Detailed information for compound 227471

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 334.799 | Formula: C20H15ClN2O
  • H donors: 1 H acceptors: 1 LogP: 3.45 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)C1(O)c2cc3ccccc3cc2C2=NCCN12
  • InChi: 1S/C20H15ClN2O/c21-16-7-5-15(6-8-16)20(24)18-12-14-4-2-1-3-13(14)11-17(18)19-22-9-10-23(19)20/h1-8,11-12,24H,9-10H2
  • InChiKey: UEQXHKUXJZQGHV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 3 620 aa 579 aa 33.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei metacaspase MCA2 0.0058 0.0599 0.7697
Echinococcus granulosus hypothetical protein 0.0029 0.0217 0.021
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Toxoplasma gondii hypothetical protein 0.0068 0.0743 0.492
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0086 0.0075
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0167 0.2088 0.2083
Schistosoma mansoni hypothetical protein 0.0019 0.0072 0.0061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Loa Loa (eye worm) hypothetical protein 0.0029 0.0213 0.0404
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0014 0.0011 0.0004
Echinococcus granulosus transient receptor potential cation channel 0.0015 0.0026 0.0018
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0086 0.0075
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0043 0.0405 0.1896
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.139
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0048 0.0182
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0011 0.0004
Brugia malayi hypothetical protein 0.0068 0.0743 0.139
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0086 0.0162
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0014 0.0011 0.0004
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.5156
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0545 0.0535
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0265 0.0255
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Brugia malayi nuclear receptor NHR-88 0.002 0.0086 0.0142
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus granulosus caspase 8 0.0058 0.0599 0.0592
Onchocerca volvulus 0.004 0.0354 0.0652
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0014 0.0011 0.0004
Echinococcus multilocularis shaker cognate 0.0014 0.0011 0.0004
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0014 0.0011 0.0004
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.5156
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.01 0.1573
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0297 0.3743
Echinococcus multilocularis two pore calcium channel protein 2 0.0014 0.0011 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0086 0.0078
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0167 0.2088 0.208
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Echinococcus granulosus FTZ F1 alpha 0.002 0.0086 0.0078
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Plasmodium falciparum amino acid transporter, putative 0.0068 0.0743 0.3524
Trypanosoma cruzi metacaspase 5, putative 0.0058 0.0599 0.7697
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0064
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Trypanosoma cruzi heat shock protein 85, putative 0.0056 0.0579 0.7443
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0086 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0011 0.0001
Brugia malayi Trypsin family protein 0.0019 0.0072 0.0116
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0029 0.0208 0.0201
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0014 0.0011 0.0004
Onchocerca volvulus 0.0052 0.0527 0.098
Trypanosoma brucei heat shock protein 90, putative 0.007 0.0775 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0068 0.0743 0.0736
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.01 0.1171
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.01 0.1573
Echinococcus multilocularis caspase 8 0.0058 0.0599 0.0592
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0064 0.0689 0.0679
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0265 0.0255
Loa Loa (eye worm) tumor suppressor 0.0349 0.4562 0.864
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0014 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0048 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0308 0.0899
Plasmodium falciparum metacaspase 1 0.0058 0.0599 0.283
Onchocerca volvulus 0.0054 0.0545 0.1014
Echinococcus multilocularis dna polymerase eta 0.0049 0.0476 0.0469
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0014 0.0011 0.0004
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0014 0.0011 0.0004
Echinococcus granulosus glycoprotein Antigen 5 0.0019 0.0072 0.0064
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0086 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.01 0.1171
Loa Loa (eye worm) endoplasmin 0.007 0.0775 0.1467
Loa Loa (eye worm) hypothetical protein 0.0058 0.0599 0.1134
Echinococcus multilocularis sodium leak channel non selective protein 0.0014 0.0011 0.0004
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.0208 0.0952
Schistosoma mansoni lamin 0.0029 0.0213 0.0203
Leishmania major hypothetical protein, unknown function 0.0014 0.0011 0.0003
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0014 0.0011 0.0004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0346 0.0339
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Trypanosoma cruzi metacaspase, putative 0.0058 0.0599 0.7697
