Detailed information for compound 1401735

Basic information

Technical information
  • TDR Targets ID: 1401735
  • Name: 2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxoimid azolidin-1-yl]-N-[4-(6-methyl-1,3-benzothiazo l-2-yl)phenyl]acetamide
  • MW: 500.569 | Formula: C27H24N4O4S
  • H donors: 2 H acceptors: 4 LogP: 4.38 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc(cc1)C1(C)NC(=O)N(C1=O)CC(=O)Nc1ccc(cc1)c1sc2c(n1)ccc(c2)C
  • InChi: 1S/C27H24N4O4S/c1-16-4-13-21-22(14-16)36-24(29-21)17-5-9-19(10-6-17)28-23(32)15-31-25(33)27(2,30-26(31)34)18-7-11-20(35-3)12-8-18/h4-14H,15H2,1-3H3,(H,28,32)(H,30,34)
  • InChiKey: IPOUKHNMIBKMTR-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]acetamide
  • 2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxo-1-imidazolidinyl]-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]acetamide
  • 2-[2,5-diketo-4-(4-methoxyphenyl)-4-methyl-imidazolidin-1-yl]-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]acetamide
  • 2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]ethanamide
  • MLS000334828
  • SMR000249586
  • T5310773

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70 family Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Candida albicans similar to S. cerevisiae KAR2 (YJL034W) HSP70/ BiP family ATPase and chaperone involved in translocation of nascent polypeptides Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense glucose-regulated protein 78, putative,luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70 (HSP70)-4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Giardia lamblia Bip Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K09490 heat shock 70kDa protein 5, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock 70 kDa protein 1 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium parvum heat shock 70 (HSP70) protein Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans Cytoplasmic chaperone Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock kda protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock kda protein Get druggable targets OG5_126588 All targets in OG5_126588
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica 70 kDa heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum similar to Heat shock 70 kDa protein cognate 4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock 70 kDa protein 1A:1B Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania braziliensis heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock protein 70 (HSP70) Get druggable targets OG5_126588 All targets in OG5_126588
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium yoelii heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania mexicana heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70kD, putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium falciparum heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein kDa heat shock kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Cryptosporidium parvum heat shock protein, Hsp70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium hominis heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Onchocerca volvulus Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi heat shock protein 70 (hsp70), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock 70 kda protein 1a Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi heat shock 70 kDa protein C precursor Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum similar to Heat shock 70 kDa protein homolog, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Leishmania infantum heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei heat shock protein 70 (hsp70), putative Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70kD, putative Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium falciparum heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium hominis heat shock protein 70 precursor Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense glucose-regulated protein 78, putative,luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium vivax heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus 3'partial|5'partial|heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum hypothetical protein Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium berghei heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii chaperonin protein BiP Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Babesia bovis dnaK protein Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Theileria parva heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania major heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat Shock protein family member hsp 3 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium yoelii heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein kDa Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis microsomal stress 70 protein ATPase core precursor, putative Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70b Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70b Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium berghei heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi heat shock protein 70 (hsp70), putative Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis Heat Shock protein family member (hsp 3) Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70 family Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70 (HSP70)-4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Toxoplasma gondii heat shock protein HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70 (HSP70)-4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Babesia bovis heat shock protein 70 precursor, putative Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Candida albicans heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) heat shock 70kDa protein 5 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum Heat shock protein 70 (Precursor), related Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans Cytoplasmic chaperone Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Cytosolic HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein kDa heat shock kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum Heat shock protein 70, related Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Plasmodium falciparum heat shock protein 70 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 654 aa 613 aa 51.9 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0007 0.001 0.0011
