Detailed information for compound 1140899

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 683.348 | Formula: C17H28N5O18P3
  • H donors: 10 H acceptors: 15 LogP: -7.22 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC[C@H]1OC([C@H]([C@H]1O[C@@H]1OC(CO)[C@@H](C([C@@H]1O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)n1cnc2c1ncnc2NC
  • InChi: 1S/C17H28N5O18P3/c1-18-14-8-15(20-4-19-14)22(5-21-8)16-13(40-43(32,33)34)10(6(2-23)35-16)37-17-9(25)12(39-42(29,30)31)11(7(3-24)36-17)38-41(26,27)28/h4-7,9-13,16-17,23-25H,2-3H2,1H3,(H,18,19,20)(H2,26,27,28)(H2,29,30,31)(H2,32,33,34)/t6-,7?,9+,10+,11+,12?,13+,16?,17+/m1/s1
  • InChiKey: NVJNDWIEDDHVSM-OINZQXQFSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0294 0.0293
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0158
Trichomonas vaginalis D-aminoacylase, putative 0.0115 0.0596 0.2834
Brugia malayi Thioredoxin reductase 0.003 0.0026 0.0052
Onchocerca volvulus 0.0115 0.0596 0.5118
Loa Loa (eye worm) MBCTL1 0.0056 0.0198 0.0477
Echinococcus granulosus neuroligin 0.0036 0.0065 0.0064
Echinococcus multilocularis lamin 0.0057 0.0205 0.0204
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0151 0.0508
Schistosoma mansoni smad 0.003 0.0027 0.0026
Mycobacterium ulcerans esterase/lipase LipP 0.0115 0.0596 0.443
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.0104 0.0491
Echinococcus granulosus jumonji domain containing protein 0.0264 0.1603 0.1602
Echinococcus granulosus chromobox protein 1 0.0133 0.0719 0.0718
Mycobacterium ulcerans glutaminase 0.0225 0.1344 1
Schistosoma mansoni Smad4 0.003 0.0027 0.0026
Echinococcus multilocularis mothers against decapentaplegic 5 0.003 0.0027 0.0026
Trichomonas vaginalis chromobox protein, putative 0.0133 0.0719 0.3423
Echinococcus multilocularis snurportin 1 0.064 0.4147 0.4146
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0158
Echinococcus granulosus lamin dm0 0.0057 0.0205 0.0204
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0104 0.0491
Schistosoma mansoni phd/f-box containing protein 0.0095 0.0464 0.0463
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0053 0.0183 0.1352
Brugia malayi Bromodomain containing protein 0.0034 0.0049 0.0098
Schistosoma mansoni hypothetical protein 0.0037 0.007 0.0069
Echinococcus granulosus geminin 0.0823 0.5379 0.5378
Loa Loa (eye worm) hypothetical protein 0.0213 0.1261 0.304
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.012 0.0405
Entamoeba histolytica phosphofructokinase, putative 0.0086 0.0405 0.1924
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0994 0.4729
Mycobacterium tuberculosis Probable dehydrogenase 0.0069 0.0288 0.0552
Brugia malayi Melibiase family protein 0.007 0.0294 0.0603
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.015 0.0833 0.0832
Schistosoma mansoni smad1 5 8 and 0.003 0.0027 0.0026
Brugia malayi 6-phosphofructokinase 0.0086 0.0405 0.0829
Echinococcus granulosus lysosomal alpha glucosidase 0.0188 0.1092 0.1091
Mycobacterium tuberculosis Conserved protein 0.0115 0.0596 0.1202
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0213 0.1261 0.126
Trypanosoma brucei hypothetical protein, conserved 0.0115 0.0596 0.2017
Brugia malayi beta-lactamase family protein 0.0115 0.0596 0.1222
Trypanosoma brucei DNA polymerase beta thumb, putative 0.003 0.0028 0.0092
Trichomonas vaginalis esterase, putative 0.0115 0.0596 0.2834
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0073 0.0318 0.0317
Brugia malayi jmjC domain containing protein 0.0095 0.0464 0.095
Leishmania major hypothetical protein, conserved 0.0095 0.0464 0.1568
Brugia malayi follicle stimulating hormone receptor 0.0166 0.0945 0.1939
Mycobacterium tuberculosis Probable reductase 0.0069 0.0288 0.0552
Loa Loa (eye worm) hypothetical protein 0.0115 0.0596 0.1437
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0205 0.0494
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0192 0.1122 0.1121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.21 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0116 0.0606 0.1242
Brugia malayi Bromodomain containing protein 0.0192 0.1116 0.229
Mycobacterium tuberculosis Probable lipase LipD 0.0115 0.0596 0.1202
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.012 0.0405
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0086 0.0405 0.1369
Onchocerca volvulus 0.0166 0.0943 0.8464
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0073 0.0318 0.1073
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.022 0.0741
Loa Loa (eye worm) carboxylesterase 0.0213 0.1261 0.304
Echinococcus granulosus 6 phosphofructokinase 0.0086 0.0405 0.0404
Echinococcus granulosus snurportin 1 0.064 0.4147 0.4146
