase IV 0.0032 0.0045 0.0117
Echinococcus granulosus lysine specific demethylase 5A 0.0068 0.0165 0.0432
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0014 0.0231
Onchocerca volvulus 0.0057 0.0129 0.0326
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0078 0.02 0.0525
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0129 0.034
Schistosoma mansoni peptidase Clp (S14 family) 0.0083 0.0215 0.0566
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Entamoeba histolytica Ran family GTPase 0.0023 0.0014 0.0211
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0129 0.034
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0119 0.0334 0.0876
Loa Loa (eye worm) hypothetical protein 0.1544 0.5081 0.5081
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0037 0.0063 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0136 0.0358
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0129 0.034
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0348 0.0348
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0136 0.3599
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0063 0.0166
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0014 0.0014
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0057 0.0129 0.034
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0063 0.0148 0.039
Brugia malayi Importin beta-1 subunit 0.0031 0.0041 0.0041
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0249 0.0768 0.2016
Mycobacterium ulcerans hypothetical protein 0.0041 0.0076 0.1254
Schistosoma mansoni tyrosine kinase 0.004 0.0073 0.019
Schistosoma mansoni hypothetical protein 0.0057 0.0129 0.034
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0197 0.0595 0.1564
Echinococcus granulosus importin subunit beta 1 0.0031 0.0041 0.0107
Schistosoma mansoni hypothetical protein 0.0038 0.0066 0.0173
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0412 0.1081
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0201 0.0608 1
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0037 0.0063 0.0063
Trypanosoma brucei C-8 sterol isomerase, putative 0.3021 1 1
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0379 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0057 0.0129 0.034
Brugia malayi hypothetical protein 0.0197 0.0595 0.0595
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1162 0.3808 1
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.004 0.0073 0.0073
Echinococcus multilocularis sodium and chloride dependent glycine 0.0197 0.0595 0.1564
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0031 0.0517
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0076 0.2012
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0057 0.0129 0.034
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Plasmodium falciparum thioredoxin reductase 0.0037 0.0062 0.1042
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0129 0.034
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0279 0.0869 0.2283
Schistosoma mansoni ran 0.0023 0.0014 0.0036
Brugia malayi Casein kinase II, alpha chain 0.0132 0.0379 0.0379
Toxoplasma gondii thioredoxin reductase 0.0037 0.0062 0.1042
Brugia malayi ORL1-like opioid receptor 0.0057 0.0129 0.0129
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0142 0.0411 0.0411
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0037 0.0063 0.0165
Echinococcus multilocularis sterol regulatory element binding protein 0.0092 0.0244 0.0642
Schistosoma mansoni biogenic amine receptor 0.0057 0.0129 0.034
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0067
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0051 0.0109 0.1337
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1162 0.3808 0.3808
Mycobacterium tuberculosis Conserved protein 0.0041 0.0076 0.0932
Trichomonas vaginalis replication factor C large subunit, putative 0.0032 0.0045 0.1179
Schistosoma mansoni zinc finger protein 0.002 0.0007 0.0017
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0146 0.0383
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0197 0.0595 0.9775
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0066 0.0158 0.0415
Schistosoma mansoni hypothetical protein 0.0088 0.0233 0.0613
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.0078 0.0199 0.0522
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0132 0.0379 0.6366
Loa Loa (eye worm) norepinephrine transporter 0.1162 0.3808 0.3808
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0197 0.0595 0.0595
Echinococcus multilocularis snurportin 1 0.0327 0.1028 0.27
Schistosoma mansoni opsin-like receptor 0.0057 0.0129 0.034
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0076 0.2012
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0073
Brugia malayi Serotonin receptor 0.0057 0.0129 0.0129
Brugia malayi Melatonin receptor type 1A 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0073
Schistosoma mansoni neuropeptide receptor 0.0057 0.0129 0.034
Entamoeba histolytica acyl-coA synthetase, putative 0.0051 0.0109 0.168
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0288 0.0899 0.2361
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0057 0.0129 0.0129
Echinococcus granulosus serotonin transporter 0.1162 0.3808 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0197 0.0595 0.0595
Schistosoma mansoni intermediate filament proteins 0.0031 0.0042 0.011
Onchocerca volvulus 0.0037 0.0063 0.0151
Onchocerca volvulus 0.0057 0.0129 0.0326
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0057 0.0129 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0129 0.034
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0057 0.0129 0.0129
Onchocerca volvulus 0.0032 0.0045 0.0103
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0037 0.0063 0.0165
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0067 0.1027
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0064 0.0167
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0076 0.0932
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.002 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0073
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0125 0.0125
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0063 0.0148 0.2491
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0014 0.0036
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0037 0.0063 0.0063
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0136 0.0358
Schistosoma mansoni biogenic amine receptor 0.0057 0.0129 0.034
Echinococcus granulosus G protein coupled receptor 139 0.0057 0.0129 0.034
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.004 0.0073 0.0073
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0348 0.5716
