Detailed information for compound 1127705

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 335.292 | Formula: C16H18NO5P
  • H donors: 3 H acceptors: 5 LogP: 1.05 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: ON(C(=O)c1ccc(cc1)c1ccccc1)CCCP(=O)(O)O
  • InChi: 1S/C16H18NO5P/c18-16(17(19)11-4-12-23(20,21)22)15-9-7-14(8-10-15)13-5-2-1-3-6-13/h1-3,5-10,19H,4,11-12H2,(H2,20,21,22)
  • InChiKey: GPQHBCCFQBXMAZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli 1-deoxy-D-xylulose 5-phosphate reductoisomerase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Neospora caninum 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium yoelii 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS Get druggable targets OG5_130462 All targets in OG5_130462
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras Get druggable targets OG5_130462 All targets in OG5_130462
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Babesia bovis 1-deoxy-D-xylulose 5-phosphate reductoisomerase family protein Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Theileria parva 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium knowlesi 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium berghei 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0184 0.175 0.3529
Entamoeba histolytica DNA topoisomerase II, putative 0.0011 0.0054 0.0274
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0094 0.0094
Brugia malayi Latrophilin receptor protein 2 0.0028 0.0214 0.021
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0116 0.0647
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0094 0.0094
Brugia malayi Pre-SET motif family protein 0.0265 0.2538 0.2535
Echinococcus granulosus MAM 0.0009 0.0033 0.0033
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.033 0.3175 0.6404
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0065 0.0497
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Schistosoma mansoni opsin-like receptor 0.0015 0.0094 0.0189
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0011 0.0054 0.0407
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0094 0.009
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0094 0.0094
Giardia lamblia Heat shock protein HSP 90-alpha 0.006 0.0533 0.2678
Brugia malayi Probable DNA topoisomerase II 0.0011 0.0054 0.005
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Brugia malayi Pre-SET motif family protein 0.0038 0.0318 0.0314
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0116 0.0216
Schistosoma mansoni neurotransmitter gated ion channel 0.0145 0.1367 0.2758
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni ferritin 0.001 0.004 0.008
Echinococcus granulosus nAChR subunit 0.033 0.3175 0.3175
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0145 0.1367 0.1367
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Toxoplasma gondii LsmAD domain-containing protein 0.0015 0.009 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.0242
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0094 0.0094
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0011 0.0054 0.0407
Echinococcus granulosus g protein coupled receptor 0.0015 0.0094 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0059 0.0055
Onchocerca volvulus 0.0145 0.1367 0.1344
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Echinococcus granulosus allatostatin A receptor 0.0015 0.0094 0.0094
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0578 0.0578
Mycobacterium ulcerans hypothetical protein 0.0022 0.0162 0.0307
Loa Loa (eye worm) hypothetical protein 0.0021 0.015 0.0146
Onchocerca volvulus 0.0184 0.175 0.1728
Brugia malayi isocitrate dehydrogenase 0.0019 0.0125 0.0121
Brugia malayi hypothetical protein 0.0009 0.0033 0.0029
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0094 0.0094
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0578 0.1134
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0011 0.0054 0.0407
Brugia malayi excitatory GABA receptor EXP-1A 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.0009 0.0026 0.0022
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi Endoplasmin precursor 0.0072 0.0645 0.0642
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0112
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0125 0.0746
Schistosoma mansoni transcription factor btf3 0.0021 0.0148 0.0298
Mycobacterium ulcerans hypothetical protein 0.0018 0.0116 0.0216
Trichomonas vaginalis DNA topoisomerase II, putative 0.0011 0.0054 0.0188
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Onchocerca volvulus 0.0015 0.0094 0.0068
Echinococcus granulosus apoptotic protease activating factor 1 0.0018 0.0119 0.0119
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0094 0.0189
Onchocerca volvulus 0.0012 0.0059 0.0033
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0011 0.0054 0.0407
Entamoeba histolytica heat shock protein 90, putative 0.0072 0.0645 0.3243
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0007 0.0009 0.0009
Brugia malayi MH2 domain containing protein 0.001 0.0036 0.0032
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.006 0.0533 0.0533
Brugia malayi neuropeptide F receptor 0.0015 0.0094 0.009
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0125 0.0249
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0014 0.008 0.0627
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.0036 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0059 0.0055
Schistosoma mansoni heat shock protein 0.0072 0.0645 0.1302
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0065 0.0497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Echinococcus multilocularis glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0125 0.0249
Brugia malayi Smad1 0.001 0.0036 0.0032
Brugia malayi larval opioid receptor 0.0015 0.0094 0.009
Onchocerca volvulus 0.0145 0.1367 0.1344
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0094 0.0189
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Brugia malayi intermediate filament protein 0.0039 0.0324 0.032
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0184 0.175 0.1746
Schistosoma mansoni cpg binding protein 0.0018 0.0121 0.0244
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0059 0.0059
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0116 0.0216
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0094 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0059 0.0055
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0011 0.0054 0.0094
Brugia malayi RE15519p 0.0015 0.0094 0.009
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0014 0.008 0.0145
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Plasmodium falciparum heat shock protein 90, putative 0.0038 0.0319 0.0634
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Loa Loa (eye worm) heat shock protein 75 0.0043 0.0363 0.0359
Echinococcus granulosus Smad4 0.001 0.0036 0.0036
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0094 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Brugia malayi Muscle positioning protein 4 0.0009 0.0026 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Toxoplasma gondii CAAX metallo endopeptidase 0.004 0.033 0.0655
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0094 0.0094
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0028 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0094 0.0094
Entamoeba histolytica acyl-CoA synthetase, putative 0.0018 0.0116 0.0583
