Detailed information for compound 1591591

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 510.59 | Formula: C28H30N8O2
  • H donors: 3 H acceptors: 6 LogP: 2.51 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(CC(N)(C)C)N[C@@H]1CCc2c(N(C1=O)Cc1ccc(cc1)c1cccnc1c1n[nH]nn1)cccc2
  • InChi: 1S/C28H30N8O2/c1-28(2,29)16-24(37)31-22-14-13-20-6-3-4-8-23(20)36(27(22)38)17-18-9-11-19(12-10-18)21-7-5-15-30-25(21)26-32-34-35-33-26/h3-12,15,22H,13-14,16-17,29H2,1-2H3,(H,31,37)(H,32,33,34,35)/t22-/m1/s1
  • InChiKey: SAKKNUFZKWSMCR-JOCHJYFZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0026 0.0018 0.0027
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0101 0.016
Schistosoma mansoni intermediate filament proteins 0.007 0.0276 0.0277
Loa Loa (eye worm) hypothetical protein 0.0154 0.0775 0.1149
Brugia malayi hypothetical protein 0.0201 0.1053 0.157
Brugia malayi 6-phosphofructokinase 0.0108 0.0501 0.0733
Echinococcus granulosus nuclear receptor nhr 48 0.0046 0.0132 0.0122
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0043 0.0051
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.007 0.0276 0.0392
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0038
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0079 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0012 0.0014
Echinococcus granulosus malate dehydrogenase 0.084 0.4837 0.5172
Trypanosoma cruzi mitochondrial malate dehydrogenase, putative 0.084 0.4837 0.9238
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0046 0.0132 0.0122
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0501 0.0927
Brugia malayi beta-lactamase family protein 0.0031 0.0043 0.0038
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0057 0.0197 0.0192
Schistosoma mansoni retinoic acid receptor RXR 0.0097 0.0435 0.0448
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0029 0.0031 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0034 0.004
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0087 0.0104
Echinococcus granulosus malate dehydrogenase 0.084 0.4837 0.5172
Onchocerca volvulus 0.0046 0.0132 0.0358
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0097 0.0435 0.0418
Brugia malayi Muscleblind-like protein 0.0154 0.0775 0.1149
Mycobacterium tuberculosis Conserved protein 0.0031 0.0043 0.0022
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0041 0.0104 0.0131
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Echinococcus multilocularis lactate dehydrogenase a 0.114 0.6612 0.6606
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0029 0.0031 0.0025
Echinococcus multilocularis malate dehydrogenase 0.084 0.4837 0.4828
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0097 0.0435 0.0448
Mycobacterium leprae PROBABLE MALATE DEHYDROGENASE MDH 0.0907 0.5235 1
Schistosoma mansoni lamin 0.007 0.0276 0.0277
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0097 0.0435 0.1574
Trypanosoma brucei glycosomal malate dehydrogenase 0.084 0.4837 0.9238
Loa Loa (eye worm) hypothetical protein 0.0097 0.0435 0.0633
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Brugia malayi ecdysteroid receptor 0.0097 0.0435 0.0633
Trichomonas vaginalis malate dehydrogenase, putative 0.0661 0.3778 0.4492
Brugia malayi nuclear receptor RXR 0.0046 0.0132 0.0173
Brugia malayi nuclear hormone receptor 0.0097 0.0435 0.0633
Echinococcus granulosus tumor protein p63 0.0336 0.1851 0.1968
Onchocerca volvulus 0.0059 0.0211 0.0676
Trichomonas vaginalis sulfite reductase, putative 0.0026 0.0018 0.0021
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0101 0.0153
Schistosoma mansoni hypothetical protein 0.0057 0.0197 0.0192
Echinococcus granulosus lactate dehydrogenase protein 0.114 0.6612 0.7076
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0501 0.0558
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0043 0.0047
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0097 0.0435 0.0448
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0031 0.0025
Echinococcus granulosus L lactate dehydrogenase 0.0479 0.2695 0.2873
Plasmodium vivax malate dehydrogenase, putative 0.114 0.6612 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0132 0.0122
Brugia malayi Nuclear hormone receptor-like 1 0.0097 0.0435 0.0633
Brugia malayi Cytochrome P450 family protein 0.0067 0.026 0.0367
Leishmania major cytochrome p450-like protein 0.0029 0.0031 0.0047
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0039 0.0021
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0501 0.0733
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0012 0.0014
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0039 0.0021
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Mycobacterium ulcerans esterase/lipase LipP 0.0031 0.0043 0.0047