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0037 0.0063 0.0063
Plasmodium falciparum glutathione reductase 0.0037 0.0062 0.1042
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0136 0.3599
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0109 0.1798
Schistosoma mansoni histamine h1 receptor 0.0057 0.0129 0.034
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0109 0.0109
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0042 0.0042
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0014 0.0036
Schistosoma mansoni nAChR subunit 0.0037 0.0063 0.0165
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0031 0.0812
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0197 0.0595 0.1564
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0078 0.02 0.0525
Echinococcus multilocularis Niemann Pick C1 protein 0.0214 0.0651 0.1709
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0215 0.3617
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0083 0.0215 1
Echinococcus granulosus orexin receptor type 2 0.0057 0.0129 0.034
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0076 0.0932
Echinococcus multilocularis nAChR subunit 0.0037 0.0063 0.0165
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0017 0.0044
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0197 0.0595 0.0595
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0021 0.0564
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0067 0.1764
Onchocerca volvulus 0.0057 0.0129 0.0326
Onchocerca volvulus 0.0057 0.0129 0.0326
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Brugia malayi intermediate filament protein 0.0031 0.0042 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0045 0.0045
Echinococcus multilocularis protein patched 0.0092 0.0244 0.0642
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0074 0.0184 0.0184
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0057 0.0129 0.034
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.018 0.0538 0.1414
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Entamoeba histolytica hypothetical protein 0.0078 0.0199 0.3056
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0037 0.0063 0.0165
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0249 0.0768 0.0768
Mycobacterium tuberculosis Probable reductase 0.0085 0.022 0.2693
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0348 0.0913
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0045
Onchocerca volvulus 0.0057 0.0129 0.0326
Brugia malayi Serine protease Z688.6 precursor 0.0063 0.0148 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0045 0.1179
Echinococcus granulosus receptor type guanylyl cyclase 0.004 0.0073 0.019
Brugia malayi hypothetical protein 0.0265 0.082 0.082
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0215 0.3617
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0014 0.0231
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0094 0.0252 0.3077
Leishmania major extracellular receptor, putative 0.004 0.0073 0.0073
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0129 0.034
Plasmodium falciparum replication factor C subunit 1, putative 0.0032 0.0045 0.0751
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0125 0.0125
Brugia malayi putative neuropeptide receptor NPR1 0.0057 0.0129 0.0129
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0037 0.0063 0.0165
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0088 0.0233 0.0613
Onchocerca volvulus 0.0037 0.0063 0.0151
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0092 0.0244 0.0244
Onchocerca volvulus 0.0037 0.0063 0.0151
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0076 0.0932
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0062 0.0759
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0067 0.1099
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0129 0.034
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0057 0.0129 0.034
Onchocerca volvulus 0.1162 0.3808 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0076 0.0932
Plasmodium falciparum importin beta, putative 0.0031 0.0041 0.0683
Loa Loa (eye worm) G-protein coupled receptor 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0045
Brugia malayi G-protein coupled receptor 0.0057 0.0129 0.0129
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.0045 0.1179
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.012 0.0315
Echinococcus granulosus neuropeptides capa receptor 0.0057 0.0129 0.034
Treponema pallidum sodium- and chloride- dependent transporter 0.1162 0.3808 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0119 0.0334 0.0876
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Onchocerca volvulus 0.0031 0.0042 0.0095
Mycobacterium tuberculosis Conserved protein 0.0041 0.0076 0.0932
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0136 0.3599
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0076 0.02
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni inositol monophosphatase 0.0039 0.0067 0.0176
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0021 0.0564
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.0045 0.1179
Echinococcus granulosus snurportin 1 0.0327 0.1028 0.27
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0034 0.0571
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0197 0.0595 0.0595
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0197 0.0595 0.1564
Brugia malayi G-protein coupled receptor 0.0057 0.0129 0.0129
Echinococcus granulosus Niemann Pick C1 protein 0.0306 0.0957 0.2512
Brugia malayi Metabotropic glutamate receptor precursor. 0.004 0.0073 0.0073
Echinococcus granulosus serotonin receptor 0.0057 0.0129 0.034
Echinococcus granulosus replication factor c subunit 1 0.0032 0.0045 0.0117
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0412 0.1081
Loa Loa (eye worm) ACC-1 protein 0.0037 0.0063 0.0063
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0051 0.0109 0.1798
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0119 0.0334 0.0876
Schistosoma mansoni protein kinase 0.004 0.0073 0.019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0129 0.034
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.3021 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0057 0.0129 0.034
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0085 0.022 0.2693
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0129 0.034
Schistosoma mansoni adenoreceptor 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0087
Echinococcus multilocularis glutamate receptor 2 0.0078 0.02 0.0525
Schistosoma mansoni nAChR subunit 0.0037 0.0063 0.0165
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0037 0.0063 0.0165