Echinococcus multilocularis sex peptide receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis lamin 0.0039 0.0324 0.0324
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.015 0.0756
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0021 0.015 0.0303
Echinococcus granulosus ferritin 0.001 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0059 0.012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Echinococcus granulosus mothers against decapentaplegic 5 0.001 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Plasmodium falciparum DNA gyrase subunit B 0.0011 0.0054 0.0108
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0318 0.0641
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0088 0.0802 0.0798
Schistosoma mansoni hypothetical protein 0.006 0.053 0.1068
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0028 0.0214 0.0214
Schistosoma mansoni lamin 0.0039 0.0324 0.0653
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Mycobacterium ulcerans integral membrane protein 0.0022 0.0162 0.0307
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0125 0.0746
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis mothers against decapentaplegic 5 0.001 0.0036 0.0036
Echinococcus granulosus heat shock protein 0.0072 0.0645 0.0645
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0006 0.0004 0.0004
Trypanosoma cruzi PAB1-binding protein , putative 0.0015 0.009 0.0379
Trichomonas vaginalis heat shock protein, putative 0.0072 0.0645 0.2228
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0021 0.015 0.0303
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Onchocerca volvulus 0.0015 0.0094 0.0068
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0994 0.3432
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0009 0.0033 0.0029
Echinococcus granulosus lamin 0.0039 0.0324 0.0324
Schistosoma mansoni hypothetical protein 0.0009 0.0033 0.0066
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Echinococcus multilocularis cpg binding protein 0.0018 0.0121 0.0121
Schistosoma mansoni smad 0.001 0.0036 0.0073
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0094 0.0189
Trypanosoma cruzi Heat shock protein 83, putative 0.0072 0.0645 0.6211
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Brugia malayi Intermediate filament tail domain containing protein 0.0039 0.0324 0.032
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0094 0.0189
Echinococcus granulosus serotonin receptor 0.0015 0.0094 0.0094
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0209 0.199 1
Plasmodium vivax heat shock protein, putative 0.0209 0.1989 0.3947
Schistosoma mansoni hypothetical protein 0.0063 0.0562 0.1134
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi steroid hormone receptor 0.0012 0.0059 0.0055
Echinococcus multilocularis expressed protein 0.001 0.004 0.004
Brugia malayi exodeoxyribonuclease III family protein 0.0014 0.008 0.0076
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0094 0.0094
Brugia malayi Serotonin receptor 0.0015 0.0094 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Loa Loa (eye worm) latrophilin receptor protein 2 0.0028 0.0214 0.021
Entamoeba histolytica CAAX prenyl protease, putative 0.004 0.033 0.1658
Schistosoma mansoni farnesylated-protein converting enzyme 1 (M48 family) 0.004 0.033 0.0666
Onchocerca volvulus 0.0051 0.0438 0.0413
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.004 0.033 0.114
Schistosoma mansoni hypothetical protein 0.0015 0.0094 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0059 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Brugia malayi RNA binding protein 0.0129 0.1204 0.1201
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0059 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0009 0.0026 0.0022
Brugia malayi beta-NAC-like protein 0.0021 0.0148 0.0144
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Schistosoma mansoni hypothetical protein 0.0444 0.4294 0.8662
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0059 0.012
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0063 0.0562 0.0562
Brugia malayi G-protein coupled receptor 0.0015 0.0094 0.009
Brugia malayi G-protein coupled receptor 0.0015 0.0094 0.009
Echinococcus granulosus survival motor neuron protein 1 0.0248 0.2375 0.2375
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0039 0.0324 0.032
Brugia malayi Protein kinase domain containing protein 0.0009 0.0033 0.0029
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Echinococcus multilocularis ferritin 0.001 0.004 0.004
Onchocerca volvulus Huntingtin homolog 0.007 0.0632 0.0608
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Trypanosoma cruzi heat shock protein 90, putative 0.006 0.0533 0.5029
Brugia malayi GnHR receptor homolog 0.0015 0.0094 0.009
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0112
Loa Loa (eye worm) hypothetical protein 0.007 0.0632 0.0629
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0094 0.0094
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0011 0.0054 0.0094
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0094 0.0094
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.5037 1
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Mycobacterium leprae Probable two-component sensor kinase 0.0011 0.0054 0.0094
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0059 0.012
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0088 0.0802 0.0798
Mycobacterium tuberculosis Possible two component sensor kinase 0.0011 0.0054 0.0407
Loa Loa (eye worm) transcription factor SMAD2 0.0141 0.1328 0.1325
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0014 0.008 0.0269
Schistosoma mansoni ap endonuclease 0.0014 0.008 0.0161
Echinococcus multilocularis nAChR subunit 0.033 0.3175 0.3175
Plasmodium falciparum DNA topoisomerase 2 0.0011 0.0054 0.0108
Loa Loa (eye worm) MH2 domain-containing protein 0.0141 0.1328 0.1325
Brugia malayi Melatonin receptor type 1A 0.0015 0.0094 0.009
Brugia malayi heat shock protein 90 0.0072 0.0645 0.0642
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0094 0.009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0065 0.0497
Toxoplasma gondii CAAX amino terminal protease family protein 0.0022 0.0162 0.0321
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0028 0.0214 0.0214
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0011 0.0054 0.0028
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0094 0.0094
Entamoeba histolytica hypothetical protein 0.0063 0.0562 0.2826
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0184 0.175 0.3529
Loa Loa (eye worm) intermediate filament protein 0.0039 0.0324 0.032
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0125 0.0249
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0268 0.2244
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.0036 0.0032
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0094 0.0094
Giardia lamblia Heat shock protein HSP 90-alpha 0.0072 0.0645 0.3243
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0094 0.0094
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0059 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0094 0.009
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0094 0.0094
Echinococcus granulosus X box binding protein 1 0.0166 0.1565 0.1565
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0059 0.0033
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0011 0.0054 0.0407
Brugia malayi Cation transporter family protein 0.033 0.3175 0.3172