Echinococcus granulosus importin subunit beta 1 0.006 0.0227 0.0226
Trypanosoma brucei hypothetical protein, conserved 0.0463 0.295 1
Echinococcus granulosus acetylcholinesterase 0.0213 0.1261 0.126
Loa Loa (eye worm) acetylcholinesterase 1 0.0213 0.1261 0.304
Loa Loa (eye worm) hepatopoietin HPO2 0.0073 0.0318 0.0766
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0062 0.0241 0.1991
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0036 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0115 0.0596 0.1437
Echinococcus multilocularis chromobox protein 1 0.0133 0.0719 0.0718
Echinococcus granulosus JmjC domain containing protein 4 0.0095 0.0464 0.0463
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0151 0.0714
Echinococcus granulosus arachidonate 5 lipoxygenase 0.004 0.009 0.0089
Echinococcus granulosus PHD finger protein rhinoceros 0.0189 0.1102 0.1101
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0115 0.0596 0.1202
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0205 0.0419
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0103 0.0515 0.1743
Entamoeba histolytica phosphofructokinase, putative 0.0086 0.0405 0.1924
Loa Loa (eye worm) hypothetical protein 0.0359 0.2244 0.5412
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1607 0.7654
Brugia malayi intermediate filament protein 0.0057 0.0205 0.0419
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0037 0.0073 0.0245
Schistosoma mansoni ran 0.0044 0.012 0.0119
Echinococcus multilocularis carboxylesterase 5A 0.0213 0.1261 0.126
Loa Loa (eye worm) transcription factor SMAD2 0.0445 0.2827 0.6817
Trichomonas vaginalis chromobox protein, putative 0.008 0.0363 0.1727
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0082 0.0374 0.0373
Brugia malayi MH2 domain containing protein 0.003 0.0027 0.0053
Toxoplasma gondii ABC1 family protein 0.0115 0.0596 0.5403
Echinococcus multilocularis para nitrobenzyl esterase 0.0036 0.0065 0.0064
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0175 0.0422
Brugia malayi Carboxylesterase family protein 0.0036 0.0065 0.0132
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0105 0.053 0.0529
Brugia malayi Carboxylesterase family protein 0.0036 0.0065 0.0132
Echinococcus multilocularis Smad4 0.003 0.0027 0.0026
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0543 0.3487 0.3487
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.022 0.0219
Plasmodium vivax importin-beta 2, putative 0.006 0.0227 0.1869
Entamoeba histolytica Ran family GTPase 0.0044 0.012 0.0569
Schistosoma mansoni TGF-beta signal transducer Smad2 0.003 0.0027 0.0026
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0073 0.0318 0.2707
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0198 0.0404
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1607 0.7654
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.022 0.0219
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0158
Brugia malayi chromobox protein homolog 3 0.0074 0.0325 0.0666
Onchocerca volvulus Alhambra homolog 0.0189 0.1102 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0217 0.1286 0.4358
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0104 0.0491
Onchocerca volvulus Glucosylceramidase homolog 0.0173 0.0994 0.8955
Trichomonas vaginalis chromobox protein, putative 0.008 0.0363 0.1727
Leishmania major hypothetical protein, conserved 0.0463 0.295 1
Trypanosoma cruzi hypothetical protein, conserved 0.0463 0.295 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0115 0.0596 0.0595
Trichomonas vaginalis ran, putative 0.0044 0.012 0.0569
Loa Loa (eye worm) jmjC domain-containing protein 0.0358 0.2238 0.5398
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0158
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0152 0.0151
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0264 0.1607 0.33
Loa Loa (eye worm) hypothetical protein 0.0058 0.0217 0.0522
Brugia malayi RNA, U transporter 1 0.0171 0.0974 0.1999
Loa Loa (eye worm) hypothetical protein 0.0062 0.0241 0.058
Schistosoma mansoni ran 0.0044 0.012 0.0119
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.015 0.0833 0.0832
Schistosoma mansoni hypothetical protein 0.0823 0.5379 0.5378
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0104 0.0349
Schistosoma mansoni hypothetical protein 0.0823 0.5379 0.5378
Echinococcus multilocularis jumonji domain containing 1A 0.0095 0.0464 0.0463
Loa Loa (eye worm) hypothetical protein 0.0036 0.0063 0.0153
Schistosoma mansoni lamin 0.0057 0.0205 0.0204
Schistosoma mansoni bromodomain containing protein 0.0055 0.0197 0.0196
Loa Loa (eye worm) glutaminase 2 0.0225 0.1344 0.3241
