Detailed information for compound 1844928

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 503.168 | Formula: C15H13Br2N5O3S
  • H donors: 1 H acceptors: 3 LogP: 2.28 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)NC1=NN(C2(S1)C(=NN(C2=O)c1ccc(cc1Br)Br)C)C(=O)C
  • InChi: 1S/C15H13Br2N5O3S/c1-7-15(22(9(3)24)20-14(26-15)18-8(2)23)13(25)21(19-7)12-5-4-10(16)6-11(12)17/h4-6H,1-3H3,(H,18,20,23)
  • InChiKey: AXEWLRDJCQDJCT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0034 0.0133 0.0217
Brugia malayi Bromodomain containing protein 0.0029 0.0099 0.0176
Echinococcus granulosus tm gpcr rhodopsin 0.0178 0.1011 0.1525
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0013 0.0002 0.0001
Brugia malayi RNA, U transporter 1 0.0077 0.0396 0.0707
Schistosoma mansoni DNA polymerase eta 0.0026 0.0081 0.012
Onchocerca volvulus 0.0023 0.0067 0.0639
Echinococcus multilocularis serotonin receptor 0.0178 0.1011 0.101
Brugia malayi hypothetical protein 0.0039 0.0164 0.0293
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0178 0.1011 0.1804
Schistosoma mansoni biogenic amine receptor 0.0178 0.1011 0.1525
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0077 0.0396 0.1284
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0002
Brugia malayi Steroid receptor seven-up type 2 0.0013 0.0002 0.0004
Schistosoma mansoni hypothetical protein 0.0031 0.011 0.0164
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Schistosoma mansoni neuropeptide receptor 0.0178 0.1011 0.1525
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.1199 0.2122
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0013 0.0002 0.0001
Onchocerca volvulus 0.0178 0.1011 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0092 0.0164
Echinococcus multilocularis neuropeptide Y receptor 0.0178 0.1011 0.101
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.006 0.0288 0.0513
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus multilocularis neuropeptides capa receptor 0.0178 0.1011 0.101
Brugia malayi Cathepsin L-like precursor 0.0024 0.0068 0.0121
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Schistosoma mansoni bromodomain containing protein 0.0047 0.0213 0.032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.1011 0.101
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0021 0.0053 0.0078
Loa Loa (eye worm) bromodomain containing protein 0.0013 0.0004 0.0007
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0178 0.1011 0.1804
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0034 0.004
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0014 0.0011 0.00000061743
Echinococcus granulosus inositol monophosphatase 1 0.0025 0.0073 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.076 0.1338
Brugia malayi Serotonin receptor 0.0178 0.1011 0.1804
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0025 0.0073 0.1063
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.033 0.0497
Loa Loa (eye worm) hypothetical protein 0.0109 0.0592 0.1057
Schistosoma mansoni hypothetical protein 0.0046 0.0204 0.0307
Brugia malayi hypothetical protein 0.0028 0.0092 0.0164
Schistosoma mansoni hypothetical protein 0.0051 0.0234 0.0352
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0002 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0178 0.1011 0.1525
Schistosoma mansoni opsin-like receptor 0.0178 0.1011 0.1525
Schistosoma mansoni adenoreceptor 0.0178 0.1011 0.1525
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0014 0.0011 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0391 0.6532
Loa Loa (eye worm) hypothetical protein 0.0039 0.016 0.0286
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Leishmania major cathepsin L-like protease 0.0024 0.0068 0.0076
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0109 0.0592 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0023 0.0067 0.0119
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0244 0.1415 0.2509
Brugia malayi cathepsin L-like precursor 0.0016 0.002 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0002 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) steroid hormone receptor 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0074 0.0374 0.0668
Schistosoma mansoni survival motor neuron protein 0.0071 0.0355 0.0533
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0067 0.033 0.0329
Onchocerca volvulus 0.0076 0.0391 0.3852
Onchocerca volvulus Protein cycle homolog 0.0028 0.0093 0.09
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0053 0.0075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0095
Onchocerca volvulus 0.0023 0.0067 0.0639
Onchocerca volvulus 0.0178 0.1011 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0017 0.0026 0.0026
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0038 0.0154 0.2449
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0046 0.0204 0.0364
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.0391 0.1265
Onchocerca volvulus 0.0178 0.1011 1
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.002 0.0028
Echinococcus granulosus peptidase Clp S14 family 0.0072 0.0362 0.0544
Echinococcus granulosus tachykinin peptides receptor 99D 0.0178 0.1011 0.1525
Trypanosoma cruzi cysteine peptidase, putative 0.009 0.0475 0.0828
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0489 0.2912 1
Trichomonas vaginalis importin beta-1, putative 0.0022 0.0058 0.0083
Brugia malayi Tachykinin-like peptides receptor 99D 0.0178 0.1011 0.1804
Loa Loa (eye worm) ctsf protein 0.0024 0.0068 0.0121
Echinococcus granulosus biogenic amine 5HT receptor 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0027 0.0089 0.016
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0178 0.1011 0.101
Echinococcus granulosus neuropeptides capa receptor 0.0178 0.1011 0.1525
Brugia malayi Muscleblind-like protein 0.0112 0.0608 0.1084
Schistosoma mansoni opsin-like receptor 0.0178 0.1011 0.1525
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0072 0.0362 0.1165
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0178 0.1011 0.101
Brugia malayi AKH receptor 0.0178 0.1011 0.1804
Brugia malayi Cathepsin L-like precursor 0.0024 0.0068 0.0121
Loa Loa (eye worm) transcription factor SMAD2 0.0078 0.0398 0.071
Mycobacterium ulcerans aldehyde dehydrogenase 0.008 0.0411 0.5732
Leishmania major cathepsin L-like protease 0.0024 0.0068 0.0076
Brugia malayi Cathepsin L-like precursor 0.0024 0.0068 0.0121
Echinococcus granulosus GTP binding nuclear protein Ran 0.002 0.0046 0.0067
Plasmodium falciparum ataxin-2 like protein, putative 0.0018 0.0032 0.0038
Onchocerca volvulus 0.0039 0.0164 0.1606
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0178 0.1011 0.101
Onchocerca volvulus 0.0178 0.1011 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0391 0.0697
Onchocerca volvulus 0.0178 0.1011 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0247 0.0441
Leishmania major hypothetical protein, conserved 0.0076 0.0391 0.0654
