Detailed information for compound 335774

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 332.268 | Formula: C16H15NO5P---
  • H donors: 0 H acceptors: 5 LogP: 0.81 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]N(C(=O)c1ccc(cc1)c1ccccc1)CCCP(=O)([O-])[O-]
  • InChi: 1S/C16H17NO5P/c18-16(17(19)11-4-12-23(20,21)22)15-9-7-14(8-10-15)13-5-2-1-3-6-13/h1-3,5-10H,4,11-12H2,(H2,20,21,22)/q-1/p-2
  • InChiKey: OYNOVJNAUQYJES-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.0094 0.009
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.033 0.3175 0.3172
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.009 0.018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0059 0.0059
Brugia malayi CXXC zinc finger family protein 0.0017 0.0111 0.0107
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.015 0.0146
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0011 0.0054 0.005
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0011 0.0054 0.0407
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Plasmodium vivax SET domain protein, putative 0.0038 0.0318 0.063
Schistosoma mansoni hypothetical protein 0.0015 0.0094 0.0189
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0059 0.012
Brugia malayi RNA recognition motif domain containing protein 0.0129 0.1204 0.1201
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0512 0.4958 0.4956
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0015 0.0094 0.0068
Echinococcus granulosus glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Echinococcus granulosus lamin dm0 0.0039 0.0324 0.0324
Toxoplasma gondii exonuclease III APE 0.0014 0.008 0.0159
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.008 0.0276
Echinococcus multilocularis glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Brugia malayi ORL1-like opioid receptor 0.0015 0.0094 0.009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0094 0.0094
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0059 0.0033
Schistosoma mansoni heat shock protein 0.0072 0.0645 0.1302
Echinococcus granulosus glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Brugia malayi latrophilin 2 splice variant baaae 0.006 0.053 0.0526
Schistosoma mansoni hypothetical protein 0.0051 0.0438 0.0884
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Schistosoma mansoni hypothetical protein 0.0028 0.0214 0.0432
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0018 0.0116 0.0937
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0094 0.0094
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0162 0.1329
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.1026 1 1
Onchocerca volvulus 0.0015 0.0094 0.0068
Loa Loa (eye worm) CXXC zinc finger family protein 0.0017 0.0111 0.0107
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.1026 1 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.0036 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0038 0.0318 0.0641
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Schistosoma mansoni ap endonuclease 0.0014 0.008 0.0161
Loa Loa (eye worm) ICD-1 protein 0.0021 0.0148 0.0144
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis geminin 0.0444 0.4294 0.4294
Schistosoma mansoni neuropeptide receptor 0.0015 0.0094 0.0189
Plasmodium falciparum endoplasmin, putative 0.005 0.0432 0.0857
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0265 0.2538 0.2535
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Schistosoma mansoni smad1 5 8 and 0.001 0.0036 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0059 0.0055
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Brugia malayi hypothetical protein 0.0018 0.0119 0.0115
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Onchocerca volvulus 0.0009 0.0033 0.0006
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0014 0.008 0.0145
Onchocerca volvulus 0.0015 0.0094 0.0068
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0065 0.0576 0.1131
Echinococcus multilocularis musashi 0.0039 0.0324 0.0324
Onchocerca volvulus 0.0015 0.0094 0.0068
Trypanosoma brucei metallo- peptidase, Clan M- Family M48 0.004 0.033 0.2897
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0014 0.008 0.0269
Schistosoma mansoni lamin 0.0039 0.0324 0.0653
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Giardia lamblia Hypothetical protein 0.0109 0.1006 0.5054
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.033 0.3175 0.3172
Schistosoma mansoni hypothetical protein 0.0028 0.0214 0.0432
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0094 0.0094
Toxoplasma gondii DNA topoisomerase 2, putative 0.0011 0.0054 0.0108
Loa Loa (eye worm) hypothetical protein 0.0011 0.0054 0.005
Entamoeba histolytica acyl-coA synthetase, putative 0.0018 0.0116 0.0583
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0094 0.0094
Mycobacterium ulcerans DNA gyrase subunit B 0.0011 0.0054 0.0094
Echinococcus multilocularis neuropeptide s receptor 0.0825 0.8027 0.8027
Schistosoma mansoni biogenic amine receptor 0.0015 0.0094 0.0189
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0059 0.0055
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.0007 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.001 0.004 0.0065
Entamoeba histolytica heat shock protein 90, putative 0.0072 0.0645 0.3243
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0018 0.0116 0.0216
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0059 0.0055
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0011 0.0054 0.0188
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0059 0.0055
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0109 0.1006 0.1002
Mycobacterium ulcerans bacterioferritin BfrB 0.001 0.004 0.0065
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0301 0.2896 0.2878
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0578 0.1166
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus neuropeptide receptor A26 0.0825 0.8027 0.8027
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.008 0.0269
Loa Loa (eye worm) endoplasmin 0.0072 0.0645 0.0642
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.033 0.3175 0.3172
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0006 0.0004 0.0008
Echinococcus granulosus endoplasmin 0.0065 0.0576 0.0576
Echinococcus multilocularis survival motor neuron protein 1 0.0248 0.2375 0.2375
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Schistosoma mansoni nAChR subunit 0.0145 0.1367 0.2758
Onchocerca volvulus 0.0184 0.175 0.1728
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.033 0.3175 0.3172
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.052 0.5037 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0094 0.0189
Mycobacterium leprae Probable two component sensor kinase MprB 0.0011 0.0054 0.0094
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0013 0.0072 0.0129
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0021 0.0147 0.0143
Loa Loa (eye worm) acetylcholine receptor protein 0.0145 0.1367 0.1364
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0011 0.0054 0.0094
Brugia malayi hypothetical protein 0.0063 0.0562 0.0559
Mycobacterium ulcerans putative regultory protein 0.0011 0.0054 0.0094
Schistosoma mansoni neurotransmitter gated ion channel 0.0184 0.175 0.3529
Trichomonas vaginalis heat shock protein, putative 0.005 0.0432 0.1491
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0059 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0013 0.0072 0.0035
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0059 0.0059
Trichomonas vaginalis set domain proteins, putative 0.0301 0.2896 1
