Detailed information for compound 1349280

Basic information

Technical information
  • TDR Targets ID: 1349280
  • Name: 3-(imidazol-1-ylmethyl)pyridine
  • MW: 159.188 | Formula: C9H9N3
  • H donors: 0 H acceptors: 2 LogP: 0.54 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc(cn1)Cn1cncc1
  • InChi: 1S/C9H9N3/c1-2-9(6-10-3-1)7-12-5-4-11-8-12/h1-6,8H,7H2
  • InChiKey: IRLWEKCRDMFHQW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(1-imidazolylmethyl)pyridine
  • MLS-0091918.0001

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cytochrome P450, family 11, subfamily B, polypeptide 2 Starlite/ChEMBL References
Homo sapiens cytochrome P450, family 11, subfamily B, polypeptide 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Toxoplasma gondii cytochrome p450 superfamily protein Get druggable targets OG5_134469 All targets in OG5_134469
Neospora caninum Os02g0824100 protein, related Get druggable targets OG5_134469 All targets in OG5_134469
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.004 0.0132 0.0339
Echinococcus multilocularis mitogen activated protein kinase 3 0.0068 0.0446 0.1142
Trypanosoma cruzi casein kinase, putative 0.0055 0.0302 0.0972
Schistosoma mansoni tyrosine kinase 0.0039 0.0127 0.0325
Brugia malayi map kinase activated protein kinase protein 2 0.0382 0.3902 0.3902
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0057 0.0326 0.0721
Schistosoma mansoni protein kinase 0.0191 0.1794 0.4596
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0114 0.0946 0.0907
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0104 0.0836 0.1851
Brugia malayi Furin-like cysteine rich region family protein 0.0227 0.2192 0.2192
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0055 0.0302 0.0301
Echinococcus granulosus titin 0.003 0.0027 0.0058
Loa Loa (eye worm) hypothetical protein 0.0033 0.0058 0.0057
Echinococcus multilocularis epidermal growth factor receptor 0.0227 0.2192 0.5618
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Loa Loa (eye worm) hypothetical protein 0.0175 0.1621 0.162
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0326 0.0835
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1133 0.4195
Brugia malayi Protein kinase domain containing protein 0.0028 0.0004 0.0003
Loa Loa (eye worm) TK protein kinase 0.0128 0.11 0.11
Giardia lamblia Kinase, PLK 0.0257 0.2522 1
Entamoeba histolytica protein kinase, putative 0.0131 0.1133 0.4466
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0257 0.2522 0.2522
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0069 0.0456 0.1599
Loa Loa (eye worm) hypothetical protein 0.0082 0.0604 0.0603
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0142 0.1257 0.2785
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.035 0.0896
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0144 0.1285 0.4949
Trichomonas vaginalis AGC family protein kinase 0.0066 0.042 0.1239
Loa Loa (eye worm) hypothetical protein 0.014 0.124 0.1239
Trichomonas vaginalis AGC family protein kinase 0.0258 0.2533 1
Schistosoma mansoni protein kinase 0.0049 0.0229 0.0588
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0068 0.0446 0.0393
Giardia lamblia Kinase, CMGC GSK 0.0114 0.0946 0.3406
Toxoplasma gondii aurora kinase 0.0131 0.1133 0.1099
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0039 0.0127 0.0325
Onchocerca volvulus 0.0036 0.009 0.0249
Brugia malayi Protein kinase domain containing protein 0.0258 0.2533 0.2532
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0057 0.0326 0.1071
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0131 0.1133 0.2904
Loa Loa (eye worm) hypothetical protein 0.0071 0.0472 0.0471
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.004 0.0132 0.0131
Echinococcus multilocularis serine:threonine protein kinase 38 0.0128 0.111 0.2844
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Echinococcus granulosus twitchin 0.0077 0.0538 0.1191
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0057 0.0326 0.0325
Schistosoma mansoni protein kinase 0.0033 0.0062 0.016
Echinococcus granulosus serine:threonine protein kinase 3 0.0243 0.2373 0.5257
Brugia malayi Fibronectin type III domain containing protein 0.0051 0.026 0.0259
Loa Loa (eye worm) hypothetical protein 0.0117 0.0985 0.0984
Plasmodium vivax protein kinase Crk2 0.0104 0.0836 0.6259
Onchocerca volvulus 0.0065 0.0408 0.1165
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0114 0.0946 0.3591
Brugia malayi serine/threonine protein kinase 6 0.0131 0.1133 0.1132
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.013 0.1126 0.2494
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0046 0.0202 0.0447
Echinococcus granulosus cyclin dependent kinase 0.0104 0.0836 0.1851
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0055 0.0302 0.0774
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0055 0.0302 0.0972
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0117 0.0981 0.2513
Echinococcus granulosus tyrosine protein kinase HCK 0.0046 0.0204 0.045
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Leishmania major protein kinase, putative 0.0069 0.0456 0.1599
Brugia malayi protein kinase C II. 0.0164 0.1505 0.1504
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0561 0.1437
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0836 0.2963
Loa Loa (eye worm) hypothetical protein 0.0049 0.0236 0.0235
Entamoeba histolytica protein kinase, putative 0.0053 0.0275 0.1075
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0028 0.0001 0.0002
Echinococcus multilocularis roundabout 2 0.0073 0.0498 0.1277
Schistosoma mansoni protein kinase 0.0191 0.1794 0.4596
Plasmodium vivax unspecified product 0.0085 0.0628 0.4409
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0066 0.042 0.1239
Brugia malayi casein kinase I 0.0055 0.0302 0.0301
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0055 0.0302 0.0301
Loa Loa (eye worm) SRC-1 0.0069 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0039 0.0122 0.0121
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0057 0.0326 0.0835
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.1205 0.3088
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0039 0.0122 0.0121
Schistosoma mansoni tyrosine kinase 0.0196 0.1855 0.4755
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0144 0.1285 0.4969
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0122 0.0312
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.004 0.0136 0.0349
Echinococcus granulosus serine:threonine protein kinase 0.0099 0.0784 0.1736
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0104 0.0836 0.0835
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.2046 0.5244
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1464 0.3753
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0286 0.068
Trichomonas vaginalis AGC family protein kinase 0.0121 0.1029 0.3763
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0161 0.1464 0.3753
Brugia malayi Hr1 repeat family protein 0.0128 0.111 0.1109
Schistosoma mansoni hypothetical protein 0.0062 0.0375 0.0962