Treponema pallidum hypothetical protein 0.0022 0.0162 0.0244
Plasmodium vivax acyl-CoA synthetase, putative 0.0013 0.0072 0.0143
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0011 0.0054 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.009 0.0087
Trypanosoma cruzi heat shock protein 90, putative 0.0072 0.0645 0.6211
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0011 0.0054 0.0054
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.008 0.0276
Loa Loa (eye worm) ACC-1 protein 0.033 0.3175 0.3172
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0014 0.008 0.008
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0094 0.0189
Mycobacterium tuberculosis Bacterioferritin BfrB 0.001 0.004 0.028
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0116 0.0216
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.033 0.3175 0.3175
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0007 0.0009 0.0009
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0063 0.0562 0.0562
Toxoplasma gondii heat shock protein 75, putative 0.0043 0.0363 0.072
Echinococcus multilocularis glycine receptor subunit beta 0.033 0.3175 0.3175
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.5037 1
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.033 0.3175 0.3172
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0094 0.0094
Schistosoma mansoni opsin-like receptor 0.0015 0.0094 0.0189
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0094 0.0189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0318 0.0641
Echinococcus granulosus heat shock protein 90 0.0072 0.0645 0.0645
Echinococcus granulosus sex peptide receptor 0.0015 0.0094 0.0094
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0145 0.1367 0.1367
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0059 0.0525 0.2637
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.0125 0.1167 1
Trypanosoma cruzi heat shock protein 85, putative 0.0072 0.0645 0.6211
Echinococcus granulosus glycine receptor subunit beta 0.033 0.3175 0.3175
Echinococcus granulosus histone lysine methyltransferase setb 0.0038 0.0318 0.0318
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Plasmodium vivax heat shock protein 90, putative 0.0043 0.0363 0.072
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0011 0.0054 0.0094
Trypanosoma cruzi CAAX prenyl protease 1, putative 0.004 0.033 0.2897
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0094 0.0094
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0043 0.0363 0.0363
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0094 0.0094
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0059 0.0059
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0125 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0094 0.0094
Onchocerca volvulus 0.033 0.3175 0.3157
Toxoplasma gondii Hsp90 domain-containing protein 0.0209 0.1989 0.3947
Schistosoma mansoni ferritin light chain 0.001 0.004 0.008
Loa Loa (eye worm) TAR-binding protein 0.0129 0.1204 0.1201
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.015 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0148 0.0511
Schistosoma mansoni hypothetical protein 0.0444 0.4294 0.8662
Mycobacterium ulcerans heat shock protein 90 0.0065 0.0576 0.1131
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0059 0.0055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0042 0.0356 0.0356
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0059 0.0055
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0009 0.0033 0.0029
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0094 0.0094
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0438 0.0435
Entamoeba histolytica hypothetical protein 0.0063 0.0562 0.2826
Plasmodium vivax endoplasmin, putative 0.0072 0.0645 0.1281
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.009 0.018
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0125 0.0121
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0094 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0018 0.0119 0.0115
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0059 0.0059
Onchocerca volvulus 0.0145 0.1367 0.1344
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0094 0.009
Trypanosoma brucei CAAX amino terminal protease, putative 0.0109 0.1006 1
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.1026 1 1
Loa Loa (eye worm) RNA binding protein 0.0129 0.1204 0.1201
Mycobacterium ulcerans two component sensor kinase MprB 0.0011 0.0054 0.0094
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0094 0.0094
Schistosoma mansoni biogenic amine receptor 0.0015 0.0094 0.0189
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0065 0.0576 0.5483
Echinococcus granulosus tar DNA binding protein 0.0129 0.1204 0.1204
Onchocerca volvulus 0.0015 0.0094 0.0068
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni smad1 5 8 and 0.001 0.0036 0.0073
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0059 0.0059
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0512 0.4958 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Toxoplasma gondii heat shock protein HSP90 0.0072 0.0645 0.1281
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0011 0.0054 0.0094
Brugia malayi nuclear receptor NHR-88 0.0012 0.0059 0.0055
Plasmodium falciparum heat shock protein 90 0.0072 0.0645 0.1281
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0094 0.0094
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0042 0.0356 0.0356
Loa Loa (eye worm) TOPoisomerase family member 0.0011 0.0054 0.005
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.0356 0.0718
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0011 0.0054 0.0188
Echinococcus multilocularis caspase 2 0.0018 0.0119 0.0119
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0018 0.0116 0.0216
Brugia malayi Cation transporter family protein 0.033 0.3175 0.3172
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0059 0.012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.008 0.0159
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0994 0.3432
Trypanosoma brucei heat shock protein 90, putative 0.0072 0.0645 0.6211
Brugia malayi SEA domain containing protein 0.0009 0.0026 0.0022
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0094 0.0094
Echinococcus granulosus dnaJ subfamily B 0.0246 0.2352 0.2352
Echinococcus granulosus fmrfamide receptor 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0018 0.0119 0.0093
Echinococcus multilocularis glycine receptor subunit beta 0.033 0.3175 0.3175
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.033 0.3175 0.3172
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0042 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Echinococcus granulosus smad 0.001 0.0036 0.0036
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0014 0.008 0.0402
Onchocerca volvulus Putative nachr subunit 0.1026 1 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Plasmodium vivax protease, putative 0.0022 0.0162 0.0321
Schistosoma mansoni hypothetical protein 0.0009 0.0033 0.0066
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0013 0.0072 0.0558
Brugia malayi hypothetical protein 0.0015 0.009 0.0087
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0011 0.0054 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Brugia malayi hypothetical protein 0.007 0.0632 0.0629
Echinococcus multilocularis X box binding protein 1 0.0166 0.1565 0.1565
Trypanosoma brucei transcription factor BTF3, putative 0.0021 0.0148 0.0983