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.033 0.3175 0.3175
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.033 0.3175 0.3172
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Echinococcus multilocularis serotonin receptor 0.0015 0.0094 0.0094
Brugia malayi Calcitonin receptor-like protein seb-1 0.0088 0.0802 0.0798
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Onchocerca volvulus Cell death protein 3 homolog 0.0018 0.0119 0.0093
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0184 0.175 0.1746
Echinococcus granulosus neuropeptide receptor 0.0015 0.0094 0.0094
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0011 0.0054 0.0094
Entamoeba histolytica CAAX amino terminal protease family 0.0022 0.0162 0.0812
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0145 0.1367 0.1364
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.015 0.0519
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Trypanosoma cruzi heat shock protein 85, putative 0.0072 0.0645 0.6211
Entamoeba histolytica acyl-CoA synthetase, putative 0.0018 0.0116 0.0583
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0094 0.009
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0011 0.0054 0.0054
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0125 0.0121
Echinococcus multilocularis Smad4 0.001 0.0036 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0512 0.4958 0.4944
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0094 0.0189
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0094 0.0189
Onchocerca volvulus 0.0039 0.0324 0.0298
Echinococcus granulosus transcription factor btf3 0.0021 0.0148 0.0148
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0094 0.0094
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.1026 1 1
Brugia malayi hypothetical protein 0.001 0.0038 0.0034
Echinococcus multilocularis caax prenyl protease 1 0.004 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Trypanosoma brucei heat shock protein 84, putative 0.0043 0.0363 0.3239
Brugia malayi MH1 domain containing protein 0.001 0.0036 0.0032
Entamoeba histolytica hypothetical protein 0.0021 0.0148 0.0744
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0094 0.009
Onchocerca volvulus 0.033 0.3175 0.3157
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0578 0.4919
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0059 0.0055
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0109 0.1006 0.2029
Trichomonas vaginalis sensor histidine kinase, putative 0.0011 0.0054 0.0188
Schistosoma mansoni apoferritin-2 0.001 0.004 0.008
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0059 0.0055
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0094 0.0189
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0059 0.012
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0116 0.0216
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0318 0.0641
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0059 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0059 0.0059
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0094 0.009
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.004 0.033 0.114
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.033 0.3175 0.6404
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0011 0.0054 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0116 0.0216
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0119 0.0115
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0059 0.0059
Brugia malayi Cell death protein 3 precursor 0.0018 0.0119 0.0115
Plasmodium falciparum acyl-CoA synthetase 0.0013 0.0072 0.0143
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0014 0.008 0.0402
Trichomonas vaginalis receptor histidine kinase, putative 0.0011 0.0054 0.0188
Schistosoma mansoni endoplasmin 0.0072 0.0645 0.1302
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0116 0.0112
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0125 0.0125
Brugia malayi Peptidase family M48 containing protein 0.004 0.033 0.0326
Schistosoma mansoni adenoreceptor 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0042 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0009 0.0033 0.0029
Trypanosoma cruzi heat shock protein 85, putative 0.0072 0.0645 0.6211
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0059 0.0055
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0094 0.0094
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0021 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Toxoplasma gondii hypothetical protein 0.0022 0.0162 0.0321
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0122
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0059 0.0055
Schistosoma mansoni hypothetical protein 0.0246 0.2352 0.4744
Mycobacterium tuberculosis Probable two component sensor kinase 0.0011 0.0054 0.0407
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0011 0.0054 0.0108
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0011 0.0054 0.0407
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0094 0.0068
Schistosoma mansoni hypothetical protein 0.0007 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi AKH receptor 0.0015 0.0094 0.009
Treponema pallidum heat shock protein 90 0.0065 0.0576 0.1073
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0059 0.0059
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0021 0.015 0.015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.1026 1 1
Schistosoma mansoni neuropeptide receptor 0.0015 0.0094 0.0189
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0094 0.0094
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0011 0.0054 0.0094
Echinococcus granulosus expressed protein 0.001 0.004 0.004
Plasmodium vivax DNA gyrase subunit B, putative 0.0011 0.0054 0.0108
Plasmodium vivax DNA topoisomerase II, putative 0.0011 0.0054 0.0108
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0038 0.0318 0.063
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0116 0.0647
Entamoeba histolytica CAAX prenyl protease family 0.0109 0.1006 0.5054
Echinococcus multilocularis neuropeptide receptor A26 0.0825 0.8027 0.8027
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0094 0.0094
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0116 0.0112
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0059 0.0055
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0578 0.5503
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0011 0.0054 0.0407
Schistosoma mansoni intermediate filament proteins 0.0039 0.0324 0.0653
Entamoeba histolytica CAAX amino terminal protease family 0.0022 0.0162 0.0812
Schistosoma mansoni neuropeptide receptor 0.0015 0.0094 0.0189
Brugia malayi kinase, mitochondrial precursor 0.0011 0.0054 0.005
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0059 0.012
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0094 0.0189
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0059 0.0059
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.033 0.3175 0.3175
Trichomonas vaginalis endoplasmin, putative 0.005 0.0432 0.1491
Loa Loa (eye worm) hypothetical protein 0.0028 0.0214 0.021
Onchocerca volvulus 0.0015 0.0094 0.0068
Echinococcus multilocularis nAChR subunit 0.0184 0.175 0.175
Brugia malayi MH1 domain containing protein 0.001 0.0036 0.0032
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0059 0.0059
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0094 0.0094
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0021 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Loa Loa (eye worm) hypothetical protein 0.0088 0.0802 0.0798
