Detailed information for compound 227472

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 334.799 | Formula: C20H15ClN2O
  • H donors: 1 H acceptors: 1 LogP: 3.45 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)C1(O)N2CCN=C2c2c1c1ccccc1cc2
  • InChi: 1S/C20H15ClN2O/c21-15-8-6-14(7-9-15)20(24)18-16-4-2-1-3-13(16)5-10-17(18)19-22-11-12-23(19)20/h1-10,24H,11-12H2
  • InChiKey: LQCWQIGQIHPKEY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 3 620 aa 579 aa 33.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax heat shock protein 86, putative 0.007 0.0775 0.3677
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Trypanosoma brucei heat shock protein 90, putative 0.007 0.0775 1
Onchocerca volvulus 0.0259 0.3335 0.631
Loa Loa (eye worm) serotonin transporter b 0.0401 0.528 1
Trichomonas vaginalis rotamase, putative 0.0035 0.0297 0.0864
Plasmodium falciparum endoplasmin, putative 0.0043 0.0404 0.1892
Plasmodium vivax SET domain protein, putative 0.0033 0.0265 0.1225
Brugia malayi Endoplasmin precursor 0.007 0.0775 0.145
Loa Loa (eye worm) TOPoisomerase family member 0.0014 0.0011 0.002
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0014 0.0011 0.0003
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0043 0.0405 0.5156
Brugia malayi Peroxidasin 0.004 0.0354 0.0652
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0014 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Leishmania major metacaspase, putative 0.0058 0.0599 0.7697
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0167 0.2088 0.6277
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0014 0.0011 0.0004
Entamoeba histolytica heat shock protein 90, putative 0.007 0.0775 0.3677
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.024 0.0232
Trypanosoma cruzi metacaspase 5, putative 0.0058 0.0599 0.7697
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0346 0.0339
Giardia lamblia Heat shock protein HSP 90-alpha 0.0056 0.0579 0.2737
Echinococcus multilocularis conserved hypothetical protein 0.0014 0.0011 0.0004
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0056 0.0579 0.7443
Brugia malayi Trypsin family protein 0.0019 0.0072 0.0116
Loa Loa (eye worm) ion channel NompC 0.0014 0.0011 0.002
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0058 0.0599 0.3951
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.073 0.0721
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0011 0.0004
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Echinococcus granulosus TRP transient receptor potential channel 0.0014 0.0011 0.0004
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus granulosus short transient receptor potential channel 6 0.0015 0.0026 0.0018
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0043 0.0405 0.0398
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0086 0.0142
Trichomonas vaginalis heat shock protein, putative 0.007 0.0775 0.2308
Onchocerca volvulus Peroxidasin homolog 0.004 0.0354 0.0652
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0014 0.0011 0.0004
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0068 0.0743 0.0733
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0014 0.0011 0.0004
Onchocerca volvulus 0.004 0.0354 0.0652
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Echinococcus multilocularis heat shock protein 0.007 0.0775 0.0768
Schistosoma mansoni hypothetical protein 0.0444 0.5852 0.5848
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0404 0.1188
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0086 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0086 0.0142
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0014 0.0011 0.0004
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0213 0.0404
Treponema pallidum heat shock protein 90 0.0056 0.0579 0.1079
Echinococcus granulosus voltage dependent calcium channel 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0206 0.039
Onchocerca volvulus 0.0019 0.0072 0.0116
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.01 0.027
Brugia malayi steroid hormone receptor 0.002 0.0086 0.0142
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0011 0.0004
Echinococcus granulosus sodium and chloride dependent glycine 0.0068 0.0743 0.0736
Loa Loa (eye worm) hypothetical protein 0.0401 0.528 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis sodium channel protein 0.0014 0.0011 0.0004
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0086 0.0142
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Brugia malayi hypothetical protein 0.0096 0.1116 0.2097
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0068 0.0743 0.0736
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0124 0.1499 0.4497
Leishmania major DNA polymerase kappa, putative 0.0021 0.01 0.1171
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0086 0.0142
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0068 0.0743 0.0736
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0019 0.0072 0.0064
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0239 0.0453
Brugia malayi Hsp90 protein 0.0029 0.0208 0.0375
Toxoplasma gondii hypothetical protein 0.0014 0.0011 0.0001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0086 0.0075
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.0208 0.0952
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0086 0.0078
Echinococcus multilocularis sodium and chloride dependent glycine 0.0068 0.0743 0.0736
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0068 0.0743 0.0733
