Detailed information for compound 162220

Basic information

Technical information
  • TDR Targets ID: 162220
  • Name: (2R)-5-(diaminomethylideneamino)-2-[5-(6-oxo- 3H-purin-9-yl)pentoxycarbonylamino]pentanoic acid
  • MW: 422.439 | Formula: C17H26N8O5
  • H donors: 5 H acceptors: 7 LogP: -0.07 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=N)NCCC[C@H](C(=O)O)NC(=O)OCCCCCn1cnc2c1ncnc2O
  • InChi: 1S/C17H26N8O5/c18-16(19)20-6-4-5-11(15(27)28)24-17(29)30-8-3-1-2-7-25-10-23-12-13(25)21-9-22-14(12)26/h9-11H,1-8H2,(H,24,29)(H,27,28)(H4,18,19,20)(H,21,22,26)/t11-/m1/s1
  • InChiKey: UXOOSQUBNBVHPO-LLVKDONJSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R)-5-guanidino-2-[5-(6-oxo-3H-purin-9-yl)pentoxycarbonylamino]pentanoic acid
  • (2R)-5-guanidino-2-[[oxo-[5-(6-oxo-3H-purin-9-yl)pentoxy]methyl]amino]pentanoic acid
  • (2R)-5-[bis(azanyl)methylideneamino]-2-[5-(6-oxo-3H-purin-9-yl)pentoxycarbonylamino]pentanoic acid
  • (2R)-5-guanidino-2-[5-(6-keto-3H-purin-9-yl)pentoxycarbonylamino]valeric acid
  • PCF 39

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei telomerase reverse transcriptase 0.0999 0.2716 1
Echinococcus multilocularis muscleblind protein 0.0165 0.0431 0.1576
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0051 0.2692
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0124 0.2979
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0008 0.0002 0.0006
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0139 0.0508
Loa Loa (eye worm) hypothetical protein 0.0076 0.0188 0.1791
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.001 0.0229
Schistosoma mansoni glutaminase 0.0159 0.0416 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0091
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0008 0.0002 0.0006
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0028 0.0102
Brugia malayi ecdysteroid receptor 0.0011 0.001 0.0013
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0008 0.0002 0.0042
Schistosoma mansoni hypothetical protein 0.0008 0.0002 0.0042
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.0188 0.143
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0266
Trypanosoma brucei Heat shock protein 83, putative 0.0018 0.0028 0.0103
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.001 0.0035
Mycobacterium leprae Probable lipase LipE 0.0076 0.0188 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0014
Brugia malayi beta-lactamase family protein 0.0076 0.0188 0.0259
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0028 0.0103
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0033 0.012
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0139 0.334
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0028 0.0102
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0009 0.0003 0.0031
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.001 0.0229
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0028 0.0038
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.0134 0.1273
Schistosoma mansoni hypothetical protein 0.0045 0.0102 0.2458
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.001 0.0091
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0008 0.0002 0.0006
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.0277 0.1012
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0139 0.0511
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.031
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0028 0.0103
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi follicle stimulating hormone receptor 0.0246 0.0651 0.0897
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0188 0.4528
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0033 0.0783
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Trypanosoma cruzi heat shock protein 90, putative 0.0014 0.0018 0.0066
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0008 0.0002 0.0042
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0008 0.0002 0.0006
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0124 0.0456
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0008 0.0002 0.0006
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0107 0.039
Schistosoma mansoni hypothetical protein 0.0008 0.0002 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Giardia lamblia Heat shock protein HSP 90-alpha 0.0014 0.0018 0.006
Loa Loa (eye worm) hypothetical protein 0.0009 0.0003 0.0031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0188 0.4528
Echinococcus granulosus Niemann Pick C1 protein 0.0155 0.0405 0.148
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.1016
Loa Loa (eye worm) hypothetical protein 0.0071 0.0175 0.1662
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0017
Onchocerca volvulus 0.0008 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.001 0.0091
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0188 0.4528
Mycobacterium ulcerans hypothetical protein 0.0076 0.0188 0.4528
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.0188 0.4528
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.001 0.001
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0051 0.007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0028 0.0102
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.0188 0.0259
Mycobacterium tuberculosis Conserved protein 0.0076 0.0188 0.143
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Schistosoma mansoni hypothetical protein 0.0099 0.025 0.6006
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0028 0.0102
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.001 0.0035
Trypanosoma brucei heat shock protein, putative 0.0018 0.0028 0.0103
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0008 0.0002 0.0006
Trypanosoma cruzi heat shock protein 85, putative 0.0018 0.0028 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0109 0.0277 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0139 0.0508
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.001 0.0229
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0051 0.183
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0008 0.0002 0.0006
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.001 0.0035
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0018 0.0028 0.0104
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0124 0.0453
