Detailed information for compound 266239

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 294.343 | Formula: C16H22O5
  • H donors: 4 H acceptors: 5 LogP: -0.8 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC1=C[C@@H]2CCCCC3([C@@]([C@@H]1O)(O)[C@@H](O)C(=C3)C)C2=O
  • InChi: 1S/C16H22O5/c1-9-7-15-5-3-2-4-10(13(15)19)6-11(8-17)14(20)16(15,21)12(9)18/h6-7,10,12,14,17-18,20-21H,2-5,8H2,1H3/t10-,12-,14+,15?,16+/m0/s1
  • InChiKey: UTCUJQPIIDWICV-OYWLMEGYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0104 0.0108
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0374 0.0405
Brugia malayi tubulin alpha-2 chain 0.073 0.9104 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0104 0.0069
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0104 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0235 0.0252
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0374 0.0374
Loa Loa (eye worm) RecQ helicase 0.0021 0.0166 0.0176
Echinococcus multilocularis pyruvate kinase 0.0017 0.0113 0.0113
Echinococcus granulosus tubulin alpha chain 0.073 0.9104 1
Echinococcus multilocularis tubulin subunit beta 0.0597 0.742 0.742
Leishmania major alpha tubulin 0.073 0.9104 1
Schistosoma mansoni biogenic amine receptor 0.0038 0.0374 0.0411
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0666 0.0731
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0374 0.0374
Giardia lamblia Beta tubulin 0.0597 0.742 0.8148
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0316 0.034
Schistosoma mansoni apoferritin-2 0.0008 0.0006 0.0006
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0104 0.0429
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0104 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0104 0.0104
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0078 0.0079
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0127 0.0129
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0349 0.0377
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.046 0.0499
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0316 0.034
Mycobacterium leprae cell division protein FtsZ 0.0191 0.2304 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0374 0.0374
Trichomonas vaginalis tubulin gamma chain, putative 0.0439 0.5437 0.5969
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.1244 0.5386
Leishmania major beta tubulin 0.0597 0.742 0.8141
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0374 0.0411
Echinococcus granulosus serotonin receptor 0.0038 0.0374 0.0411
Onchocerca volvulus 0.0038 0.0374 0.1214
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0279 0.0307
Echinococcus granulosus pyruvate kinase 0.0033 0.0316 0.0347
Echinococcus granulosus Tubulin beta 2C chain 0.0597 0.742 0.815
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.1244 0.5386
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0058 0.0057
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0374 0.0411
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0266 0.0286
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0374 0.0411
Schistosoma mansoni ferritin light chain 0.0008 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0202 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.046 0.0499
Loa Loa (eye worm) tubulin alpha 2 0.0539 0.67 0.7358
Brugia malayi PAS domain containing protein 0.0048 0.0506 0.055
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1254 0.1372
Loa Loa (eye worm) tubulin beta-1 chain 0.0597 0.742 0.8148
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0374 0.0405
Echinococcus granulosus tubulin alpha chain 0.073 0.9104 1
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0374 0.0411
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0374 0.0374
Trypanosoma cruzi epsilon tubulin, putative 0.0439 0.5437 0.5969
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0166 0.0176
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0134 0.0136
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Leishmania major beta tubulin 0.0597 0.742 0.8141
Echinococcus granulosus Tubulin beta 2C chain 0.0597 0.742 0.815
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0316 0.034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0202 0.0216
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0346 0.0373
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0374 0.0405
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0374 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0453 0.0498
Echinococcus multilocularis beta tubulin 0.0597 0.742 0.742
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0374 0.0374
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0374 0.0405
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0088 0.005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0165 0.0175
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0666 0.0725
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.046 0.0499
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0615 0.0615
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0374 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.046 0.0499
Schistosoma mansoni opsin-like receptor 0.0038 0.0374 0.0411
Onchocerca volvulus 0.0038 0.0374 0.1214
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0374 0.0405
Echinococcus granulosus pyruvate kinase 0.0033 0.0316 0.0347
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0088 0.009
Schistosoma mansoni neuropeptide receptor 0.0038 0.0374 0.0411
Brugia malayi Thioredoxin reductase 0.0047 0.0489 0.0531
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0127 0.0134
Treponema pallidum cell division protein FtsZ 0.0191 0.2304 1
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1254 0.1372
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0453 0.0453
Schistosoma mansoni amine GPCR 0.0038 0.0374 0.0411
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0374 0.0411
Brugia malayi Dopamine receptor 0.0038 0.0374 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0166 0.0166
Schistosoma mansoni single-minded 0.0048 0.0506 0.0556
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0021 0.0023
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.1393 0.6038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0374 0.0374
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0374 0.0411
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trypanosoma cruzi tubulin delta chain 0.0191 0.2304 0.2526
Echinococcus granulosus tubulin alpha 0.0439 0.5437 0.5972
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.003 0.0279 0.0301
Echinococcus granulosus intermediate filament protein 0.0027 0.0236 0.0259
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0374 0.0411
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0104 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0263 0.0283
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.046 0.0461
Loa Loa (eye worm) hypothetical protein 0.0033 0.0312 0.0336
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0091 0.0091
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0316 0.0341
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0374 0.0374
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0615 0.0669
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0374 0.0411
Echinococcus multilocularis tubulin subunit TubB 0.073 0.9104 0.9104