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.1367 0.1364
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0116 0.0937
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0145 0.1367 0.1367
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.0119 0.0239
Loa Loa (eye worm) hypothetical protein 0.0011 0.0054 0.005
Echinococcus granulosus orexin receptor type 2 0.0015 0.0094 0.0094
Giardia lamblia DNA repair protein RAD52 0.0209 0.199 1
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0054 0.0108
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0094 0.0189
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0065 0.0576 0.4903
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0094 0.009
Schistosoma mansoni apoferritin-2 0.001 0.004 0.008
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.033 0.3175 0.3175
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0094 0.0189
Schistosoma mansoni Smad4 0.001 0.0036 0.0073
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0054 0.005
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0011 0.0054 0.0094
Mycobacterium tuberculosis Conserved protein 0.0011 0.0054 0.0407
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0109 0.1006 0.3472
Echinococcus multilocularis smad 0.001 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Brugia malayi Hsp90 protein 0.0043 0.0363 0.0359
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0248 0.2375 0.2372
Trypanosoma brucei heat shock protein 90, putative 0.0072 0.0645 0.6211
Loa Loa (eye worm) heat shock protein 90 0.0072 0.0645 0.0642
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0094 0.0094
Schistosoma mansoni hypothetical protein 0.0028 0.0214 0.0432
Trypanosoma cruzi heat shock protein 85, putative 0.006 0.0533 0.5029
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Loa Loa (eye worm) hypothetical protein 0.006 0.053 0.0526
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.033 0.3175 0.3175
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.033 0.3175 0.3175
Brugia malayi nuclear hormone receptor 0.0012 0.0059 0.0055
Onchocerca volvulus 0.0015 0.0094 0.0068
Brugia malayi Cation transporter family protein 0.0512 0.4958 0.4956
Schistosoma mansoni DNA topoisomerase II 0.0011 0.0054 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0125 0.0125
Trypanosoma cruzi heat shock protein, putative 0.0043 0.0363 0.3239
Schistosoma mansoni hypothetical protein 0.0015 0.0094 0.0189
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0116 0.0647
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0019 0.0126 0.0126
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.1367 0.1364
Mycobacterium tuberculosis Probable integral membrane protein 0.0022 0.0162 0.1329
Schistosoma mansoni cpg binding protein 0.0017 0.0111 0.0224
Brugia malayi MH2 domain containing protein 0.001 0.0036 0.0032
Schistosoma mansoni ferritin 0.001 0.004 0.008
Schistosoma mansoni smad1 5 8 and 0.001 0.0036 0.0073
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0094 0.0094
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0014 0.008 0.0076
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0019 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0059 0.012
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0125 0.0746
Loa Loa (eye worm) GABA receptor subunit 0.0184 0.175 0.1746
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0043 0.0363 0.0337
Echinococcus granulosus GPCR family 2 0.0028 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.1026 1 1
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Brugia malayi ecdysteroid receptor 0.0012 0.0059 0.0055
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.015 0.1008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0125 0.0125
Echinococcus granulosus TGF beta signal transducer SmadC 0.001 0.0036 0.0036
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0059 0.0059
Brugia malayi G protein-coupled receptor 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0094 0.009
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0094 0.0094
Echinococcus multilocularis TGF beta signal transducer SmadC 0.001 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.007 0.0632 0.0629
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Mycobacterium ulcerans bacterioferritin BfrA 0.001 0.004 0.0065
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0042 0.0356 0.0352
Schistosoma mansoni survival motor neuron protein 0.0051 0.0438 0.0884
Echinococcus multilocularis transcription factor btf3 0.0021 0.0148 0.0148
Schistosoma mansoni acetylcholine receptor subunit beta 0.0145 0.1367 0.2758
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0512 0.4958 1
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0022 0.0162 0.1329
Onchocerca volvulus 0.033 0.3175 0.3157
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0059 0.0055
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0094 0.0189
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0028 0.0214 0.021
Brugia malayi Dopamine receptor protein 2 0.0015 0.0094 0.009
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0094 0.009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0038 0.0318 0.0318
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0578 0.1134
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0184 0.175 0.1746
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0011 0.0054 0.0188
Treponema pallidum exodeoxyribonuclease (exoA) 0.0014 0.008 0.0081
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0109 0.1006 1
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0011 0.0054 0.0094
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0011 0.0054 0.0029
Echinococcus granulosus ubiquitin specific protease 41 0.0021 0.015 0.015
Brugia malayi Dopamine receptor 0.0015 0.0094 0.009
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0109 0.1006 1
Onchocerca volvulus 0.0015 0.0094 0.0068
Echinococcus multilocularis serotonin receptor 0.0015 0.0094 0.0094
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0021 0.015 0.0756
Echinococcus multilocularis endoplasmin 0.0065 0.0576 0.0576
Brugia malayi TAR-binding protein 0.0129 0.1204 0.1201
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.0356 0.0718
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0155 0.1463 0.146
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0022 0.0162 0.1329
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0043 0.0363 0.1822
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Schistosoma mansoni ferritin 0.001 0.004 0.008
Onchocerca volvulus 0.0512 0.4958 0.4944
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Brugia malayi F/Y-rich N-terminus family protein 0.0007 0.0007 0.0003
Schistosoma mansoni hypothetical protein 0.0028 0.0214 0.0432
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0094 0.0189
Schistosoma mansoni endoplasmin 0.0072 0.0645 0.1302
Plasmodium vivax heat shock protein 86, putative 0.0072 0.0645 0.1281
Schistosoma mansoni coup transcription factor 0.0012 0.0059 0.012
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0094 0.0189
Schistosoma mansoni hypothetical protein 0.0166 0.1565 0.3157
Plasmodium vivax ataxin-2 like protein, putative 0.0015 0.009 0.018
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0116 0.0112
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0125 0.0746
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0094 0.0094
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0094 0.0094