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni survival motor neuron protein 0.008 0.0198 0.4754
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0008 0.0002 0.0006
Brugia malayi CHE-14 protein 0.0047 0.0107 0.0147
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi nuclear receptor NHR-88 0.0011 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0008 0.0002 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0008 0.0002 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trypanosoma brucei protein kinase, putative 0.0053 0.0124 0.0456
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0124 0.2979
Brugia malayi SEA domain containing protein 0.0008 0.0002 0.0002
Trichomonas vaginalis ubiquitin specific protease, putative 0.0008 0.0002 0.0042
Schistosoma mansoni hypothetical protein 0.0045 0.0102 0.2458
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0188 0.0693
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0017
Schistosoma mansoni hypothetical protein 0.0045 0.0102 0.2458
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0027 0.0053 0.1276
Loa Loa (eye worm) glutaminase 0.0159 0.0416 0.3955
Leishmania major telomerase reverse transcriptase, putative 0.0999 0.2716 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0053 0.0195
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0008 0.0002 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0008 0.0002 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.001 0.0035
Onchocerca volvulus 0.0008 0.0002 0.0002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0008 0.0002 0.0063
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Toxoplasma gondii heat shock protein HSP90 0.0018 0.0028 0.0103
Brugia malayi Muscleblind-like protein 0.0165 0.0431 0.0593
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0008 0.0002 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0008 0.0002 0.0006
Trypanosoma brucei heat shock protein, putative 0.0018 0.0028 0.0103
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.001 0.0229
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0124 0.0456
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus granulosus endoplasmin 0.0014 0.0018 0.0066
Brugia malayi heat shock protein 90 0.0018 0.0028 0.0038
Trypanosoma brucei heat shock protein, putative 0.0018 0.0028 0.0103
Echinococcus granulosus ubiquitin specific protease 41 0.0027 0.0053 0.0194
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Loa Loa (eye worm) hypothetical protein 0.0076 0.0188 0.1791
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0124 0.0456
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.001 0.0013
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.0188 0.1791
Echinococcus multilocularis endoplasmin 0.0014 0.0018 0.0066
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0008 0.0002 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis rotamase, putative 0.0018 0.0028 0.0677
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0008 0.0002 0.0006
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0124 0.0456
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0008 0.0002 0.0006
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0051 0.0385
Onchocerca volvulus 0.0008 0.0002 0.0002
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0027 0.0053 0.1916
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0051 0.1219
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.001 0.001
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0008 0.0002 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0051 0.0187
Onchocerca volvulus 0.0026 0.0051 0.0051
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) DOMON domain-containing protein 0.0008 0.0002 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.001 0.0035
Schistosoma mansoni endoplasmin 0.0018 0.0028 0.0673
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.001 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.001 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0051 0.183
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0014 0.0018 0.0066
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.031
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Echinococcus multilocularis GPCR, family 2 0.0018 0.0028 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Brugia malayi isocitrate dehydrogenase 0.0018 0.0028 0.0039
Loa Loa (eye worm) hypothetical protein 0.0026 0.0051 0.0482
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0029 0.0705
Brugia malayi Niemann-Pick C1 protein precursor 0.0109 0.0277 0.0381
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0014 0.0018 0.0955
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0017
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.001 0.0229
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0008 0.0002 0.0006
Schistosoma mansoni heat shock protein 0.0018 0.0028 0.0673
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0124 0.2979
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Brugia malayi Endoplasmin precursor 0.0018 0.0028 0.0038
Echinococcus multilocularis protein patched 0.0047 0.0107 0.039
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0028 0.0039
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0139 0.334
Echinococcus granulosus geminin 0.0099 0.025 0.0913
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Toxoplasma gondii hypothetical protein 0.0008 0.0002 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0008 0.0002 0.0006
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.0188 0.143
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.001 0.0013
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.0188 0.143
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Onchocerca volvulus 0.0008 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0027 0.0053 0.1276
Brugia malayi MAP kinase sur-1 0.0053 0.0124 0.017
Echinococcus multilocularis transcription factor eb 0.0122 0.0314 0.1149
Trichomonas vaginalis ubiquitin specific protease, putative 0.0008 0.0002 0.0042
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0128 0.1218
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0008 0.0002 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis heat shock protein 0.0018 0.0028 0.0102
