Detailed information for compound 201677

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 321.294 | Formula: C17H14F3NO2
  • H donors: 1 H acceptors: 2 LogP: 3.79 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccccc1)CCc1ccc(cc1)C(=O)C(F)(F)F
  • InChi: 1S/C17H14F3NO2/c18-17(19,20)16(23)13-9-6-12(7-10-13)8-11-15(22)21-14-4-2-1-3-5-14/h1-7,9-10H,8,11H2,(H,21,22)
  • InChiKey: LFAPZYSBVAVANK-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0602 0.1055
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0075 0.0332 0.1535
Onchocerca volvulus 0.0067 0.028 0.0273
Mycobacterium tuberculosis Probable reductase 0.0196 0.1104 0.4193
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0041 0.0015
Onchocerca volvulus Cathepsin L homolog 0.0297 0.1749 0.3013
Brugia malayi Cathepsin L-like precursor 0.0207 0.1174 0.213
Schistosoma mansoni alpha-glucosidase 0.0113 0.0571 0.0766
Toxoplasma gondii preprocathepsin c precursor, putative 0.0075 0.0332 0.1705
Echinococcus granulosus transmembrane protease serine 3 0.0052 0.0181 0.022
Brugia malayi Papain family cysteine protease containing protein 0.0075 0.0332 0.0602
Mycobacterium tuberculosis Conserved protein 0.0067 0.0277 0.0932
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0045 0.0139 0.0388
Giardia lamblia Cathepsin L precursor 0.0075 0.0332 0.1535
Brugia malayi TAR-binding protein 0.0051 0.0176 0.0319
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0181 0.022
Onchocerca volvulus 0.0297 0.1749 0.3013
Echinococcus granulosus cathepsin l cysteine peptidase 0.0297 0.1749 0.2414
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0069 0.0291 1
Echinococcus granulosus calpain 5 0.0041 0.0111 0.0122
Schistosoma mansoni hypothetical protein 0.0165 0.0904 0.1233
Plasmodium falciparum cysteine proteinase falcipain 1 0.0165 0.0906 0.5175
Schistosoma mansoni cathepsin s 0.009 0.0425 0.0562
Giardia lamblia Cathepsin B precursor 0.0075 0.0332 0.1535
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Echinococcus granulosus cathepsin l1 0.0297 0.1749 0.2414
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0075 0.0332 0.0431
Brugia malayi Kringle domain containing protein 0.0058 0.0219 0.0397
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0243 0.8059
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0176 0.0213
Loa Loa (eye worm) hypothetical protein 0.0207 0.1174 0.2097
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0906 0.509
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0075 0.0332 0.0431
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0069 0.0291 0.0374
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0906 0.509
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.1749 0.3139
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0041 0.0015
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0058 0.0219 0.1239
Onchocerca volvulus 0.0297 0.1749 0.3013
Brugia malayi Trypsin family protein 0.0052 0.0181 0.0328
Loa Loa (eye worm) fibroinase 0.0297 0.1749 0.3144
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0034 0.0068 0.1063
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.003 0.0044 0.0028
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0127 0.0664 0.0896
Brugia malayi Cathepsin L-like precursor 0.0297 0.1749 0.3173
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0034 0.0068 0.1063
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0075 0.0332 0.1885
Brugia malayi Trypsin family protein 0.0052 0.0181 0.0328
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0111 0.0562 0.2896
Onchocerca volvulus 0.0297 0.1749 0.3013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.0332 0.0541
Brugia malayi Importin beta-1 subunit 0.0027 0.0024 0.0043
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0165 0.0904 0.1232
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0075 0.0332 0.1885
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0152 0.0824 0.112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Brugia malayi Cathepsin L-like precursor 0.0297 0.1749 0.3173
Schistosoma mansoni hypothetical protein 0.0156 0.0846 0.1151
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0243 0.8059
Echinococcus granulosus calpain 0.0041 0.0111 0.0122
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0152 0.0824 0.4191
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0069 0.0291 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0165 0.0904 0.0882
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0326 0.1934 0.3477
Loa Loa (eye worm) papain family cysteine protease containing protein 0.009 0.0425 0.0732
Mycobacterium tuberculosis Probable hydrolase 0.0067 0.0277 0.0932
Loa Loa (eye worm) hypothetical protein 0.0165 0.0904 0.1605
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0243 0.8059
Echinococcus granulosus calpain A 0.0113 0.0572 0.0767
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0075 0.0332 0.1885
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0297 0.1749 1
Echinococcus multilocularis cysteine protease 0.0297 0.1749 0.173
Schistosoma mansoni transcription factor LCR-F1 0.003 0.0044 0.0028
Loa Loa (eye worm) hypothetical protein 0.0069 0.0291 0.0487
Brugia malayi Cathepsin L-like precursor 0.0297 0.1749 0.3173
Brugia malayi beta-lactamase 0.0067 0.0277 0.0503
Trypanosoma cruzi cysteine peptidase, putative 0.0297 0.1749 0.3132
Trichomonas vaginalis inositol monophosphatase, putative 0.0034 0.0068 0.0057
Brugia malayi Trypsin-like protease protein 5 0.0052 0.0181 0.0328
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0075 0.0332 0.0561
Mycobacterium tuberculosis Conserved protein 0.0067 0.0277 0.0932
Schistosoma mansoni hypothetical protein 0.0165 0.0904 0.1233
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.003 0.0045 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0075 0.0332 0.0541
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0069 0.0291 0.1653
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Echinococcus multilocularis tissue type plasminogen activator 0.0058 0.0219 0.0196
