Detailed information for compound 145620

Basic information

Technical information
  • TDR Targets ID: 145620
  • Name: (1S,2S)-4-aminocyclopentane-1,2,4-tricarboxyl ic acid
  • MW: 217.176 | Formula: C8H11NO6
  • H donors: 4 H acceptors: 6 LogP: -3.99 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)[C@H]1CC(C[C@@H]1C(=O)O)(N)C(=O)O
  • InChi: 1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4-/m0/s1
  • InChiKey: FERIKTBTNCSGJS-IMJSIDKUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (1S,2S)-4-azanylcyclopentane-1,2,4-tricarboxylic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glutamate receptor, metabotropic 4 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) Get druggable targets OG5_127095 All targets in OG5_127095
Schistosoma japonicum ko:K04606 glutamate receptor, metabotropic 3, putative Get druggable targets OG5_127095 All targets in OG5_127095
Echinococcus granulosus metabotropic glutamate receptor 5 Get druggable targets OG5_127095 All targets in OG5_127095
Brugia malayi Metabotropic glutamate receptor precursor. Get druggable targets OG5_127095 All targets in OG5_127095
Echinococcus multilocularis metabotropic glutamate receptor 2 Get druggable targets OG5_127095 All targets in OG5_127095
Schistosoma mansoni metabotropic glutamate receptor Get druggable targets OG5_127095 All targets in OG5_127095
Schistosoma japonicum hypothetical protein Get druggable targets OG5_127095 All targets in OG5_127095
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127095 All targets in OG5_127095
Echinococcus granulosus metabotropic glutamate receptor 2 Get druggable targets OG5_127095 All targets in OG5_127095
Loa Loa (eye worm) glutamate receptor Get druggable targets OG5_127095 All targets in OG5_127095
Schistosoma japonicum Metabotropic glutamate receptor precursor, putative Get druggable targets OG5_127095 All targets in OG5_127095
Echinococcus multilocularis metabotropic glutamate receptor 5 Get druggable targets OG5_127095 All targets in OG5_127095
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative Get druggable targets OG5_127095 All targets in OG5_127095
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0372 0.1895 0.1882
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0037 0.0021
Loa Loa (eye worm) hypothetical protein 0.0209 0.1028 0.1014
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0209 0.1028 0.1014
Loa Loa (eye worm) hypothetical protein 0.0209 0.1028 0.1014
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0034 0.2411
Schistosoma mansoni paired box protein pax-1-related 0.0036 0.0107 0.014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0372 0.1895 0.2145
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0209 0.1028 0.1014
Mycobacterium ulcerans thioesterase TesA 0.0021 0.0025 0.2064
Echinococcus granulosus rab protein 3 0.0071 0.0289 0.0312
Brugia malayi 'Paired box' domain containing protein 0.0036 0.0107 0.0091
Echinococcus multilocularis serotonin transporter 0.1234 0.648 0.7428
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0057 0.0216 0.4441
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0037 0.0024
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0023 0.0036 0.0023
Schistosoma mansoni ap endonuclease 0.0023 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.002
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0025 0.0047 0.3628
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0034 0.0021
Schistosoma mansoni hypothetical protein 0.0274 0.1373 0.2099
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.01 0.0443 0.0491
Loa Loa (eye worm) hypothetical protein 0.0209 0.1028 0.1014
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0037 0.0024
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0209 0.1028 0.1566
Brugia malayi RAB, member of RAS oncogene family-like 5 0.0071 0.0289 0.0274
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0025 0.0047 0.4065
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0209 0.1028 0.1155
Trypanosoma brucei polo-like protein kinase 0.01 0.0443 1
Brugia malayi Cytochrome P450 family protein 0.0055 0.0204 0.0189
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0246 0.0356
Echinococcus multilocularis Smad4 0.0025 0.0045 0.0034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0372 0.1895 0.2145
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.004 0.0028
Brugia malayi Protein kinase domain containing protein 0.1654 0.8719 0.8717
Loa Loa (eye worm) hypothetical protein 0.0036 0.0107 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0021
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.002 0.0021 0.172
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.0024 0.0234
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0046 0.0157 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0037 0.0057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0372 0.1895 0.2907