Trypanosoma cruzi metacaspase, putative 0.0058 0.0599 0.7697
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.011 0.0103
Loa Loa (eye worm) hypothetical protein 0.003 0.0217 0.0411
Loa Loa (eye worm) heat shock protein 75 0.0029 0.0208 0.0395
Echinococcus granulosus tumor protein p63 0.0366 0.4802 0.4798
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0086 0.0078
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.01 0.0093
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0086 0.0142
Toxoplasma gondii heat shock protein HSP90 0.007 0.0775 0.5133
Plasmodium falciparum metacaspase-like protein 0.0058 0.0599 0.283
Trypanosoma brucei Metacaspase-4 0.0058 0.0599 0.7697
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Echinococcus granulosus sodium channel protein 0.0014 0.0011 0.0004
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0048 0.0041
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Entamoeba histolytica hypothetical protein 0.0039 0.0346 0.1615
Treponema pallidum sodium- and chloride- dependent transporter 0.0401 0.528 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0014 0.0011 0.0004
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0265 0.171
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Schistosoma mansoni polycystin 1-related 0.0022 0.011 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0086 0.0142
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0579 0.1718
Echinococcus multilocularis enteropeptidase 0.0019 0.0072 0.0064
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0086 0.0142
Loa Loa (eye worm) voltage-dependent calcium channel 0.0014 0.0011 0.002
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0048 0.0041
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0048 0.0041
Onchocerca volvulus Peroxidase homolog 0.004 0.0354 0.0652
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0634 0.4191
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0048 0.0495
Giardia lamblia Heat shock protein HSP 90-alpha 0.007 0.0775 0.3677
Trypanosoma brucei metacaspase 0.0058 0.0599 0.7697
Echinococcus granulosus transient receptor potential gamma protein 0.0014 0.0011 0.0004
Brugia malayi hypothetical protein 0.0108 0.1284 0.2417
Schistosoma mansoni lipoxygenase 0.0129 0.1577 0.1569
Echinococcus granulosus calcium activated potassium channel 0.0014 0.0011 0.0004
Brugia malayi Temporarily assigned gene name protein 44 0.003 0.0217 0.0391
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.139
Echinococcus multilocularis short transient receptor potential channel 6 0.0015 0.0026 0.0018
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus granulosus two pore calcium channel protein 2 0.0014 0.0011 0.0004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.492
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0086 0.0075
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.011 0.0103
Onchocerca volvulus Huntingtin homolog 0.0108 0.1284 0.2417
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0068 0.0743 0.0736
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0011 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Leishmania major hypothetical protein, conserved 0.0014 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0086 0.0078
Brugia malayi ecdysteroid receptor 0.002 0.0086 0.0142
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Loa Loa (eye worm) doublecortin family protein 0.0022 0.011 0.0208
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0086 0.0078
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.01 0.009
Echinococcus multilocularis glycoprotein Antigen 5 0.0019 0.0072 0.0064
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Onchocerca volvulus Peroxidase homolog 0.004 0.0354 0.0652
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0265 0.0258
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0056 0.0579 1
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Schistosoma mansoni heat shock protein 0.0029 0.0208 0.0198
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0048 0.0041
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0167 0.2088 1
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0354 0.0671
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0215 0.2745 0.274
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.5156
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0056 0.0579 1
Echinococcus multilocularis caspase 0.0215 0.2745 0.274
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Echinococcus granulosus dnaJ subfamily B 0.0444 0.5852 0.5849
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0043 0.0405 0.0398
Echinococcus multilocularis calcium activated potassium channel 0.0014 0.0011 0.0004
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0028 0.0034
Loa Loa (eye worm) hypothetical protein 0.0108 0.1284 0.2433
Echinococcus granulosus ryanodine receptor 44f 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Echinococcus multilocularis voltage dependent calcium channel 0.0014 0.0011 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0048 0.0041
Schistosoma mansoni nuclear hormone receptor 0.002 0.0086 0.0075
Schistosoma mansoni eyes absent homolog 0.0096 0.1116 0.1106
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0308 0.0584
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.011 0.0103
Loa Loa (eye worm) solute carrier family 6 member 4 0.0401 0.528 1
