Detailed information for compound 1693270

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 478.394 | Formula: C24H29BrFNO3
  • H donors: 1 H acceptors: 2 LogP: 5.19 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: FCC[N+]1(C)[C@@H]2CC[C@H]1C[C@H](C2)OC(=O)C(c1ccccc1)(c1ccccc1)O.[Br-]
  • InChi: 1S/C24H29FNO3.BrH/c1-26(15-14-25)20-12-13-21(26)17-22(16-20)29-23(27)24(28,18-8-4-2-5-9-18)19-10-6-3-7-11-19;/h2-11,20-22,28H,12-17H2,1H3;1H/q+1;/p-1/t20-,21+,22+,26?;
  • InChiKey: FNUZASGZEHGWQM-XDKPLUGXSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0068 0.0326 0.0859
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0274 0.0798
Echinococcus granulosus caspase 2 0.0059 0.0274 0.0491
Echinococcus granulosus sentrin specific protease 1 0.0014 0.0018 0.001
Schistosoma mansoni lozenge 0.006 0.0283 0.0381
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0059 0.0274 0.2643
Echinococcus granulosus sentrin specific protease 7 0.0014 0.0018 0.001
Schistosoma mansoni phosphoglycerate kinase 0.0185 0.1002 0.1391
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0012
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0044 0.019 0.18
Schistosoma mansoni caspase-7 (C14 family) 0.0059 0.0274 0.0369
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0012 0.0035
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0177 0.031
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0067 0.032 0.0577
Echinococcus multilocularis carbonic anhydrase 0.0117 0.0612 0.1125
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0185 0.1002 0.0985
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0557 0.3149 0.9171
Giardia lamblia Sentrin specific protease, putative 0.0014 0.0018 0.0055
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0026 0.007
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0698 0.0965
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0074 0.0363 0.3622
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0143 0.0377
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.075 0.1039
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0059 0.0155
Loa Loa (eye worm) hypothetical protein 0.0034 0.0129 0.0222
Trypanosoma brucei DNA polymerase IV, putative 0.014 0.0743 0.1957
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0132 0.0698 0.1289
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0198 0.0578
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0557 0.3149 0.3137
Schistosoma mansoni ap endonuclease 0.002 0.0052 0.0058
Plasmodium vivax SET domain protein, putative 0.0067 0.032 0.3107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0029
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0311 0.0422
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.013 0.0683 0.1869
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0052 0.0034
Loa Loa (eye worm) hypothetical protein 0.0089 0.0446 0.0816
Plasmodium vivax phosphoglycerate kinase, putative 0.0185 0.1002 1
Trypanosoma cruzi metacaspase, putative 0.0059 0.0274 0.0721
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0117 0.0612 0.1125
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0468 0.1363
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0068 0.0327 0.0591
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0046 0.0201 0.201
Loa Loa (eye worm) twinkle helicase 0.0112 0.058 0.1067
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0018 0.0175
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0026 0.0027
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.0348 0.0632
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0106 0.0948
Loa Loa (eye worm) hypothetical protein 0.0073 0.0356 0.0646
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0274 0.0798
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0052 0.0152
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0468 0.0854
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0047 0.0208 0.0368
Echinococcus granulosus zinc finger protein 0.0041 0.0173 0.0303
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0029
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0143 0.0185
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0292 0.0395
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0468 0.4668
Schistosoma mansoni hypothetical protein 0.0034 0.0129 0.0166
Trypanosoma brucei metacaspase 0.0059 0.0274 0.0721
Trypanosoma brucei phosphoglycerate kinase, putative 0.0068 0.0326 0.0859
Brugia malayi MH2 domain containing protein 0.0117 0.0608 0.1118
Schistosoma mansoni zinc finger protein 0.0041 0.0173 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0468 0.0641
Trypanosoma brucei unspecified product 0.014 0.0743 0.1957
Entamoeba histolytica hypothetical protein 0.0035 0.0137 0.1372
Echinococcus granulosus carbonic anhydrase 0.0117 0.0612 0.1125
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0129 0.022
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0421 0.0766
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Trypanosoma brucei metacaspase 5, putative 0.0059 0.0274 0.0721
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0317 0.1762 0.4642
Loa Loa (eye worm) hypothetical protein 0.0481 0.2712 0.5066
Leishmania major carbonic anhydrase-like protein 0.0217 0.1186 0.3102
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0185 0.1002 0.4431