Loa Loa (eye worm) AUR protein kinase 0.0131 0.1133 0.1132
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0836 0.2963
Schistosoma mansoni protein kinase C 0.0036 0.009 0.0231
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0069 0.0456 0.1592
Onchocerca volvulus 0.003 0.0026 0.0065
Entamoeba histolytica protein kinase, putative 0.0258 0.2533 1
Entamoeba histolytica protein kinase, putative 0.004 0.0132 0.0509
Loa Loa (eye worm) hypothetical protein 0.0051 0.026 0.0259
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0131 0.1133 0.4466
Brugia malayi P21-Rho-binding domain containing protein 0.0032 0.0044 0.0043
Brugia malayi cell division control protein 2 homolog 0.0104 0.0836 0.0835
Brugia malayi protein unc-22 0.003 0.0027 0.0026
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0257 0.2522 0.6464
Loa Loa (eye worm) hypothetical protein 0.0121 0.1031 0.103
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.004 0.0132 0.0292
Plasmodium falciparum glycogen synthase kinase 3 0.0114 0.0946 0.7395
Giardia lamblia Kinase, STE STE20 0.0069 0.0456 0.1356
Echinococcus multilocularis Immunoglobulin 0.0049 0.0233 0.0597
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0075
Echinococcus granulosus Protein kinase C brain isozyme 0.0204 0.1946 0.4313
Giardia lamblia Aurora kinase 0.0131 0.1133 0.4189
Trypanosoma brucei protein kinase, putative 0.0114 0.0946 0.3576
Entamoeba histolytica serine/threonine protein kinase, putative 0.0257 0.2522 0.9959
Loa Loa (eye worm) hypothetical protein 0.014 0.124 0.1239
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0055 0.0302 0.0301
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0213 0.2046 0.2046
Loa Loa (eye worm) RasGEF domain-containing protein 0.0035 0.0076 0.0075
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0144 0.1285 0.4969
Schistosoma mansoni tyrosine kinase 0.014 0.1238 0.3172
Schistosoma mansoni tyrosine kinase 0.0157 0.142 0.3639
Echinococcus multilocularis serine:threonine protein kinase 0.0099 0.0784 0.2009
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0137 0.1205 0.1204
Loa Loa (eye worm) TK/ABL protein kinase 0.0028 0.0004 0.0003
Brugia malayi serine/threonine-protein kinase plk-2 0.0257 0.2522 0.2522
Echinococcus multilocularis tyrosine protein kinase Blk 0.0058 0.033 0.0846
Echinococcus multilocularis protein kinase shaggy 0.0114 0.0946 0.2424
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0251 0.2455 0.2455
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0066 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0075
Toxoplasma gondii AGC kinase 0.0057 0.0326 0.0271
Schistosoma mansoni hypothetical protein 0.0035 0.0076 0.0195
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.026 0.0259
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0437 0.4512 1
Echinococcus granulosus tyrosine protein kinase Srms 0.0028 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.009 0.0689 0.0688
Schistosoma mansoni unc-13 (munc13) 0.0036 0.009 0.0231
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0628 0.21
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0027 0.0026
Schistosoma mansoni protein kinase 0.007 0.0471 0.1207
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0121 0.1029 0.7974
Entamoeba histolytica hypothetical protein 0.0035 0.0076 0.0286
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0253 0.2487 0.2486
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.042 0.1077
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Echinococcus granulosus casein kinase I alpha 0.0055 0.0302 0.0667
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Giardia lamblia Kinase, CMGC GSK 0.0114 0.0946 0.3406
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0057 0.0326 0.1727
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0258 0.0662
Brugia malayi Protein kinase c protein 2 0.0093 0.0717 0.0716
Brugia malayi p70 ribosomal S6 kinase beta 0.0253 0.2487 0.2486
Echinococcus multilocularis serine:threonine protein kinase N2 0.0128 0.111 0.2844
Brugia malayi MAP kinase sur-1 0.0068 0.0446 0.0445
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.004 0.0132 0.0281
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0046 0.0202 0.0202
Echinococcus granulosus roundabout 2 0.0073 0.0498 0.1103
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0146 0.1303 0.5043
Echinococcus granulosus tyrosine protein kinase shark 0.0028 0.0004 0.0006
Schistosoma mansoni tyrosine kinase 0.0157 0.142 0.3639
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Echinococcus granulosus c src tyrosine kinase 0.0039 0.0127 0.028
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0114 0.0946 0.3591
Schistosoma mansoni tyrosine kinase 0.0069 0.0453 0.1162
Echinococcus multilocularis mitogen activated protein kinase 14 0.0144 0.1285 0.3293
Entamoeba histolytica protein kinase, putative 0.0253 0.2487 0.9818
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0161 0.1464 0.3753
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0057 0.0326 0.1067
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0232
Toxoplasma gondii AGC kinase 0.0253 0.2487 0.2489
Trypanosoma cruzi casein kinase, putative 0.0055 0.0302 0.0972
Echinococcus granulosus tyrosine kinase 0.0058 0.033 0.073
Trichomonas vaginalis AGC family protein kinase 0.0258 0.2533 1
Echinococcus granulosus casein kinase I delta 0.0055 0.0302 0.0667
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.004 0.0132 0.0339
Onchocerca volvulus 0.0038 0.0116 0.0325
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0243 0.2373 0.2372
Echinococcus granulosus neuroglian 0.006 0.0353 0.078
Echinococcus granulosus casein kinase I alpha 0.0055 0.0302 0.0667
Echinococcus granulosus aurora kinase A 0.0131 0.1133 0.251
Loa Loa (eye worm) hypothetical protein 0.004 0.0132 0.0132
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0114 0.0946 0.0945
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0128 0.111 0.1109
Plasmodium falciparum serine/threonine protein kinase KIN 0.004 0.0132 0.0579
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0028 0.0004 0.0009
Echinococcus multilocularis mitogen activated protein kinase 11 0.0144 0.1285 0.3293
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0199 0.1882 0.4824
Schistosoma mansoni tyrosine kinase 0.0196 0.1855 0.4755
Echinococcus multilocularis mitogen activated protein kinase 11 0.0144 0.1285 0.3293
Toxoplasma gondii histone kinase SNF1, putative 0.004 0.0132 0.0071
Leishmania major protein kinase A catalytic subunit 0.0057 0.0326 0.1071
Loa Loa (eye worm) hypothetical protein 0.0269 0.2655 0.2654
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0028 0.0004 0.0006
Brugia malayi Protein kinase domain containing protein 0.0089 0.0676 0.0676
Plasmodium falciparum serine/threonine protein kinase, putative 0.0131 0.1133 0.8962
Brugia malayi intracellular kinase 0.0114 0.0946 0.0945
Entamoeba histolytica casein kinase 1, putative 0.0055 0.0302 0.1179
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0122 0.0312