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0008 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Brugia malayi hypothetical protein 0.0008 0.0002 0.0002
Plasmodium falciparum ubiquitin specific protease, putative 0.0008 0.0002 0.0006
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0124 0.0456
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.003 0.0225
Onchocerca volvulus 0.0009 0.0003 0.0003
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Echinococcus multilocularis heat shock protein 90 0.0014 0.0018 0.0066
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0008 0.0002 0.0006
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.003 0.0225
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0091
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0028 0.0103
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0027 0.0053 0.0194
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.031
Echinococcus multilocularis ubiquitin specific protease 41 0.0027 0.0053 0.0194
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Giardia lamblia Telomerase catalytic subunit 0.0999 0.2716 1
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.0188 0.143
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0124 0.0453
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0076 0.0188 0.1791
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0014 0.0018 0.0066
Schistosoma mansoni thyroid hormone receptor 0.0011 0.001 0.0229
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.001 0.0091
Entamoeba histolytica heat shock protein 90, putative 0.0018 0.0028 0.101
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.001 0.0229
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0188 0.4528
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.0188 0.0688
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.001 0.0013
Onchocerca volvulus 0.0008 0.0002 0.0002
Echinococcus granulosus heat shock protein 90 0.0014 0.0018 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi steroid hormone receptor 0.0011 0.001 0.0013
Trypanosoma brucei heat shock protein, putative 0.0018 0.0028 0.0103
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0018 0.0028 0.0104
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0008 0.0002 0.0042
Onchocerca volvulus 0.0009 0.0003 0.0003
Toxoplasma gondii ABC1 family protein 0.0076 0.0188 0.0693
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0188 0.4528
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0028 0.0102
Onchocerca volvulus Huntingtin homolog 0.0071 0.0175 0.0175
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0139 0.334
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0188 0.0693
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0028 0.0103
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0028 0.0102
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0999 0.2716 1
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0008 0.0002 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0008 0.0002 0.0006
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.001 0.0013
Toxoplasma gondii RNA-directed DNA polymerase 0.0999 0.2716 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0091
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0008 0.0002 0.0042
Trypanosoma brucei heat shock protein, putative 0.0018 0.0028 0.0103
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0008 0.0002 0.0006
Trichomonas vaginalis esterase, putative 0.0076 0.0188 0.4528
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus granulosus neuropeptide s receptor 0.1006 0.2734 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0033 0.5
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0124 0.0453
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0018 0.0029 0.0279
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.0134 0.0184
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Plasmodium falciparum heat shock protein 90 0.0018 0.0028 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0124 0.0456
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0122 0.0312 0.2974
Schistosoma mansoni hypothetical protein 0.0018 0.0028 0.0672
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0014 0.0018 0.5
Brugia malayi beta-lactamase 0.0076 0.0188 0.0259
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0051 0.007
Trypanosoma cruzi heat shock protein 90, putative 0.0011 0.0008 0.0029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0107 0.2569
Trypanosoma cruzi heat shock protein 85, putative 0.0014 0.0018 0.0066
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.001 0.0013
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0028 0.0103
Trypanosoma cruzi heat shock protein 85, putative 0.0018 0.0028 0.0103
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0027 0.0053 0.0194
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Mycobacterium ulcerans hypothetical protein 0.0026 0.0051 0.1219
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Onchocerca volvulus Huntingtin homolog 0.0071 0.0175 0.0175
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0008 0.0002 0.0006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0246 0.0651 0.62
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0027 0.0053 0.0195
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0053 0.0195
Brugia malayi Muscle positioning protein 4 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0003 0.0031
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.001 0.0035
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0017
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0051 0.1219
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0085 0.0117
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0091
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0999 0.2716 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0051 0.1219
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.001 0.0035
Mycobacterium tuberculosis Conserved protein 0.0076 0.0188 0.143
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.0277 0.1012
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0188 0.0693
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis heat shock protein, putative 0.0011 0.0009 0.0217