Brugia malayi hypothetical protein 0.0481 0.2712 0.5065
Toxoplasma gondii exonuclease III APE 0.002 0.0052 0.0406
Trypanosoma brucei phosphoglycerate kinase 0.0185 0.1002 0.2639
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0096 0.0487 0.0669
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Echinococcus multilocularis SAM and MBT domain containing protein 0.0204 0.1114 0.2067
Echinococcus granulosus GPCR family 2 0.0034 0.0129 0.022
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.0348 0.0474
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0074 0.0363 0.1058
Echinococcus granulosus sentrin specific protease 8 0.0074 0.0363 0.0658
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0477 0.1257
Plasmodium vivax metacaspase 1, putative 0.0059 0.0274 0.2643
Trypanosoma cruzi metacaspase 5, putative 0.0059 0.0274 0.0721
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0068 0.0326 0.0859
Entamoeba histolytica hypothetical protein 0.0035 0.0137 0.1372
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0317 0.1762 0.4642
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0468 0.0854
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0052 0.0406
Loa Loa (eye worm) hypothetical protein 0.0144 0.0765 0.1414
Loa Loa (eye worm) hypothetical protein 0.0088 0.0444 0.0813
Schistosoma mansoni hypothetical protein 0.0313 0.1742 0.2431
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0343 0.0621
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0392 0.2195 1
Brugia malayi hypothetical protein 0.0035 0.0137 0.0235
Trypanosoma cruzi DNA polymerase eta, putative 0.0152 0.0813 0.2141
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0072 0.0209
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0012 0.0035
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0135 0.0173
Trypanosoma brucei Metacaspase-4 0.0059 0.0274 0.0721
Echinococcus multilocularis kelch ECH associated protein 1 0.0092 0.0467 0.0854
Plasmodium vivax sentrin-specific protease 1, putative 0.0014 0.0018 0.0055
Echinococcus multilocularis caspase 8 0.0059 0.0274 0.0491
Echinococcus multilocularis carbonic anhydrase II 0.0217 0.1186 0.2202
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.0551 0.1012
Trypanosoma cruzi DNA polymerase eta, putative 0.0086 0.0432 0.1137
Echinococcus multilocularis sentrin specific protease 7 0.0014 0.0018 0.001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0143 0.0377
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0026 0.0029
Schistosoma mansoni DNA polymerase eta 0.0152 0.0813 0.1126
Schistosoma mansoni ets-related 0.0215 0.1175 0.1635
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0018 0.001
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0106 0.0279
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.075 0.1385
Giardia lamblia Kinase, PLK 0.0092 0.0468 0.4602
Loa Loa (eye worm) glutaminase 2 0.0606 0.3429 0.6413
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0421 0.0766
Echinococcus granulosus kelch ECH associated protein 1 like 0.0092 0.0467 0.0854
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0052 0.0406
Loa Loa (eye worm) hypothetical protein 0.0036 0.0143 0.0247
Schistosoma mansoni myelin transcription factor 1 myt1 0.0233 0.1277 0.1779
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0143 0.0246
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0669 0.3796 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0468 0.1363
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0115 0.0596 0.157
Entamoeba histolytica hypothetical protein 0.0035 0.0137 0.1372
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0026 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0052 0.0138
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0096 0.016
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0026 0.0021
Echinococcus granulosus carbonic anhydrase 0.0117 0.0612 0.1125
Chlamydia trachomatis phosphoglycerate kinase 0.0185 0.1002 0.452
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0014 0.0018 0.0055
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0274 0.0798
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0343 0.0623
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0123 0.0645 0.1187
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.075 0.1385
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0311 0.0561
Echinococcus multilocularis kelch ECH associated protein 1 0.0092 0.0467 0.0854
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0059 0.0473
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.0348 0.0888
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0026 0.0144
Mycobacterium ulcerans lipoprotein LpqF 0.0062 0.0294 0.0715
Brugia malayi Pre-SET motif family protein 0.0462 0.2599 0.4854
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0143 0.0246
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0062 0.0294 0.0276
Trypanosoma brucei unspecified product 0.0066 0.0316 0.0831
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0026 0.007
Echinococcus granulosus endonuclease exonuclease phosphatase 0.081 0.4607 0.8621
Echinococcus granulosus caspase 0.0059 0.0274 0.0491
Entamoeba histolytica hypothetical protein 0.0024 0.0071 0.071
Echinococcus multilocularis zinc finger protein 0.0041 0.0173 0.0303