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Echinococcus granulosus zinc finger protein 0.0015 0.0013 0.0017
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0075 0.0382 0.0681
Brugia malayi hypothetical protein 0.0051 0.0234 0.0418
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0929 0.5607 0.8463
Brugia malayi hypothetical protein 0.0116 0.063 0.1124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0013 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0031 0.011 0.0164
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0178 0.1011 0.1525
Echinococcus granulosus tm gpcr rhodopsin 0.0178 0.1011 0.1525
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.1011 0.1525
Loa Loa (eye worm) G-protein coupled receptor 0.0178 0.1011 0.1804
Onchocerca volvulus 0.0024 0.0068 0.0651
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0002 0.0001
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0024 0.0068 0.0067
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0089 0.014
Entamoeba histolytica hypothetical protein 0.0051 0.0234 0.0398
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.1011 0.1525
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.002 0.0015
Echinococcus multilocularis G-protein coupled receptor, putative 0.0178 0.1011 0.101
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0179 0.0299
Plasmodium falciparum importin beta, putative 0.0027 0.0089 0.014
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0027 0.0088 0.0131
Brugia malayi Papain family cysteine protease containing protein 0.0024 0.0068 0.0121
Onchocerca volvulus 0.0178 0.1011 1
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0116 0.063 0.1124
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0038 0.0154 0.0254
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0929 0.5607 0.5606
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0068 0.0101
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0109 0.0592 1
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.0391 0.1265
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.002 0.0046 0.0081
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.1011 0.101
Echinococcus granulosus biogenic amine 5HT receptor 0.0178 0.1011 0.1525
Echinococcus multilocularis protein dispatched 1 0.0036 0.0144 0.0143
Toxoplasma gondii hypothetical protein 0.0039 0.0164 0.0272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0013 0.0002 0.0004
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0178 0.1011 0.1525
Echinococcus multilocularis dna polymerase eta 0.0026 0.0081 0.0079
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0017 0.0026 0.0246
Loa Loa (eye worm) hypothetical protein 0.0145 0.0812 0.1448
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0013 0.0002 0.0004
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.006 0.0288 0.0433
Plasmodium vivax vivapain-2 0.0024 0.0068 0.0101
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0178 0.1011 0.1525
Echinococcus granulosus importin subunit beta 1 0.0027 0.0089 0.0133
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0002 0.0001
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0178 0.1011 0.1525
Schistosoma mansoni tyrosine kinase 0.0179 0.1019 0.1537
Brugia malayi Protein kinase domain containing protein 0.0181 0.1032 0.1841
Onchocerca volvulus 0.0024 0.0068 0.0651
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0053 0.0075
Brugia malayi Serotonin receptor 0.0178 0.1011 0.1804
Loa Loa (eye worm) PHD-finger family protein 0.0015 0.0018 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0068 0.0101
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Leishmania major cathepsin L-like protease 0.0024 0.0068 0.0076
Loa Loa (eye worm) hypothetical protein 0.006 0.0288 0.0513
Onchocerca volvulus 0.0024 0.0068 0.0651
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0032 0.0121 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0178 0.1011 0.101
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0045 0.0197 0.0295
Mycobacterium leprae Probable lipase LipE 0.0076 0.0391 0.6532
Schistosoma mansoni ran 0.002 0.0046 0.0067
Onchocerca volvulus Glucosylceramidase homolog 0.0137 0.076 0.7512
Onchocerca volvulus 0.0178 0.1011 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0109 0.0592 0.1039
Brugia malayi GnHR receptor homolog 0.0178 0.1011 0.1804
Echinococcus granulosus ecdysone induced protein 78C 0.0013 0.0002 0.0001
Brugia malayi hypothetical protein 0.0028 0.0093 0.0166
Onchocerca volvulus 0.0076 0.0391 0.3852
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.004 0.0165 0.0295
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0391 0.0678
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0178 0.1011 0.1525
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0034 0.0133 0.0217
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0071 0.0355 0.0632
Entamoeba histolytica hypothetical protein 0.0051 0.0234 0.0398
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0131 0.0213
Echinococcus granulosus Niemann Pick C1 protein 0.0074 0.0374 0.0563
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0017 0.0026 0.0025
Echinococcus granulosus microtubule associated protein 2 0.1096 0.6625 1
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus granulosus survival motor neuron protein 1 0.0346 0.2038 0.3076
Schistosoma mansoni importin beta-1 0.0027 0.0089 0.0133
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0058 0.0083
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0178 0.1011 0.1525
Schistosoma mansoni hypothetical protein 0.0015 0.0018 0.0025
Echinococcus multilocularis neuropeptide Y receptor 0.0178 0.1011 0.101
Echinococcus granulosus 7tm_1 domain containing protein 0.0178 0.1011 0.1525
Schistosoma mansoni hypothetical protein 0.029 0.17 0.2564
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.1199 0.2122
Echinococcus multilocularis neuropeptide receptor 0.0178 0.1011 0.101
Echinococcus granulosus neuropeptides capa receptor 0.0178 0.1011 0.1525
Onchocerca volvulus 0.0178 0.1011 1
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0115 0.0629 0.1104
Mycobacterium ulcerans beta-lactamase 0.0076 0.0391 0.5441
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0929 0.5607 1
Mycobacterium leprae conserved hypothetical protein 0.0017 0.0026 0.0246
Schistosoma mansoni intermediate filament proteins 0.0023 0.0067 0.0099
Echinococcus multilocularis L aminoadipate semialdehyde 0.006 0.0288 0.0287
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0021 0.0053 0.0078
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0028 0.0093 0.0166
Schistosoma mansoni transcription factor LCR-F1 0.0051 0.0234 0.0352
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0391 0.0678
Brugia malayi Niemann-Pick C1 protein precursor 0.0074 0.0374 0.0668
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.0382 0.0662
