Detailed information for compound 113289

Basic information

Technical information
  • TDR Targets ID: 113289
  • Name: disodium 4-[(4-amino-1-methylpyrrole-2-carbon yl)amino]naphthalene-1,7-disulfonate
  • MW: 469.4 | Formula: C16H13N3Na2O7S2
  • H donors: 2 H acceptors: 7 LogP: -0.27 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1cn(c(c1)C(=O)Nc1ccc(c2c1ccc(c2)S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+]
  • InChi: 1S/C16H15N3O7S2.2Na/c1-19-8-9(17)6-14(19)16(20)18-13-4-5-15(28(24,25)26)12-7-10(27(21,22)23)2-3-11(12)13;;/h2-8H,17H2,1H3,(H,18,20)(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2
  • InChiKey: GEJSZPYTUWHBIP-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

  • disodium 4-[(4-amino-1-methyl-pyrrole-2-carbonyl)amino]naphthalene-1,7-disulfonate
  • disodium 4-[[(4-amino-1-methyl-2-pyrrolyl)-oxomethyl]amino]naphthalene-1,7-disulfonate
  • disodium 4-[(4-azanyl-1-methyl-pyrrol-2-yl)carbonylamino]naphthalene-1,7-disulfonate
  • disodium 4-[(4-amino-1-methyl-pyrrol-2-yl)carbonylamino]naphthalene-1,7-disulfonate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Valyl-tRNA synthetase 0.0022 0.0061 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0395 0.0551
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0104 0.013
Leishmania major trypanothione reductase 0.0046 0.0351 0.0844
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0089 0.1106
Echinococcus granulosus Polycystic kidney disease protein 0.0057 0.0492 0.0913
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0081 0.0194
Plasmodium falciparum thioredoxin reductase 0.0046 0.0351 0.4923
Schistosoma mansoni coup transcription factor 0.0341 0.3983 0.5563
Onchocerca volvulus 0.0047 0.0362 0.0664
Echinococcus multilocularis lipoxygenase domain containing protein 0.0057 0.0492 0.0523
Echinococcus granulosus thyroid hormone receptor alpha 0.0161 0.1768 0.328
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0023 0.0043
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0061 0.0867
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0029 0.0241
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0089 0.1106
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0017 0.0022
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0351 0.4923
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0187 0.067
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0076
Loa Loa (eye worm) hypothetical protein 0.0341 0.3983 0.4965
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.018 0.2005 0.213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0187 0.067
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0074 0.0699 0.5768
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0043 0.0323 0.2907
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0058 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0023 0.0032
Brugia malayi Nuclear hormone receptor E75 0.0161 0.1768 0.1768
Brugia malayi nuclear hormone receptor family member odr-7 0.0161 0.1768 0.1768
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0229 0.0243
Entamoeba histolytica hypothetical protein 0.0035 0.0217 0.191
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0231 0.0288
Loa Loa (eye worm) hypothetical protein 0.018 0.2005 0.2499
Entamoeba histolytica hypothetical protein 0.0019 0.0017 0.004
Echinococcus granulosus intermediate filament protein 0.0026 0.011 0.0204
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0498 0.053
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0022 0.0061 0.0064
Loa Loa (eye worm) hypothetical protein 0.0341 0.3983 0.4965
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0856 0.1196
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0341 0.3983 0.3983
Echinococcus granulosus zinc finger protein 0.0019 0.0022 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0341 0.3983 0.3983
Schistosoma mansoni rab6-interacting 0.0057 0.0492 0.0687
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0573 0.1378
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.0083 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0017
Brugia malayi nuclear receptor NHR-88 0.0161 0.1768 0.1768
Loa Loa (eye worm) hypothetical protein 0.0048 0.0377 0.047
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0395 0.0732
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0341 0.3983 0.3983
Echinococcus granulosus histone lysine methyltransferase setb 0.0045 0.0347 0.0643
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0043 0.0323 0.0777
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0228 0.0549
Schistosoma mansoni ap endonuclease 0.0018 0.0013 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0341 0.3983 0.3983
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0138 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0061 0.0183
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.108 0.1147
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0013 0.0032
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.1213 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0017 0.0019
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0138 0.1826
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0017 0.0024
Schistosoma mansoni inositol monophosphatase 0.0036 0.0228 0.0319
Onchocerca volvulus 0.0026 0.011 0.0161
Onchocerca volvulus 0.0057 0.0492 0.0922
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0078 0.025
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0061 0.0085
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0104 0.025
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0389 0.0717
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0017 0.0024
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0061 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0323 0.1198
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0341 0.3983 0.4232
Loa Loa (eye worm) helicase 0.0022 0.0061 0.0076
Schistosoma mansoni lipoxygenase 0.0221 0.2499 0.3491
Schistosoma mansoni thyroid hormone receptor 0.06 0.716 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0012 0.0028
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0076
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0341 0.3983 0.4232
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0351 0.0373
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0243 0.0452
Loa Loa (eye worm) DR-78 0.0161 0.1768 0.2204