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0104 0.0172
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0052 0.0077
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0348 0.0918
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.028 0.0502
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0096 0.0487 0.0891
Echinococcus multilocularis caspase 2 0.0059 0.0274 0.0491
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0058 0.0086
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.075 0.1039
Loa Loa (eye worm) hypothetical protein 0.0083 0.0413 0.0753
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0018 0.001
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0143 0.0246
Trypanosoma brucei DNA polymerase eta, putative 0.0152 0.0813 0.2141
Leishmania major DNA polymerase kappa, putative 0.003 0.0106 0.0248
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0026 0.0027
Brugia malayi Importin beta-1 subunit 0.0029 0.0104 0.0172
Loa Loa (eye worm) hypothetical protein 0.0233 0.1277 0.2375
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.081 0.4607 0.8621
Brugia malayi Pre-SET motif family protein 0.0067 0.032 0.0577
Schistosoma mansoni hypothetical protein 0.0042 0.0177 0.0232
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0129 0.022
Plasmodium falciparum metacaspase 1 0.0059 0.0274 0.2643
Leishmania major phosphoglycerate kinase C, glycosomal 0.0185 0.1002 0.2615
Schistosoma mansoni carbonic anhydrase-related 0.0117 0.0612 0.0844
Schistosoma mansoni cpg binding protein 0.0034 0.0128 0.0164
Entamoeba histolytica hypothetical protein 0.0035 0.0137 0.1372
Schistosoma mansoni hypothetical protein 0.0035 0.0137 0.0177
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0059 0.0274 0.0491
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0067 0.032 0.0433
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0174 0.0304
Loa Loa (eye worm) hypothetical protein 0.0185 0.1002 0.1858
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0071 0.0156
Schistosoma mansoni hypothetical protein 0.0034 0.0129 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0106 0.0279
Schistosoma mansoni cpg binding protein 0.0034 0.0128 0.0164
Trichomonas vaginalis ran, putative 0.0022 0.0059 0.0172
Leishmania major GTP-binding protein, putative 0.0022 0.0059 0.0124
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.052 0.0714
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.028 0.0502
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0068 0.0326 0.083
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0026 0.0021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0274 0.0798
Schistosoma mansoni sex comb on midleg homolog 0.0204 0.1114 0.1549
Leishmania major DNA polymerase eta, putative 0.0086 0.0432 0.1109
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.04 0.1054
Loa Loa (eye worm) hypothetical protein 0.0481 0.2712 0.5066
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0392 0.2195 0.6898
Schistosoma mansoni terminal deoxycytidyl transferase 0.0096 0.0487 0.0669
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0348 0.0918
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0018 0.0051
Brugia malayi RNA, U transporter 1 0.0083 0.0416 0.0757
Loa Loa (eye worm) hypothetical protein 0.0937 0.5341 1
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0608 0.112
Onchocerca volvulus 0.0526 0.2966 0.8439
Echinococcus multilocularis histone acetyltransferase MYST2 0.0233 0.1277 0.2374
Schistosoma mansoni phosphoglycerate kinase 0.0185 0.1002 0.1391
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0059 0.0274 0.0492
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0317 0.1762 0.4624
Echinococcus granulosus snurportin 1 0.0313 0.1742 0.3245
Echinococcus multilocularis carbonic anhydrase 0.0117 0.0612 0.1125
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0348 0.0918
Mycobacterium ulcerans hypothetical protein 0.003 0.0106 0.0159
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0014 0.0018 0.0009
Brugia malayi Phosphoglycerate kinase 0.0185 0.1002 0.1856
Mycobacterium ulcerans DNA polymerase IV 0.0155 0.0827 0.2294
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0143 0.0377
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0072 0.0189
Echinococcus multilocularis tar DNA binding protein 0.0132 0.0698 0.1288
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0233 0.1277 0.2374
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0106 0.0279
Schistosoma mansoni ap endonuclease 0.002 0.0052 0.0058
Giardia lamblia DNA damage repair protein 0.003 0.0106 0.0948
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0074 0.0363 0.0658
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0217 0.1186 0.3124
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0117 0.0612 0.1125
Schistosoma mansoni carbonic anhydrase 0.0117 0.0612 0.0844
Trypanosoma brucei SUMO1/Ulp2, putative 0.0014 0.0018 0.0046
Echinococcus multilocularis muscleblind protein 1 0.0937 0.5341 1
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0062 0.0294 0.0724
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0068 0.0326 0.0859
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0059 0.0473
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0059 0.0088
