Detailed information for compound 448269

Basic information

Technical information
  • TDR Targets ID: 448269
  • Name: 1-(4-heptylphenyl)-2-methylprop-2-en-1-one
  • MW: 244.372 | Formula: C17H24O
  • H donors: 0 H acceptors: 1 LogP: 6.08 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCc1ccc(cc1)C(=O)C(=C)C
  • InChi: 1S/C17H24O/c1-4-5-6-7-8-9-15-10-12-16(13-11-15)17(18)14(2)3/h10-13H,2,4-9H2,1,3H3
  • InChiKey: LFTHMBBMKKTEDY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(4-heptylphenyl)-2-methyl-prop-2-en-1-one
  • 1-(4-heptylphenyl)-2-methyl-2-propen-1-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0078 0.0685 0.1342
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0014 0.0042 0.0042
Onchocerca volvulus 0.0222 0.213 0.8069
Onchocerca volvulus Putative transporter 0.0014 0.0046 0.017
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.011 0.1188
Onchocerca volvulus 0.0014 0.0042 0.0154
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0062 0.0599
Loa Loa (eye worm) ACC-1 protein 0.0124 0.114 0.114
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0017 0.0075 0.0074
Echinococcus multilocularis glycine receptor subunit beta 0.0124 0.114 0.1464
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0046 0.0045
Echinococcus granulosus allatostatin A receptor 0.0014 0.0042 0.0108
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Brugia malayi Dopamine receptor 0.0014 0.0042 0.0041
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0114 0.3133
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.034 0.0876
Schistosoma mansoni acetylcholine receptor subunit beta 0.0057 0.0473 0.1219
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0017 0.0075 0.0074
Schistosoma mansoni hypothetical protein 0.0016 0.0061 0.0155
Brugia malayi hypothetical protein 0.0057 0.0473 0.0473
Echinococcus granulosus glycine receptor subunit alpha 1 0.0124 0.114 0.2939
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0049 0.0708
Schistosoma mansoni biogenic amine receptor 0.0014 0.0042 0.0105
Trypanosoma brucei sugar transporter, putative 0.0014 0.0046 0.1239
Brugia malayi hypothetical protein 0.0119 0.1094 0.1093
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0124 0.114 0.1139
Brugia malayi neuropeptide F receptor 0.0014 0.0042 0.0041
Entamoeba histolytica hypothetical protein 0.0035 0.0253 0.4428
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0075 0.0074
Brugia malayi Serotonin receptor 0.0464 0.4547 0.4547
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0162 0.2838
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0136 0.0264
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0057 0.0473 0.0608
Brugia malayi Dopamine receptor protein 1 0.0014 0.0042 0.0041
Echinococcus multilocularis FTZ F1 alpha 0.0017 0.0075 0.0096
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.1068 1
Onchocerca volvulus 0.0078 0.0685 0.2592
Echinococcus multilocularis glycine receptor subunit beta 0.0124 0.114 0.1464
Loa Loa (eye worm) hypothetical protein 0.0028 0.0181 0.0181
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0014 0.0042 0.0041
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.011 0.3002
Onchocerca volvulus 0.0014 0.0046 0.017
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0001 0.0000047548
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus granulosus replication factor c subunit 1 0.001 0.0001 0.0003
Brugia malayi ORL1-like opioid receptor 0.0014 0.0042 0.0041
Echinococcus granulosus G protein coupled receptor 139 0.0014 0.0042 0.0108
Schistosoma mansoni neuropeptide F-like receptor 0.0014 0.0042 0.0105
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0062 0.1694
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0042 0.0105
Entamoeba histolytica hypothetical protein 0.0067 0.0569 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0075 0.0075
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Brugia malayi hypothetical protein 0.0035 0.0253 0.0252
Schistosoma mansoni biogenic amine (5HT) receptor 0.0014 0.0042 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0017 0.0075 0.0075
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0062 0.0895
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.011 0.0214
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0124 0.114 0.1464
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0506 0.1302
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0228 0.0445
Brugia malayi hypothetical protein 0.0014 0.0046 0.0045
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.114 0.1139
Echinococcus multilocularis fmrfamide receptor 0.0014 0.0042 0.0054
Echinococcus granulosus solute carrier family 22 0.0014 0.0046 0.0118
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0171 0.1595
Brugia malayi Integrin alpha pat-2 precursor 0.0053 0.0436 0.0435
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.1312 0.1311
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0199 0.0511
Brugia malayi major facilitator superfamily protein 0.0014 0.0046 0.0045
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0046 0.0655
Brugia malayi excitatory GABA receptor EXP-1A 0.0124 0.114 0.1139
Brugia malayi nuclear receptor NHR-88 0.0017 0.0075 0.0074
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0363 0.0363
Brugia malayi hypothetical protein 0.0019 0.0095 0.0094
Trichomonas vaginalis abcb9, putative 0.0021 0.011 0.0214
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0114 0.0295
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0114 0.1234
Onchocerca volvulus 0.0014 0.0042 0.0154
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0095 0.102
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0162 0.2109
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0075 0.0193
Echinococcus multilocularis integrin alpha ps 0.0053 0.0436 0.056
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0317 0.3446
Onchocerca volvulus 0.0028 0.0182 0.0686
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.1272 0.328
Schistosoma mansoni hypothetical protein 0.0101 0.0919 0.2367
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0171 0.1855
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0253 0.0651
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0043 0.0042
Echinococcus granulosus nAChR subunit 0.0124 0.114 0.2939
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.011 0.0141
Onchocerca volvulus Bile acid receptor homolog 0.0017 0.0075 0.028
Entamoeba histolytica P-glycoprotein-2 0.0021 0.011 0.1918
Schistosoma mansoni hypothetical protein 0.0035 0.0253 0.0649
Echinococcus granulosus neuropeptide Y receptor 0.0014 0.0042 0.0108
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0046 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0017 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Leishmania major protein kinase, putative 0.0078 0.0685 1
Brugia malayi Cation transporter family protein 0.0124 0.114 0.1139
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0136 0.197
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0046 0.0045
Brugia malayi hypothetical protein 0.0273 0.264 0.2639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0164 0.032
Brugia malayi Pre-SET motif family protein 0.003 0.0199 0.0198
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Brugia malayi larval opioid receptor 0.0014 0.0042 0.0041
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0013 0.0017
Schistosoma mansoni steroid hormone receptor ad4bp 0.0017 0.0075 0.0191
Loa Loa (eye worm) hypothetical protein 0.0017 0.0075 0.0075
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0062 0.09
Onchocerca volvulus 0.0124 0.114 0.4315
Brugia malayi Protein kinase domain containing protein 0.0014 0.0043 0.0042
Echinococcus multilocularis aryl hydrocarbon receptor 0.0078 0.0685 0.088
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0062 0.0667
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Brugia malayi Importin beta-1 subunit 0.0029 0.019 0.0189
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.114 0.1139
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0023 0.0315
Loa Loa (eye worm) steroid hormone receptor 0.0017 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0078 0.0682 0.0682
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0014 0.0042 0.0154
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0042 0.0108
Schistosoma mansoni survival motor neuron protein 0.0047 0.0372 0.0956
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0049 0.0095
Loa Loa (eye worm) GABA receptor subunit 0.0067 0.0569 0.0569
Giardia lamblia GTOR 0.0044 0.034 1
Schistosoma mansoni nAChR subunit 0.0124 0.114 0.2937
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0014 0.0047 0.0091
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0043 0.0043
Schistosoma mansoni amine GPCR 0.0014 0.0042 0.0105
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.0919 0.2369
Onchocerca volvulus 0.0014 0.0042 0.0154
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0044 0.0111
Onchocerca volvulus 0.0026 0.0165 0.0622