Schistosoma mansoni hypothetical protein 0.018 0.0538 0.1414
Onchocerca volvulus Neuropeptide F receptor homolog 0.0057 0.0129 0.0326
Brugia malayi Bromodomain containing protein 0.004 0.0072 0.0072
Plasmodium falciparum amino acid transporter, putative 0.0197 0.0595 1
Loa Loa (eye worm) hypothetical protein 0.0265 0.082 0.082
Echinococcus multilocularis glycine receptor subunit beta 0.0037 0.0063 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0045 0.1179
Plasmodium vivax importin-beta 2, putative 0.0031 0.0041 0.0683
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0037 0.0063 0.0165
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0076 0.0076
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0083 0.0215 0.0566
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0045 0.1179
Entamoeba histolytica casein kinase, putative 0.0132 0.0379 0.5823
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0288 0.0899 0.0899
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0067 0.1123
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0136 0.0136
Loa Loa (eye worm) inositol-1 0.0039 0.0067 0.0067
Echinococcus granulosus nmda type glutamate receptor 0.004 0.0073 0.019
Brugia malayi Probable ClpP-like protease 0.0083 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) ACC-1 protein 0.0037 0.0063 0.0063
Schistosoma mansoni glutamate receptor NMDA 0.0078 0.02 0.0525
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0249 0.0768 0.2016
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0032 0.0045 0.0045
Brugia malayi metabotropic GABA-B receptor subtype 2 0.004 0.0073 0.0073
Trypanosoma brucei protein kinase, putative 0.0059 0.0136 0.0136
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0197 0.0595 0.1564
Loa Loa (eye worm) hypothetical protein 0.0112 0.0313 0.0313
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0412 0.1081
Brugia malayi Pax transcription activation domain interacting protein 0.0032 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Brugia malayi Inositol-1 0.0039 0.0067 0.0067
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.012 0.1468
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0006 0.0006
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.004 0.0073 0.0176
Loa Loa (eye worm) hypothetical protein 0.0051 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0156 0.0457 0.0457
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0085 0.022 0.2693
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0067 0.3104
Schistosoma mansoni hypothetical protein 0.0057 0.0129 0.034
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0063 0.0148 0.2279
Brugia malayi neuropeptide F receptor 0.0057 0.0129 0.0129
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0379 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0197 0.0595 0.1564
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0197 0.0595 0.1564
Echinococcus multilocularis survival motor neuron protein 1 0.0265 0.082 0.2155
Loa Loa (eye worm) hypothetical protein 0.0042 0.008 0.008
Schistosoma mansoni topbp1 0.0032 0.0045 0.0117
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0057 0.0129 0.034
Schistosoma mansoni myosin xvIII 0.0057 0.0129 0.034
Schistosoma mansoni neuropeptide receptor 0.0057 0.0129 0.034
Brugia malayi sulfakinin receptor protein 0.0057 0.0129 0.0129
Echinococcus multilocularis sodium and chloride dependent glycine 0.0197 0.0595 0.1564
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0129 0.034
Plasmodium vivax replication factor C subunit 1, putative 0.0032 0.0045 0.0751
Echinococcus multilocularis G protein coupled receptor 139 0.0057 0.0129 0.034
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0136 0.2291
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0201 0.0608 0.1597
Schistosoma mansoni opsin-like receptor 0.0057 0.0129 0.034
Loa Loa (eye worm) RNA binding protein 0.0142 0.0411 0.0411
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0057 0.0129 0.0326
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0197 0.0595 0.0595
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0201 0.0608 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.002 0.0006 0.0006
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0067
Echinococcus granulosus somatostatin receptor 0.0057 0.0129 0.034
Echinococcus multilocularis fmrfamide receptor 0.0057 0.0129 0.034
Schistosoma mansoni glutamate receptor AMPA 0.0078 0.02 0.0525
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0063 0.0148 0.2279
Schistosoma mansoni biogenic amine (5HT) receptor 0.0057 0.0129 0.034
Echinococcus multilocularis replication factor c subunit 1 0.0032 0.0045 0.0117
Echinococcus multilocularis fmrfamide receptor 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0197 0.0595 0.0595
Echinococcus multilocularis glutamate receptor 2 0.004 0.0073 0.019
Brugia malayi RNA recognition motif domain containing protein 0.0142 0.0411 0.0411
Plasmodium vivax hypothetical protein, conserved 0.0197 0.0595 1
Toxoplasma gondii CMGC kinase, CK2 family 0.0132 0.0379 0.6366
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Schistosoma mansoni growth hormone secretagogue receptor 0.0057 0.0129 0.034
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0411 0.1081
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0197 0.0595 0.1564
Echinococcus granulosus alpha 1A adrenergic receptor 0.0057 0.0129 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0148 0.3913
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.0045 0.1179
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0412 0.1081
Onchocerca volvulus 0.0057 0.0129 0.0326
Trypanosoma cruzi extracellular receptor, putative 0.004 0.0073 0.0073
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0057 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.0054 0.0118 0.0311
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0076 0.2012
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0109 0.0109
Brugia malayi AKH receptor 0.0057 0.0129 0.0129
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0037 0.0063 0.0063
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0014 0.0014
Loa Loa (eye worm) TYRA-2 protein 0.0057 0.0129 0.0129
Schistosoma mansoni survival motor neuron protein 0.0054 0.0118 0.0311
Brugia malayi Receptor family ligand binding region containing protein 0.004 0.0073 0.0073
Brugia malayi Dopamine receptor protein 2 0.0057 0.0129 0.0129
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0348 0.5716
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0129 0.034
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0136 0.3599