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0512 0.4958 0.4956
Onchocerca volvulus 0.0015 0.0094 0.0068
Onchocerca volvulus Glucosylceramidase homolog 0.0102 0.094 0.0916
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0006 0.0004 0.0004
Echinococcus granulosus hypothetical protein 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0018 0.0116 0.009
Echinococcus multilocularis GPCR, family 2 0.0028 0.0214 0.0214
Trichomonas vaginalis ferritin, putative 0.001 0.004 0.0137
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0059 0.0055
Echinococcus granulosus glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Toxoplasma gondii hypothetical protein 0.0022 0.0162 0.0321
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0011 0.0054 0.0108
Schistosoma mansoni histamine h1 receptor 0.0015 0.0094 0.0189
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.008 0.0159
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Mycobacterium ulcerans hypothetical protein 0.0022 0.0162 0.0307
Onchocerca volvulus 0.0017 0.0111 0.0085
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0125 0.0125
Trypanosoma cruzi metallo- peptidase, Clan M- Family M48 0.004 0.033 0.2897
Schistosoma mansoni hypothetical protein 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0094 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Echinococcus granulosus heat shock protein 90 0.006 0.0533 0.0533
Trichomonas vaginalis heat shock protein, putative 0.006 0.0533 0.184
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.096 0.9356 0.9356
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Onchocerca volvulus 0.0015 0.0094 0.0068
Schistosoma mansoni cpg binding protein 0.0018 0.0121 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.0242
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0059 0.0059
Echinococcus multilocularis heat shock protein 90 0.006 0.0533 0.0533
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.0356 0.0718
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0109 0.1006 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0015 0.009 0.0379
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0059 0.0059
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0011 0.0054 0.0407
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0018 0.0116 0.0216
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0155 0.1463 0.146
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0094 0.0189
Loa Loa (eye worm) DOMON domain-containing protein 0.0009 0.0026 0.0022
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0094 0.0094
Schistosoma mansoni biogenic amine receptor 0.0015 0.0094 0.0189
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0065 0.0576 0.1131
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0094 0.0094
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0009 0.0033 0.0006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0038 0.0317 0.0313
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0065 0.0497
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0038 0.0318 0.0318
Trichomonas vaginalis receptor histidine kinase, putative 0.0011 0.0054 0.0188
Onchocerca volvulus 0.0039 0.0324 0.0298
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0094 0.0094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Onchocerca volvulus 0.0512 0.4958 0.4944
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0094 0.0094
Brugia malayi follicle stimulating hormone receptor 0.0015 0.0094 0.009
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0018 0.0119 0.0115
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Mycobacterium ulcerans two component regulator - sensor kinase 0.0011 0.0054 0.0094
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0094 0.0094
Trichomonas vaginalis heat shock protein, putative 0.0038 0.0319 0.1103
Echinococcus multilocularis apoptotic protease activating factor 1 0.0018 0.0119 0.0119
Schistosoma mansoni acetylcholine receptor-related 0.0145 0.1367 0.2758
Entamoeba histolytica hypothetical protein 0.0063 0.0562 0.2826
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0011 0.0054 0.0054
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0315 0.0634
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0578 0.1134
Loa Loa (eye worm) histone methyltransferase 0.0007 0.0008 0.0004
Schistosoma mansoni neuropeptide receptor 0.0015 0.0094 0.0189
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis heat shock protein 0.0072 0.0645 0.0645
Onchocerca volvulus 0.0015 0.0094 0.0068
Schistosoma mansoni hypothetical protein 0.0014 0.0082 0.0165
Echinococcus granulosus g protein coupled receptor 0.0015 0.0094 0.0094
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0011 0.0054 0.0108
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0014 0.008 0.0269
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0059 0.0055
Schistosoma mansoni heat shock protein 0.0043 0.0363 0.0731
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Toxoplasma gondii NAC domain-containing protein 0.0021 0.0148 0.0294
Brugia malayi putative neuropeptide receptor 0.0015 0.0094 0.009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0037 0.03 0.03
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0145 0.1367 0.1367
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Toxoplasma gondii histone lysine methyltransferase SET1 0.0034 0.0276 0.0548
Trichomonas vaginalis heat shock protein, putative 0.0065 0.0576 0.1989
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Plasmodium falciparum heat shock protein 90, putative 0.0209 0.1989 0.3947
Loa Loa (eye worm) hypothetical protein 0.0366 0.3533 0.353
Plasmodium vivax basic transcription factor 3b, putative 0.0021 0.0148 0.0294
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0011 0.0054 0.0029
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) LGC-31 protein 0.033 0.3175 0.3172
Brugia malayi hypothetical protein 0.0248 0.2375 0.2372
Giardia lamblia Pms1-like protein 0.0011 0.0054 0.0274
Brugia malayi CAAX amino terminal protease family protein 0.0109 0.1006 0.1002
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.033 0.3175 0.3175
Trypanosoma brucei PAB1-binding protein , putative 0.0015 0.009 0.0379
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0094 0.0094
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0011 0.0054 0.0094
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.033 0.3175 0.3172
Echinococcus granulosus caax prenyl protease 1 0.004 0.033 0.033
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0578 0.0578
Plasmodium falciparum basic transcription factor 3b, putative 0.0021 0.0148 0.0294
Loa Loa (eye worm) STAT protein 0.0095 0.0872 0.0868
Echinococcus multilocularis somatostatin receptor 0.0015 0.0094 0.0094
Echinococcus granulosus caspase 2 0.0018 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Schistosoma mansoni neurotransmitter gated ion channel 0.0145 0.1367 0.2758
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0021 0.015 0.015
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0028 0.0214 0.0214
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0145 0.1367 0.1367
Schistosoma mansoni ferritin 0.001 0.004 0.008
Loa Loa (eye worm) peptidase family M48 containing protein 0.004 0.033 0.0326
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0011 0.0054 0.0407
Trichomonas vaginalis heat shock protein, putative 0.0065 0.0576 0.1989
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0011 0.0054 0.005