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0037 0.0024
Schistosoma mansoni smad1 5 8 and 0.0025 0.0045 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0037 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0037 0.0057
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0046
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0301 0.1516 0.1723
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0127 0.0589 0.0654
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0045 0.0029
Onchocerca volvulus Poor gastrulation protein homolog 0.004 0.0125 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0037 0.0057
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0036 0.0023
Echinococcus multilocularis sodium and chloride dependent glycine 0.0209 0.1028 0.1163
Echinococcus granulosus paired box protein pax 6 0.0036 0.0107 0.0104
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0222 0.1093 0.1078
Brugia malayi hypothetical protein 0.0023 0.0037 0.0021
Giardia lamblia Kinase, PLK 0.01 0.0443 1
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0443 1
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.004 0.0125 0.0109
Entamoeba histolytica DNA topoisomerase II, putative 0.0063 0.025 0.5269
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0209 0.1028 0.1014
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0209 0.1028 0.1155
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.01 0.0443 0.0428
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0289 0.6232
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0025 0.0047 0.4065
Schistosoma mansoni metabotropic glutamate receptor 0.0205 0.1004 0.1528
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.004 0.0028
Leishmania major DNA topoisomerase ii 0.0057 0.0216 0.4441
Loa Loa (eye worm) hypothetical protein 0.0071 0.0289 0.0274
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0047 0.4065
Brugia malayi metabotropic GABA-B receptor subtype 2 0.004 0.0125 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0138 0.0122
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0021 0.0024 0.1425
Loa Loa (eye worm) hypothetical protein 0.1234 0.648 0.6475
Brugia malayi Latrophilin receptor protein 2 0.0127 0.0589 0.0574
Entamoeba histolytica hypothetical protein 0.0023 0.0037 0.0057
Loa Loa (eye worm) hypothetical protein 0.0053 0.0197 0.0181
Plasmodium falciparum transporter, putative 0.0209 0.1028 1
Chlamydia trachomatis DNA gyrase subunit B 0.0034 0.0096 0.0716
Echinococcus multilocularis beta adrenergic receptor kinase 0.0028 0.0062 0.0052
Toxoplasma gondii DNA topoisomerase 2, putative 0.0063 0.025 0.2429
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0209 0.1028 0.1566
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0037 0.0021
Mycobacterium tuberculosis Probable thioesterase TesA 0.0021 0.0025 0.1481
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0037 0.0024
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0443 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0107 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0289 0.6232
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0036 0.002
Loa Loa (eye worm) hypothetical protein 0.0209 0.1028 0.1014
Echinococcus multilocularis paired box protein pax 6 0.0036 0.0107 0.0104
Loa Loa (eye worm) pax transcription factor protein 2 0.1895 1 1
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0036 0.002
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0037 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0187 0.3745
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0062 0.0071
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0197 0.3974
Echinococcus multilocularis GPCR, family 2 0.0127 0.0589 0.0658
Brugia malayi MH1 domain containing protein 0.0025 0.0045 0.0029
Schistosoma mansoni hypothetical protein 0.004 0.0125 0.0168
Schistosoma mansoni sodium/chloride dependent transporter 0.0209 0.1028 0.1566
Echinococcus multilocularis tyrosine kinase 0.0023 0.0036 0.0023
Onchocerca volvulus 0.0209 0.1028 0.1014
Onchocerca volvulus Fatty acid synthase homolog 0.0045 0.0154 0.0138
Brugia malayi TAR-binding protein 0.0063 0.0246 0.0231
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0045 0.0034
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0037 0.0024
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0037 0.0113 1
Echinococcus multilocularis GPCR, family 3, C terminal 0.004 0.0125 0.0125
Brugia malayi Metabotropic glutamate receptor precursor. 0.0244 0.1215 0.1201
Schistosoma mansoni ap endonuclease 0.0023 0.0034 0.0029
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0197 0.3974
Onchocerca volvulus 0.1234 0.648 0.6475
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0037 0.0032