Echinococcus multilocularis cathepsin b 0.0887 0.5512 0.5502
Brugia malayi beta-lactamase family protein 0.0067 0.0277 0.0503
Plasmodium falciparum serine repeat antigen 1 0.0075 0.0332 0.1885
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0243 0.022
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0152 0.0824 0.112
Mycobacterium ulcerans hypothetical protein 0.0052 0.0181 0.5586
Schistosoma mansoni cathepsin F (C01 family) 0.0297 0.1749 0.2414
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0113 0.0572 0.0767
Trypanosoma cruzi cysteine peptidase, putative 0.009 0.0425 0.0716
Schistosoma mansoni hypothetical protein 0.0289 0.1696 0.2339
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.1749 0.3139
Brugia malayi beta-lactamase family protein 0.0067 0.0277 0.0503
Echinococcus granulosus SAM and MBT domain containing protein 0.0044 0.0134 0.0155
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0165 0.0904 0.0883
Loa Loa (eye worm) MBCTL1 0.0051 0.0173 0.0273
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0243 0.0306
Brugia malayi hypothetical protein 0.003 0.0044 0.0079
Echinococcus multilocularis cysteine protease 0.0297 0.1749 0.173
Loa Loa (eye worm) hypothetical protein 0.0207 0.1174 0.2097
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0176 0.0213
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0152 0.0824 0.309
Loa Loa (eye worm) hypothetical protein 0.0522 0.3181 0.5752
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0067 0.0277 0.0503
Echinococcus granulosus cathepsin L 0.0165 0.0906 0.1235
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0041 0.0074
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0069 0.0291 0.2326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0075 0.0332 0.1885
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0075 0.0332 0.1885
Brugia malayi hypothetical protein 0.0052 0.0181 0.0328
Leishmania major trypanothione reductase 0.0086 0.04 0.1932
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.1749 0.3139
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0052 0.0181 0.022
Onchocerca volvulus 0.0052 0.0181 0.0087
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Entamoeba histolytica cysteine protease, putative 0.0075 0.0332 0.1742
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0111 0.0143
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0041 0.0025
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0196 0.1104 0.4193
Loa Loa (eye worm) hypothetical protein 0.0052 0.0181 0.0286
Loa Loa (eye worm) TK/ROR protein kinase 0.0058 0.0219 0.0356
Echinococcus multilocularis calpain 7 (C02 family) 0.0041 0.0111 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Echinococcus granulosus cathepsin L cysteine proteinase 0.0297 0.1749 0.2414
Brugia malayi Pre-SET motif family protein 0.0777 0.4808 0.8723
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Echinococcus granulosus cathepsin L cysteine protease 0.0165 0.0906 0.1235
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0075 0.0332 0.1885
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0165 0.0906 0.4621
Plasmodium falciparum glutathione reductase 0.003 0.0041 0.0221
Mycobacterium tuberculosis Probable oxidoreductase 0.0218 0.1243 0.4745
Loa Loa (eye worm) hypothetical protein 0.009 0.0425 0.0732
Plasmodium vivax calpain, putative 0.0041 0.0111 0.0621
Schistosoma mansoni myelin transcription factor 1 myt1 0.0051 0.0173 0.0209
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0036 0.0007
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0297 0.1749 0.173
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0075 0.0332 0.1885
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0041 0.0092
Giardia lamblia Cathepsin B precursor 0.0075 0.0332 0.1535
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0068 0.0057
Echinococcus multilocularis snurportin 1 0.0289 0.1696 0.1676
Echinococcus multilocularis beta LACTamase domain containing family member 0.0067 0.0277 0.0254
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0041 0.0009
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0108 0.0541 0.0723
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0152 0.0824 0.1444
Trypanosoma brucei antigen, putative 0.0041 0.0111 0.0458
Trypanosoma cruzi cruzipain precursor, putative 0.0297 0.1749 0.3132
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0165 0.0906 0.1235
Trypanosoma brucei trypanothione reductase 0.0086 0.04 0.197
Loa Loa (eye worm) hypothetical protein 0.0044 0.0134 0.0201
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0041 0.0111 0.0143
Echinococcus multilocularis cathepsin b 0.0887 0.5512 0.5502
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Loa Loa (eye worm) hypothetical protein 0.0067 0.0277 0.0462
Schistosoma mansoni alpha glucosidase 0.0029 0.0036 0.0018
Onchocerca volvulus 0.0297 0.1749 0.3013
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Mycobacterium ulcerans beta-lactamase 0.0067 0.0277 0.9443
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.1749 0.3139
Brugia malayi Cathepsin L-like precursor 0.0297 0.1749 0.3173
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0748 0.1014
Plasmodium vivax vivapain-1 0.0165 0.0906 0.5175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Brugia malayi cathepsin Z-like cysteine proteinase 0.0075 0.0332 0.0602
Echinococcus multilocularis cathepsin L cysteine protease 0.0297 0.1749 0.173
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0887 0.5512 0.768
Brugia malayi Papain family cysteine protease containing protein 0.0075 0.0332 0.0602
Mycobacterium leprae conserved hypothetical protein 0.0067 0.0277 0.2214
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0075 0.0332 0.1885
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0326 0.1934 1
Schistosoma mansoni alpha-glucosidase 0.0113 0.0571 0.0766
Trypanosoma cruzi cysteine proteinase, putative 0.0165 0.0906 0.1594
Trichomonas vaginalis set domain proteins, putative 0.0884 0.5493 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0277 0.0462