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0354 0.0671
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0086 0.0075
Echinococcus multilocularis dnaJ subfamily B 0.0444 0.5852 0.5849
Trypanosoma cruzi heat shock protein 90, putative 0.0056 0.0579 0.7443
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.01 0.1171
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0086 0.0162
Loa Loa (eye worm) hypothetical protein 0.0401 0.528 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Onchocerca volvulus 0.0068 0.0743 0.139
Trypanosoma brucei unspecified product 0.0014 0.0012 0.0014
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0048 0.0495
Echinococcus granulosus RUN 0.0022 0.011 0.0103
Echinococcus granulosus sodium leak channel non selective protein 0.0014 0.0011 0.0004
Schistosoma mansoni transient receptor potential channel 0.0015 0.0026 0.0015
Loa Loa (eye worm) hypothetical protein 0.0108 0.1284 0.2433
Entamoeba histolytica hypothetical protein 0.0039 0.0346 0.1615
Trypanosoma cruzi heat shock protein 90, putative 0.007 0.0775 1
Schistosoma mansoni cpg binding protein 0.0033 0.0263 0.0253
Toxoplasma gondii hypothetical protein 0.0014 0.0011 0.0001
Schistosoma mansoni hypothetical protein 0.0022 0.011 0.0099
Echinococcus multilocularis ryanodine receptor 44f 0.0014 0.0011 0.0004
Onchocerca volvulus 0.0022 0.011 0.0188
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0215 0.2745 0.274
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0014 0.0011 0.0004
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Echinococcus multilocularis caspase 2 0.0058 0.0599 0.0592
Loa Loa (eye worm) hypothetical protein 0.0256 0.3305 0.626
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Plasmodium vivax endoplasmin, putative 0.007 0.0775 0.3677
Brugia malayi tumor suppressor. 0.0349 0.4562 0.8637
Echinococcus multilocularis peroxidasin 0.004 0.0354 0.0347
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0775 1
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Onchocerca volvulus 0.004 0.0354 0.0652
Schistosoma mansoni hypothetical protein 0.0029 0.0217 0.0206
Onchocerca volvulus Huntingtin homolog 0.0108 0.1284 0.2417
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0086 0.0078
Onchocerca volvulus 0.0033 0.0265 0.0483
Onchocerca volvulus 0.0019 0.0072 0.0116
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0086 0.0142
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.01 0.1573
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.028 0.1807
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0048 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0265 0.0255
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis serotonin transporter 0.0401 0.528 0.5276
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0086 0.0162
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0011 0.002
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0086 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0086 0.0142
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0011 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0011 0.0004
Brugia malayi isocitrate dehydrogenase 0.0017 0.0048 0.0072
Echinococcus multilocularis potassium large conductance calcium activated 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0086 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0086 0.0142
Toxoplasma gondii heat shock protein 75, putative 0.0029 0.0208 0.1328
Brugia malayi olfactory channel protein osm-9 0.0015 0.0026 0.0028
Schistosoma mansoni peroxidasin 0.004 0.0354 0.0344
Loa Loa (eye worm) blistered cuticle protein 3 0.004 0.0354 0.0671
Echinococcus multilocularis heat shock protein 90 0.007 0.0775 0.0768
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.3305 0.33
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0014 0.0011 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0086 0.0078
Echinococcus multilocularis Mastin 0.0019 0.0072 0.0064
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.011 0.0103
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0011 0.0004
Echinococcus granulosus two pore calcium channel protein 1 0.0014 0.0011 0.0004
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0011 0.0004
Echinococcus granulosus caspase 3 0.0158 0.1962 0.1956
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Brugia malayi hypothetical protein 0.003 0.0217 0.0391
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0405 0.5156
Brugia malayi Trypsin-like protease protein 5 0.0019 0.0072 0.0116
Brugia malayi Pre-SET motif family protein 0.0226 0.2896 0.5476
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0058 0.0599 0.3951
Echinococcus granulosus lamin 0.0029 0.0213 0.0206
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.01 0.1171
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.011 0.0477
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Echinococcus multilocularis endoplasmin 0.0056 0.0579 0.0572
Loa Loa (eye worm) calcium channel 0.0014 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0048 0.0254
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Loa Loa (eye worm) hypothetical protein 0.0058 0.0599 0.1134
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0308 0.0565
Schistosoma mansoni heat shock protein 0.007 0.0775 0.0765
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0028 0.0054
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0086 0.0078
Brugia malayi hypothetical protein 0.0022 0.011 0.0188
Echinococcus multilocularis caspase 3 0.0158 0.1962 0.1956