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0022 0.0061 0.0061
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0024
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0013 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0023 0.0032
Echinococcus granulosus lamin 0.0026 0.011 0.0204
Mycobacterium ulcerans hypothetical protein 0.0024 0.0081 0.0748
Loa Loa (eye worm) hypothetical protein 0.0048 0.0382 0.0476
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0341 0.3983 0.4965
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0061 0.0183
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.067 0.8022 1
Loa Loa (eye worm) hypothetical protein 0.018 0.2005 0.2499
Toxoplasma gondii thioredoxin reductase 0.0046 0.0351 0.5019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0076
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0228 0.0549
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0089 0.1274
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0389 0.1451
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0061 0.0183
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0081 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0341 0.3983 0.3983
Brugia malayi tailless protein 0.0161 0.1768 0.1768
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0022
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0017 0.0019
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0573 0.0573
Schistosoma mansoni chromobox protein 0.0078 0.0752 0.105
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0194 0.0194
Echinococcus multilocularis Protein lozenge 0.0054 0.0449 0.0477
Trypanosoma brucei protein kinase, putative 0.0049 0.0395 0.0949
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0699 1
Schistosoma mansoni lipoxygenase 0.0118 0.1236 0.1727
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0136 0.1944
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0395 0.0949
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0022
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0215 0.0516
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0074 0.0699 0.0699
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0187 0.067
Loa Loa (eye worm) phosphatidylinositol 3 0.0043 0.0323 0.0403
Entamoeba histolytica hypothetical protein 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0136 0.0169
Schistosoma mansoni nuclear hormone receptor 0.0341 0.3983 0.5563
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0215 0.0516
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0558 0.6643 0.8281
Plasmodium vivax SET domain protein, putative 0.0029 0.0144 0.191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0187 0.067
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0058 0.008
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0228 0.0549
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0061 0.0183
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.107 0.8822
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0229 0.032
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0341 0.3983 0.4232
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0017
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0104 0.013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0061 0.0183
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0019 0.0035
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0231 0.0323
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0022 0.0061 0.0867
Schistosoma mansoni ap endonuclease 0.0018 0.0013 0.0018
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.1213 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.0145 0.1576 0.1965
Loa Loa (eye worm) hypothetical protein 0.0341 0.3983 0.4965
Schistosoma mansoni chromobox protein 0.0078 0.0752 0.105
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.108 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0229 0.2022
Brugia malayi hypothetical protein 0.0158 0.1726 0.1726
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0138 0.1826
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0061 0.0691
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0259 0.2967 0.3153
Giardia lamblia GTOR 0.0043 0.0323 0.8129
Plasmodium vivax multidomain scavenger receptor, putative 0.0057 0.0492 0.6975
Brugia malayi hypothetical protein 0.0057 0.0492 0.0492
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0017 0.0024
Brugia malayi PXA domain containing protein 0.0019 0.0017 0.0017
Echinococcus granulosus lipoxygenase domain containing protein 0.0057 0.0492 0.0913
Echinococcus multilocularis Chromobox protein 3 0.0022 0.0061 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0214 0.0777
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0395 0.1474
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0022
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0231 0.0323
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0182 0.1504
Loa Loa (eye worm) hypothetical protein 0.018 0.2005 0.2499
Brugia malayi nuclear receptor NHR-88 0.0341 0.3983 0.3983
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0229 0.0425
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0228 0.0243
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0341 0.3983 0.3983
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0017 0.0032
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0017 0.0017
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0395 0.0419
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0347 0.0484
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0017 0.0032
Schistosoma mansoni hypothetical protein 0.0047 0.0362 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0341 0.3983 0.4965
Trichomonas vaginalis hypothetical protein 0.0022 0.0061 0.0183
Echinococcus granulosus Nuclear hormone receptor HR96 0.0161 0.1768 0.328
Loa Loa (eye worm) hypothetical protein 0.0048 0.0383 0.0478
Echinococcus granulosus chromobox protein 1 0.0078 0.0752 0.1395
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.018 0.2005 0.28
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0228 0.0831
Schistosoma mansoni steroid hormone receptor ad4bp 0.0341 0.3983 0.5563
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0083 0.0116
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.108 0.1346
Echinococcus granulosus Chromobox protein 3 0.0022 0.0061 0.0113
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.108 0.4122