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0053 0.0183 0.0616
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0031 0.0035 0.0034
Schistosoma mansoni alpha-glucosidase 0.0162 0.0915 0.0914
Toxoplasma gondii PHD-finger domain-containing protein 0.0189 0.1102 1
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0994 0.4729
Brugia malayi PHD-finger family protein 0.0189 0.1102 0.2261
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0152 0.0836
Schistosoma mansoni jumonji/arid domain-containing protein 0.0358 0.2238 0.2238
Loa Loa (eye worm) glutathione reductase 0.003 0.0026 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.21 1
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0062 0.0241 0.0812
Schistosoma mansoni BC026374 protein (S09 family) 0.0036 0.0065 0.0064
Schistosoma mansoni jumonji domain containing protein 0.0095 0.0464 0.0463
Loa Loa (eye worm) carboxylesterase 0.0036 0.0065 0.0158
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0053 0.0183 0.0616
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0198 0.0197
Entamoeba histolytica hypothetical protein 0.0082 0.0374 0.1775
Schistosoma mansoni hypothetical protein 0.0082 0.0374 0.0373
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0198 0.0197
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.022 0.1986
Echinococcus multilocularis importin subunit beta 1 0.006 0.0227 0.0226
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0027 0.0054
Echinococcus granulosus Smad4 0.003 0.0027 0.0026
Trypanosoma brucei trypanothione reductase 0.003 0.0026 0.0086
Toxoplasma gondii hypothetical protein 0.0035 0.0058 0.0522
Loa Loa (eye worm) MH2 domain-containing protein 0.003 0.0027 0.0065
Plasmodium vivax JmjC domain containing protein 0.0095 0.0464 0.4065
Brugia malayi MH1 domain containing protein 0.003 0.0027 0.0053
Brugia malayi glutathione reductase 0.003 0.0026 0.0052
Brugia malayi latrophilin 2 splice variant baaae 0.0079 0.0358 0.0733
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0105 0.053 0.0529
Loa Loa (eye worm) Smad1 0.003 0.0027 0.0065
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0188 0.1092 0.2633
Loa Loa (eye worm) hypothetical protein 0.0166 0.0943 0.2273
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0227 0.0768
Echinococcus granulosus intermediate filament protein 0.0057 0.0205 0.0204
Mycobacterium tuberculosis Probable oxidoreductase 0.0077 0.034 0.0662
Brugia malayi Bromodomain containing protein 0.0066 0.0266 0.0544
Trichomonas vaginalis phosphofructokinase, putative 0.0086 0.0405 0.1924
Schistosoma mansoni acetylcholinesterase 0.0036 0.0065 0.0064
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0543 0.3487 0.841
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0994 0.4729
Leishmania major ATP-dependent phosphofructokinase 0.0086 0.0405 0.1369
Treponema pallidum fructose-bisphosphate aldolase 0.0337 0.21 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0104 0.0491
Schistosoma mansoni jumonji domain containing protein 0.062 0.4008 0.4007
Brugia malayi Carboxylesterase family protein 0.0036 0.0065 0.0132
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0152 0.0151
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0115 0.0596 0.1202
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.022 0.0219
Loa Loa (eye worm) jmjC domain-containing protein 0.0095 0.0464 0.1118
Plasmodium falciparum JmjC domain-containing protein, putative 0.0095 0.0464 0.4065
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.064 0.4147 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0151 0.0714
Loa Loa (eye worm) hypothetical protein 0.0074 0.0325 0.0784
Toxoplasma gondii thioredoxin reductase 0.003 0.0026 0.0231
Entamoeba histolytica hypothetical protein 0.0082 0.0374 0.1775
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0086 0.0405 0.1369
Echinococcus multilocularis lamin dm0 0.0057 0.0205 0.0204
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1607 0.7654
Echinococcus multilocularis microtubule associated protein 2 0.1507 1 1
Echinococcus granulosus acetylcholinesterase 0.0213 0.1261 0.126
Brugia malayi mbt repeat family protein 0.0049 0.0152 0.031
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0158
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0165 0.0935 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0097 0.0475 0.0474
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0325 0.1545
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0337 0.21 1
Brugia malayi jmjC domain containing protein 0.0095 0.0464 0.095
Echinococcus multilocularis neuroligin 0.0036 0.0065 0.0064
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0115 0.0596 0.1222