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0011 0.0004
Onchocerca volvulus 0.0031 0.0239 0.0434
Echinococcus multilocularis microtubule associated protein 2 0.0748 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0405 0.5156
Onchocerca volvulus 0.0043 0.0405 0.0748
Brugia malayi hypothetical protein 0.0022 0.011 0.0188
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Schistosoma mansoni coup transcription factor 0.002 0.0086 0.0075
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis heat shock protein 90 0.0056 0.0579 0.0572
Brugia malayi Cell death protein 3 precursor 0.0058 0.0599 0.1116
Schistosoma mansoni cpg binding protein 0.0033 0.0263 0.0253
Schistosoma mansoni sodium/chloride dependent transporter 0.0401 0.528 0.5275
Echinococcus granulosus heat shock protein 90 0.0056 0.0579 0.0572
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0011 0.0004
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.011 0.0103
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0011 0.0004
Echinococcus multilocularis voltage dependent calcium channel 0.0014 0.0011 0.0004
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.01 0.1573
Schistosoma mansoni thyroid hormone receptor 0.002 0.0086 0.0075
Loa Loa (eye worm) norepinephrine transporter 0.0401 0.528 1
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0011 0.0004
Echinococcus granulosus hypothetical protein 0.0014 0.0011 0.0004
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0043 0.0405 0.0766
Loa Loa (eye worm) hypothetical protein 0.0167 0.2088 0.3955
Plasmodium falciparum heat shock protein 90 0.007 0.0775 0.3677
Onchocerca volvulus 0.0401 0.528 1
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0043 0.0405 0.5156
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0346 0.0336
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0048 0.0495
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0014 0.0011 0.0004
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0297 0.1376
Brugia malayi CXXC zinc finger family protein 0.0031 0.0239 0.0434
Schistosoma mansoni sodium/chloride dependent transporter 0.0068 0.0743 0.0733
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0019 0.0072 0.0064
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Onchocerca volvulus 0.0019 0.0072 0.0116
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0086 0.0142
Brugia malayi nuclear hormone receptor 0.002 0.0086 0.0142
Mycobacterium ulcerans heat shock protein 90 0.0056 0.0579 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0011 0.0004
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0086 0.0075
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0014 0.0011 0.0004
Echinococcus granulosus transmembrane protease serine 3 0.0019 0.0072 0.0064
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0086 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0012 0.0014
Echinococcus granulosus enteropeptidase 0.0019 0.0072 0.0064
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0265 0.0255
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0014 0.0011 0.0004
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0297 0.3743
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0043 0.0405 0.0398
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Echinococcus granulosus lamin dm0 0.0029 0.0213 0.0206
Loa Loa (eye worm) voltage-gated calcium channel 0.0014 0.0011 0.002
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0029 0.0208 0.0952
Schistosoma mansoni hypothetical protein 0.0019 0.0072 0.0061
Echinococcus multilocularis lamin dm0 0.0029 0.0213 0.0206
Echinococcus multilocularis transient receptor potential cation channel 0.0015 0.0026 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0086 0.0162
Onchocerca volvulus 0.002 0.0086 0.0142
Echinococcus granulosus caspase 0.0215 0.2745 0.274
Schistosoma mansoni rab6-interacting 0.0022 0.011 0.0099
Entamoeba histolytica hypothetical protein 0.0039 0.0346 0.1615
Onchocerca volvulus 0.0019 0.0072 0.0116
Giardia lamblia Rab geranylgeranyltransferase 0.0167 0.2088 1
Brugia malayi heat shock protein 90 0.007 0.0775 0.145
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0775 1
Toxoplasma gondii heat shock protein 90, putative 0.007 0.0775 0.5133
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.139
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Onchocerca volvulus 0.0019 0.0072 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0086 0.0142
Loa Loa (eye worm) hypothetical protein 0.0096 0.1116 0.2113
Toxoplasma gondii Hsp90 domain-containing protein 0.0029 0.0208 0.1328
Leishmania major heat shock protein, putative 0.0029 0.0208 0.2588
Loa Loa (eye worm) hypothetical protein 0.0015 0.0026 0.0048
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis protein quaking 0.0029 0.0217 0.021
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0019 0.0072 0.0064
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0048 0.0092
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0167 0.2088 0.3955
Echinococcus granulosus cpg binding protein 0.0033 0.0263 0.0256
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Schistosoma mansoni heat shock protein 0.007 0.0775 0.0765
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Schistosoma mansoni caspase-7 (C14 family) 0.0058 0.0599 0.0589
Schistosoma mansoni lamin 0.0029 0.0213 0.0203
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0014 0.0011 0.0003
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0014 0.0011 0.0004