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0023 0.0036 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.002
Echinococcus granulosus paired box protein pax 1 0.0036 0.0107 0.0104
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1234 0.648 1
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.005 0.0178 0.3512
Brugia malayi hypothetical protein 0.0053 0.0197 0.0181
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0046 0.0157 0.0142
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0037 0.0032
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0127 0.0589 0.0574
Schistosoma mansoni hypothetical protein 0.0127 0.0589 0.0886
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0021
Echinococcus granulosus tar DNA binding protein 0.0063 0.0246 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0443 0.0661
Loa Loa (eye worm) hypothetical protein 0.0071 0.0289 0.0274
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0021
Mycobacterium ulcerans DNA gyrase subunit B 0.0021 0.0024 0.2013
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0036 0.0023
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0024 0.0043 0.3234
Trypanosoma brucei Rab-like 5, small G protein 0.0071 0.0289 0.6232
Echinococcus multilocularis GTP binding protein Parf 0.0071 0.0289 0.0314
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0037 0.0032
Toxoplasma gondii hypothetical protein 0.0209 0.1028 1
Toxoplasma gondii type I fatty acid synthase, putative 0.0027 0.0055 0.0537
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0037 0.0024
Loa Loa (eye worm) MH2 domain-containing protein 0.0363 0.1846 0.1833
Echinococcus granulosus metabotropic glutamate receptor 2 0.0205 0.1004 0.1127
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0037 0.0024
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0037 0.0032
Loa Loa (eye worm) hypothetical protein 0.0401 0.2048 0.2035
Plasmodium vivax ras-related protein Rab-5A, putative 0.0071 0.0289 0.264
Brugia malayi 'Paired box' domain containing protein 0.0036 0.0107 0.0091
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0372 0.1895 0.2907
Loa Loa (eye worm) paired box protein 0.0036 0.0107 0.0091
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0037 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0246 0.0356
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0048 0.0166 0.0151
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0028 0.0062 0.0046
Trypanosoma brucei DNA topoisomerase ii 0.005 0.0178 0.3512
Echinococcus multilocularis paired box protein pax 6 0.0036 0.0107 0.0104
Echinococcus granulosus GTP binding protein Parf 0.0071 0.0289 0.0312
Loa Loa (eye worm) hypothetical protein 0.0071 0.0289 0.0274
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0063 0.025 0.0234
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0209 0.1028 0.1566
Loa Loa (eye worm) Smad1 0.0025 0.0045 0.0029
Schistosoma mansoni hypothetical protein 0.0024 0.004 0.0038
Onchocerca volvulus 0.0209 0.1028 0.1014
Plasmodium vivax amine transporter, putative 0.0209 0.1028 1
Echinococcus granulosus serotonin transporter 0.1234 0.648 0.7377
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0034 0.2931
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.002 0.0021 0.172
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0023 0.0036 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0037 0.0057
Echinococcus multilocularis sodium and chloride dependent glycine 0.0209 0.1028 0.1163
Schistosoma mansoni sodium/chloride dependent transporter 0.1234 0.648 1
Loa Loa (eye worm) hypothetical protein 0.0127 0.0589 0.0574
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0372 0.1895 0.2159
Schistosoma mansoni DNA topoisomerase II 0.0063 0.025 0.0362
Loa Loa (eye worm) glutamate receptor 0.0096 0.0425 0.041
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0127 0.0589 0.0658
Schistosoma mansoni sodium/chloride dependent transporter 0.0214 0.1053 0.1604
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0047 0.4065
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0046
Entamoeba histolytica hypothetical protein 0.0023 0.0036 0.0036
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0023 0.0036 0.0023
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0034 0.0016
Onchocerca volvulus 0.0023 0.0036 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0021
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.01 0.0443 1
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0046 0.0157 0.0142
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0038 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0021
Brugia malayi MH1 domain containing protein 0.0025 0.0045 0.0029
Trichomonas vaginalis DNA topoisomerase II, putative 0.0063 0.025 0.5269
Loa Loa (eye worm) hypothetical protein 0.0209 0.1028 0.1014