Echinococcus multilocularis ubiquitin specific protease 41 0.0021 0.015 0.015
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0125 0.0253
Schistosoma mansoni hypothetical protein 0.0018 0.0119 0.0239
Echinococcus multilocularis MAM 0.0009 0.0033 0.0033
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0145 0.1367 0.1364
Echinococcus granulosus g protein coupled receptor 0.0015 0.0094 0.0094
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.033 0.3175 0.6404
Onchocerca volvulus 0.0015 0.0094 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.015 0.0519
Leishmania major hypothetical protein, conserved 0.0015 0.009 0.0379
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0011 0.0054 0.0188
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0059 0.012
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0094 0.009
Echinococcus granulosus neuropeptide receptor 0.0015 0.0094 0.0094
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0008 0.0008
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0094 0.009
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0043 0.0363 0.0363
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0145 0.1367 0.1364
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.033 0.3175 0.6404
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0148 0.0511
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Onchocerca volvulus Huntingtin homolog 0.007 0.0632 0.0608
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.033 0.3175 0.3175
Schistosoma mansoni pyruvate dehydrogenase 0.0011 0.0054 0.011
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.1026 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0119 0.0115
Giardia lamblia Grp94/Hsp90 0.0065 0.0576 0.2895
Echinococcus granulosus cpg binding protein 0.0018 0.0121 0.0121
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0014 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0112
Echinococcus granulosus CAAX prenyl protease 2 0.0109 0.1006 0.1006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0011 0.0054 0.0094
Echinococcus granulosus somatostatin receptor 0.0015 0.0094 0.0094
Brugia malayi Serotonin receptor 0.0015 0.0094 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0125 0.0249
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0011 0.0054 0.0108
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0011 0.0054 0.0407
Trypanosoma cruzi transcription factor btf3, putative 0.0021 0.0148 0.0983
Leishmania major CAAX prenyl protease 1, putative,metallo-peptidase, Clan M-, Family M48 0.004 0.033 0.2897
Loa Loa (eye worm) TK/ALK protein kinase 0.0009 0.0033 0.0029
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0011 0.0054 0.0054
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0094 0.0094
Leishmania major basic transcription factor 3a, putative 0.0021 0.0148 0.0983
Schistosoma mansoni hypothetical protein 0.0009 0.0026 0.0053
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.015 0.1008
Echinococcus multilocularis lamin dm0 0.0039 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0094 0.009
Echinococcus granulosus glycine receptor subunit beta 0.033 0.3175 0.3175
Echinococcus granulosus neuropeptide s receptor 0.0825 0.8027 0.8027
Loa Loa (eye worm) hypothetical protein 0.0038 0.0318 0.0314
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.033 0.3175 0.3172
Toxoplasma gondii heat shock protein 90, putative 0.0072 0.0645 0.1281
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0109 0.1006 0.2029
Echinococcus multilocularis heat shock protein 90 0.0072 0.0645 0.0645
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.001 0.004 0.028
Echinococcus granulosus geminin 0.0444 0.4294 0.4294
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.1026 1 1
Brugia malayi MH2 domain containing protein 0.0141 0.1328 0.1325
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0011 0.0054 0.0094
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Onchocerca volvulus 0.0015 0.0094 0.0068
Onchocerca volvulus 0.0038 0.0318 0.0292
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0059 0.0033
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0116 0.0216
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0094 0.0094
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.015 0.1008
Entamoeba histolytica hypothetical protein 0.0059 0.0525 0.2637
Echinococcus multilocularis tar DNA binding protein 0.0129 0.1204 0.1204
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0094 0.0094
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0578 0.1166
Loa Loa (eye worm) hypothetical protein 0.0039 0.0324 0.032
Brugia malayi Dopamine receptor protein 1 0.0015 0.0094 0.009
Plasmodium falciparum protease, putative 0.0022 0.0162 0.0321
Schistosoma mansoni opsin-like receptor 0.0015 0.0094 0.0189
Onchocerca volvulus 0.0015 0.0094 0.0068
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Entamoeba histolytica hypothetical protein 0.0063 0.0562 0.2826
Loa Loa (eye worm) ACC-1 protein 0.033 0.3175 0.3172
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0125 0.1018
Echinococcus granulosus nAChR subunit 0.0184 0.175 0.175
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0011 0.0054 0.0188
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0059 0.012
Entamoeba histolytica transcription factor BTF3, putative 0.0021 0.0148 0.0744
Schistosoma mansoni ferritin light chain 0.001 0.004 0.008
Echinococcus multilocularis glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Schistosoma mansoni myosin xvIII 0.0015 0.0094 0.0189
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0578 0.1147
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0184 0.175 0.1746
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Entamoeba histolytica hypothetical protein 0.0184 0.175 0.8792
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0148 0.0511
Trypanosoma brucei Heat shock protein 83, putative 0.0072 0.0645 0.6211
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0059 0.0055
Echinococcus multilocularis dnaJ subfamily B 0.0246 0.2352 0.2352
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.033 0.3175 0.3172
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0129 0.1204 0.1201
Brugia malayi neuropeptide F receptor 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus intermediate filament protein 0.0039 0.0324 0.0324
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0011 0.0054 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Trichomonas vaginalis heat shock protein, putative 0.0065 0.0576 0.1989
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0125 0.0746
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0094 0.0068
Chlamydia trachomatis hypothetical protein 0.0022 0.0162 0.0215
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0042 0.0356 0.0352
Echinococcus multilocularis somatostatin receptor 0.0015 0.0094 0.0094
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0028 0.0214 0.0214
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0021 0.015 0.015
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0145 0.1367 0.1367
Schistosoma mansoni neurotransmitter gated ion channel 0.0145 0.1367 0.2758
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Echinococcus granulosus caspase 2 0.0018 0.0119 0.0119
Loa Loa (eye worm) peptidase family M48 containing protein 0.004 0.033 0.0326
Schistosoma mansoni ferritin 0.001 0.004 0.008
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0011 0.0054 0.0407