Trypanosoma brucei heat shock protein 84, putative 0.0029 0.0208 0.2588
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Schistosoma mansoni microtubule-associated protein tau 0.0748 1 1
Brugia malayi hypothetical protein 0.004 0.0354 0.0652
Plasmodium vivax heat shock protein 90, putative 0.0029 0.0208 0.0952
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0068 0.0743 1
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0029 0.0208 0.0375
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0014 0.0011 0.0004
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0579 0.1718
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0086 0.0162
Trichomonas vaginalis set domain proteins, putative 0.0258 0.332 1
Trypanosoma cruzi heat shock protein 90, putative 0.0042 0.0381 0.4855
Trypanosoma brucei Heat shock protein 83, putative 0.007 0.0775 1
Leishmania major DNA polymerase eta, putative 0.0049 0.0476 0.6091
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0086 0.0142
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0058 0.0599 0.0589
Toxoplasma gondii hypothetical protein 0.0043 0.0405 0.2647
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0014 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.0054 0.0545 0.1033
Loa Loa (eye worm) trypsin family protein 0.0019 0.0072 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Toxoplasma gondii hypothetical protein 0.0068 0.0743 0.492
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0014 0.0011 0.0003
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0086 0.0078
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0014 0.0011 0.0004
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.3305 0.33
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0011 0.0001
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Trichomonas vaginalis endoplasmin, putative 0.0043 0.0404 0.1188
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus voltage gated hydrogen channel 1 0.0014 0.0011 0.0004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0401 0.528 1
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0056 0.0579 0.0572
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Trypanosoma cruzi Heat shock protein 83, putative 0.007 0.0775 1
Schistosoma mansoni thyroid hormone receptor 0.002 0.0086 0.0075
Echinococcus granulosus caspase 2 0.0058 0.0599 0.0592
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0265 0.0258
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.01 0.1171
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0068 0.0743 0.139
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0527 0.098
Loa Loa (eye worm) hypothetical protein 0.0096 0.1116 0.2113
Echinococcus granulosus shaker cognate 0.0014 0.0011 0.0004
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0476 0.6091
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0011 0.002
Echinococcus granulosus potassium large conductance calcium activated 0.0014 0.0011 0.0004
Trypanosoma cruzi metacaspase, putative 0.0058 0.0599 0.7697
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0775 1
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0167 0.2088 0.2083
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Brugia malayi Trypsin family protein 0.0019 0.0072 0.0116
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0011 0.0004
Echinococcus granulosus serotonin transporter 0.0401 0.528 0.5276
Loa Loa (eye worm) hypothetical protein 0.0401 0.528 1
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.01 0.1171
Trichomonas vaginalis rotamase, putative 0.0036 0.0308 0.0899
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0167 0.2088 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.492
Echinococcus granulosus intermediate filament protein 0.0029 0.0213 0.0206
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0058 0.0599 0.1116
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0167 0.2088 0.6277
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0579 0.1718
Onchocerca volvulus Dual oxidase homolog 0.004 0.0354 0.0652
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0086 0.0142
Echinococcus granulosus peroxidasin 0.004 0.0354 0.0347
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0743 0.3524
Mycobacterium ulcerans hypothetical protein 0.0019 0.0072 0.1072
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0014 0.0011 0.0004
Brugia malayi hypothetical protein 0.0019 0.0072 0.0116
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0167 0.2088 1
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0056 0.0579 1
Echinococcus granulosus heat shock protein 0.007 0.0775 0.0768
Onchocerca volvulus 0.0068 0.0743 0.139
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0014 0.0011 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0011 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0086 0.0162
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0043 0.0405 0.1896
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0129 0.1577 0.1571
Schistosoma mansoni caspase-3 (C14 family) 0.0215 0.2745 0.2738
Echinococcus multilocularis musashi 0.0029 0.0213 0.0206
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.492
Schistosoma mansoni endoplasmin 0.007 0.0775 0.0765
Echinococcus multilocularis short transient receptor potential channel 6 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.01 0.017
Schistosoma mansoni hypothetical protein 0.0039 0.0346 0.0336
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0129 0.1577 0.1571