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0221 0.2499 0.4638
Brugia malayi hypothetical protein 0.0109 0.1128 0.1128
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Mycobacterium tuberculosis Probable reductase 0.0104 0.107 0.8822
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0081 0.0194
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Plasmodium vivax glutathione reductase, putative 0.0046 0.0351 0.4923
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0043 0.0323 0.0777
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.108 0.1508
Brugia malayi 6-phosphofructokinase 0.0105 0.108 0.108
Schistosoma mansoni hypothetical protein 0.0259 0.2967 0.4144
Loa Loa (eye worm) hypothetical protein 0.0158 0.1726 0.2152
Echinococcus granulosus Chromo domain 0.0022 0.0061 0.0113
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0043 0.0323 0.0777
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0061 0.0445
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0022
Trichomonas vaginalis Heterochromatin protein, putative 0.0022 0.0061 0.0183
Echinococcus granulosus Nuclear hormone receptor HR96 0.0161 0.1768 0.328
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.2314 0.5564
Loa Loa (eye worm) hypothetical protein 0.0341 0.3983 0.4965
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0341 0.3983 0.4965
Brugia malayi Protein cec-1. 0.0022 0.0061 0.0061
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0395 0.0949
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0023 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0395 0.1474
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0144 0.0153
Schistosoma mansoni nuclear receptor 0.0161 0.1768 0.2469
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0138 0.1826
Onchocerca volvulus 0.0428 0.5045 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0028 0.0138 0.1175
Brugia malayi 6-phosphofructokinase 0.0105 0.108 0.108
Brugia malayi Cytochrome P450 family protein 0.0054 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0341 0.3983 0.4965
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0856 0.091
Loa Loa (eye worm) hypothetical protein 0.0341 0.3983 0.4965
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0061 0.0183
Schistosoma mansoni rab6-interacting 0.0057 0.0492 0.0687
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0341 0.3983 0.3983
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0023 0.0024
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0017 0.0019
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0856 0.1589
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0161 0.1768 0.328
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0228 0.0424
Echinococcus granulosus RUN 0.0057 0.0492 0.0913
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0061 0.0183
Entamoeba histolytica hypothetical protein 0.0019 0.0017 0.004
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.1213 1
Leishmania major hypothetical protein, conserved 0.0206 0.2314 0.5564
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Schistosoma mansoni jumonji domain containing protein 0.0073 0.069 0.0964
Brugia malayi jmjC domain containing protein 0.0092 0.0923 0.0923
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0078 0.025
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0074 0.0699 0.5768
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0138 0.1826
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0573 0.1378
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.539 0.5727
Onchocerca volvulus 0.0048 0.0377 0.0693
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0081 0.0748
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0061 0.0691
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0013 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0323 0.1198
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0395 1
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0017 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0106 0.0357
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0028 0.0138 0.198
Schistosoma mansoni retinoic acid receptor RXR 0.0437 0.5153 0.7196
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0341 0.3983 0.739
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0573 0.1378
Schistosoma mansoni bromodomain containing protein 0.0061 0.0541 0.0755
Loa Loa (eye worm) hypothetical protein 0.0024 0.0089 0.0111
Echinococcus multilocularis dna polymerase eta 0.0019 0.0019 0.002
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0209 0.0222
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0341 0.3983 0.5563
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0043 0.0323 0.0323
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0341 0.3983 0.3983
Leishmania major hypothetical protein, conserved 0.0024 0.0089 0.0214
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.108 0.1508
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0395 0.0949
Brugia malayi ecdysteroid receptor 0.0341 0.3983 0.3983
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0389 0.1451
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0243 0.0259
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0395 0.0419
Loa Loa (eye worm) runx1 0.0054 0.0449 0.056
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0395 0.1474
Trypanosoma brucei trypanothione reductase 0.0046 0.0351 0.0844
Plasmodium vivax heterochromatin protein 1, putative 0.0022 0.0061 0.0691
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0019 0.0019
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0104 0.025
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.0923 0.0981
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0161 0.1768 0.3466
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0341 0.3983 0.5563
Onchocerca volvulus 0.0026 0.011 0.0161
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0783 0.9411 1
Echinococcus multilocularis zinc finger protein 0.0019 0.0022 0.0024
Onchocerca volvulus 0.0051 0.0415 0.0769
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0214 0.0777
Echinococcus multilocularis lipoxygenase domain containing protein 0.0057 0.0492 0.0523
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0216 0.023
Schistosoma mansoni lamin 0.0026 0.011 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0229 0.0833
Brugia malayi SET domain containing protein 0.0023 0.0074 0.0074