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Toxoplasma gondii ubiquitin-specific protease USP4 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0008 0.0002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0165 0.0431 0.41
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0107 0.1016
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0488 0.1316 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.001 0.0091
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0124 0.045
Treponema pallidum heat shock protein 90 0.0014 0.0018 0.5
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.001 0.0035
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0027 0.0053 0.0189
Plasmodium vivax endoplasmin, putative 0.0018 0.0028 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Schistosoma mansoni hypothetical protein 0.0018 0.0028 0.0672
Schistosoma mansoni thyroid hormone receptor 0.0011 0.001 0.0229
Schistosoma mansoni calpain-7 (C02 family) 0.0008 0.0002 0.0042
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0008 0.0002 0.0006
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0028 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0027 0.0053 0.1276
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.0188 0.143
Mycobacterium ulcerans lipase LipD 0.0076 0.0188 0.4528
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Echinococcus granulosus FTZ F1 alpha 0.0011 0.001 0.0035
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0122 0.0314 0.0432
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0008 0.0002 0.0042
Brugia malayi glutaminase DH11.1 0.0159 0.0416 0.0572
Giardia lamblia Grp94/Hsp90 0.0014 0.0018 0.006
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0091
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0028 0.0102
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.001 0.0035
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0091
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis endoplasmin, putative 0.0011 0.0009 0.0217
Onchocerca volvulus 0.0076 0.0188 0.0188
Giardia lamblia Heat shock protein HSP 90-alpha 0.0018 0.0028 0.0097
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0008 0.0002 0.0006
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0051 0.1219
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Echinococcus multilocularis protein dispatched 1 0.0053 0.0125 0.0456
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0051 0.1219
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0028 0.0102
Schistosoma mansoni hypothetical protein 0.0009 0.0003 0.0077
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0008 0.0002 0.0006
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0002 0.0006
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Echinococcus multilocularis expressed conserved protein 0.0102 0.0259 0.0946
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0124 0.2979
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0017
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0008 0.0002 0.0006
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.0188 0.143
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Echinococcus multilocularis neuropeptide s receptor 0.1006 0.2734 1
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0188 0.0693
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0014 0.0018 0.0137
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Echinococcus granulosus MAM 0.0009 0.0003 0.0012
Trichomonas vaginalis ubiquitin specific protease, putative 0.0008 0.0002 0.0042
Echinococcus granulosus neuropeptide receptor A26 0.1006 0.2734 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0175 0.1662
Brugia malayi ubiquitin specific protease 14 0.0008 0.0002 0.0002
Echinococcus granulosus transcription factor eb 0.0122 0.0314 0.1149
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0008 0.0002 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.003 0.0225
Schistosoma mansoni peptidase 0.0009 0.0003 0.0074
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0008 0.0002 0.0042
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0057 0.0135 0.1289
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Brugia malayi Protein kinase domain containing protein 0.0009 0.0003 0.0004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0063
Echinococcus multilocularis survival motor neuron protein 1 0.0391 0.1051 0.3844
Brugia malayi hypothetical protein 0.0071 0.0175 0.024
Loa Loa (eye worm) hypothetical protein 0.0109 0.0277 0.2634
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.001 0.0229
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.001 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Plasmodium vivax telomerase reverse transcriptase, putative 0.0999 0.2716 1
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0107 0.039
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0051 0.1219
Schistosoma mansoni hypothetical protein 0.008 0.0198 0.4754
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.001 0.0035
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0008 0.0002 0.0042
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0008 0.0002 0.0042
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0051 0.0187
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0027 0.0053 0.1276
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0807
Loa Loa (eye worm) hypothetical protein 0.0057 0.0134 0.1273
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0091
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0018 0.0028 0.0104
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0028 0.0674
Plasmodium falciparum telomerase reverse transcriptase 0.0999 0.2716 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0008 0.0002 0.0063
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0008 0.0002 0.0006
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0033 0.0247
Schistosoma mansoni niemann-pick C1 (NPC1) 0.011 0.0281 0.677
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0053 0.1276
Schistosoma mansoni rotamase 0.0018 0.0029 0.0705
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.001 0.0013
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0028 0.0103
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0008 0.0002 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) heat shock protein 90 0.0018 0.0028 0.0266