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0142 0.1257 1
Echinococcus multilocularis epidermal growth factor receptor 0.0157 0.142 0.3639
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0161 0.1464 0.3244
Loa Loa (eye worm) TK/EPH protein kinase 0.0099 0.0785 0.0785
Trichomonas vaginalis AGC family protein kinase 0.0133 0.1156 0.4289
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.092 0.3313
Trypanosoma cruzi cdc2-related kinase 3 0.0104 0.0836 0.3145
Echinococcus multilocularis casein kinase I alpha 0.0055 0.0302 0.0773
Trichomonas vaginalis STE family protein kinase 0.0049 0.0229 0.0447
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0382 0.3902 1
Echinococcus granulosus myotubularin protein 13 0.0039 0.0122 0.0269
Echinococcus multilocularis tyrosine protein kinase Srms 0.0058 0.033 0.0846
Schistosoma mansoni hypothetical protein 0.0032 0.0044 0.0113
Echinococcus multilocularis serine:threonine kinase SAD 1 0.004 0.0132 0.0337
Brugia malayi Protein kinase domain containing protein 0.0128 0.111 0.1109
Onchocerca volvulus 0.0295 0.2948 0.8485
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0102 0.0817 0.0816
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0055 0.0302 0.0668
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0069 0.0453 0.1162
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0069 0.0453 0.1162
Brugia malayi Protein kinase domain containing protein 0.0196 0.1855 0.1855
Loa Loa (eye worm) hypothetical protein 0.0073 0.0494 0.0493
Toxoplasma gondii diacylglycerol kinase, putative 0.0035 0.0076 0.0014
Loa Loa (eye worm) AUR protein kinase 0.0131 0.1133 0.1132
Echinococcus granulosus tyrosine protein kinase Lyn 0.0086 0.0639 0.1414
Giardia lamblia Kinase, CMGC CDK 0.0104 0.0836 0.2946
Schistosoma mansoni tyrosine kinase 0.0039 0.0127 0.0325
Echinococcus multilocularis insulin receptor 0.0196 0.1855 0.4755
Brugia malayi casein kinase 1, delta 0.0055 0.0302 0.0301
Entamoeba histolytica PH domain containing protein kinase, putative 0.0146 0.1303 0.5138
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0057 0.0326 0.1071
Brugia malayi protein kinase C3,putative 0.0135 0.1184 0.1184
Onchocerca volvulus 0.0312 0.3133 0.902
Echinococcus multilocularis cyclin dependent kinase 0.0104 0.0836 0.2143
Entamoeba histolytica casein kinase, putative 0.0085 0.0628 0.2469
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.006 0.0352 0.0779
Schistosoma mansoni tyrosine kinase 0.014 0.1238 0.3172
Loa Loa (eye worm) raf kinase 0.0035 0.0076 0.0075
Schistosoma mansoni tyrosine kinase 0.0028 0.0004 0.0009
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0128 0.111 0.2459
Plasmodium vivax casein kinase 1, putative 0.0055 0.0302 0.1511
Echinococcus granulosus raf serine:threonine protein kinase 0.0051 0.0258 0.0571
Schistosoma mansoni kinase 0.0275 0.2728 0.6991
Loa Loa (eye worm) hypothetical protein 0.009 0.0689 0.0688
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0446 0.1343
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.1133 0.2904
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0132 0.0339
Echinococcus granulosus tyrosine protein kinase Src42A 0.0069 0.0453 0.1003
Echinococcus granulosus calcium activated potassium channel 0.0079 0.0561 0.1242
Echinococcus granulosus casein kinase i 0.0055 0.0302 0.0667
Echinococcus granulosus serine threonine protein kinase nrc 0.0142 0.1257 0.2785
Brugia malayi RhoGAP domain containing protein 0.0046 0.0202 0.0202
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0114 0.0946 0.2095
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0112 0.0924 0.333
Toxoplasma gondii cytochrome p450 superfamily protein 0.0918 0.9803 1
Schistosoma mansoni protein kinase C mu 0.0134 0.117 0.2998
Schistosoma mansoni tyrosine kinase 0.0048 0.0226 0.058
Echinococcus multilocularis protein kinase c iota type 0.0247 0.2414 0.6186
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0058 0.033 0.0846
Loa Loa (eye worm) CAMK protein kinase 0.003 0.0027 0.0026
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0144 0.1285 0.1284
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0874 0.2241
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0068 0.0446 0.0445
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0106 0.0863 0.3253
Entamoeba histolytica hypothetical protein 0.0032 0.0044 0.0161
Trypanosoma cruzi cdc2-related kinase 1 0.0104 0.0836 0.3145
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0137 0.1205 0.3088
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0069 0.0453 0.1162
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0125 0.1072 0.2374
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.007 0.0471 0.1207
Echinococcus granulosus cyclin dependent kinase 1 0.0104 0.0836 0.1851
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Giardia lamblia Kinase, NEK 0.0121 0.1029 0.3754
Entamoeba histolytica protein kinase, putative 0.0107 0.0874 0.3443
Schistosoma mansoni protein kinase 0.0028 0.0001 0.0002
Echinococcus granulosus mitogen activated protein kinase 3 0.0068 0.0446 0.0986
Plasmodium vivax glycogen synthase kinase 3, putative 0.0114 0.0946 0.7235
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0142 0.1257 1
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.004 0.0132 0.0072
Echinococcus granulosus Immunoglobulin 0.0049 0.0233 0.0515
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0302 0.0774
Brugia malayi SH2 domain containing protein 0.0028 0.0004 0.0003
Trypanosoma brucei cdc2-related kinase 1 0.0104 0.0836 0.3132
Schistosoma mansoni hypothetical protein 0.0032 0.0044 0.0113
Echinococcus multilocularis protein kinase c eta type 0.0035 0.0076 0.0195
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0561 0.1437
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0446 0.1343
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0178 0.1659 0.4253
Echinococcus multilocularis serine:threonine protein kinase N2 0.0128 0.111 0.2844
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.004 0.0132 0.0131
Brugia malayi SRC-1 0.0069 0.0453 0.0453
Toxoplasma gondii casein kinase I 0.0055 0.0302 0.0246
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0036 0.009 0.0198
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0186 0.1748 0.3873
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0114 0.0946 0.2424
Echinococcus multilocularis myosin iiia 0.0069 0.0456 0.1168
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1133 0.4195
Echinococcus multilocularis serine:threonine protein kinase 3 0.0243 0.2373 0.6081
Loa Loa (eye worm) hypothetical protein 0.0054 0.0286 0.0285
Echinococcus multilocularis tyrosine protein kinase Abl 0.0039 0.0127 0.0325
Trypanosoma cruzi aurora B kinase, putative 0.0131 0.1133 0.4352
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.1946 0.4988
Echinococcus multilocularis aurora kinase A 0.0131 0.1133 0.2904
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0302 0.0773
Entamoeba histolytica diacylglycerol kinase, putative 0.0035 0.0076 0.0286