Plasmodium vivax importin-beta 2, putative 0.0027 0.0024 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.0332 0.0541
Loa Loa (eye worm) hypothetical protein 0.0297 0.1749 0.3144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0067 0.0277 0.0355
Loa Loa (eye worm) hypothetical protein 0.0207 0.1174 0.2097
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0522 0.3181 0.5752
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0075 0.0332 0.1885
Plasmodium vivax glutathione reductase, putative 0.0086 0.04 0.2276
Trypanosoma brucei cysteine peptidase C (CPC) 0.0326 0.1934 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0111 0.0143
Loa Loa (eye worm) hypothetical protein 0.0127 0.0664 0.1167
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0165 0.0904 0.0883
Leishmania major cathepsin L-like protease 0.0297 0.1749 0.9027
Echinococcus granulosus thioredoxin glutathione reductase 0.0087 0.0403 0.0531
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0041 0.0044
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0068 0.0231
Echinococcus granulosus tissue type plasminogen activator 0.0058 0.0219 0.0273
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0887 0.5512 0.768
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0075 0.0332 0.0602
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0289 0.1696 0.3046
Plasmodium falciparum eukaryotic initiation factor 4A 0.0152 0.0824 0.4704
Loa Loa (eye worm) DEAH box polypeptide 35 0.038 0.2274 0.41
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Plasmodium vivax serine-repeat antigen (SERA) 0.0075 0.0332 0.1885
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0151
Brugia malayi Latrophilin receptor protein 2 0.0165 0.0904 0.1641
Leishmania major cathepsin L-like protease 0.0297 0.1749 0.9027
Onchocerca volvulus 0.0884 0.5493 1
Echinococcus granulosus lysosomal alpha glucosidase 0.0131 0.0687 0.0928
Echinococcus multilocularis transmembrane protease serine 3 0.0052 0.0181 0.0158
Giardia lamblia Cathepsin B precursor 0.0326 0.1934 1
Loa Loa (eye worm) hypothetical protein 0.009 0.0425 0.0732
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0069 0.0291 1
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.0024 0.0109
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0075 0.0332 0.0431
Onchocerca volvulus 0.0207 0.1174 0.1941
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0243 0.0306
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0175 0.0967 0.132
Loa Loa (eye worm) hypothetical protein 0.0075 0.0332 0.0561
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.1749 0.3139
Plasmodium vivax RNA helicase-1, putative 0.0152 0.0824 0.4704
Echinococcus granulosus peptidase Clp S14 family 0.0045 0.0139 0.0162
Loa Loa (eye worm) thioredoxin reductase 0.0086 0.04 0.0686
Onchocerca volvulus 0.0089 0.0418 0.0531
Loa Loa (eye worm) hypothetical protein 0.0067 0.0277 0.0462
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0111 0.0143
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0111 0.0458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0165 0.0906 0.1235
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0069 0.0291 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0297 0.1749 0.3144
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0075 0.0332 0.0541
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0041 0.0015
Brugia malayi Cathepsin L-like precursor 0.0207 0.1174 0.213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0165 0.0906 0.1594
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0075 0.0332 0.1535
Brugia malayi calpain 7 0.0041 0.0111 0.0201
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0152 0.0824 0.1444
Toxoplasma gondii cathepsin B 0.0326 0.1934 1
Giardia lamblia Cathepsin L precursor 0.0075 0.0332 0.1535
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0041 0.0092
Schistosoma mansoni hypothetical protein 0.0357 0.2127 0.2943
Plasmodium vivax vivapain-2 0.0297 0.1749 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0069 0.0291 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0165 0.0906 0.1594
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0075 0.0332 0.0431
Giardia lamblia Cathepsin B precursor 0.0075 0.0332 0.1535
Brugia malayi mbt repeat family protein 0.0044 0.0134 0.0243
Loa Loa (eye worm) calpain family protein 1 0.0108 0.0541 0.0942
Brugia malayi Papain family cysteine protease containing protein 0.0297 0.1749 0.3173
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0034 0.0068 0.0337
Loa Loa (eye worm) cathepsin B 0.0326 0.1934 0.3481
Trypanosoma cruzi cysteine peptidase, putative 0.0297 0.1749 0.3132
Entamoeba histolytica hypothetical protein 0.003 0.0044 0.0064
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0075 0.0332 0.1885
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Plasmodium falciparum serine repeat antigen 6 0.0075 0.0332 0.1885
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0277 0.0441
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0051 0.0176 0.0278
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0069 0.0291 0.1494
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0152 0.0824 0.4254
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0075 0.0332 0.0541
Entamoeba histolytica cysteine protease, putative 0.0075 0.0332 0.1742
Loa Loa (eye worm) hypothetical protein 0.0067 0.0277 0.0462
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0044 0.0134 0.0155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0165 0.0904 0.0882
Trypanosoma cruzi cysteine peptidase, putative 0.0165 0.0906 0.1594
Toxoplasma gondii cathepsin CPL 0.0297 0.1749 0.9042
Echinococcus multilocularis inositol monophosphatase 1 0.0034 0.0068 0.0044
Loa Loa (eye worm) TAR-binding protein 0.0051 0.0176 0.0278
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0041 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Giardia lamblia Encystation-specific protease 0.0075 0.0332 0.1535