Mycobacterium ulcerans polyketide synthase 0.0027 0.0055 0.481
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0037 0.0032
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0027 0.0055 0.481
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0246 0.0231
Brugia malayi Calcitonin receptor-like protein seb-1 0.0401 0.2048 0.2035
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0209 0.1028 1
Echinococcus multilocularis rab protein 3 0.0071 0.0289 0.0314
Onchocerca volvulus 0.0036 0.0107 0.0091
Toxoplasma gondii type I fatty acid synthase, putative 0.0018 0.0008 0.0082
Echinococcus granulosus smad 0.0025 0.0045 0.0033
Brugia malayi PXA domain containing protein 0.0023 0.0037 0.0021
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0047 0.3628
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0209 0.1028 0.1163
Loa Loa (eye worm) hypothetical protein 0.0209 0.1028 0.1014
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0443 1
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0209 0.1028 0.1163
Echinococcus granulosus sodium and chloride dependent glycine 0.0209 0.1028 0.1155
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0289 0.6232
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0443 1
Echinococcus multilocularis paired box protein pax 1 0.0036 0.0107 0.0104
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0037 0.0024
Brugia malayi paired box protein 0.0036 0.0107 0.0091
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0037 0.0021
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0037 0.0057
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0209 0.1028 0.1566
Echinococcus granulosus Smad4 0.0025 0.0045 0.0033
Brugia malayi hypothetical protein 0.0209 0.1028 0.1014
Leishmania major hypothetical protein, conserved 0.0071 0.0289 0.6232
Schistosoma mansoni paired box protein pax-6 0.0036 0.0107 0.014
Echinococcus granulosus GPCR family 2 0.0127 0.0589 0.0654
Onchocerca volvulus 0.0023 0.0036 0.002
Plasmodium falciparum DNA topoisomerase 2 0.0063 0.025 0.2248
Schistosoma mansoni hypothetical protein 0.0071 0.0289 0.0423
Echinococcus multilocularis expressed protein 0.0451 0.2313 0.2639
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0037 0.0032
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0372 0.1895 0.1882
Brugia malayi PXA domain containing protein 0.0023 0.0037 0.0021
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0047 0.4065
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0037 0.0113 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.01 0.0443 0.0428
Brugia malayi Ras-related protein ypt4 0.0071 0.0289 0.0274
Onchocerca volvulus 0.0071 0.0289 0.0274
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0047 0.4065
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0037 0.0024
Brugia malayi Probable DNA topoisomerase II 0.0063 0.025 0.0234
Toxoplasma gondii hypothetical protein 0.0209 0.1028 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0209 0.1028 0.1014
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0037 0.0032
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0037 0.0024
Brugia malayi 'Paired box' domain containing protein 0.0036 0.0107 0.0091
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0197 0.172
Echinococcus multilocularis receptor type guanylyl cyclase 0.0023 0.0036 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0246 0.0356
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0036 0.0023
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0209 0.1028 0.1155
Schistosoma mansoni protein kinase 0.0023 0.0036 0.0031
Trypanosoma cruzi DNA topoisomerase II, putative 0.0057 0.0216 0.4441
Echinococcus granulosus sodium and chloride dependent glycine 0.0209 0.1028 0.1155
Mycobacterium leprae Polyketide synthase Pks13 0.0037 0.0113 1
Leishmania major hypothetical protein, conserved 0.0053 0.0197 0.3974
Echinococcus granulosus beta-adrenergic receptor kinase 0.0028 0.0062 0.0052
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0037 0.0032
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0034 1
Entamoeba histolytica hypothetical protein 0.0023 0.0037 0.0057
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0027 0.0055 0.481
Plasmodium vivax hypothetical protein, conserved 0.0209 0.1028 1
Onchocerca volvulus 0.0209 0.1028 0.1014
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0197 0.3974
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0063 0.0247 0.0232
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.005 0.0178 0.3512
Loa Loa (eye worm) glutamate receptor 0.0244 0.1215 0.1201
Schistosoma mansoni smad1 5 8 and 0.0025 0.0045 0.0045
Loa Loa (eye worm) solute carrier family 6 member 4 0.1234 0.648 0.6475
Brugia malayi MH2 domain containing protein 0.0363 0.1846 0.1833
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0246 0.0356