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0007 0.001 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0016 0.0935
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0016 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.001 0.0011
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0261 1
Schistosoma mansoni biogenic amine receptor 0.0007 0.001 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0295 0.0329
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0017 0.0019
Echinococcus granulosus neuropeptide Y receptor 0.0007 0.001 0.0011
Brugia malayi G protein-coupled receptor F59B2.13 0.0007 0.001 0.001
Brugia malayi hypothetical protein 0.0007 0.0011 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0016 0.0935
Loa Loa (eye worm) hypothetical protein 0.0021 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.001 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0005 0.0001 0.0001
Loa Loa (eye worm) melatonin receptor type 1A 0.0007 0.001 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0067 0.4411
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0008 0.0016 0.0611
Onchocerca volvulus 0.0007 0.0011 0.0012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0014 0.0687
Loa Loa (eye worm) hypothetical protein 0.0021 0.0072 0.0072
Onchocerca volvulus 0.0008 0.0016 0.0018
Echinococcus multilocularis protein patched 0.0051 0.0198 0.0222
Echinococcus granulosus neuropeptides capa receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.001 0.0011
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0007 0.001 0.001
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0687
Echinococcus multilocularis G protein coupled receptor 139 0.0007 0.001 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0007 0.001 0.0011
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0171 0.0171
Echinococcus granulosus orexin receptor type 2 0.0007 0.001 0.0011
Echinococcus granulosus g protein coupled receptor 0.0007 0.001 0.0011
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0489 0.0546
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0175 0.0195
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Toxoplasma gondii hypothetical protein 0.0007 0.0011 0.0415
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0103 0.2097
Echinococcus multilocularis neuropeptides capa receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.001 0.0011
Schistosoma mansoni neuropeptide F-like receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.001 0.0011
Brugia malayi neuropeptide F receptor 0.0007 0.001 0.001
Echinococcus granulosus cpg binding protein 0.0037 0.0137 0.0153
Schistosoma mansoni neuropeptide f receptor 76f 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0008 0.0016 0.0018
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0008 0.0016 0.1059
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Brugia malayi Patched related family protein 10 0.0007 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0016 0.0805
Schistosoma mansoni growth hormone secretagogue receptor 0.0007 0.001 0.0011
Echinococcus granulosus vesicular acetylcholine transporter 0.2096 0.8949 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0103 0.6
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0008 0.0016 0.1059
Schistosoma mansoni neuropeptide receptor 0.0007 0.001 0.0011
Echinococcus multilocularis neuropeptide receptor 0.0007 0.001 0.0011
Echinococcus granulosus muscleblind protein 0.018 0.0752 0.084
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0049 0.019 0.0213
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0067 0.4411
Loa Loa (eye worm) hypothetical protein 0.0286 0.1202 0.1202
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0016 0.0016
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0016 0.0016
Brugia malayi CHE-14 protein 0.0051 0.0198 0.0198
Schistosoma mansoni biogenic amine (5HT) receptor 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Echinococcus granulosus 7tm_1 domain containing protein 0.0007 0.001 0.0011
Echinococcus multilocularis somatostatin receptor 0.0007 0.001 0.0011
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0687
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0171 0.3496
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0072 0.0072
Leishmania major acetyl-CoA synthetase, putative 0.0008 0.0016 0.0016
Echinococcus multilocularis geminin 0.0205 0.0856 0.0956
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0008 0.0016 0.0327
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.001 0.0011
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Brugia malayi CXXC zinc finger family protein 0.0035 0.0128 0.0128
Brugia malayi sulfakinin receptor protein 0.0007 0.001 0.001
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0171 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0014 0.0687
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0103 0.0103
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0008 0.0016 0.0935
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0007 0.001 0.0011
Brugia malayi G protein-coupled receptor 0.0007 0.001 0.001
Echinococcus granulosus neuropeptide Y receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.0011 0.0012
Loa Loa (eye worm) G-protein coupled receptor 0.0007 0.001 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.001 0.0011
Echinococcus multilocularis serotonin receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.001 0.0011