Loa Loa (eye worm) hypothetical protein 0.0049 0.0476 0.0902
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0019 0.0072 0.0116
Onchocerca volvulus Chorion peroxidase homolog 0.004 0.0354 0.0652
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0086 0.0162
Giardia lamblia Grp94/Hsp90 0.0056 0.0579 0.2737
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0012 0.0014
Schistosoma mansoni hypothetical protein 0.0029 0.0217 0.0206
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0029 0.0208 0.0201
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Schistosoma mansoni cpg binding protein 0.0031 0.0239 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0014
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0086 0.0078
Trypanosoma brucei DNA polymerase eta, putative 0.0049 0.0476 0.6091
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.028 0.352
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Onchocerca volvulus 0.0019 0.0072 0.0116
Echinococcus multilocularis RUN 0.0022 0.011 0.0103
Echinococcus multilocularis lamin 0.0029 0.0213 0.0206
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0086 0.0078
Entamoeba histolytica hypothetical protein 0.0039 0.0346 0.1615
Schistosoma mansoni survival motor neuron protein 0.0052 0.0527 0.0517
Schistosoma mansoni sodium/chloride dependent transporter 0.0068 0.0743 0.0733
Brugia malayi Doublecortin family protein 0.0022 0.011 0.0188
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0011 0.002
Trypanosoma brucei metacaspase 5, putative 0.0058 0.0599 0.7697
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0405 0.5156
Onchocerca volvulus 0.0022 0.011 0.0188
Echinococcus multilocularis expressed protein 0.0036 0.0308 0.0301
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0043 0.0405 0.0398
Onchocerca volvulus 0.0029 0.0213 0.0385
Entamoeba histolytica heat shock protein 90, putative 0.007 0.0775 0.3677
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0297 0.1921
Trypanosoma cruzi metacaspase, putative 0.0058 0.0599 0.7697
Trypanosoma brucei metacaspase MCA3 0.0058 0.0599 0.7697
Echinococcus granulosus short transient receptor potential channel 6 0.0014 0.0011 0.0004
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0086 0.0078
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0068 0.0743 0.0736
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0014 0.0011 0.0003
Schistosoma mansoni caspase-7 (C14 family) 0.0215 0.2745 0.2738
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.011 0.0103
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0011 0.0001
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0354 0.0671
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Schistosoma mansoni hypothetical protein 0.0052 0.0527 0.0517
Brugia malayi hypothetical protein 0.0039 0.0346 0.0637
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0058 0.0599 0.3951
Schistosoma mansoni loxhd1 0.0022 0.011 0.0099
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0022 0.011 0.0208
Echinococcus multilocularis transient receptor potential cation channel 0.0015 0.0026 0.0018
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0011 0.0004
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0213 0.0404
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Onchocerca volvulus 0.0029 0.0213 0.0385
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0011 0.0004
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Echinococcus multilocularis cpg binding protein 0.0033 0.0263 0.0256
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Trypanosoma cruzi heat shock protein, putative 0.0029 0.0208 0.2588
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0014 0.0011 0.0003
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.2896 0.5485
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0048 0.0495
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Schistosoma mansoni peroxidasin 0.004 0.0354 0.0344
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Echinococcus granulosus sodium and chloride dependent glycine 0.0068 0.0743 0.0736
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0068 0.0743 0.0736
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Onchocerca volvulus 0.0068 0.0743 0.139
Echinococcus multilocularis transfer RNA-Gly 0.0014 0.0011 0.0004
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.011 0.0477
Echinococcus granulosus expressed protein 0.0036 0.0308 0.0301
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0022 0.011 0.0208
Onchocerca volvulus Cell death protein 3 homolog 0.0058 0.0599 0.1116
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Schistosoma mansoni rab6-interacting 0.0022 0.011 0.0099
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0086 0.0078
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Echinococcus granulosus endoplasmin 0.0056 0.0579 0.0572
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0265 0.0258
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Echinococcus granulosus protein quaking 0.0029 0.0217 0.021
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0354 0.0671
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.01 0.0093
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0048 0.0182
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0401 0.528 0.5275
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Brugia malayi Pre-SET motif family protein 0.0033 0.0265 0.0483
Plasmodium vivax amine transporter, putative 0.0068 0.0743 0.3524
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0297 0.3743