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0129 0.034
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0411 0.1081
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0201 0.0608 0.1597
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0063 0.0063
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0288 0.0899 0.2361
Brugia malayi neuropeptide F receptor 0.0057 0.0129 0.0129
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0031 0.0517
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0379 1
Onchocerca volvulus 0.0197 0.0595 0.1551
Echinococcus multilocularis neuropeptide receptor 0.0057 0.0129 0.034
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0076 0.0932
Echinococcus granulosus peptide allatostatin:somatostatin 0.0057 0.0129 0.034
Brugia malayi GnHR receptor homolog 0.0057 0.0129 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus hypothetical protein 0.0779 0.2534 0.6656
Brugia malayi Bromodomain containing protein 0.0078 0.0199 0.0199
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0053 0.0893
Echinococcus granulosus nAChR subunit 0.0037 0.0063 0.0165
Leishmania major importin beta-1 subunit, putative 0.0025 0.0021 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0129 0.034
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0348 0.5837
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0085 0.022 0.2693
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0041 0.0041
Brugia malayi MAP kinase sur-1 0.0059 0.0136 0.0136
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0142 0.0412 0.0412
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0348 0.0913
Schistosoma mansoni nAChR subunit 0.0037 0.0063 0.0165
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0076 0.0932
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0037 0.0063 0.0165
Echinococcus multilocularis neuropeptide s receptor 0.0057 0.0129 0.034
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0078 0.02 0.0525
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0078 0.02 0.0525
Schistosoma mansoni hypothetical protein 0.0088 0.0233 0.0613
Onchocerca volvulus 0.0057 0.0129 0.0326
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0045 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0129 0.034
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Toxoplasma gondii hypothetical protein 0.0197 0.0595 1
Loa Loa (eye worm) serotonin transporter b 0.1162 0.3808 0.3808
Echinococcus multilocularis musashi 0.0031 0.0042 0.011
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0197 0.0595 0.1564
Schistosoma mansoni metabotropic glutamate receptor 0.004 0.0073 0.019
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0348 0.425
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0032 0.0045 0.0493
Schistosoma mansoni inositol monophosphatase 0.0039 0.0067 0.0176
Echinococcus granulosus atrial natriuretic peptide receptor 0.004 0.0073 0.019
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0037 0.0063 0.0165
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Onchocerca volvulus 0.004 0.0073 0.0176
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0136 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0045 0.1179
Schistosoma mansoni sodium-dependent amino acid transporter 0.0197 0.0595 0.1564
Schistosoma mansoni sodium/chloride dependent transporter 0.0199 0.06 0.1576
Echinococcus multilocularis glycine receptor subunit beta 0.0037 0.0063 0.0165
Brugia malayi Receptor family ligand binding region containing protein 0.004 0.0073 0.0073
Echinococcus granulosus g-protein coupled receptor 0.0057 0.0129 0.034
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0379 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0057 0.0129 0.034
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0066 0.0066
Loa Loa (eye worm) GABA receptor subunit 0.002 0.0006 0.0006
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0083 0.0215 0.3617
Echinococcus granulosus g protein coupled receptor 0.0057 0.0129 0.034
Plasmodium falciparum transporter, putative 0.0197 0.0595 1
Loa Loa (eye worm) glutamate receptor 1 0.0078 0.02 0.02
Schistosoma mansoni amine GPCR 0.0057 0.0129 0.034
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0037 0.0063 0.0165
Brugia malayi Dopamine receptor 0.0057 0.0129 0.0129
Giardia lamblia Serine peptidase, putative 0.0063 0.0148 0.3913
Mycobacterium tuberculosis Conserved protein 0.0041 0.0076 0.0932
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0348 0.0913
Echinococcus granulosus neuropeptide FF receptor 2 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Schistosoma mansoni biogenic amine receptor 0.0057 0.0129 0.034
Echinococcus multilocularis glutamate receptor 2 0.0119 0.0334 0.0876
Echinococcus granulosus tachykinin peptides receptor 99D 0.0057 0.0129 0.034
Echinococcus granulosus geminin 0.018 0.0538 0.1414
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0197 0.0595 0.1564
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0327 0.1028 0.1028
Leishmania major hypothetical protein, conserved 0.0041 0.0076 0.0076
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0057 0.0129 0.034
Plasmodium vivax unspecified product 0.0132 0.0379 0.6366
Onchocerca volvulus 0.0057 0.0129 0.0326
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0067 0.0176
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0057 0.0129 0.0129
Brugia malayi Niemann-Pick C1 protein precursor 0.0214 0.0651 0.0651
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0215 0.3617
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0379 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0129 0.034
Echinococcus granulosus allatostatin A receptor 0.0057 0.0129 0.034
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0063 0.0148 0.039
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0066 0.0158 0.0415
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0066
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.0199 0.0522
Echinococcus multilocularis neuropeptides capa receptor 0.0057 0.0129 0.034
Schistosoma mansoni flap endonuclease-1 0.0025 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Schistosoma mansoni glutamate receptor kainate 0.0078 0.02 0.0525
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0076 0.2012
Loa Loa (eye worm) beta-lactamase 0.0041 0.0076 0.0076
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0057 0.0129 0.034
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0109 0.1337
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0076 0.1254
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0066
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0197 0.0595 0.1564