Schistosoma mansoni intermediate filament proteins 0.0029 0.0213 0.0203
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.01 0.1171
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Loa Loa (eye worm) heat shock protein 90 0.007 0.0775 0.1467
Schistosoma mansoni rotamase 0.0036 0.0308 0.0298
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.01 0.043
Echinococcus granulosus dna polymerase kappa 0.0021 0.01 0.0093
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0208 0.0597
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0014 0.0011 0.0003
Echinococcus multilocularis dna polymerase kappa 0.0021 0.01 0.0093
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0401 0.528 0.5275
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0048 0.0182
Plasmodium vivax amine transporter, putative 0.0068 0.0743 0.3524
Brugia malayi Pre-SET motif family protein 0.0033 0.0265 0.0483
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0297 0.3743
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.01 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0086 0.0142
Plasmodium vivax heat shock protein, putative 0.0029 0.0208 0.0952
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0086 0.0078
Schistosoma mansoni rab6-interacting 0.0022 0.011 0.0099
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Echinococcus granulosus protein quaking 0.0029 0.0217 0.021
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0265 0.0258
Echinococcus granulosus endoplasmin 0.0056 0.0579 0.0572
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0354 0.0671
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus Mastin 0.0019 0.0072 0.0064
Trypanosoma brucei unspecified product 0.0014 0.0012 0.0014
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0043 0.0405 0.0748
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.1407
Echinococcus multilocularis two pore calcium channel protein 1 0.0014 0.0011 0.0004
Giardia lamblia DINP protein human, muc B family 0.0021 0.01 0.043
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Echinococcus multilocularis tumor protein p63 0.0366 0.4802 0.4798
Echinococcus multilocularis transient receptor potential gamma protein 0.0014 0.0011 0.0004
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0476 0.0883
Plasmodium falciparum transporter, putative 0.0068 0.0743 0.3524
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0048 0.0038
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.01 0.0189
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0048 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0086 0.0142
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Brugia malayi intermediate filament protein 0.0029 0.0213 0.0385
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0014 0.0011 0.0003
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.119
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0297 0.3743
Echinococcus multilocularis sodium and chloride dependent glycine 0.0068 0.0743 0.0736
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0011 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0599 0.283
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0014 0.0011 0.0003
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0048 0.0254
Brugia malayi Blistered cuticle protein 3 0.004 0.0354 0.0652
Brugia malayi Trypsin family protein 0.0019 0.0072 0.0116
Leishmania major DNA polymerase eta, putative 0.0034 0.028 0.352
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0167 0.2088 0.3943
Schistosoma mansoni endoplasmin 0.007 0.0775 0.0765
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0011 0.002
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0011 0.0004
Schistosoma mansoni sodium-dependent amino acid transporter 0.0068 0.0743 0.0733
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0086 0.0078
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0014 0.0011 0.0004
Echinococcus granulosus dna polymerase eta 0.0049 0.0476 0.0469
Echinococcus granulosus voltage dependent calcium channel 0.0014 0.0011 0.0004
Loa Loa (eye worm) ryanodine receptor 0.0014 0.0011 0.002
Brugia malayi hypothetical protein 0.0256 0.3305 0.6253
Schistosoma mansoni DNA polymerase eta 0.0049 0.0476 0.0466
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0043 0.0405 0.1896
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0011 0.0004
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.01 0.027
Echinococcus multilocularis transmembrane protease serine 3 0.0019 0.0072 0.0064
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Schistosoma mansoni lipoxygenase 0.0091 0.1047 0.1038
Toxoplasma gondii hypothetical protein 0.0124 0.1499 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.1407
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0043 0.0405 0.5156
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0068 0.0743 0.0736
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0086 0.0142
Trypanosoma brucei unspecified product 0.0021 0.01 0.1171
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0167 0.2088 0.6277
Onchocerca volvulus Peroxidasin homolog 0.004 0.0354 0.0652
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0213 0.0385
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.01 0.1171
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0011 0.0001
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.5156
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0011 0.0001
