Detailed information for compound 372730

Basic information

Technical information
  • TDR Targets ID: 372730
  • Name: 6-cyclopentyl-6-[2-(3-propan-2-ylphenyl)ethyl ]oxane-2,4-dione
  • MW: 328.445 | Formula: C21H28O3
  • H donors: 0 H acceptors: 2 LogP: 4.92 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CC(=O)OC(C1)(CCc1cccc(c1)C(C)C)C1CCCC1
  • InChi: 1S/C21H28O3/c1-15(2)17-7-5-6-16(12-17)10-11-21(18-8-3-4-9-18)14-19(22)13-20(23)24-21/h5-7,12,15,18H,3-4,8-11,13-14H2,1-2H3
  • InChiKey: PBCKOBZTPBNOBL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 6-cyclopentyl-6-[2-(3-isopropylphenyl)ethyl]tetrahydropyran-2,4-dione
  • 6-cyclopentyl-6-(2-m-cumenylethyl)tetrahydropyran-2,4-quinone
  • 6-cyclopentyl-6-[2-(3-isopropylphenyl)ethyl]tetrahydropyran-2,4-quinone

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Hepatitis C virus Hepatitis C virus NS5B RNA-dependent RNA polymerase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Giardia lamblia Rrm3p helicase Get druggable targets OG5_128192 All targets in OG5_128192
Trypanosoma congolense DNA repair and recombination helicase protein PIF6 Get druggable targets OG5_128192 All targets in OG5_128192
Trypanosoma congolense DNA repair and recombination protein, mitochondrial precursor, putative Get druggable targets OG5_128192 All targets in OG5_128192
Entamoeba histolytica DNA repair and recombination protein, putative Get druggable targets OG5_128192 All targets in OG5_128192
Trypanosoma brucei gambiense DNA repair and recombination helicase protein PIF1, putative,DNA repair and recombination protein, mitochondrial precursor, puta Get druggable targets OG5_128192 All targets in OG5_128192
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative Get druggable targets OG5_128192 All targets in OG5_128192
Schistosoma mansoni hypothetical protein Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania infantum PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania infantum PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative Get druggable targets OG5_128192 All targets in OG5_128192
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_128192 All targets in OG5_128192
Candida albicans similar to PIF1 DNA helicase Get druggable targets OG5_128192 All targets in OG5_128192
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative Get druggable targets OG5_128192 All targets in OG5_128192
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative Get druggable targets OG5_128192 All targets in OG5_128192
Candida albicans DNA helicase Get druggable targets OG5_128192 All targets in OG5_128192
Schistosoma japonicum ko:K01529 PIF1 5'-to-3' DNA helicase [EC:3.6.1.-], putative Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania mexicana PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania braziliensis PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania braziliensis PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania mexicana PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania donovani PIF1 helicase-like protein, putative Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania donovani PIF1 helicase-like protein, putative Get druggable targets OG5_128192 All targets in OG5_128192
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 Get druggable targets OG5_128192 All targets in OG5_128192
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 Get druggable targets OG5_128192 All targets in OG5_128192
Candida albicans similar to putative DNA helicase involved in repair and recombination of mitochondrial DNA that also plays a role in (nuclear) c Get druggable targets OG5_128192 All targets in OG5_128192
Entamoeba histolytica hypothetical protein, conserved Get druggable targets OG5_128192 All targets in OG5_128192
Echinococcus multilocularis ATP dependent DNA helicase PIF1 Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative Get druggable targets OG5_128192 All targets in OG5_128192
Echinococcus granulosus ATP dependent DNA helicase PIF1 Get druggable targets OG5_128192 All targets in OG5_128192
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative Get druggable targets OG5_128192 All targets in OG5_128192
Trypanosoma brucei gambiense DNA repair and recombination helicase protein PIF1, putative,DNA repair and recombination protein, mitochondrial precursor, puta Get druggable targets OG5_128192 All targets in OG5_128192
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.0017 0.0024
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0161 0.0649
Echinococcus granulosus neuropeptide FF receptor 2 0.0039 0.0317 0.0428
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0416 0.0416
Schistosoma mansoni neuropeptide receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.0317 0.0317
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0122 0.3806
Schistosoma mansoni histamine h1 receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) abnormal epIthelia family member 0.0025 0.0154 0.0401
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis fmrfamide receptor 0.0039 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Schistosoma mansoni zinc finger protein 0.0023 0.013 0.0176
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0039 0.0317 0.0317
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0086 0.0345
Loa Loa (eye worm) hypothetical protein 0.0021 0.0115 0.03
Echinococcus granulosus neuropeptide receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis RUN 0.0022 0.0122 0.0122
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0134 0.057
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0134 0.0438
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0013 0.0017 0.0024
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0134 0.0639
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0048 0.0416 0.1084
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0178 0.5569
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0317 0.0428
Brugia malayi Cation transporter family protein 0.0019 0.0086 0.0345
Schistosoma mansoni hypothetical protein 0.0274 0.2959 0.3998
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0569 0.2754
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0334 0.1175
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0013 0.0017 0.0493
Loa Loa (eye worm) hypothetical protein 0.0039 0.0315 0.0822
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0123 0.3798
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0086 0.0345
Echinococcus multilocularis neuropeptide Y receptor 0.0039 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0021 0.0115 0.03
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0566 0.0765
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0161 0.0218
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0039 0.0317 0.1277
Loa Loa (eye worm) hypothetical protein 0.0053 0.0469 0.1224
Trypanosoma cruzi Aminopeptidase M1, putative 0.0013 0.0017 0.0493
Echinococcus multilocularis lamin dm0 0.0084 0.0822 0.0822
Onchocerca volvulus 0.0039 0.0317 0.1116
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0013 0.0017 0.0493
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0115 0.0155
Brugia malayi photoreceptor-specific nuclear receptor 0.0048 0.0416 0.1675
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0238 0.2545 0.3439
Brugia malayi GnHR receptor homolog 0.0039 0.0317 0.1277
Echinococcus granulosus fmrfamide receptor 0.0039 0.0317 0.0428
Onchocerca volvulus 0.0039 0.0317 0.1116
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Onchocerca volvulus 0.0015 0.004 0.0142
Brugia malayi Heterochromatin protein 1 0.0068 0.0635 0.256
Schistosoma mansoni neuropeptide receptor 0.0039 0.0317 0.0428
Toxoplasma gondii PAN domain-containing protein 0.0015 0.004 0.0195
Toxoplasma gondii PAN domain-containing protein 0.0015 0.004 0.0195
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Onchocerca volvulus 0.0023 0.0134 0.0472
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0086 0.0116
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.004 0.0105
Schistosoma mansoni nAChR subunit 0.0019 0.0086 0.0116
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.032 0.1305