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0046 0.0132 0.0173
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0501 0.0558
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0043 0.0027
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0136 0.0226
Mycobacterium tuberculosis Probable hydrolase 0.0031 0.0043 0.0022
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0907 0.5235 1
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0029 0.0031 0.0025
Schistosoma mansoni RAR-like nuclear receptor 0.0097 0.0435 0.0448
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Schistosoma mansoni cytochrome P450 0.0029 0.0031 0.0014
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0031 0.0043 0.0038
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0029 0.0031 0.0025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1444 0.8411 1
Schistosoma mansoni L-lactate dehydrogenase 0.0661 0.3778 0.4035
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0179 0.0923 0.1373
Schistosoma mansoni hypothetical protein 0.0057 0.0197 0.0192
Echinococcus granulosus lamin 0.007 0.0276 0.0277
Schistosoma mansoni alpha-glucosidase 0.0148 0.0739 0.0774
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0907 0.5235 0.5226
Schistosoma mansoni hypothetical protein 0.0029 0.0031 0.0014
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0501 0.0519
Leishmania major cytochrome p450-like protein 0.0029 0.0031 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0097 0.0435 0.0633
Leishmania major malate dehydrogenase, putative 0.114 0.6612 1
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0029 0.0031 0.0047
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0097 0.0435 0.0633
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Brugia malayi hypothetical protein 0.0051 0.0164 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0012 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0087 0.0104
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0087 0.0086
Trypanosoma brucei malate dehydrogenase-related 0.0661 0.3778 0.7207
Mycobacterium ulcerans hypothetical protein 0.0031 0.0043 0.0047
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0132 0.0173
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0705 0.4038 0.7699
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0097 0.0435 0.0418
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0029 0.0031 0.0025
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0026 0.0018 0.0027
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0907 0.5235 0.6224
Trypanosoma brucei mitochondrial malate dehydrogenase 0.084 0.4837 0.9238
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0029 0.0031 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0501 0.0596
Echinococcus multilocularis GPCR, family 2 0.0057 0.0197 0.018
Echinococcus granulosus lysosomal alpha glucosidase 0.0172 0.0881 0.0926
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0097 0.0435 0.0448
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0101 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0097 0.0435 0.0633
Echinococcus granulosus FTZ F1 alpha 0.0097 0.0435 0.0448
Schistosoma mansoni microtubule-associated protein tau 0.1165 0.6762 0.7237
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0039 0.0022
Loa Loa (eye worm) hypothetical protein 0.0179 0.0923 0.1373
Echinococcus granulosus thyroid hormone receptor alpha 0.0046 0.0132 0.0122
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0034 0.0061 0.0044
Entamoeba histolytica malate dehydrogenase, putative 0.0907 0.5235 0.6209
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0051 0.0164 0.0157
Loa Loa (eye worm) hypothetical protein 0.0097 0.0435 0.0633
Leishmania major cytosolic malate dehydrogenase 0.0907 0.5235 0.7917
Echinococcus multilocularis ecdysone induced protein 78C 0.0097 0.0435 0.0418
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0059 0.0211 0.0274
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1444 0.8411 1
Schistosoma mansoni malate dehydrogenase 0.084 0.4837 0.5172
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.084 0.4837 0.9238
Echinococcus multilocularis thyroid hormone receptor alpha 0.0097 0.0435 0.0418
Chlamydia trachomatis malate dehydrogenase 0.0907 0.5235 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0034 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0087 0.0104
Brugia malayi Malate dehydrogenase, cytoplasmic 0.0907 0.5235 0.7911
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0085 0.0367 0.035
Brugia malayi 6-phosphofructokinase 0.0108 0.0501 0.0733
Trypanosoma brucei cytosolic malate dehydrogenase 0.0907 0.5235 1