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0685 1
Trypanosoma brucei glucose transporter, putative 0.0031 0.0218 0.6002
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0014 0.0042 0.0054
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.011 0.011
Trypanosoma brucei glucose transporter, putative 0.0031 0.0218 0.6002
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0569 0.0568
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0014 0.0042 0.0054
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Schistosoma mansoni importin beta-1 0.0029 0.019 0.0488
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0057 0.0473 0.0473
Plasmodium falciparum flap endonuclease 1 0.0026 0.0162 0.1757
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0049 0.0095
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0317 0.0621
Schistosoma mansoni coup transcription factor 0.0017 0.0075 0.0191
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.0919 0.118
Brugia malayi hypothetical protein 0.0014 0.0046 0.0045
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0095 0.0122
Leishmania major protein kinase, putative 0.0078 0.0685 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0042 0.0054
Schistosoma mansoni rab6-interacting 0.0019 0.0095 0.0241
Schistosoma mansoni retinoic acid receptor RXR 0.0017 0.0075 0.0191
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0078 0.0685 1
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0062 0.0667
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0124 0.114 0.2939
Loa Loa (eye worm) hypothetical protein 0.005 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Schistosoma mansoni sugar transporter 0.0014 0.0046 0.0116
Echinococcus granulosus solute carrier family 22 0.0014 0.0046 0.0118
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0078 0.0685 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0062 0.0895
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0138 0.027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Schistosoma mansoni opsin-like receptor 0.0014 0.0042 0.0105
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Schistosoma mansoni neuropeptide f receptor 76f 0.0014 0.0042 0.0105
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0218 0.6002
Echinococcus granulosus neuropeptides capa receptor 0.0014 0.0042 0.0108
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.011 0.1188
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0682 0.7416
Schistosoma mansoni lipoxygenase 0.0114 0.1049 0.2704
Schistosoma mansoni hypothetical protein 0.0397 0.3879 1
Brugia malayi follicle stimulating hormone receptor 0.0014 0.0042 0.0041
Brugia malayi photoreceptor-specific nuclear receptor 0.0017 0.0075 0.0074
Toxoplasma gondii hypothetical protein 0.0027 0.0171 0.1855
Trypanosoma brucei glucose transporter 2A 0.0031 0.0218 0.6002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0358 0.046
Schistosoma mansoni sugar transporter 0.0014 0.0046 0.0116
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0042 0.0105
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0317 0.0621
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.011 0.0284
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.011
Echinococcus multilocularis sex peptide receptor 0.0014 0.0042 0.0054
Echinococcus multilocularis G-protein coupled receptor, putative 0.0014 0.0042 0.0054
Brugia malayi Sugar transporter family protein 0.0101 0.0919 0.0918
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0136 0.0264
Echinococcus granulosus g protein coupled receptor 0.0014 0.0042 0.0108
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0001 0.0001
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0951 0.8856
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0218 0.0426
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0062 0.0667
Schistosoma mansoni smdr2 0.0021 0.011 0.0281
Loa Loa (eye worm) hypothetical protein 0.0067 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus granulosus ecdysone induced protein 78C 0.0017 0.0075 0.0193
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0895
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0095 0.0244
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0218 0.6002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Toxoplasma gondii sugar transporter ST2 0.0014 0.0046 0.0488
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus granulosus lamin dm0 0.0026 0.0165 0.0426
Brugia malayi Doublecortin family protein 0.0019 0.0095 0.0094
Echinococcus granulosus glycine receptor subunit beta 0.0124 0.114 0.2939
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0599
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Schistosoma mansoni myosin xvIII 0.0014 0.0042 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0161 0.0315
Onchocerca volvulus Putative nachr subunit 0.0124 0.114 0.4315
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0042 0.0054
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0228 0.0445
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0001 0.00000053022
Brugia malayi G-protein coupled receptor 0.0014 0.0042 0.0041
Onchocerca volvulus 0.0014 0.0042 0.0154
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0046 0.0046
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0124 0.114 0.114
Echinococcus multilocularis musashi 0.0026 0.0165 0.0212
Schistosoma mansoni flap endonuclease-1 0.0023 0.0137 0.0352
Echinococcus granulosus g protein coupled receptor 0.0014 0.0042 0.0108
Trichomonas vaginalis ran, putative 0.0021 0.0114 0.0222
Loa Loa (eye worm) hypothetical protein 0.0067 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Brugia malayi hypothetical protein 0.0019 0.0095 0.0094
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0951 0.8856
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0124 0.114 0.2939
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0228 0.0445
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0951 0.8904
Onchocerca volvulus 0.0014 0.0042 0.0154
Schistosoma mansoni hypothetical protein 0.0014 0.0042 0.0105
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0162 0.0162
Leishmania major hypothetical protein, conserved 0.0024 0.0148 0.1893
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0124 0.114 0.1139
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Onchocerca volvulus 0.003 0.0199 0.0751
Loa Loa (eye worm) hypothetical protein 0.0028 0.0181 0.0181
Echinococcus granulosus neuropeptides capa receptor 0.0014 0.0042 0.0108
Schistosoma mansoni hypothetical protein 0.0016 0.0061 0.0155
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.011 0.0141
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.011 0.0214
Onchocerca volvulus 0.0014 0.0046 0.017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus granulosus aryl hydrocarbon receptor 0.0078 0.0685 0.1766
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0029 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0049 0.0095
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0042 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0042 0.0105
Brugia malayi hypothetical protein 0.0057 0.0473 0.0473
Schistosoma mansoni integrin alpha-ps 0.0053 0.0436 0.1122
Loa Loa (eye worm) hypothetical protein 0.0029 0.019 0.019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0358 0.0922
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0062 0.0895
Schistosoma mansoni aryl hydrocarbon receptor 0.0301 0.2913 0.7509
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0095 0.0244
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Schistosoma mansoni histamine h1 receptor 0.0014 0.0042 0.0105
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0473 0.0473
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Brugia malayi Tachykinin-like peptides receptor 99D 0.0014 0.0042 0.0041
Schistosoma mansoni growth hormone secretagogue receptor 0.0014 0.0042 0.0105
Onchocerca volvulus 0.0067 0.0569 0.2153
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0017 0.0075 0.0075
Onchocerca volvulus 0.0014 0.0042 0.0154
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0017 0.0075 0.0075
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0014 0.0042 0.0108
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.011 0.0214
Brugia malayi hypothetical protein 0.0057 0.0473 0.0473
Schistosoma mansoni loxhd1 0.0019 0.0095 0.0241
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0017 0.0075 0.0193
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.011 0.0284
Schistosoma mansoni nAChR subunit 0.0124 0.114 0.2937
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Schistosoma mansoni nAChR subunit 0.0124 0.114 0.2937
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0014 0.0042 0.0041
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Echinococcus multilocularis integrin alpha 3 0.0026 0.0158 0.0204
Onchocerca volvulus 0.0026 0.0165 0.0622
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0682 0.3196
Toxoplasma gondii sugar transporter ST1 0.0014 0.0046 0.0488