Echinococcus granulosus serotonin receptor 0.0039 0.0317 0.0428
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0115 0.0155
Echinococcus multilocularis g protein coupled receptor 0.0039 0.0317 0.0317
Brugia malayi Dopamine receptor protein 2 0.0039 0.0317 0.1277
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0134 0.0378
Echinococcus multilocularis neuropeptides capa receptor 0.0039 0.0317 0.0317
Onchocerca volvulus 0.0039 0.0317 0.1116
Schistosoma mansoni neuropeptide F-like receptor 0.0039 0.0317 0.0428
Brugia malayi AKH receptor 0.0039 0.0317 0.1277
Trichomonas vaginalis rotamase, putative 0.0037 0.0293 0.0956
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0048 0.0416 0.0562
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0115 0.0155
Schistosoma mansoni rab6-interacting 0.0022 0.0122 0.0165
Toxoplasma gondii hypothetical protein 0.0015 0.004 0.0195
Echinococcus multilocularis aminopeptidase N 0.0013 0.0017 0.0017
Brugia malayi intermediate filament protein 0.0084 0.0822 0.3313
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0317 0.0317
Onchocerca volvulus 0.0019 0.0086 0.0302
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0416 0.0562
Schistosoma mansoni laminin gamma-3 chain 0.0025 0.0154 0.0208
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0317 0.0317
Schistosoma mansoni hypothetical protein 0.0022 0.0122 0.0165
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0086 0.0116
Brugia malayi Tachykinin-like peptides receptor 99D 0.0039 0.0317 0.1277
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3063 1
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0115 0.0155
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0023 0.0134 0.035
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus granulosus g protein coupled receptor 0.0039 0.0317 0.0428
Schistosoma mansoni RAR-like nuclear receptor 0.0048 0.0416 0.0562
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0034 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0021 0.0115 0.03
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0039 0.0317 0.0428
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.1433 0.6849
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0048 0.0416 0.0562
Schistosoma mansoni nAChR subunit 0.0019 0.0086 0.0116
Echinococcus multilocularis g protein coupled receptor 0.0039 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Schistosoma mansoni intermediate filament proteins 0.0084 0.0822 0.1111
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0081 0.0265
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0179
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.013 0.0176
Onchocerca volvulus 0.0015 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0025 0.0154 0.0401
Toxoplasma gondii PAN domain-containing protein 0.0015 0.004 0.0195
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0039 0.0317 0.1277
Echinococcus granulosus alpha 1A adrenergic receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0234 0.0611
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0086 0.0345
Echinococcus granulosus neuropeptide Y receptor 0.0039 0.0317 0.0428
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.013 0.0526
Echinococcus multilocularis tumor protein p63 0.0361 0.3932 0.3932
Echinococcus granulosus FTZ F1 alpha 0.0048 0.0416 0.0562
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0134 0.0438
Brugia malayi laminin alpha chain 0.0025 0.0154 0.0619
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0105
Toxoplasma gondii microneme protein MIC17B 0.0015 0.004 0.0195
Echinococcus granulosus slit 2 protein 0.0025 0.0154 0.0208
Schistosoma mansoni hypothetical protein 0.0034 0.0253 0.0342
Onchocerca volvulus 0.0039 0.0317 0.1116
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0086 0.0116
Schistosoma mansoni steroid hormone receptor ad4bp 0.0048 0.0416 0.0562
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0134 0.057
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0013 0.0017 0.0546
Echinococcus granulosus hypothetical protein 0.0039 0.0317 0.0428
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0048 0.0416 0.0416
Echinococcus granulosus ecdysone induced protein 78C 0.0048 0.0416 0.0562
Brugia malayi PXA domain containing protein 0.0021 0.0115 0.0463
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.013 0.0526
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Brugia malayi G-protein coupled receptor 0.0039 0.0317 0.1277
Echinococcus granulosus G protein coupled receptor 139 0.0039 0.0317 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0115 0.0375
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0039 0.0317 0.0428
Onchocerca volvulus 0.0039 0.0317 0.1116
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0086 0.0345
Echinococcus multilocularis neuropeptide receptor 0.0039 0.0317 0.0317
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.004 0.0105
Echinococcus multilocularis cpg binding protein 0.0034 0.0255 0.0255
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0131 0.1353 0.1353
Toxoplasma gondii aminopeptidase n, putative 0.0013 0.0017 0.0085
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0086 0.0116
Echinococcus multilocularis microtubule associated protein 2 0.067 0.74 0.74
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.032 0.129
Trichomonas vaginalis set domain proteins, putative 0.0264 0.2841 0.9276
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Schistosoma mansoni amine GPCR 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0046
Schistosoma mansoni hypothetical protein 0.0039 0.0317 0.0428
Mycobacterium ulcerans aldehyde dehydrogenase 0.0195 0.2065 1
Loa Loa (eye worm) hypothetical protein 0.0352 0.3837 1
Echinococcus multilocularis somatostatin receptor 0.0039 0.0317 0.0317
Brugia malayi hypothetical protein 0.0109 0.1103 0.4444
Brugia malayi conserved hypotetical protein 0.0023 0.013 0.0526
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0115 0.0463
Onchocerca volvulus 0.0039 0.0317 0.1116
Loa Loa (eye worm) hypothetical protein 0.0021 0.0115 0.03
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Onchocerca volvulus 0.0039 0.0317 0.1116
Echinococcus granulosus aminopeptidase N 0.0013 0.0017 0.0024
Onchocerca volvulus 0.0039 0.0317 0.1116
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0105
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0013 0.0017 0.0546
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0086 0.0345
Schistosoma mansoni amine GPCR 0.0039 0.0317 0.0428
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0036 0.0283 0.8827
Brugia malayi tailless protein 0.0023 0.013 0.0526
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0123 0.0596
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.0017 0.0024
Brugia malayi hypothetical protein 0.0027 0.0178 0.0718
Brugia malayi neuropeptide F receptor 0.0039 0.0317 0.1277
Onchocerca volvulus 0.0032 0.0234 0.0824
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0115 0.0155
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0013 0.0017 0.0073
Echinococcus granulosus expressed protein 0.0415 0.4536 0.6129
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0178 0.5544
Echinococcus granulosus tachykinin peptides receptor 99D 0.0039 0.0317 0.0428
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0566 0.0765
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0086 0.0345
Echinococcus granulosus g-protein coupled receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0038 0.0302 0.0786
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0115 0.0155
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus multilocularis geminin 0.0188 0.1991 0.1991
Onchocerca volvulus 0.0045 0.0381 0.1339
Brugia malayi hypothetical protein 0.0023 0.013 0.0526
Schistosoma mansoni rab6-interacting 0.0022 0.0122 0.0165
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0069 0.0053
Echinococcus granulosus pikachurin 0.0025 0.0154 0.0208
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0308 0.0308
Brugia malayi hypothetical protein 0.0013 0.0017 0.007
Schistosoma mansoni lipoxygenase 0.0022 0.0122 0.0165
Loa Loa (eye worm) hypothetical protein 0.0048 0.0416 0.1084