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0069 0.0453 0.1162
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.004 0.0132 0.0132
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.2455 0.6293
Echinococcus multilocularis mitogen activated protein kinase 14 0.0144 0.1285 0.3293
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0382 0.3902 0.3902
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Brugia malayi serine/threonine-protein kinase 6 0.0131 0.1133 0.1132
Schistosoma mansoni tyrosine kinase 0.0038 0.0116 0.0296
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0142 0.1257 0.3222
Echinococcus multilocularis RNA directed DNA polymerase 0.004 0.0136 0.0349
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.004 0.0132 0.0339
Trichomonas vaginalis STE family protein kinase 0.007 0.0471 0.1448
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0057 0.0326 0.2206
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.004 0.0132 0.0282
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0099 0.0789 0.0788
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0043
Loa Loa (eye worm) TK/INSR protein kinase 0.0196 0.1855 0.1855
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0099 0.0784 0.0783
Echinococcus granulosus cyclin dependent kinase 5 0.0104 0.0836 0.1851
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0036 0.009 0.0231
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.007 0.0471 0.1042
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0049 0.0233 0.0597
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0069 0.0456 0.1788
Echinococcus granulosus defective proboscis extension response 0.0049 0.0233 0.0515
Schistosoma mansoni protein kinase 0.004 0.0132 0.0339
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0186 0.1748 0.1748
Brugia malayi Variant SH3 domain containing protein 0.0046 0.0202 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.111 0.2844
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0107 0.0874 0.33
Plasmodium falciparum casein kinase 1 0.0055 0.0302 0.2002
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.2522 0.9957
Entamoeba histolytica protein kinase, putative 0.007 0.0471 0.1848
Echinococcus granulosus RNA directed DNA polymerase 0.004 0.0136 0.0301
Brugia malayi STE20-like kinase MST 0.0243 0.2373 0.2372
Toxoplasma gondii CMGC kinase, CK2 family 0.0085 0.0628 0.058
Brugia malayi Protein kinase domain containing protein 0.0107 0.0874 0.0874
Giardia lamblia Kinase, AGC PKA 0.0057 0.0326 0.0813
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0028 0.0004 0.0009
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0104 0.0836 0.3145
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0027 0.0069
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0069 0.0453 0.1003
Entamoeba histolytica PH domain containing protein kinase, putative 0.0146 0.1303 0.5138
Echinococcus multilocularis N chimaerin 0.0046 0.0202 0.0519
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.003 0.0027 0.0026
Echinococcus granulosus casein kinase ii subunit alpha 0.0085 0.0628 0.139
Schistosoma mansoni unc-13 (munc13) 0.0036 0.009 0.0231
Entamoeba histolytica p21-activated kinase 0.0075 0.0517 0.203
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0069 0.0453 0.1162
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.004 0.0132 0.0072
Loa Loa (eye worm) hypothetical protein 0.006 0.0352 0.0351
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0068 0.0446 0.1557
Brugia malayi SH2 domain containing protein 0.0028 0.0004 0.0003
Trypanosoma cruzi casein kinase, putative 0.0055 0.0302 0.0972
Echinococcus granulosus Rac GTPase activating protein 1 0.0035 0.0076 0.0167
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.2522 0.9957
Loa Loa (eye worm) hypothetical protein 0.012 0.1019 0.1019
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0204 0.1946 0.4988
Giardia lamblia Kinase, CK1 Casein kinase 0.0055 0.0302 0.0711
Entamoeba histolytica protein kinase domain containing protein 0.0033 0.0062 0.0233
Echinococcus multilocularis activin receptor type 0.0033 0.0062 0.016
Schistosoma mansoni vesicular amine transporter 0.0049 0.0233 0.0597
Plasmodium falciparum casein kinase 2, alpha subunit 0.0085 0.0628 0.4733
Entamoeba histolytica protein kinase, putative 0.0114 0.0946 0.3726
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.004 0.0132 0.0292
Toxoplasma gondii AGC kinase 0.0057 0.0326 0.0271
Echinococcus multilocularis calcium activated potassium channel 0.0079 0.0561 0.1437
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0148 0.0379
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0148 0.0326
Schistosoma mansoni ste20-related kinase 0.0191 0.1797 0.4606
Brugia malayi Protein kinase domain containing protein 0.0028 0.0004 0.0003
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0125 0.1072 0.2747
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.004 0.0132 0.0132
Brugia malayi WH1 domain containing protein 0.0032 0.0044 0.0043
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0066 0.042 0.1077
Trypanosoma cruzi cdc2-related kinase 3 0.0104 0.0836 0.3145
Loa Loa (eye worm) hypothetical protein 0.004 0.0136 0.0136
Trypanosoma cruzi casein kinase, putative 0.0055 0.0302 0.0972
Loa Loa (eye worm) TK protein kinase 0.0058 0.033 0.0329
Schistosoma mansoni protein kinase 0.004 0.0132 0.0339
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1133 0.4195
Trypanosoma cruzi polo-like protein kinase, putative 0.0257 0.2522 1
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.004 0.0132 0.0281
Schistosoma mansoni protein kinase 0.0032 0.0044 0.0113
Trichomonas vaginalis AGC family protein kinase 0.0258 0.2533 1
Echinococcus multilocularis hypothetical protein 0.0062 0.0375 0.0962
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0132 0.0337
Echinococcus granulosus tyrosine protein kinase Src64B 0.0069 0.0453 0.1003
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0114 0.0946 0.2424
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0131 0.1133 0.4466
Echinococcus multilocularis nervana 2 0.0125 0.1072 0.2747
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0157 0.142 0.3145
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0178 0.1659 0.1659
Entamoeba histolytica protein kinase 2, putative 0.0142 0.1257 0.4957
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0079 0.0561 0.056
Echinococcus multilocularis myotubularin protein 13 0.0039 0.0122 0.0312
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0191 0.1794 0.4596
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Entamoeba histolytica diacylglycerol kinase, putative 0.0035 0.0076 0.0286
Brugia malayi Protein kinase domain containing protein 0.0172 0.1586 0.1585
Echinococcus multilocularis dual specificity 0.0107 0.0874 0.2241
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0057 0.0326 0.0721
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0178 0.1659 0.1659
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0257 0.2522 1