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0086 0.0142
Plasmodium vivax heat shock protein, putative 0.0029 0.0208 0.0952
Echinococcus multilocularis two pore calcium channel protein 1 0.0014 0.0011 0.0004
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.1407
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0043 0.0405 0.0748
Trypanosoma brucei unspecified product 0.0014 0.0012 0.0014
Giardia lamblia DINP protein human, muc B family 0.0021 0.01 0.043
Echinococcus granulosus Mastin 0.0019 0.0072 0.0064
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.01 0.0189
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Plasmodium falciparum transporter, putative 0.0068 0.0743 0.3524
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0048 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0086 0.0142
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0048 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Echinococcus multilocularis tumor protein p63 0.0366 0.4802 0.4798
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0476 0.0883
Echinococcus multilocularis transient receptor potential gamma protein 0.0014 0.0011 0.0004
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0014 0.0011 0.0003
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0048 0.0254
Brugia malayi Blistered cuticle protein 3 0.004 0.0354 0.0652
Brugia malayi Trypsin family protein 0.0019 0.0072 0.0116
Leishmania major DNA polymerase eta, putative 0.0034 0.028 0.352
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0167 0.2088 0.3943
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0014 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Brugia malayi intermediate filament protein 0.0029 0.0213 0.0385
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0011 0.0004
Echinococcus multilocularis sodium and chloride dependent glycine 0.0068 0.0743 0.0736
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0599 0.283
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.119
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0297 0.3743
Schistosoma mansoni sodium-dependent amino acid transporter 0.0068 0.0743 0.0733
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0014 0.0011 0.0004
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0086 0.0078
Echinococcus granulosus dna polymerase eta 0.0049 0.0476 0.0469
Schistosoma mansoni endoplasmin 0.007 0.0775 0.0765
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0011 0.0004
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0011 0.002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.01 0.027
Echinococcus multilocularis transmembrane protease serine 3 0.0019 0.0072 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Schistosoma mansoni lipoxygenase 0.0091 0.1047 0.1038
Brugia malayi hypothetical protein 0.0256 0.3305 0.6253
Echinococcus granulosus voltage dependent calcium channel 0.0014 0.0011 0.0004
Loa Loa (eye worm) ryanodine receptor 0.0014 0.0011 0.002
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0011 0.0004
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0043 0.0405 0.1896
Schistosoma mansoni DNA polymerase eta 0.0049 0.0476 0.0466
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.01 0.1171
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0213 0.0385
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.1407
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0043 0.0405 0.5156
Toxoplasma gondii hypothetical protein 0.0124 0.1499 1
Onchocerca volvulus Peroxidasin homolog 0.004 0.0354 0.0652
Trypanosoma brucei unspecified product 0.0021 0.01 0.1171
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0167 0.2088 0.6277
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0068 0.0743 0.0736
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0086 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.5156
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0011 0.0001
Plasmodium vivax metacaspase 1, putative 0.0058 0.0599 0.283
Echinococcus granulosus heat shock protein 90 0.007 0.0775 0.0768
Loa Loa (eye worm) hypothetical protein 0.0033 0.0265 0.0502
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0011 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0011 0.0001
Giardia lamblia Rab geranylgeranyltransferase 0.0043 0.0405 0.1896
Plasmodium falciparum metacaspase-like protein 0.0058 0.0599 0.283
Trypanosoma brucei Metacaspase-4 0.0058 0.0599 0.7697
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0048 0.0041
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Echinococcus granulosus sodium channel protein 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0086 0.0142
Toxoplasma gondii heat shock protein HSP90 0.007 0.0775 0.5133
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0086 0.0142
Onchocerca volvulus Peroxidase homolog 0.004 0.0354 0.0652
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0634 0.4191
Loa Loa (eye worm) voltage-dependent calcium channel 0.0014 0.0011 0.002
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0048 0.0041
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0048 0.0041
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0014 0.0011 0.0004
Treponema pallidum sodium- and chloride- dependent transporter 0.0401 0.528 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0265 0.171
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Entamoeba histolytica hypothetical protein 0.0039 0.0346 0.1615
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0086 0.0142