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0374 0.0411
Loa Loa (eye worm) hypothetical protein 0.0539 0.67 0.7358
Echinococcus granulosus somatostatin receptor 0.0038 0.0374 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Echinococcus multilocularis tubulin gamma 1 chain 0.0439 0.5437 0.5437
Schistosoma mansoni hypothetical protein 0.0038 0.0374 0.0411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0345 0.0373
Echinococcus multilocularis pyruvate kinase 0.0017 0.0113 0.0113
Schistosoma mansoni tubulin subunit gamma 0.0439 0.5437 0.5972
Schistosoma mansoni neuropeptide receptor 0.0038 0.0374 0.0411
Onchocerca volvulus 0.0012 0.0058 0.0167
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.046 0.046
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0374 0.0405
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0374 0.0411
Leishmania major beta tubulin 0.0597 0.742 0.8141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0345 0.0373
Schistosoma mansoni pyruvate kinase 0.0017 0.0113 0.0124
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.005 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0378 0.0409
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0489 0.0537
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0091 0.0093
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0489 0.0531
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0374 0.0411
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0374 0.0411
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0374 0.0411
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0127 0.053
Onchocerca volvulus 0.0038 0.0374 0.1214
Echinococcus multilocularis tubulin alpha 1C chain 0.073 0.9104 0.9104
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0266 0.0286
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0012 0.0058 0.0057
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0247 0.0265
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0316 0.034
Brugia malayi hypothetical protein 0.012 0.1416 0.155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0235 0.0252
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.1254 0.5431
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.065 0.0714
Brugia malayi Melatonin receptor type 1A 0.0038 0.0374 0.0405
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0266 0.8073
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0316 0.034
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0127 0.0127
Trichomonas vaginalis tubulin alpha chain, putative 0.0249 0.3033 0.3327
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.046 0.0499
Trypanosoma cruzi zeta tubulin, putative 0.0191 0.2304 0.2526
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0088 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Echinococcus multilocularis beta tubulin 0.0597 0.742 0.742
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.008 0.0081
Mycobacterium tuberculosis Possible hydrolase 0.0008 0.0007 0.0006
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0266 0.0285
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0346 0.0335
Schistosoma mansoni hypothetical protein 0.0015 0.0091 0.01
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0266 0.0286
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0127 0.0134
Schistosoma mansoni biogenic amine receptor 0.0038 0.0374 0.0411
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0127 0.053
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0021 0.0021
Echinococcus multilocularis geminin 0.0167 0.2011 0.2011
Brugia malayi Dopamine receptor protein 1 0.0038 0.0374 0.0405
Mycobacterium ulcerans arylsulfatase, AslA 0.0008 0.0007 0.0006
Brugia malayi 6-phosphofructokinase 0.0107 0.1254 0.1372
Echinococcus granulosus tubulin subunit TubB 0.073 0.9104 1
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0316 0.034
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1254 0.1372
Schistosoma mansoni ap endonuclease 0.0018 0.0127 0.014
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0266 0.0286
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0104 0.0069
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0615 0.0675
Echinococcus granulosus cpg binding protein 0.0029 0.0267 0.0293
Leishmania major beta tubulin 0.0597 0.742 0.8141
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0236 0.0253
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Leishmania major beta tubulin 0.0597 0.742 0.8141
Schistosoma mansoni tubulin subunit alpha 0.0191 0.2304 0.2531
Plasmodium falciparum tubulin beta chain 0.0597 0.742 0.8148
Trypanosoma brucei epsilon tubulin 0.0439 0.5437 0.5969
Schistosoma mansoni hypothetical protein 0.0051 0.0544 0.0598
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0539 0.67 0.7358
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0374 0.0411
Echinococcus multilocularis expressed protein 0.0008 0.0006 0.0006
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0091 0.01
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0374 0.0374
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0374 0.0374
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0374 0.0374
Echinococcus multilocularis lamin 0.0027 0.0236 0.0236
Trichomonas vaginalis tubulin alpha chain, putative 0.0439 0.5437 0.5969
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0091 0.0091
Schistosoma mansoni opsin-like receptor 0.0038 0.0374 0.0411
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Mycobacterium ulcerans arylsulfatase AtsB 0.0008 0.0007 0.0006
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1254 0.1377
Trypanosoma brucei beta tubulin 0.0439 0.5437 0.5969
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0266 0.0282
Echinococcus multilocularis serotonin receptor 0.0038 0.0374 0.0374
Loa Loa (eye worm) BEN-1 protein 0.0597 0.742 0.8148
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0374 0.0411
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0374 0.0374
Echinococcus granulosus g protein coupled receptor 0.0038 0.0374 0.0411
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.046 0.0505
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0374 0.0374
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.001 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0374 0.0411
Schistosoma mansoni hypothetical protein 0.0015 0.0091 0.01
Plasmodium vivax glutathione reductase, putative 0.0047 0.0489 0.0453
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.046 0.0499
Schistosoma mansoni myosin xvIII 0.0038 0.0374 0.0411
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0104 0.0108
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0316 0.034
Toxoplasma gondii alpha-tubulin I, putative 0.073 0.9104 1
Trypanosoma brucei beta tubulin 0.0597 0.742 0.8148
Trichomonas vaginalis tubulin beta chain, putative 0.073 0.9104 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0058 0.0057
Onchocerca volvulus 0.0038 0.0374 0.1214
Trichomonas vaginalis tubulin alpha chain, putative 0.0597 0.742 0.8148
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.1244 0.5386
Trypanosoma cruzi zeta tubulin, putative 0.0191 0.2304 0.2526
Plasmodium falciparum glutathione reductase 0.0016 0.0104 0.0104
Echinococcus multilocularis Tubulin alpha 1 chain 0.073 0.9104 0.9104