Echinococcus granulosus serine:threonine protein kinase N2 0.0128 0.111 0.2459
Echinococcus multilocularis unc 13 (munc13) 0.0036 0.009 0.0231
Echinococcus multilocularis casein kinase ii subunit alpha 0.0085 0.0628 0.1609
Echinococcus granulosus NDR protein kinase 0.0128 0.111 0.2459
Echinococcus granulosus serine:threonine protein kinase 0.0099 0.0784 0.1736
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0057 0.0326 0.0835
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0055 0.0302 0.0774
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0628 0.21
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0131 0.1133 0.251
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0446 0.1343
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0134 0.117 0.1169
Schistosoma mansoni protein kinase C mu 0.0035 0.0076 0.0195
Plasmodium falciparum calcium-dependent protein kinase 4 0.004 0.0132 0.0584
Trichomonas vaginalis CAMK family protein kinase 0.0079 0.0561 0.1822
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0191 0.1794 0.3974
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0046 0.0202 0.0519
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0085 0.0628 0.0627
Echinococcus granulosus serine:threonine kinase SAD 1 0.004 0.0132 0.029
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0055 0.0302 0.0668
Loa Loa (eye worm) hypothetical protein 0.0082 0.0604 0.0603
Loa Loa (eye worm) hypothetical protein 0.0062 0.0375 0.0375
Leishmania major protein kinase A catalytic subunit isoform 1 0.0057 0.0326 0.1071
Leishmania major protein kinase, putative 0.0131 0.1133 0.4352
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0068 0.0446 0.1557
Schistosoma mansoni cell adhesion molecule 0.0062 0.0379 0.0971
Loa Loa (eye worm) hypothetical protein 0.0099 0.0784 0.0783
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1133 0.4195
Entamoeba histolytica hypothetical protein 0.0107 0.0874 0.3443
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0057 0.0326 0.0835
Trypanosoma brucei casein kinase I, isoform 2 0.0055 0.0302 0.0968
Brugia malayi RhoGEF domain containing protein 0.0035 0.0076 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0258 0.2533 1
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0326 0.0835
Echinococcus multilocularis c src tyrosine kinase 0.0039 0.0127 0.0325
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0132 0.0337
Onchocerca volvulus Tyrosine kinase homolog 0.0343 0.3473 1
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0085 0.0628 0.4409
Echinococcus granulosus tyrosine protein kinase Fyn 0.0069 0.0453 0.1003
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.1659 0.4253
Echinococcus granulosus Glutaredoxin protein 5 0.0125 0.1072 0.2374
Echinococcus granulosus titin 0.003 0.0027 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Plasmodium falciparum calcium-dependent protein kinase 2 0.004 0.0132 0.0584
Echinococcus granulosus protein kinase C gamma type 0.017 0.1565 0.3468
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0232
Schistosoma mansoni hypothetical protein 0.0032 0.0044 0.0113
Brugia malayi Protein kinase domain containing protein 0.0066 0.042 0.042
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0038 0.0116 0.0219
Onchocerca volvulus 0.014 0.124 0.3564
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0035 0.0076 0.0075
Echinococcus multilocularis casein kinase I delta 0.0055 0.0302 0.0773
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0039 0.0122 0.0121
Echinococcus granulosus tyrosine kinase 0.0028 0.0004 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0628 0.21
Schistosoma mansoni tyrosine kinase 0.0028 0.0004 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0128 0.111 0.4099
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.004 0.0132 0.0072
Schistosoma mansoni protein kinase 0.0028 0.0001 0.0002
Entamoeba histolytica protein kinase, putative 0.0041 0.0146 0.0564
Echinococcus granulosus epidermal growth factor receptor 0.0227 0.2192 0.4858
Giardia lamblia Kinase, STE STE20 0.007 0.0471 0.1419
Schistosoma mansoni vav2 0.005 0.0248 0.0636
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.11 0.11
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0107 0.0874 0.33
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0066 0.042 0.093
Entamoeba histolytica protein kinase domain containing protein 0.0114 0.0946 0.3726
Echinococcus granulosus N chimaerin 0.0046 0.0202 0.0447
Echinococcus multilocularis mitogen activated protein kinase 0.0068 0.0446 0.1142
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0104 0.0836 0.0835
Loa Loa (eye worm) hypothetical protein 0.0051 0.026 0.0259
Trichomonas vaginalis STE family protein kinase 0.0121 0.1029 0.3763
Brugia malayi RhoGAP domain containing protein 0.0035 0.0076 0.0075
Entamoeba histolytica protein kinase, putative 0.0258 0.2533 1
Echinococcus granulosus Diacylglycerol kinase theta 0.0035 0.0076 0.0167
Entamoeba histolytica protein kinase, putative 0.0053 0.0275 0.1075
Brugia malayi Protein kinase domain containing protein 0.0178 0.1659 0.1659
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0069 0.0456 0.1599
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0069 0.0453 0.1162
Schistosoma mansoni ephrin receptor 0.0081 0.059 0.1512
Echinococcus granulosus activin receptor type 0.0033 0.0062 0.0137
Trypanosoma brucei polo-like protein kinase 0.0257 0.2522 0.9958
Loa Loa (eye worm) AGC/PKN protein kinase 0.0128 0.111 0.1109
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0039 0.0122 0.0121
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.2522 0.9957
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0104 0.0836 0.0835
Entamoeba histolytica protein kinase , putative 0.0131 0.1133 0.4466
Entamoeba histolytica casein kinase, putative 0.0055 0.0302 0.1179
Entamoeba histolytica cell division protein kinase 2, putative 0.0104 0.0836 0.3292
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0199 0.1882 0.417
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0251 0.2455 0.6293
Trichomonas vaginalis AGC family protein kinase 0.0258 0.2533 1
Leishmania major protein kinase A catalytic subunit isoform 2 0.0057 0.0326 0.1071
Schistosoma mansoni protein kinase 0.007 0.0471 0.1207
Brugia malayi P38 map kinase family protein 2 0.0144 0.1285 0.1284
Echinococcus granulosus fibroblast growth factor receptor 4 0.0117 0.0981 0.2172
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0161 0.1464 0.3244
Schistosoma mansoni titin 0.003 0.0027 0.0069
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0035 0.0076 0.0075
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0068 0.0446 0.1557
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0628 0.2469
Entamoeba histolytica serine/threonine protein kinase, putative 0.004 0.0132 0.0507
Schistosoma mansoni hypothetical protein 0.0062 0.0375 0.0962
Entamoeba histolytica protein kinase, putative 0.0028 0.0007 0.0013
Brugia malayi ephrin receptor 1 precursor 0.0047 0.0213 0.0212
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.004 0.0132 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0921 0.2361