Echinococcus multilocularis muscleblind protein 0.0112 0.0608 0.0607
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0074 0.0374 0.0649
Schistosoma mansoni ran 0.002 0.0046 0.0067
Schistosoma mansoni aldehyde dehydrogenase 0.008 0.0411 0.0619
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0013 0.0002 0.0004
Echinococcus multilocularis Niemann Pick C1 protein 0.0074 0.0374 0.0373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Schistosoma mansoni amine GPCR 0.0178 0.1011 0.1525
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0178 0.1011 0.1525
Onchocerca volvulus 0.0076 0.0391 0.3852
Schistosoma mansoni hypothetical protein 0.0046 0.0204 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0068 0.0101
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0178 0.1011 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0109 0.0592 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.1011 0.1525
Schistosoma mansoni patched 1 0.0032 0.0117 0.0174
Brugia malayi PHD-finger family protein 0.0019 0.0037 0.0066
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0109 0.0592 0.1039
Loa Loa (eye worm) hypothetical protein 0.0112 0.0608 0.1084
Schistosoma mansoni alpha-1 adrenergic receptor 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0028 0.0092 0.0164
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0929 0.5607 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.002 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0391 0.0678
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0293
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.0391 0.1265
Loa Loa (eye worm) hypothetical protein 0.0023 0.0067 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0013 0.0002 0.0004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0025 0.0073 0.011
Schistosoma mansoni biogenic amine receptor 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0058
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0391 0.0678
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Brugia malayi glutathione reductase 0.0034 0.0131 0.0233
Loa Loa (eye worm) hypothetical protein 0.0028 0.0092 0.0164
Echinococcus multilocularis replication factor c subunit 1 0.0014 0.0011 0.001
Schistosoma mansoni DNA ligase IV 0.0014 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus granulosus g protein coupled receptor 0.0178 0.1011 0.1525
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0075 0.0382 0.0638
Echinococcus granulosus peptide allatostatin:somatostatin 0.0178 0.1011 0.1525
Plasmodium vivax importin-beta 2, putative 0.0027 0.0089 0.014
Schistosoma mansoni hypothetical protein 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.0208
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0046 0.0204 0.0307
Echinococcus granulosus replication factor c subunit 1 0.0014 0.0011 0.0015
Schistosoma mansoni hypothetical protein 0.0031 0.011 0.0164
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0929 0.5607 1
Brugia malayi Cathepsin L-like precursor 0.0024 0.0068 0.0121
Brugia malayi nuclear receptor NHR-88 0.0013 0.0002 0.0004
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0178 0.1011 0.101
Brugia malayi Thioredoxin reductase 0.0034 0.0131 0.0233
Brugia malayi Calcitonin receptor-like protein seb-1 0.0145 0.0812 0.1448
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0028 0.0093 0.0139
Onchocerca volvulus 0.0024 0.0068 0.0651
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0017 0.0026 0.0205
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0109 0.0592 1
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0017 0.0026 0.0026
Echinococcus granulosus neuropeptide receptor 0.0288 0.1684 0.2541
Schistosoma mansoni aldehyde dehydrogenase 0.008 0.0411 0.0619
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0145 0.0812 0.1448
Loa Loa (eye worm) inositol-1 0.0025 0.0073 0.013
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0109 0.0592 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.1011 0.1525
Onchocerca volvulus 0.0178 0.1011 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0022 0.0057 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.1011 0.1525
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0178 0.1011 0.101
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0059 0.0285 0.049
Echinococcus multilocularis GTP binding nuclear protein Ran 0.002 0.0046 0.0044
Echinococcus multilocularis orexin receptor type 2 0.0178 0.1011 0.101
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0178 0.1011 0.101
Brugia malayi Pax transcription activation domain interacting protein 0.0014 0.0011 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0025 0.0073 0.011
Plasmodium vivax glutathione reductase, putative 0.0034 0.0131 0.0213
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0391 0.0588
Schistosoma mansoni biogenic amine (5HT) receptor 0.0178 0.1011 0.1525
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0014 0.0011 0.00000061743
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0002 0.0004
Schistosoma mansoni neuropeptide receptor 0.0178 0.1011 0.1525
Mycobacterium ulcerans lipase LipD 0.0076 0.0391 0.5441
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0021 0.0053 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0053 0.0095
Echinococcus granulosus geminin 0.0443 0.2631 0.397
Brugia malayi topoisomerase 0.0014 0.0011 0.002
Echinococcus multilocularis sex peptide receptor 0.0178 0.1011 0.101
Schistosoma mansoni amine GPCR 0.0178 0.1011 0.1525
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0068 0.0101
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0077 0.0396 0.1284
Plasmodium vivax vivapain-2 0.0024 0.0068 0.0101
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0075 0.0381 0.0574
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0013 0.0002 0.0001
Loa Loa (eye worm) TK/FAK protein kinase 0.0181 0.1032 0.1841
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.1011 0.101
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0046 0.0061
Echinococcus multilocularis g protein coupled receptor 0.0178 0.1011 0.101
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0178 0.1011 0.101
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0189 0.0187
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0002 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0244 0.1415 0.2509
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.076 0.1338
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0075 0.0382 0.0575
Loa Loa (eye worm) hypothetical protein 0.0076 0.0391 0.0697
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.002 0.0015
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0017 0.0026 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0029 0.0099 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus multilocularis g-protein coupled receptor 0.0178 0.1011 0.101
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0013 0.0002 0.0004