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0951 0.8856
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0095
Onchocerca volvulus 0.0124 0.114 0.4315
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Loa Loa (eye worm) hypothetical protein 0.0067 0.0569 0.0569
Brugia malayi hypothetical protein 0.0014 0.0046 0.0045
Leishmania major importin beta-1 subunit, putative 0.0023 0.0136 0.1709
Schistosoma mansoni alpha-1 adrenergic receptor 0.0014 0.0042 0.0105
Schistosoma mansoni ran 0.0021 0.0114 0.0292
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0199 0.0514
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0262 0.0513
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0413 0.3594
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0262 0.0513
Entamoeba histolytica hypothetical protein 0.0023 0.0136 0.2372
Echinococcus granulosus 7TM GPCR rhodopsin 0.0014 0.0042 0.0108
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus granulosus biogenic amine 5HT receptor 0.0014 0.0042 0.0108
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0218 0.295
Giardia lamblia Sugar-proton symporter 0.0014 0.0046 0.1322
Echinococcus granulosus 7tm_1 domain containing protein 0.0014 0.0042 0.0108
Trypanosoma brucei cytochrome P450, putative 0.0012 0.0023 0.0595
Echinococcus granulosus glycine receptor subunit beta 0.0124 0.114 0.2939
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0017 0.0075 0.0096
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0046 0.0118
Loa Loa (eye worm) sugar transporter 0.0101 0.0919 0.0919
Echinococcus multilocularis fmrfamide receptor 0.0014 0.0042 0.0054
Brugia malayi glutathione reductase 0.0046 0.0363 0.0362
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.011 0.0284
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0047 0.0122
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0363 0.394
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0042 0.0054
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0182 0.0182
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0042 0.0108
Brugia malayi hypothetical protein 0.0016 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Schistosoma mansoni nAChR subunit 0.0057 0.0473 0.1219
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0218 0.0426
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0014 0.0042 0.0105
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.011 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.025 0.0489
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0046 0.1239
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0358 0.0922
Echinococcus granulosus Ankyrin 0.0014 0.0044 0.0113
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0124 0.114 0.1464
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0682 0.6377
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0017 0.0075 0.0075
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.011 0.0214
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0251 0.3444
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Echinococcus multilocularis Ankyrin 0.0014 0.0044 0.0056
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Onchocerca volvulus Protein ultraspiracle homolog 0.0017 0.0075 0.028
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0124 0.114 0.1139
Echinococcus multilocularis integrin alpha ps 0.0026 0.0158 0.0204
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Trichomonas vaginalis abcb9, putative 0.0021 0.011 0.0214
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.034 0.034
Onchocerca volvulus 0.0014 0.0042 0.0154
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0017 0.0075 0.0096
Schistosoma mansoni hypothetical protein 0.0019 0.0095 0.0241
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0124 0.114 0.1464
Brugia malayi G protein-coupled receptor 0.0014 0.0042 0.0041
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0199 0.216
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0262 0.0674
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0199 0.0511
Toxoplasma gondii thioredoxin reductase 0.0046 0.0363 0.394
Entamoeba histolytica hypothetical protein 0.0035 0.0253 0.4428
Schistosoma mansoni hypothetical protein 0.005 0.0406 0.1044
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.011 0.0284
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Plasmodium falciparum thioredoxin reductase 0.0046 0.0363 0.394
Onchocerca volvulus 0.0047 0.0372 0.1405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0049 0.0095
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0682 0.9949
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.034 0.0665
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0067 0.0569 0.1466
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.011 0.0214
Onchocerca volvulus 0.0014 0.0046 0.017
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0199 0.0256
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0124 0.114 0.1464
Echinococcus granulosus orexin receptor type 2 0.0014 0.0042 0.0108
Onchocerca volvulus 0.0057 0.0473 0.179
Echinococcus granulosus nibrin 0.001 0.0001 0.0003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0014 0.0042 0.0108
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Trichomonas vaginalis set domain proteins, putative 0.0231 0.2211 0.4337
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0124 0.114 0.114
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0403 0.0403
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0017 0.0075 0.0191
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Leishmania major glucose transporter, lmgt1 0.0031 0.0218 0.295
Loa Loa (eye worm) hypothetical protein 0.0017 0.0075 0.0075
Loa Loa (eye worm) neuropeptide F receptor 0.0014 0.0042 0.0042
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.034 0.4788
Echinococcus multilocularis integrin alpha ps 0.0053 0.0436 0.056
Plasmodium falciparum glutathione reductase 0.0016 0.0062 0.0667
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0023 0.0023
Brugia malayi ABC transporter family protein 0.0021 0.011 0.0109
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0363 0.3098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0358 0.0924
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.025 0.0489
Echinococcus multilocularis RUN 0.0019 0.0095 0.0122
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Schistosoma mansoni amine GPCR 0.0014 0.0042 0.0105
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.114 0.1139
Trichomonas vaginalis ABC transporter, putative 0.0021 0.011 0.0214
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0262 0.0674
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0114 0.1234
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0043 0.0043
Plasmodium vivax sugar transporter, putative 0.0014 0.0046 0.0488
Brugia malayi neuropeptide F receptor 0.0014 0.0042 0.0041
Echinococcus multilocularis neuropeptide FF receptor 2 0.0014 0.0042 0.0054
Schistosoma mansoni hypothetical protein 0.0016 0.0061 0.0155
Schistosoma mansoni hypothetical protein 0.0333 0.3237 0.8346
Trypanosoma brucei glucose transporter, putative 0.0031 0.0218 0.6002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0095 0.0122
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0062 0.0667
Loa Loa (eye worm) melatonin receptor type 1A 0.0014 0.0042 0.0042
Brugia malayi hypothetical protein 0.0057 0.0473 0.0473
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0014 0.0042 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0042 0.0105
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) G-protein coupled receptor 0.0014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0067 0.0569 0.0569
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0062 0.1808
Onchocerca volvulus 0.0014 0.0042 0.0154
Echinococcus granulosus integrin alpha ps 0.0026 0.0158 0.0409
Onchocerca volvulus 0.0014 0.0042 0.0154
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0067 0.0569 0.0568
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0199 0.0256
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0114 0.3344
Echinococcus multilocularis neuropeptide Y receptor 0.0014 0.0042 0.0054
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0014 0.0042 0.0105
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0682 0.0876
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.011 0.0141
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0251 0.3651
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.019 0.5229
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.034 0.937
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0014 0.0042 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0228 0.0445
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0061 0.006
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0046 0.0488
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.011 0.0214
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0078 0.0685 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0014 0.0042 0.0054
Brugia malayi AKH receptor 0.0014 0.0042 0.0041