Echinococcus multilocularis geminin 0.0796 0.4573 0.4564
Echinococcus multilocularis malate dehydrogenase 0.084 0.4837 0.4828
Plasmodium falciparum lactate dehydrogenase, putative 0.0661 0.3778 0.5702
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0038
Schistosoma mansoni thyroid hormone receptor 0.0097 0.0435 0.0448
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0059 0.0211 0.0194
Toxoplasma gondii lactate dehydrogenase LDH1 0.114 0.6612 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0101 0.0135
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0034 0.004
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0038 0.0083 0.0099
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1444 0.8411 1
Echinococcus granulosus cytosolic malate dehydrogenase 0.0907 0.5235 0.5598
Loa Loa (eye worm) hypothetical protein 0.0201 0.1053 0.157
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0136 0.0226
Echinococcus multilocularis microtubule associated protein 2 0.1165 0.6762 0.6756
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0029 0.0031 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0097 0.0435 0.0418
Schistosoma mansoni cpg binding protein 0.0119 0.0564 0.0586
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0031 0.0025
Brugia malayi phosphofructokinase 0.0108 0.0501 0.0733
Trichomonas vaginalis set domain proteins, putative 0.0452 0.2539 0.3019
Echinococcus granulosus intermediate filament protein 0.007 0.0276 0.0277
Toxoplasma gondii malate dehydrogenase MDH 0.114 0.6612 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0051 0.0164 0.0222
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0079 0.0061
Schistosoma mansoni L-lactate dehydrogenase 0.114 0.6612 0.7076
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0097 0.0435 0.0448
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0179 0.0923 0.1373
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0101 0.016
Giardia lamblia Fructose-bisphosphate aldolase 0.1444 0.8411 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0029 0.0031 0.0025
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0029 0.0031 0.0025
Loa Loa (eye worm) hypothetical protein 0.0051 0.0164 0.0222
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0087 0.0133
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0097 0.0435 0.0448
Echinococcus multilocularis lactate dehydrogenase a 0.114 0.6612 0.6606
Treponema pallidum fructose-bisphosphate aldolase 0.1444 0.8411 1
Brugia malayi Steroid receptor seven-up type 2 0.0097 0.0435 0.0633
Echinococcus granulosus snurportin 1 0.0306 0.1674 0.1777
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0501 0.0558
Schistosoma mansoni importin beta-1 0.0029 0.0031 0.0014
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0087 0.0064
Schistosoma mansoni cpg binding protein 0.0112 0.0526 0.0546
Mycobacterium tuberculosis Conserved protein 0.0031 0.0043 0.0022
Schistosoma mansoni hypothetical protein 0.0057 0.0197 0.0192
Plasmodium vivax lactate dehydrogenase 0.114 0.6612 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0034 0.0051
Onchocerca volvulus 0.007 0.0276 0.0935
Loa Loa (eye worm) hypothetical protein 0.0097 0.0435 0.0633
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.084 0.4837 0.9238
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0087 0.0132
Leishmania major malate dehydrogenase 0.084 0.4837 0.7316
Loa Loa (eye worm) beta-lactamase 0.0031 0.0043 0.0038
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0055 0.0184 0.0179
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0051 0.0164 0.0147
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0054
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0501 0.0733
Trypanosoma brucei cytochrome P450, putative 0.0046 0.0136 0.0226
Echinococcus multilocularis survival motor neuron protein 1 0.0201 0.1053 0.1037
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0097 0.0435 0.0448
Brugia malayi CXXC zinc finger family protein 0.0112 0.0526 0.0771
Schistosoma mansoni nuclear receptor 0.0046 0.0132 0.0122
Entamoeba histolytica malate dehydrogenase, putative 0.114 0.6612 0.7853
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0097 0.0435 0.0633
Schistosoma mansoni survival motor neuron protein 0.0041 0.0104 0.0093
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0097 0.0435 0.0448
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0031 0.0043 0.0022
Schistosoma mansoni hypothetical protein 0.0306 0.1674 0.1777
Echinococcus granulosus L lactate dehydrogenase B chain 0.114 0.6612 0.7076
Loa Loa (eye worm) malate dehydrogenase 0.0907 0.5235 0.7911
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0211 0.0208