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0126 0.1293 0.1747
Schistosoma mansoni nAChR subunit 0.0019 0.0086 0.0116
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.013 0.4036
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0115 0.0155
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0039 0.0317 0.1116
Echinococcus multilocularis nAChR subunit 0.0019 0.0086 0.0086
Brugia malayi G protein-coupled receptor F59B2.13 0.0039 0.0317 0.1277
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0256 0.0346
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0048 0.0416 0.0416
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0086 0.0086
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0039 0.0317 0.1277
Echinococcus granulosus neuropeptide Y receptor 0.0039 0.0317 0.0428
Brugia malayi Dopamine receptor 0.0039 0.0317 0.1277
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.032 0.1045
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0115 0.0463
Echinococcus multilocularis chromobox protein 1 0.0068 0.0635 0.0635
Onchocerca volvulus 0.0039 0.0317 0.1116
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0086 0.0345
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0048 0.0416 0.1084
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0046
Onchocerca volvulus 0.0039 0.0317 0.1116
Schistosoma mansoni lamin 0.0084 0.0822 0.1111
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0048 0.0416 0.0562
Onchocerca volvulus 0.0015 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Onchocerca volvulus 0.0013 0.0017 0.0062
Echinococcus multilocularis ecdysone induced protein 78C 0.0048 0.0416 0.0416
Brugia malayi RNA binding protein 0.0061 0.0566 0.2282
Echinococcus multilocularis serotonin receptor 0.0039 0.0317 0.0317
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.032 1
Echinococcus multilocularis expressed protein 0.0037 0.0293 0.0293
Onchocerca volvulus 0.003 0.021 0.0737
Loa Loa (eye worm) hypothetical protein 0.0021 0.0115 0.03
Schistosoma mansoni nAChR subunit 0.0019 0.0086 0.0116
Echinococcus multilocularis neuropeptide FF receptor 2 0.0039 0.0317 0.0317
Toxoplasma gondii peptidylprolyl isomerase 0.0036 0.0283 0.137
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Onchocerca volvulus 0.0015 0.004 0.0142
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.0317 0.0428
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0134 0.057
Onchocerca volvulus 0.0022 0.0122 0.0429
Loa Loa (eye worm) G-protein coupled receptor 0.0039 0.0317 0.0826
Mycobacterium ulcerans aldehyde dehydrogenase 0.0195 0.2065 1
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0154 0.0154
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.032 0.032
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0048 0.0416 0.1084
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0086 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0048 0.0416 0.1675
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Brugia malayi putative neuropeptide receptor NPR1 0.0039 0.0317 0.1277
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0048 0.0416 0.1675
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0302 0.0984
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0115 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0048 0.0416 0.1675
Schistosoma mansoni opsin-like receptor 0.0039 0.0317 0.0428
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.013 0.0176
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0317 0.0428
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0566 0.0765
Entamoeba histolytica recQ family DNA helicase 0.0011 0.0002 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0308 0.0416
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0013 0.0017 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0048 0.0416 0.1675
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0081 0.0265
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0036 0.0283 0.136
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0122 0.0122
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0195 0.2065 1
Schistosoma mansoni chromobox protein 0.0068 0.0635 0.0859
Echinococcus granulosus somatostatin receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis neuropeptides capa receptor 0.0039 0.0317 0.0317
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0086 0.0116
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0134 0.057
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0123 0.0496
Trypanosoma brucei Aminopeptidase M1, putative 0.0013 0.0017 0.0473
Echinococcus multilocularis G protein coupled receptor 139 0.0039 0.0317 0.0317
Onchocerca volvulus 0.0084 0.0822 0.2895
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0161 0.0161
Brugia malayi hypothetical protein 0.0021 0.0115 0.0463
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Loa Loa (eye worm) hypothetical protein 0.0023 0.0134 0.035
Brugia malayi RE15519p 0.0039 0.0317 0.1277
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0086 0.0116
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Onchocerca volvulus Putative nachr subunit 0.0019 0.0086 0.0302
Schistosoma mansoni thyroid hormone receptor 0.0322 0.3499 0.4728
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0115 0.0115
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.0017 0.0024
Leishmania major hypothetical protein, conserved 0.0027 0.0178 0.0853
Brugia malayi CHD4 protein 0.0013 0.002 0.0082
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0086 0.0116
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0048 0.0416 0.0562
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.1433 1
Brugia malayi MH2 domain containing protein 0.0116 0.1177 0.4744
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0256 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0048 0.0416 0.1084
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.0002 0.0056
Onchocerca volvulus 0.0019 0.0086 0.0302
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Schistosoma mansoni nAChR subunit 0.0019 0.0086 0.0116
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0039 0.0317 0.0826
Echinococcus granulosus 7TM GPCR rhodopsin 0.0039 0.0317 0.0428
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0086 0.0116
Loa Loa (eye worm) hypothetical protein 0.0083 0.0805 0.2098
Schistosoma mansoni opsin-like receptor 0.0039 0.0317 0.0428
Echinococcus granulosus nAChR subunit 0.0019 0.0086 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0322 0.3499 0.4728
Schistosoma mansoni serine-rich repeat protein 0.0068 0.0639 0.0863
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0048 0.0416 0.0562
Loa Loa (eye worm) hypothetical protein 0.0048 0.0416 0.1084
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0115 0.0375
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0048 0.0416 0.1675
Echinococcus granulosus g protein coupled receptor 0.0039 0.0317 0.0428
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.065 0.0878
Toxoplasma gondii aldehyde dehydrogenase 0.0195 0.2065 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0115 0.0463
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Brugia malayi follicle stimulating hormone receptor 0.0039 0.0317 0.1277
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Brugia malayi hypothetical protein 0.0013 0.0017 0.007
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0416 0.0562
Loa Loa (eye worm) hypothetical protein 0.0027 0.0178 0.0465
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0048 0.0416 0.0416
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.0017 0.0017
Schistosoma mansoni biogenic amine (5HT) receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis pikachurin 0.0025 0.0154 0.0154
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0115 0.0155
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0317 0.0428
Brugia malayi Cache domain containing protein 0.0058 0.053 0.2134
Schistosoma mansoni loxhd1 0.0022 0.0122 0.0165
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0115 0.0155
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0115 0.0115
Schistosoma mansoni ap endonuclease 0.004 0.032 0.0433