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0109 0.0109
Schistosoma mansoni nAChR subunit 0.0037 0.0063 0.0165
Leishmania major GTP-binding protein, putative 0.0023 0.0014 0.0014
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0014 0.0231
Onchocerca volvulus 0.0051 0.0109 0.0273
Echinococcus granulosus lamin 0.0031 0.0042 0.011
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0201 0.0608 0.7435
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Schistosoma mansoni patched 1 0.0092 0.0244 0.0642
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus granulosus g protein coupled receptor 0.0057 0.0129 0.034
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Echinococcus granulosus sterol regulatory element binding protein 0.0092 0.0244 0.0642
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0249 0.0768 0.2016
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0119 0.0334 0.0876
Brugia malayi hypothetical protein 0.004 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.1162 0.3808 0.3808
Brugia malayi Serine carboxypeptidase S28 family protein 0.0288 0.0899 0.0899
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0119 0.0334 0.0876
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0214 0.0651 0.0651
Echinococcus granulosus glutamate NMDA receptor subunit 0.0078 0.02 0.0525
Echinococcus multilocularis nmda type glutamate receptor 0.0279 0.0869 0.2283
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0062 0.1042
Echinococcus multilocularis expressed conserved protein 0.0201 0.0608 0.1596
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0051 0.0109 0.1798
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0094 0.0252 0.3077
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0063 0.0063
Giardia lamblia Kinase, CMGC CK2 0.0132 0.0379 1
Echinococcus multilocularis metabotropic glutamate receptor 2 0.004 0.0073 0.019
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0037 0.0063 0.0165
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0031 0.0031
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0031 0.0812
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0059 0.0724
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0062 0.0062
Entamoeba histolytica hypothetical protein 0.0078 0.0199 0.3056
Entamoeba histolytica hypothetical protein 0.0078 0.0199 0.3056
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0197 0.0595 0.0595
Echinococcus granulosus metabotropic glutamate receptor 2 0.004 0.0073 0.019
Brugia malayi Tachykinin-like peptides receptor 99D 0.0057 0.0129 0.0129
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Echinococcus multilocularis lamin 0.0031 0.0042 0.011
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0032 0.0045 0.0687
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0411 0.1081
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Brugia malayi beta-lactamase family protein 0.0041 0.0076 0.0076
Echinococcus granulosus glutamate receptor 2 0.004 0.0073 0.019
Schistosoma mansoni metabotropic glutamate receptor 0.004 0.0073 0.019
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0037 0.0063 0.0165
Leishmania major casein kinase II, putative 0.0132 0.0379 0.0379
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0066
Onchocerca volvulus 0.0031 0.0042 0.0095
Trypanosoma cruzi C-8 sterol isomerase, putative 0.3021 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0348 0.5716
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0129 0.034
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0076 0.1942
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0129 0.034
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0379 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.012 0.1468
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0119 0.0334 0.0876
Onchocerca volvulus 0.0057 0.0129 0.0326
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0249 0.0768 0.2016
Echinococcus granulosus glutamate receptor 2 0.0119 0.0334 0.0876
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0109 0.3462
Schistosoma mansoni jumonji domain containing protein 0.0066 0.0158 0.0415
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0136 0.0136
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0051 0.0109 0.1798
Brugia malayi RNA binding protein 0.0142 0.0411 0.0411
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0129 0.034
Brugia malayi RNA, U transporter 1 0.0087 0.0229 0.0229
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.0066 0.1088
Echinococcus multilocularis geminin 0.018 0.0538 0.1414
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0197 0.0595 1
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0078 0.02 0.0525
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0057 0.0129 0.034
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0014 0.0014
Echinococcus granulosus neuropeptide s receptor 0.0057 0.0129 0.034
Entamoeba histolytica hypothetical protein 0.004 0.0073 0.1114
Schistosoma mansoni amine GPCR 0.0057 0.0129 0.034
Echinococcus multilocularis muscleblind protein 1 0.0156 0.0457 0.1201
Schistosoma mansoni lamin 0.0031 0.0042 0.011
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Trypanosoma brucei trypanothione reductase 0.0037 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0781 0.2541 0.2541
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0037 0.0063 0.0165
Mycobacterium tuberculosis Probable dehydrogenase 0.0085 0.022 0.2693
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus multilocularis serotonin receptor 0.0781 0.2541 0.6673
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0148 0.3913
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0067 0.0176
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0076 0.02
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0078 0.02 0.0525
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.0045 0.1179
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0057 0.0129 0.034
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0136 0.0358
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0021 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0076 0.0076
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0004 0.001
Echinococcus multilocularis g-protein coupled receptor 0.0057 0.0129 0.034
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0063 0.0148 0.3913
Schistosoma mansoni sodium/chloride dependent transporter 0.1162 0.3808 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0034 0.0089
Echinococcus granulosus flap endonuclease 1 0.0028 0.0031 0.0081
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0053 0.0653
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0146 0.0383