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0096 0.0487 0.0891
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0204 0.1114 0.3138
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0071 0.0596
Schistosoma mansoni tsg101-related 0.0057 0.0261 0.0351
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0072 0.0209
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0074 0.0363 0.1058
Brugia malayi RNA binding protein 0.0132 0.0698 0.1288
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0018 0.0051
Brugia malayi jmjC domain containing protein 0.0016 0.0026 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0012 0.0032
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0185 0.1002 1
Schistosoma mansoni bromodomain containing protein 0.013 0.0687 0.0949
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0143 0.0246
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0106 0.0279
Loa Loa (eye worm) hypothetical protein 0.0117 0.0612 0.1127
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0059 0.009
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0274 0.0798
Echinococcus multilocularis sentrin specific protease 1 0.0014 0.0018 0.001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0274 0.0798
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0026 0.0027
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0012 0.0035
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0068 0.0326 0.0859
Toxoplasma gondii hypothetical protein 0.0117 0.0612 0.6063
Plasmodium falciparum carbonic anhydrase 0.0117 0.0612 0.6063
Schistosoma mansoni tsg101-related 0.0057 0.0261 0.0351
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0137 0.0177
Brugia malayi hypothetical protein 0.062 0.3512 0.6567
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0106 0.0948
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0274 0.0798
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0274 0.0798
Leishmania major hypothetical protein, conserved 0.0022 0.006 0.0126
Loa Loa (eye worm) RNA binding protein 0.0132 0.0698 0.1289
Brugia malayi CXXC zinc finger family protein 0.0028 0.0096 0.0158
Trypanosoma cruzi metacaspase, putative 0.0059 0.0274 0.0721
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0026 0.0027
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0129 0.022
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0129 0.022
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0094 0.0477 0.1257
Schistosoma mansoni hypothetical protein 0.0031 0.0114 0.0144
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0468 0.1363
Schistosoma mansoni hypothetical protein 0.0034 0.0129 0.0166
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0217 0.1186 0.165
Brugia malayi Bromodomain containing protein 0.0154 0.0824 0.1524
Echinococcus multilocularis cpg binding protein 0.0034 0.0128 0.0218
Loa Loa (eye worm) hypothetical protein 0.062 0.3512 0.6567
Brugia malayi TAR-binding protein 0.0132 0.0698 0.1288
Trypanosoma cruzi metacaspase, putative 0.0059 0.0274 0.0721
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0117 0.0612 0.1125
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0143 0.0246
Onchocerca volvulus 0.0067 0.032 0.0864
Trypanosoma brucei DNA polymerase kappa, putative 0.011 0.0571 0.1506
Echinococcus multilocularis Kelch repeat type 1 0.0093 0.0469 0.0857
Echinococcus granulosus kelch ECH associated protein 1 0.0092 0.0467 0.0854
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0026 0.0144
Loa Loa (eye worm) mbt repeat family protein 0.0204 0.1114 0.2069
Trichomonas vaginalis hypothetical protein 0.0033 0.0126 0.0366
Trypanosoma brucei beta lactamase 0.0062 0.0294 0.0774
Brugia malayi jmjC domain containing protein 0.0016 0.0026 0.0027
Plasmodium vivax importin-beta 2, putative 0.0029 0.0104 0.0925
Loa Loa (eye worm) Ulp1 protease 0.0074 0.0363 0.066
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0185 0.1002 1
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0014 0.0018 0.0009
Brugia malayi hypothetical protein 0.0068 0.0327 0.0591
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0014 0.0018 0.0055
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0608 0.112
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0143 0.1323
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0086 0.0432 0.4239
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0013 0.0012 0.0121
Schistosoma mansoni hypothetical protein 0.04 0.2243 0.3135
Echinococcus multilocularis polycomb protein SCMH1 0.0204 0.1114 0.2067
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0012
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0059 0.0088
Trypanosoma brucei unspecified product 0.0066 0.0316 0.0831
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0106 0.0948
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0356 0.0646
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0071 0.0056
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Brugia malayi Cell death protein 3 precursor 0.0059 0.0274 0.0491
Echinococcus multilocularis dna polymerase kappa 0.0155 0.0827 0.1529
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0117 0.0612 0.1125
Chlamydia trachomatis replicative DNA helicase 0.0392 0.2195 1
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0107 0.0551 0.1012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.075 0.1039