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0228 0.0549
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0022
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0138 0.0484
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0019 0.0046
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0061 0.0445
Brugia malayi hypothetical protein 0.018 0.2005 0.2005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0076
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0039 0.0273 0.0341
Loa Loa (eye worm) hypothetical protein 0.0057 0.0492 0.0613
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0341 0.3983 0.5563
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0256 0.2938 0.3121
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0035 0.0043
Echinococcus granulosus ecdysone induced protein 78C 0.0341 0.3983 0.739
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0017 0.0017
Leishmania major DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Brugia malayi phosphofructokinase 0.0105 0.108 0.108
Loa Loa (eye worm) hypothetical protein 0.0651 0.7785 0.9704
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0017 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0061 0.0183
Brugia malayi ecdysone receptor 0.0161 0.1768 0.1768
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0214 0.0777
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0138 0.0484
Echinococcus granulosus chromobox protein 2 0.0022 0.0061 0.0113
Brugia malayi Cytochrome P450 family protein 0.0026 0.0104 0.0104
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0043 0.0323 0.0777
Echinococcus granulosus nuclear receptor nhr 48 0.0161 0.1768 0.328
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0019 0.0176
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0228 0.2017
Schistosoma mansoni hypothetical protein 0.0164 0.1801 0.2515
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0161 0.1768 0.2469
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.108 0.4122
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0138 0.0484
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0229 0.0833
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Schistosoma mansoni polycystin 1-related 0.0057 0.0492 0.0687
Echinococcus multilocularis lamin dm0 0.0026 0.011 0.0117
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0061 0.0085
Brugia malayi PAS domain containing protein 0.0047 0.0367 0.0367
Brugia malayi nuclear receptor NHR-67 0.0161 0.1768 0.1768
Loa Loa (eye worm) glutathione reductase 0.0046 0.0351 0.0438
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.2596 0.2758
Brugia malayi intermediate filament protein 0.0026 0.011 0.011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0341 0.3983 0.739
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.539 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0347 0.0432
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0078 0.025
Echinococcus granulosus dna polymerase kappa 0.0019 0.0019 0.0035
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0228 1
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.108 0.2596
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0017 0.0019
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0229 0.055
Onchocerca volvulus 0.0109 0.1127 0.2188
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0573 0.0715
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0362 0.0362
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0089 0.0214
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0019 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0187 0.067
Brugia malayi steroid hormone receptor 0.0341 0.3983 0.3983
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Brugia malayi conserved hypotetical protein 0.0161 0.1768 0.1768
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.0083 0.0089
Brugia malayi hypothetical protein 0.0019 0.0017 0.0017
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.0083 0.0104
Trichomonas vaginalis set domain proteins, putative 0.0229 0.2601 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0019 0.0024
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0017 0.0032
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0231 0.0429
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0089 0.0214
Echinococcus multilocularis nuclear receptor nhr 48 0.0161 0.1768 0.1878
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0187 0.067
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0217 0.0217
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0081 0.0261
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0341 0.3983 0.4965
Loa Loa (eye worm) hypothetical protein 0.0026 0.0104 0.013
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0043 0.0323 0.06
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0161 0.1768 0.1878
Loa Loa (eye worm) hypothetical protein 0.0037 0.0245 0.0306
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0042 0.0102
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0043 0.0323 0.0451
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0106 0.0357
Brugia malayi M-phase phosphoprotein, mpp8 0.0109 0.1127 0.1127
Brugia malayi PHD-finger family protein 0.0024 0.0086 0.0086
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0144 0.0201
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0341 0.3983 0.3983
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0367 0.0513
Schistosoma mansoni hypothetical protein 0.0022 0.0061 0.0085
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0017 0.0024
Schistosoma mansoni nuclear receptor nhr-48 0.0161 0.1768 0.2469
Onchocerca volvulus 0.0161 0.1768 0.3466
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0081 0.015
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0019 0.0027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Echinococcus multilocularis chromobox protein 2 0.0022 0.0061 0.0064
Brugia malayi Thioredoxin reductase 0.0046 0.0351 0.0351
Leishmania major C-8 sterol isomerase-like protein 0.0356 0.4159 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0382 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0078 0.0249
Schistosoma mansoni RAR-like nuclear receptor 0.0341 0.3983 0.5563
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0061 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0214 0.0777
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.107 0.8822