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0178 0.1011 0.1525
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0013 0.0002 0.0001
Schistosoma mansoni inositol monophosphatase 0.0025 0.0073 0.0109
Brugia malayi Melatonin receptor type 1A 0.0178 0.1011 0.1804
Trypanosoma cruzi cruzipain precursor, putative 0.009 0.0475 0.0828
Onchocerca volvulus Cathepsin F homolog 0.0024 0.0068 0.0651
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0178 0.1011 0.1525
Schistosoma mansoni neuropeptide F-like receptor 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0178 0.1011 0.1804
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0032 0.0121 0.0181
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.029 0.17 0.3031
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi hypothetical protein 0.0018 0.0032 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.1011 0.1525
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0077 0.0396 0.1284
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.1199 0.2122
Echinococcus multilocularis snurportin 1 0.029 0.17 0.1699
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.1011 0.1525
Schistosoma mansoni hypothetical protein 0.0071 0.0355 0.0533
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0053 0.0075
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0025 0.0073 0.011
Onchocerca volvulus Cathepsin L homolog 0.0024 0.0068 0.0651
Onchocerca volvulus 0.0024 0.0068 0.0651
Echinococcus multilocularis g protein coupled receptor 0.0178 0.1011 0.101
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.1199 0.2122
Mycobacterium tuberculosis Conserved hypothetical protein 0.0128 0.0709 0.2367
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0075 0.0382 0.0662
Loa Loa (eye worm) thioredoxin reductase 0.0034 0.0131 0.0233
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0013 0.0002 0.0004
Schistosoma mansoni zinc finger protein 0.0015 0.0013 0.0017
Echinococcus granulosus hypothetical protein 0.0178 0.1011 0.1525
Echinococcus granulosus g-protein coupled receptor 0.0178 0.1011 0.1525
Brugia malayi G-protein coupled receptor 0.0178 0.1011 0.1804
Onchocerca volvulus 0.0071 0.0355 0.3492
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi G-protein coupled receptor 0.0178 0.1011 0.1804
Mycobacterium tuberculosis Probable reductase 0.0077 0.0396 0.1284
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.008 0.0411 0.041
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0024 0.0068 0.0121
Brugia malayi ORL1-like opioid receptor 0.0178 0.1011 0.1804
Brugia malayi hypothetical protein 0.0014 0.0011 0.002
Loa Loa (eye worm) fibroinase 0.0024 0.0068 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0117 0.0188
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Echinococcus granulosus cathepsin l1 0.0016 0.002 0.0028
Trichomonas vaginalis replication factor C large subunit, putative 0.0014 0.0011 0.00000061743
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0051 0.0234 0.0352
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0021 0.0053 0.0052
Trypanosoma cruzi major cysteine proteinase, putative 0.0071 0.0357 0.0617
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0077 0.0396 0.1284
Toxoplasma gondii ABC1 family protein 0.0076 0.0391 0.0678
Schistosoma mansoni hypothetical protein 0.0031 0.011 0.0164
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.0391 0.0697
Schistosoma mansoni peptidase Clp (S14 family) 0.0109 0.0592 0.0893
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.0382 0.0662
Echinococcus multilocularis ecdysone induced protein 78C 0.0013 0.0002 0.0001
Echinococcus granulosus g protein coupled receptor 0.0178 0.1011 0.1525
Onchocerca volvulus 0.0178 0.1011 1
Onchocerca volvulus Huntingtin homolog 0.0116 0.063 0.6222
Brugia malayi neuropeptide F receptor 0.0178 0.1011 0.1804
Schistosoma mansoni neuropeptide receptor 0.0178 0.1011 0.1525
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0053 0.0075
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.0391 0.0697
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.0391 0.1265
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0178 0.1011 0.1804
Toxoplasma gondii thioredoxin reductase 0.0034 0.0131 0.0213
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0109 0.0592 0.833
Echinococcus granulosus neuropeptide Y receptor 0.0178 0.1011 0.1525
Schistosoma mansoni biogenic amine receptor 0.0178 0.1011 0.1525
Mycobacterium tuberculosis Conserved protein 0.0076 0.0391 0.1265
Brugia malayi follicle stimulating hormone receptor 0.0178 0.1011 0.1804
Echinococcus granulosus Protein patched homolog 1 0.0032 0.0117 0.0174
Echinococcus granulosus muscleblind protein 0.0112 0.0608 0.0916
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0032 0.0121 0.0181
Echinococcus granulosus fmrfamide receptor 0.0178 0.1011 0.1525
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0058 0.0083
Echinococcus multilocularis somatostatin receptor 0.0178 0.1011 0.101
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0068 0.0101
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0178 0.1011 0.1804
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus multilocularis peptidase Clp (S14 family) 0.0072 0.0362 0.0361
Loa Loa (eye worm) hypothetical protein 0.0076 0.0391 0.0697
Echinococcus multilocularis survival motor neuron protein 1 0.0346 0.2038 0.2037
Brugia malayi steroid hormone receptor 0.0013 0.0002 0.0004
Brugia malayi Inositol-1 0.0025 0.0073 0.013
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus granulosus sterol regulatory element binding protein 0.0032 0.0117 0.0174
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0178 0.1011 0.101
Loa Loa (eye worm) beta-lactamase 0.0076 0.0391 0.0697
Echinococcus granulosus somatostatin receptor 0.0178 0.1011 0.1525
Onchocerca volvulus Huntingtin homolog 0.0116 0.063 0.6222
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0025 0.0073 0.011
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0391 0.0678
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Echinococcus multilocularis cathepsin L cysteine protease 0.0024 0.0068 0.0067
Plasmodium falciparum cysteine proteinase falcipain 3 0.0024 0.0068 0.0101
Schistosoma mansoni hypothetical protein 0.0099 0.0531 0.0799
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0025 0.0073 0.0085
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.008 0.0411 0.0691
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.076 0.1338
Mycobacterium ulcerans aldehyde dehydrogenase 0.008 0.0411 0.5732
Schistosoma mansoni lamin 0.0023 0.0067 0.0099
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0025 0.0073 0.011
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0036
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.008 0.0411 0.0619
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0046 0.0061
Schistosoma mansoni hypothetical protein 0.0443 0.2631 0.397