Trypanosoma cruzi transcription factor btf3, putative 0.0021 0.0148 0.0983
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.033 0.3175 0.3175
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.001 0.004 0.0065
Onchocerca volvulus 0.0015 0.0094 0.0068
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.1367 0.1364
Leishmania major heat shock protein, putative 0.0043 0.0363 0.3239
Brugia malayi cytoplasmic intermediate filament protein 0.0021 0.0147 0.0143
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0011 0.0054 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Schistosoma mansoni transcription factor LCR-F1 0.0063 0.0562 0.1134
Brugia malayi STAT protein, DNA binding domain containing protein 0.0095 0.0872 0.0868
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0059 0.0055
Schistosoma mansoni nAChR subunit 0.0145 0.1367 0.2758
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0125 0.0125
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0094 0.009
Brugia malayi sulfakinin receptor protein 0.0015 0.0094 0.009
Echinococcus multilocularis CAAX prenyl protease 2 0.0109 0.1006 0.1006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0059 0.0055
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.015 0.1008
Loa Loa (eye worm) Smad1 0.001 0.0036 0.0032
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Brugia malayi putative neuropeptide receptor 0.0015 0.0094 0.009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0037 0.03 0.03
Toxoplasma gondii NAC domain-containing protein 0.0021 0.0148 0.0294
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Trichomonas vaginalis heat shock protein, putative 0.0065 0.0576 0.1989
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0145 0.1367 0.1367
Toxoplasma gondii histone lysine methyltransferase SET1 0.0034 0.0276 0.0548
Schistosoma mansoni hypothetical protein 0.0014 0.0082 0.0165
Onchocerca volvulus 0.0015 0.0094 0.0068
Schistosoma mansoni heat shock protein 0.0043 0.0363 0.0731
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0014 0.008 0.0269
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0011 0.0054 0.0108
Echinococcus granulosus g protein coupled receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.033 0.3175 0.3172
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0011 0.0054 0.0094
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Echinococcus granulosus caax prenyl protease 1 0.004 0.033 0.033
Plasmodium falciparum basic transcription factor 3b, putative 0.0021 0.0148 0.0294
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0578 0.0578
Loa Loa (eye worm) STAT protein 0.0095 0.0872 0.0868
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0011 0.0054 0.0029
Plasmodium vivax basic transcription factor 3b, putative 0.0021 0.0148 0.0294
Loa Loa (eye worm) hypothetical protein 0.0366 0.3533 0.353
Plasmodium falciparum heat shock protein 90, putative 0.0209 0.1989 0.3947
Loa Loa (eye worm) LGC-31 protein 0.033 0.3175 0.3172
Trypanosoma brucei PAB1-binding protein , putative 0.0015 0.009 0.0379
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.033 0.3175 0.3175
Brugia malayi CAAX amino terminal protease family protein 0.0109 0.1006 0.1002
Brugia malayi hypothetical protein 0.0248 0.2375 0.2372
Giardia lamblia Pms1-like protein 0.0011 0.0054 0.0274
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0094 0.0094
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0094 0.0094
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Trichomonas vaginalis receptor histidine kinase, putative 0.0011 0.0054 0.0188
Onchocerca volvulus 0.0039 0.0324 0.0298
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0038 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0512 0.4958 0.4944
Mycobacterium ulcerans two component regulator - sensor kinase 0.0011 0.0054 0.0094
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Loa Loa (eye worm) hypothetical protein 0.0018 0.0119 0.0115
Brugia malayi follicle stimulating hormone receptor 0.0015 0.0094 0.009
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0065 0.0576 0.1131
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0094 0.0094
Schistosoma mansoni biogenic amine receptor 0.0015 0.0094 0.0189
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0094 0.0094
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0009 0.0033 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0065 0.0497
Loa Loa (eye worm) hypothetical protein 0.0038 0.0317 0.0313
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0094 0.0189
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0578 0.1134
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0315 0.0634
Schistosoma mansoni neuropeptide receptor 0.0015 0.0094 0.0189
Loa Loa (eye worm) histone methyltransferase 0.0007 0.0008 0.0004
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis heat shock protein 0.0072 0.0645 0.0645
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0094 0.0094
Trichomonas vaginalis heat shock protein, putative 0.0038 0.0319 0.1103
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0011 0.0054 0.0054
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Entamoeba histolytica hypothetical protein 0.0063 0.0562 0.2826
Schistosoma mansoni acetylcholine receptor-related 0.0145 0.1367 0.2758
Echinococcus multilocularis apoptotic protease activating factor 1 0.0018 0.0119 0.0119
Schistosoma mansoni hypothetical protein 0.0015 0.0094 0.0189
Trypanosoma cruzi metallo- peptidase, Clan M- Family M48 0.004 0.033 0.2897
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0094 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Echinococcus granulosus heat shock protein 90 0.006 0.0533 0.0533
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0011 0.0054 0.0108
Schistosoma mansoni histamine h1 receptor 0.0015 0.0094 0.0189
Mycobacterium ulcerans hypothetical protein 0.0022 0.0162 0.0307
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.008 0.0159
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0125 0.0125
Onchocerca volvulus 0.0017 0.0111 0.0085
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0059 0.0059
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0018 0.0116 0.0216
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0011 0.0054 0.0407
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0094 0.0189
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0155 0.1463 0.146
Loa Loa (eye worm) DOMON domain-containing protein 0.0009 0.0026 0.0022
Onchocerca volvulus 0.0015 0.0094 0.0068
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.096 0.9356 0.9356
Trichomonas vaginalis heat shock protein, putative 0.006 0.0533 0.184
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.0242
Schistosoma mansoni cpg binding protein 0.0018 0.0121 0.0244
Trypanosoma cruzi PAB1-binding protein , putative 0.0015 0.009 0.0379
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.0356 0.0718
Echinococcus multilocularis heat shock protein 90 0.006 0.0533 0.0533
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0109 0.1006 1
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0059 0.0059
Brugia malayi kinase, mitochondrial precursor 0.0011 0.0054 0.005
Trichomonas vaginalis endoplasmin, putative 0.005 0.0432 0.1491
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.033 0.3175 0.3175
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0094 0.0189
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0059 0.0059
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0059 0.012