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0115 0.0155
Onchocerca volvulus 0.0019 0.0086 0.0302
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0289 0.3124 0.3124
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.013 0.034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0086 0.0116
Echinococcus granulosus RUN 0.0022 0.0122 0.0165
Echinococcus granulosus lamin 0.0084 0.0822 0.1111
Schistosoma mansoni nAChR subunit 0.0019 0.0086 0.0116
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3063 1
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.013 0.0176
Onchocerca volvulus 0.0039 0.0317 0.1116
Schistosoma mansoni slit 0.0025 0.0154 0.0208
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0154 0.0208
Toxoplasma gondii PAN domain-containing protein 0.0015 0.004 0.0195
Schistosoma mansoni hypothetical protein 0.0188 0.1991 0.2691
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0115 0.0155
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.0317 0.0317
Schistosoma mansoni hypothetical protein 0.0068 0.0639 0.0863
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.002 0.0053
Onchocerca volvulus 0.0015 0.004 0.0142
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.032 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0048 0.0416 0.0562
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0123 0.0166
Echinococcus granulosus Chromobox protein 3 0.0011 0.000000015509 0.000000020957
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0086 0.0116
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0025 0.0154 0.0208
Echinococcus multilocularis dnaJ subfamily B 0.0454 0.4982 0.4982
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0039 0.0317 0.0317
Schistosoma mansoni hypothetical protein 0.0454 0.4982 0.6733
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0122 0.0165
Brugia malayi hypothetical protein 0.0135 0.1395 0.5622
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0469 0.0634
Schistosoma mansoni hypothetical protein 0.0023 0.013 0.0176
Onchocerca volvulus 0.0264 0.2841 1
Echinococcus granulosus expressed protein 0.0037 0.0293 0.0395
Loa Loa (eye worm) RecQ helicase 0.0022 0.0123 0.0321
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0086 0.0223
Echinococcus multilocularis allatostatin A receptor 0.0039 0.0317 0.0317
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0134 0.057
Brugia malayi Intermediate filament tail domain containing protein 0.0084 0.0822 0.3313
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3063 1
Schistosoma mansoni neuropeptide receptor 0.0039 0.0317 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0044 0.0142
Loa Loa (eye worm) hypothetical protein 0.0025 0.0154 0.0401
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.013 0.013
Echinococcus granulosus voltage dependent calcium channel subunit 0.0131 0.1353 0.1828
Brugia malayi TAR-binding protein 0.0061 0.0566 0.2282
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0317 0.0317
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0256 0.0346
Toxoplasma gondii hypothetical protein 0.0015 0.004 0.0195
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0039 0.0317 0.0826
Echinococcus granulosus g protein coupled receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0034 0.0256 0.0668
Schistosoma mansoni cpg binding protein 0.0034 0.0255 0.0344
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0086 0.0223
Brugia malayi SET domain containing protein 0.0013 0.0022 0.0087
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0086 0.0223
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0016 0.0053 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0253 0.0826
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0178 0.5544
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0122 0.0122
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0122 0.0122
Loa Loa (eye worm) aminopeptidase N 0.0013 0.0017 0.0046
Brugia malayi laminin-like protein K08C7.3 precursor 0.0025 0.0154 0.0619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0317 0.0428
Loa Loa (eye worm) G-protein coupled receptor 0.0039 0.0317 0.0826
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0115 0.0155
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0039 0.0317 0.0317
Brugia malayi nuclear receptor RXR 0.0025 0.0161 0.0649
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0081 0.0265
Schistosoma mansoni nuclear receptor 0.0023 0.013 0.0176
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0086 0.0086
Echinococcus granulosus chromobox protein 1 0.0068 0.0635 0.0859
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0635 0.2075
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1177 0.3069
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Brugia malayi Protein kinase domain containing protein 0.0023 0.013 0.0525
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Brugia malayi Nuclear hormone receptor E75 0.0023 0.013 0.0526
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.013 0.0176
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Echinococcus granulosus microtubule associated protein 2 0.067 0.74 1
Schistosoma mansoni nuclear hormone receptor 0.0023 0.013 0.0176
Schistosoma mansoni hypothetical protein 0.0038 0.0308 0.0416
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0069 0.5
Brugia malayi Serotonin receptor 0.0039 0.0317 0.1277
Brugia malayi putative neuropeptide receptor 0.0039 0.0317 0.1277
Echinococcus multilocularis thyroid hormone receptor alpha 0.0322 0.3499 0.3499
Entamoeba histolytica DNA repair and recombination protein, putative 0.0034 0.0253 0.0826
Trypanosoma brucei aminopeptidase, putative 0.0013 0.0017 0.0473
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0317 0.0317
Trypanosoma brucei Aminopeptidase M1, putative 0.0013 0.0017 0.0473
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0115 0.0375
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.0017 0.0024
Brugia malayi Serotonin receptor 0.0039 0.0317 0.1277
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0115 0.0155
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0039 0.0317 0.0317
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0256 0.1241
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0308 0.0416
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0086 0.0345
Toxoplasma gondii PAN domain-containing protein 0.0015 0.004 0.0195
Brugia malayi Nuclear hormone receptor E75 0.0023 0.013 0.0526
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0022 0.0123 0.0321
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0105
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0086 0.0116
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0013 0.0017 0.0473
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.004 0.0105
Onchocerca volvulus 0.0019 0.0086 0.0302
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0416 0.1675
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0566 0.0566
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0069 0.0251
Brugia malayi larval opioid receptor 0.0039 0.0317 0.1277
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0039 0.0317 0.0826
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0081 0.0265
Entamoeba histolytica hypothetical protein 0.0021 0.0115 0.0375
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1177 0.3069
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.032 0.104
Brugia malayi G protein-coupled receptor 0.0039 0.0317 0.1277
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0115 0.0375
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0195 0.2065 1
Echinococcus granulosus lamin dm0 0.0084 0.0822 0.1111
Echinococcus multilocularis lamin 0.0084 0.0822 0.0822
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0048 0.0416 0.1084
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0086 0.0223
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Onchocerca volvulus 0.0015 0.004 0.0142
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.3063 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0416 0.1675
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0013 0.0017 0.0546
Echinococcus granulosus dro:myosuppressin receptor 0.0039 0.0317 0.0428