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0013 0.0002 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0024 0.0068 0.0101
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0017 0.0026 0.0246
Trypanosoma cruzi DNA polymerase eta, putative 0.0018 0.0034 0.004
Loa Loa (eye worm) hypothetical protein 0.0031 0.011 0.0196
Echinococcus multilocularis dro:myosuppressin receptor 0.0178 0.1011 0.101
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Leishmania major trypanothione reductase 0.0034 0.0131 0.0188
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0391 0.0678
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.1011 0.1525
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.0089 0.014
Mycobacterium ulcerans hypothetical protein 0.0076 0.0391 0.5441
Loa Loa (eye worm) hypothetical protein 0.0112 0.0608 0.1084
Loa Loa (eye worm) intermediate filament protein 0.0023 0.0067 0.0119
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.0391 0.1265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0024 0.0068 0.0067
Entamoeba histolytica hypothetical protein 0.0017 0.0026 0.0026
Schistosoma mansoni neuropeptide F-like receptor 0.0178 0.1011 0.1525
Echinococcus granulosus nibrin 0.0014 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Onchocerca volvulus 0.0178 0.1011 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0002 0.0004
Brugia malayi Importin beta-1 subunit 0.0027 0.0089 0.016
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0034 0.0131 0.0363
Toxoplasma gondii ATPase, AAA family protein 0.0014 0.0011 0.00000061743
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0002 0.0004
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0209 0.1199 0.2138
Trypanosoma cruzi cysteine peptidase, putative 0.009 0.0475 0.0828
Echinococcus multilocularis cathepsin L cysteine protease 0.0024 0.0068 0.0067
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.0391 0.1265
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Echinococcus multilocularis expressed conserved protein 0.0069 0.0347 0.0346
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.002 0.0046 0.0061
Schistosoma mansoni microtubule-associated protein tau 0.1096 0.6625 1
Loa Loa (eye worm) glutathione reductase 0.0034 0.0131 0.0233
Brugia malayi MH2 domain containing protein 0.0078 0.0398 0.071
Entamoeba histolytica hypothetical protein 0.0022 0.0058 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.0144 0.0805 0.1419
Trypanosoma brucei PAB1-binding protein , putative 0.0018 0.0032 0.0038
Brugia malayi Intermediate filament tail domain containing protein 0.0023 0.0067 0.0119
Echinococcus granulosus orexin receptor type 2 0.0178 0.1011 0.1525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0178 0.1011 0.1525
Mycobacterium tuberculosis Probable oxidoreductase 0.0086 0.0449 0.1467
Echinococcus granulosus neuropeptide receptor A26 0.0483 0.2881 0.4347
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.033 0.0497
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0032 0.0117 0.0208
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Echinococcus granulosus sex peptide receptor 0.0178 0.1011 0.1525
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0013 0.0002 0.0004
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0178 0.1011 0.1525
Leishmania major hypothetical protein, conserved 0.0018 0.0032 0.0012
Loa Loa (eye worm) melatonin receptor type 1A 0.0178 0.1011 0.1804
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0013 0.0002 0.0004
Onchocerca volvulus 0.006 0.0288 0.2831
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Schistosoma mansoni lamin 0.0023 0.0067 0.0099
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0178 0.1011 0.1804
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0178 0.1011 0.1804
Plasmodium vivax thioredoxin reductase, putative 0.0034 0.0131 0.0213
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0178 0.1011 0.101
Leishmania major cysteine peptidase A (CPA) 0.0024 0.0068 0.0076
Brugia malayi Cathepsin L-like precursor 0.0016 0.002 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0013 0.0002 0.0004
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0075 0.0382 0.0381
Entamoeba histolytica hypothetical protein 0.0051 0.0234 0.0398
Plasmodium vivax ataxin-2 like protein, putative 0.0018 0.0032 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.076 0.1338
Echinococcus multilocularis inositol monophosphatase 1 0.0025 0.0073 0.0072
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0025 0.0073 0.0885
Echinococcus multilocularis geminin 0.0443 0.2631 0.263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Toxoplasma gondii hypothetical protein 0.0038 0.0154 0.0254
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.002 0.0046 0.8182
Onchocerca volvulus 0.0178 0.1011 1
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0017 0.0026 0.0246
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0929 0.5607 1
Schistosoma mansoni RAR-like nuclear receptor 0.0013 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0045 0.0197 0.0195
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.1011 0.1525
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.0382 0.0662
Trypanosoma cruzi cysteine peptidase, putative 0.009 0.0475 0.0828
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus granulosus FTZ F1 alpha 0.0013 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Onchocerca volvulus Cathepsin L homolog 0.0024 0.0068 0.0651
Echinococcus granulosus neuropeptide receptor 0.0178 0.1011 0.1525
Leishmania major GTP-binding protein, putative 0.002 0.0046 0.0036
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0178 0.1011 0.1804
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.002 0.0046 0.0061
Brugia malayi putative neuropeptide receptor NPR1 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0178 0.1011 0.101
Leishmania major DNA polymerase eta, putative 0.0018 0.0034 0.0014
Schistosoma mansoni neuropeptide receptor 0.0288 0.1684 0.2541
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.1011 0.101
Schistosoma mansoni coup transcription factor 0.0013 0.0002 0.0001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0032 0.0121 0.0217
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi G protein-coupled receptor 0.0178 0.1011 0.1804
Brugia malayi DKFZp564C0469 protein 0.0014 0.0011 0.002
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0929 0.5607 1
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0929 0.5607 1
Echinococcus granulosus cathepsin l1 0.0024 0.0068 0.0101
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0075 0.0382 0.0575
Echinococcus multilocularis muscleblind protein 1 0.0112 0.0608 0.0607
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0086 0.0449 0.1467
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus multilocularis G protein coupled receptor 139 0.0288 0.1684 0.1683