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0042 0.0356 0.0352
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0094 0.0068
Chlamydia trachomatis hypothetical protein 0.0022 0.0162 0.0215
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0125 0.0746
Schistosoma mansoni nAChR subunit 0.0145 0.1367 0.2758
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0059 0.0055
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0125 0.0125
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.015 0.1008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0059 0.0055
Echinococcus multilocularis CAAX prenyl protease 2 0.0109 0.1006 0.1006
Brugia malayi sulfakinin receptor protein 0.0015 0.0094 0.009
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0094 0.009
Loa Loa (eye worm) Smad1 0.001 0.0036 0.0032
Trypanosoma cruzi transcription factor btf3, putative 0.0021 0.0148 0.0983
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.033 0.3175 0.3175
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0011 0.0054 0.0028
Brugia malayi cytoplasmic intermediate filament protein 0.0021 0.0147 0.0143
Leishmania major heat shock protein, putative 0.0043 0.0363 0.3239
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.1367 0.1364
Onchocerca volvulus 0.0015 0.0094 0.0068
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.001 0.004 0.0065
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.033 0.3175 0.3172
Schistosoma mansoni transcription factor LCR-F1 0.0063 0.0562 0.1134
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Brugia malayi STAT protein, DNA binding domain containing protein 0.0095 0.0872 0.0868
Entamoeba histolytica transcription factor BTF3, putative 0.0021 0.0148 0.0744
Echinococcus multilocularis glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Schistosoma mansoni ferritin light chain 0.001 0.004 0.008
Schistosoma mansoni myosin xvIII 0.0015 0.0094 0.0189
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0578 0.1147
Onchocerca volvulus 0.0015 0.0094 0.0068
Schistosoma mansoni opsin-like receptor 0.0015 0.0094 0.0189
Plasmodium falciparum protease, putative 0.0022 0.0162 0.0321
Loa Loa (eye worm) ACC-1 protein 0.033 0.3175 0.3172
Entamoeba histolytica hypothetical protein 0.0063 0.0562 0.2826
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.033 0.3175 0.3172
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0125 0.1018
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0059 0.012
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0011 0.0054 0.0188
Echinococcus granulosus nAChR subunit 0.0184 0.175 0.175
Echinococcus multilocularis dnaJ subfamily B 0.0246 0.2352 0.2352
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0059 0.0055
Brugia malayi neuropeptide F receptor 0.0015 0.0094 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0129 0.1204 0.1201
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.033 0.3175 0.3172
Echinococcus granulosus intermediate filament protein 0.0039 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0184 0.175 0.1746
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Trypanosoma brucei Heat shock protein 83, putative 0.0072 0.0645 0.6211
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0148 0.0511
Entamoeba histolytica hypothetical protein 0.0184 0.175 0.8792
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0094 0.009
Echinococcus granulosus glycine receptor subunit beta 0.033 0.3175 0.3175
Loa Loa (eye worm) hypothetical protein 0.0038 0.0318 0.0314
Echinococcus granulosus neuropeptide s receptor 0.0825 0.8027 0.8027
Leishmania major CAAX prenyl protease 1, putative,metallo-peptidase, Clan M-, Family M48 0.004 0.033 0.2897
Trypanosoma cruzi transcription factor btf3, putative 0.0021 0.0148 0.0983
Loa Loa (eye worm) TK/ALK protein kinase 0.0009 0.0033 0.0029
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0011 0.0054 0.0054
Echinococcus multilocularis lamin dm0 0.0039 0.0324 0.0324
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.015 0.1008
Schistosoma mansoni hypothetical protein 0.0009 0.0026 0.0053
Leishmania major basic transcription factor 3a, putative 0.0021 0.0148 0.0983
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0094 0.0094
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0116 0.0216
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0059 0.0033
Onchocerca volvulus 0.0038 0.0318 0.0292
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.015 0.1008
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0094 0.0094
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0578 0.1166
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0094 0.0094
Echinococcus multilocularis tar DNA binding protein 0.0129 0.1204 0.1204
Entamoeba histolytica hypothetical protein 0.0059 0.0525 0.2637
Brugia malayi Dopamine receptor protein 1 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0324 0.032
Toxoplasma gondii heat shock protein 90, putative 0.0072 0.0645 0.1281
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.033 0.3175 0.3172
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.001 0.004 0.028
Echinococcus multilocularis heat shock protein 90 0.0072 0.0645 0.0645
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0109 0.1006 0.2029
Brugia malayi MH2 domain containing protein 0.0141 0.1328 0.1325
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.1026 1 1
Echinococcus granulosus geminin 0.0444 0.4294 0.4294
Onchocerca volvulus 0.0015 0.0094 0.0068
Schistosoma mansoni nAChR subunit 0.033 0.3175 0.6404
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0011 0.0054 0.0094
Echinococcus granulosus neuropeptide receptor 0.0015 0.0094 0.0094
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0094 0.009
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0059 0.012
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.033 0.3175 0.6404
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0145 0.1367 0.1364
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0043 0.0363 0.0363
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0094 0.009
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Onchocerca volvulus Huntingtin homolog 0.007 0.0632 0.0608
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0148 0.0511
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.033 0.3175 0.3175
Echinococcus multilocularis MAM 0.0009 0.0033 0.0033
Onchocerca volvulus 0.0015 0.0094 0.0068
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.033 0.3175 0.6404
Echinococcus granulosus g protein coupled receptor 0.0015 0.0094 0.0094
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0145 0.1367 0.1364
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0011 0.0054 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.015 0.0519
Leishmania major hypothetical protein, conserved 0.0015 0.009 0.0379
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0125 0.0249
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0011 0.0054 0.0108
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0011 0.0054 0.0407
Loa Loa (eye worm) hypothetical protein 0.0018 0.0119 0.0115
Giardia lamblia Grp94/Hsp90 0.0065 0.0576 0.2895
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.1026 1 1
Schistosoma mansoni pyruvate dehydrogenase 0.0011 0.0054 0.011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0112
Echinococcus granulosus CAAX prenyl protease 2 0.0109 0.1006 0.1006
Echinococcus granulosus cpg binding protein 0.0018 0.0121 0.0121
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0014 0.008 0.008
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0011 0.0054 0.0094