Giardia lamblia Rab geranylgeranyltransferase 0.0043 0.0405 0.1896
Plasmodium vivax metacaspase 1, putative 0.0058 0.0599 0.283
Echinococcus granulosus heat shock protein 90 0.007 0.0775 0.0768
Loa Loa (eye worm) hypothetical protein 0.0033 0.0265 0.0502
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0011 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Schistosoma mansoni caspase-3 (C14 family) 0.0215 0.2745 0.2738
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0129 0.1577 0.1571
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.492
Echinococcus multilocularis musashi 0.0029 0.0213 0.0206
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0014 0.0011 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0011 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0086 0.0162
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0043 0.0405 0.1896
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Schistosoma mansoni endoplasmin 0.007 0.0775 0.0765
Echinococcus multilocularis short transient receptor potential channel 6 0.0014 0.0011 0.0004
Echinococcus granulosus heat shock protein 0.007 0.0775 0.0768
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0056 0.0579 1
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0167 0.2088 1
Brugia malayi hypothetical protein 0.0019 0.0072 0.0116
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Onchocerca volvulus 0.0068 0.0743 0.139
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Giardia lamblia Grp94/Hsp90 0.0056 0.0579 0.2737
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Onchocerca volvulus Chorion peroxidase homolog 0.004 0.0354 0.0652
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0086 0.0162
Schistosoma mansoni hypothetical protein 0.0029 0.0217 0.0206
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0029 0.0208 0.0201
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0012 0.0014
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0129 0.1577 0.1571
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.01 0.017
Schistosoma mansoni hypothetical protein 0.0039 0.0346 0.0336
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0019 0.0072 0.0116
Loa Loa (eye worm) hypothetical protein 0.0049 0.0476 0.0902
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0014
Schistosoma mansoni cpg binding protein 0.0031 0.0239 0.0229
Onchocerca volvulus 0.0022 0.011 0.0188
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0405 0.5156
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0086 0.0078
Echinococcus multilocularis lamin 0.0029 0.0213 0.0206
Trypanosoma brucei DNA polymerase eta, putative 0.0049 0.0476 0.6091
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.028 0.352
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Onchocerca volvulus 0.0019 0.0072 0.0116
Echinococcus multilocularis RUN 0.0022 0.011 0.0103
Trypanosoma brucei metacaspase 5, putative 0.0058 0.0599 0.7697
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Schistosoma mansoni sodium/chloride dependent transporter 0.0068 0.0743 0.0733
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Brugia malayi Doublecortin family protein 0.0022 0.011 0.0188
Schistosoma mansoni survival motor neuron protein 0.0052 0.0527 0.0517
Entamoeba histolytica hypothetical protein 0.0039 0.0346 0.1615
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0068 0.0743 0.0736
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0014 0.0011 0.0003
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0086 0.0078
Echinococcus granulosus short transient receptor potential channel 6 0.0014 0.0011 0.0004
Schistosoma mansoni caspase-7 (C14 family) 0.0215 0.2745 0.2738
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.011 0.0103
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0043 0.0405 0.0398
Entamoeba histolytica heat shock protein 90, putative 0.007 0.0775 0.3677
Onchocerca volvulus 0.0029 0.0213 0.0385
Trypanosoma cruzi metacaspase, putative 0.0058 0.0599 0.7697
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0297 0.1921
Echinococcus multilocularis expressed protein 0.0036 0.0308 0.0301
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Trypanosoma brucei metacaspase MCA3 0.0058 0.0599 0.7697
Schistosoma mansoni hypothetical protein 0.0052 0.0527 0.0517
Schistosoma mansoni loxhd1 0.0022 0.011 0.0099
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0058 0.0599 0.3951
Brugia malayi hypothetical protein 0.0039 0.0346 0.0637
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0011 0.0001
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0354 0.0671
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0011 0.0004
Echinococcus multilocularis cpg binding protein 0.0033 0.0263 0.0256
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0011 0.0004
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0213 0.0404
Onchocerca volvulus 0.0029 0.0213 0.0385
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0014 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Trypanosoma cruzi heat shock protein, putative 0.0029 0.0208 0.2588
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.011 0.0208
Echinococcus multilocularis transient receptor potential cation channel 0.0015 0.0026 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus granulosus expressed protein 0.0036 0.0308 0.0301
Loa Loa (eye worm) hypothetical protein 0.0022 0.011 0.0208
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis transfer RNA-Gly 0.0014 0.0011 0.0004