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.1011 0.1525
Toxoplasma gondii LsmAD domain-containing protein 0.0018 0.0032 0.0038
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus granulosus L aminoadipate semialdehyde 0.006 0.0288 0.0433
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.1011 0.1525
Echinococcus granulosus neuropeptide Y receptor 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus multilocularis neuropeptide receptor 0.0288 0.1684 0.1683
Echinococcus granulosus thioredoxin glutathione reductase 0.0034 0.0131 0.0195
Leishmania major cathepsin L-like protease 0.0024 0.0068 0.0076
Echinococcus multilocularis allatostatin A receptor 0.0178 0.1011 0.101
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.033 0.0497
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.0391 0.5441
Trypanosoma brucei DNA polymerase eta, putative 0.0026 0.0081 0.0124
Brugia malayi neuropeptide F receptor 0.0178 0.1011 0.1804
Echinococcus multilocularis microtubule associated protein 2 0.1096 0.6625 0.6624
Onchocerca volvulus 0.0024 0.0068 0.0651
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.1199 0.2122
Leishmania major cathepsin L-like protease 0.009 0.0475 0.0805
Brugia malayi RE15519p 0.0178 0.1011 0.1804
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0002 0.0001
Echinococcus multilocularis neuropeptide FF receptor 2 0.0178 0.1011 0.101
Entamoeba histolytica cysteine protease, putative 0.0024 0.0068 0.0101
Loa Loa (eye worm) neuropeptide F receptor 0.0178 0.1011 0.1804
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0044 0.0195 0.0328
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.0391 0.0588
Echinococcus granulosus dro:myosuppressin receptor 0.0178 0.1011 0.1525
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0929 0.5607 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0178 0.1011 1
Onchocerca volvulus 0.0178 0.1011 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0109 0.0592 0.1039
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.002 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0036
Onchocerca volvulus 0.0024 0.0068 0.0651
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0068 0.0101
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0391 0.0678
Loa Loa (eye worm) hypothetical protein 0.0024 0.0068 0.0121
Echinococcus multilocularis ubiquitin specific protease 41 0.0021 0.0053 0.0052
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0046 0.0204 0.0307
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0929 0.5607 0.8463
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.0391 0.039
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.1199 0.2122
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0929 0.5607 1
Echinococcus multilocularis fmrfamide receptor 0.0178 0.1011 0.101
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0017 0.0026 0.0038
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.033 0.0497
Brugia malayi G protein-coupled receptor F59B2.13 0.0178 0.1011 0.1804
Brugia malayi intermediate filament protein 0.0023 0.0067 0.0119
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0027 0.0088 0.0087
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0178 0.1011 0.1525
Mycobacterium ulcerans hypothetical protein 0.0128 0.0709 1
Leishmania major cathepsin L-like protease 0.009 0.0475 0.0805
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0109 0.0592 0.833
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0178 0.1011 0.1525
Schistosoma mansoni topbp1 0.0014 0.0011 0.0015
Plasmodium falciparum thioredoxin reductase 0.0034 0.0131 0.0213
Echinococcus multilocularis sterol regulatory element binding protein 0.0032 0.0117 0.0115
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi photoreceptor-specific nuclear receptor 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus granulosus G protein coupled receptor 139 0.0178 0.1011 0.1525
Onchocerca volvulus 0.0016 0.002 0.0177
Loa Loa (eye worm) latrophilin receptor protein 2 0.0046 0.0204 0.0364
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0044 0.0195 0.0292
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.1011 0.1525
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0034 0.0133 0.0217
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0046 0.0204 0.0203
Loa Loa (eye worm) hypothetical protein 0.0023 0.0064 0.0114
Echinococcus multilocularis lamin 0.0023 0.0067 0.0065
Trypanosoma brucei trypanothione reductase 0.0034 0.0131 0.0213
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0038 0.0154 0.2449
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0013 0.0002 0.0001
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0013 0.0002 0.0001
Echinococcus granulosus cathepsin l cysteine peptidase 0.0024 0.0068 0.0101
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0044 0.0195 0.0292
Brugia malayi Probable ClpP-like protease 0.0109 0.0592 0.1057
Echinococcus granulosus cathepsin L cysteine proteinase 0.0024 0.0068 0.0101
Echinococcus multilocularis Niemann Pick C1 protein 0.0105 0.0568 0.0567
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0053 0.0075
Brugia malayi Cathepsin L-like precursor 0.0024 0.0068 0.0121
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0082 0.0427 0.0742
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0178 0.1011 0.1804
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.1011 0.101
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0086 0.0449 0.7534
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0013 0.0002 0.0004
Brugia malayi Cathepsin L-like cysteine proteinase 0.0016 0.002 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.008 0.0411 0.5732
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0032 0.0121 0.012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0013 0.0002 0.0001
Toxoplasma gondii melibiase subfamily protein 0.0067 0.033 0.057
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0067 0.033 0.0329
Onchocerca volvulus 0.0178 0.1011 1
Echinococcus granulosus dna polymerase eta 0.0026 0.0081 0.012
Echinococcus multilocularis thyroid hormone receptor alpha 0.0013 0.0002 0.0001
Plasmodium falciparum glutathione reductase 0.0034 0.0131 0.0213
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0244 0.1415 0.2509
Loa Loa (eye worm) hypothetical protein 0.0116 0.063 0.1124
Brugia malayi beta-lactamase family protein 0.0076 0.0391 0.0697
Brugia malayi hypothetical protein 0.0346 0.2038 0.3636
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0178 0.1011 0.1525
Brugia malayi Dopamine receptor 0.0178 0.1011 0.1804
Trichomonas vaginalis ran, putative 0.002 0.0046 0.0061
Brugia malayi Dopamine receptor protein 1 0.0178 0.1011 0.1804
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0013 0.0002 0.0004
Schistosoma mansoni myosin xvIII 0.0178 0.1011 0.1525
Schistosoma mansoni retinoic acid receptor RXR 0.0013 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0204 0.0364