Echinococcus granulosus neutral alpha glucosidase AB 0.0029 0.0036 0.0018
Loa Loa (eye worm) hypothetical protein 0.0067 0.0277 0.0462
Onchocerca volvulus 0.0076 0.0334 0.0374
Loa Loa (eye worm) mbt repeat family protein 0.0044 0.0134 0.0201
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0111 0.0143
Echinococcus granulosus cathepsin b 0.0887 0.5512 0.768
Trypanosoma brucei kinesin, putative 0.0029 0.0033 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.0332 0.0541
Giardia lamblia Cathepsin L precursor 0.0075 0.0332 0.1535
Brugia malayi eukaryotic initiation factor 4A 0.0152 0.0824 0.1495
Mycobacterium leprae Probable lipase LipE 0.0067 0.0277 0.2214
Trypanosoma brucei glucosidase, putative 0.0029 0.0036 0.0067
Loa Loa (eye worm) hypothetical protein 0.0066 0.0275 0.0457
Brugia malayi glutathione reductase 0.0086 0.04 0.0726
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0277 0.0446
Echinococcus multilocularis peptidase Clp (S14 family) 0.0045 0.0139 0.0116
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0243 0.0306
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0602 0.1055
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0069 0.0291 0.0268
Entamoeba histolytica cysteine proteinase 2 0.0165 0.0906 0.509
Loa Loa (eye worm) hypothetical protein 0.0096 0.0462 0.08
Toxoplasma gondii kringle domain-containing protein 0.0058 0.0219 0.112
Toxoplasma gondii thioredoxin reductase 0.0086 0.04 0.2058
Echinococcus multilocularis calpain 5 0.0041 0.0111 0.0088
Schistosoma mansoni hypothetical protein 0.027 0.1573 0.2168
Entamoeba histolytica cysteine protease, putative 0.0297 0.1749 1
Trypanosoma cruzi cysteine peptidase, putative 0.0297 0.1749 0.3132
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0111 0.0458
Plasmodium vivax unspecified product 0.0075 0.0332 0.1885
Loa Loa (eye worm) hypothetical protein 0.0075 0.0332 0.0561
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0075 0.0332 0.0541
Brugia malayi Cathepsin L-like precursor 0.009 0.0425 0.0772
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Echinococcus multilocularis neutral alpha glucosidase AB 0.0029 0.0036 0.0013
Onchocerca volvulus Cathepsin L homolog 0.0297 0.1749 0.3013
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.0036 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0887 0.5512 1
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0075 0.0332 0.0561
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0165 0.0906 0.1235
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0041 0.0015
Brugia malayi cathepsin Z-like cysteine proteinase 0.0075 0.0332 0.0602
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0067 0.0277 0.0932
Toxoplasma gondii cathepsin CPC1 0.0075 0.0332 0.1705
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0052 0.0181 0.0158
Giardia lamblia Cathepsin B precursor 0.0075 0.0332 0.1535
Onchocerca volvulus 0.0067 0.0277 0.0267
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0029 0.0036 0.0175
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0111 0.0143
Leishmania major cathepsin L-like protease 0.0297 0.1749 0.9027
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0113 0.0572 0.0767
Brugia malayi calpain 5 0.0029 0.0033 0.0059
Entamoeba histolytica hypothetical protein 0.003 0.0044 0.0064
Echinococcus multilocularis Mastin 0.0052 0.0181 0.0158
Toxoplasma gondii cathepsin CPC2 0.0075 0.0332 0.1705
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0906 0.509
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Plasmodium falciparum serine repeat antigen 8 0.0075 0.0332 0.1885
Echinococcus granulosus calpain A 0.0041 0.0111 0.0122
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0041 0.0221
Brugia malayi cathepsin L-like precursor 0.0207 0.1174 0.213
Echinococcus granulosus cathepsin l1 0.0207 0.1174 0.161
Schistosoma mansoni Mername-AA248 (C02 family) 0.0041 0.0111 0.0122
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0152 0.0824 0.1288
Plasmodium falciparum serine repeat antigen 4 0.0075 0.0332 0.1885
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0075 0.0332 0.0431
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0075 0.0332 0.0541
Giardia lamblia Cysteine protease 0.0075 0.0332 0.1535
Brugia malayi calpain family protein 1 0.0108 0.0541 0.0981
Giardia lamblia Cysteine protease 0.0075 0.0332 0.1535
Schistosoma mansoni hypothetical protein 0.0052 0.0181 0.022
Entamoeba histolytica cysteine proteinase, putative 0.0297 0.1749 1
Giardia lamblia Cysteine protease 0.0075 0.0332 0.1535
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0075 0.0332 0.0541
Loa Loa (eye worm) hypothetical protein 0.038 0.2274 0.41
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0041 0.0015
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0152 0.0824 0.4611
Brugia malayi Cathepsin L-like cysteine proteinase 0.0207 0.1174 0.213
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0111 0.0411
Giardia lamblia Cathepsin L precursor 0.0075 0.0332 0.1535
Trypanosoma brucei hypothetical protein, conserved 0.0067 0.0277 0.1328
Brugia malayi hypothetical protein 0.0231 0.1322 0.2399
Treponema pallidum NADH oxidase 0.003 0.0041 0.047
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0152 0.0824 0.0802
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0075 0.0332 0.1885
Onchocerca volvulus 0.0067 0.0277 0.0267
Entamoeba histolytica cysteine protease, putative 0.0075 0.0332 0.1742
Echinococcus multilocularis microtubule associated protein 2 0.1147 0.7171 0.7164
Brugia malayi Pre-SET motif family protein 0.0111 0.0562 0.1019
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Loa Loa (eye worm) hypothetical protein 0.0051 0.0173 0.0273
Echinococcus multilocularis cathepsin L 0.0165 0.0906 0.0885
Echinococcus granulosus microtubule associated protein 2 0.1147 0.7171 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0165 0.0904 0.1232
Schistosoma mansoni cathepsin B (C01 family) 0.0075 0.0332 0.0431
Echinococcus granulosus calpain 7 C02 family 0.0041 0.0111 0.0122
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0034 0.0068 0.0203