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0013 0.0017 0.0024
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.032 0.067
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0232 0.2482 0.6469
Schistosoma mansoni rotamase 0.0037 0.0293 0.0395
Onchocerca volvulus 0.0048 0.0416 0.1464
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Toxoplasma gondii kringle domain-containing protein 0.0023 0.013 0.0631
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0115 0.0155
Schistosoma mansoni microtubule-associated protein tau 0.067 0.74 1
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0013 0.0017 0.0017
Brugia malayi hypothetical protein 0.0038 0.0308 0.1239
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0115 0.0375
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.013 0.034
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0013 0.0017 0.0493
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0011 0.0015
Toxoplasma gondii PAN/Apple domain-containing protein 0.0015 0.004 0.0195
Echinococcus granulosus 7tm_1 domain containing protein 0.0039 0.0317 0.0428
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0565 0.0565
Echinococcus multilocularis slit 2 protein 0.0025 0.0154 0.0154
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0038 0.0308 0.1004
Schistosoma mansoni myosin xvIII 0.0039 0.0317 0.0428
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0302 0.1061
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0334 0.109
Schistosoma mansoni aminopeptidase A (M01 family) 0.0013 0.0017 0.0024
Echinococcus multilocularis neuropeptide Y receptor 0.0039 0.0317 0.0317
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.013 0.013
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0048 0.0416 0.1675
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0161 0.0218
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.013 0.0176
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3063 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0115 0.0115
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0034 0.0253 0.7889
Entamoeba histolytica hypothetical protein 0.0021 0.0115 0.0375
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0013 0.0017 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0317 0.0428
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0178 0.5534
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0334 0.109
Loa Loa (eye worm) hypothetical protein 0.0025 0.0161 0.042
Echinococcus granulosus allatostatin A receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0025 0.0154 0.0401
Onchocerca volvulus 0.0053 0.0469 0.1652
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0081 0.0265
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0274 0.2959 0.2959
Onchocerca volvulus 0.0039 0.0317 0.1116
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0115 0.0463
Loa Loa (eye worm) hypothetical protein 0.0048 0.0416 0.1084
Loa Loa (eye worm) hypothetical protein 0.0048 0.0416 0.1084
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0123 0.0402
Toxoplasma gondii microneme protein MIC4 0.0015 0.004 0.0195
Toxoplasma gondii subtilisin SUB12 0.0015 0.004 0.0195
Toxoplasma gondii microneme protein MIC17C 0.0015 0.004 0.0195
Schistosoma mansoni ap endonuclease 0.004 0.032 0.0433
Brugia malayi neuropeptide F receptor 0.0039 0.0317 0.1277
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0122 0.0165
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0081 0.0265
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0566 0.2282
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.013 0.0176
Loa Loa (eye worm) hypothetical protein 0.0039 0.0315 0.0822
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0134 0.0541
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0048 0.0416 0.0562
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0039 0.0317 0.0317
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0115 0.0115
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0123 0.3811
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Onchocerca volvulus 0.0019 0.0086 0.0302
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0086 0.0116
Brugia malayi nuclear receptor NHR-88 0.0048 0.0416 0.1675
Brugia malayi PXA domain containing protein 0.0021 0.0115 0.0463
Echinococcus granulosus biogenic amine 5HT receptor 0.0039 0.0317 0.0428
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0048 0.0416 0.1675
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0238 0.2545 0.6634
Mycobacterium ulcerans hypothetical protein 0.0023 0.0134 0.057
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0123 0.3846
Schistosoma mansoni neuropeptide f receptor 76f 0.0039 0.0317 0.0428
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.013 0.034
Loa Loa (eye worm) TYRA-2 protein 0.0039 0.0317 0.0826
Echinococcus granulosus geminin 0.0188 0.1991 0.2691
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0086 0.0223
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0002 0.0002
Brugia malayi EGF-like domain containing protein 0.0025 0.0154 0.0619
Schistosoma mansoni hypothetical protein 0.0188 0.1991 0.2691
Schistosoma mansoni DNA helicase recq5 0.0022 0.0123 0.0166
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0039 0.0317 0.0428
Onchocerca volvulus Neuropeptide F receptor homolog 0.0039 0.0317 0.1116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0317 0.0428
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0039 0.0317 0.1277
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0086 0.0116
Loa Loa (eye worm) hypothetical protein 0.0025 0.0161 0.042
Schistosoma mansoni amine GPCR 0.0039 0.0317 0.0428
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0036 0.0283 0.0924
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0115 0.0155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0048 0.0416 0.1084
Echinococcus multilocularis neuropeptide receptor 0.0039 0.0317 0.0317
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0381 0.0514
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.0317 0.0317
Brugia malayi Dopamine receptor protein 1 0.0039 0.0317 0.1277
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0039 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0046
Plasmodium falciparum cysteine repeat modular protein 1 0.0023 0.013 0.4069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Echinococcus multilocularis musashi 0.0084 0.0822 0.0822
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0086 0.0223
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.002 0.0028
Schistosoma mansoni alpha-1 adrenergic receptor 0.0039 0.0317 0.0428
Onchocerca volvulus 0.0015 0.004 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0115 0.0155
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Echinococcus multilocularis orexin receptor type 2 0.0039 0.0317 0.0317
Schistosoma mansoni aldehyde dehydrogenase 0.0195 0.2065 0.279
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.004 0.0105
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0048 0.0416 0.0562
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.004 0.0105
Leishmania major hypothetical protein, conserved 0.0023 0.013 0.062
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0086 0.0345
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Trichomonas vaginalis ap endonuclease, putative 0.004 0.032 0.1045
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0039 0.0317 0.0428
Toxoplasma gondii microneme protein MIC17A 0.0015 0.004 0.0195
Schistosoma mansoni growth hormone secretagogue receptor 0.0039 0.0317 0.0428
Schistosoma mansoni DNA helicase recq1 0.0022 0.0123 0.0166
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0115 0.03
Schistosoma mansoni adenoreceptor 0.0039 0.0317 0.0428
Brugia malayi hypothetical protein 0.0022 0.0122 0.0491
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0039 0.0317 0.0317
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0034 0.0253 0.7894
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0039 0.0317 0.0826
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0039 0.0317 0.0317
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0416 0.1675