Brugia malayi Serotonin receptor 0.0015 0.0094 0.009
Echinococcus granulosus somatostatin receptor 0.0015 0.0094 0.0094
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0043 0.0363 0.1822
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0094 0.009
Onchocerca volvulus 0.0512 0.4958 0.4944
Schistosoma mansoni ferritin 0.001 0.004 0.008
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Brugia malayi F/Y-rich N-terminus family protein 0.0007 0.0007 0.0003
Schistosoma mansoni hypothetical protein 0.0028 0.0214 0.0432
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis serotonin receptor 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0015 0.0094 0.0068
Brugia malayi Dopamine receptor 0.0015 0.0094 0.009
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0109 0.1006 1
Echinococcus multilocularis endoplasmin 0.0065 0.0576 0.0576
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0021 0.015 0.0756
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0155 0.1463 0.146
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.0356 0.0718
Brugia malayi TAR-binding protein 0.0129 0.1204 0.1201
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0022 0.0162 0.1329
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0094 0.0094
Schistosoma mansoni hypothetical protein 0.0018 0.0119 0.0239
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0125 0.0253
Echinococcus multilocularis ubiquitin specific protease 41 0.0021 0.015 0.015
Plasmodium vivax heat shock protein 86, putative 0.0072 0.0645 0.1281
Schistosoma mansoni endoplasmin 0.0072 0.0645 0.1302
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0094 0.0189
Schistosoma mansoni coup transcription factor 0.0012 0.0059 0.012
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0125 0.0746
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0116 0.0112
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0094 0.0189
Schistosoma mansoni hypothetical protein 0.0166 0.1565 0.3157
Plasmodium vivax ataxin-2 like protein, putative 0.0015 0.009 0.018
Mycobacterium ulcerans bacterioferritin BfrA 0.001 0.004 0.0065
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Schistosoma mansoni survival motor neuron protein 0.0051 0.0438 0.0884
Echinococcus multilocularis transcription factor btf3 0.0021 0.0148 0.0148
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0042 0.0356 0.0352
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0512 0.4958 1
Schistosoma mansoni acetylcholine receptor subunit beta 0.0145 0.1367 0.2758
Onchocerca volvulus 0.033 0.3175 0.3157
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0022 0.0162 0.1329
Brugia malayi G protein-coupled receptor 0.0015 0.0094 0.009
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0059 0.0059
Echinococcus granulosus TGF beta signal transducer SmadC 0.001 0.0036 0.0036
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0094 0.0094
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Loa Loa (eye worm) hypothetical protein 0.007 0.0632 0.0629
Echinococcus multilocularis TGF beta signal transducer SmadC 0.001 0.0036 0.0036
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0184 0.175 0.1746
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0011 0.0054 0.0188
Echinococcus granulosus ubiquitin specific protease 41 0.0021 0.015 0.015
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0011 0.0054 0.0029
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0011 0.0054 0.0094
Treponema pallidum exodeoxyribonuclease (exoA) 0.0014 0.008 0.0081
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0109 0.1006 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0059 0.0055
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0028 0.0214 0.021
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0094 0.0189
Brugia malayi Dopamine receptor protein 2 0.0015 0.0094 0.009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0038 0.0318 0.0318
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0094 0.009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0578 0.1134
Schistosoma mansoni cpg binding protein 0.0017 0.0111 0.0224
Mycobacterium tuberculosis Probable integral membrane protein 0.0022 0.0162 0.1329
Brugia malayi MH2 domain containing protein 0.001 0.0036 0.0032
Schistosoma mansoni smad1 5 8 and 0.001 0.0036 0.0073
Schistosoma mansoni ferritin 0.001 0.004 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Schistosoma mansoni DNA topoisomerase II 0.0011 0.0054 0.011
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.0015 0.0094 0.0189
Trypanosoma cruzi heat shock protein, putative 0.0043 0.0363 0.3239
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.1367 0.1364
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0019 0.0126 0.0126
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0116 0.0647
Echinococcus granulosus GPCR family 2 0.0028 0.0214 0.0214
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0043 0.0363 0.0337
Brugia malayi ecdysteroid receptor 0.0012 0.0059 0.0055
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Loa Loa (eye worm) hypothetical protein 0.1026 1 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0125 0.0125
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.015 0.1008
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0019 0.0126 0.0126
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0014 0.008 0.0076
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0094 0.0094
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0059 0.012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0125 0.0746
Loa Loa (eye worm) GABA receptor subunit 0.0184 0.175 0.1746
Loa Loa (eye worm) hypothetical protein 0.0011 0.0054 0.005
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0011 0.0054 0.0094
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0109 0.1006 0.3472
Mycobacterium tuberculosis Conserved protein 0.0011 0.0054 0.0407
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.0119 0.0239
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0065 0.0576 0.4903
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0094 0.0189
Giardia lamblia DNA repair protein RAD52 0.0209 0.199 1
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0054 0.0108
Echinococcus granulosus orexin receptor type 2 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0011 0.0054 0.005
Schistosoma mansoni apoferritin-2 0.001 0.004 0.008
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0094 0.009
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Schistosoma mansoni Smad4 0.001 0.0036 0.0073
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0094 0.0189
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.033 0.3175 0.3175
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Trypanosoma cruzi heat shock protein 85, putative 0.006 0.0533 0.5029
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.033 0.3175 0.3175
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.006 0.053 0.0526
Brugia malayi nuclear hormone receptor 0.0012 0.0059 0.0055
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.033 0.3175 0.3175
Brugia malayi Cation transporter family protein 0.0512 0.4958 0.4956
Onchocerca volvulus 0.0015 0.0094 0.0068
Echinococcus multilocularis smad 0.001 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi Hsp90 protein 0.0043 0.0363 0.0359
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) heat shock protein 90 0.0072 0.0645 0.0642
Trypanosoma brucei heat shock protein 90, putative 0.0072 0.0645 0.6211