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0152 0.0824 0.112
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0111 0.0143
Echinococcus multilocularis enteropeptidase 0.0052 0.0181 0.0158
Onchocerca volvulus 0.0067 0.0277 0.0267
Entamoeba histolytica cysteine protease, putative 0.0075 0.0332 0.1742
Brugia malayi latrophilin 2 splice variant baaae 0.0357 0.2127 0.3859
Plasmodium vivax unspecified product 0.0165 0.0906 0.5175
Brugia malayi Calcitonin receptor-like protein seb-1 0.0522 0.3181 0.5771
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0111 0.0143
Brugia malayi Bromodomain containing protein 0.0036 0.008 0.0146
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0218 0.1243 1
Echinococcus granulosus glycoprotein Antigen 5 0.0052 0.0181 0.022
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0041 0.0111 0.0458
Onchocerca volvulus 0.0297 0.1749 0.3013
Mycobacterium tuberculosis Probable lipase LipD 0.0067 0.0277 0.0932
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0052 0.0181 0.0328
Schistosoma mansoni inositol monophosphatase 0.0034 0.0068 0.0062
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0041 0.0018
Loa Loa (eye worm) hypothetical protein 0.0141 0.0748 0.1321
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Giardia lamblia Cathepsin B precursor 0.0326 0.1934 1
Entamoeba histolytica hypothetical protein 0.003 0.0044 0.0064
Entamoeba histolytica cysteine proteinase, putative 0.0297 0.1749 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0104
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0045 0.0139 0.0388
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.1749 0.3139
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0297 0.1749 0.173
Schistosoma mansoni cathepsin F (C01 family) 0.0297 0.1749 0.2414
Onchocerca volvulus 0.0297 0.1749 0.3013
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0297 0.1749 1
Giardia lamblia Cysteine protease 0.0075 0.0332 0.1535
Loa Loa (eye worm) hypothetical protein 0.0052 0.0181 0.0286
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0067 0.0277 0.0462
Entamoeba histolytica cysteine protease, putative 0.0075 0.0332 0.1742
Loa Loa (eye worm) hypothetical protein 0.0108 0.0541 0.0942
Trichomonas vaginalis esterase, putative 0.0067 0.0277 0.0441
Trypanosoma cruzi cysteine peptidase, putative 0.0297 0.1749 0.3132
Plasmodium falciparum importin beta, putative 0.0027 0.0024 0.0121
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0181 0.0158
Onchocerca volvulus 0.0058 0.0219 0.0158
Plasmodium falciparum serine repeat antigen 7 0.0075 0.0332 0.1885
Brugia malayi Glycosyl hydrolases family 31 protein 0.0131 0.0687 0.1246
Loa Loa (eye worm) latrophilin receptor protein 2 0.0165 0.0904 0.1605
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0127 0.0664 0.0642
Echinococcus granulosus cysteine protease 0.0165 0.0906 0.1235
Loa Loa (eye worm) hypothetical protein 0.0075 0.0332 0.0561
Schistosoma mansoni calpain (C02 family) 0.0041 0.0111 0.0122
Echinococcus granulosus inositol monophosphatase 1 0.0034 0.0068 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Onchocerca volvulus 0.0141 0.0748 0.1146
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0075 0.0332 0.0541
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0068 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0297 0.1749 0.3139
Loa Loa (eye worm) hypothetical protein 0.0075 0.0332 0.0561
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0277 0.0441
Echinococcus multilocularis tar DNA binding protein 0.0051 0.0176 0.0153
Mycobacterium ulcerans esterase/lipase LipP 0.0067 0.0277 0.9443
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0887 0.5512 0.768
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0326 0.1934 0.347
Onchocerca volvulus Cathepsin F homolog 0.0297 0.1749 0.3013
Mycobacterium tuberculosis Probable dehydrogenase 0.0196 0.1104 0.4193
Echinococcus multilocularis lysosomal alpha glucosidase 0.0131 0.0687 0.0665
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0052 0.0181 0.022
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0111 0.0458
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0165 0.0904 0.1641
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0165 0.0904 0.1232
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0165 0.0904 0.1604
Echinococcus multilocularis GPCR, family 2 0.0165 0.0904 0.0883
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0041 0.0092
Plasmodium vivax vivapain-3 0.0165 0.0906 0.5175
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Loa Loa (eye worm) hypothetical protein 0.008 0.0359 0.061
Giardia lamblia Hypothetical protein 0.0075 0.0332 0.1535
Brugia malayi RNA recognition motif domain containing protein 0.0051 0.0176 0.0319
Treponema pallidum ATP-dependent RNA helicase 0.0152 0.0824 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0051 0.0173 0.0314
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0196 0.1104 0.8873
Plasmodium vivax thioredoxin reductase, putative 0.0086 0.04 0.2276
Trypanosoma cruzi cruzipain precursor, putative 0.009 0.0425 0.0716
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0041 0.02
Echinococcus multilocularis hypothetical protein 0.0041 0.0111 0.0088
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Brugia malayi cathepsin B-like cysteine proteinase 0.0887 0.5512 1
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0075 0.0332 0.0541
Schistosoma mansoni hypothetical protein 0.0058 0.0219 0.0273
Leishmania major alpha glucosidase II subunit, putative 0.0029 0.0036 0.0019
Loa Loa (eye worm) hypothetical protein 0.0887 0.5512 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0165 0.0904 0.1233
Echinococcus granulosus snurportin 1 0.0289 0.1696 0.2339
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0218 0.1243 0.4745
Brugia malayi Cathepsin L-like precursor 0.0297 0.1749 0.3173
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0075 0.0332 0.0541
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0111 0.0411