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0057 0.0129 0.0129
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Echinococcus multilocularis lysine specific demethylase 5A 0.0066 0.0158 0.0415
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0067
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0076 0.0076
Toxoplasma gondii ATPase, AAA family protein 0.0032 0.0045 0.0751
Brugia malayi follicle stimulating hormone receptor 0.0057 0.0129 0.0129
Loa Loa (eye worm) neuropeptide F receptor 0.0057 0.0129 0.0129
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0067 0.1764
Schistosoma mansoni topbp1 0.0032 0.0045 0.0117
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0063 0.0148 0.039
Echinococcus granulosus biogenic amine 5HT receptor 0.0781 0.2541 0.6673
Schistosoma mansoni neuropeptide receptor 0.0057 0.0129 0.034
Echinococcus granulosus dro:myosuppressin receptor 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0288 0.0899 0.0899
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Entamoeba histolytica hypothetical protein 0.0078 0.0199 0.3056
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0109 0.1798
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0076 0.02
Echinococcus granulosus casein kinase ii subunit alpha 0.0132 0.0379 0.0995
Schistosoma mansoni glutamate receptor NMDA 0.0119 0.0334 0.0876
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0244 0.6446
Echinococcus granulosus nAChR subunit 0.002 0.0006 0.0015
Toxoplasma gondii hypothetical protein 0.0197 0.0595 1
Schistosoma mansoni bromodomain containing protein 0.0066 0.0158 0.0416
Schistosoma mansoni importin beta-1 0.0031 0.0041 0.0107
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0136 0.0358
Echinococcus granulosus sodium and chloride dependent glycine 0.0197 0.0595 0.1564
Onchocerca volvulus 0.0057 0.0129 0.0326
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Onchocerca volvulus 0.0041 0.0076 0.0186
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0288 0.0899 0.2361
Loa Loa (eye worm) hypothetical protein 0.0092 0.0244 0.0244
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0031 0.0031
Brugia malayi G protein-coupled receptor F59B2.13 0.0057 0.0129 0.0129
Echinococcus multilocularis neuropeptide Y receptor 0.0057 0.0129 0.034
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0057 0.0129 0.034
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0037 0.0063 0.0063
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0014 0.0014
Brugia malayi Glutamate receptor 2 precursor 0.0078 0.02 0.02
Onchocerca volvulus 0.0037 0.0063 0.0151
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0412 0.1081
Brugia malayi putative neuropeptide receptor 0.0057 0.0129 0.0129
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0014 0.0362
Echinococcus multilocularis casein kinase ii subunit alpha 0.0132 0.0379 0.0995
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0197 0.0595 0.0595
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0109 0.0109
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0063 0.0166
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0078 0.02 0.0525
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0165 0.0432
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0045
Brugia malayi CHE-14 protein 0.0092 0.0244 0.0244
Brugia malayi Thioredoxin reductase 0.0037 0.0062 0.0062
Trypanosoma cruzi casein kinase II, putative 0.0132 0.0379 0.0379
Brugia malayi PHD-finger family protein 0.0026 0.0025 0.0025
Brugia malayi Glutamate receptor 1 precursor 0.0078 0.02 0.02
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0063 0.0148 0.3913
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0059 0.0724
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0057 0.0129 0.0129
Echinococcus multilocularis nibrin 0.0032 0.0045 0.0117
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0197 0.0595 0.1564
Mycobacterium tuberculosis Probable oxidoreductase 0.0094 0.0252 0.3077
Plasmodium falciparum casein kinase 2, alpha subunit 0.0132 0.0379 0.6366
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0034 0.0571
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0908 0.2962 0.778
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0076 0.0076
Echinococcus granulosus neuropeptides capa receptor 0.0057 0.0129 0.034
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0215 0.303
Echinococcus granulosus Protein patched homolog 1 0.0092 0.0244 0.0642
Echinococcus multilocularis allatostatin A receptor 0.0057 0.0129 0.034
Onchocerca volvulus 0.0054 0.0118 0.0297
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0041 0.0683
Loa Loa (eye worm) glutamate receptor 2 0.0078 0.02 0.02
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0348 0.0913
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0059 0.0724
Echinococcus multilocularis nAChR subunit 0.002 0.0006 0.0015
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0063 0.0063
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0037 0.0063 0.0063
Onchocerca volvulus 0.004 0.0073 0.0176
Loa Loa (eye worm) solute carrier family 6 member 4 0.1162 0.3808 0.3808
Schistosoma mansoni alpha-1 adrenergic receptor 0.0057 0.0129 0.034
Mycobacterium ulcerans hypothetical protein 0.0051 0.0109 0.1798
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0073
Leishmania major C-8 sterol isomerase-like protein 0.3021 1 1
Schistosoma mansoni amine GPCR 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0056 0.0125 0.0125
Echinococcus granulosus lamin dm0 0.0031 0.0042 0.011
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0094 0.0252 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0057 0.0129 0.034
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0057 0.0129 0.034
Brugia malayi Guanylyl cyclase protein 23 0.004 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.004 0.0072 0.0072
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0411 0.1081
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0057 0.0129 0.034
Echinococcus granulosus glutamate receptor subunit protein glur 0.0078 0.02 0.0525
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0076 0.1254
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0215 0.303
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0057 0.0129 0.034
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0032 0.0045 0.0751
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0197 0.0595 0.0595
Loa Loa (eye worm) hypothetical protein 0.0051 0.0109 0.0109
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0083 0.0215 0.8334
Onchocerca volvulus Putative nachr subunit 0.0249 0.0768 0.2005