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0165 0.0164
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0477 0.5187
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0124 0.114 0.2939
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0895
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Echinococcus multilocularis General substrate transporter 0.0087 0.0776 0.0997
Onchocerca volvulus Huntingtin homolog 0.0119 0.1094 0.4141
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Echinococcus multilocularis g-protein coupled receptor 0.0014 0.0042 0.0054
Schistosoma mansoni neurotransmitter gated ion channel 0.0057 0.0473 0.1219
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0057 0.0473 0.0473
Onchocerca volvulus 0.0124 0.114 0.4315
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Plasmodium falciparum hexose transporter 0.0101 0.0919 1
Schistosoma mansoni neuropeptide receptor 0.0014 0.0042 0.0105
Echinococcus granulosus FTZ F1 alpha 0.0017 0.0075 0.0193
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0043 0.0055
Onchocerca volvulus 0.0014 0.0042 0.0154
Echinococcus granulosus neuropeptide Y receptor 0.0014 0.0042 0.0108
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0228 0.2472
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0062 0.0667
Loa Loa (eye worm) hypothetical protein 0.023 0.2201 0.2201
Brugia malayi Flap endonuclease-1 0.0026 0.0162 0.0161
Echinococcus multilocularis ecdysone induced protein 78C 0.0017 0.0075 0.0096
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0262 0.0337
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0124 0.114 0.2939
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0078 0.0685 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0682 0.7416
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0283 0.2736 0.7052
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0124 0.114 0.2937
Brugia malayi Cation transporter family protein 0.0124 0.114 0.1139
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0078 0.0685 0.1342
Schistosoma mansoni hypothetical protein 0.0014 0.0042 0.0105
Schistosoma mansoni opsin-like receptor 0.0014 0.0042 0.0105
Entamoeba histolytica P-glycoprotein-2 0.0021 0.011 0.1918
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.011 0.0214
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0162 0.1757
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0042 0.0108
Brugia malayi putative neuropeptide receptor 0.0014 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus multilocularis lamin dm0 0.0026 0.0165 0.0212
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0262 0.46
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0014 0.0042 0.0105
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0062 0.008
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0043 0.0055
Echinococcus granulosus snurportin 1 0.0306 0.2968 0.7652
Echinococcus granulosus hypothetical protein 0.0014 0.0042 0.0108
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0413 0.0531
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0161 0.0315
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0014 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Onchocerca volvulus 0.0014 0.0046 0.017
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.1068 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Brugia malayi CXXC zinc finger family protein 0.0028 0.0182 0.0181
Schistosoma mansoni rab6-interacting 0.0019 0.0095 0.0241
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0218 0.3172
Echinococcus granulosus peptide allatostatin:somatostatin 0.0014 0.0042 0.0108
Onchocerca volvulus 0.0057 0.0473 0.179
Brugia malayi G-protein coupled receptor 0.0014 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.009 0.0802 0.0802
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0895
Echinococcus granulosus General substrate transporter 0.0087 0.0776 0.2001
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0078 0.0685 0.1342
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.011 0.0214
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0262 0.3821
Onchocerca volvulus 0.0124 0.114 0.4315
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.034 0.4952
Onchocerca volvulus 0.0014 0.0046 0.017
Loa Loa (eye worm) hypothetical protein 0.0067 0.0569 0.0569
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0017 0.0075 0.0191
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.011 0.0214
Echinococcus multilocularis transfer RNA-Lys 0.0222 0.213 0.2737
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0014 0.0042 0.0105
Brugia malayi Sugar transporter family protein 0.0014 0.0046 0.0045
Loa Loa (eye worm) TYRA-2 protein 0.0014 0.0042 0.0042
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0358 0.046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Brugia malayi Cation transporter family protein 0.0124 0.114 0.1139
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.011 0.132
Echinococcus granulosus neuropeptide receptor A26 0.0014 0.0042 0.0108
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0283 0.8317
Onchocerca volvulus 0.0014 0.0042 0.0154
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0228 0.0445
Echinococcus granulosus alpha 1A adrenergic receptor 0.0014 0.0042 0.0108
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus multilocularis importin subunit beta 1 0.0029 0.019 0.0244
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0075 0.0074
Echinococcus multilocularis neuropeptide Y receptor 0.0014 0.0042 0.0054
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.0919 0.118
Mycobacterium ulcerans sugar transporter 0.0014 0.0046 0.021
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Onchocerca volvulus 0.0273 0.264 1
Schistosoma mansoni glucose transport protein 0.0101 0.0919 0.2367
Echinococcus multilocularis solute carrier family 22 0.0014 0.0046 0.0059
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0685 0.1342
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0017 0.0075 0.0075
Echinococcus granulosus serotonin receptor 0.0014 0.0042 0.0108
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0199 0.0511
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.034 0.937
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0014 0.0042 0.0105
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0124 0.114 0.114
Echinococcus multilocularis dro:myosuppressin receptor 0.0014 0.0042 0.0054
Schistosoma mansoni neurotransmitter gated ion channel 0.0067 0.0569 0.1466
Schistosoma mansoni cpg binding protein 0.0029 0.0198 0.0508
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0049 0.0406
Loa Loa (eye worm) hypothetical protein 0.002 0.0108 0.0108
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Brugia malayi Thioredoxin reductase 0.0046 0.0363 0.0362
Echinococcus multilocularis neuropeptide receptor A26 0.0014 0.0042 0.0054
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0403 0.0402
Echinococcus multilocularis serotonin receptor 0.0014 0.0042 0.0054
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0046 0.021
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Brugia malayi hypoxia-induced factor 1 0.093 0.9218 0.9218
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0014 0.0042 0.0054
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0124 0.114 0.1139
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0043 0.011
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0218 0.0426
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Schistosoma mansoni acetylcholine receptor-related 0.0057 0.0473 0.1219
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.011 0.0141
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.1312 0.1685
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0043 0.0158
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0413 0.1066
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.0919 0.118
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0061 0.0079
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Echinococcus multilocularis somatostatin receptor 0.0014 0.0042 0.0054
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0228 0.0445
Echinococcus multilocularis neuropeptide receptor 0.0014 0.0042 0.0054
Brugia malayi intermediate filament protein 0.0026 0.0165 0.0164
Echinococcus granulosus solute carrier family 22 0.0014 0.0046 0.0118
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Onchocerca volvulus 0.0019 0.0095 0.0355
Echinococcus multilocularis geminin 0.0333 0.3237 0.4158
Schistosoma mansoni hypothetical protein 0.0047 0.0372 0.0956
Brugia malayi nuclear hormone receptor 0.0017 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0067 0.0569 0.0569
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0062 0.1694
Echinococcus granulosus glycine receptor subunit alpha 1 0.0124 0.114 0.2939
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0124 0.114 0.114
Loa Loa (eye worm) hypothetical protein 0.0026 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0682 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0017 0.0075 0.0096