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0051 0.0173 0.015
Brugia malayi calpain family protein 1 0.0108 0.0541 0.0981
Leishmania major cysteine peptidase A (CPA) 0.0297 0.1749 0.9027
Loa Loa (eye worm) calpain family protein 1 0.008 0.0359 0.061
Brugia malayi mbt repeat family protein 0.0044 0.0134 0.0243
Onchocerca volvulus 0.0111 0.0562 0.0798
Echinococcus granulosus cathepsin b 0.0887 0.5512 0.768
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.0332 0.0541
Giardia lamblia Cathepsin L precursor 0.0075 0.0332 0.1535
Echinococcus multilocularis cathepsin L cysteine protease 0.0297 0.1749 0.173
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0111 0.0458
Loa Loa (eye worm) glutathione reductase 0.0086 0.04 0.0686
Brugia malayi RNA binding protein 0.0051 0.0176 0.0319
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0176 0.0213
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0045 0.0139 0.1103
Loa Loa (eye worm) trypsin family protein 0.0052 0.0181 0.0286
Trypanosoma cruzi trypanothione reductase, putative 0.0086 0.04 0.067
Schistosoma mansoni cathepsin S (C01 family) 0.0075 0.0332 0.0431
Echinococcus multilocularis polycomb protein SCMH1 0.0044 0.0134 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1174 0.2086
Loa Loa (eye worm) hypothetical protein 0.0357 0.2127 0.3833
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0041 0.0015
Echinococcus multilocularis glycoprotein Antigen 5 0.0052 0.0181 0.0158
Echinococcus multilocularis cathepsin L 0.0075 0.0332 0.0309
Loa Loa (eye worm) inositol-1 0.0034 0.0068 0.008
Plasmodium falciparum serine repeat antigen 9 0.0075 0.0332 0.1885
Brugia malayi cathepsin F-like cysteine proteinase 0.0075 0.0332 0.0602
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0041 0.0044
Onchocerca volvulus 0.0297 0.1749 0.3013
Giardia lamblia Cathepsin L-like protease 0.0075 0.0332 0.1535
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0041 0.0092
Echinococcus granulosus eukaryotic initiation factor 4A 0.0152 0.0824 0.112
Loa Loa (eye worm) RNA binding protein 0.0051 0.0176 0.0278
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0152 0.0824 0.4137
Plasmodium falciparum serine repeat antigen 3 0.0075 0.0332 0.1885
Echinococcus granulosus geminin 0.0156 0.0846 0.1151
Mycobacterium tuberculosis Probable esterase LipL 0.0067 0.0277 0.0932
Loa Loa (eye worm) cysteine protease 0.0297 0.1749 0.3144
Plasmodium falciparum serine repeat antigen 2 0.0075 0.0332 0.1885
Brugia malayi cathepsin L precursor 0.0075 0.0332 0.0602
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0165 0.0906 0.1594
Loa Loa (eye worm) hypothetical protein 0.0067 0.0277 0.0462
Plasmodium vivax SET domain protein, putative 0.0111 0.0562 0.3203
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Brugia malayi MH2 domain containing protein 0.0118 0.0602 0.1093
Echinococcus multilocularis geminin 0.0156 0.0846 0.0824
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0165 0.0904 0.1232
Leishmania major cathepsin L-like protease 0.0297 0.1749 0.9027
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0332 0.0541
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0219 0.034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0522 0.3181 0.5771
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0069 0.0291 0.1653
Echinococcus multilocularis calpain A 0.0113 0.0572 0.055
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0175 0.0967 0.0946
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0029 0.0036 0.0023
Schistosoma mansoni hypothetical protein 0.0165 0.0904 0.1233
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0152 0.0824 0.1444
Loa Loa (eye worm) beta-lactamase 0.0067 0.0277 0.0462
Entamoeba histolytica hypothetical protein 0.0075 0.0332 0.1742
Schistosoma mansoni hypothetical protein 0.0156 0.0846 0.1151
Loa Loa (eye worm) hypothetical protein 0.0052 0.0181 0.0286
Mycobacterium ulcerans hypothetical protein 0.0067 0.0277 0.9443
Echinococcus multilocularis lysosomal alpha glucosidase 0.0131 0.0687 0.0665
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0326 0.1934 0.2673
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0041 0.0221
Mycobacterium tuberculosis Conserved protein 0.0067 0.0277 0.0932
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0056 0.0209 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1174 0.2086
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0111 0.0562 0.0753
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0152 0.0824 0.0802
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0041 0.0221
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0068 0.0064
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0067 0.0277 0.0355
Plasmodium falciparum cysteine proteinase falcipain 3 0.0297 0.1749 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Giardia lamblia Hypothetical protein 0.0075 0.0332 0.1535
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0111 0.0143
Leishmania major cathepsin L-like protease 0.0297 0.1749 0.9027
Brugia malayi Cathepsin L-like precursor 0.0297 0.1749 0.3173
Brugia malayi Probable ATP-dependent helicase DHX35 0.038 0.2274 0.4125
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0107 0.0536 0.0717
Echinococcus granulosus Mastin 0.0052 0.0181 0.022
Brugia malayi Papain family cysteine protease containing protein 0.0075 0.0332 0.0602
Entamoeba histolytica hypothetical protein 0.003 0.0044 0.0064
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0075 0.0332 0.0431
Schistosoma mansoni microtubule-associated protein tau 0.1147 0.7171 1
Echinococcus granulosus tar DNA binding protein 0.0051 0.0176 0.0213
Loa Loa (eye worm) hypothetical protein 0.0058 0.0219 0.0356
Echinococcus granulosus histone acetyltransferase MYST2 0.0051 0.0173 0.0209
Echinococcus granulosus GPCR family 2 0.0165 0.0904 0.1233
Entamoeba histolytica cysteine protease, putative 0.0165 0.0906 0.509
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0218 0.1243 0.4745
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0113 0.0572 0.055