Schistosoma mansoni hypothetical protein 0.0079 0.0358 0.0357
Giardia lamblia Fructose-bisphosphate aldolase 0.0337 0.21 1
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1057 0.503
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0198 0.0197
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.015 0.0833 0.0832
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0062 0.0241 0.0812
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0104 0.0491
Schistosoma mansoni hypothetical protein 0.0189 0.1102 0.1101
Echinococcus multilocularis peregrin 0.0192 0.1116 0.1115
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0543 0.3487 0.3487
Brugia malayi jmjC domain containing protein 0.0747 0.4869 1
Brugia malayi Carboxylesterase family protein 0.0213 0.1261 0.2588
Mycobacterium tuberculosis Probable esterase LipL 0.0115 0.0596 0.1202
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.21 1
Echinococcus multilocularis acetylcholinesterase 0.0213 0.1261 0.126
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0115 0.0596 0.0595
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0073 0.0318 0.1073
Brugia malayi glutaminase DH11.1 0.0225 0.1344 0.2758
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0103 0.0515 0.1743
Loa Loa (eye worm) hypothetical protein 0.0092 0.0447 0.1077
Trichomonas vaginalis D-aminoacylase, putative 0.0115 0.0596 0.2834
Schistosoma mansoni phosphatidylserine receptor 0.0095 0.0464 0.0463
Echinococcus granulosus lamin 0.0057 0.0205 0.0204
Schistosoma mansoni lipoxygenase 0.004 0.009 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0994 0.4729
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0115 0.0596 0.1437
Brugia malayi MH2 domain containing protein 0.003 0.0027 0.0053
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0747 0.4869 0.4869
Loa Loa (eye worm) hypothetical protein 0.0095 0.0464 0.1118
Trichomonas vaginalis phosphofructokinase, putative 0.0086 0.0405 0.1924
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0026 0.0086
Brugia malayi MH2 domain containing protein 0.0445 0.2827 0.5805
Loa Loa (eye worm) hypothetical protein 0.007 0.0294 0.071
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0036 0.0065 0.0064
Echinococcus granulosus neutral alpha glucosidase AB 0.0042 0.0104 0.0103
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.015 0.0833 0.0832
Echinococcus granulosus lysine specific demethylase 6a 0.0095 0.0464 0.0463
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0026 0.0001 0.5
Entamoeba histolytica hypothetical protein 0.0082 0.0374 0.1775
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0095 0.0464 0.1568
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0036 0.0065 0.0064
Brugia malayi beta-lactamase 0.0115 0.0596 0.1222
Loa Loa (eye worm) 6-phosphofructokinase 0.0086 0.0405 0.0976
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0994 0.4729
Schistosoma mansoni transcription factor LCR-F1 0.0082 0.0374 0.0373
Trypanosoma cruzi hypothetical protein, conserved 0.0463 0.295 1
Brugia malayi Carboxylesterase family protein 0.0036 0.0065 0.0132
Loa Loa (eye worm) hypothetical protein 0.0116 0.0606 0.146
Loa Loa (eye worm) hypothetical protein 0.0056 0.0198 0.0477
Echinococcus granulosus phd:f box containing protein 0.0095 0.0464 0.0463
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0198 0.0197
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.007 0.0294 0.1398
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0053 0.0183 0.0865
Schistosoma mansoni microtubule-associated protein tau 0.1507 1 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0213 0.1261 0.304
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.007 0.0142
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0152 0.0367
Mycobacterium leprae conserved hypothetical protein 0.0115 0.0596 0.476
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.21 1
Schistosoma mansoni intermediate filament proteins 0.0057 0.0205 0.0204
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0027 0.0066
Echinococcus multilocularis PHD finger protein rhinoceros 0.0189 0.1102 0.1101
Loa Loa (eye worm) hypothetical protein 0.0115 0.0596 0.1437
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0152 0.0151
Schistosoma mansoni alpha-glucosidase 0.0162 0.0915 0.0914
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.012 0.029
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0241 0.024
Mycobacterium ulcerans hypothetical protein 0.0115 0.0596 0.443
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0104 0.0491
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0077 0.034 0.0803