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0136 0.0252
Echinococcus granulosus dna polymerase eta 0.0019 0.0019 0.0035
Brugia malayi Heterochromatin protein 1 0.0078 0.0752 0.0752
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0081 0.0194
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0019 0.0046
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0341 0.3983 0.5563
Brugia malayi hypothetical protein 0.018 0.2005 0.2005
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0022 0.0061 0.0113
Loa Loa (eye worm) hypothetical protein 0.0341 0.3983 0.4965
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0019 0.0046
Schistosoma mansoni hypothetical protein 0.0035 0.0217 0.0303
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0341 0.3983 0.4965
Echinococcus multilocularis thyroid hormone receptor alpha 0.06 0.716 0.7608
Mycobacterium tuberculosis Conserved protein 0.0024 0.0081 0.0666
Echinococcus multilocularis FTZ F1 alpha 0.0341 0.3983 0.4232
Toxoplasma gondii phosphofructokinase PFKII 0.0028 0.0138 0.198
Loa Loa (eye worm) hypothetical protein 0.018 0.2005 0.2499
Brugia malayi Bromodomain containing protein 0.003 0.0164 0.0164
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0161 0.1768 0.2469
Brugia malayi hypothetical protein 0.0428 0.5045 0.5045
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0104 0.025
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0017 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0078 0.025
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0453 0.0564
Loa Loa (eye worm) hypothetical protein 0.0068 0.0629 0.0784
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0024
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0061 0.0445
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0013 0.0122
Entamoeba histolytica hypothetical protein 0.0035 0.0217 0.191
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0221 0.2499 0.2656
Brugia malayi PXA domain containing protein 0.0019 0.0017 0.0017
Leishmania major cytochrome p450-like protein 0.0026 0.0104 0.025
Loa Loa (eye worm) doublecortin family protein 0.0057 0.0492 0.0613
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0341 0.3983 0.4965
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0217 0.2012
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.107 0.8822
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0024
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.108 0.2596
Loa Loa (eye worm) hypothetical protein 0.003 0.0153 0.0191
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0019 0.0023
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.108 0.8904
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0022 0.0061 0.0691
Schistosoma mansoni zinc finger protein 0.0019 0.0022 0.0031
Loa Loa (eye worm) heterochromatin protein 1 0.0078 0.0752 0.0937
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0061 0.0183
Brugia malayi Pre-SET motif family protein 0.0201 0.2259 0.2259
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.108 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0428 0.5045 0.6289
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0118 0.0406
Brugia malayi nuclear receptor RXR 0.0161 0.1768 0.1768
Chlamydia trachomatis endonuclease IV 0.0074 0.0699 1
Plasmodium falciparum heterochromatin protein 1 0.0022 0.0061 0.0691
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0017 0.0019
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0081 0.0748
Echinococcus multilocularis RUN 0.0057 0.0492 0.0523
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0104 0.0963
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0061 0.0183
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0229 0.0425
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0019 0.0029 0.0029
Mycobacterium ulcerans hypothetical protein 0.0019 0.0029 0.0271
Echinococcus multilocularis expressed protein 0.0361 0.4219 0.4483
Brugia malayi Bromodomain containing protein 0.0072 0.068 0.068
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.0923 0.1713
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0699 1
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.108 1
Plasmodium falciparum phd finger protein, putative 0.0028 0.0136 0.1789
Echinococcus granulosus chromobox protein 1 0.0078 0.0752 0.1395
Brugia malayi hypothetical protein 0.0057 0.0492 0.0492
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0573 0.1378
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0036
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0229 0.0243
Loa Loa (eye worm) hypothetical protein 0.0428 0.5045 0.6289
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0377 0.0526
Brugia malayi hypothetical protein 0.0024 0.0089 0.0089
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0029 0.0241
Onchocerca volvulus 0.0057 0.0492 0.0922
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.107 0.8822
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0161 0.1768 0.1878
Brugia malayi Nuclear hormone receptor-like 1 0.067 0.8022 0.8022
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0061 0.0085
Brugia malayi Doublecortin family protein 0.0057 0.0492 0.0492
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0382 0.0382
Entamoeba histolytica hypothetical protein 0.0035 0.0217 0.191
Brugia malayi Inositol-1 0.0036 0.0228 0.0228
Brugia malayi nuclear hormone receptor 0.0161 0.1768 0.1768
Brugia malayi hypothetical protein 0.0228 0.2596 0.2596
Loa Loa (eye worm) phosphofructokinase 0.0105 0.108 0.1346
Onchocerca volvulus Bile acid receptor homolog 0.0341 0.3983 0.7882
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0028 0.0138 0.3285
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0017
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0382 0.0476
Echinococcus multilocularis peregrin 0.003 0.0164 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0109 0.0369
Loa Loa (eye worm) hypothetical protein 0.0074 0.0699 0.0872
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0229 0.5653
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0019 0.0019
Brugia malayi hypothetical protein 0.0161 0.1768 0.1768
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0024
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0017 0.0017
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0271 0.0504
Entamoeba histolytica hypothetical protein 0.0035 0.0217 0.191