Schistosoma mansoni ap endonuclease 0.0041 0.0101 0.0089
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0077 0.0089
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0087 0.0104
Leishmania major glycosomal malate dehydrogenase 0.084 0.4837 0.7316
Entamoeba histolytica malate dehydrogenase,cytoplasmic, putative 0.0907 0.5235 0.6209
Wolbachia endosymbiont of Brugia malayi malate dehydrogenase 0.114 0.6612 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0031 0.0043 0.0027
Loa Loa (eye worm) DR-78 0.0046 0.0132 0.0173
Brugia malayi ecdysone receptor 0.0046 0.0132 0.0173
Brugia malayi steroid hormone receptor 0.0097 0.0435 0.0633
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0031 0.0043 0.0047
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0038
Brugia malayi hypothetical protein 0.0046 0.0132 0.0173
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0097 0.0435 0.0418
Loa Loa (eye worm) hypothetical protein 0.0097 0.0435 0.0633
Echinococcus multilocularis tumor protein p63 0.0336 0.1851 0.1837
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0101 0.016
Plasmodium vivax lactate/malate dehydrogenase, putative 0.0661 0.3778 0.5714
Brugia malayi nuclear hormone receptor family member nhr-6 0.0046 0.0132 0.0173
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1444 0.8411 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0132 0.0114
Echinococcus granulosus importin subunit beta 1 0.0029 0.0031 0.0014
Leishmania major cytochrome p450-like protein 0.0046 0.0136 0.0206
Brugia malayi hypothetical protein 0.0051 0.0164 0.0222
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0034 0.004
Echinococcus granulosus cytochrome P450 2K1 0.0029 0.0031 0.0014
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0097 0.0435 0.0418
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0043 0.0064
Echinococcus multilocularis FTZ F1 alpha 0.0097 0.0435 0.0418
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0034 0.004
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0029 0.0031 0.0025
Echinococcus granulosus GPCR family 2 0.0057 0.0197 0.0192
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0097 0.0435 0.0448
Echinococcus multilocularis beta LACTamase domain containing family member 0.0031 0.0043 0.0025
Brugia malayi Intermediate filament tail domain containing protein 0.007 0.0276 0.0392
Schistosoma mansoni glutaminase 0.0589 0.335 0.3576
Loa Loa (eye worm) latrophilin receptor protein 2 0.0057 0.0197 0.0272
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0132 0.0122
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0097 0.0435 0.0448
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0101 0.0153
Schistosoma mansoni malate dehydrogenase 0.0907 0.5235 0.5598
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0101 0.012
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0172 0.0881 0.1309
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0164 0.0157
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1444 0.8411 1
Onchocerca volvulus 0.0046 0.0132 0.0358
Loa Loa (eye worm) malate dehydrogenase 0.084 0.4837 0.7308
Onchocerca volvulus 0.0452 0.2539 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0034 0.0051
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0132 0.0122
Mycobacterium leprae conserved hypothetical protein 0.0031 0.0043 0.0022
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0087 0.0075
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0101 0.008
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0501 0.0519
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0043 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0097 0.0435 0.0633
Schistosoma mansoni lamin 0.007 0.0276 0.0277
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0398 0.2216 0.3333
Trypanosoma cruzi malate dehydrogenase, putative 0.084 0.4837 0.9238
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0097 0.0435 0.0448
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0101 0.0126
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0029 0.0031 0.0025
Brugia malayi latrophilin 2 splice variant baaae 0.0123 0.0587 0.0863
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0046 0.0132 0.0122
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0057 0.0197 0.0192
Schistosoma mansoni zinc finger protein 0.0046 0.0132 0.0122
Onchocerca volvulus 0.0041 0.0104 0.0247
Brugia malayi Cytochrome P450 family protein 0.0046 0.0136 0.0179
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0087 0.007
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0085 0.0367 0.0529
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0046 0.0132 0.0173
Schistosoma mansoni hypothetical protein 0.0123 0.0587 0.0611