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0115 0.0596 0.0595
Echinococcus multilocularis smad 0.003 0.0027 0.0026
Loa Loa (eye worm) jmjC domain-containing protein 0.0391 0.2464 0.5943
Mycobacterium ulcerans hypothetical protein 0.0053 0.0183 0.1352
Echinococcus granulosus citrate lyase subunit beta protein 0.0053 0.0183 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0178 0.0845
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0069 0.0288 0.0552
Onchocerca volvulus 0.0058 0.0217 0.1459
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0152 0.0151
Plasmodium falciparum phd finger protein, putative 0.0189 0.1102 1
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0062 0.0241 0.2176
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0105 0.053 0.0529
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0152 0.0151
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0095 0.0464 0.4202
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0073 0.0318 0.1073
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0151 0.0714
Echinococcus granulosus lysine specific demethylase 5A 0.0358 0.2238 0.2238
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.007 0.0169
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0115 0.0596 0.443
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0596 0.2017
Loa Loa (eye worm) hypothetical protein 0.0115 0.0596 0.1437
Brugia malayi AF-10 protein 0.0062 0.0241 0.0492
Loa Loa (eye worm) inositol-1 0.0026 0.0001 0.0002
Mycobacterium tuberculosis Conserved protein 0.0115 0.0596 0.1202
Plasmodium falciparum importin beta, putative 0.006 0.0227 0.1869
Trichomonas vaginalis phosphofructokinase, putative 0.0086 0.0405 0.1924
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0052 0.0175 0.0174
Brugia malayi hypothetical protein 0.0166 0.0943 0.1934
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0086 0.0405 0.1807
Onchocerca volvulus 0.0049 0.0152 0.0836
Mycobacterium tuberculosis Conserved hypothetical protein 0.0114 0.0593 0.1197
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0596 0.2017
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0095 0.0464 0.1568
Leishmania major GTP-binding protein, putative 0.0044 0.012 0.0405
Brugia malayi F/Y-rich N-terminus family protein 0.0064 0.0252 0.0515
Echinococcus multilocularis neutral alpha glucosidase AB 0.0042 0.0104 0.0103
Loa Loa (eye worm) beta-lactamase 0.0115 0.0596 0.1437
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.012 0.0119
Loa Loa (eye worm) hypothetical protein 0.0092 0.0447 0.1077
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0104 0.0491
Loa Loa (eye worm) hypothetical protein 0.006 0.0227 0.0548
Echinococcus granulosus GPCR family 2 0.0037 0.007 0.0069
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0053 0.0183 0.1352
Trichomonas vaginalis spcc417.12 protein, putative 0.0036 0.0065 0.0307
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0205 0.0494
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0074 0.0325 0.2507
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0178 0.0845
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0052 0.0175 0.0174
Brugia malayi Augmenter of liver regeneration 0.0073 0.0318 0.065
Echinococcus granulosus peregrin 0.0192 0.1116 0.1115
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0037 0.007 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0325 0.1545
Brugia malayi jmjC domain containing protein 0.0095 0.0464 0.095
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0077 0.034 0.0662
Onchocerca volvulus Huntingtin homolog 0.0092 0.0447 0.3678
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0007 0.0006
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0069 0.0288 0.0552
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.004 0.009 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1607 0.7654
Brugia malayi Carboxylesterase family protein 0.0213 0.1261 0.2588
Schistosoma mansoni 6-phosphofructokinase 0.0086 0.0405 0.0404
Loa Loa (eye worm) hypothetical protein 0.0037 0.007 0.0169
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0165 0.0935 0.1917
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0053 0.0183 0.1352
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1607 0.7654
Schistosoma mansoni jumonji/arid domain-containing protein 0.0358 0.2238 0.2238
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.015 0.0833 0.1709
Echinococcus multilocularis lysosomal alpha glucosidase 0.0188 0.1092 0.1091
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.21 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0166 0.0945 0.2279
Echinococcus granulosus jumonji domain containing 1A 0.0095 0.0464 0.0463