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0209 0.1028 0.1566
Brugia malayi Gooseberry protein 0.0036 0.0107 0.0091
Brugia malayi latrophilin 2 splice variant baaae 0.0274 0.1373 0.1359
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0027 0.0055 0.4429
Schistosoma mansoni paired box protein pax-6 0.0036 0.0107 0.014
Brugia malayi vab-3 gene. 0.0036 0.0107 0.0091
Plasmodium falciparum amino acid transporter, putative 0.0209 0.1028 1
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0037 0.0032
Echinococcus granulosus metabotropic glutamate receptor 5 0.0301 0.1516 0.1712
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0037 0.0024
Echinococcus granulosus GPCR family 3 C terminal 0.004 0.0125 0.0124
Trichomonas vaginalis GTP binding protein rare7l, putative 0.0071 0.0289 0.6232
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.1665 0.8779 1
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0246 0.0356
Brugia malayi RNA binding protein 0.0063 0.0246 0.0231
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.002
Plasmodium falciparum ras-related protein Rab-5A 0.0071 0.0289 0.264
Echinococcus granulosus glutamate receptor 2 0.0023 0.0036 0.0023
Echinococcus multilocularis paired box protein pax 6 0.0036 0.0107 0.0104
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0021 0.0023 0.1281
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0209 0.1028 0.1566
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.002
Brugia malayi hypothetical protein 0.0034 0.0096 0.0081
Schistosoma mansoni smad1 5 8 and 0.0025 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0021
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0037 0.0024
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0063 0.025 0.0269
Loa Loa (eye worm) TOPoisomerase family member 0.0063 0.025 0.0234
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.002
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0037 0.0024
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0034 0.0102
Mycobacterium ulcerans thioesterase 0.0021 0.0025 0.2064
Loa Loa (eye worm) hypothetical protein 0.0036 0.0107 0.0091
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0109
Toxoplasma gondii exonuclease III APE 0.0023 0.0034 0.0333
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0209 0.1028 0.1566
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0209 0.1028 0.1155
Echinococcus granulosus nmda type glutamate receptor 0.0023 0.0036 0.0023
Giardia lamblia DNA topoisomerase II 0.006 0.0235 0.4906
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0443 1
Schistosoma mansoni metabotropic glutamate receptor 0.0119 0.0548 0.0823
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0372 0.1895 0.2907
Trypanosoma cruzi Rab-like 5, small G protein 0.0071 0.0289 0.6232
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0246 0.0231
Brugia malayi paired box pox-meso protein 0.0036 0.0107 0.0091
Echinococcus granulosus receptor type guanylyl cyclase 0.0023 0.0036 0.0023
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0209 0.1028 0.1566
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0037 0.0024
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0027 0.0055 0.481
Schistosoma mansoni smad 0.0025 0.0045 0.0045
Trypanosoma cruzi DNA topoisomerase II, putative 0.0057 0.0216 0.4441
Echinococcus granulosus paired box gene 3/7 (eyeless, eyegone, twin of eyeless) 0.0036 0.0107 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0443 1
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0062 0.0071
Schistosoma mansoni tyrosine kinase 0.0023 0.0036 0.0031
Echinococcus granulosus paired box protein pax 6 0.0036 0.0107 0.0104
Brugia malayi MH2 domain containing protein 0.0025 0.0045 0.0029
Schistosoma mansoni sodium-dependent amino acid transporter 0.0209 0.1028 0.1566
Onchocerca volvulus 0.0044 0.0146 0.013
Loa Loa (eye worm) hypothetical protein 0.0042 0.0139 0.0123
Schistosoma mansoni Smad4 0.0025 0.0045 0.0045
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0063 0.025 0.0267
Schistosoma mansoni hypothetical protein 0.0127 0.0589 0.0886
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.002 0.0021 0.172
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0023 0.0036 0.002
Entamoeba histolytica hypothetical protein 0.0071 0.0289 0.6232
Brugia malayi metabotropic glutamate receptor type 2 0.0119 0.0548 0.0533
Loa Loa (eye worm) serotonin transporter b 0.1234 0.648 0.6475
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0443 1
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0205 0.1004 0.1135
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0025 0.0047 0.3628
Brugia malayi hypothetical protein 0.0023 0.0036 0.002
Echinococcus granulosus expressed protein 0.0451 0.2313 0.2621
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0021 0.0025 0.2064