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0248 0.2375 0.2372
Schistosoma mansoni hypothetical protein 0.0028 0.0214 0.0432
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0014 0.008 0.0402
Onchocerca volvulus Putative nachr subunit 0.1026 1 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0008 0.0008
Echinococcus granulosus smad 0.001 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Schistosoma mansoni hypothetical protein 0.0009 0.0033 0.0066
Plasmodium vivax protease, putative 0.0022 0.0162 0.0321
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0013 0.0072 0.0558
Brugia malayi hypothetical protein 0.0015 0.009 0.0087
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0094 0.0094
Brugia malayi SEA domain containing protein 0.0009 0.0026 0.0022
Trypanosoma brucei heat shock protein 90, putative 0.0072 0.0645 0.6211
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0994 0.3432
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Echinococcus granulosus fmrfamide receptor 0.0015 0.0094 0.0094
Onchocerca volvulus 0.0018 0.0119 0.0093
Echinococcus granulosus dnaJ subfamily B 0.0246 0.2352 0.2352
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0042 0.0356 0.0356
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.033 0.3175 0.3172
Echinococcus multilocularis glycine receptor subunit beta 0.033 0.3175 0.3175
Trypanosoma brucei transcription factor BTF3, putative 0.0021 0.0148 0.0983
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.1367 0.1364
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0116 0.0937
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0145 0.1367 0.1367
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0011 0.0054 0.0054
Echinococcus multilocularis X box binding protein 1 0.0166 0.1565 0.1565
Brugia malayi hypothetical protein 0.007 0.0632 0.0629
Echinococcus granulosus tar DNA binding protein 0.0129 0.1204 0.1204
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Onchocerca volvulus 0.0015 0.0094 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0059 0.0055
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni smad1 5 8 and 0.001 0.0036 0.0073
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0094 0.0094
Loa Loa (eye worm) RNA binding protein 0.0129 0.1204 0.1201
Mycobacterium ulcerans two component sensor kinase MprB 0.0011 0.0054 0.0094
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.1026 1 1
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0065 0.0576 0.5483
Schistosoma mansoni biogenic amine receptor 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Echinococcus multilocularis caspase 2 0.0018 0.0119 0.0119
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0011 0.0054 0.0188
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0018 0.0116 0.0216
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.008 0.0159
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0059 0.012
Brugia malayi Cation transporter family protein 0.033 0.3175 0.3172
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0512 0.4958 1
Plasmodium falciparum heat shock protein 90 0.0072 0.0645 0.1281
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Toxoplasma gondii heat shock protein HSP90 0.0072 0.0645 0.1281
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0011 0.0054 0.0094
Brugia malayi nuclear receptor NHR-88 0.0012 0.0059 0.0055
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.0356 0.0718
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Loa Loa (eye worm) TOPoisomerase family member 0.0011 0.0054 0.005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0042 0.0356 0.0356
Onchocerca volvulus 0.033 0.3175 0.3157
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0094 0.0094
Toxoplasma gondii Hsp90 domain-containing protein 0.0209 0.1989 0.3947
Schistosoma mansoni ferritin light chain 0.001 0.004 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0148 0.0511
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.015 0.0519
Loa Loa (eye worm) TAR-binding protein 0.0129 0.1204 0.1201
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Mycobacterium ulcerans heat shock protein 90 0.0065 0.0576 0.1131
Schistosoma mansoni hypothetical protein 0.0444 0.4294 0.8662
Trypanosoma cruzi CAAX prenyl protease 1, putative 0.004 0.033 0.2897
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0011 0.0054 0.0094
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0043 0.0363 0.0363
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0094 0.0094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0125 0.0125
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0059 0.0059
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0125 0.0121
Loa Loa (eye worm) hypothetical protein 0.0018 0.0119 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0059 0.0055
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0094 0.0189
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0094 0.009
Onchocerca volvulus 0.0145 0.1367 0.1344
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0059 0.0059
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0094 0.0094
Trypanosoma brucei CAAX amino terminal protease, putative 0.0109 0.1006 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0042 0.0356 0.0356
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0059 0.0055
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0009 0.0033 0.0029
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0059 0.0055
Entamoeba histolytica hypothetical protein 0.0063 0.0562 0.2826
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0438 0.0435
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.009 0.018
Plasmodium vivax endoplasmin, putative 0.0072 0.0645 0.1281
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.5037 1
Echinococcus multilocularis glycine receptor subunit beta 0.033 0.3175 0.3175
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.033 0.3175 0.3172
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.033 0.3175 0.3175
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0116 0.0216
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0007 0.0009 0.0009
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Toxoplasma gondii heat shock protein 75, putative 0.0043 0.0363 0.072
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0063 0.0562 0.0562
Trypanosoma cruzi heat shock protein 85, putative 0.0072 0.0645 0.6211
Echinococcus granulosus histone lysine methyltransferase setb 0.0038 0.0318 0.0318
Echinococcus granulosus glycine receptor subunit beta 0.033 0.3175 0.3175
Plasmodium vivax heat shock protein 90, putative 0.0043 0.0363 0.072
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0094 0.0094
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0094 0.0189
Schistosoma mansoni opsin-like receptor 0.0015 0.0094 0.0189
Echinococcus granulosus sex peptide receptor 0.0015 0.0094 0.0094
Echinococcus granulosus heat shock protein 90 0.0072 0.0645 0.0645
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0318 0.0641
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0145 0.1367 0.1367
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0059 0.0525 0.2637
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.0125 0.1167 1
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0011 0.0054 0.0407
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0059 0.0033
Echinococcus granulosus X box binding protein 1 0.0166 0.1565 0.1565
Treponema pallidum hypothetical protein 0.0022 0.0162 0.0244
Brugia malayi Cation transporter family protein 0.033 0.3175 0.3172