Onchocerca volvulus 0.0008 0.0002 0.0002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0124 0.0456
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.001 0.0035
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0028 0.0102
Echinococcus multilocularis neuropeptide receptor A26 0.1006 0.2734 1
Entamoeba histolytica hypothetical protein 0.0008 0.0002 0.0063
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0028 0.0038
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0124 0.0453
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0051 0.1219
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0008 0.0002 0.0006
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0008 0.0002 0.0042
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.001 0.0091
Onchocerca volvulus 0.0008 0.0002 0.0002
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.001 0.0013
Onchocerca volvulus 0.0011 0.001 0.001
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0008 0.0002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0014
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Schistosoma mansoni hypothetical protein 0.0009 0.0003 0.0077
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.0134 0.0184
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0027 0.0053 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.001 0.0013
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0008 0.0002 0.0006
Trypanosoma cruzi heat shock protein 90, putative 0.0018 0.0028 0.0103
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Plasmodium vivax heat shock protein 86, putative 0.0018 0.0028 0.0103
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0122 0.0312 0.2974
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Echinococcus granulosus GPCR family 2 0.0018 0.0028 0.0102
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0018 0.0029 0.004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0008 0.0002 0.0042
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0008 0.0002 0.0006
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0051 0.0187
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0008 0.0002 0.0042
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0139 0.0191
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0188 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0188 0.1791
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0018 0.0028 0.1016
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.001 0.0035
Entamoeba histolytica heat shock protein 90, putative 0.0018 0.0028 0.101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis rotamase, putative 0.0018 0.0029 0.0705
Loa Loa (eye worm) glutaminase 2 0.0159 0.0416 0.3955
Plasmodium falciparum ubiquitin specific protease, putative 0.0008 0.0002 0.0006
Trypanosoma cruzi heat shock protein 85, putative 0.0018 0.0028 0.0103
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Brugia malayi Telomerase reverse transcriptase 0.2659 0.7263 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0017
Brugia malayi hypothetical protein 0.0391 0.1051 0.1447
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0008 0.0002 0.0006
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0053 0.0195
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0008 0.0002 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0124 0.2979
Loa Loa (eye worm) TK/ALK protein kinase 0.0009 0.0003 0.0031
Echinococcus granulosus survival motor neuron protein 1 0.0391 0.1051 0.3844
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0051 0.183
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Echinococcus multilocularis MAM 0.0009 0.0003 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.001 0.0013
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0018 0.0433
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni calpain-7 (C02 family) 0.0008 0.0002 0.0042
Schistosoma mansoni hypothetical protein 0.0099 0.025 0.6006
Brugia malayi nuclear hormone receptor 0.0011 0.001 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.001 0.0013
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.001 0.0229
Loa Loa (eye worm) beta-lactamase 0.0076 0.0188 0.1791
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0033 0.012
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.0188 0.4528
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0018 0.0433
Schistosoma mansoni heat shock protein 0.0018 0.0028 0.0673
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0091
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0008 0.0002 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Mycobacterium ulcerans glutaminase 0.0159 0.0416 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0027 0.0053 0.0194
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0107 0.039
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.001 0.0013
Echinococcus granulosus ubiquitin specific peptidase c family 0.0008 0.0002 0.0006
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0026 0.0051 0.0482
Onchocerca volvulus 0.0008 0.0002 0.0002
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0027 0.0053 0.0194
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0028 0.0266
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.008 0.0198 0.0272
Toxoplasma gondii peptidylprolyl isomerase 0.0018 0.0028 0.0104
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Plasmodium vivax ubiquitin specific protease, putative 0.0008 0.0002 0.0006
Trypanosoma brucei heat shock protein, putative 0.0018 0.0028 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0008 0.0002 0.0042
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0051 0.0482
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.001 0.0091
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0051 0.0385
Schistosoma mansoni hypothetical protein 0.0039 0.0085 0.204
Trypanosoma brucei heat shock protein 90, putative 0.0018 0.0028 0.0103
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Loa Loa (eye worm) hypothetical protein 0.0076 0.0188 0.1791
Schistosoma mansoni hypothetical protein 0.0018 0.0028 0.0672
Loa Loa (eye worm) hypothetical protein 0.0165 0.0431 0.41
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0076 0.0188 0.1791