Plasmodium falciparum malate dehydrogenase 0.114 0.6612 1
Brugia malayi nuclear receptor NHR-67 0.0046 0.0132 0.0173
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0101 0.0126
Mycobacterium ulcerans malate dehydrogenase 0.0907 0.5235 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0012 0.0014
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0132 0.0358
Brugia malayi beta-lactamase family protein 0.0031 0.0043 0.0038
Echinococcus multilocularis muscleblind protein 0.0154 0.0775 0.0759
Schistosoma mansoni thyroid hormone receptor 0.0097 0.0435 0.0448
Brugia malayi hypothetical protein 0.0046 0.0132 0.0173
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0085 0.0367 0.0375
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0881 0.0865
Echinococcus granulosus dnaJ subfamily B 0.16 0.9337 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0097 0.0435 0.0633
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0211 0.0208
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0012 0.0014
Schistosoma mansoni hypothetical protein 0.16 0.9337 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0031 0.0025
Echinococcus multilocularis 0.0029 0.0031 0.0013
Loa Loa (eye worm) hypothetical protein 0.0097 0.0435 0.0633
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0087 0.0064
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0501 0.0484
Echinococcus multilocularis lactate dehydrogenase protein 0.114 0.6612 0.6606
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Mycobacterium leprae Probable lipase LipE 0.0031 0.0043 0.0022
Brugia malayi photoreceptor-specific nuclear receptor 0.0097 0.0435 0.0633
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0012 0.0014
Echinococcus multilocularis muscleblind protein 1 0.0154 0.0775 0.0759
Plasmodium falciparum L-lactate dehydrogenase 0.114 0.6612 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0039 0.0022
Toxoplasma gondii histone lysine methyltransferase SET1 0.0215 0.1134 0.1676
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0085 0.0367 0.0375
Onchocerca volvulus 0.0097 0.0435 0.1574
Echinococcus multilocularis L lactate dehydrogenase B chain 0.114 0.6612 0.6606
Trypanosoma cruzi malate dehydrogenase, putative 0.0661 0.3778 0.7207
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0705 0.4038 0.7699
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0907 0.5235 1
Mycobacterium tuberculosis Probable malate dehydrogenase Mdh 0.0907 0.5235 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0031 0.0043 0.0022
Brugia malayi cytochrome P450 0.0029 0.0031 0.002
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0306 0.1674 0.2512
Schistosoma mansoni nuclear receptor nhr-48 0.0046 0.0132 0.0122
Brugia malayi intermediate filament protein 0.007 0.0276 0.0392
Brugia malayi nuclear receptor NHR-88 0.0097 0.0435 0.0633
Brugia malayi Cytochrome P450 family protein 0.0046 0.0136 0.0179
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0029 0.0031 0.0025
Brugia malayi RNA, U transporter 1 0.0082 0.0344 0.0495
Brugia malayi Cytochrome P450 family protein 0.0029 0.0031 0.002
Echinococcus granulosus cytosolic malate dehydrogenase 0.0907 0.5235 0.5598
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0034 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0211 0.0208
Brugia malayi nuclear receptor NHR-88 0.0046 0.0132 0.0173
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0085 0.0367 0.0375
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0196 0.1021 0.1902
Echinococcus multilocularis snurportin 1 0.0306 0.1674 0.1659
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0101 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0097 0.0435 0.0633
Brugia malayi lactate dehydrogenase. 0.114 0.6612 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1444 0.8411 1
Mycobacterium ulcerans lipase LipD 0.0031 0.0043 0.0047
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0031 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0087 0.0133
Loa Loa (eye worm) glutaminase 2 0.0589 0.335 0.5053
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0501 0.0596
Schistosoma mansoni hypothetical protein 0.0796 0.4573 0.4889
Loa Loa (eye worm) hypothetical protein 0.0097 0.0435 0.0633
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0097 0.0435 0.0633
Trichomonas vaginalis helicase, putative 0.0025 0.0012 0.0014
Echinococcus multilocularis musashi 0.007 0.0276 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0097 0.0435 0.0633
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Echinococcus granulosus ecdysone induced protein 78C 0.0097 0.0435 0.0448
Onchocerca volvulus 0.0049 0.0152 0.044
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0501 0.0558