Brugia malayi Stress-activated protein kinase jnk-1 0.0251 0.2455 0.2455
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0057 0.0326 0.1067
Echinococcus granulosus serine/threonine protein kinase 0.0146 0.1303 0.2887
Echinococcus multilocularis tyrosine protein kinase shark 0.0028 0.0004 0.0009
Trypanosoma cruzi casein kinase, putative 0.0055 0.0302 0.0972
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0134 0.117 0.1169
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0392 0.4011 0.401
Echinococcus granulosus tyrosine protein kinase Fyn 0.0069 0.0453 0.1003
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0049 0.0233 0.0597
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0068 0.0446 0.1557
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.111 0.2844
Giardia lamblia Kinase, AGC PKA 0.0142 0.1257 0.4708
Giardia lamblia Kinase, NEK 0.0121 0.1029 0.3754
Echinococcus multilocularis casein kinase I alpha 0.0055 0.0302 0.0773
Entamoeba histolytica protein kinase, putative 0.0049 0.0229 0.0894
Entamoeba histolytica protein kinase, putative 0.0107 0.0874 0.3443
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0836 0.2963
Echinococcus granulosus unc 13 munc13 0.0036 0.009 0.0198
Brugia malayi phosphoinositide-dependent protein kinase I 0.0066 0.042 0.042
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0132 0.0337
Loa Loa (eye worm) AUR protein kinase 0.0131 0.1133 0.1132
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0561 0.1437
Echinococcus granulosus mitogen activated protein kinase 11 0.0144 0.1285 0.2846
Trichomonas vaginalis STE family protein kinase 0.007 0.0471 0.1448
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0117 0.0981 0.2172
Brugia malayi Protein kinase domain 0.007 0.0471 0.047
Echinococcus multilocularis Immunoglobulin 0.0049 0.0233 0.0597
Loa Loa (eye worm) hypothetical protein 0.0065 0.0408 0.0407
Trichomonas vaginalis STE family protein kinase 0.0069 0.0456 0.1386
Echinococcus granulosus epidermal growth factor receptor 0.0157 0.142 0.3145
Plasmodium falciparum calcium-dependent protein kinase 3 0.004 0.0132 0.0584
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0382 0.3902 1
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.2522 0.9957
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.004 0.0132 0.0005
Plasmodium vivax calcium-dependent protein kinase, putative 0.004 0.0132 0.0005
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0069 0.0456 0.1788
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0628 0.21
Loa Loa (eye worm) hypothetical protein 0.0057 0.0326 0.0325
Schistosoma mansoni serine/threonine protein kinase 0.0312 0.3133 0.8029
Echinococcus multilocularis raf serine:threonine protein kinase 0.0051 0.0258 0.0662
Brugia malayi Protein kinase domain containing protein 0.0028 0.0004 0.0003
Entamoeba histolytica PH domain containing protein kinase, putative 0.0061 0.0372 0.1457
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0107 0.0874 0.0874
Schistosoma mansoni diacylglycerol kinase theta 0.0035 0.0076 0.0195
Schistosoma mansoni protein kinase 0.0085 0.0628 0.1609
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.004 0.0132 0.0005
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.004 0.0132 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.1505 0.3857
Echinococcus multilocularis Glutaredoxin protein 5 0.0125 0.1072 0.2747
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0057 0.0326 0.1067
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0107 0.0874 0.3286
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.013 0.1126 0.2885
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0936 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0069 0.0453 0.1162
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0117 0.0981 0.2513
Echinococcus granulosus nervana 2 0.0125 0.1072 0.2374
Brugia malayi hypothetical protein 0.0028 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.026 0.0259
Echinococcus granulosus protein kinase shaggy 0.0114 0.0946 0.2095
Loa Loa (eye worm) AGC/PKA protein kinase 0.0057 0.0326 0.0325
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.007 0.0471 0.1207
Schistosoma mansoni tyrosine kinase 0.014 0.1238 0.3172
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0075
Brugia malayi putative serine/threonine kinase SADA gamma 0.004 0.0132 0.0131
Brugia malayi Ras association domain family 1 isoform A 0.0035 0.0076 0.0075
Entamoeba histolytica protein kinase, putative 0.0055 0.0302 0.118
Entamoeba histolytica protein kinase, putative 0.0055 0.0302 0.118
Echinococcus multilocularis protein kinase c epsilon type 0.0164 0.1505 0.3857
Leishmania major casein kinase, putative 0.0055 0.0302 0.0972
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0131 0.1133 0.8898
Echinococcus granulosus tyrosine protein kinase ABL1 0.0028 0.0004 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0258 0.2533 1
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0131 0.1133 0.4466
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0946 0.3418
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0836 0.2143
Entamoeba histolytica protein kinase, putative 0.0128 0.111 0.4375
Brugia malayi Protein kinase domain containing protein 0.0028 0.0004 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Brugia malayi Protein kinase domain containing protein 0.0104 0.0836 0.0835
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0057 0.0326 0.0721
Schistosoma mansoni tyrosine kinase 0.0069 0.0453 0.1162
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0028 0.0007 0.0013
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0068 0.0446 0.1557
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0068 0.0446 0.1557
Schistosoma mansoni tyrosine kinase 0.0117 0.0981 0.2513
Echinococcus multilocularis rho associated protein kinase 0.0312 0.3133 0.8029
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0058 0.033 0.073
Echinococcus multilocularis PAK box P21 Rho binding 0.0032 0.0044 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0446 0.1142
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0039 0.0127 0.028
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0075
Loa Loa (eye worm) AGC/NDR protein kinase 0.0128 0.111 0.1109
Trypanosoma brucei Casein kinase II 0.0085 0.0628 0.2289
Echinococcus multilocularis serine:threonine protein kinase 0.0099 0.0784 0.2009
Giardia lamblia Kinase, CMGC MAPK 0.0068 0.0446 0.1313
Trichomonas vaginalis AGC family protein kinase 0.0057 0.0326 0.0847
Echinococcus granulosus ephrin type A receptor 4 A 0.0081 0.059 0.1306
Entamoeba histolytica cell division protein kinase 2, putative 0.0104 0.0836 0.3292
Brugia malayi serine/threonine kinase 12 0.0131 0.1133 0.1132
Plasmodium falciparum calcium-dependent protein kinase 5 0.004 0.0132 0.0584
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0114 0.0946 0.0945
Onchocerca volvulus 0.0114 0.0946 0.2716
Echinococcus granulosus casein kinase I alpha 0.0055 0.0302 0.0667