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0017 0.0026 0.0026
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0092 0.0164
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0028 0.0093 0.0166
Trypanosoma cruzi PAB1-binding protein , putative 0.0018 0.0032 0.0038
Loa Loa (eye worm) MH2 domain-containing protein 0.0078 0.0398 0.071
Schistosoma mansoni hypothetical protein 0.0178 0.1011 0.1525
Leishmania major DNA polymerase eta, putative 0.0026 0.0081 0.0098
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.008 0.0411 0.1336
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus granulosus expressed conserved protein 0.0069 0.0347 0.0522
Brugia malayi beta-lactamase 0.0076 0.0391 0.0697
Schistosoma mansoni chromosome transmission fidelity factor 0.0014 0.0011 0.0015
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0929 0.5607 1
Echinococcus granulosus allatostatin A receptor 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0032 0.0121 0.0181
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0929 0.5607 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0178 0.1011 0.1525
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0024 0.0068 0.0101
Loa Loa (eye worm) hypothetical protein 0.0026 0.0081 0.0144
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0028 0.0093 0.0166
Echinococcus granulosus ubiquitin specific protease 41 0.0021 0.0053 0.0078
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0391 0.0678
Loa Loa (eye worm) hypothetical protein 0.0099 0.0531 0.0946
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0115 0.0629 0.1081
Echinococcus multilocularis protein tyrosine kinase 0.0179 0.1019 0.1018
Mycobacterium tuberculosis Conserved protein 0.0076 0.0391 0.1265
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0068 0.0101
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0059 0.0285 0.049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0068 0.0101
Loa Loa (eye worm) hypothetical protein 0.0076 0.0391 0.0697
Echinococcus granulosus snurportin 1 0.029 0.17 0.2564
Echinococcus multilocularis cysteine protease 0.0024 0.0068 0.0067
Echinococcus multilocularis neuropeptide receptor A26 0.0483 0.2881 0.288
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0032 0.0121 0.012
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0024 0.0068 0.0101
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus granulosus neuropeptide s receptor 0.0483 0.2881 0.4347
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0178 0.1011 0.101
Schistosoma mansoni opsin-like receptor 0.0178 0.1011 0.1525
Trichomonas vaginalis esterase, putative 0.0076 0.0391 0.0678
Schistosoma mansoni hypothetical protein 0.0178 0.1011 0.1525
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi latrophilin 2 splice variant baaae 0.0099 0.0531 0.0946
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0059 0.0285 0.0509
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0086 0.0449 0.1467
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.002 0.0046 0.0081
Brugia malayi CHE-14 protein 0.0032 0.0117 0.0208
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0013 0.0002 0.0001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0145 0.0812 0.1448
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.0391 0.5441
Schistosoma mansoni hypothetical protein 0.0046 0.0204 0.0307
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0109 0.0592 0.0893
Echinococcus granulosus Niemann Pick C1 protein 0.0105 0.0568 0.0856
Echinococcus multilocularis importin subunit beta 1 0.0027 0.0089 0.0088
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0013 0.0002 0.0001
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0929 0.5607 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus granulosus aryl hydrocarbon receptor 0.004 0.0165 0.0248
Brugia malayi nuclear hormone receptor 0.0013 0.0002 0.0004
Echinococcus granulosus neuropeptide FF receptor 2 0.0178 0.1011 0.1525
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0046 0.0204 0.0203
Brugia malayi Bromodomain containing protein 0.0056 0.0267 0.0476
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0021 0.0053 0.0078
Plasmodium falciparum ataxin-2 like protein, putative 0.0018 0.0032 0.0038
Echinococcus multilocularis musashi 0.0023 0.0067 0.0065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0068 0.0101
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0077 0.0396 0.6625
Entamoeba histolytica hypothetical protein 0.0051 0.0234 0.0398
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Brugia malayi Melibiase family protein 0.0044 0.0195 0.0347
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.1011 0.1525
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0089 0.014
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0025 0.0073 0.011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus granulosus g protein coupled receptor 0.0178 0.1011 0.1525
Echinococcus granulosus 7TM GPCR rhodopsin 0.0178 0.1011 0.1525
Trypanosoma cruzi DNA polymerase eta, putative 0.0026 0.0081 0.0124
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0013 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0443 0.2631 0.397
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0024 0.0068 0.0121
Onchocerca volvulus 0.0014 0.0011 0.0092
Brugia malayi Dopamine receptor protein 2 0.0178 0.1011 0.1804
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0391 0.0588
Echinococcus multilocularis thioredoxin glutathione reductase 0.0034 0.0131 0.0129
Echinococcus multilocularis cysteine protease 0.0024 0.0068 0.0067
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0072 0.0362 0.1165
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0053 0.0049
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0025 0.0073 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0053 0.0075
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0209 0.1199 0.2138
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0053 0.0075
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0022 0.0057 0.0792
Loa Loa (eye worm) hypothetical protein 0.0346 0.2038 0.3636
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0032 0.0121 0.0181
Schistosoma mansoni histamine h1 receptor 0.0178 0.1011 0.1525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0178 0.1011 0.101
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.0391 0.1265
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0075 0.0382 0.0681
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0017 0.0026 0.0205
Brugia malayi hypothetical protein 0.0014 0.0011 0.002
Toxoplasma gondii cathepsin CPL 0.0024 0.0068 0.0101
Echinococcus granulosus tm gpcr rhodopsin 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0028 0.0092 0.0164
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0115 0.0629 0.1104
Onchocerca volvulus 0.0178 0.1011 1
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0067 0.033 0.0497