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Trypanosoma brucei heat shock protein, putative 0.0018 0.0028 0.0103
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0124 0.1178
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Plasmodium falciparum endoplasmin, putative 0.0011 0.0009 0.0033
Echinococcus multilocularis expressed protein 0.0018 0.0029 0.0107
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Trichomonas vaginalis glutaminase, putative 0.0159 0.0416 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0155 0.0405 0.148
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0008 0.0002 0.0042
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0124 0.0456
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis heat shock protein, putative 0.0018 0.0028 0.0673
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Loa Loa (eye worm) endoplasmin 0.0018 0.0028 0.0266
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0008 0.0002 0.0006
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0008 0.0002 0.0017
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0008 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0391 0.1051 1
Schistosoma mansoni coup transcription factor 0.0011 0.001 0.0229
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0008 0.0002 0.0006
Mycobacterium ulcerans heat shock protein 90 0.0014 0.0018 0.0433
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.001 0.0035
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0188 0.4528
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.001 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Echinococcus granulosus expressed protein 0.0018 0.0029 0.0107
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0008 0.0002 0.0006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0028 0.0102
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0008 0.0002 0.0006
Onchocerca volvulus 0.008 0.0198 0.0198
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0139 0.1055
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0028 0.0213
Mycobacterium tuberculosis Conserved protein 0.0076 0.0188 0.143
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trypanosoma cruzi Heat shock protein 83, putative 0.0018 0.0028 0.0103
Trypanosoma brucei heat shock protein 90, putative 0.0018 0.0028 0.0103
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0008 0.0002 0.0042
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0051 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trypanosoma brucei heat shock protein, putative 0.0018 0.0028 0.0103
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.001 0.0091
Schistosoma mansoni patched 1 0.0047 0.0107 0.2569
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0017
Onchocerca volvulus 0.0076 0.0188 0.0188
Echinococcus multilocularis geminin 0.0099 0.025 0.0913
Schistosoma mansoni hypothetical protein 0.0045 0.0102 0.2458
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Onchocerca volvulus 0.0012 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.031
Echinococcus granulosus expressed conserved protein 0.0102 0.0259 0.0946
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0473 0.1274 0.466
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0018 0.0028 0.0104
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0188 0.4528
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0018 0.0433
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.0188 0.0688
Echinococcus multilocularis heat shock protein 90 0.0018 0.0028 0.0102
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Toxoplasma gondii heat shock protein 90, putative 0.0018 0.0028 0.0103
Echinococcus granulosus muscleblind protein 0.0165 0.0431 0.1576
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0028 0.0266
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0051 0.2692
Brugia malayi hypothetical protein 0.0009 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0018 0.0028 0.0672
Brugia malayi beta-lactamase family protein 0.0076 0.0188 0.0259
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0042
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Loa Loa (eye worm) hypothetical protein 0.0027 0.0053 0.0505
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0008 0.0002 0.0006
Mycobacterium ulcerans beta-lactamase 0.0076 0.0188 0.4528
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Echinococcus multilocularis muscleblind protein 1 0.0165 0.0431 0.1576
Schistosoma mansoni nuclear hormone receptor 0.0011 0.001 0.0229
Schistosoma mansoni endoplasmin 0.0018 0.0028 0.0673
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.001 0.001
Onchocerca volvulus 0.0076 0.0188 0.0188
Echinococcus granulosus heat shock protein 90 0.0018 0.0028 0.0102
Leishmania major heat shock protein 83-1 0.0018 0.0028 0.0103
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.0188 0.143
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0008 0.0002 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.001 0.0091
Echinococcus multilocularis expressed protein 0.0008 0.0002 0.0006
Leishmania major hypothetical protein, conserved 0.0076 0.0188 0.0693
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.003 0.0225
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0008 0.0002 0.0063
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0008 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0028 0.0103
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.001 0.0035
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.001 0.0013
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0008 0.0002 0.0002
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0028 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0008 0.0002 0.0042
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.001 0.0229
Echinococcus granulosus heat shock protein 0.0018 0.0028 0.0102

Activities

Activity type Activity value Assay description Source Reference
CTL activity (functional) 0 M In vitro cytotoxic T-Lymphocyte (CTL) activity of the compound relative to interleukin 2 was obtained at a concentration of 10 e -7 M(++ represents 41 - 60% of interleukin 2) ChEMBL. 9288170

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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