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0374 0.0374
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0374 0.0411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0235 0.0252
Loa Loa (eye worm) beta-tubulin 0.0597 0.742 0.8148
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0503 0.0546
Leishmania major alpha tubulin 0.073 0.9104 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0127 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0453 0.0498
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0018 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0104 0.0108
Echinococcus multilocularis tubulin delta chain 0.0191 0.2304 0.2304
Leishmania major trypanothione reductase 0.0047 0.0489 0.0493
Schistosoma mansoni hypothetical protein 0.0015 0.0091 0.01
Brugia malayi CXXC zinc finger family protein 0.0028 0.0247 0.0265
Loa Loa (eye worm) tubulin beta-2A chain 0.0597 0.742 0.8148
Loa Loa (eye worm) hypoxia-induced factor 1 0.0149 0.1775 0.1945
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0316 0.0341
Onchocerca volvulus 0.0038 0.0374 0.1214
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0374 0.0405
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0088 0.009
Trichomonas vaginalis tubulin epsilon chain, putative 0.0191 0.2304 0.2526
Trichomonas vaginalis tubulin epsilon chain, putative 0.0597 0.742 0.8148
Schistosoma mansoni adenoreceptor 0.0038 0.0374 0.0411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0316 0.0341
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0191 0.2304 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0316 0.0341
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0374 0.0374
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0058 0.0017
Brugia malayi Tubulin gamma chain 0.0439 0.5437 0.5969
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0088 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0279 0.0307
Mycobacterium tuberculosis Cell division protein FtsZ 0.0191 0.2304 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0374 0.0411
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0012 0.0058 0.0057
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0042 0.004
Loa Loa (eye worm) alpha-tubulin 0.073 0.9104 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1254 0.1372
Echinococcus multilocularis serotonin receptor 0.0038 0.0374 0.0374
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0489 0.2103
Trichomonas vaginalis tubulin beta chain, putative 0.073 0.9104 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0104 0.0108
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.002 0.0015
Echinococcus granulosus pyruvate kinase 0.0017 0.0113 0.0124
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.001 0.001
Plasmodium falciparum tubulin delta chain, putative 0.0191 0.2304 0.2523
Trichomonas vaginalis tubulin beta chain, putative 0.073 0.9104 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0104 0.0108
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0009 0.0018 0.0013
Onchocerca volvulus 0.0038 0.0374 0.1214
Brugia malayi glutathione reductase 0.0047 0.0489 0.0531
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0374 0.0411
Echinococcus granulosus expressed protein 0.0008 0.0006 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0104 0.0108
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0279 0.0307
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0316 0.102
Onchocerca volvulus 0.0038 0.0374 0.1214
Entamoeba histolytica tubulin family protein 0.0597 0.742 0.8148
Leishmania major beta tubulin 0.0597 0.742 0.8141
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0374 0.0411
Echinococcus multilocularis Tubulin alpha 1 chain 0.073 0.9104 0.9104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0316 0.0341
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0316 0.102
Echinococcus multilocularis tubulin alpha chain 0.073 0.9104 0.9104
Trypanosoma brucei beta tubulin 0.0597 0.742 0.8148
Schistosoma mansoni cpg binding protein 0.0028 0.0247 0.0272
Echinococcus granulosus allatostatin A receptor 0.0038 0.0374 0.0411
Leishmania major alpha tubulin 0.073 0.9104 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0316 0.034
Echinococcus granulosus alpha tubulin 0.073 0.9104 1
Plasmodium vivax tubulin beta chain, putative 0.0597 0.742 0.8133
Echinococcus granulosus GPCR family 2 0.0015 0.0091 0.01
Plasmodium vivax tubulin epsilon chain, putative 0.0439 0.5437 0.5936
Echinococcus granulosus tubulin alpha 3 chain 0.073 0.9104 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.1393 0.6038
Giardia lamblia Pyruvate kinase 0.0017 0.0113 0.0117
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0266 0.0206
Schistosoma mansoni tubulin subunit beta 0.0191 0.2304 0.2531
Giardia lamblia GTOR 0.0044 0.046 0.0498
Echinococcus granulosus neuropeptide receptor 0.0038 0.0374 0.0411
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.1254 0.1377
Echinococcus granulosus sex peptide receptor 0.0038 0.0374 0.0411
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.019 0.0202
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.1254 0.1254
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Schistosoma mansoni fkbp-rapamycin associated protein 0.0008 0.0006 0.0007
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.046 0.0505
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0374 0.0405
Echinococcus multilocularis tubulin alpha chain 0.073 0.9104 0.9104
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0666 0.0731
Loa Loa (eye worm) hypothetical protein 0.0012 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Echinococcus granulosus tubulin beta 1 chain 0.0597 0.742 0.815
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0374 0.0374
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0104 0.0108
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0127 0.0134
Schistosoma mansoni hypothetical protein 0.0038 0.0374 0.0411
Onchocerca volvulus 0.0038 0.0374 0.1214
Trypanosoma cruzi alpha tubulin, putative 0.073 0.9104 1
Giardia lamblia Alpha-tubulin 0.073 0.9104 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Brugia malayi beta-tubulin, identical 0.0597 0.742 0.8148
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0374 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0058 0.0057
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0104 0.0108
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0008 0.0006 0.0007
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0008 0.0007 0.0001
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.1254 0.5431
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0276 0.0297
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.046 0.0499
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0374 0.0405
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0316 0.0261
Trichomonas vaginalis tubulin gamma chain, putative 0.0191 0.2304 0.2526
Plasmodium vivax SET domain protein, putative 0.003 0.0279 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Leishmania major beta tubulin 0.0597 0.742 0.8141
Brugia malayi Tubulin beta-1 chain 0.0597 0.742 0.8148
Echinococcus multilocularis serine protein kinase ATM 0.0008 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0001
Schistosoma mansoni tubulin subunit delta 0.0191 0.2304 0.2531