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0057 0.0326 0.1071
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Loa Loa (eye worm) AGC/AKT protein kinase 0.0258 0.2533 0.2532
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0069 0.0453 0.1003
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0041 0.0146 0.0145
Trypanosoma brucei SNF1-related protein kinases, putative 0.004 0.0132 0.028
Brugia malayi Protein kinase domain containing protein 0.0028 0.0004 0.0003
Schistosoma mansoni serine/threonine-protein kinase 0.0146 0.1303 0.3339
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.2522 0.9957
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.004 0.0132 0.028
Entamoeba histolytica hypothetical protein 0.0032 0.0044 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0446 0.1343
Schistosoma mansoni serine/threonine protein kinase 0.0257 0.2522 0.6464
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.004 0.0141 0.036
Onchocerca volvulus Serine\/threonine kinase homolog 0.0257 0.2522 0.7259
Schistosoma mansoni protein kinase 0.0055 0.0302 0.0773
Echinococcus multilocularis casein kinase i 0.0055 0.0302 0.0773
Trypanosoma brucei cdc2-related kinase 3 0.0104 0.0836 0.3132
Onchocerca volvulus 0.003 0.0027 0.0067
Giardia lamblia Kinase, CMGC CDK 0.0104 0.0836 0.2946
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0121 0.1029 0.0992
Entamoeba histolytica PH domain containing protein kinase, putative 0.0061 0.0372 0.1457
Trichomonas vaginalis STE family protein kinase 0.007 0.0471 0.1448
Trichomonas vaginalis AGC family protein kinase 0.0066 0.042 0.1239
Brugia malayi Protein kinase domain containing protein 0.0186 0.1748 0.1748
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0784 0.2746
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0046 0.0202 0.0519
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0057 0.0326 0.1071
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0213 0.2046 0.4534
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0032 0.0044 0.0113
Echinococcus multilocularis Diacylglycerol kinase theta 0.0035 0.0076 0.0195
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0069 0.0453 0.1162
Schistosoma mansoni serine/threonine-protein kinase 0.0146 0.1303 0.3339
Brugia malayi diacylglycerol kinase 0.0035 0.0076 0.0075
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.004 0.0141 0.031
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0066 0.042 0.042
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0257 0.2522 0.5589
Onchocerca volvulus 0.0117 0.0985 0.2828
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0032 0.0044 0.0096
Echinococcus multilocularis cyclin dependent kinase 5 0.0104 0.0836 0.2143
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0628 0.21
Brugia malayi Kinase associated domain 1 family protein 0.0062 0.0375 0.0375
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.007 0.0471 0.1042
Plasmodium falciparum calcium-dependent protein kinase 1 0.004 0.0132 0.0584
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0049 0.0233 0.0597
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0186 0.1748 0.448
Echinococcus multilocularis rac serine:threonine kinase 0.0146 0.1303 0.3339
Echinococcus granulosus protein kinase c iota type 0.0247 0.2414 0.5349
Brugia malayi hypothetical protein 0.0051 0.026 0.0259
Onchocerca volvulus 0.0316 0.3171 0.913
Echinococcus multilocularis tyrosine protein kinase HCK 0.0046 0.0204 0.0522
Schistosoma mansoni nephrin 0.0062 0.038 0.0973
Echinococcus multilocularis cyclin dependent kinase 1 0.0104 0.0836 0.2143
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0128 0.111 0.2844
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0069 0.0453 0.1162
Trichomonas vaginalis CK1 family protein kinase 0.0055 0.0302 0.0746
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0075
Brugia malayi Tyrosine-protein kinase abl-1 0.0039 0.0127 0.0126
Loa Loa (eye worm) hypothetical protein 0.0075 0.0517 0.0517
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0107 0.0874 0.33
Entamoeba histolytica protein kinase, putative 0.0131 0.1133 0.4466
Entamoeba histolytica protein kinase, putative 0.0046 0.0204 0.0791
Loa Loa (eye worm) hypothetical protein 0.0087 0.0651 0.065
Schistosoma mansoni diacylglycerol kinase theta 0.0035 0.0076 0.0195
Loa Loa (eye worm) TK protein kinase 0.0046 0.0204 0.0203
Brugia malayi Protein kinase domain containing protein 0.0128 0.111 0.1109
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0111 0.0921 0.2361
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0137 0.1205 0.1204
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0382 0.3902 0.8647
Trypanosoma brucei protein kinase, putative 0.0068 0.0446 0.1551
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0032 0.0044 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0836 0.2143
Brugia malayi Casein kinase II, alpha chain 0.0085 0.0628 0.0627
Trichomonas vaginalis CK1 family protein kinase 0.0055 0.0302 0.0746
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.007 0.0471 0.1042
Echinococcus multilocularis Rac GTPase activating protein 1 0.0035 0.0076 0.0195
Echinococcus multilocularis cyclin dependent kinase 1 0.0104 0.0836 0.2143
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0039 0.0122 0.0241
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0058 0.0336 0.0335
Loa Loa (eye worm) hypothetical protein 0.0071 0.0472 0.0471
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0132 0.0041
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0141 0.1252 0.1251
Brugia malayi diacylglycerol kinase 0.0035 0.0076 0.0075
Echinococcus multilocularis tyrosine kinase 0.0028 0.0004 0.0009
Loa Loa (eye worm) AGC/PKA protein kinase 0.0057 0.0326 0.0325
Schistosoma mansoni protein kinase 0.004 0.0132 0.0339
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0137 0.1205 0.2669
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0104 0.0836 0.3145
Echinococcus multilocularis serine threonine protein kinase 0.017 0.1565 0.4012
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0039 0.0127 0.0325
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0057 0.0326 0.0835
Echinococcus multilocularis 0.0064 0.0403 0.1033
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.007 0.0471 0.1207
Echinococcus granulosus mitogen activated protein kinase 14 0.0144 0.1285 0.2846
Trypanosoma cruzi casein kinase II, putative 0.0085 0.0628 0.2299
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.111 0.2844
Trypanosoma cruzi SNF1-related protein kinases, putative 0.004 0.0132 0.0281
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0046 0.0202 0.0519
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0144 0.1285 0.4969
Echinococcus granulosus tyrosine protein kinase Blk 0.0058 0.033 0.073
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0308 0.3086 0.3085
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0032 0.0044 0.0043
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0142 0.1257 0.4856