Onchocerca volvulus 0.0068 0.0743 0.139
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.011 0.0477
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Onchocerca volvulus Cell death protein 3 homolog 0.0058 0.0599 0.1116
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.2896 0.5485
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Echinococcus granulosus sodium and chloride dependent glycine 0.0068 0.0743 0.0736
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Schistosoma mansoni peroxidasin 0.004 0.0354 0.0344
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0068 0.0743 0.0736
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0048 0.0495
Schistosoma mansoni caspase-7 (C14 family) 0.0058 0.0599 0.0589
Schistosoma mansoni lamin 0.0029 0.0213 0.0203
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0014 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Schistosoma mansoni heat shock protein 0.007 0.0775 0.0765
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Schistosoma mansoni microtubule-associated protein tau 0.0748 1 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0014 0.0011 0.0004
Trypanosoma brucei heat shock protein 84, putative 0.0029 0.0208 0.2588
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0048 0.0092
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0019 0.0072 0.0064
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0167 0.2088 0.3955
Echinococcus granulosus cpg binding protein 0.0033 0.0263 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0086 0.0162
Trichomonas vaginalis set domain proteins, putative 0.0258 0.332 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Trypanosoma cruzi heat shock protein 90, putative 0.0042 0.0381 0.4855
Trypanosoma brucei Heat shock protein 83, putative 0.007 0.0775 1
Leishmania major DNA polymerase eta, putative 0.0049 0.0476 0.6091
Brugia malayi hypothetical protein 0.004 0.0354 0.0652
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0029 0.0208 0.0375
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0579 0.1718
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0014 0.0011 0.0004
Plasmodium vivax heat shock protein 90, putative 0.0029 0.0208 0.0952
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0068 0.0743 1
Loa Loa (eye worm) trypsin family protein 0.0019 0.0072 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Toxoplasma gondii hypothetical protein 0.0068 0.0743 0.492
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0014 0.0011 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0058 0.0599 0.0589
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0086 0.0142
Loa Loa (eye worm) hypothetical protein 0.0054 0.0545 0.1033
Toxoplasma gondii hypothetical protein 0.0043 0.0405 0.2647
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0014 0.0011 0.0003
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus voltage gated hydrogen channel 1 0.0014 0.0011 0.0004
Trichomonas vaginalis endoplasmin, putative 0.0043 0.0404 0.1188
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0056 0.0579 0.0572
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0401 0.528 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0014 0.0011 0.0004
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.3305 0.33
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0011 0.0001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.01 0.1171
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0265 0.0258
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0527 0.098
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0068 0.0743 0.139
Echinococcus granulosus caspase 2 0.0058 0.0599 0.0592
Schistosoma mansoni thyroid hormone receptor 0.002 0.0086 0.0075
Trypanosoma cruzi Heat shock protein 83, putative 0.007 0.0775 1
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0775 1
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0167 0.2088 0.2083
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0011 0.002
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0476 0.6091
Echinococcus granulosus potassium large conductance calcium activated 0.0014 0.0011 0.0004
Trypanosoma cruzi metacaspase, putative 0.0058 0.0599 0.7697
Loa Loa (eye worm) hypothetical protein 0.0096 0.1116 0.2113
Echinococcus granulosus shaker cognate 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Loa Loa (eye worm) hypothetical protein 0.0401 0.528 1
Echinococcus granulosus serotonin transporter 0.0401 0.528 0.5276
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0011 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.01 0.1171
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Brugia malayi Trypsin family protein 0.0019 0.0072 0.0116
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0086 0.0142
Echinococcus granulosus peroxidasin 0.004 0.0354 0.0347
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0167 0.2088 0.6277
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0058 0.0599 0.1116
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0579 0.1718
Onchocerca volvulus Dual oxidase homolog 0.004 0.0354 0.0652
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0014 0.0011 0.0004
Mycobacterium ulcerans hypothetical protein 0.0019 0.0072 0.1072
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0743 0.3524
Trichomonas vaginalis rotamase, putative 0.0036 0.0308 0.0899
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.492