Echinococcus granulosus cathepsin L 0.0075 0.0332 0.0431
Echinococcus granulosus polycomb protein SCMH1 0.0044 0.0134 0.0155
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0075 0.0332 0.1742
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0111 0.0458
Entamoeba histolytica cysteine protease, putative 0.0075 0.0332 0.1742
Loa Loa (eye worm) calpain 5 0.0029 0.0033 0.0017
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0196 0.1104 0.4193
Schistosoma mansoni hypothetical protein 0.003 0.0044 0.0028
Echinococcus granulosus enteropeptidase 0.0052 0.0181 0.022
Schistosoma mansoni hypothetical protein 0.0052 0.0181 0.022
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0111 0.0562 0.0753
Brugia malayi fibroinase precursor 0.0075 0.0332 0.0602
Echinococcus granulosus beta LACTamase domain containing family member 0.0067 0.0277 0.0355
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0034 0.0066 0.006
Trichomonas vaginalis penicillin-binding protein, putative 0.0067 0.0277 0.0441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.1749 0.3139
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0111 0.0122
Leishmania major cathepsin L-like protease 0.0297 0.1749 0.9027
Loa Loa (eye worm) calpain 0.0041 0.0111 0.0159
Entamoeba histolytica cysteine proteinase, putative 0.0207 0.1174 0.6652
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0165 0.0904 0.164
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0277 0.0441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.1749 0.3139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0127 0.0664 0.0896
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0086 0.04 0.1416
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0067 0.0277 0.0932
Schistosoma mansoni bromodomain containing protein 0.0059 0.023 0.0289
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0277 0.1573
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Trypanosoma cruzi major cysteine proteinase, putative 0.0075 0.0332 0.0546
Mycobacterium ulcerans lipase LipD 0.0067 0.0277 0.9443
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0075 0.0332 0.0431
Toxoplasma gondii ABC1 family protein 0.0067 0.0277 0.1422
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0075 0.0332 0.1885
Brugia malayi cathepsin F-like cysteine proteinase 0.009 0.0425 0.0772
Loa Loa (eye worm) hypothetical protein 0.0052 0.0181 0.0286
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.0332 0.0541
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0297 0.1749 0.3139
Schistosoma mansoni sex comb on midleg homolog 0.0044 0.0134 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0036 0.0007
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0069 0.0291 0.3513
Trypanosoma cruzi major cysteine proteinase, putative 0.0075 0.0332 0.0546
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0113 0.0572 0.0767
Giardia lamblia Cathepsin L-like protease 0.0075 0.0332 0.1535
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0181 0.022
Brugia malayi RNA, U transporter 1 0.0077 0.0342 0.0621
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0181 0.022
Loa Loa (eye worm) hypothetical protein 0.0152 0.0824 0.1459
Trichomonas vaginalis penicillin-binding protein, putative 0.0067 0.0277 0.0441
Mycobacterium tuberculosis Probable lipase LipE 0.0067 0.0277 0.0932
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0068 0.0057
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0075 0.0332 0.0541
Plasmodium vivax unspecified product 0.009 0.0425 0.2421
Brugia malayi Trypsin family protein 0.0052 0.0181 0.0328
Onchocerca volvulus 0.0052 0.0181 0.0087
Loa Loa (eye worm) hypothetical protein 0.0038 0.0095 0.013
Loa Loa (eye worm) hypothetical protein 0.0075 0.0332 0.0561
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0041 0.0015
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0068 0.0184
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0165 0.0904 0.1233
Brugia malayi Papain family cysteine protease containing protein 0.0165 0.0906 0.1644
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0034 0.0066 0.0043
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0041 0.02
Plasmodium falciparum cysteine repeat modular protein 1 0.0058 0.0219 0.1239
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0067 0.0277 0.9443
Plasmodium falciparum thioredoxin reductase 0.0086 0.04 0.2276
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0748 0.1014
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0906 0.509
Schistosoma mansoni sex comb on midleg homolog 0.0044 0.0134 0.0155
Trypanosoma cruzi cysteine protease, putative 0.0165 0.0906 0.1594
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0181 0.022
Onchocerca volvulus 0.0052 0.0181 0.0087
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0181 0.022
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0196 0.1104 0.4193
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.009 0.0425 0.0772
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0777 0.4808 0.8717
Leishmania major hypothetical protein, conserved 0.0058 0.0219 0.0979
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0111 0.0411
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0176 0.0213
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0075 0.0332 0.1742
Onchocerca volvulus 0.0052 0.0181 0.0087
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0075 0.0332 0.0561
Schistosoma mansoni cathepsin F (C01 family) 0.0207 0.1174 0.161
Echinococcus multilocularis SAM and MBT domain containing protein 0.0044 0.0134 0.0111
Echinococcus multilocularis calpain family protein 1, d 0.008 0.0359 0.0336
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0176 0.0213
Loa Loa (eye worm) hypothetical protein 0.0075 0.0332 0.0561
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0075 0.0332 0.0431
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0243 0.1104
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.003 0.0045 0.0342
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0041 0.0009