Echinococcus multilocularis musashi 0.0057 0.0205 0.0204
Leishmania major mitochondrial DNA polymerase beta 0.0217 0.1286 0.4358
Loa Loa (eye worm) jmjC domain-containing protein 0.0095 0.0464 0.1118
Schistosoma mansoni 6-phosphofructokinase 0.0086 0.0405 0.0404
Loa Loa (eye worm) 6-phosphofructokinase 0.0086 0.0405 0.0976
Brugia malayi Calcitonin receptor-like protein seb-1 0.0116 0.0606 0.1242
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0042 0.0104 0.0936
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0294 0.0293
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0104 0.0491
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.21 1
Echinococcus granulosus chromobox protein 1 0.0133 0.0719 0.0718
Echinococcus multilocularis TGF beta signal transducer SmadC 0.003 0.0027 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0086 0.0405 0.1924
Plasmodium vivax hypothetical protein, conserved 0.0115 0.0596 0.5294
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1607 0.7654
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.0104 0.0212
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0053 0.0183 0.0616
Brugia malayi jmjC domain containing protein 0.0095 0.0464 0.095
Brugia malayi 6-phosphofructokinase 0.0086 0.0405 0.0829
Loa Loa (eye worm) MH2 domain-containing protein 0.0445 0.2827 0.6817
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0217 0.1286 0.4358
Trypanosoma brucei glucosidase, putative 0.0042 0.0104 0.0349
Schistosoma mansoni chromobox protein 0.0133 0.0719 0.0718
Schistosoma mansoni alpha glucosidase 0.0042 0.0104 0.0103
Echinococcus multilocularis acetylcholinesterase 0.0213 0.1261 0.126
Loa Loa (eye worm) phosphofructokinase 0.0086 0.0405 0.0976
Mycobacterium tuberculosis Carboxylesterase LipT 0.0036 0.0065 0.0082
Trichomonas vaginalis D-aminoacylase, putative 0.0115 0.0596 0.2834
Mycobacterium leprae Probable lipase LipE 0.0115 0.0596 0.476
Echinococcus granulosus beta LACTamase domain containing family member 0.0115 0.0596 0.0595
Schistosoma mansoni importin beta-1 0.006 0.0227 0.0226
Echinococcus multilocularis 6 phosphofructokinase 0.0086 0.0405 0.0404
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0073 0.0318 0.0317
Mycobacterium tuberculosis Conserved protein 0.0053 0.0183 0.033
Brugia malayi Importin beta-1 subunit 0.006 0.0227 0.0465
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.21 1
Loa Loa (eye worm) MH1 domain-containing protein 0.003 0.0027 0.0065
Toxoplasma gondii Erv1 / Alr family protein 0.0073 0.0318 0.2875
Onchocerca volvulus Huntingtin homolog 0.0092 0.0447 0.3678
Brugia malayi indoleamine 2,3-dioxygenase 0.0543 0.3487 0.7161
Loa Loa (eye worm) hypothetical protein 0.0034 0.0049 0.0119
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0105 0.053 0.0529
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0994 0.4729
Toxoplasma gondii melibiase subfamily protein 0.0105 0.053 0.4808
Leishmania major alpha glucosidase II subunit, putative 0.0042 0.0104 0.0349
Trichomonas vaginalis chromobox protein, putative 0.0133 0.0719 0.3423
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0007 0.0006
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0042 0.0104 0.0251
Trichomonas vaginalis penicillin-binding protein, putative 0.0115 0.0596 0.2834
Brugia malayi hypothetical protein 0.0082 0.0374 0.0765
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.003 0.0028 0.0092
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0152 0.0151
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.012 0.0245
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.015 0.0833 0.2008
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.022 0.0219
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0227 0.0768
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0732 0.4764 1
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0198 0.0197
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.022 0.1628
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0073 0.0318 0.2707
Echinococcus multilocularis lysine specific demethylase 6a 0.0095 0.0464 0.0463
Echinococcus granulosus para nitrobenzyl esterase 0.0036 0.0065 0.0064
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.012 0.0874
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0189 0.1102 0.1101
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0105 0.053 0.0529
Schistosoma mansoni hypothetical protein 0.0037 0.007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0056 0.0198 0.0477
Schistosoma mansoni hypothetical protein 0.0037 0.007 0.0069
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.007 0.0069