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0341 0.3983 0.3983
Echinococcus granulosus neuropeptide s receptor 0.0456 0.539 1
Schistosoma mansoni chromobox protein 0.0022 0.0061 0.0085
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0217 0.0231
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.108 1
Brugia malayi hypoxia-induced factor 1 0.0145 0.1576 0.1576
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0017 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0061 0.0691
Schistosoma mansoni zinc finger protein 0.0161 0.1768 0.2469
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0341 0.3983 0.4232
Echinococcus multilocularis ecdysone induced protein 78C 0.0341 0.3983 0.4232
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0017 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0089 0.0214
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0259 0.2967 0.5505
Plasmodium falciparum LCCL domain-containing protein 0.0057 0.0492 0.6975
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0217 0.0303
Loa Loa (eye worm) hypothetical protein 0.0033 0.0194 0.0242
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0395 0.0949
Mycobacterium ulcerans epimerase 0.0019 0.0029 0.0271
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0061 0.0183
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0045 0.0347 0.0368
Schistosoma mansoni loxhd1 0.0057 0.0492 0.0687
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0341 0.3983 0.4965
Echinococcus granulosus expressed protein 0.0361 0.4219 0.7828
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0573 0.0609
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.107 0.8822
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0028 0.0138 0.0484
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.1213 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0492 0.0613
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.108 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0043 0.0323 0.0777
Echinococcus multilocularis lamin 0.0026 0.011 0.0117
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0341 0.3983 0.739
Loa Loa (eye worm) hypothetical protein 0.0036 0.0229 0.0285
Plasmodium falciparum glutathione reductase 0.0046 0.0351 0.4923
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0131 0.0243
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0041 0.0296 0.0369
Echinococcus granulosus single minded 2 0.0035 0.0217 0.0403
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0136 0.0475
Loa Loa (eye worm) inositol-1 0.0036 0.0228 0.0285
Echinococcus multilocularis chromobox protein 1 0.0078 0.0752 0.0799
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0023 0.0029
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0217 0.023
Onchocerca volvulus 0.0161 0.1768 0.3466
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0664 0.1232
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0347 0.0484
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0081 0.0666
Brugia malayi Nuclear hormone receptor E75 0.0161 0.1768 0.1768
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0341 0.3983 0.3983
Brugia malayi hypothetical protein 0.0019 0.0017 0.0017
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0229 0.0243
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0341 0.3983 0.739
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0228 0.0831
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0024
Brugia malayi PHD-finger family protein 0.0028 0.0136 0.0136
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0356 0.4159 1
Loa Loa (eye worm) hypothetical protein 0.0109 0.1127 0.1405
Brugia malayi jmjC domain containing protein 0.0036 0.0231 0.0231
Brugia malayi orphan nuclear receptor NR2E1 0.0161 0.1768 0.1768
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0504 0.0629
Brugia malayi hypothetical protein 0.0161 0.1768 0.1768
Brugia malayi nuclear hormone receptor 0.0341 0.3983 0.3983
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0573 0.1064
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0229 0.055
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0019 0.0046
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0017 0.0032
Brugia malayi chromobox protein homolog 3 0.0049 0.0389 0.0389
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0341 0.3983 0.739
Onchocerca volvulus 0.0035 0.0217 0.0375
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0395 0.0492
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0138 0.0484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0323 0.1198
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.108 0.2003
Brugia malayi Bromodomain containing protein 0.0037 0.0244 0.0244
Toxoplasma gondii exonuclease III APE 0.0018 0.0013 0.0189
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0341 0.3983 0.7882
Giardia lamblia PHD finger protein 15 0.0028 0.0136 0.3219
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0061 0.0183
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0081 0.0748
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.539 0.5727
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0228 0.2114
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0061 0.0183
Schistosoma mansoni DNA polymerase eta 0.0019 0.0019 0.0027
Loa Loa (eye worm) hypothetical protein 0.0182 0.2023 0.2522
Echinococcus granulosus lipoxygenase domain containing protein 0.0057 0.0492 0.0913
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.018 0.2005 0.372
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0023 0.0029
Echinococcus multilocularis Polycystic kidney disease protein 0.0057 0.0492 0.0523
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0341 0.3983 0.739
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0424 0.1587
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0013 0.0013
Mycobacterium ulcerans hypothetical protein 0.0024 0.0081 0.0748
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0182 0.1504
Loa Loa (eye worm) hypothetical protein 0.0356 0.4159 0.5184
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0752 0.2855
Schistosoma mansoni thyroid hormone receptor 0.06 0.716 1
Brugia malayi CHD4 protein 0.0024 0.0083 0.0083
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0395 0.0949
Loa Loa (eye worm) intermediate filament protein 0.0026 0.011 0.0137
Echinococcus granulosus geminin 0.0164 0.1801 0.3341