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0002 0.0001
Brugia malayi larval opioid receptor 0.0178 0.1011 0.1804
Echinococcus multilocularis neuropeptide s receptor 0.0483 0.2881 0.288
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0178 0.1011 0.1525
Echinococcus multilocularis zinc finger protein 0.0015 0.0013 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.1011 0.101
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0109 0.0592 0.0591
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0929 0.5607 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.002 0.0046 0.0061
Brugia malayi hypothetical protein 0.0178 0.1011 0.1804
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0109 0.0592 0.1039
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.1011 0.1525
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Entamoeba histolytica Ran family GTPase 0.002 0.0046 0.0061
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0178 0.1011 0.1525
Brugia malayi beta-lactamase family protein 0.0076 0.0391 0.0697
Schistosoma mansoni amine GPCR 0.0178 0.1011 0.1525
Brugia malayi sulfakinin receptor protein 0.0178 0.1011 0.1804
Schistosoma mansoni amine GPCR 0.0178 0.1011 0.1525
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0068 0.0101
Leishmania major importin beta-1 subunit, putative 0.0022 0.0058 0.0058
Leishmania major mitochondrial DNA polymerase beta 0.0244 0.1415 0.249
Echinococcus multilocularis neuropeptides capa receptor 0.0178 0.1011 0.101
Echinococcus granulosus intermediate filament protein 0.0023 0.0067 0.0099
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.076 0.1338
Onchocerca volvulus 0.0178 0.1011 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0178 0.1011 0.101
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0013 0.0002 0.0001
Loa Loa (eye worm) TYRA-2 protein 0.0178 0.1011 0.1804
Schistosoma mansoni inositol monophosphatase 0.0025 0.0073 0.0109
Onchocerca volvulus 0.0178 0.1011 1
Echinococcus granulosus serotonin receptor 0.0178 0.1011 0.1525
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0178 0.1011 0.1804
Schistosoma mansoni amine GPCR 0.0178 0.1011 0.1525
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0034 0.0133 0.0217
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Echinococcus granulosus lamin 0.0023 0.0067 0.0099
Schistosoma mansoni steroid hormone receptor ad4bp 0.0013 0.0002 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus granulosus alpha 1A adrenergic receptor 0.0178 0.1011 0.1525
Trypanosoma cruzi importin beta-1 subunit, putative 0.0022 0.0058 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.1011 0.101
Brugia malayi ImpB/MucB/SamB family protein 0.0026 0.0081 0.0144
Schistosoma mansoni biogenic amine (5HT) receptor 0.0178 0.1011 0.1525
Echinococcus multilocularis protein patched 0.0032 0.0117 0.0115
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0178 0.1011 0.1525
Echinococcus multilocularis aryl hydrocarbon receptor 0.004 0.0165 0.0164
Trichomonas vaginalis glucosylceramidase, putative 0.0144 0.0805 0.1419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Trichomonas vaginalis inositol monophosphatase, putative 0.0025 0.0073 0.011
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0021 0.0053 0.0078
Trypanosoma cruzi PAB1-binding protein , putative 0.0018 0.0032 0.0038
Loa Loa (eye worm) hypothetical protein 0.0178 0.1011 0.1804
Brugia malayi Cathepsin L-like precursor 0.0024 0.0068 0.0121
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.076 0.1338
Schistosoma mansoni growth hormone secretagogue receptor 0.0178 0.1011 0.1525
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0013 0.0002 0.0004
Brugia malayi putative neuropeptide receptor 0.0178 0.1011 0.1804
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0929 0.5607 1
Echinococcus multilocularis serotonin receptor 0.0178 0.1011 0.101
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0391 0.0678
Loa Loa (eye worm) cysteine protease 0.0024 0.0068 0.0121
Echinococcus multilocularis GPCR, family 2 0.0046 0.0204 0.0203
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0072 0.0362 0.6031
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0014 0.0011 0.00000061743
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0178 0.1011 0.1525
Mycobacterium tuberculosis Probable dehydrogenase 0.0077 0.0396 0.1284
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus granulosus lamin dm0 0.0023 0.0067 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.0391 0.0697
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0032 0.0121 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0475 0.0828
Echinococcus granulosus fetal alzheimer antigen falz 0.0017 0.0026 0.0038
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0051 0.0234 0.0233
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0929 0.5607 1
Leishmania major cathepsin L-like protease 0.0024 0.0068 0.0076
Echinococcus multilocularis g protein coupled receptor 0.0178 0.1011 0.101
Echinococcus multilocularis FTZ F1 alpha 0.0013 0.0002 0.0001
Brugia malayi Latrophilin receptor protein 2 0.0046 0.0204 0.0364
Schistosoma mansoni topbp1 0.0014 0.0011 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0068 0.0101
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0021 0.0053 0.0052
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0002 0.0004
Echinococcus multilocularis lamin dm0 0.0023 0.0067 0.0065
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0038 0.0154 0.0254
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.1011 0.1525
Echinococcus granulosus protein tyrosine kinase 0.0179 0.1019 0.1537
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.1011 0.101
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0013 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0119 0.0211
Loa Loa (eye worm) neuropeptide F receptor 0.0178 0.1011 0.1804
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0189 0.0283
Loa Loa (eye worm) hypothetical protein 0.0076 0.0391 0.0697
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0024 0.0068 0.0101
Mycobacterium tuberculosis Conserved protein 0.0076 0.0391 0.1265
Leishmania major cathepsin L-like protease 0.009 0.0475 0.0805
Brugia malayi Cathepsin L-like precursor 0.0016 0.002 0.0036
Echinococcus multilocularis fmrfamide receptor 0.0178 0.1011 0.101
Toxoplasma gondii aldehyde dehydrogenase 0.008 0.0411 0.0715
Schistosoma mansoni hypothetical protein 0.0046 0.0204 0.0307
Loa Loa (eye worm) hypothetical protein 0.0044 0.0195 0.0347
Brugia malayi ecdysteroid receptor 0.0013 0.0002 0.0004
Loa Loa (eye worm) G-protein coupled receptor 0.0178 0.1011 0.1804
Echinococcus multilocularis nibrin 0.0014 0.0011 0.001
Echinococcus granulosus GPCR family 2 0.0046 0.0204 0.0307
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.076 0.1338

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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