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0317 0.0428
Echinococcus granulosus bloom syndrome protein 0.0022 0.0123 0.0166
Loa Loa (eye worm) peptidase family M1 containing protein 0.0013 0.0017 0.0046
Echinococcus multilocularis sex peptide receptor 0.0039 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Schistosoma mansoni neuropeptide F-like receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0115 0.03
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0123 0.0321
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0086 0.0116
Toxoplasma gondii exonuclease III APE 0.004 0.032 0.155
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.013 0.0526
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0105
Echinococcus granulosus tar DNA binding protein 0.0061 0.0566 0.0765
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.032 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0086 0.0116
Brugia malayi ecdysone receptor 0.0023 0.013 0.0526
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0081 0.0265
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0013 0.0017 0.0057
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.3063 1
Onchocerca volvulus 0.0015 0.004 0.0142
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0134 0.0639
Brugia malayi Pre-SET motif family protein 0.0232 0.2482 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0115 0.0115
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0013 0.0017 0.0546
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0115 0.0115
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.0317 0.0428
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0178 0.0863
Brugia malayi nuclear receptor RXR 0.0023 0.013 0.0526
Schistosoma mansoni polycystin 1-related 0.0022 0.0122 0.0165
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0039 0.0317 0.0428
Schistosoma mansoni amine GPCR 0.0039 0.0317 0.0428
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Echinococcus granulosus chromobox protein 1 0.0068 0.0635 0.0859
Onchocerca volvulus 0.0039 0.0317 0.1116
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0283 0.883
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0178 0.5569
Brugia malayi hypothetical protein 0.0025 0.0161 0.0649
Brugia malayi Peptidase family M1 containing protein 0.0013 0.0017 0.007
Echinococcus multilocularis chromobox protein 1 0.0068 0.0635 0.0635
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0023 0.013 0.4069
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0039 0.0317 0.0428
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0115 0.0463
Schistosoma mansoni amine GPCR 0.0039 0.0317 0.0428
Echinococcus granulosus leukotriene A 4 hydrolase 0.0238 0.2545 0.3439
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0105
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0086 0.0345
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.0317 0.0428
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0034 0.0253 0.7889
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0115 0.0155
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0037 0.0293 0.1179
Schistosoma mansoni coup transcription factor 0.0048 0.0416 0.0562
Echinococcus multilocularis neuropeptide receptor A26 0.0039 0.0317 0.0317
Echinococcus granulosus biogenic amine 5HT receptor 0.0039 0.0317 0.0428
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0064 0.059 0.0797
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.032 1
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0123 0.0496
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0086 0.0086
Brugia malayi hypothetical protein 0.0023 0.013 0.0526
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0013 0.0017 0.0057
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.013 0.013
Onchocerca volvulus 0.0023 0.013 0.0459
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0383 0.0998
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.032 0.154
Schistosoma mansoni lamin 0.0084 0.0822 0.1111
Onchocerca volvulus 0.0013 0.0017 0.0062
Schistosoma mansoni biogenic amine (5HT) receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0048 0.0416 0.1084
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.013 0.0526
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0256 0.0256
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0635 0.2075
Echinococcus multilocularis fmrfamide receptor 0.0039 0.0317 0.0317
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0134 0.057
Echinococcus granulosus neuropeptide receptor A26 0.0039 0.0317 0.0428
Onchocerca volvulus 0.0015 0.004 0.0142
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0123 0.0402
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0013 0.0017 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.013 0.0176
Brugia malayi Steroid receptor seven-up type 2 0.0048 0.0416 0.1675
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.1433 0.6912
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.013 0.0459
Loa Loa (eye worm) hypothetical protein 0.0058 0.053 0.1381
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.013 0.013
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.013 0.0459
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0039 0.0317 0.0317
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0034 0.0253 0.0342
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0013 0.0017 0.0493
Brugia malayi steroid hormone receptor 0.0048 0.0416 0.1675
Brugia malayi hypothetical protein 0.0022 0.0122 0.0491
Toxoplasma gondii microneme protein, putative 0.0015 0.004 0.0195
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0123 0.0123
Echinococcus multilocularis Chromobox protein 3 0.0011 0.000000015509 0.000000015509
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0115 0.0155
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0069 0.215
Entamoeba histolytica hypothetical protein 0.0038 0.0308 0.1004
Onchocerca volvulus 0.0039 0.0317 0.1116
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0086 0.0345
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0178 0.5569
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0134 0.0541
Echinococcus multilocularis tissue type plasminogen activator 0.0023 0.013 0.013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3063 1
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0383 0.1542
Echinococcus multilocularis neuropeptide s receptor 0.0039 0.0317 0.0317
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Loa Loa (eye worm) neuropeptide F receptor 0.0039 0.0317 0.0826
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0122 0.3806
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0115 0.0375
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0005
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.3063 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Loa Loa (eye worm) neuropeptide F receptor 0.0039 0.0317 0.0826
Echinococcus multilocularis FTZ F1 alpha 0.0048 0.0416 0.0416
Onchocerca volvulus Bile acid receptor homolog 0.0048 0.0416 0.1464
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0134 0.0378
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0038 0.0123
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0086 0.0223
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.013 0.0176
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0086 0.0086
Trichomonas vaginalis ap endonuclease, putative 0.004 0.032 0.1045
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0134 0.0639
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0161 0.0649
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0179
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0416 0.1675
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0235 0.0317
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0333 0.0449
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0122 0.0165
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0137 0.0357
Brugia malayi nuclear receptor NHR-88 0.0023 0.013 0.0526
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.032 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.0017 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0566 0.0765