Entamoeba histolytica hypothetical protein 0.0049 0.0151 0.0714
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0104 0.0491
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0241 0.1991
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0036 0.0065 0.0064
Brugia malayi hypothetical protein 0.0036 0.0065 0.0132
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0116 0.0606 0.146
Schistosoma mansoni hypothetical protein 0.064 0.4147 0.4146
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.012 0.0119
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0241 0.2176
Schistosoma mansoni glutaminase 0.0225 0.1344 0.1343
Echinococcus multilocularis phd:f box containing protein 0.0095 0.0464 0.0463
Leishmania major hypothetical protein, conserved 0.0073 0.0318 0.1073
Entamoeba histolytica phosphofructokinase, putative 0.0086 0.0405 0.1924
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0082 0.0374 0.0373
Echinococcus multilocularis lysine specific demethylase 5A 0.0356 0.2227 0.2226
Schistosoma mansoni hypothetical protein 0.0297 0.1827 0.1826
Loa Loa (eye worm) glutaminase 0.0225 0.1344 0.3241
Entamoeba histolytica hypothetical protein 0.0082 0.0374 0.1775
Echinococcus multilocularis geminin 0.0823 0.5379 0.5378
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0105 0.053 0.0529
Brugia malayi jmjC domain containing protein 0.0358 0.2238 0.4596
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.018
Brugia malayi MH1 domain containing protein 0.003 0.0027 0.0053
Schistosoma mansoni neuroligin 3 (S09 family) 0.0036 0.0065 0.0064
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.007 0.0069
Echinococcus granulosus TGF beta signal transducer SmadC 0.003 0.0027 0.0026
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.012 0.0405
Loa Loa (eye worm) PHD-finger family protein 0.0189 0.1102 0.2657
Loa Loa (eye worm) thioredoxin reductase 0.003 0.0026 0.0064
Brugia malayi mbt repeat family protein 0.0049 0.0152 0.031
Toxoplasma gondii PHD-finger domain-containing protein 0.0189 0.1102 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0464 0.1118
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.022 0.0408
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0069 0.0288 0.0552
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.012 0.0874
Schistosoma mansoni smad1 5 8 and 0.003 0.0027 0.0026
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.015 0.0833 0.0832
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0036 0.0065 0.0082
Mycobacterium ulcerans lipase LipD 0.0115 0.0596 0.443
Trichomonas vaginalis glutaminase, putative 0.0225 0.1344 0.6398
Schistosoma mansoni lamin 0.0057 0.0205 0.0204
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0264 0.1607 0.3876
Echinococcus multilocularis jumonji domain containing protein 0.0264 0.1603 0.1602
Loa Loa (eye worm) hypothetical protein 0.0115 0.0596 0.1437
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0994 0.4729
Echinococcus multilocularis lysosomal alpha glucosidase 0.0188 0.1092 0.1091
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0073 0.0318 0.1073
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0036 0.0065 0.0082
Echinococcus multilocularis chromobox protein 1 0.0133 0.0719 0.0718
Echinococcus multilocularis JmjC domain containing protein 4 0.0095 0.0464 0.0463
Giardia lamblia PHD finger protein 15 0.0189 0.1102 0.4959
Leishmania major trypanothione reductase 0.003 0.0026 0.0086
Echinococcus granulosus mothers against decapentaplegic 5 0.003 0.0027 0.0026
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0152 0.0151
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0747 0.4869 0.4869
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.022 0.1628
Brugia malayi PHD-finger family protein 0.0064 0.0252 0.0515
Echinococcus granulosus smad 0.003 0.0027 0.0026
Mycobacterium tuberculosis Conserved protein 0.0115 0.0596 0.1202
Loa Loa (eye worm) hypothetical protein 0.0079 0.0358 0.0863
Echinococcus granulosus thioredoxin glutathione reductase 0.003 0.0026 0.0025
Echinococcus granulosus carboxylesterase 5A 0.0213 0.1261 0.126
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0158
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0077 0.034 0.0662
Loa Loa (eye worm) hypothetical protein 0.0115 0.0596 0.1437
Onchocerca volvulus 0.0109 0.0557 0.4739
Onchocerca volvulus 0.0115 0.0596 0.5118
Onchocerca volvulus 0.0115 0.0596 0.5118
Loa Loa (eye worm) hypothetical protein 0.0064 0.0252 0.0607
Trichomonas vaginalis sucrase-isomaltase, putative 0.0042 0.0104 0.0491
Schistosoma mansoni hypothetical protein 0.0543 0.3487 0.3487
Schistosoma mansoni gliotactin 0.0036 0.0065 0.0064
Onchocerca volvulus 0.0057 0.0205 0.1347