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0042 0.0042
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0109 0.168
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0017 0.0044
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0197 0.0595 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Onchocerca volvulus 0.0041 0.0076 0.0186
Leishmania major trypanothione reductase 0.0037 0.0062 0.0062
Echinococcus multilocularis serotonin transporter 0.1162 0.3808 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0085 0.022 0.2693
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0109 0.3462
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0197 0.0595 0.0595
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0197 0.0595 0.1564
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0129 0.034
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0136 0.3599
Mycobacterium ulcerans lipase LipD 0.0041 0.0076 0.1254
Schistosoma mansoni glutamate receptor kainate 0.0078 0.02 0.0525
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0215 0.3542
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0031 0.0031
Echinococcus granulosus neuropeptide receptor 0.0057 0.0129 0.034
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0037 0.0063 0.0063
Echinococcus granulosus sex peptide receptor 0.0057 0.0129 0.034
Brugia malayi Serine protease Z688.6 precursor 0.0063 0.0148 0.0148
Echinococcus granulosus nmda type glutamate receptor 0.0279 0.0869 0.2283
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0249 0.0768 0.0768
Onchocerca volvulus 0.0197 0.0595 0.1551
Schistosoma mansoni nAChR subunit 0.0037 0.0063 0.0165
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0076 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0129 0.034
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0197 0.0595 0.1564
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.0199 0.0522
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0197 0.0595 0.1564
Loa Loa (eye worm) melatonin receptor type 1A 0.0057 0.0129 0.0129
Toxoplasma gondii hypothetical protein 0.0029 0.0034 0.0571
Echinococcus multilocularis metabotropic glutamate receptor 5 0.004 0.0073 0.019
Echinococcus granulosus glycine receptor subunit alpha 1 0.0037 0.0063 0.0165
Echinococcus multilocularis lamin dm0 0.0031 0.0042 0.011
Echinococcus multilocularis protein dispatched 1 0.0105 0.0287 0.0755
Echinococcus multilocularis conserved hypothetical protein 0.0722 0.2344 0.6155
Giardia lamblia Thymus-specific serine protease precursor 0.0063 0.0148 0.3913
Echinococcus multilocularis NMDA receptor 0.0078 0.02 0.0525
Loa Loa (eye worm) G-protein coupled receptor 0.0057 0.0129 0.0129
Schistosoma mansoni neuropeptide receptor 0.0057 0.0129 0.034
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0066 0.0809
Echinococcus multilocularis Niemann Pick C1 protein 0.0306 0.0957 0.2512
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0059 0.0724
Schistosoma mansoni neuropeptide f receptor 76f 0.0057 0.0129 0.034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0129 0.034
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Onchocerca volvulus 0.0037 0.0063 0.0151
Brugia malayi larval opioid receptor 0.0057 0.0129 0.0129
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0197 0.0595 0.0595
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0411 0.1081
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Brugia malayi Cation transporter family protein 0.0037 0.0063 0.0063
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0057 0.0129 0.034
Echinococcus granulosus nibrin 0.0032 0.0045 0.0117
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0057 0.0129 0.034
Echinococcus granulosus muscleblind protein 0.0156 0.0457 0.1201
Echinococcus multilocularis muscleblind protein 0.0156 0.0457 0.1201
Onchocerca volvulus 0.0057 0.0129 0.0326
Loa Loa (eye worm) hypothetical protein 0.0051 0.0109 0.0109
Echinococcus granulosus sodium and chloride dependent glycine 0.0197 0.0595 0.1564
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0129 0.034
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0057 0.0129 0.034
Loa Loa (eye worm) LGC-31 protein 0.0037 0.0063 0.0063
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0041 0.0041
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0412 0.1081
Brugia malayi topoisomerase 0.0032 0.0045 0.0045
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0045 0.1179
Onchocerca volvulus 0.0063 0.0148 0.0376
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0129 0.034
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0249 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0045
Trypanosoma cruzi FHA domain containing protein, putative 0.0032 0.0045 0.0045
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0031 0.0031
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0217 0.0662 0.1738
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0073
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0037 0.0063 0.0063
Echinococcus multilocularis receptor type guanylyl cyclase 0.004 0.0073 0.019
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus granulosus glycine receptor subunit alpha 1 0.0037 0.0063 0.0165
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0057 0.0129 0.034
Treponema pallidum DNA ligase (lig) 0.0032 0.0045 0.0117
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) jmjC domain-containing protein 0.0068 0.0165 0.0165
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0063 0.0148 0.0148
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0129 0.034
Echinococcus multilocularis tyrosine kinase 0.004 0.0073 0.019
Echinococcus multilocularis neuropeptide Y receptor 0.0057 0.0129 0.034
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0109 0.0109
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.0199 0.0522
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0136 0.0358
Brugia malayi Cation transporter family protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Brugia malayi Cation transporter family protein 0.0037 0.0063 0.0063
Echinococcus granulosus glycine receptor subunit beta 0.0037 0.0063 0.0165
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Schistosoma mansoni glutamate receptor AMPA 0.0078 0.02 0.0525
Brugia malayi Muscleblind-like protein 0.0156 0.0457 0.0457
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0037 0.0063 0.0165
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0129 0.034
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0215 0.3542
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0067
Schistosoma mansoni neuropeptide F-like receptor 0.0057 0.0129 0.034