Plasmodium vivax acyl-CoA synthetase, putative 0.0013 0.0072 0.0143
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0059 0.0059
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Schistosoma mansoni amine GPCR 0.0015 0.0094 0.0189
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0094 0.0094
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0094 0.009
Loa Loa (eye worm) ACC-1 protein 0.033 0.3175 0.3172
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0014 0.008 0.008
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0094 0.0189
Mycobacterium tuberculosis Bacterioferritin BfrB 0.001 0.004 0.028
Loa Loa (eye worm) hypothetical protein 0.0015 0.009 0.0087
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0011 0.0054 0.0094
Trypanosoma cruzi heat shock protein 90, putative 0.0072 0.0645 0.6211
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0011 0.0054 0.0054
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.008 0.0276
Mycobacterium leprae Probable two-component sensor kinase 0.0011 0.0054 0.0094
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.5037 1
Mycobacterium tuberculosis Possible two component sensor kinase 0.0011 0.0054 0.0407
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0059 0.012
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0088 0.0802 0.0798
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0014 0.008 0.0269
Loa Loa (eye worm) transcription factor SMAD2 0.0141 0.1328 0.1325
Brugia malayi Melatonin receptor type 1A 0.0015 0.0094 0.009
Loa Loa (eye worm) MH2 domain-containing protein 0.0141 0.1328 0.1325
Plasmodium falciparum DNA topoisomerase 2 0.0011 0.0054 0.0108
Echinococcus multilocularis nAChR subunit 0.033 0.3175 0.3175
Schistosoma mansoni ap endonuclease 0.0014 0.008 0.0161
Onchocerca volvulus Huntingtin homolog 0.007 0.0632 0.0608
Echinococcus multilocularis ferritin 0.001 0.004 0.004
Trypanosoma cruzi heat shock protein 90, putative 0.006 0.0533 0.5029
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0112
Loa Loa (eye worm) hypothetical protein 0.007 0.0632 0.0629
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0094 0.0094
Brugia malayi GnHR receptor homolog 0.0015 0.0094 0.009
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0011 0.0054 0.0094
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0094 0.0094
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0094 0.0094
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0184 0.175 0.3529
Entamoeba histolytica hypothetical protein 0.0063 0.0562 0.2826
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0011 0.0054 0.0028
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0094 0.0094
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0028 0.0214 0.0214
Loa Loa (eye worm) intermediate filament protein 0.0039 0.0324 0.032
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0125 0.0249
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0268 0.2244
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0094 0.0094
Giardia lamblia Heat shock protein HSP 90-alpha 0.0072 0.0645 0.3243
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.0036 0.0032
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0094 0.0094
Brugia malayi heat shock protein 90 0.0072 0.0645 0.0642
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0065 0.0497
Toxoplasma gondii CAAX amino terminal protease family protein 0.0022 0.0162 0.0321
Onchocerca volvulus 0.0051 0.0438 0.0413
Schistosoma mansoni farnesylated-protein converting enzyme 1 (M48 family) 0.004 0.033 0.0666
Entamoeba histolytica CAAX prenyl protease, putative 0.004 0.033 0.1658
Schistosoma mansoni hypothetical protein 0.0015 0.0094 0.0189
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.004 0.033 0.114
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0025
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0059 0.012
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Schistosoma mansoni hypothetical protein 0.0063 0.0562 0.1134
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Plasmodium vivax heat shock protein, putative 0.0209 0.1989 0.3947
Echinococcus multilocularis expressed protein 0.001 0.004 0.004
Brugia malayi exodeoxyribonuclease III family protein 0.0014 0.008 0.0076
Brugia malayi steroid hormone receptor 0.0012 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0094 0.0094
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0094 0.0094
Trichomonas vaginalis glucosylceramidase, putative 0.0155 0.1463 0.5053
Loa Loa (eye worm) latrophilin receptor protein 2 0.0028 0.0214 0.021
Brugia malayi Serotonin receptor 0.0015 0.0094 0.009
Brugia malayi hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi beta-NAC-like protein 0.0021 0.0148 0.0144
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0059 0.012
Schistosoma mansoni hypothetical protein 0.0444 0.4294 0.8662
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0039 0.0324 0.032
Echinococcus granulosus survival motor neuron protein 1 0.0248 0.2375 0.2375
Brugia malayi G-protein coupled receptor 0.0015 0.0094 0.009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0063 0.0562 0.0562
Brugia malayi G-protein coupled receptor 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Brugia malayi Protein kinase domain containing protein 0.0009 0.0033 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0059 0.0059
Brugia malayi RNA binding protein 0.0129 0.1204 0.1201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0009 0.0026 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0059 0.0059
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0125 0.0746
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus heat shock protein 0.0072 0.0645 0.0645
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0006 0.0004 0.0004
Echinococcus multilocularis mothers against decapentaplegic 5 0.001 0.0036 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0015 0.009 0.0379
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0318 0.0641
Plasmodium falciparum DNA gyrase subunit B 0.0011 0.0054 0.0108
Schistosoma mansoni lamin 0.0039 0.0324 0.0653
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0028 0.0214 0.0214
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0088 0.0802 0.0798
Schistosoma mansoni hypothetical protein 0.006 0.053 0.1068
Mycobacterium ulcerans integral membrane protein 0.0022 0.0162 0.0307
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0145 0.1367 0.1364
Brugia malayi Intermediate filament tail domain containing protein 0.0039 0.0324 0.032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Trypanosoma cruzi Heat shock protein 83, putative 0.0072 0.0645 0.6211
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0094 0.0189
Echinococcus granulosus serotonin receptor 0.0015 0.0094 0.0094
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0094 0.0189
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.033 0.3175 0.3172
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0209 0.199 1
Onchocerca volvulus 0.0015 0.0094 0.0068
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0994 0.3432
Trichomonas vaginalis heat shock protein, putative 0.0072 0.0645 0.2228
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0021 0.015 0.0303
Echinococcus granulosus lamin 0.0039 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0009 0.0033 0.0029
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0094 0.0094
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.033 0.3175 0.3172
Schistosoma mansoni hypothetical protein 0.0009 0.0033 0.0066