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0034 0.0253 0.1215
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0134 0.0438
Loa Loa (eye worm) hypothetical protein 0.0041 0.0333 0.0867
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0115 0.03
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0086 0.0116
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Schistosoma mansoni neuropeptide receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0086 0.0086
Brugia malayi nuclear receptor NHR-67 0.0023 0.013 0.0526
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0034 0.0253 0.1215
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.0017 0.0017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.0317 0.0428
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0044 0.0142
Loa Loa (eye worm) TATA binding protein associated factor 0.0013 0.0017 0.0046
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0086 0.0345
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.013 0.034
Loa Loa (eye worm) hypothetical protein 0.003 0.021 0.0546
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0039 0.0317 0.0428
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0256 0.0346
Onchocerca volvulus 0.0039 0.0317 0.1116
Echinococcus granulosus dnaJ subfamily B 0.0454 0.4982 0.6733
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus multilocularis G-protein coupled receptor, putative 0.0039 0.0317 0.0317
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0416 0.0562
Trichomonas vaginalis rotamase, putative 0.0036 0.0283 0.0924
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0123 0.0123
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0081 0.0265
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0115 0.0155
Onchocerca volvulus 0.0023 0.013 0.0459
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0256 0.0346
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0086 0.0345
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0086 0.0223
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0011 0.0011
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0002 0.0021
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.0017 0.0017
Echinococcus multilocularis g-protein coupled receptor 0.0039 0.0317 0.0317
Schistosoma mansoni cell polarity protein 0.0025 0.0154 0.0208
Entamoeba histolytica hypothetical protein, conserved 0.0034 0.0253 0.0826
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0048 0.0416 0.1084
Brugia malayi Pre-SET motif family protein 0.0034 0.0256 0.1032
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0134 0.057
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0034 0.0253 0.7894
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0048 0.0416 0.0562
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0013 0.0017 0.0073
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0086 0.0116
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3063 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0084 0.0822 0.2143
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0086 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0317 0.0428
Loa Loa (eye worm) intermediate filament protein 0.0084 0.0822 0.2143
Entamoeba histolytica hypothetical protein 0.0021 0.0115 0.0375
Schistosoma mansoni hypothetical protein 0.0039 0.0317 0.0428
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.0317 0.0428
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.013 0.013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0317 0.0317
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Brugia malayi ecdysteroid receptor 0.0048 0.0416 0.1675
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0179
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0317 0.0428
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0333 0.0333
Loa Loa (eye worm) melatonin receptor type 1A 0.0039 0.0317 0.0826
Brugia malayi hypothetical protein 0.0021 0.0115 0.0463
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Entamoeba histolytica aminopeptidase, putative 0.0013 0.0017 0.0057
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.002 0.0028
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0048 0.0416 0.1464
Onchocerca volvulus 0.0022 0.0122 0.0429
Brugia malayi Peptidase family M1 containing protein 0.0013 0.0017 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0317 0.0428
Schistosoma mansoni nuclear receptor 0.0023 0.013 0.0176
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0566 0.0765
Onchocerca volvulus 0.0013 0.0017 0.0062
Loa Loa (eye worm) hypothetical protein 0.0048 0.0416 0.1084
Onchocerca volvulus 0.0084 0.0822 0.2895
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0011 0.0002 0.0012
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0122 0.0318
Brugia malayi Doublecortin family protein 0.0022 0.0122 0.0491
Toxoplasma gondii aminopeptidase N, putative 0.0013 0.0017 0.0085
Echinococcus granulosus sex peptide receptor 0.0039 0.0317 0.0428
Echinococcus granulosus tissue type plasminogen activator 0.0023 0.013 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0416 0.1675
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0013 0.0017 0.0073
Brugia malayi CXXC zinc finger family protein 0.0032 0.0234 0.0944
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0034 0.0253 0.7894
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0037 0.0293 0.0763
Schistosoma mansoni cpg binding protein 0.0032 0.0234 0.0317
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0123 0.0585
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0115 0.03
Loa Loa (eye worm) hypothetical protein 0.0022 0.0122 0.0318
Giardia lamblia Rrm3p helicase 0.0034 0.0253 0.0442
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0134 0.0541
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.013 0.0176
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0048 0.0416 0.0562
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0283 0.883
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0069 0.215
Schistosoma mansoni biogenic amine receptor 0.0039 0.0317 0.0428
Schistosoma mansoni nuclear hormone receptor 0.0023 0.013 0.0176
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0039 0.0317 0.0428
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0115 0.0155
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0123 0.0596
Echinococcus multilocularis g protein coupled receptor 0.0039 0.0317 0.0317
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0002 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0317 0.0428
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0274 0.2959 0.3998
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0115 0.0155
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0115 0.0463
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Onchocerca volvulus 0.0039 0.0317 0.1116
Loa Loa (eye worm) hypothetical protein 0.0048 0.0416 0.1084
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.032 0.0433
Echinococcus granulosus orexin receptor type 2 0.0039 0.0317 0.0428
Entamoeba histolytica hypothetical protein 0.0038 0.0308 0.1004
Schistosoma mansoni nAChR subunit 0.0019 0.0086 0.0116
Brugia malayi Cytochrome P450 family protein 0.0023 0.0137 0.0553
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Brugia malayi Cation transporter family protein 0.0019 0.0086 0.0345
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.0017 0.0024
Brugia malayi G-protein coupled receptor 0.0039 0.0317 0.1277
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0086 0.0223
Brugia malayi chromobox protein homolog 3 0.0038 0.0302 0.1215
Trypanosoma cruzi aminopeptidase, putative 0.0013 0.0017 0.0493
Brugia malayi Peptidase family M1 containing protein 0.0013 0.0017 0.007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0416 0.1675
Echinococcus granulosus peptide allatostatin:somatostatin 0.0039 0.0317 0.0428
Echinococcus multilocularis dro:myosuppressin receptor 0.0039 0.0317 0.0317
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0115 0.0155
Brugia malayi Kringle domain containing protein 0.0023 0.013 0.0525
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0086 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0317 0.0317