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.001 0.0011
Brugia malayi Inositol-1 0.0045 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0007 0.001 0.0011
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0007 0.001 0.0011
Onchocerca volvulus Neuropeptide F receptor homolog 0.0007 0.001 0.0011
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0171 0.0171
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.0011 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.001 0.0011
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0016 0.0805
Loa Loa (eye worm) hypothetical protein 0.0062 0.0247 0.0247
Brugia malayi hypothetical protein 0.0182 0.0761 0.0761
Loa Loa (eye worm) neuropeptide F receptor 0.0007 0.001 0.001
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0008 0.0016 0.0935
Loa Loa (eye worm) hypothetical protein 0.018 0.0752 0.0752
Brugia malayi larval opioid receptor 0.0007 0.001 0.001
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0008 0.0016 0.1059
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.2096 0.8949 0.8949
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni inositol monophosphatase 0.0045 0.0171 0.0191
Schistosoma mansoni survival motor neuron protein 0.0058 0.0229 0.0256
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0016 0.1059
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Onchocerca volvulus Protein patched homolog 0.0007 0.0011 0.0012
Echinococcus granulosus dro:myosuppressin receptor 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0182 0.0761 0.0761
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0007 0.001 0.0011
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0017 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0007 0.001 0.0011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0175 0.0175
Echinococcus multilocularis muscleblind protein 1 0.018 0.0752 0.084
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Mycobacterium ulcerans hypothetical protein 0.0029 0.0103 0.6
Loa Loa (eye worm) hypothetical protein 0.1197 0.5101 0.5101
Echinococcus multilocularis g protein coupled receptor 0.0007 0.001 0.0011
Echinococcus multilocularis orexin receptor type 2 0.0007 0.001 0.0011
Loa Loa (eye worm) patched family protein 0.0007 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0058 0.0229 0.0256
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.001 0.0011
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Echinococcus multilocularis g-protein coupled receptor 0.0007 0.001 0.0011
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0007 0.001 0.0011
Echinococcus granulosus G protein coupled receptor 139 0.0007 0.001 0.0011
Brugia malayi GnHR receptor homolog 0.0007 0.001 0.001
Onchocerca volvulus 0.0035 0.0128 0.0144
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Echinococcus multilocularis expressed conserved protein 0.0112 0.0458 0.0512
Echinococcus multilocularis g protein coupled receptor 0.0007 0.001 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.001 0.0011
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0051 0.0198 0.0198
Loa Loa (eye worm) G-protein coupled receptor 0.0007 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0049 0.019 0.0213
Echinococcus multilocularis neuropeptide s receptor 0.0007 0.001 0.0011
Echinococcus granulosus peptide allatostatin:somatostatin 0.0007 0.001 0.0011
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0016 0.1059
Echinococcus granulosus neuropeptide FF receptor 2 0.0007 0.001 0.0011
Echinococcus multilocularis fmrfamide receptor 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0016 0.0016
Brugia malayi Dopamine receptor 0.0007 0.001 0.001
Brugia malayi Patched related family protein 12 0.0007 0.0011 0.0011
Brugia malayi Tachykinin-like peptides receptor 99D 0.0007 0.001 0.001
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0007 0.001 0.001
Onchocerca volvulus 0.0007 0.001 0.0011
Toxoplasma gondii patched family protein 0.0007 0.0011 0.0415
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Echinococcus multilocularis neuropeptide receptor A26 0.0007 0.001 0.0011
Echinococcus granulosus neuropeptide s receptor 0.0007 0.001 0.0011
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0016 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0103 0.0103
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0171 0.5
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0016 0.0935
Onchocerca volvulus Protein patched homolog 0.0007 0.0011 0.0012
Brugia malayi hypothetical protein 0.0286 0.1202 0.1202
Brugia malayi G-protein coupled receptor 0.0007 0.001 0.001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.001 0.0011
Brugia malayi hypothetical protein 0.0007 0.0011 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0103 0.6795
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0007 0.001 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0014 0.0687
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0007 0.001 0.0011
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0171 0.8615
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0008 0.0016 0.1059
Echinococcus granulosus g-protein coupled receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0008 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0016 0.1059
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.001 0.0011
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0497 0.0555
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0007 0.001 0.001
Onchocerca volvulus 0.0007 0.001 0.0011
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0103 0.6
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0016 0.0935
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Schistosoma mansoni opsin-like receptor 0.0007 0.001 0.0011
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0007 0.001 0.0011
Echinococcus multilocularis neuropeptides capa receptor 0.0007 0.001 0.0011
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0103 0.6795