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0579 0.1718
Echinococcus multilocularis enteropeptidase 0.0019 0.0072 0.0064
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0011 0.0004
Schistosoma mansoni polycystin 1-related 0.0022 0.011 0.0099
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.139
Echinococcus multilocularis short transient receptor potential channel 6 0.0015 0.0026 0.0018
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Giardia lamblia Heat shock protein HSP 90-alpha 0.007 0.0775 0.3677
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0048 0.0495
Brugia malayi Temporarily assigned gene name protein 44 0.003 0.0217 0.0391
Echinococcus granulosus calcium activated potassium channel 0.0014 0.0011 0.0004
Trypanosoma brucei metacaspase 0.0058 0.0599 0.7697
Schistosoma mansoni lipoxygenase 0.0129 0.1577 0.1569
Echinococcus granulosus transient receptor potential gamma protein 0.0014 0.0011 0.0004
Brugia malayi hypothetical protein 0.0108 0.1284 0.2417
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0068 0.0743 0.0736
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0011 0.0001
Onchocerca volvulus Huntingtin homolog 0.0108 0.1284 0.2417
Leishmania major hypothetical protein, conserved 0.0014 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.492
Echinococcus granulosus two pore calcium channel protein 2 0.0014 0.0011 0.0004
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.011 0.0103
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0086 0.0075
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0265 0.0258
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0056 0.0579 1
Onchocerca volvulus Peroxidase homolog 0.004 0.0354 0.0652
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Schistosoma mansoni heat shock protein 0.0029 0.0208 0.0198
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0048 0.0041
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Loa Loa (eye worm) doublecortin family protein 0.0022 0.011 0.0208
Brugia malayi ecdysteroid receptor 0.002 0.0086 0.0142
Echinococcus multilocularis glycoprotein Antigen 5 0.0019 0.0072 0.0064
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.01 0.009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Echinococcus multilocularis calcium activated potassium channel 0.0014 0.0011 0.0004
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0043 0.0405 0.0398
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0028 0.0034
Echinococcus multilocularis caspase 0.0215 0.2745 0.274
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Echinococcus granulosus dnaJ subfamily B 0.0444 0.5852 0.5849
Loa Loa (eye worm) hypothetical protein 0.0108 0.1284 0.2433
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.5156
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0167 0.2088 1
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0215 0.2745 0.274
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0354 0.0671
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0056 0.0579 1
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Schistosoma mansoni eyes absent homolog 0.0096 0.1116 0.1106
Loa Loa (eye worm) solute carrier family 6 member 4 0.0401 0.528 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0308 0.0584
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.011 0.0103
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Loa Loa (eye worm) hypothetical protein 0.0068 0.0743 0.1407
Echinococcus granulosus ryanodine receptor 44f 0.0014 0.0011 0.0004
Schistosoma mansoni nuclear hormone receptor 0.002 0.0086 0.0075
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0048 0.0041
Echinococcus multilocularis voltage dependent calcium channel 0.0014 0.0011 0.0004
Echinococcus multilocularis dna polymerase kappa 0.0021 0.01 0.0093
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0014 0.0011 0.0003
Schistosoma mansoni rotamase 0.0036 0.0308 0.0298
Echinococcus granulosus dna polymerase kappa 0.0021 0.01 0.0093
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.01 0.043
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0208 0.0597
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.01 0.1171
Schistosoma mansoni intermediate filament proteins 0.0029 0.0213 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Loa Loa (eye worm) heat shock protein 90 0.007 0.0775 0.1467
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0135
Schistosoma mansoni hypothetical protein 0.0019 0.0072 0.0061
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0014 0.0011 0.0004
Echinococcus granulosus transient receptor potential cation channel 0.0015 0.0026 0.0018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0213 0.0404
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Trypanosoma brucei metacaspase MCA2 0.0058 0.0599 0.7697
Echinococcus granulosus hypothetical protein 0.0029 0.0217 0.021
Toxoplasma gondii hypothetical protein 0.0068 0.0743 0.492
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0086 0.0075
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0167 0.2088 0.2083
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0599 0.1777
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0068 0.0743 0.0733
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0072 0.0061
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0048 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0545 0.0535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0086 0.0162
Brugia malayi hypothetical protein 0.0068 0.0743 0.139