Onchocerca volvulus 0.0015 0.0094 0.0068
Loa Loa (eye worm) hypothetical protein 0.0028 0.0214 0.021
Echinococcus multilocularis nAChR subunit 0.0184 0.175 0.175
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0094 0.0094
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0578 0.5503
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0116 0.0112
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Entamoeba histolytica CAAX amino terminal protease family 0.0022 0.0162 0.0812
Schistosoma mansoni neuropeptide receptor 0.0015 0.0094 0.0189
Schistosoma mansoni intermediate filament proteins 0.0039 0.0324 0.0653
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0011 0.0054 0.0407
Loa Loa (eye worm) hypothetical protein 0.0512 0.4958 0.4956
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus hypothetical protein 0.0015 0.0094 0.0094
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0006 0.0004 0.0004
Onchocerca volvulus Glucosylceramidase homolog 0.0102 0.094 0.0916
Onchocerca volvulus 0.0015 0.0094 0.0068
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Trichomonas vaginalis ferritin, putative 0.001 0.004 0.0137
Echinococcus multilocularis GPCR, family 2 0.0028 0.0214 0.0214
Onchocerca volvulus 0.0018 0.0116 0.009
Toxoplasma gondii hypothetical protein 0.0022 0.0162 0.0321
Echinococcus granulosus glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0059 0.0055
Brugia malayi MH1 domain containing protein 0.001 0.0036 0.0032
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0059 0.0059
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0021 0.015 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Loa Loa (eye worm) hypothetical protein 0.0088 0.0802 0.0798
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0011 0.0054 0.0108
Mycobacterium tuberculosis Probable two component sensor kinase 0.0011 0.0054 0.0407
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0059 0.0055
Schistosoma mansoni hypothetical protein 0.0246 0.2352 0.4744
Schistosoma mansoni hypothetical protein 0.0007 0.0009 0.0017
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0094 0.0068
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0011 0.0054 0.0407
Treponema pallidum heat shock protein 90 0.0065 0.0576 0.1073
Brugia malayi AKH receptor 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0059 0.0055
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0021 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0122
Toxoplasma gondii hypothetical protein 0.0022 0.0162 0.0321
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Echinococcus granulosus expressed protein 0.001 0.004 0.004
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0011 0.0054 0.0094
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0094 0.0094
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0038 0.0318 0.063
Plasmodium vivax DNA topoisomerase II, putative 0.0011 0.0054 0.0108
Plasmodium vivax DNA gyrase subunit B, putative 0.0011 0.0054 0.0108
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0116 0.0647
Echinococcus multilocularis neuropeptide receptor A26 0.0825 0.8027 0.8027
Entamoeba histolytica CAAX prenyl protease family 0.0109 0.1006 0.5054
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0059 0.0059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0021 0.015 0.015
Schistosoma mansoni neuropeptide receptor 0.0015 0.0094 0.0189
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.1026 1 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0059 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0094 0.009
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0059 0.0059
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.033 0.3175 0.6404
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.004 0.033 0.114
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0059 0.0055
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0094 0.0189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0318 0.0641
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0059 0.012
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0116 0.0216
Brugia malayi Peptidase family M48 containing protein 0.004 0.033 0.0326
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni adenoreceptor 0.0015 0.0094 0.0189
Trypanosoma cruzi heat shock protein 85, putative 0.0072 0.0645 0.6211
Loa Loa (eye worm) hypothetical protein 0.0009 0.0033 0.0029
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0042 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0116 0.0216
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0011 0.0054 0.0028
Brugia malayi Cell death protein 3 precursor 0.0018 0.0119 0.0115
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0119 0.0115
Plasmodium falciparum acyl-CoA synthetase 0.0013 0.0072 0.0143
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0116 0.0112
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0125 0.0125
Schistosoma mansoni endoplasmin 0.0072 0.0645 0.1302
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0014 0.008 0.0402
Trichomonas vaginalis receptor histidine kinase, putative 0.0011 0.0054 0.0188
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Entamoeba histolytica acyl-CoA synthetase, putative 0.0018 0.0116 0.0583
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0094 0.009
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0011 0.0054 0.0054
Echinococcus multilocularis Smad4 0.001 0.0036 0.0036
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0125 0.0121
Onchocerca volvulus 0.0512 0.4958 0.4944
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0094 0.0189
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Onchocerca volvulus Cell death protein 3 homolog 0.0018 0.0119 0.0093
Entamoeba histolytica CAAX amino terminal protease family 0.0022 0.0162 0.0812
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0011 0.0054 0.0094
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0184 0.175 0.1746
Echinococcus granulosus neuropeptide receptor 0.0015 0.0094 0.0094
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.015 0.0519
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0145 0.1367 0.1364
Trypanosoma cruzi heat shock protein 85, putative 0.0072 0.0645 0.6211
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0094 0.009
Brugia malayi MH1 domain containing protein 0.001 0.0036 0.0032
Entamoeba histolytica hypothetical protein 0.0021 0.0148 0.0744
Onchocerca volvulus 0.033 0.3175 0.3157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0059 0.0055
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0578 0.4919
Schistosoma mansoni apoferritin-2 0.001 0.004 0.008
Trichomonas vaginalis sensor histidine kinase, putative 0.0011 0.0054 0.0188
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0109 0.1006 0.2029
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0094 0.0094
Echinococcus granulosus transcription factor btf3 0.0021 0.0148 0.0148
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0094 0.0189
Onchocerca volvulus 0.0039 0.0324 0.0298
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis caax prenyl protease 1 0.004 0.033 0.033
Brugia malayi hypothetical protein 0.001 0.0038 0.0034
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.1026 1 1
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Trypanosoma brucei heat shock protein 84, putative 0.0043 0.0363 0.3239
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0021 0.0147 0.0143
Loa Loa (eye worm) acetylcholine receptor protein 0.0145 0.1367 0.1364