Onchocerca volvulus Retinal homeobox protein Rx homolog 0.0036 0.0107 0.0091
Leishmania major hypothetical protein, conserved 0.0071 0.0289 0.6232
Loa Loa (eye worm) hypothetical protein 0.0301 0.1516 0.1502
Treponema pallidum sodium- and chloride- dependent transporter 0.1234 0.648 1
Schistosoma mansoni paired box protein pax-6 0.0036 0.0107 0.014
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0127 0.0589 0.0654
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0034 0.0102
Echinococcus multilocularis nmda type glutamate receptor 0.0023 0.0036 0.0023
Schistosoma mansoni hypothetical protein 0.0127 0.0589 0.0886
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0045 0.0033
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0027 0.0055 0.4429
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0187 0.3745
Loa Loa (eye worm) transcription factor SMAD2 0.0363 0.1846 0.1833
Loa Loa (eye worm) hypothetical protein 0.1234 0.648 0.6475
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0036 0.0023
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0127 0.0589 0.0658
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0024 0.0043 0.3234
Schistosoma mansoni hypothetical protein 0.0127 0.0589 0.0886
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0278 0.1393 0.2131
Schistosoma mansoni kinase 0.0053 0.0194 0.0276
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0036 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0372 0.1895 0.2159
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0197 0.172
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0063 0.0247 0.0232
Plasmodium vivax DNA topoisomerase II, putative 0.0063 0.025 0.2248
Echinococcus granulosus glutamate receptor 2 0.0023 0.0036 0.0023
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0034 0.0021
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0036 0.002
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0209 0.1028 0.1163
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0027 0.0055 0.481
Echinococcus multilocularis ras-related protein rab-5 0.0071 0.0289 0.0314
Onchocerca volvulus 0.0023 0.0038 0.0022
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0246 0.0231
Loa Loa (eye worm) latrophilin receptor protein 2 0.0127 0.0589 0.0574
Onchocerca volvulus 0.0036 0.0107 0.0091
Brugia malayi Smad1 0.0025 0.0045 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0062 0.0071
Schistosoma mansoni glutamate receptor NMDA 0.0023 0.0036 0.0031
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0023 0.0036 0.002
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0037 0.0021
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0037 0.0024
Loa Loa (eye worm) hypothetical protein 0.0036 0.0107 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0289 0.6232
Loa Loa (eye worm) hypothetical protein 0.1234 0.648 0.6475
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0037 0.0024
Echinococcus granulosus atrial natriuretic peptide receptor 0.0023 0.0036 0.0023
Mycobacterium ulcerans polyketide synthase Pks13 0.0037 0.0113 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0197 0.172
Trypanosoma cruzi extracellular receptor, putative 0.0023 0.0036 0.0036
Entamoeba histolytica hypothetical protein 0.0071 0.0289 0.6232
Loa Loa (eye worm) fatty acid synthase 0.0025 0.0045 0.0029
Loa Loa (eye worm) vab-3 0.0036 0.0107 0.0091
Schistosoma mansoni tyrosine kinase 0.0023 0.0036 0.0031
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0034 0.0018
Brugia malayi serine/threonine-protein kinase plk-2 0.01 0.0443 0.0428
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0204 0.0189
Brugia malayi Receptor family ligand binding region containing protein 0.0063 0.0247 0.0232
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0209 0.1028 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0036 0.0023
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0063 0.025 0.0234
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0045 0.0033
Mycobacterium leprae Probable polyketide synthase Pks1 0.0027 0.0055 0.481
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0209 0.1028 0.1014
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0036 0.0023
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.0443 1
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.1654 0.8719 1
Leishmania major extracellular receptor, putative 0.0023 0.0036 0.0036
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0037 0.0021
Echinococcus multilocularis smad 0.0025 0.0045 0.0034
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0037 0.0021
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0246 0.0265
Loa Loa (eye worm) RNA binding protein 0.0063 0.0246 0.0231
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0036 0.0023
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0057 0.0216 0.4441