Echinococcus granulosus intermediate filament protein 0.0029 0.0213 0.0206
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0167 0.2088 1
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0405 0.5156
Onchocerca volvulus 0.0043 0.0405 0.0748
Brugia malayi hypothetical protein 0.0022 0.011 0.0188
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0086 0.0078
Schistosoma mansoni heat shock protein 0.007 0.0775 0.0765
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0028 0.0054
Echinococcus multilocularis microtubule associated protein 2 0.0748 1 1
Echinococcus multilocularis caspase 3 0.0158 0.1962 0.1956
Onchocerca volvulus 0.0031 0.0239 0.0434
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0011 0.0004
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0011 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0011 0.0004
Echinococcus multilocularis voltage dependent calcium channel 0.0014 0.0011 0.0004
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.011 0.0103
Schistosoma mansoni coup transcription factor 0.002 0.0086 0.0075
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Brugia malayi hypothetical protein 0.0022 0.011 0.0188
Schistosoma mansoni sodium/chloride dependent transporter 0.0401 0.528 0.5275
Echinococcus granulosus heat shock protein 90 0.0056 0.0579 0.0572
Schistosoma mansoni cpg binding protein 0.0033 0.0263 0.0253
Echinococcus multilocularis heat shock protein 90 0.0056 0.0579 0.0572
Brugia malayi Cell death protein 3 precursor 0.0058 0.0599 0.1116
Plasmodium falciparum heat shock protein 90 0.007 0.0775 0.3677
Onchocerca volvulus 0.0401 0.528 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0043 0.0405 0.5156
Echinococcus granulosus hypothetical protein 0.0014 0.0011 0.0004
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.01 0.1573
Schistosoma mansoni thyroid hormone receptor 0.002 0.0086 0.0075
Loa Loa (eye worm) norepinephrine transporter 0.0401 0.528 1
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0011 0.0004
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0043 0.0405 0.0766
Loa Loa (eye worm) hypothetical protein 0.0167 0.2088 0.3955
Schistosoma mansoni sodium/chloride dependent transporter 0.0068 0.0743 0.0733
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0019 0.0072 0.0064
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0014 0.0011 0.0004
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0346 0.0336
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0048 0.0495
Brugia malayi CXXC zinc finger family protein 0.0031 0.0239 0.0434
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0297 0.1376
Echinococcus granulosus transmembrane protease serine 3 0.0019 0.0072 0.0064
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0011 0.0004
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0086 0.0075
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0014 0.0011 0.0004
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus enteropeptidase 0.0019 0.0072 0.0064
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0086 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0012 0.0014
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Onchocerca volvulus 0.0019 0.0072 0.0116
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0086 0.0142
Brugia malayi nuclear hormone receptor 0.002 0.0086 0.0142
Mycobacterium ulcerans heat shock protein 90 0.0056 0.0579 1
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0029 0.0208 0.0952
Echinococcus multilocularis lamin dm0 0.0029 0.0213 0.0206
Schistosoma mansoni hypothetical protein 0.0019 0.0072 0.0061
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0297 0.3743
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0265 0.0255
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0014 0.0011 0.0004
Echinococcus granulosus lamin dm0 0.0029 0.0213 0.0206
Loa Loa (eye worm) voltage-gated calcium channel 0.0014 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0043 0.0405 0.0398
Toxoplasma gondii heat shock protein 90, putative 0.007 0.0775 0.5133
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0775 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Brugia malayi heat shock protein 90 0.007 0.0775 0.145
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.139
Onchocerca volvulus 0.002 0.0086 0.0142
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Echinococcus multilocularis transient receptor potential cation channel 0.0015 0.0026 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0086 0.0162
Entamoeba histolytica hypothetical protein 0.0039 0.0346 0.1615
Giardia lamblia Rab geranylgeranyltransferase 0.0167 0.2088 1
Onchocerca volvulus 0.0019 0.0072 0.0116
Echinococcus granulosus caspase 0.0215 0.2745 0.274
Schistosoma mansoni rab6-interacting 0.0022 0.011 0.0099
Loa Loa (eye worm) hypothetical protein 0.0015 0.0026 0.0048
Leishmania major heat shock protein, putative 0.0029 0.0208 0.2588
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis protein quaking 0.0029 0.0217 0.021
Onchocerca volvulus 0.0019 0.0072 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0086 0.0142
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Toxoplasma gondii Hsp90 domain-containing protein 0.0029 0.0208 0.1328
Loa Loa (eye worm) hypothetical protein 0.0096 0.1116 0.2113
Onchocerca volvulus 0.0068 0.0743 0.139
Trypanosoma brucei unspecified product 0.0014 0.0012 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0086 0.0162