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0229 0.055
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0573 0.5251
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0341 0.3983 0.5563
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0351 0.0651
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0136 0.1789
Brugia malayi hypothetical protein 0.0035 0.0217 0.0217
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0089 0.1106
Onchocerca volvulus 0.0229 0.2602 0.5129
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0061 0.0183
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0395 0.0949
Schistosoma mansoni hypothetical protein 0.0164 0.1801 0.2515
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0017 0.0032
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0187 0.2668
Trypanosoma brucei hypothetical protein, conserved 0.0206 0.2314 0.5564
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0161 0.1768 0.328
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0217 0.0402
Schistosoma mansoni hypothetical protein 0.0057 0.0492 0.0687
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0229 0.0425
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0046
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.108 0.2596
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0341 0.3983 0.4232
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0229 0.0833
Schistosoma mansoni inositol monophosphatase 0.0036 0.0228 0.0319
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0573 0.0801
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0437 0.5153 0.956
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0013 0.0032
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.108 0.8904
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0161 0.1768 0.1768
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0664 0.0705
Schistosoma mansoni survival motor neuron protein 0.0047 0.0362 0.0506
Schistosoma mansoni nuclear hormone receptor 0.0161 0.1768 0.2469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0109 0.0369
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0023 0.0023
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.108 0.4122
Loa Loa (eye worm) nuclear receptor NHR-67 0.0161 0.1768 0.2204
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0043 0.0323 0.0777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0214 0.0777
Schistosoma mansoni nuclear receptor 0.0161 0.1768 0.2469
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0341 0.3983 0.4232
Loa Loa (eye worm) nuclear hormone receptor 0.0161 0.1768 0.2204
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0228 0.0831
Echinococcus granulosus peregrin 0.003 0.0164 0.0304
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0028 0.0138 0.1175
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0017 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0752 0.2855
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.011 0.011
Schistosoma mansoni lozenge 0.0054 0.0449 0.0628
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.107 0.8822
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0061 0.0867
Schistosoma mansoni hypothetical protein 0.0033 0.0194 0.0272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0341 0.3983 0.4965
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0271 0.0288
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0856 0.1196
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0161 0.1768 0.2204
Echinococcus granulosus lamin dm0 0.0026 0.011 0.0204
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0052 0.0424 0.0787
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0104 0.013
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0395 0.1474
Echinococcus multilocularis tumor protein p63 0.0326 0.3799 0.4037
Mycobacterium ulcerans endonuclease IV 0.0074 0.0699 0.6478
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0201 0.2259 0.2816
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0395 0.5642
Brugia malayi Associated with TFs and helicases family protein 0.0022 0.0061 0.0061
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0395 0.0732
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0215 0.0516
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0017 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0138 0.0484
Schistosoma mansoni lamin 0.0026 0.011 0.0154
Leishmania major DNA polymerase eta, putative 0.0019 0.0019 0.0046
Echinococcus multilocularis chromobox protein 1 0.0078 0.0752 0.0799
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0216 0.0401
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0351 0.0844
Schistosoma mansoni intermediate filament proteins 0.0026 0.011 0.0154
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0136 0.0144
Brugia malayi glutathione reductase 0.0046 0.0351 0.0351
Onchocerca volvulus 0.003 0.0153 0.0247
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0013 0.0014
Toxoplasma gondii 6-phosphofructokinase 0.0028 0.0138 0.198
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0043 0.0323 0.2907
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0424 0.1587
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.2314 0.5564
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0229 0.032
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0019 0.0157
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0043 0.0323 0.0343
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0136 0.0169
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0161 0.1768 0.2204
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0061 0.0183
Brugia malayi Pre-SET motif family protein 0.0029 0.0144 0.0144
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0061 0.0183
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0019 0.0029 0.0271
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0136 0.1944
Brugia malayi MAP kinase sur-1 0.0049 0.0395 0.0395
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0017 0.0024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0161 0.1768 0.1878
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0019 0.0046
Echinococcus multilocularis geminin 0.0164 0.1801 0.1913
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0019 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0109 0.0369
Loa Loa (eye worm) hypothetical protein 0.018 0.2005 0.2499
Echinococcus granulosus FTZ F1 alpha 0.0341 0.3983 0.739