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.001 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0687
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0025 0.0025
Echinococcus granulosus g protein coupled receptor 0.0007 0.001 0.0011
Schistosoma mansoni hypothetical protein 0.0007 0.001 0.0011
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0007 0.001 0.0011
Echinococcus multilocularis sex peptide receptor 0.0007 0.001 0.0011
Schistosoma mansoni amine GPCR 0.0007 0.001 0.0011
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0103 0.2097
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0007 0.001 0.0011
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Brugia malayi RE15519p 0.0007 0.001 0.001
Echinococcus multilocularis dro:myosuppressin receptor 0.0007 0.001 0.0011
Schistosoma mansoni neuropeptide receptor 0.0007 0.001 0.0011
Echinococcus granulosus alpha 1A adrenergic receptor 0.0007 0.001 0.0011
Schistosoma mansoni amine GPCR 0.0007 0.001 0.0011
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0008 0.0016 0.0935
Schistosoma mansoni biogenic amine receptor 0.0007 0.001 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0014 0.0687
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0171 0.0191
Brugia malayi Patched related family protein 4 0.0007 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0198 0.0222
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0008 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni neuropeptide F-like receptor 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Plasmodium vivax acetyl-CoA synthetase, putative 0.0008 0.0016 0.0844
Onchocerca volvulus 0.0007 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Brugia malayi AKH receptor 0.0007 0.001 0.001
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0171 0.0191
Onchocerca volvulus 0.0008 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0103 0.6795
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0008 0.0016 0.0935
Loa Loa (eye worm) hypothetical protein 0.0008 0.0016 0.0016
Echinococcus granulosus tachykinin peptides receptor 99D 0.0007 0.001 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0016 0.0016
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.1202 0.1343
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0029 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.001 0.0011
Schistosoma mansoni neuropeptide receptor 0.0007 0.001 0.0011
Echinococcus granulosus neuropeptide receptor 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0007 0.001 0.001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0007 0.001 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0014 0.0687
Schistosoma mansoni hypothetical protein 0.0205 0.0856 0.0956
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0103 0.0103
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0007 0.001 0.0011
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0171 0.8615
Brugia malayi hypothetical protein 0.0007 0.0011 0.0011
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.001 0.0011
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0008 0.0016 0.0844
Echinococcus multilocularis vesicular acetylcholine transporter 0.2096 0.8949 1
Brugia malayi follicle stimulating hormone receptor 0.0007 0.001 0.001
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0151 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0007 0.001 0.0011
Onchocerca volvulus 0.0058 0.0229 0.0256
Toxoplasma gondii patched family protein 0.0007 0.0011 0.0415
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Brugia malayi protein C24B5.3 0.0007 0.0011 0.0011
Loa Loa (eye worm) patched family protein 0.0007 0.0011 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.001 0.0011
Echinococcus granulosus 7TM GPCR rhodopsin 0.0007 0.001 0.0011
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0072 0.4742
Toxoplasma gondii patched family protein 0.0007 0.0011 0.0415
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.001 0.0011
Echinococcus multilocularis cpg binding protein 0.0037 0.0137 0.0153
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0008 0.0016 0.0611
Schistosoma mansoni hypothetical protein 0.0205 0.0856 0.0956
Echinococcus granulosus geminin 0.0205 0.0856 0.0956
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0026 0.0029
Echinococcus granulosus neuropeptide receptor A26 0.0007 0.001 0.0011
Echinococcus granulosus hypothetical protein 0.0007 0.001 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0016 0.0935
Toxoplasma gondii patched family protein 0.0007 0.0011 0.0415
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0008 0.0016 0.0935
Onchocerca volvulus 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0049 0.019 0.0213
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0687
Loa Loa (eye worm) patched family protein 0.0007 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0049 0.019 0.0213
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0014 0.0687
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0171 0.0171
Onchocerca volvulus 0.0007 0.001 0.0011
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0103 0.6795
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0198 0.0222
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Echinococcus multilocularis serotonin receptor 0.0007 0.001 0.0011
Schistosoma mansoni biogenic amine (5HT) receptor 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0016 0.0016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.001 0.0011
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Schistosoma mansoni amine GPCR 0.0007 0.001 0.0011
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.0707 0.079
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0072 1
Schistosoma mansoni patched 1 0.0051 0.0198 0.0222
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Onchocerca volvulus 0.0007 0.001 0.0011
Schistosoma mansoni hypothetical protein 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.018 0.0752 0.0752