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Loa Loa (eye worm) hypothetical protein 0.0013 0.0029 0.0029
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0061 0.0158
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0363 0.0466
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0138 0.027
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0017 0.0075 0.0074
Trypanosoma cruzi hexose transporter 0.0031 0.0218 0.3172
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.011 0.0214
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0029 0.0038
Brugia malayi bHLH-PAS transcription factor 0.0222 0.213 0.213
Onchocerca volvulus 0.0014 0.0042 0.0154
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0114 0.1656
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0951 0.8856
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.114 0.1139
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Brugia malayi hypothetical protein 0.023 0.2201 0.2201
Echinococcus granulosus GPCR family 2 0.0016 0.0061 0.0158
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.011 0.1188
Loa Loa (eye worm) hypothetical protein 0.0017 0.0075 0.0075
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0043 0.0042
Echinococcus multilocularis jun protein 0.0348 0.3389 0.4353
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0078 0.0685 0.0685
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.025 0.0489
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0062 0.1694
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0162 0.2357
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0025
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0473 0.0473
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.011 0.0214
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0218 0.3172
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Echinococcus granulosus neuropeptide receptor 0.0014 0.0042 0.0108
Schistosoma mansoni polycystin 1-related 0.0019 0.0095 0.0241
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0042 0.0105
Echinococcus multilocularis serotonin receptor 0.0014 0.0042 0.0054
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0262 0.0677
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0017 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0067 0.0569 0.0569
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.011 0.0214
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0403 0.0402
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.011 0.1918
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0148 0.1601
Brugia malayi sulfakinin receptor protein 0.0014 0.0042 0.0041
Onchocerca volvulus 0.0067 0.0569 0.2153
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.3879 0.4982
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.1068 1
Brugia malayi Steroid receptor seven-up type 2 0.0017 0.0075 0.0074
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0124 0.114 0.1464
Schistosoma mansoni neuropeptide receptor 0.0014 0.0042 0.0105
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0363 0.5285
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.034 0.5961
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0046 0.021
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0042 0.0054
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0062 0.0288
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0162 0.446
Loa Loa (eye worm) hypothetical protein 0.0026 0.016 0.016
Echinococcus multilocularis ATP binding cassette sub family B 0.002 0.0108 0.0138
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0046 0.0655
Schistosoma mansoni neurotransmitter gated ion channel 0.0057 0.0473 0.1219
Loa Loa (eye worm) hypothetical protein 0.0017 0.0075 0.0075
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0046 0.0488
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0114 0.0147
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.011 0.1593
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.034 0.0339
Echinococcus granulosus solute carrier family 22 0.0014 0.0046 0.0118
Echinococcus multilocularis snurportin 1 0.0306 0.2968 0.3812
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0049 0.0127
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0046 0.0059
Brugia malayi Cytochrome P450 family protein 0.0012 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0306 0.2968 0.2968
Plasmodium vivax glutathione reductase, putative 0.0046 0.0363 0.394
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.011 0.0141
Brugia malayi hypothetical protein 0.0024 0.0148 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0046 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0042 0.0054
Echinococcus multilocularis G protein coupled receptor 139 0.0014 0.0042 0.0054
Echinococcus granulosus cpg binding protein 0.0029 0.0198 0.0511
Echinococcus multilocularis solute carrier family 22 0.0014 0.0046 0.0059
Echinococcus multilocularis thyroid hormone receptor alpha 0.0017 0.0075 0.0096
Brugia malayi STAT protein, DNA binding domain containing protein 0.0128 0.1181 0.118
Schistosoma mansoni nAChR subunit 0.0124 0.114 0.2937
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0042 0.0054
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0078 0.0685 0.1342
Trichomonas vaginalis abcb9, putative 0.0021 0.011 0.0214
Entamoeba histolytica Ran family GTPase 0.0021 0.0114 0.1993
Loa Loa (eye worm) acetylcholine receptor protein 0.0057 0.0473 0.0473
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0124 0.114 0.2937
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0171 0.1855
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0124 0.114 0.1139
Schistosoma mansoni multidrug resistance protein 0.0021 0.011 0.0281
Schistosoma mansoni lipoxygenase 0.008 0.0704 0.1814
Echinococcus multilocularis nAChR subunit 0.0124 0.114 0.1464
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0095 0.102
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0358 0.0358
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0682 0.3196
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.011 0.0628
Echinococcus granulosus neuropeptide FF receptor 2 0.0014 0.0042 0.0108
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0014 0.0042 0.0054
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0682 0.9949
Trichomonas vaginalis ABC transporter, putative 0.0021 0.011 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0519 0.5097 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0317 0.0818
Trypanosoma brucei glucose transporter 1E 0.0031 0.0218 0.6002
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0046 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0042 0.0105
Echinococcus multilocularis nibrin 0.001 0.0001 0.0001
Echinococcus granulosus tachykinin peptides receptor 99D 0.0014 0.0042 0.0108
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0251 0.6908
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0095
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0262 0.0677
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0199 0.0511
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0124 0.114 0.114
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0057 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0062 0.016
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0682 0.1757
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.011
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0075 0.0074
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0317 0.3446
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0124 0.114 0.1139
Loa Loa (eye worm) hypothetical protein 0.0339 0.3293 0.3293
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0787 0.7785 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0049 0.0406
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0017 0.0075 0.0075
Entamoeba histolytica hypothetical protein 0.0035 0.0253 0.4428
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0014 0.0042 0.0054
Schistosoma mansoni neuropeptide F-like receptor 0.0014 0.0042 0.0105
Brugia malayi putative neuropeptide receptor NPR1 0.0014 0.0042 0.0041
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0014 0.0042 0.0054
Schistosoma mansoni biogenic amine receptor 0.0014 0.0042 0.0105
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.011 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0519 0.5097 1
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Brugia malayi hypothetical protein 0.0014 0.0042 0.0041
Brugia malayi Probable ClpP-like protease 0.0078 0.0682 0.0681
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.003 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0165 0.0165
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.034 0.0874
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0124 0.114 0.1464
Echinococcus granulosus RUN 0.0019 0.0095 0.0244
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0017 0.0075 0.0193
Onchocerca volvulus 0.0231 0.2213 0.838