Toxoplasma gondii hypothetical protein 0.0108 0.0557 0.5508
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0026 0.0021
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.006 0.0158
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0014 0.0018 0.0009
Echinococcus granulosus caspase 8 0.0059 0.0274 0.0491
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0185 0.1002 0.2639
Trypanosoma brucei polo-like protein kinase 0.0092 0.0468 0.1232
Trichomonas vaginalis DNA polymerase eta, putative 0.0155 0.0827 0.2412
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0104 0.0925
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0026 0.007
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0117 0.0612 0.1125
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0468 0.1363
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0468 0.1204
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0018 0.0175
Leishmania major hypothetical protein, conserved 0.0031 0.0114 0.0269
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0071 0.0187
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0698 0.0965
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0142 0.0245
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0052 0.0138
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0233 0.1277 0.2374
Echinococcus multilocularis snurportin 1 0.0313 0.1742 0.3245
Echinococcus multilocularis dna polymerase eta 0.0152 0.0813 0.1502
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.075 0.1385
Schistosoma mansoni gabp alpha 0.0071 0.0343 0.0466
Plasmodium falciparum importin beta, putative 0.0029 0.0104 0.0925
Plasmodium falciparum metacaspase-like protein 0.0059 0.0274 0.2643
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0274 0.0798
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0071 0.0596
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0698 0.0965
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0104 0.0273
Schistosoma mansoni caspase-7 (C14 family) 0.0059 0.0274 0.0369
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0096 0.0487 0.0893
Trichomonas vaginalis dullard protein, putative 0.0013 0.0012 0.0035
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0274 0.0798
Brugia malayi jmjC domain containing protein 0.0016 0.0026 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0274 0.0798
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0143 0.0246
Echinococcus multilocularis muscleblind protein 0.0937 0.5341 1
Loa Loa (eye worm) fli-1 protein 0.0215 0.1175 0.2184
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0143 0.0417
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0468 0.0854
Onchocerca volvulus 0.0028 0.0096 0.0226
Echinococcus multilocularis GPCR, family 2 0.0034 0.0129 0.022
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0071 0.0088
Schistosoma mansoni ran 0.0022 0.0059 0.0067
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0106 0.0133
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0018 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Echinococcus multilocularis geminin 0.0707 0.4012 0.7506
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.075 0.1385
Schistosoma mansoni carbonic anhydrase-related 0.0117 0.0612 0.0844
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0059 0.0473
Loa Loa (eye worm) hypothetical protein 0.0117 0.0612 0.1127
Schistosoma mansoni hypothetical protein 0.0073 0.0356 0.0484
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0018 0.0175
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0094 0.0477 0.1257
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0477 0.1257
Leishmania major importin beta-1 subunit, putative 0.0024 0.0072 0.0157
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0185 0.1002 0.292
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0068 0.0327 0.0591
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0343 0.0621
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0018 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Brugia malayi Fli-1 protein 0.0215 0.1175 0.2183
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0698 0.0965
Brugia malayi polk-prov protein 0.0089 0.0446 0.0814
Loa Loa (eye worm) Ulp1 protease 0.0014 0.0018 0.0012
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0026 0.0027
Echinococcus multilocularis phosphoglycerate kinase 1 0.0185 0.1002 0.1856
Loa Loa (eye worm) hypothetical protein 0.0084 0.0421 0.0768
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0311 0.0422
Schistosoma mansoni hypothetical protein 0.0707 0.4012 0.5621
Loa Loa (eye worm) hypothetical protein 0.0061 0.0284 0.0511
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0217 0.1186 0.2202
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0217 0.1186 0.2202
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.0348 0.0631
Trichomonas vaginalis glutaminase, putative 0.0606 0.3429 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0204 0.1114 0.1549
Echinococcus multilocularis dnaJ subfamily B 0.04 0.2243 0.4186
Onchocerca volvulus 0.0204 0.1114 0.3138
Mycobacterium ulcerans phosphoglycerate kinase 0.0185 0.1002 0.2811
Loa Loa (eye worm) hypothetical protein 0.0068 0.0327 0.0592
Echinococcus multilocularis carbonic anhydrase 0.0117 0.0612 0.1125