Trichomonas vaginalis AGC family protein kinase 0.0258 0.2533 1
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0628 0.21
Entamoeba histolytica protein kinase domain containing protein 0.0131 0.1133 0.4466
Brugia malayi serine/threonine-protein kinase PAK 7 0.0218 0.2097 0.2097
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0132 0.0337
Brugia malayi Pleckstrin Homology Domain 0.0039 0.0122 0.0121
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.2522 0.9957
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0178 0.1659 0.3677
Trypanosoma brucei rac serine-threonine kinase, putative 0.0258 0.2533 1
Echinococcus multilocularis PAK box P21 Rho binding 0.0049 0.0229 0.0588
Giardia lamblia Kinase, NEK 0.0121 0.1029 0.3754
Brugia malayi protein-tyrosine kinase 0.0058 0.033 0.0329
Schistosoma mansoni tyrosine kinase 0.0227 0.2192 0.5618
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0178 0.1659 0.4772
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0164 0.1505 0.1504
Echinococcus granulosus PAK box P21 Rho binding 0.0032 0.0044 0.0096
Entamoeba histolytica protein kinase domain containing protein 0.0114 0.0946 0.3726
Trichomonas vaginalis AGC family protein kinase 0.0128 0.111 0.4099
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0068 0.0446 0.1551
Entamoeba histolytica protein kinase domain containing protein 0.0107 0.0874 0.3443
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0628 0.21
Brugia malayi Protein kinase domain containing protein 0.0079 0.0561 0.056
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.004 0.0132 0.0292
Plasmodium falciparum protein kinase 5 0.0104 0.0836 0.6475
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0111 0.0921 0.2041
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0921 0.2361
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0218 0.2097 0.2097
Trypanosoma cruzi p21-activated kinase 3, putative 0.0039 0.0122 0.0241
Echinococcus granulosus c-Jun N-terminal kinases 0.0251 0.2455 0.5441
Schistosoma mansoni rac gtpase activating protein 0.0035 0.0076 0.0195
Onchocerca volvulus 0.0055 0.0302 0.0859
Trichomonas vaginalis STE family protein kinase 0.007 0.0471 0.1448
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0128 0.111 0.2459
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1464 0.3753
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0128 0.111 0.2844
Leishmania major protein kinase, putative 0.004 0.0132 0.0283
Loa Loa (eye worm) hypothetical protein 0.014 0.124 0.1239
Onchocerca volvulus 0.0121 0.1031 0.296
Echinococcus granulosus nervana 2 0.0125 0.1072 0.2374
Entamoeba histolytica protein kinase, putative 0.0066 0.042 0.1648
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.004 0.0132 0.0281
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0946 0.3418
Brugia malayi Cam kinase protein 1 0.004 0.0132 0.0132
Loa Loa (eye worm) TK/EGFR protein kinase 0.0227 0.2192 0.2192
Echinococcus multilocularis neuroglian 0.006 0.0353 0.0904
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0326 0.0835
Schistosoma mansoni serine/threonine kinase 0.0079 0.0561 0.1437
Trypanosoma cruzi cdc2-related kinase 1 0.0104 0.0836 0.3145
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.092 0.3313
Schistosoma mansoni protein kinase 0.0131 0.1133 0.2904
Echinococcus granulosus dual specificity 0.0107 0.0874 0.1936
Echinococcus multilocularis ephrin type A receptor 4 A 0.0081 0.059 0.1512
Brugia malayi P21-Rho-binding domain containing protein 0.0032 0.0044 0.0043
Echinococcus multilocularis casein kinase I alpha 0.0055 0.0302 0.0773
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0213 0.2046 0.5244
Echinococcus multilocularis titin 0.003 0.0027 0.0069
Trichomonas vaginalis CK1 family protein kinase 0.0055 0.0302 0.0746
Giardia lamblia Kinase, CMGC CK2 0.0085 0.0628 0.2076
Brugia malayi Immunoglobulin I-set domain containing protein 0.0392 0.4011 0.401
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0004 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.1946 0.4988
Schistosoma mansoni atypical protein kinase C 0.0253 0.2482 0.636
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0178 0.1659 0.1659
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.004 0.0132 0.0132
Echinococcus granulosus insulin receptor 0.0196 0.1855 0.4111
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0104 0.0836 0.0794
Brugia malayi Temporarily assigned gene name protein 59 0.013 0.1131 0.113
Echinococcus multilocularis nervana 2 0.0125 0.1072 0.2747
Echinococcus granulosus rho-associated protein kinase 1 0.0312 0.3133 0.6943
Giardia lamblia Kinase, AGC AKT 0.0102 0.0817 0.2866
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0028 0.0001 0.0002
Echinococcus granulosus mitogen activated protein kinase 0.0068 0.0446 0.0986
Trypanosoma brucei aurora B kinase 0.0131 0.1133 0.4334
Echinococcus granulosus tyrosine protein kinase Fyn 0.0069 0.0453 0.1003
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.004 0.0132 0.0005
Plasmodium falciparum NIMA related kinase 1 0.0121 0.1029 0.8091
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.1748 0.4481
Echinococcus granulosus protein kinase c eta type 0.0035 0.0076 0.0167
Onchocerca volvulus 0.0082 0.0604 0.1729
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0032 0.0044 0.0113
Trypanosoma cruzi polo-like protein kinase, putative 0.0257 0.2522 1
Leishmania major casein kinase II, putative 0.0085 0.0628 0.2299
Brugia malayi Protein kinase domain containing protein 0.0099 0.0784 0.0783
Echinococcus multilocularis casein kinase I delta 0.0055 0.0302 0.0773
Echinococcus granulosus casein kinase I delta 0.0055 0.0302 0.0667
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.2522 0.9957
Schistosoma mansoni serine/threonine kinase 0.0128 0.111 0.2844
Brugia malayi C1-like domain containing protein 0.0134 0.117 0.1169
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0089
Trypanosoma cruzi Protein kinase B 0.0146 0.1303 0.5043
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0057 0.0326 0.0271
Echinococcus granulosus protein kinase c epsilon type 0.0164 0.1505 0.3334
Trichomonas vaginalis AGC family protein kinase 0.0128 0.111 0.4099

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 816 nM Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detector ChEMBL. 24900349
IC50 (binding) = 816 nM Cellular Inhibition Assay BINDINGDB. No reference
IC50 (binding) > 1000 nM Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detector ChEMBL. 24900349
IC50 (binding) > 1000 nM Cellular Inhibition Assay BINDINGDB. No reference
IC50 (binding) > 200000 nM Inhibition Assay BINDINGDB. No reference
IC50 (binding) > 100 um PUBCHEM_BIOASSAY: GAPDH Dose Response Colorimetric Assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (binding) > 100 uM PUBCHEM_BIOASSAY: SAR analysis of an In Vitro TNAP Dose Response Luminescent Assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1548, AID1574, AID1577, AID1659, AID518] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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