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0316 0.1348
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0191 0.2304 0.2526
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0374 0.0411
Brugia malayi 6-phosphofructokinase 0.0107 0.1254 0.1372
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.005 0.0048
Echinococcus granulosus beta tubulin 0.0597 0.742 0.815
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0539 0.67 0.7358
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0374 0.0411
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0316 0.1348
Schistosoma mansoni intermediate filament proteins 0.0027 0.0236 0.0259
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0058 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0374 0.0411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0202 0.0216
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0374 0.0374
Echinococcus multilocularis tubulin alpha chain 0.073 0.9104 0.9104
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0012 0.0058 0.0057
Loa Loa (eye worm) tubulin alpha 2 0.0539 0.67 0.7358
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0374 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0489 0.0531
Brugia malayi RNA binding protein 0.0061 0.0666 0.0725
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0489 0.0453
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0374 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0191 0.2304 0.2526
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0266 0.0286
Echinococcus granulosus tubulin delta chain 0.0191 0.2304 0.2531
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0439 0.5437 0.5969
Plasmodium vivax tubulin gamma chain, putative 0.0439 0.5437 0.5936
Leishmania major epsilon tubulin, putative 0.0439 0.5437 0.5953
Loa Loa (eye worm) glutathione reductase 0.0047 0.0489 0.0531
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0374 0.0405
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.008 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0345 0.0373
Plasmodium falciparum glutathione reductase 0.0047 0.0489 0.0527
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0104 0.0108
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0666 0.0725
Echinococcus multilocularis Tubulin beta 2C chain 0.0597 0.742 0.742
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0374 0.0374
Echinococcus granulosus tubulin alpha chain 0.073 0.9104 1
Leishmania major beta tubulin 0.0597 0.742 0.8141
Giardia lamblia Pyruvate kinase 0.0033 0.0316 0.0339
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0104 0.0429
Schistosoma mansoni tubulin subunit beta 0.0597 0.742 0.815
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0113 0.0118
Brugia malayi tubulin alpha chain - mouse 0.073 0.9104 1
Trypanosoma brucei zeta tubulin 0.0191 0.2304 0.2526
Leishmania major alpha tubulin 0.073 0.9104 1
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0349 0.0349
Leishmania major beta tubulin 0.0597 0.742 0.8141
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0374 0.0411
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0374 0.0411
Echinococcus multilocularis musashi 0.0027 0.0236 0.0236
Echinococcus granulosus g protein coupled receptor 0.0038 0.0374 0.0411
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0374 0.0405
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0489 0.0489
Schistosoma mansoni neuropeptide receptor 0.0038 0.0374 0.0411
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0374 0.0411
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.046 0.0461
Trichomonas vaginalis tubulin epsilon chain, putative 0.073 0.9104 1
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1254 0.1372
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0345 0.0373
Echinococcus granulosus orexin receptor type 2 0.0038 0.0374 0.0411
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0503 0.0546
Plasmodium falciparum alpha tubulin 2 0.073 0.9104 1
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0374 0.0374
Onchocerca volvulus 0.0038 0.0374 0.1214
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Brugia malayi hypothetical protein 0.0161 0.1933 0.2118
Trypanosoma brucei zeta tubulin, putative 0.0191 0.2304 0.2526
Echinococcus multilocularis tubulin alpha 1C chain 0.073 0.9104 0.9104
Loa Loa (eye worm) hypothetical protein 0.0017 0.0112 0.0117
Mycobacterium ulcerans arylsulfatase AtsD 0.0008 0.0007 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0374 0.0411
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.0374 0.0405
Loa Loa (eye worm) tubulin beta chain 0.0191 0.2304 0.2526
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0266 0.0286
Brugia malayi Pre-SET motif family protein 0.003 0.0279 0.0301
Loa Loa (eye worm) hypothetical protein 0.0015 0.0091 0.0093
Mycobacterium tuberculosis Probable sulfatase 0.0008 0.0007 0.0006
Schistosoma mansoni tubulin subunit alpha 0.073 0.9104 1
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0266 0.0286
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Brugia malayi neuropeptide F receptor 0.0038 0.0374 0.0405
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.001 0.001
Giardia lamblia Epsilon tubulin 0.0191 0.2304 0.2525
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0104 0.0108
Schistosoma mansoni ferritin 0.0008 0.0006 0.0006
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0374 0.0374
Loa Loa (eye worm) BEN-1 protein 0.0597 0.742 0.8148
Trypanosoma brucei epsilon tubulin 0.0439 0.5437 0.5969
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0104 0.0104
Loa Loa (eye worm) tubulin beta chain 0.0597 0.742 0.8148
Mycobacterium ulcerans hydrolase 0.0008 0.0007 0.0006
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1254 0.1372
Mycobacterium leprae Possible regulatory protein 0.0012 0.0058 0.0226
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0374 0.0374
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1254 0.1372
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0374 0.0411
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trichomonas vaginalis set domain proteins, putative 0.0235 0.2858 0.3135
Echinococcus granulosus tubulin gamma 1 chain 0.0439 0.5437 0.5972
Brugia malayi hypoxia-induced factor 1 0.0149 0.1775 0.1945
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0202 0.0216
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0104 0.0429
Loa Loa (eye worm) hypothetical protein 0.0482 0.5972 0.6557
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0058 0.0057
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0042 0.004
Loa Loa (eye worm) tubulin alpha chain 0.073 0.9104 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0374 0.0374
Brugia malayi phosphofructokinase 0.0107 0.1254 0.1372
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trichomonas vaginalis adenylate cyclase, putative 0.0012 0.0058 0.0057
Schistosoma mansoni lamin 0.0027 0.0236 0.0259
Entamoeba histolytica tubulin alpha chain, putative 0.073 0.9104 1
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0374 0.0411
Mycobacterium tuberculosis Probable reductase 0.0107 0.1244 0.5386
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0374 0.0411
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0191 0.2304 0.2526
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.001 0.0004