Loa Loa (eye worm) steroid hormone receptor 0.0097 0.0435 0.0633
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0501 0.0904
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0034 0.0005
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0101 0.008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1444 0.8411 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0012 0.0014
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0051 0.0164 0.0157
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0057 0.0197 0.018
Loa Loa (eye worm) CXXC zinc finger family protein 0.0112 0.0526 0.0771
Brugia malayi Calcitonin receptor-like protein seb-1 0.0179 0.0923 0.1373
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0097 0.0435 0.0633
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1444 0.8411 1
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0152 0.0144
Brugia malayi Pre-SET motif family protein 0.0398 0.2216 0.3333
Brugia malayi Pre-SET motif family protein 0.0059 0.0211 0.0293
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0046 0.0132 0.0114
Giardia lamblia Malate dehydrogenase 0.0907 0.5235 0.6224
Echinococcus granulosus muscleblind protein 0.0154 0.0775 0.0813
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0164 0.0222
Schistosoma mansoni nuclear receptor 0.0046 0.0132 0.0122
Brugia malayi Probable malate dehydrogenase, mitochondrial precursor 0.084 0.4837 0.7308
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0132 0.0173
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1444 0.8411 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0211 0.0194
Brugia malayi Importin beta-1 subunit 0.0029 0.0031 0.002
Toxoplasma gondii exonuclease III APE 0.0041 0.0101 0.0107
Echinococcus multilocularis lactate dehydrogenase a 0.114 0.6612 0.6606
Schistosoma mansoni alpha-glucosidase 0.0148 0.0739 0.0774
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0087 0.0104
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0029 0.0031 0.0025
Loa Loa (eye worm) hypothetical protein 0.0051 0.0164 0.0222
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0097 0.0435 0.0633
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0132 0.0358
Schistosoma mansoni malate dehydrogenase 0.0907 0.5235 0.5598
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0046 0.0136 0.0226
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0034 0.0061 0.0047
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0907 0.5235 0.6224
Trichomonas vaginalis esterase, putative 0.0031 0.0043 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0097 0.0435 0.0633
Brugia malayi nuclear hormone receptor 0.0046 0.0132 0.0173
Schistosoma mansoni nuclear hormone receptor 0.0097 0.0435 0.0448
Loa Loa (eye worm) hypothetical protein 0.007 0.0276 0.0392
Brugia malayi glutaminase DH11.1 0.0589 0.335 0.5053
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0034 0.004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0059 0.0211 0.0208
Trypanosoma brucei glucosidase, putative 0.0038 0.0087 0.0133
Onchocerca volvulus Protein ultraspiracle homolog 0.0097 0.0435 0.1574
Loa Loa (eye worm) nuclear hormone receptor 0.0046 0.0132 0.0173
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Loa Loa (eye worm) glutaminase 0.0589 0.335 0.5053
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0501 0.0758
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0097 0.0435 0.0633
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0501 0.0596
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.026 0.0367
Mycobacterium tuberculosis Probable esterase LipL 0.0031 0.0043 0.0022
Schistosoma mansoni malate dehydrogenase 0.114 0.6612 0.7076
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0029 0.0031 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0097 0.0435 0.0633
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0501 0.0733
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0034 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0132 0.0122
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0097 0.0435 0.0633
Brugia malayi beta-lactamase 0.0031 0.0043 0.0038
Toxoplasma gondii lactate dehydrogenase LDH2 0.114 0.6612 1
Echinococcus granulosus lamin dm0 0.007 0.0276 0.0277
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0034 0.0025
Schistosoma mansoni cpg binding protein 0.0119 0.0564 0.0586
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0029 0.0031 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0043 0.0051
Echinococcus multilocularis L lactate dehydrogenase 0.0479 0.2695 0.2682
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0043 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0097 0.0435 0.0633