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0473 0.0473
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0685 0.1342
Onchocerca volvulus 0.0057 0.0473 0.179
Trichomonas vaginalis guanylate cyclase, putative 0.0078 0.0685 0.1342
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0042 0.0108
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0682 0.1755
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0283 0.307
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.011 0.0214
Onchocerca volvulus 0.0014 0.0046 0.017
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.002 0.0108 0.0278
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0049 0.0708
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0017 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0101 0.0919 0.118
Schistosoma mansoni integrin alpha-ps 0.0028 0.0181 0.0463
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0253 0.0325
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0599
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0218 0.0426
Echinococcus multilocularis multidrug resistance protein 1 0.0014 0.0047 0.0061
Schistosoma mansoni sugar transporter 0.0014 0.0046 0.0116
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0062 0.0288
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0017 0.0075 0.0096
Echinococcus granulosus glycine receptor subunit alpha 1 0.0124 0.114 0.2939
Schistosoma mansoni RAR-like nuclear receptor 0.0017 0.0075 0.0191
Schistosoma mansoni integrin alpha 0.0053 0.0436 0.1122
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0047 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0046 0.0088
Schistosoma mansoni nAChR subunit 0.0057 0.0473 0.1219
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0046 0.0045
Schistosoma mansoni adenoreceptor 0.0014 0.0042 0.0105
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0062 0.012
Loa Loa (eye worm) hypoxia-induced factor 1 0.093 0.9218 0.9218
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0895
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0062 0.0161
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.0919 0.2369
Loa Loa (eye worm) hypothetical protein 0.0036 0.0262 0.0262
Brugia malayi Cytochrome P450 family protein 0.0012 0.0023 0.0022
Toxoplasma gondii sugar transporter ST3 0.0014 0.0046 0.0488
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Onchocerca volvulus 0.0014 0.0042 0.0154
Echinococcus multilocularis cpg binding protein 0.0029 0.0198 0.0254
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0162 0.0316
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0245 0.0244
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0067 0.0569 0.1466
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0218 0.3172
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0262 0.3821
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.011 0.0214
Echinococcus granulosus biogenic amine 5HT receptor 0.0014 0.0042 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0075 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.0919 0.1801
Schistosoma mansoni sugar transporter 0.0014 0.0046 0.0116
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0046 0.021
Schistosoma mansoni neuropeptide receptor 0.0014 0.0042 0.0105
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0017 0.0075 0.0075
Schistosoma mansoni nAChR subunit 0.0124 0.114 0.2937
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0075 0.0096
Loa Loa (eye worm) hypothetical protein 0.0017 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0017 0.0075 0.0191
Onchocerca volvulus 0.0014 0.0046 0.017
Echinococcus multilocularis allatostatin A receptor 0.0014 0.0042 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.025 0.0489
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0075 0.0096
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.0919 0.2369
Brugia malayi Death domain containing protein 0.0014 0.0043 0.0042
Schistosoma mansoni nAChR subunit 0.0124 0.114 0.2937
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0042 0.0105
Schistosoma mansoni biogenic amine (5HT) receptor 0.0014 0.0042 0.0105
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0061 0.0158
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.1049 0.1348
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0014 0.0042 0.0105
Brugia malayi RE15519p 0.0014 0.0042 0.0041
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0348 0.3389 0.4353
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0014 0.0042 0.0105
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0014 0.0042 0.0042
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0049 0.0049
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0114 0.0113
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0043 0.011
Plasmodium vivax hexose transporter 0.0101 0.0919 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0124 0.114 0.1139
Echinococcus granulosus neuropeptide s receptor 0.0014 0.0042 0.0108
Brugia malayi ecdysteroid receptor 0.0017 0.0075 0.0074
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0682 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0012 0.0023 0.0101
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0124 0.114 0.2939
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0148 0.1601
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.002 0.0019
Echinococcus granulosus single minded 2 0.0222 0.213 0.5493
Schistosoma mansoni hypothetical protein 0.0011 0.0013 0.0031
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.011 0.1918
Schistosoma mansoni multidrug resistance protein 0.0021 0.011 0.0281
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.1312 0.338
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0043 0.0108
Entamoeba histolytica hypothetical protein 0.0035 0.0253 0.4428
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0057 0.0473 0.1221
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0042 0.0108
Leishmania major trypanothione reductase 0.0046 0.0363 0.5132
Schistosoma mansoni amine GPCR 0.0014 0.0042 0.0105
Echinococcus granulosus survival motor neuron protein 1 0.023 0.2201 0.5676
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0046 0.0088
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0042 0.0054
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0078 0.0685 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0014 0.0042 0.0054
Leishmania major p-glycoprotein 0.0021 0.011 0.132
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0014 0.0042 0.0042
Plasmodium vivax SET domain protein, putative 0.003 0.0199 0.216
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0017 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0078 0.0685 0.0685
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0218 0.6002
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0061 0.006
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.2201 0.2828
Schistosoma mansoni amine GPCR 0.0014 0.0042 0.0105
Mycobacterium ulcerans putative regulatory protein 0.0222 0.213 1
Loa Loa (eye worm) STAT protein 0.0128 0.1181 0.1181
Leishmania major glucose transporter, lmgt3 0.0031 0.0218 0.295
Schistosoma mansoni hypothetical protein 0.0014 0.0043 0.0108
Schistosoma mansoni glucose transport protein 0.0101 0.0919 0.2367
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0682 0.7416
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0165 0.0165
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0253 0.0649
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0619 0.1595
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0042 0.0054
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0057 0.0473 0.0608
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0685 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.011 0.0141
Echinococcus granulosus dnaJ subfamily B 0.0397 0.3879 1
Echinococcus multilocularis GPCR, family 2 0.0016 0.0061 0.0079
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0095 0.0244
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0148 0.2148
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0124 0.114 0.1464
Echinococcus granulosus g protein coupled receptor 0.0014 0.0042 0.0108
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0049 0.0048
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0014 0.0042 0.0042
Entamoeba histolytica P-glycoprotein-1 0.0021 0.011 0.1918
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0218 0.0426
Onchocerca volvulus 0.0021 0.011 0.0413
Onchocerca volvulus 0.0014 0.0042 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0042 0.0054
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0951 0.8856
Onchocerca volvulus 0.0014 0.0046 0.017
Onchocerca volvulus 0.0014 0.0046 0.017
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.011 0.0214
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0358 0.0357
Schistosoma mansoni cpg binding protein 0.0028 0.0182 0.0467
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Echinococcus granulosus sex peptide receptor 0.0014 0.0042 0.0108
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0046 0.0088