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.046 0.0499
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0104 0.0114
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.0023 0.019 0.0202
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0009
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0374 0.0405
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0266 0.0286
Echinococcus multilocularis pyruvate kinase 0.0033 0.0316 0.0316
Toxoplasma gondii beta-1 tubulin, putative 0.0597 0.742 0.8148
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.1254 0.5431
Schistosoma mansoni hypothetical protein 0.0167 0.2011 0.2208
Echinococcus multilocularis Tubulin beta 2C chain 0.0597 0.742 0.742
Echinococcus granulosus neuropeptide s receptor 0.0038 0.0374 0.0411
Echinococcus multilocularis neuropeptide receptor A26 0.0038 0.0374 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Leishmania major beta tubulin 0.0597 0.742 0.8141
Loa Loa (eye worm) hypothetical protein 0.0161 0.1933 0.2118
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0374 0.0374
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0104 0.0069
Schistosoma mansoni cpg binding protein 0.0029 0.0267 0.0293
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0615 0.0675
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0279 0.0301
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0104 0.0108
Echinococcus granulosus g protein coupled receptor 0.0038 0.0374 0.0411
Echinococcus multilocularis tubulin alpha 3 chain 0.073 0.9104 0.9104
Schistosoma mansoni biogenic amine receptor 0.0038 0.0374 0.0411
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1254 0.1372
Plasmodium vivax tubulin alpha chain, putative 0.073 0.9104 1
Leishmania major pyruvate kinase 0.0033 0.0316 0.0302
Echinococcus granulosus beta tubulin 0.0597 0.742 0.815
Leishmania major gamma-tubulin 0.0439 0.5437 0.5953
Leishmania major alpha tubulin 0.073 0.9104 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0615 0.2649
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0088 0.009
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0127 0.0134
Echinococcus multilocularis peroxisome assembly protein 26 0.073 0.9104 0.9104
Trichomonas vaginalis tubulin gamma chain, putative 0.0597 0.742 0.8148
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.25 0.2741
Mycobacterium ulcerans sulfatase 0.0008 0.0007 0.0006
Leishmania major alpha tubulin 0.073 0.9104 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0316 0.0341
Trichomonas vaginalis tubulin alpha chain, putative 0.0249 0.3033 0.3327
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0374 0.0411
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0012 0.0058 0.0058
Toxoplasma gondii exonuclease III APE 0.0018 0.0127 0.0134
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Schistosoma mansoni hypothetical protein 0.0167 0.2011 0.2208
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0133 0.0139
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0012 0.0058 0.0063
Trichomonas vaginalis tubulin, putative 0.0597 0.742 0.8148
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0127 0.014
Leishmania major beta tubulin 0.0597 0.742 0.8141
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Echinococcus granulosus tubulin epsilon chain 0.0439 0.5437 0.5972
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0374 0.0374
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0374 0.0411
Echinococcus granulosus tubulin alpha 3 chain 0.073 0.9104 1
Loa Loa (eye worm) phosphofructokinase 0.0107 0.1254 0.1372
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0202 0.0216
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0615 0.2649
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Echinococcus granulosus tubulin alpha chain 0.073 0.9104 1
Plasmodium falciparum tubulin epsilon chain, putative 0.0439 0.5437 0.5967
Echinococcus multilocularis tubulin beta 1 chain 0.0597 0.742 0.742
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0316 0.034
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0104 0.1807
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0571 0.0622
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Schistosoma mansoni pyruvate kinase 0.0033 0.0316 0.0347
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0615 0.0632
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0088 0.009
Trichomonas vaginalis tubulin beta chain, putative 0.0249 0.3033 0.3327
Schistosoma mansoni tubulin subunit beta 0.0597 0.742 0.815
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0127 0.0094
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0104 0.0104
Loa Loa (eye worm) histone methyltransferase 0.001 0.0021 0.0017
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0104 0.0429
Echinococcus granulosus serine protein kinase ATM 0.0008 0.0006 0.0007
Schistosoma mansoni tubulin subunit beta 0.0597 0.742 0.815
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0104 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0266 0.0282
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0062
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0249 0.3033 0.3327
Onchocerca volvulus 0.0038 0.0374 0.1214
Loa Loa (eye worm) hypothetical protein 0.0012 0.0058 0.0057
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0266 0.0286
Echinococcus multilocularis Tubulin beta 2C chain 0.0597 0.742 0.742
Leishmania major alpha tubulin 0.073 0.9104 1
Trichomonas vaginalis tubulin beta chain, putative 0.073 0.9104 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0012 0.0058 0.0063
Brugia malayi ORL1-like opioid receptor 0.0038 0.0374 0.0405
Schistosoma mansoni ferritin 0.0008 0.0006 0.0006
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0316 0.034
Trypanosoma cruzi tubulin delta chain 0.0191 0.2304 0.2526
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0058 0.0057
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0091 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Brugia malayi neuropeptide F receptor 0.0038 0.0374 0.0405
Loa Loa (eye worm) tubulin beta-4 chain 0.0597 0.742 0.8148
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0127 0.0134
Trichomonas vaginalis tubulin epsilon chain, putative 0.073 0.9104 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0279 0.0279
Schistosoma mansoni alpha tubulin 0.073 0.9104 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0258 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0088 0.009
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0058 0.0057
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0666 0.0666
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0127 0.0134
Entamoeba histolytica tubulin alpha-1 chain 0.073 0.9104 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0088 0.009
Onchocerca volvulus 0.0036 0.0349 0.1129
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0374 0.0374
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0104 0.0108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Echinococcus multilocularis lamin dm0 0.0027 0.0236 0.0236
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0374 0.0411
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0279 0.0307
Schistosoma mansoni apoferritin-2 0.0008 0.0006 0.0006
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0191 0.2304 0.2526