Echinococcus multilocularis cpg binding protein 0.0018 0.0121 0.0121
Schistosoma mansoni smad 0.001 0.0036 0.0073
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0094 0.009
Echinococcus granulosus Smad4 0.001 0.0036 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Brugia malayi Muscle positioning protein 4 0.0009 0.0026 0.0022
Toxoplasma gondii CAAX metallo endopeptidase 0.004 0.033 0.0655
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0094 0.0094
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0014 0.008 0.0145
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0011 0.0054 0.0094
Brugia malayi RE15519p 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Plasmodium falciparum heat shock protein 90, putative 0.0038 0.0319 0.0634
Loa Loa (eye worm) heat shock protein 75 0.0043 0.0363 0.0359
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Echinococcus multilocularis sex peptide receptor 0.0015 0.0094 0.0094
Entamoeba histolytica acyl-CoA synthetase, putative 0.0018 0.0116 0.0583
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0059 0.012
Echinococcus granulosus ferritin 0.001 0.004 0.004
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0021 0.015 0.0303
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.015 0.0756
Echinococcus multilocularis lamin 0.0039 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus mothers against decapentaplegic 5 0.001 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0102 0.094 0.3246
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0028 0.0214 0.0214
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.5037 1
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0094 0.0094
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.006 0.0533 0.0533
Brugia malayi MH2 domain containing protein 0.001 0.0036 0.0032
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0125 0.0249
Brugia malayi neuropeptide F receptor 0.0015 0.0094 0.009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0059 0.0055
Schistosoma mansoni heat shock protein 0.0072 0.0645 0.1302
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0065 0.0497
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.0036 0.0032
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0014 0.008 0.0627
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0094 0.0189
Echinococcus granulosus apoptotic protease activating factor 1 0.0018 0.0119 0.0119
Onchocerca volvulus 0.0015 0.0094 0.0068
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0011 0.0054 0.0407
Onchocerca volvulus 0.0012 0.0059 0.0033
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0007 0.0009 0.0009
Entamoeba histolytica heat shock protein 90, putative 0.0072 0.0645 0.3243
Schistosoma mansoni cpg binding protein 0.0018 0.0121 0.0244
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0184 0.175 0.1746
Brugia malayi intermediate filament protein 0.0039 0.0324 0.032
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0059 0.0055
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0059 0.0059
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0094 0.009
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0116 0.0216
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1204 0.2429
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0059 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0125 0.0249
Echinococcus multilocularis glycine receptor subunit alpha 1 0.033 0.3175 0.3175
Brugia malayi Smad1 0.001 0.0036 0.0032
Onchocerca volvulus 0.0145 0.1367 0.1344
Brugia malayi larval opioid receptor 0.0015 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0021 0.015 0.0146
Onchocerca volvulus 0.0184 0.175 0.1728
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi hypothetical protein 0.0009 0.0033 0.0029
Brugia malayi isocitrate dehydrogenase 0.0019 0.0125 0.0121
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0578 0.1134
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0094 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0059 0.0055
Echinococcus granulosus allatostatin A receptor 0.0015 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Onchocerca volvulus 0.0145 0.1367 0.1344
Mycobacterium ulcerans hypothetical protein 0.0022 0.0162 0.0307
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0578 0.0578
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Mycobacterium ulcerans hypothetical protein 0.0018 0.0116 0.0216
Trichomonas vaginalis DNA topoisomerase II, putative 0.0011 0.0054 0.0188
Schistosoma mansoni transcription factor btf3 0.0021 0.0148 0.0298
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0112
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0125 0.0746
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Loa Loa (eye worm) hypothetical protein 0.0013 0.0072 0.0068
Brugia malayi excitatory GABA receptor EXP-1A 0.033 0.3175 0.3172
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0011 0.0054 0.0407
Leishmania major heat shock protein 83-1 0.0072 0.0645 0.6211
Loa Loa (eye worm) hypothetical protein 0.0009 0.0026 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0094 0.0189
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.009
Brugia malayi Endoplasmin precursor 0.0072 0.0645 0.0642
Brugia malayi Pre-SET motif family protein 0.0265 0.2538 0.2535
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.033 0.3175 0.6404
Echinococcus granulosus MAM 0.0009 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0184 0.175 0.1746
Schistosoma mansoni opsin-like receptor 0.0015 0.0094 0.0189
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0065 0.0497
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0011 0.0054 0.0407
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0094 0.009
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0094 0.0094
Entamoeba histolytica DNA topoisomerase II, putative 0.0011 0.0054 0.0274
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0184 0.175 0.3529
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0116 0.0647
Brugia malayi Latrophilin receptor protein 2 0.0028 0.0214 0.021
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0094 0.0094
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0094 0.0094
Schistosoma mansoni ferritin 0.001 0.004 0.008
Echinococcus granulosus nAChR subunit 0.033 0.3175 0.3175
Loa Loa (eye worm) hypothetical protein 0.0145 0.1367 0.1364
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0145 0.1367 0.1367
Echinococcus granulosus g protein coupled receptor 0.0015 0.0094 0.0094
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0011 0.0054 0.0407
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.0242
Toxoplasma gondii LsmAD domain-containing protein 0.0015 0.009 0.018
Brugia malayi Probable DNA topoisomerase II 0.0011 0.0054 0.005
Giardia lamblia Heat shock protein HSP 90-alpha 0.006 0.0533 0.2678
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0094 0.0094
Brugia malayi Pre-SET motif family protein 0.0038 0.0318 0.0314
Loa Loa (eye worm) hypothetical protein 0.033 0.3175 0.3172
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0116 0.0216
Brugia malayi hypothetical protein 0.0015 0.0094 0.009
Schistosoma mansoni neurotransmitter gated ion channel 0.0145 0.1367 0.2758
Trypanosoma brucei heat shock protein, putative 0.0072 0.0645 0.6211

Activities

Activity type Activity value Assay description Source Reference
Log IC50 (binding) = 5.62 Inhibitory concentration against DOXP reductoisomerase ChEMBL. 15887963

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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