Trypanosoma brucei glucose transporter, putative 0.0031 0.0218 0.6002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0276 0.0539
Schistosoma mansoni hypothetical protein 0.0016 0.0061 0.0155
Echinococcus granulosus fmrfamide receptor 0.0014 0.0042 0.0108
Brugia malayi Sugar transporter family protein 0.0014 0.0046 0.0045
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0124 0.114 0.2939
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.002 0.0019
Schistosoma mansoni amine GPCR 0.0175 0.1652 0.4257
Schistosoma mansoni glucose transport protein 0.0101 0.0919 0.2367
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0358 0.0924
Echinococcus granulosus g-protein coupled receptor 0.0014 0.0042 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0042 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0042 0.0108
Echinococcus multilocularis solute carrier family 22 0.0014 0.0046 0.0059
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0182 0.047
Onchocerca volvulus 0.0124 0.114 0.4315
Onchocerca volvulus 0.0124 0.114 0.4315
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0078 0.0685 0.088
Schistosoma mansoni hypothetical protein 0.0014 0.0042 0.0105
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0049 0.134
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0057 0.0473 0.0473
Schistosoma mansoni opsin-like receptor 0.0014 0.0042 0.0105
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0262 0.0337
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0046 0.0088
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0317 0.3446
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0262 0.7716
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0049 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0042 0.0054
Brugia malayi GnHR receptor homolog 0.0014 0.0042 0.0041
Plasmodium falciparum glutathione reductase 0.0046 0.0363 0.394
Echinococcus multilocularis neuropeptide s receptor 0.0014 0.0042 0.0054
Trichomonas vaginalis adenylate cyclase, putative 0.0078 0.0685 0.1342
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0124 0.114 0.2937
Mycobacterium leprae Possible regulatory protein 0.0078 0.0685 0.641
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Onchocerca volvulus 0.0014 0.0042 0.0154
Trypanosoma brucei trypanothione reductase 0.0046 0.0363 1
Echinococcus multilocularis orexin receptor type 2 0.0014 0.0042 0.0054
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0046 0.0046
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.114 0.1139
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0062 0.1694
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Schistosoma mansoni jun-related protein 0.0283 0.2736 0.7052
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0078 0.0685 1
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0162 0.0208
Echinococcus granulosus lamin 0.0026 0.0165 0.0426
Onchocerca volvulus 0.0014 0.0046 0.017
Echinococcus granulosus somatostatin receptor 0.0014 0.0042 0.0108
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0162 0.1757
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0014 0.0042 0.0054
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0042 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.034 0.0665
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.011 0.1188
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0042 0.0054
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0062 0.0895
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0014 0.0042 0.0105
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0061 0.0079
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0124 0.114 0.2939
Treponema pallidum NADH oxidase 0.0016 0.0062 0.09
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.025 0.0489
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.034 0.4788
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0171 0.2501
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0619 0.0795
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0124 0.114 0.2937
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.114 0.1139
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0062 0.0288
Loa Loa (eye worm) neuropeptide F receptor 0.0014 0.0042 0.0042
Loa Loa (eye worm) sugar transporter 0.0014 0.0046 0.0046
Echinococcus multilocularis solute carrier family 22 0.0014 0.0046 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0196 0.0383
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0138 0.027
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0057 0.0473 0.1221
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0095 0.0122
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0014 0.0042 0.0041
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0569 0.0568
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0017 0.0075 0.0191
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0363 0.0935
Loa Loa (eye worm) LGC-31 protein 0.0124 0.114 0.114
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.011 0.0284
Trypanosoma brucei glucose transporter, putative 0.0031 0.0218 0.6002
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.1068 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0042 0.0054
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0014 0.0042 0.0108
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0075 0.0191
Loa Loa (eye worm) G-protein coupled receptor 0.0014 0.0042 0.0042
Leishmania major hypothetical protein, conserved 0.0014 0.0046 0.0351
Schistosoma mansoni hypothetical protein 0.0306 0.2968 0.7651
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.011 0.0214
Schistosoma mansoni ran 0.0021 0.0114 0.0292
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.002 0.0038
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0124 0.114 0.1464
Trichomonas vaginalis ABC transporter, putative 0.0021 0.011 0.0214
Giardia lamblia Hexose transporter 0.0014 0.0046 0.1322
Trypanosoma brucei glucose transporter, putative 0.0031 0.0218 0.6002
Brugia malayi hypothetical protein 0.0057 0.0473 0.0473
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0046 0.0116
Trichomonas vaginalis ABC transporter, putative 0.0021 0.011 0.0214
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0124 0.114 0.2937
Echinococcus granulosus importin subunit beta 1 0.0029 0.019 0.049
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0046 0.0351
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.011 0.0214
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0067 0.0569 0.0568
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0075 0.0191
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0262 0.0513
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0187 0.0364
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0685 0.1342
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.011 0.0214
Onchocerca volvulus 0.0014 0.0042 0.0154
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0042 0.0108
Schistosoma mansoni single-minded 0.0301 0.2913 0.7509
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0042 0.0108
Loa Loa (eye worm) hypothetical protein 0.0067 0.0569 0.0569
Loa Loa (eye worm) glutathione reductase 0.0046 0.0363 0.0363
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0124 0.114 0.1139
Onchocerca volvulus 0.0014 0.0046 0.017
Schistosoma mansoni lamin 0.0026 0.0165 0.0423
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0228 0.0445
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0049 0.134
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0148 0.4065
Schistosoma mansoni multidrug resistance protein 0.0021 0.011 0.0281
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.034 0.5961
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0895
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.011 0.0214
Echinococcus granulosus integrin alpha ps 0.0053 0.0436 0.1124
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.011 0.1918
Onchocerca volvulus 0.0017 0.0075 0.028
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0001 0.00000069684
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0372 0.0371
Echinococcus multilocularis nAChR subunit 0.0067 0.0569 0.0731
Loa Loa (eye worm) hypothetical protein 0.0034 0.0245 0.0245
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0413 0.3594
Brugia malayi Dopamine receptor protein 2 0.0014 0.0042 0.0041
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0001 0.0000029442
Echinococcus granulosus intermediate filament protein 0.0026 0.0165 0.0426
Loa Loa (eye worm) acetyltransferase 0.0141 0.1312 0.1312
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0124 0.114 0.1139
Plasmodium falciparum importin beta, putative 0.0029 0.019 0.206
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.011 0.0141
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0078 0.0685 0.1766
Trypanosoma brucei glucose transporter, putative 0.0031 0.0218 0.6002
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.011 0.0284
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0014 0.0042 0.0108