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0349 0.1492
Echinococcus granulosus Tubulin beta 2C chain 0.0597 0.742 0.815
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0104 0.0027
Echinococcus granulosus tubulin alpha 1C chain 0.073 0.9104 1
Trypanosoma cruzi tubulin gamma chain 0.0439 0.5437 0.5969
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0453 0.0498
Brugia malayi putative neuropeptide receptor 0.0038 0.0374 0.0405
Trichomonas vaginalis tubulin, putative 0.0191 0.2304 0.2526
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0453 0.0491
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0374 0.1214
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.001 0.0003
Onchocerca volvulus 0.0038 0.0374 0.1214
Echinococcus granulosus hypothetical protein 0.0038 0.0374 0.0411
Schistosoma mansoni tubulin subunit alpha 0.073 0.9104 1
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0316 0.034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.046 0.0499
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0226 0.0242
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0374 0.0411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0202 0.0216
Echinococcus granulosus single minded 2 0.0036 0.0349 0.0383
Trypanosoma brucei trypanothione reductase 0.0047 0.0489 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Echinococcus multilocularis sex peptide receptor 0.0038 0.0374 0.0374
Trichomonas vaginalis tubulin epsilon chain, putative 0.0597 0.742 0.8148
Schistosoma mansoni hypothetical protein 0.0038 0.0374 0.0411
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0566 0.0616
Echinococcus granulosus geminin 0.0167 0.2011 0.2208
Echinococcus granulosus lamin 0.0027 0.0236 0.0259
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0374 0.0411
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0374 0.0374
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0088 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Echinococcus multilocularis aryl hydrocarbon receptor 0.0012 0.0058 0.0058
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0374 0.0374
Schistosoma mansoni tubulin subunit epsilon 0.0439 0.5437 0.5972
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.001 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0374 0.0411
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0012 0.0058 0.0057
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0104 0.0027
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Loa Loa (eye worm) tubulin alpha 2 0.0291 0.3568 0.3915
Brugia malayi sulfakinin receptor protein 0.0038 0.0374 0.0405
Trypanosoma brucei alpha tubulin 0.073 0.9104 1
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Schistosoma mansoni pyruvate kinase 0.0033 0.0316 0.0347
Giardia lamblia Beta tubulin 0.0597 0.742 0.8148
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0127 0.0134
Loa Loa (eye worm) RNA binding protein 0.0061 0.0666 0.0725
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0374 0.0374
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0503 0.0546
Leishmania major beta tubulin 0.0597 0.742 0.8141
Plasmodium vivax tubulin alpha chain, putative 0.073 0.9104 1
Chlamydia trachomatis pyruvate kinase 0.0033 0.0316 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0374 0.0411
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0104 0.0107
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0666 0.0725
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0374 0.0405
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.1244 0.5386
Loa Loa (eye worm) hypothetical protein 0.0313 0.3851 0.4227
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0374 0.0374
Brugia malayi Dopamine receptor protein 2 0.0038 0.0374 0.0405
Brugia malayi larval opioid receptor 0.0038 0.0374 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0374 0.0374
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0374 0.0411
Entamoeba histolytica tubulin gamma chain 0.0439 0.5437 0.5969
Echinococcus granulosus lamin dm0 0.0027 0.0236 0.0259
Echinococcus multilocularis tubulin alpha chain 0.073 0.9104 0.9104
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.046 0.0499
Leishmania major alpha tubulin 0.073 0.9104 1
Brugia malayi Cytochrome P450 family protein 0.0026 0.0226 0.0242
Toxoplasma gondii beta tubulin 0.0597 0.742 0.8148
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0104 0.0108
Loa Loa (eye worm) hypothetical protein 0.0026 0.023 0.0246
Schistosoma mansoni DNA helicase recq1 0.0009 0.001 0.0011
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0008 0.0006 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.1244 0.5386
Schistosoma mansoni lamin 0.0027 0.0236 0.0259
Schistosoma mansoni ap endonuclease 0.0018 0.0127 0.014
Toxoplasma gondii beta-tubulin, putative 0.0597 0.742 0.8148
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0231 0.0248
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0316 0.102
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0008 0.0007 0.0006
Plasmodium falciparum tubulin gamma chain 0.0439 0.5437 0.5967
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0127 0.053
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0042 0.004
Plasmodium falciparum pyruvate kinase 0.0033 0.0316 0.0336
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.001 0.0011
Echinococcus multilocularis cpg binding protein 0.0029 0.0267 0.0267
Schistosoma mansoni amine GPCR 0.0038 0.0374 0.0411
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Leishmania major beta tubulin 0.0597 0.742 0.8141
Schistosoma mansoni hypothetical protein 0.0015 0.0091 0.01
Echinococcus multilocularis Tubulin beta 2C chain 0.0597 0.742 0.742
Schistosoma mansoni amine GPCR 0.0038 0.0374 0.0411
Onchocerca volvulus 0.0027 0.0236 0.0757
Trichomonas vaginalis tubulin, putative 0.0249 0.3033 0.3327
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.005 0.0049
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0374 0.0411
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Echinococcus granulosus ferritin 0.0008 0.0006 0.0006
Brugia malayi G protein-coupled receptor 0.0038 0.0374 0.0405
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0266 0.1132
Leishmania major alpha tubulin 0.073 0.9104 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.0374 0.0411
Schistosoma mansoni tubulin subunit alpha 0.073 0.9104 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.046 0.0499
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0374 0.0405
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0666 0.0731
Brugia malayi GnHR receptor homolog 0.0038 0.0374 0.0405
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0453 0.0498
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.1393 0.6038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0316 0.0341
Schistosoma mansoni tubulin subunit beta 0.0597 0.742 0.815
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Treponema pallidum NADH oxidase 0.0016 0.0104 0.0429
Echinococcus granulosus pyruvate kinase 0.0017 0.0113 0.0124
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0104 0.0108
Loa Loa (eye worm) hypothetical protein 0.0012 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trypanosoma cruzi beta tubulin, putative 0.0597 0.742 0.8148