Trypanosoma cruzi heat shock protein 90, putative 0.0056 0.0579 0.7443
Echinococcus multilocularis dnaJ subfamily B 0.0444 0.5852 0.5849
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.01 0.1171
Loa Loa (eye worm) hypothetical protein 0.0401 0.528 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Toxoplasma gondii hypothetical protein 0.0014 0.0011 0.0001
Schistosoma mansoni hypothetical protein 0.0022 0.011 0.0099
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0014 0.0011 0.0004
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0086 0.0078
Echinococcus multilocularis ryanodine receptor 44f 0.0014 0.0011 0.0004
Onchocerca volvulus 0.0022 0.011 0.0188
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0215 0.2745 0.274
Schistosoma mansoni transient receptor potential channel 0.0015 0.0026 0.0015
Echinococcus granulosus sodium leak channel non selective protein 0.0014 0.0011 0.0004
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0048 0.0495
Echinococcus granulosus RUN 0.0022 0.011 0.0103
Trypanosoma cruzi heat shock protein 90, putative 0.007 0.0775 1
Entamoeba histolytica hypothetical protein 0.0039 0.0346 0.1615
Schistosoma mansoni cpg binding protein 0.0033 0.0263 0.0253
Loa Loa (eye worm) hypothetical protein 0.0108 0.1284 0.2433
Onchocerca volvulus 0.004 0.0354 0.0652
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Onchocerca volvulus Huntingtin homolog 0.0108 0.1284 0.2417
Onchocerca volvulus 0.0033 0.0265 0.0483
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0086 0.0078
Schistosoma mansoni hypothetical protein 0.0029 0.0217 0.0206
Echinococcus multilocularis caspase 2 0.0058 0.0599 0.0592
Loa Loa (eye worm) hypothetical protein 0.0256 0.3305 0.626
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0775 1
Brugia malayi tumor suppressor. 0.0349 0.4562 0.8637
Echinococcus multilocularis peroxidasin 0.004 0.0354 0.0347
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Plasmodium vivax endoplasmin, putative 0.007 0.0775 0.3677
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.028 0.1807
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0265 0.0255
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0048 0.0041
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Onchocerca volvulus 0.0019 0.0072 0.0116
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0086 0.0142
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.01 0.1573
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0011 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis serotonin transporter 0.0401 0.528 0.5276
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0086 0.0142
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0086 0.0162
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0011 0.002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0086 0.0142
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Loa Loa (eye worm) blistered cuticle protein 3 0.004 0.0354 0.0671
Brugia malayi olfactory channel protein osm-9 0.0015 0.0026 0.0028
Schistosoma mansoni peroxidasin 0.004 0.0354 0.0344
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.3305 0.33
Echinococcus multilocularis heat shock protein 90 0.007 0.0775 0.0768
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0086 0.0142
Toxoplasma gondii heat shock protein 75, putative 0.0029 0.0208 0.1328
Echinococcus multilocularis potassium large conductance calcium activated 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Brugia malayi isocitrate dehydrogenase 0.0017 0.0048 0.0072
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0086 0.0075
Brugia malayi hypothetical protein 0.003 0.0217 0.0391
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0011 0.0004
Echinococcus granulosus caspase 3 0.0158 0.1962 0.1956
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Brugia malayi Pre-SET motif family protein 0.0226 0.2896 0.5476
Brugia malayi Trypsin-like protease protein 5 0.0019 0.0072 0.0116
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0405 0.5156
Echinococcus multilocularis Mastin 0.0019 0.0072 0.0064
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.011 0.0103
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0086 0.0078
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0014 0.0011 0.0004
Echinococcus granulosus two pore calcium channel protein 1 0.0014 0.0011 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0011 0.0004
Echinococcus multilocularis endoplasmin 0.0056 0.0579 0.0572
Loa Loa (eye worm) calcium channel 0.0014 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0048 0.0254
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Loa Loa (eye worm) hypothetical protein 0.0058 0.0599 0.1134
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0308 0.0565
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0058 0.0599 0.3951
Echinococcus granulosus lamin 0.0029 0.0213 0.0206
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.01 0.1171
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.011 0.0477
Loa Loa (eye worm) serotonin transporter b 0.0401 0.528 1
Trichomonas vaginalis rotamase, putative 0.0035 0.0297 0.0864
Plasmodium falciparum endoplasmin, putative 0.0043 0.0404 0.1892
Brugia malayi Endoplasmin precursor 0.007 0.0775 0.145
Loa Loa (eye worm) TOPoisomerase family member 0.0014 0.0011 0.002
Plasmodium vivax SET domain protein, putative 0.0033 0.0265 0.1225