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0249 0.0768 0.2016
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0063 0.0148 0.2279
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0042 0.0042
Toxoplasma gondii ABC1 family protein 0.0041 0.0076 0.1281
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0031 0.0473
Schistosoma mansoni hypothetical protein 0.0078 0.02 0.0525
Entamoeba histolytica protein kinase domain containing protein 0.0132 0.0379 0.5823
Loa Loa (eye worm) hypothetical protein 0.0781 0.2541 0.2541
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0063 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0412 0.1081
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus neuropeptide Y receptor 0.0057 0.0129 0.034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0129 0.034
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0057 0.0129 0.0129
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0197 0.0595 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0264 0.0818 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0045
Echinococcus granulosus neuropeptide receptor 0.0057 0.0129 0.034
Brugia malayi hypothetical protein 0.0032 0.0045 0.0045
Loa Loa (eye worm) RGC/RGC protein kinase 0.004 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0063 0.0148 0.0148
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0215 0.0566
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0073
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0032 0.0045 0.0735
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0041 0.0107
Loa Loa (eye worm) TAR-binding protein 0.0142 0.0411 0.0411
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0057 0.0129 0.034
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0063 0.0063
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0119 0.0334 0.0876
Schistosoma mansoni biogenic amine (5HT) receptor 0.0781 0.2541 0.6673
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0129 0.034
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.012 0.0315
Brugia malayi Serotonin receptor 0.0539 0.1733 0.1733
Brugia malayi hypothetical protein 0.0032 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0066
Echinococcus multilocularis neuropeptide FF receptor 2 0.0057 0.0129 0.034
Brugia malayi Flap endonuclease-1 0.0028 0.0031 0.0031
Trichomonas vaginalis ran, putative 0.0023 0.0014 0.0362
Echinococcus granulosus tyrosine kinase 0.004 0.0073 0.019
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.012 0.3954
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0037 0.0063 0.0063
Echinococcus multilocularis zinc finger protein 0.002 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.004
Schistosoma mansoni glutamate receptor kainate 0.0078 0.02 0.0525
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.0045 0.0045
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0118 0.0118
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.004 0.0073 0.0073
Echinococcus multilocularis neuropeptides capa receptor 0.0057 0.0129 0.034
Onchocerca volvulus 0.0057 0.0129 0.0326
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.0045 0.0045
Chlamydia trachomatis glutamine binding protein 0.0201 0.0608 1
Brugia malayi beta-lactamase 0.0041 0.0076 0.0076
Schistosoma mansoni sodium/chloride dependent transporter 0.0197 0.0595 0.1564
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0037 0.0063 0.0165
Echinococcus granulosus glycine receptor subunit beta 0.0037 0.0063 0.0165
Onchocerca volvulus 0.0057 0.0129 0.0326
Echinococcus granulosus tar DNA binding protein 0.0142 0.0411 0.1081
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Brugia malayi jmjC domain containing protein 0.0066 0.0158 0.0158
Loa Loa (eye worm) RGC/RGC protein kinase 0.004 0.0073 0.0073
Echinococcus multilocularis somatostatin receptor 0.0057 0.0129 0.034
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0109 0.168
Schistosoma mansoni protein kinase 0.0132 0.0379 0.0995
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0076 0.1281
Schistosoma mansoni neuropeptide F-like receptor 0.0057 0.0129 0.034
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0057 0.0129 0.034
Schistosoma mansoni lamin 0.0031 0.0042 0.011
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0067 0.1764
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0073
Trichomonas vaginalis esterase, putative 0.0041 0.0076 0.2012
Trypanosoma brucei Casein kinase II 0.0132 0.0379 0.0379
Entamoeba histolytica hypothetical protein 0.002 0.0006 0.0085
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0083 0.0215 0.0566
Echinococcus multilocularis nmda type glutamate receptor 0.004 0.0073 0.019
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0109 0.1798
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0197 0.0595 0.1564
Onchocerca volvulus 0.0057 0.0129 0.0326
Echinococcus multilocularis serotonin receptor 0.0781 0.2541 0.6673
Brugia malayi hypothetical protein 0.0057 0.0129 0.0129
Echinococcus multilocularis sex peptide receptor 0.0057 0.0129 0.034
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0057 0.0129 0.034
Entamoeba histolytica hypothetical protein 0.0032 0.0045 0.0687
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0073
Schistosoma mansoni ran 0.0023 0.0014 0.0036
Giardia lamblia Replication factor C, subunit 1 0.0032 0.0045 0.1179
Brugia malayi beta-lactamase family protein 0.0041 0.0076 0.0076
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0017 0.0044
Brugia malayi TAR-binding protein 0.0142 0.0411 0.0411
Loa Loa (eye worm) RGC/RGC protein kinase 0.004 0.0073 0.0073
Onchocerca volvulus 0.0057 0.0129 0.0326
Schistosoma mansoni hypothetical protein 0.0057 0.0129 0.034
Onchocerca volvulus 0.0057 0.0129 0.0326
Loa Loa (eye worm) neuropeptide F receptor 0.0057 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.0327 0.1028 0.27
Echinococcus multilocularis atrial natriuretic peptide receptor 0.004 0.0073 0.019
Mycobacterium ulcerans beta-lactamase 0.0041 0.0076 0.1254
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0142 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0063 0.0063
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0109 0.0109
Echinococcus granulosus Niemann Pick C1 protein 0.0214 0.0651 0.1709
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0148 0.3913
Loa Loa (eye worm) hypothetical protein 0.0057 0.0129 0.0129
Loa Loa (eye worm) glutamate receptor 0.004 0.0073 0.0073
Echinococcus granulosus metabotropic glutamate receptor 5 0.004 0.0073 0.019
Loa Loa (eye worm) hypothetical protein 0.1162 0.3808 0.3808

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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