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.1202 0.1343
Schistosoma mansoni hypothetical protein 0.0007 0.001 0.0011
Echinococcus granulosus expressed conserved protein 0.0112 0.0458 0.0512
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0072 1
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0687
Loa Loa (eye worm) patched family protein 0.0007 0.0011 0.0011
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0151 1
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.001 0.0011
Schistosoma mansoni opsin-like receptor 0.0007 0.001 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0014 0.0687
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0008 0.0016 0.0016
Brugia malayi Melatonin receptor type 1A 0.0007 0.001 0.001
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Schistosoma mansoni inositol monophosphatase 0.0045 0.0171 0.0191
Schistosoma mansoni cpg binding protein 0.0037 0.0137 0.0153
Loa Loa (eye worm) hypothetical protein 0.0029 0.0103 0.0103
Loa Loa (eye worm) oxidoreductase 0.0008 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Onchocerca volvulus 0.0007 0.001 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0175 0.0195
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Loa Loa (eye worm) neuropeptide F receptor 0.0007 0.001 0.001
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0103 0.0103
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Echinococcus granulosus sex peptide receptor 0.0007 0.001 0.0011
Echinococcus granulosus somatostatin receptor 0.0007 0.001 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0175 0.0195
Echinococcus granulosus neuropeptide receptor 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0175 0.0195
Mycobacterium ulcerans acetyl-CoA synthetase 0.0008 0.0016 0.0935
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0103 0.2097
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0026 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.001 0.0011
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0008 0.0016 0.1059
Loa Loa (eye worm) hypothetical protein 0.0029 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Onchocerca volvulus 0.0007 0.0011 0.0012
Echinococcus multilocularis protein dispatched 1 0.0058 0.0229 0.0256
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0103 0.6
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.001 0.0011
Loa Loa (eye worm) inositol-1 0.0045 0.0171 0.0171
Schistosoma mansoni opsin-like receptor 0.0007 0.001 0.0011
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0007 0.001 0.0011
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0103 0.6
Brugia malayi Dopamine receptor protein 2 0.0007 0.001 0.001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0175 0.0175
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0007 0.001 0.0011
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0008 0.0016 0.0935
Echinococcus multilocularis muscleblind protein 0.018 0.0752 0.084
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0128 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0687
Schistosoma mansoni vesicular acetylcholine transporter 0.2096 0.8949 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0007 0.001 0.001
Schistosoma mansoni neuropeptide receptor 0.0007 0.001 0.0011
Brugia malayi Patched protein homolog 1 0.0007 0.0011 0.0011
Onchocerca volvulus 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.001 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.001 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0067 0.4411
Schistosoma mansoni acetyl-CoA synthetase 0.0008 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0072 0.4187
Schistosoma mansoni amine GPCR 0.0007 0.001 0.0011
Echinococcus granulosus allatostatin A receptor 0.0007 0.001 0.0011
Brugia malayi putative neuropeptide receptor NPR1 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0175 0.0195
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni cpg binding protein 0.0035 0.0128 0.0144
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0103 0.6
Brugia malayi G-protein coupled receptor 0.0007 0.001 0.001
Brugia malayi ORL1-like opioid receptor 0.0007 0.001 0.001
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0007 0.001 0.0011
Schistosoma mansoni alpha-1 adrenergic receptor 0.0007 0.001 0.0011
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0014 0.0687
Onchocerca volvulus 0.0007 0.001 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.001 0.0011
Brugia malayi putative neuropeptide receptor 0.0007 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0687
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.001 0.0011
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0008 0.0016 0.1059
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0103 0.6
Brugia malayi protein C24B5.3 0.0007 0.0011 0.0011
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Onchocerca volvulus 0.0182 0.0761 0.085
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Onchocerca volvulus 0.0007 0.0011 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.001 0.0011
Schistosoma mansoni myosin xvIII 0.0007 0.001 0.0011
Schistosoma mansoni hypothetical protein 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0687
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Echinococcus granulosus dnaJ subfamily B 0.0494 0.2094 0.234
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0198 0.0198
Echinococcus granulosus fmrfamide receptor 0.0007 0.001 0.0011
Echinococcus multilocularis neuropeptide Y receptor 0.0007 0.001 0.0011
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0489 0.0489
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Leishmania major acetyl-CoA synthetase, putative 0.0008 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0007 0.001 0.0011
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.2096 0.8949 1
Schistosoma mansoni biogenic amine receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0008 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0494 0.2094 0.234