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Plasmodium vivax heat shock protein 86, putative 0.007 0.0775 0.3677
Trypanosoma brucei heat shock protein 90, putative 0.007 0.0775 1
Onchocerca volvulus 0.0259 0.3335 0.631
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0014 0.0011 0.0004
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0167 0.2088 0.6277
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Trypanosoma cruzi metacaspase 5, putative 0.0058 0.0599 0.7697
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.024 0.0232
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0346 0.0339
Entamoeba histolytica heat shock protein 90, putative 0.007 0.0775 0.3677
Brugia malayi Peroxidasin 0.004 0.0354 0.0652
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0043 0.0405 0.5156
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0014 0.0011 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Leishmania major metacaspase, putative 0.0058 0.0599 0.7697
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0014 0.0011 0.002
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0058 0.0599 0.3951
Brugia malayi Trypsin family protein 0.0019 0.0072 0.0116
Loa Loa (eye worm) ion channel NompC 0.0014 0.0011 0.002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Giardia lamblia Heat shock protein HSP 90-alpha 0.0056 0.0579 0.2737
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0056 0.0579 0.7443
Echinococcus multilocularis conserved hypothetical protein 0.0014 0.0011 0.0004
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0086 0.0142
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0068 0.0743 0.0733
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0014 0.0011 0.0004
Onchocerca volvulus 0.004 0.0354 0.0652
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0014 0.0011 0.0004
Onchocerca volvulus Peroxidasin homolog 0.004 0.0354 0.0652
Trichomonas vaginalis heat shock protein, putative 0.007 0.0775 0.2308
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0014 0.0011 0.0004
Echinococcus granulosus TRP transient receptor potential channel 0.0014 0.0011 0.0004
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.073 0.0721
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0011 0.0004
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus short transient receptor potential channel 6 0.0015 0.0026 0.0018
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0043 0.0405 0.0398
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0213 0.0404
Treponema pallidum heat shock protein 90 0.0056 0.0579 0.1079
Echinococcus granulosus voltage dependent calcium channel 0.0014 0.0011 0.0004
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0014 0.0011 0.0004
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.01 0.027
Loa Loa (eye worm) hypothetical protein 0.0029 0.0206 0.039
Onchocerca volvulus 0.0019 0.0072 0.0116
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0404 0.1188
Echinococcus multilocularis heat shock protein 0.007 0.0775 0.0768
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Schistosoma mansoni hypothetical protein 0.0444 0.5852 0.5848
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0086 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0086 0.0142
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0086 0.0142
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis sodium channel protein 0.0014 0.0011 0.0004
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Brugia malayi steroid hormone receptor 0.002 0.0086 0.0142
Loa Loa (eye worm) hypothetical protein 0.0401 0.528 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0011 0.0004
Echinococcus granulosus sodium and chloride dependent glycine 0.0068 0.0743 0.0736
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0019 0.0072 0.0064
Leishmania major DNA polymerase kappa, putative 0.0021 0.01 0.1171
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0086 0.0142
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0068 0.0743 0.0736
Brugia malayi hypothetical protein 0.0096 0.1116 0.2097
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0124 0.1499 0.4497
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0068 0.0743 0.0736
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0068 0.0743 0.0733
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0086 0.0075
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0354 0.0671
Brugia malayi Hsp90 protein 0.0029 0.0208 0.0375
Toxoplasma gondii hypothetical protein 0.0014 0.0011 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0239 0.0453
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0086 0.0078
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.0208 0.0952
Echinococcus multilocularis sodium and chloride dependent glycine 0.0068 0.0743 0.0736
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0086 0.0075

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 36.1 nM Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane. ChEMBL. 12213054
IC50 (binding) = 36.1 nM Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane. ChEMBL. 12213054
Ratio (functional) = 1.3 Ratio of the IC50 value of Mazindol to that of the compound in guinea pig was determined ChEMBL. 12213054
Ratio (functional) = 1.3 Ratio of the IC50 value of Mazindol to that of the compound in guinea pig was determined ChEMBL. 12213054

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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