Echinococcus multilocularis musashi 0.0026 0.011 0.0117
Brugia malayi nuclear hormone receptor family member nhr-6 0.0161 0.1768 0.1768
Schistosoma mansoni nuclear hormone receptor 0.0161 0.1768 0.2469
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0058 0.0107
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0061 0.0183
Brugia malayi Nuclear hormone receptor-like 1 0.067 0.8022 0.8022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0148 0.052
Onchocerca volvulus Protein ultraspiracle homolog 0.0341 0.3983 0.7882
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0017 0.0032
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0395 0.0949
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0341 0.3983 0.5563
Loa Loa (eye worm) hypothetical protein 0.0109 0.1128 0.1407
Loa Loa (eye worm) hypothetical protein 0.0228 0.2596 0.3236
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0341 0.3983 0.3983
Loa Loa (eye worm) hypothetical protein 0.0026 0.011 0.0137
Echinococcus granulosus tumor protein p63 0.0326 0.3799 0.7049
Onchocerca volvulus 0.0341 0.3983 0.7882
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0022 0.0061 0.0445
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.108 0.1346
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0019 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.0341 0.3983 0.3983
Entamoeba histolytica hypothetical protein 0.0022 0.0061 0.0445
Brugia malayi small heat shock protein 0.0558 0.6643 0.6643
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.2596 0.4816
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0078 0.0249
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0161 0.1768 0.1878
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0351 0.2895
Schistosoma mansoni chromobox protein 0.0022 0.0061 0.0085
Schistosoma mansoni retinoid-x-receptor (RXR) 0.018 0.2005 0.28
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0341 0.3983 0.3983
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0498 0.0925
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.011 0.0137
Onchocerca volvulus 0.0109 0.1127 0.2188
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.108 0.4122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0245 0.0897
Schistosoma mansoni hypothetical protein 0.0028 0.0136 0.019
Toxoplasma gondii endonuclease IV APN 0.0074 0.0699 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0228 0.3264
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0019 0.0027
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0013 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0061 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0118 0.0406
Giardia lamblia DINP protein human, muc B family 0.0019 0.0019 0.0153
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0356 0.4159 0.4159
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0351 0.0438
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0017 0.0019
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0013 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0078 0.0249
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0019 0.002
Entamoeba histolytica hypothetical protein 0.0022 0.0061 0.0445
Brugia malayi nuclear receptor RXR 0.018 0.2005 0.2005
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0051 0.0415 0.0579
Schistosoma mansoni hypothetical protein 0.002 0.0035 0.0049
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0017 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0187 0.067
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0229 0.055
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0076
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0136 0.019
Loa Loa (eye worm) steroid hormone receptor 0.0341 0.3983 0.4965
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0017 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0049 0.0389 0.0485
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0161 0.1768 0.3466
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0013 0.0032
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0019 0.0157
Echinococcus multilocularis Chromo domain 0.0022 0.0061 0.0064
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0017 0.0017
Trypanosoma brucei C-8 sterol isomerase, putative 0.0356 0.4159 1
Brugia malayi Cytochrome P450 family protein 0.0026 0.0104 0.0104
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0144 0.2062
Schistosoma mansoni single-minded 0.0047 0.0367 0.0513
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0017 0.0019
Onchocerca volvulus Alhambra homolog 0.0028 0.0136 0.0213
Brugia malayi photoreceptor-specific nuclear receptor 0.0341 0.3983 0.3983
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0019 0.0023
Trypanosoma brucei unspecified product 0.0019 0.0019 0.0046

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = -1 % The compound was tested for inhibition of Chemokine (RANTES) binding against C-C chemokine receptor type 5 transfected in HEK 293 cells ChEMBL. 9632350
Inhibition (binding) = -1 % The compound was tested for inhibition of Chemokine (RANTES) binding against C-C chemokine receptor type 5 transfected in HEK 293 cells ChEMBL. 9632350
Inhibition (binding) = 0.3 % The compound was tested for inhibition of Chemokine r (IL-8) binding against C-C chemokine receptor type 2 transfected in HEK 293 cells ChEMBL. 9632350
Inhibition (binding) = 0.3 % The compound was tested for inhibition of Chemokine r (IL-8) binding against C-C chemokine receptor type 2 transfected in HEK 293 cells ChEMBL. 9632350
Inhibition (binding) = 6.6 % The compound was tested for inhibition of Chemokine (MIP-1Beta) binding against C-C chemokine receptor type 5 transfected in HEK 293 cells ChEMBL. 9632350
Inhibition (binding) = 6.6 % The compound was tested for inhibition of Chemokine (MIP-1Beta) binding against C-C chemokine receptor type 5 transfected in HEK 293 cells ChEMBL. 9632350
Inhibition (binding) = 9.5 % The compound was tested for inhibition of Chemokine (MIP-1Alpha) binding against C-C chemokine receptor type 5 transfected in HEK 293 cells ChEMBL. 9632350
Inhibition (binding) = 9.5 % The compound was tested for inhibition of Chemokine (MIP-1Alpha) binding against C-C chemokine receptor type 5 transfected in HEK 293 cells ChEMBL. 9632350

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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