Schistosoma mansoni tubulin subunit beta 0.0597 0.742 0.815
Onchocerca volvulus 0.0027 0.0236 0.0757
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0374 0.0374
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0374 0.0374
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1254 0.1372
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1254 0.1372
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0482 0.5972 0.6557
Brugia malayi G-protein coupled receptor 0.0038 0.0374 0.0405
Onchocerca volvulus 0.0038 0.0374 0.1214
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0127 0.0132
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0104 0.0069
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0088 0.005
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0113 0.0037
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0104 0.0429
Onchocerca volvulus 0.0038 0.0374 0.1214
Trypanosoma brucei epsilon tubulin 0.0439 0.5437 0.5969
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0316 0.0341
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0088 0.009
Echinococcus multilocularis pyruvate kinase 0.0017 0.0113 0.0113
Loa Loa (eye worm) tubulin alpha-2 chain 0.073 0.9104 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0374 0.0374
Loa Loa (eye worm) alpha-tubulin 0.073 0.9104 1
Schistosoma mansoni hypothetical protein 0.0038 0.0374 0.0411
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0091 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0374 0.0411
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0374 0.0374
Brugia malayi G-protein coupled receptor 0.0038 0.0374 0.0405
Loa Loa (eye worm) hypothetical protein 0.073 0.9104 1
Echinococcus granulosus fmrfamide receptor 0.0038 0.0374 0.0411
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0374 0.0411
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Brugia malayi Tubulin alpha-2 chain 0.073 0.9104 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0374 0.0405
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0058 0.0057
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0058 0.0057
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0615 0.2649
Trichomonas vaginalis tubulin alpha chain, putative 0.0249 0.3033 0.3327
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0058 0.0057
Echinococcus multilocularis somatostatin receptor 0.0038 0.0374 0.0374
Leishmania major beta tubulin 0.0597 0.742 0.8141
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0042 0.004
Trypanosoma cruzi epsilon tubulin, putative 0.0439 0.5437 0.5969
Brugia malayi Serotonin receptor 0.0038 0.0374 0.0405
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.1254 0.5431
Trypanosoma brucei alpha tubulin, putative 0.0249 0.3033 0.3327
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0316 0.0341
Schistosoma mansoni DNA helicase recq5 0.0009 0.001 0.0011
Leishmania major alpha tubulin 0.073 0.9104 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0279 0.0307
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0008 0.0007 0.0001
Mycobacterium ulcerans arylsulfatase AtsD 0.0008 0.0007 0.0006
Schistosoma mansoni cpg binding protein 0.0029 0.0267 0.0293
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0374 0.0411
Echinococcus granulosus Tubulin alpha 1 chain 0.073 0.9104 1
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Toxoplasma gondii alpha tubulin TUBA1 0.073 0.9104 1
Brugia malayi Serotonin receptor 0.0038 0.0374 0.0405
Brugia malayi intermediate filament protein 0.0027 0.0236 0.0253
Echinococcus granulosus Tubulin beta 2C chain 0.0597 0.742 0.815
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0265 0.3239 0.3554
Schistosoma mansoni ferritin light chain 0.0008 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Brugia malayi TAR-binding protein 0.0061 0.0666 0.0725
Echinococcus multilocularis GPCR, family 2 0.0015 0.0091 0.0091
Trichomonas vaginalis tubulin beta chain, putative 0.073 0.9104 1
Trypanosoma brucei tubulin gamma chain 0.0439 0.5437 0.5969
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Leishmania major pyruvate kinase 0.0033 0.0316 0.0302
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0004
Schistosoma mansoni amine GPCR 0.0038 0.0374 0.0411
Echinococcus multilocularis ferritin 0.0008 0.0006 0.0006
Brugia malayi Tubulin beta chain 0.0191 0.2304 0.2526
Trichomonas vaginalis conserved hypothetical protein 0.0191 0.2304 0.2526
Trypanosoma brucei beta tubulin 0.0597 0.742 0.8148
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0453 0.0491
Trypanosoma brucei alpha tubulin 0.073 0.9104 1
Brugia malayi Tubulin alpha chain 0.0191 0.2304 0.2526
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0104 0.0108
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0597 0.742 0.742
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1254 0.1372
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0374 0.0411
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0374 0.0374
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0453 0.0498
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.019 0.0202
Plasmodium vivax delta tubulin, putative 0.0191 0.2304 0.2465
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Onchocerca volvulus 0.003 0.0279 0.0901
Echinococcus multilocularis Tubulin alpha 1 chain 0.073 0.9104 0.9104
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0374 0.0411
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.011 0.0121
Brugia malayi hypothetical protein 0.0008 0.0007 0.0001
Leishmania major protein kinase, putative 0.0012 0.0058 0.0017
Onchocerca volvulus 0.0038 0.0374 0.1214
Echinococcus granulosus tubulin alpha 1C chain 0.073 0.9104 1
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0012 0.0058 0.0057
Brugia malayi hypothetical protein 0.0038 0.0374 0.0405
Brugia malayi follicle stimulating hormone receptor 0.0265 0.3239 0.3554
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0266 0.8073
Entamoeba histolytica tubulin family protein 0.0597 0.742 0.8148
Echinococcus multilocularis tubulin alpha chain 0.073 0.9104 0.9104
Echinococcus multilocularis tubulin epsilon chain 0.0439 0.5437 0.5437
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0062 0.0062
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1254 0.1377
Schistosoma mansoni histamine h1 receptor 0.0038 0.0374 0.0411
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0374 0.0411
Echinococcus granulosus pyruvate kinase 0.0017 0.0113 0.0124
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0453 0.0453
Onchocerca volvulus 0.0038 0.0374 0.1214
Toxoplasma gondii thioredoxin reductase 0.0047 0.0489 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0266 0.0286
Giardia lamblia Gamma tubulin 0.0439 0.5437 0.5969
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0008 0.0007 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0666 0.0731
Trichomonas vaginalis tubulin beta chain, putative 0.0597 0.742 0.8148
Leishmania major beta tubulin 0.0597 0.742 0.8141
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.1254 0.1337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0088 0.009
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0374 0.0411
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0088 0.0096
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0091 0.0093