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0274 0.0798
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0468 0.1363
Trypanosoma brucei phosphoglycerate kinase 0.0185 0.1002 0.2639
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.0348 0.0631
Schistosoma mansoni sex comb on midleg homolog 0.0204 0.1114 0.1549
Leishmania major DNA polymerase eta, putative 0.0152 0.0813 0.2116
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0143 0.0417
Echinococcus granulosus tar DNA binding protein 0.0132 0.0698 0.1288
Mycobacterium tuberculosis Conserved hypothetical protein 0.0353 0.1968 0.1953
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0059 0.0274 0.2643
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0468 0.1232
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0052 0.0106
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0557 0.3149 1
Schistosoma mansoni hypothetical protein 0.0034 0.0129 0.0166
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0143 0.0246
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0052 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0051
Mycobacterium tuberculosis Conserved hypothetical protein 0.0096 0.0487 0.0469
Brugia malayi ImpB/MucB/SamB family protein 0.0152 0.0813 0.1502
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0026 0.0021
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0067 0.032 0.3107
Echinococcus granulosus carbonic anhydrase 0.0117 0.0612 0.1125
Trypanosoma cruzi ISWI complex protein 0.0031 0.0114 0.03
Leishmania major metacaspase, putative 0.0059 0.0274 0.0691
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.075 0.1385
Leishmania major DNA polymerase kappa, putative 0.011 0.0571 0.1478
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0137 0.0235
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0047 0.0208 0.0277
Echinococcus granulosus SAM and MBT domain containing protein 0.0204 0.1114 0.2067
Trichomonas vaginalis dullard protein, putative 0.0013 0.0012 0.0035
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0669 0.3796 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0104 0.0173
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.011 0.0571 0.0554
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0106 0.0279
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0071 0.0053
Echinococcus multilocularis sentrin specific protease 8 0.0074 0.0363 0.0658
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0078 0.0385 0.0701
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0217 0.1186 0.3124
Schistosoma mansoni glutaminase 0.0606 0.3429 0.4802
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0071 0.0246
Plasmodium vivax sentrin-specific protease 2, putative 0.0014 0.0018 0.0055
Loa Loa (eye worm) hypothetical protein 0.0152 0.0813 0.1504
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0014 0.0018 0.0046
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0059 0.0274 0.0491
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0106 0.0279
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0356 0.0646
Plasmodium falciparum phosphoglycerate kinase 0.0185 0.1002 1
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0274 0.0798
Leishmania major DNA damage repair protein, putative 0.003 0.0106 0.0248
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0233 0.1277 0.2374
Echinococcus multilocularis Protein lozenge 0.006 0.0283 0.0508
Brugia malayi jmjC domain containing protein 0.0016 0.0026 0.0027
Loa Loa (eye worm) glutaminase 0.0606 0.3429 0.6413
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0698 0.0965
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0217 0.1186 0.2203
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0143 0.1429
Entamoeba histolytica phosphoglycerate kinase, putative 0.0185 0.1002 1
Onchocerca volvulus 0.062 0.3512 1
Brugia malayi Bromodomain containing protein 0.0078 0.0384 0.0698
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0064 0.0302 0.0544
Schistosoma mansoni jumonji domain containing protein 0.006 0.028 0.0377
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0026 0.0029
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0052 0.0152
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0143 0.0346
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0071 0.0596
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.0348 0.3477
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0155 0.0827 0.2412
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0143 0.0185
Brugia malayi Muscleblind-like protein 0.0937 0.5341 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0101 0.052 0.0952
Echinococcus granulosus cpg binding protein 0.0034 0.0128 0.0218
Echinococcus granulosus muscleblind protein 0.0937 0.5341 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0052 0.0075
Schistosoma mansoni kinase 0.0047 0.0205 0.0273
Mycobacterium leprae Conserved hypothetical protein 0.0513 0.2896 0.9177
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0143 0.0417
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0012 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0106 0.0279
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0174 0.0304
Plasmodium vivax JmjC domain containing protein 0.0016 0.0026 0.0144