Echinococcus multilocularis histone acetyltransferase MYST2 0.0051 0.0173 0.015
Plasmodium vivax serine-repeat antigen (SERA) 0.0075 0.0332 0.1885
Giardia lamblia Cathepsin B precursor 0.0326 0.1934 1
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0277 0.0446
Loa Loa (eye worm) hypothetical protein 0.0067 0.028 0.0468
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Brugia malayi Bromodomain containing protein 0.007 0.03 0.0545
Leishmania major eukaryotic initiation factor 4a, putative 0.0152 0.0824 0.4162
Onchocerca volvulus Cathepsin L homolog 0.0075 0.0332 0.0369
Brugia malayi cathepsin L-like cysteine proteinase 0.0075 0.0332 0.0602
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0165 0.0906 0.4621
Schistosoma mansoni calpain C (C02 family) 0.0041 0.0111 0.0122
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0041 0.0025
Brugia malayi Trypsin family protein 0.0141 0.0748 0.1358
Loa Loa (eye worm) hypothetical protein 0.009 0.0425 0.0732
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0111 0.0122
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0152 0.0824 0.1444
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.0036 0.0021
Leishmania major hypothetical protein, conserved 0.0067 0.0277 0.1286
Leishmania major eukaryotic initiation factor 4a, putative 0.0152 0.0824 0.4162
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0111 0.0143
Plasmodium vivax vivapain-2 0.0297 0.1749 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0127 0.0664 0.0896
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0111 0.0562 0.054
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0075 0.0332 0.1535
Loa Loa (eye worm) hypothetical protein 0.0052 0.0181 0.0286
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.003 0.0044 0.002
Leishmania major cathepsin L-like protease 0.0297 0.1749 0.9027
Echinococcus multilocularis calpain 0.0041 0.0111 0.0088
Schistosoma mansoni inositol monophosphatase 0.0034 0.0068 0.0062
Leishmania major cathepsin L-like protease 0.0297 0.1749 0.9027
Trypanosoma cruzi cysteine proteinase, putative 0.0165 0.0906 0.1594
Brugia malayi Probable ClpP-like protease 0.0069 0.0291 0.0528
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0041 0.0015
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0041 0.0044
Onchocerca volvulus 0.0231 0.1322 0.2217
Schistosoma mansoni peptidase Clp (S14 family) 0.0069 0.0291 0.0374
Echinococcus multilocularis thioredoxin glutathione reductase 0.0087 0.0403 0.0381
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0041 0.0044
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0069 0.0291 0.1494
Schistosoma mansoni cathepsin C 0.0075 0.0332 0.0431
Entamoeba histolytica cysteine proteinase 1, putative 0.0165 0.0906 0.509
Loa Loa (eye worm) hypothetical protein 0.0141 0.0748 0.1321
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0067 0.0277 0.0932
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.0036 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0075 0.0332 0.0541
Giardia lamblia Cathepsin L precursor 0.0075 0.0332 0.1535
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0243 0.0795
Brugia malayi Papain family cysteine protease containing protein 0.0165 0.0906 0.1644
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0196 0.1104 0.4193
Brugia malayi Protein kinase domain containing protein 0.0058 0.0219 0.0397
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0207 0.1174 0.2083
Schistosoma mansoni hypothetical protein 0.0165 0.0904 0.1233
Brugia malayi Thioredoxin reductase 0.0086 0.04 0.0726
Brugia malayi Inositol-1 0.0034 0.0068 0.0123
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0052 0.0181 0.022
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0297 0.1749 0.3144
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0075 0.0332 0.0431
Plasmodium falciparum serine repeat antigen 5 0.0075 0.0332 0.1885
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0181 0.022
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0056 0.0209 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0332 0.0541
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0075 0.0332 0.1535
Loa Loa (eye worm) hypothetical protein 0.0231 0.1322 0.2366
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0243 0.1243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.0332 0.0541
Giardia lamblia Cathepsin B precursor 0.0075 0.0332 0.1535
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0041 0.0221
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0165 0.0904 0.1232
Onchocerca volvulus 0.0075 0.0332 0.0369
Plasmodium falciparum glutathione reductase 0.0086 0.04 0.2276
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0427 0.2575 1
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0051 0.0173 0.0209
Loa Loa (eye worm) ctsf protein 0.0297 0.1749 0.3144
Plasmodium falciparum thioredoxin reductase 0.003 0.0041 0.0221
Onchocerca volvulus 0.0052 0.0181 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.1749 0.3139
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0075 0.0332 0.1885
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.1749 0.9032
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0887 0.5512 0.768
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0152 0.0824 0.1444
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.1749 0.3139
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0131 0.0687 0.1209

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 50 uM Inhibitory concentration against human histone deacetylase ChEMBL. 14613312
IC50 (binding) > 50 uM Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells. ChEMBL. 12419380
IC50 (binding) > 50 uM Inhibitory concentration against human histone deacetylase ChEMBL. 14613312
IC50 (binding) > 50 uM Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells. ChEMBL. 12419380

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

2 literature references were collected for this gene.

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