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0011 0.0054 0.0094
Mycobacterium ulcerans putative regultory protein 0.0011 0.0054 0.0094
Brugia malayi hypothetical protein 0.0063 0.0562 0.0559
Schistosoma mansoni neurotransmitter gated ion channel 0.0184 0.175 0.3529
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0094 0.0189
Mycobacterium leprae Probable two component sensor kinase MprB 0.0011 0.0054 0.0094
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.052 0.5037 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0013 0.0072 0.0129
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.033 0.3175 0.3175
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.033 0.3175 0.3172
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis serotonin receptor 0.0015 0.0094 0.0094
Brugia malayi Calcitonin receptor-like protein seb-1 0.0088 0.0802 0.0798
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0059 0.012
Trichomonas vaginalis heat shock protein, putative 0.005 0.0432 0.1491
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0013 0.0072 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Trichomonas vaginalis set domain proteins, putative 0.0301 0.2896 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0059 0.0059
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0578 0.1166
Onchocerca volvulus 0.0301 0.2896 0.2878
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0018 0.0116 0.0216
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Entamoeba histolytica heat shock protein 90, putative 0.0072 0.0645 0.3243
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.001 0.004 0.0065
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0059 0.0055
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0011 0.0054 0.0188
Loa Loa (eye worm) hypothetical protein 0.0109 0.1006 0.1002
Mycobacterium ulcerans bacterioferritin BfrB 0.001 0.004 0.0065
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0094 0.0189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0059 0.0055
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0006 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.033 0.3175 0.3172
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.033 0.3175 0.3172
Echinococcus multilocularis survival motor neuron protein 1 0.0248 0.2375 0.2375
Echinococcus granulosus endoplasmin 0.0065 0.0576 0.0576
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.033 0.3175 0.3172
Onchocerca volvulus 0.0184 0.175 0.1728
Schistosoma mansoni nAChR subunit 0.0145 0.1367 0.2758
Echinococcus granulosus neuropeptide receptor A26 0.0825 0.8027 0.8027
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.008 0.0269
Loa Loa (eye worm) endoplasmin 0.0072 0.0645 0.0642
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Onchocerca volvulus 0.0015 0.0094 0.0068
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0065 0.0576 0.1131
Onchocerca volvulus 0.0015 0.0094 0.0068
Echinococcus multilocularis musashi 0.0039 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Trypanosoma brucei metallo- peptidase, Clan M- Family M48 0.004 0.033 0.2897
Schistosoma mansoni smad1 5 8 and 0.001 0.0036 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0059 0.0055
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Brugia malayi hypothetical protein 0.0018 0.0119 0.0115
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0014 0.008 0.0145
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Onchocerca volvulus 0.0009 0.0033 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0054 0.005
Entamoeba histolytica acyl-coA synthetase, putative 0.0018 0.0116 0.0583
Mycobacterium ulcerans DNA gyrase subunit B 0.0011 0.0054 0.0094
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0094 0.0094
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.0007 0.0007 0.0025
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0059 0.0055
Schistosoma mansoni biogenic amine receptor 0.0015 0.0094 0.0189
Echinococcus multilocularis neuropeptide s receptor 0.0825 0.8027 0.8027
Giardia lamblia Hypothetical protein 0.0109 0.1006 0.5054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Schistosoma mansoni lamin 0.0039 0.0324 0.0653
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0014 0.008 0.0269
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.033 0.3175 0.3172
Schistosoma mansoni hypothetical protein 0.0028 0.0214 0.0432
Toxoplasma gondii DNA topoisomerase 2, putative 0.0011 0.0054 0.0108
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0094 0.0094
Brugia malayi latrophilin 2 splice variant baaae 0.006 0.053 0.0526
Schistosoma mansoni hypothetical protein 0.0051 0.0438 0.0884
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0018 0.0116 0.0937
Schistosoma mansoni hypothetical protein 0.0028 0.0214 0.0432
Echinococcus multilocularis glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0094 0.0094
Brugia malayi ORL1-like opioid receptor 0.0015 0.0094 0.009
Echinococcus granulosus glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0059 0.0033
Schistosoma mansoni heat shock protein 0.0072 0.0645 0.1302
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Schistosoma mansoni ap endonuclease 0.0014 0.008 0.0161
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0038 0.0318 0.0641
Echinococcus multilocularis geminin 0.0444 0.4294 0.4294
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) ICD-1 protein 0.0021 0.0148 0.0144
Schistosoma mansoni neuropeptide receptor 0.0015 0.0094 0.0189
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0265 0.2538 0.2535
Plasmodium falciparum endoplasmin, putative 0.005 0.0432 0.0857
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.1026 1 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0162 0.1329
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.0036 0.0073
Loa Loa (eye worm) CXXC zinc finger family protein 0.0017 0.0111 0.0107
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.1026 1 1
Onchocerca volvulus 0.0015 0.0094 0.0068
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0011 0.0054 0.0407
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0011 0.0054 0.005
Plasmodium vivax SET domain protein, putative 0.0038 0.0318 0.063
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.0094 0.009
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.033 0.3175 0.3172
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0059 0.0059
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.009 0.018
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.015 0.0146
Brugia malayi CXXC zinc finger family protein 0.0017 0.0111 0.0107
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Onchocerca volvulus 0.0015 0.0094 0.0068
Echinococcus granulosus glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0512 0.4958 0.4956
Toxoplasma gondii exonuclease III APE 0.0014 0.008 0.0159
Echinococcus granulosus lamin dm0 0.0039 0.0324 0.0324
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.008 0.0276
Schistosoma mansoni hypothetical protein 0.0015 0.0094 0.0189
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi RNA recognition motif domain containing protein 0.0129 0.1204 0.1201
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0059 0.012

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = -5.62 Inhibitory concentration against DOXP reductoisomerase ChEMBL. 15887963

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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