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0566 0.1476
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3063 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0416 0.1084
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0293 0.0956
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Schistosoma mansoni opsin-like receptor 0.0039 0.0317 0.0428
Echinococcus granulosus neuropeptides capa receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0025 0.0161 0.042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0115 0.0375
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0179
Loa Loa (eye worm) histone methyltransferase 0.0011 0 0.0001
Brugia malayi nuclear hormone receptor 0.0023 0.013 0.0526
Brugia malayi ORL1-like opioid receptor 0.0039 0.0317 0.1277
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0086 0.0345
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0015 0.004 0.0195
Loa Loa (eye worm) hypothetical protein 0.0025 0.0161 0.042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.032 1
Loa Loa (eye worm) DR-78 0.0023 0.013 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0177 0.0579
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0086 0.0086
Plasmodium vivax SET domain protein, putative 0.0034 0.0256 0.8003
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0039 0.0317 0.0428
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0123 0.0166
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus granulosus neuropeptide receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0086 0.0086
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0161 0.042
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0086 0.0345
Onchocerca volvulus 0.0019 0.0086 0.0302
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.0268 0.2884 0.9416
Schistosoma mansoni aldehyde dehydrogenase 0.0195 0.2065 0.279
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0317 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0302 0.0984
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.032 0.1478
Entamoeba histolytica hypothetical protein 0.0038 0.0308 0.1004
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0002 0.0021
Brugia malayi nuclear hormone receptor 0.0048 0.0416 0.1675
Loa Loa (eye worm) hypothetical protein 0.0021 0.0115 0.03
Loa Loa (eye worm) RNA binding protein 0.0061 0.0566 0.1476
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0115 0.0115
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0086 0.0345
Schistosoma mansoni cpg binding protein 0.0034 0.0255 0.0344
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0179
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0123 0.0496
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Onchocerca volvulus 0.0015 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0195 0.2065 0.2065
Echinococcus granulosus intermediate filament protein 0.0084 0.0822 0.1111
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0039 0.0317 0.0317
Schistosoma mansoni biogenic amine receptor 0.0039 0.0317 0.0428
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0039 0.0317 0.1277
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0317 0.0428
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0416 0.0416
Echinococcus multilocularis serotonin receptor 0.0039 0.0317 0.0317
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.013 0.013
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0023 0.0134 0.035
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Brugia malayi Cation transporter family protein 0.0019 0.0086 0.0345
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0195 0.2065 0.279
Echinococcus granulosus voltage dependent calcium channel subunit 0.0289 0.3124 0.4222
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0123 0.0402
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.0317 0.0428
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.3063 1
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0566 0.1476
Echinococcus granulosus neuropeptides capa receptor 0.0039 0.0317 0.0428
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0317 0.0428
Brugia malayi hypothetical protein 0.0025 0.0161 0.0649
Schistosoma mansoni lipoxygenase 0.0061 0.0565 0.0763
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0048 0.0416 0.0416
Echinococcus granulosus cpg binding protein 0.0034 0.0255 0.0344
Loa Loa (eye worm) steroid hormone receptor 0.0048 0.0416 0.1084
Onchocerca volvulus 0.0039 0.0317 0.1116
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0416 0.0562
Schistosoma mansoni hypothetical protein 0.0039 0.0317 0.0428
Trypanosoma cruzi aminopeptidase, putative 0.0013 0.0017 0.0493
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0123 0.3846
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0025 0.0161 0.042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0039 0.0317 0.0317
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0635 0.1656
Schistosoma mansoni chromobox protein 0.0068 0.0635 0.0859
Echinococcus granulosus tumor protein p63 0.0361 0.3932 0.5313
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0238 0.2545 0.2545
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0565 0.0763
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0039 0.0317 0.0826
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0416 0.1675
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0161 0.0218
Onchocerca volvulus 0.0023 0.013 0.0459
Schistosoma mansoni hypothetical protein 0.0039 0.0317 0.0428
Brugia malayi sulfakinin receptor protein 0.0039 0.0317 0.1277
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0115 0.03
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0039 0.0317 0.0428
Brugia malayi hypothetical protein 0.0017 0.0071 0.0286
Mycobacterium ulcerans aldehyde dehydrogenase 0.0195 0.2065 1
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0086 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0177 0.0579
Brugia malayi TATA binding protein associated factor 0.0013 0.0017 0.007
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0025 0.0154 0.0619
Loa Loa (eye worm) hypothetical protein 0.0084 0.0822 0.2143
Onchocerca volvulus Protein ultraspiracle homolog 0.0048 0.0416 0.1464
Schistosoma mansoni retinoic acid receptor RXR 0.0048 0.0416 0.0562
Toxoplasma gondii aminopeptidase N protein 0.0013 0.0017 0.0085
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0039 0.0317 0.0826
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0115 0.0115
Brugia malayi Melatonin receptor type 1A 0.0039 0.0317 0.1277
Schistosoma mansoni biogenic amine receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0015 0.004 0.0142
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0115 0.0115
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.3063 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0122 0.0318
Schistosoma mansoni hypothetical protein 0.0012 0.0011 0.0015
Toxoplasma gondii PAN domain-containing protein 0.0015 0.004 0.0195
Brugia malayi PAN domain containing protein 0.0015 0.004 0.0162
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0086 0.0116
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0223
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.032 0.0834
Loa Loa (eye worm) hypothetical protein 0.0023 0.013 0.034
Echinococcus granulosus neuropeptide s receptor 0.0039 0.0317 0.0428
Echinococcus multilocularis expressed protein 0.0415 0.4536 0.4536
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0086 0.0345
Brugia malayi hypothetical protein 0.0039 0.0317 0.1277
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.0017 0.0024
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0123 0.0402

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Antiviral activity against HCV 1b in Huh7 cell line upto 10 uM by replicon assay ChEMBL. 16824756
IC50 (binding) = 1.8 uM Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase ChEMBL. 16824756
IC50 (binding) = 1.8 uM Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase ChEMBL. 16824756

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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