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0018 0.0051
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0313 0.1742 0.3246
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.028 0.0502
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0068 0.0326 0.0859
Giardia lamblia Phosphoglycerate kinase 0.0185 0.1002 1
Echinococcus granulosus polycomb protein SCMH1 0.0204 0.1114 0.2067
Brugia malayi mbt repeat family protein 0.0204 0.1114 0.2067
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0185 0.1002 0.3022
Trypanosoma brucei DNA polymerase IV, putative 0.0155 0.0827 0.2179
Trypanosoma cruzi ISWI complex protein 0.0031 0.0114 0.03
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0014 0.0018 0.0014
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.0551 0.1011
Trypanosoma brucei ISWI complex protein 0.0031 0.0114 0.03
Schistosoma mansoni tsg101-related 0.0046 0.0201 0.0267
Trichomonas vaginalis set domain proteins, putative 0.0526 0.2966 0.865
Treponema pallidum replicative DNA helicase (dnaB) 0.0392 0.2195 1
Entamoeba histolytica Ran family GTPase 0.0022 0.0059 0.0589
Brugia malayi Phosphoglycerate kinase 0.0068 0.0326 0.0589
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0059 0.0274 0.0369
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0014 0.0018 0.0051
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0059 0.0274 0.2643
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0026 0.0027
Schistosoma mansoni cpg binding protein 0.0028 0.0096 0.012
Leishmania major hypothetical protein, conserved 0.0016 0.0026 0.0038
Echinococcus granulosus histone acetyltransferase MYST2 0.0233 0.1277 0.2374
Trypanosoma cruzi metacaspase 5, putative 0.0059 0.0274 0.0721
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0104 0.0273
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0059 0.0155
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0012 0.0001
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0071 0.0056
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0059 0.0473
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.006 0.0158
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0026 0.0029
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0117 0.0612 0.1127
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.052 0.0714
Entamoeba histolytica hypothetical protein 0.0024 0.0072 0.0715
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0072 0.0209
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0074 0.0363 0.0494
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0274 0.0798
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0052 0.0406
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0274 0.2643
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0013 0.0012 0.0032
Brugia malayi jmjC domain containing protein 0.006 0.028 0.0502
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0311 0.0563
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.04 0.1054
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0421 0.0766
Loa Loa (eye worm) hypothetical protein 0.0059 0.0274 0.0492
Leishmania major mitochondrial DNA polymerase beta 0.0669 0.3796 1
Leishmania major phosphoglycerate kinase B, cytosolic 0.0185 0.1002 0.2615
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0446 0.1175
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0129 0.022
Schistosoma mansoni importin beta-1 0.0029 0.0104 0.013
Echinococcus granulosus geminin 0.0707 0.4012 0.7506
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0137 0.0235
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0392 0.2195 0.6344
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0468 0.1232
Trypanosoma brucei DNA polymerase IV, putative 0.0155 0.0827 0.2179
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0059 0.0155
Echinococcus granulosus phosphoglycerate kinase 1 0.0185 0.1002 0.1856
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0026 0.0144
Trichomonas vaginalis Sentrin-specific protease, putative 0.0074 0.0363 0.1058
Trypanosoma brucei phosphoglycerate kinase 0.0068 0.0326 0.0859
Brugia malayi jmjC domain containing protein 0.0065 0.0311 0.0561
Trypanosoma brucei metacaspase MCA3 0.0059 0.0274 0.0721
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0468 0.1288
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0421 0.0575
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0217 0.1186 0.165
Plasmodium falciparum sentrin-specific protease 1 0.0014 0.0018 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0198 0.0578
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0129 0.022
Mycobacterium ulcerans hypothetical protein 0.0353 0.1968 0.5673
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0059 0.0274 0.0491
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0018 0.0175
Schistosoma mansoni hypothetical protein 0.1247 0.7129 1
Brugia malayi PHD-finger family protein 0.0052 0.0236 0.042
Trichomonas vaginalis dullard protein, putative 0.0013 0.0012 0.0035
Loa Loa (eye worm) hypothetical protein 0.0013 0.0012 0.0002
Echinococcus granulosus fetal alzheimer antigen falz 0.0047 0.0208 0.0368
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0071 0.0596
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0356 0.0645
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0123 0.0645 0.1187