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Echinococcus multilocularis neuropeptide receptor 0.0007 0.001 0.0011
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0007 0.001 0.0011
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.0707 0.079
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0016 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.001 0.0011
Loa Loa (eye worm) TYRA-2 protein 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0008 0.0016 0.1059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0687
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Schistosoma mansoni adenoreceptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.001 0.0011
Echinococcus multilocularis fmrfamide receptor 0.0007 0.001 0.0011
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0007 0.001 0.0011
Brugia malayi vesicular acetylcholine transporter unc-17 0.2096 0.8949 0.8949
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0171 0.8615
Schistosoma mansoni histamine h1 receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0007 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Brugia malayi neuropeptide F receptor 0.0007 0.001 0.001
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0008 0.0016 0.0935
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0026 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.001 0.0011
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0171 0.6542
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0007 0.001 0.0011
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0008 0.0016 0.1059
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0016 0.0935
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.001 0.0011
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0008 0.0016 0.1059
Brugia malayi Dopamine receptor protein 1 0.0007 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.001 0.0011
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0007 0.001 0.001
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0008 0.0016 0.0016
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Onchocerca volvulus 0.0007 0.001 0.0011
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0008 0.0016 0.0935
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0017 0.0019
Brugia malayi hypothetical protein 0.0007 0.0011 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0103 0.0103
Brugia malayi Serotonin receptor 0.0007 0.001 0.001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0007 0.001 0.001
Echinococcus multilocularis neuropeptide Y receptor 0.0007 0.001 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0007 0.001 0.0011
Onchocerca volvulus 0.0029 0.0103 0.0115
Echinococcus multilocularis allatostatin A receptor 0.0007 0.001 0.0011
Schistosoma mansoni cpg binding protein 0.0037 0.0137 0.0153
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.001 0.0011
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0007 0.001 0.0011
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0119 0.0489 0.0489
Echinococcus multilocularis neuropeptide FF receptor 2 0.0007 0.001 0.0011
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0171 0.0171
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Echinococcus granulosus g protein coupled receptor 0.0007 0.001 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0016 0.1059
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0198 1
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Brugia malayi Muscleblind-like protein 0.018 0.0752 0.0752
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0011
Trichomonas vaginalis helicase, putative 0.0008 0.0014 0.0687
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0072 1
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.2094 0.234
Brugia malayi Patched family protein 0.0007 0.0011 0.0011
Echinococcus granulosus serotonin receptor 0.0007 0.001 0.0011
Toxoplasma gondii propionate-CoA ligase 0.0008 0.0016 0.0611
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0008 0.0016 0.1059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0175 0.0195
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0017 0.0019
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.4171 0.4661
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0489 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0016 0.0935
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0017 0.0019
Brugia malayi hypothetical protein 0.0007 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Onchocerca volvulus 0.0007 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0016 0.0935
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0198 0.0222
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0007 0.001 0.0011
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0489 0.0546
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0067 0.4411
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0175 0.0195
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0007 0.0011 0.0727
Loa Loa (eye worm) hypothetical protein 0.0008 0.0016 0.0016
Loa Loa (eye worm) patched family protein 0.0007 0.0011 0.0011
Schistosoma mansoni amine GPCR 0.0007 0.001 0.0011
Brugia malayi Myosin head containing protein 0.0007 0.0011 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0103 0.6
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.001
Brugia malayi Serotonin receptor 0.0456 0.1931 0.1931
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0016 0.0016

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1.122 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.299 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) = 2.2387 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.5918 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 3.3808 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 19.9526 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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