Loa Loa (eye worm) hypothetical protein 0.0059 0.0211 0.0293
Brugia malayi Latrophilin receptor protein 2 0.0057 0.0197 0.0272
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0012 0.0014
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Echinococcus granulosus geminin 0.0796 0.4573 0.4889
Echinococcus granulosus lactate dehydrogenase a 0.114 0.6612 0.7076
Leishmania major malate dehydrogenase, putative 0.0661 0.3778 0.5714
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0132 0.0122
Echinococcus multilocularis dnaJ subfamily B 0.16 0.9337 0.9335
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0087 0.0104
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0101 0.012
Schistosoma mansoni coup transcription factor 0.0097 0.0435 0.0448
Loa Loa (eye worm) hypothetical protein 0.0154 0.0775 0.1149
Loa Loa (eye worm) intermediate filament protein 0.007 0.0276 0.0392
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0097 0.0435 0.0633
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0029 0.0031 0.0025
Loa Loa (eye worm) CYP4Cod1 0.0046 0.0136 0.0179
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0087 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0012 0.0014
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0501 0.0927
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Mycobacterium ulcerans glutaminase 0.0589 0.335 0.6387
Toxoplasma gondii ABC1 family protein 0.0031 0.0043 0.0018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0038
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0079 0.0066
Plasmodium vivax SET domain protein, putative 0.0059 0.0211 0.0319
Echinococcus multilocularis cpg binding protein 0.0119 0.0564 0.0547
Trichomonas vaginalis malate dehydrogenase, putative 0.0322 0.1769 0.2104
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0043 0.0051
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0907 0.5235 0.5226
Plasmodium falciparum importin beta, putative 0.0029 0.0031 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0038
Brugia malayi nuclear receptor RXR 0.0051 0.0164 0.0222
Echinococcus multilocularis lamin 0.007 0.0276 0.0259
Schistosoma mansoni hypothetical protein 0.0796 0.4573 0.4889
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0043 0.0047
Onchocerca volvulus 0.01 0.0451 0.1636
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0057 0.0197 0.0272
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0087 0.0104
Mycobacterium tuberculosis Probable lipase LipE 0.0031 0.0043 0.0022
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0087 0.0105
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0038
Loa Loa (eye worm) nuclear receptor NHR-67 0.0046 0.0132 0.0173
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0054
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0705 0.4038 0.7705
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0136 0.0179
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0029 0.0031 0.0025
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0097 0.0435 0.0448
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0012 0.0014
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0046 0.0132 0.0114
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0132 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0069 0.0269 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0012 0.0014
Brugia malayi orphan nuclear receptor NR2E1 0.0046 0.0132 0.0173
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0057 0.0197 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Mycobacterium ulcerans beta-lactamase 0.0031 0.0043 0.0047
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0031 0.0043 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0097 0.0435 0.0633
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0501 0.0927
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0034 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0085 0.0367 0.0375
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0012 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0164 0.0222
Mycobacterium tuberculosis Probable lipase LipD 0.0031 0.0043 0.0022
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0031 0.0000011646
Onchocerca volvulus 0.0112 0.0526 0.1938
Plasmodium vivax importin-beta 2, putative 0.0029 0.0031 0.0047
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0097 0.0435 0.0418
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0012 0.0014
Onchocerca volvulus Bile acid receptor homolog 0.0097 0.0435 0.1574
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0029 0.0031 0.0025
Echinococcus granulosus microtubule associated protein 2 0.1165 0.6762 0.7237
Schistosoma mansoni hypothetical protein 0.0057 0.0197 0.0192