Loa Loa (eye worm) hypothetical protein 0.0057 0.0205 0.0494
Leishmania major importin beta-1 subunit, putative 0.0049 0.0151 0.0508
Mycobacterium tuberculosis Probable hydrolase 0.0115 0.0596 0.1202
Loa Loa (eye worm) hypothetical protein 0.0189 0.1102 0.2657
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0104 0.0491
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0158
Mycobacterium ulcerans hypothetical protein 0.0114 0.0593 0.4412
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.003 0.0028 0.0092
Echinococcus multilocularis citrate lyase subunit beta protein 0.0053 0.0183 0.0182
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0053 0.0183 0.033
Schistosoma mansoni chromobox protein 0.0133 0.0719 0.0718
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0217 0.1286 0.4358
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0037 0.007 0.0069
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0095 0.0464 0.4202
Schistosoma mansoni hypothetical protein 0.0062 0.0241 0.024
Brugia malayi hypothetical protein 0.0092 0.0447 0.0915
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0103 0.0515 0.1743
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0095 0.0464 0.0463
Plasmodium vivax hypothetical protein, conserved 0.0189 0.1102 1
Schistosoma mansoni hypothetical protein 0.0037 0.007 0.0069
Onchocerca volvulus 0.0057 0.0205 0.1347
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0115 0.0596 0.1202
Schistosoma mansoni hypothetical protein 0.0543 0.3487 0.3487
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.012 0.1085
Trichomonas vaginalis penicillin-binding protein, putative 0.0115 0.0596 0.2834
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0031 0.0035 0.0034
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.003 0.0028 0.0092
Leishmania major hypothetical protein, conserved 0.0115 0.0596 0.2017
Loa Loa (eye worm) hypothetical protein 0.0049 0.0152 0.0367
Echinococcus multilocularis GPCR, family 2 0.0037 0.007 0.0069
Schistosoma mansoni protein phosphatase 2C 0.0095 0.0464 0.0463
Echinococcus multilocularis BC026374 protein (S09 family) 0.0036 0.0065 0.0064
Brugia malayi Latrophilin receptor protein 2 0.0037 0.007 0.0142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.21 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0192 0.1122 0.1121
Schistosoma mansoni smad1 5 8 and 0.003 0.0027 0.0026
Toxoplasma gondii HEAT repeat-containing protein 0.006 0.0227 0.2056
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0104 0.0349
Brugia malayi phosphofructokinase 0.0086 0.0405 0.0829
Brugia malayi Heterochromatin protein 1 0.0133 0.0719 0.1476
Toxoplasma gondii Erv1 / Alr family protein 0.0073 0.0318 0.2875
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0036 0.0065 0.0307
Echinococcus granulosus BC026374 protein S09 family 0.0036 0.0065 0.0064
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.022 0.1628
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0036 0.0065 0.0064
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0069 0.0288 0.0552
Brugia malayi beta-lactamase family protein 0.0115 0.0596 0.1222
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1057 0.503
Onchocerca volvulus Heterochromatin protein 1 homolog 0.008 0.0363 0.2875
Brugia malayi Glycosyl hydrolases family 31 protein 0.0188 0.1092 0.2241
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0086 0.0405 0.0799
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.015 0.0833 0.0832
Mycobacterium ulcerans carboxylesterase, LipT 0.0036 0.0065 0.0479
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0095 0.0464 0.1568
Mycobacterium ulcerans 6-phosphofructokinase 0.0086 0.0405 0.3007
Loa Loa (eye worm) carboxylesterase 0.0036 0.0065 0.0158
Loa Loa (eye worm) heterochromatin protein 1 0.0133 0.0719 0.1735
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0105 0.053 0.0529
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0337 0.21 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0095 0.0464 0.1118
Mycobacterium ulcerans beta-lactamase 0.0115 0.0596 0.443
Echinococcus multilocularis thioredoxin glutathione reductase 0.003 0.0026 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.015 0.0833 0.0832
Mycobacterium tuberculosis Probable lipase LipE 0.0115 0.0596 0.1202
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0165 0.0935 0.6954
Mycobacterium ulcerans hypothetical protein 0.0053 0.0183 0.1352
Brugia malayi Cytochrome P450 family protein 0.0052 0.0175 0.0357
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0097 0.0475 0.0474
Brugia malayi Smad1 0.003 0.0027 0.0053

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.