Brugia malayi Tubulin alpha chain 0.073 0.9104 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0374 0.0411
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.073 0.9104 1
Trypanosoma brucei tubulin delta chain 0.0191 0.2304 0.2526
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0374 0.0411
Brugia malayi RE15519p 0.0038 0.0374 0.0405
Mycobacterium ulcerans cell division protein FtsZ 0.0191 0.2304 1
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0236 0.0253
Leishmania major delta tubulin, putative 0.0191 0.2304 0.2496
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0374 0.0374
Leishmania major alpha tubulin 0.073 0.9104 1
Schistosoma mansoni opsin-like receptor 0.0038 0.0374 0.0411
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0166 0.0176
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0013
Echinococcus granulosus tubulin alpha chain 0.073 0.9104 1
Leishmania major beta tubulin 0.0597 0.742 0.8141
Loa Loa (eye worm) tubulin gamma chain 0.0439 0.5437 0.5969
Echinococcus granulosus neuropeptide receptor A26 0.0038 0.0374 0.0411
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0374 0.0411
Echinococcus multilocularis neuropeptide s receptor 0.0038 0.0374 0.0374
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0236 0.0253
Schistosoma mansoni ferritin 0.0008 0.0006 0.0006
Echinococcus granulosus neuropeptide receptor 0.0038 0.0374 0.0411
Schistosoma mansoni hypothetical protein 0.0033 0.0312 0.0343
Brugia malayi Pre-SET motif family protein 0.0206 0.25 0.2741
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0374 0.0411
Schistosoma mansoni neuropeptide receptor 0.0038 0.0374 0.0411
Plasmodium falciparum thioredoxin reductase 0.0047 0.0489 0.0527
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Echinococcus granulosus tubulin subunit beta 0.0597 0.742 0.815
Brugia malayi Tubulin alpha-2 chain 0.073 0.9104 1
Schistosoma mansoni amine GPCR 0.0038 0.0374 0.0411
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0506 0.0556
Schistosoma mansoni ferritin 0.0008 0.0006 0.0006
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.0026 0.0022
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0374 0.0405
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0058 0.0057
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0001
Giardia lamblia Beta tubulin 0.0597 0.742 0.8148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0236 0.0253
Leishmania major beta tubulin 0.0597 0.742 0.8141
Echinococcus multilocularis pyruvate kinase 0.0033 0.0316 0.0316
Echinococcus granulosus tar DNA binding protein 0.0061 0.0666 0.0731
Brugia malayi Tubulin beta chain 0.0249 0.3033 0.3327
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.001 0.0011
Trichomonas vaginalis tubulin beta chain, putative 0.073 0.9104 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.001 0.0004
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0374 0.0411
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0166 0.0176
Trichomonas vaginalis tubulin gamma chain, putative 0.0439 0.5437 0.5969
Giardia lamblia Delta tubulin 0.0191 0.2304 0.2525
Plasmodium falciparum alpha tubulin 1 0.073 0.9104 1
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0127 0.0134
Trypanosoma brucei alpha tubulin 0.073 0.9104 1
Onchocerca volvulus 0.0028 0.0247 0.0794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0345 0.0373
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0374 0.0411
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0374 0.0374
Brugia malayi Sulfatase family protein 0.0008 0.0007 0.0001
Loa Loa (eye worm) tubulin alpha-3 chain 0.0482 0.5972 0.6557
Brugia malayi Cell division protein ftsZ 0.0191 0.2304 0.2526
Echinococcus granulosus Tubulin alpha 1 chain 0.073 0.9104 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0346 0.0373
Loa Loa (eye worm) hypothetical protein 0.0048 0.0503 0.0546
Echinococcus granulosus bloom syndrome protein 0.0021 0.0166 0.0182
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0666 0.0731
Leishmania major zeta tubulin, putative 0.0191 0.2304 0.2496
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0312 0.0336
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0374 0.0374
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0316 0.1348
Onchocerca volvulus 0.0038 0.0374 0.1214
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0266 0.0286
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0266 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0088 0.009
Schistosoma mansoni tubulin subunit beta 0.0597 0.742 0.815
Echinococcus multilocularis pyruvate kinase 0.0026 0.0228 0.0228
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0374 0.0374
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0104 0.0114
Trypanosoma brucei alpha tubulin 0.073 0.9104 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0374 0.0411
Schistosoma mansoni alpha tubulin 0.073 0.9104 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0231 0.0248
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0113 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0316 0.0341
Echinococcus multilocularis tubulin alpha 3 chain 0.073 0.9104 0.9104
Echinococcus granulosus Tubulin beta 2C chain 0.0597 0.742 0.815
Loa Loa (eye worm) tubulin alpha chain 0.073 0.9104 1
Onchocerca volvulus 0.0235 0.2858 0.9422
Brugia malayi alpha-tubulin 0.073 0.9104 1
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0008 0.0006 0.0006
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.1244 0.5386
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0374 0.0411
Echinococcus multilocularis hypothetical protein 0.073 0.9104 0.9104
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Brugia malayi AKH receptor 0.0038 0.0374 0.0405
Leishmania major alpha tubulin 0.073 0.9104 1
Schistosoma mansoni alpha tubulin 0.073 0.9104 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0374 0.0405
Echinococcus granulosus tubulin beta 4A class IVa 0.0597 0.742 0.815
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.1393 0.6038
Echinococcus granulosus peroxisome assembly protein 26 0.073 0.9104 1
Echinococcus multilocularis tubulin alpha 0.0439 0.5437 0.5437
Onchocerca volvulus 0.0249 0.3033 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0374 0.1214
Trypanosoma brucei beta tubulin 0.0597 0.742 0.8148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0088 0.009
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0058 0.0057
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0127 0.053
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0374 0.0411
Leishmania major beta tubulin 0.0597 0.742 0.8141
Plasmodium falciparum thioredoxin reductase 0.0016 0.0104 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0202 0.0216
Onchocerca volvulus 0.0038 0.0374 0.1214
Giardia lamblia Alpha-tubulin 0.073 0.9104 1
Echinococcus granulosus Tubulin alpha 1 chain 0.073 0.9104 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0597 0.742 0.742
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0374 0.0405
Trichomonas vaginalis tubulin, putative 0.0249 0.3033 0.3327
Leishmania major protein kinase, putative 0.0012 0.0058 0.0017

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) 0 nM Displacement of [3H]-PDBU from protein kinase C-alpha (Inactive) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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