Loa Loa (eye worm) hypothetical protein 0.0049 0.0152 0.0204
Echinococcus granulosus cpg binding protein 0.0119 0.0564 0.0586
Brugia malayi cytoplasmic intermediate filament protein 0.0038 0.0083 0.0099
Loa Loa (eye worm) cytochrome P450 0.0029 0.0031 0.002
Brugia malayi nuclear hormone receptor family member odr-7 0.0046 0.0132 0.0173
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0101 0.016
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0034 0.004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0039 0.0022
Echinococcus granulosus lactate dehydrogenase a 0.114 0.6612 0.7076
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0087 0.0105
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0097 0.0435 0.0448
Schistosoma mansoni hypothetical protein 0.0041 0.0104 0.0093
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0097 0.0435 0.0633
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0085 0.0367 0.0529
Loa Loa (eye worm) hypothetical protein 0.0057 0.0197 0.0272
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0085 0.0367 0.035
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0101 0.0089
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0211 0.0208
Echinococcus multilocularis lamin dm0 0.007 0.0276 0.0259
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0907 0.5235 0.6224
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0097 0.0435 0.0633
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0031 0.0043 0.0022
Trichomonas vaginalis glutaminase, putative 0.0589 0.335 0.3983
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0031 0.0025
Brugia malayi Glycosyl hydrolases family 31 protein 0.0172 0.0881 0.1309
Mycobacterium tuberculosis Conserved protein 0.0031 0.0043 0.0022
Loa Loa (eye worm) hypothetical protein 0.0097 0.0435 0.0633
Echinococcus granulosus survival motor neuron protein 1 0.0201 0.1053 0.1111
Leishmania major hypothetical protein, conserved 0.0031 0.0043 0.0064
Loa Loa (eye worm) hypothetical protein 0.0051 0.0164 0.0222
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0043 0.0047
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0501 0.0519
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0029 0.0031 0.0025
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0101 0.012
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0136 0.0179
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0043 0.0051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0085 0.0367 0.0375
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0097 0.0435 0.0448
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0087 0.0104
Loa Loa (eye worm) hypothetical protein 0.0051 0.0164 0.0222
Loa Loa (eye worm) hypothetical protein 0.0123 0.0587 0.0863
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0501 0.0596
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0029 0.0031 0.0025
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0501 0.0904
Echinococcus multilocularis nuclear receptor nhr 48 0.0046 0.0132 0.0114
Brugia malayi tailless protein 0.0046 0.0132 0.0173
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0012 0.0014
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0029 0.0031 0.0025
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0173
Schistosoma mansoni ap endonuclease 0.0041 0.0101 0.0089
Trichomonas vaginalis malate dehydrogenase, putative 0.0907 0.5235 0.6224
Leishmania major p450 reductase, putative 0.0026 0.0018 0.0027
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0046 0.0132 0.0122
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0029 0.0031 0.0025
Brugia malayi conserved hypotetical protein 0.0046 0.0132 0.0173
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0881 0.0865
Loa Loa (eye worm) hypothetical protein 0.114 0.6612 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0164 0.0222
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0132 0.0114
Loa Loa (eye worm) hypothetical protein 0.0097 0.0435 0.0633
Schistosoma mansoni mixed-lineage leukemia protein mll 0.024 0.1285 0.1359
Onchocerca volvulus 0.007 0.0276 0.0935
Schistosoma mansoni steroid hormone receptor ad4bp 0.0097 0.0435 0.0448
Leishmania major mitochondrial malate dehydrogenase 0.084 0.4837 0.7316
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1444 0.8411 1
Schistosoma mansoni alpha glucosidase 0.0038 0.0087 0.0075
Trichomonas vaginalis malate dehydrogenase, putative 0.0568 0.3226 0.3836
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0907 0.5235 0.6224
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0012 0.0014

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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