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0209 0.1028 1
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0443 1
Onchocerca volvulus 0.1895 1 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0401 0.2048 0.2035
Loa Loa (eye worm) hypothetical protein 0.0063 0.0247 0.0232
Brugia malayi Guanylyl cyclase protein 23 0.0023 0.0036 0.002
Leishmania major mitochondrial DNA topoisomerase II 0.005 0.0178 0.3512
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0443 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0209 0.1028 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0028 0.0062 0.0046
Entamoeba histolytica hypothetical protein 0.0023 0.0037 0.0057
Loa Loa (eye worm) hypothetical protein 0.0209 0.1028 0.1014
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0036 0.0023
Echinococcus granulosus tyrosine kinase 0.0023 0.0036 0.0023
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0071 0.0289 0.0274
Echinococcus granulosus serine:threonine protein kinase PLK1 0.01 0.0443 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0037 0.0057
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0045 0.0034
Mycobacterium ulcerans polyketide synthase 0.0025 0.0047 0.4065
Loa Loa (eye worm) hypothetical protein 0.0274 0.1373 0.1359
Brugia malayi hypothetical protein 0.0023 0.0037 0.0021
Trichomonas vaginalis hypothetical protein 0.0071 0.0289 0.6232
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0023 0.0038 0.2782
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0028 0.0062 0.0046
Loa Loa (eye worm) hypothetical protein 0.0042 0.0139 0.0123
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0209 0.1028 0.1014
Loa Loa (eye worm) norepinephrine transporter 0.1234 0.648 0.6475
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0401 0.2048 0.2035
Loa Loa (eye worm) TKL/LRRK protein kinase 0.1654 0.8719 0.8717
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0025 0.0047 0.0031
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0027 0.0055 0.4429
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0037 0.0032
Brugia malayi MH2 domain containing protein 0.0025 0.0045 0.0029
Brugia malayi hypothetical protein 0.0071 0.0289 0.0274
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0038 0.0022
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0034 0.0018
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0037 0.0024
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0037 0.0021
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0197 0.1914
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0045 0.0029
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1234 0.648 0.6475

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) uM Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation; No effect at 1 mM ChEMBL. 9301676
EC50 (functional) NE 0 uM Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation; No effect at 1 mM ChEMBL. 9301676
EC50 (functional) NE 0 uM Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation; No effect at 1 mM ChEMBL. 9301676
EC50 (functional) = 8.8 uM Agonist activity against Metabotropic glutamate receptor 4 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation ChEMBL. 9301676
EC50 (functional) = 8.8 uM Agonist activity against Metabotropic glutamate receptor 4 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation ChEMBL. 9301676
EC50 (functional) < 100 uM Stimulation of [3H]-phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 coexpressed with Gqi9 protein in HEK 293 cells; Active ChEMBL. 15801843
EC50 (functional) < 100 uM Stimulation of [3H]-phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 coexpressed with Gqi9 protein in HEK 293 cells; Active ChEMBL. 15801843
Kb (functional) uM Antagonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation; Not determined ChEMBL. 9301676
KB (functional) 0 uM Antagonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation; Not determined ChEMBL. 9301676
KB (functional) 0 uM Antagonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation; Not determined ChEMBL. 9301676
Ki (functional) = 8.8 uM Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4) ChEMBL. 10893301
Ki (functional) = 8.8 uM Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4) ChEMBL. 10893301
Ki (functional) > 1000 uM Agonist potency against cloned human metabotropic glutamate receptor 1 ChEMBL. 10893301
Ki (functional) > 1000 uM Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2). ChEMBL. 10893301
Ki (functional) > 1000 uM Agonist potency against cloned human metabotropic glutamate receptor 1 ChEMBL. 10893301
Ki (functional) > 1000 uM Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2). ChEMBL. 10893301

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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