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0014 0.0011 0.0004
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0011 0.0004
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.5156
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0086 0.0075
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0068 0.0743 0.139
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0043 0.0405 0.1896
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0671
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus multilocularis shaker cognate 0.0014 0.0011 0.0004
Echinococcus granulosus caspase 8 0.0058 0.0599 0.0592
Onchocerca volvulus 0.004 0.0354 0.0652
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0014 0.0011 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0265 0.0255
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0048 0.0072
Brugia malayi nuclear receptor NHR-88 0.002 0.0086 0.0142
Echinococcus granulosus FTZ F1 alpha 0.002 0.0086 0.0078
Plasmodium falciparum amino acid transporter, putative 0.0068 0.0743 0.3524
Brugia malayi Animal haem peroxidase family protein 0.004 0.0354 0.0652
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.01 0.1573
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0014 0.0011 0.0004
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0043 0.0405 0.5156
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0167 0.2088 0.208
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0011 0.0004
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0297 0.3743
Echinococcus multilocularis two pore calcium channel protein 2 0.0014 0.0011 0.0004
Trypanosoma brucei heat shock protein, putative 0.007 0.0775 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0011 0.0001
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0029 0.0208 0.0201
Brugia malayi Trypsin family protein 0.0019 0.0072 0.0116
Trypanosoma cruzi heat shock protein 85, putative 0.0056 0.0579 0.7443
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0086 0.0162
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.01 0.1171
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0014 0.0011 0.0004
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0064
Trypanosoma cruzi metacaspase 5, putative 0.0058 0.0599 0.7697
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0086 0.0078
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0265 0.0255
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0162
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0064 0.0689 0.0679
Loa Loa (eye worm) tumor suppressor 0.0349 0.4562 0.864
Echinococcus multilocularis caspase 8 0.0058 0.0599 0.0592
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.01 0.1573
Onchocerca volvulus 0.0054 0.0545 0.1014
Plasmodium falciparum metacaspase 1 0.0058 0.0599 0.283
Echinococcus multilocularis dna polymerase eta 0.0049 0.0476 0.0469
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0308 0.0899
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.002
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0048 0.0664
Leishmania major heat shock protein 83-1 0.007 0.0775 1
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0014 0.0011 0.0003
Onchocerca volvulus 0.0052 0.0527 0.098
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.01 0.1171
Trypanosoma brucei heat shock protein 90, putative 0.007 0.0775 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0068 0.0743 0.0736
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.0208 0.0952
Echinococcus multilocularis sodium leak channel non selective protein 0.0014 0.0011 0.0004
Leishmania major hypothetical protein, unknown function 0.0014 0.0011 0.0003
Schistosoma mansoni lamin 0.0029 0.0213 0.0203
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0014 0.0011 0.0004
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0014 0.0011 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0599 0.1777
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0086 0.0075
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.01 0.1171
Loa Loa (eye worm) endoplasmin 0.007 0.0775 0.1467
Loa Loa (eye worm) hypothetical protein 0.0058 0.0599 0.1134
Echinococcus granulosus glycoprotein Antigen 5 0.0019 0.0072 0.0064
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.011 0.0103
Echinococcus granulosus tumor protein p63 0.0366 0.4802 0.4798
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0086 0.0078
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.01 0.0093
Loa Loa (eye worm) heat shock protein 75 0.0029 0.0208 0.0395
Loa Loa (eye worm) hypothetical protein 0.003 0.0217 0.0411
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0072 0.0061
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0346 0.0339
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0014 0.0011 0.0004
Trypanosoma cruzi metacaspase, putative 0.0058 0.0599 0.7697
Trypanosoma cruzi metacaspase, putative 0.0058 0.0599 0.7697

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 218 nM Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane. ChEMBL. 12213054
IC50 (binding) = 218 nM Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane. ChEMBL. 12213054
Ratio (functional) = 0.2 Ratio of the IC50 value of Mazindol to that of the compound in guinea pig was determined ChEMBL. 12213054
Ratio (functional) = 0.2 Ratio of the IC50 value of Mazindol to that of the compound in guinea pig was determined ChEMBL. 12213054

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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