Loa Loa (eye worm) hypothetical protein 0.0101 0.052 0.0954
Loa Loa (eye worm) runx1 0.006 0.0283 0.0509
Entamoeba histolytica deoxycytidyl transferase, putative 0.0096 0.0487 0.4864
Schistosoma mansoni hypothetical protein 0.0707 0.4012 0.5621
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0014 0.0018 0.0046
Loa Loa (eye worm) hypothetical protein 0.0204 0.1114 0.2069
Brugia malayi mbt repeat family protein 0.0204 0.1114 0.2067
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0822 0.4677 0.8754
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0669 0.3796 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0135 0.023
Loa Loa (eye worm) TAR-binding protein 0.0132 0.0698 0.1289
Trypanosoma brucei carbonic anhydrase-like protein 0.0217 0.1186 0.3124
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0052 0.0075
Schistosoma mansoni hypothetical protein 0.0093 0.0469 0.0643
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0462 0.2599 0.4854
Trypanosoma cruzi hypothetical protein 0.0074 0.0363 0.0956
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.011 0.0571 0.1478
Schistosoma mansoni hypothetical protein 0.0117 0.0612 0.0844
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0106 0.0279
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0074 0.0363 0.1058
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0827 0.2179
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0052 0.0138
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.032 0.0433
Onchocerca volvulus 0.0481 0.2712 0.771
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0185 0.1002 0.292
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0274 0.0798
Mycobacterium ulcerans DNA polymerase IV 0.0155 0.0827 0.2294
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0283 0.274
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0135 0.023
Brugia malayi RNA recognition motif domain containing protein 0.0132 0.0698 0.1288
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0468 0.0856
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0185 0.1002 0.2639
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.013 0.0683 0.0666
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0071 0.0088
Loa Loa (eye worm) carbonic anhydrase 3 0.0217 0.1186 0.2203
Echinococcus granulosus dnaJ subfamily B 0.04 0.2243 0.4186
Loa Loa (eye worm) MBCTL1 0.0233 0.1277 0.2375
Giardia lamblia DINP protein human, muc B family 0.011 0.0571 0.5653
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0468 0.1363
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.075 0.1387
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.0348 0.0631
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.0551 0.1011
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0052 0.0522
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0135 0.0173
Echinococcus granulosus dna polymerase kappa 0.0155 0.0827 0.1529
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0106 0.0279
Loa Loa (eye worm) hypothetical protein 0.0117 0.0612 0.1127
Onchocerca volvulus 0.0084 0.0421 0.1154
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0468 0.1363
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0446 0.1175
Schistosoma mansoni ran 0.0022 0.0059 0.0067
Loa Loa (eye worm) hypothetical protein 0.0937 0.5341 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0101 0.052 0.0952
Echinococcus granulosus importin subunit beta 1 0.0029 0.0104 0.0172
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0014 0.0018 0.0055
Mycobacterium ulcerans glutaminase 0.0606 0.3429 1
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0014 0.0018 0.001
Brugia malayi Ets-domain containing protein 0.0071 0.0343 0.0621
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0129 0.0222
Echinococcus granulosus carbonic anhydrase II 0.0217 0.1186 0.2202
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0012 0.0035
Onchocerca volvulus Cell death protein 3 homolog 0.0059 0.0274 0.0733
Schistosoma mansoni carbonic anhydrase-related 0.0117 0.0612 0.0844
Trypanosoma brucei metacaspase MCA2 0.0059 0.0274 0.0721
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1353 0.774 0.7735
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0058 0.0086
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0059 0.0088
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0014 0.0018 0.0051
Trypanosoma cruzi metacaspase, putative 0.0059 0.0274 0.0721
Schistosoma mansoni Replicative DNA helicase 0.0392 0.2195 0.3068
Echinococcus granulosus phd:f box containing protein 0.0016 0.0026 0.0027
Brugia malayi glutaminase DH11.1 0.0606 0.3429 0.6412
Schistosoma mansoni zinc finger protein 0.0031 0.0114 0.0144
Echinococcus granulosus kelch ECH associated protein 1 like 0.0092 0.0467 0.0854
Treponema pallidum phosphoglycerate kinase 0.0185 0.1002 0.4431
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.04 0.1054
Brugia malayi Ets-domain containing protein 0.0071 0.0343 0.0621
Echinococcus granulosus dna polymerase eta 0.0152 0.0813 0.1502
Schistosoma mansoni caspase-3 (C14 family) 0.0059 0.0274 0.0369
Brugia malayi ImpB/MucB/SamB family protein 0.0096 0.0487 0.0891
Echinococcus multilocularis caspase 0.0059 0.0274 0.0491

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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