Onchocerca volvulus 0.0014 0.0042 0.0154
Schistosoma mansoni biogenic amine receptor 0.0014 0.0042 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0042 0.0105
Loa Loa (eye worm) hypothetical protein 0.0026 0.0165 0.0165
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0124 0.114 0.2939
Loa Loa (eye worm) hypothetical protein 0.0119 0.1094 0.1094
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0057 0.0473 0.0608
Echinococcus granulosus geminin 0.0333 0.3237 0.8346
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0014 0.0042 0.0054
Trichomonas vaginalis taga, putative 0.0021 0.011 0.0214
Schistosoma mansoni intermediate filament proteins 0.0026 0.0165 0.0423
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0895
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0114 0.1234
Brugia malayi Melatonin receptor type 1A 0.0014 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0062 0.09
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0062 0.0061
Loa Loa (eye worm) integrin alpha pat-2 0.0118 0.108 0.108
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0148 0.1601
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0124 0.114 0.1464
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0046 0.0118
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0001 0.00000053022
Onchocerca volvulus Neuropeptide F receptor homolog 0.0014 0.0042 0.0154
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0124 0.114 0.1139
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0124 0.114 0.2937
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0014 0.0042 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0042 0.0054
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0162 0.476
Brugia malayi steroid hormone receptor 0.0017 0.0075 0.0074
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0017 0.0075 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Leishmania major GTP-binding protein, putative 0.0021 0.0114 0.1385
Onchocerca volvulus 0.0014 0.0046 0.017
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.1049 0.2705
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0017 0.0075 0.028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0042 0.0105
Schistosoma mansoni neuropeptide receptor 0.0014 0.0042 0.0105
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0348 0.3389 0.8737
Echinococcus granulosus flap endonuclease 1 0.0026 0.0162 0.0418
Mycobacterium tuberculosis Probable reductase 0.0105 0.0951 0.8856
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0262 0.0677
Onchocerca volvulus 0.0014 0.0046 0.017
Echinococcus multilocularis neuropeptides capa receptor 0.0014 0.0042 0.0054
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0062 0.0158
Schistosoma mansoni hypothetical protein 0.0333 0.3237 0.8346
Echinococcus granulosus jun protein 0.0348 0.3389 0.8737
Brugia malayi PAS domain containing protein 0.0301 0.2913 0.2912
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Brugia malayi Serotonin receptor 0.0014 0.0042 0.0041
Entamoeba histolytica P-glycoprotein-5 0.0021 0.011 0.1918
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0262 0.723
Plasmodium vivax importin-beta 2, putative 0.0029 0.019 0.206
Brugia malayi Pre-SET motif family protein 0.0203 0.1932 0.1931
Schistosoma mansoni hypothetical protein 0.0014 0.0042 0.0105
Loa Loa (eye worm) hypothetical protein 0.0067 0.0569 0.0569
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0124 0.114 0.1464
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.034 0.0436
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0014 0.0042 0.0054
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Onchocerca volvulus Huntingtin homolog 0.0119 0.1094 0.4141
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0075 0.0074
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0046 0.0059
Loa Loa (eye worm) hypothetical protein 0.0119 0.1094 0.1094
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0042 0.0108
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.034 0.4952
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Onchocerca volvulus 0.0014 0.0046 0.017
Echinococcus granulosus nAChR subunit 0.0067 0.0569 0.1468
Echinococcus multilocularis neuropeptide receptor 0.0014 0.0042 0.0054
Toxoplasma gondii facilitative glucose transporter GT1 0.0101 0.0919 1
Brugia malayi Uncoordinated protein 44 0.0014 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0046 0.0655
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0062 0.0667
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0062 0.0599
Onchocerca volvulus 0.0014 0.0046 0.017
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0262 0.0337
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0136 0.0264
Onchocerca volvulus 0.0019 0.0095 0.0355
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.019 0.5229
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) ACC-1 protein 0.0124 0.114 0.114
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0075 0.0191
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0044
Trichomonas vaginalis guanylate cyclase, putative 0.0078 0.0685 0.1342
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0075 0.0193
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0046 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0042 0.0105
Brugia malayi major facilitator superfamily protein 0.0014 0.0046 0.0045
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0283 0.4958
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0075 0.0074
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0114 0.1656
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0017 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0034 0.0245 0.0629
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0014 0.0042 0.0042
Brugia malayi Integrin alpha cytoplasmic region family protein 0.009 0.0802 0.0801
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.011 0.0284
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0682 0.7416
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0046 0.0088
Echinococcus granulosus integrin alpha 3 0.0026 0.0158 0.0409
Brugia malayi bZIP transcription factor family protein 0.0348 0.3389 0.3388
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.0919 0.2369
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0023 0.0315
Echinococcus multilocularis lamin 0.0026 0.0165 0.0212
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0049 0.0064
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0148 0.2148
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0078 0.0685 0.1342
Schistosoma mansoni glucose transporter 0.0014 0.0046 0.0116
Echinococcus multilocularis neuropeptides capa receptor 0.0014 0.0042 0.0054
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0017 0.0075 0.0074
Echinococcus granulosus death domain containing protein 0.0014 0.0043 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.027
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0017 0.0075 0.0191
Trypanosoma brucei glucose transporter, putative 0.0031 0.0218 0.6002
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0218 0.0426
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0075 0.0191
Onchocerca volvulus 0.0014 0.0046 0.017
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0062 0.012
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0057 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0014 0.0042 0.0108
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0413 0.3863
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0262 0.0261
Schistosoma mansoni lamin 0.0026 0.0165 0.0423
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0042 0.0054
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Schistosoma mansoni cpg binding protein 0.0029 0.0198 0.0508
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Schistosoma mansoni nAChR subunit 0.0124 0.114 0.2937
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0024 0.0148 0.0148
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0358 0.0922
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0084 0.2307
Echinococcus granulosus neuropeptide receptor 0.0014 0.0042 0.0108
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Loa Loa (eye worm) hypothetical protein 0.1008 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0049 0.0095
Leishmania major glucose transporter, lmgt2 0.0031 0.0218 0.295
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0124 0.114 0.114
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.011 0.0214
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Brugia malayi RNA, U transporter 1 0.0082 0.0719 0.0718
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0164 0.032
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0014 0.0042 0.0108
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0148 0.1601
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0262 0.362
Schistosoma mansoni hypothetical protein 0.0026 0.0158 0.0406
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0017 0.0075 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0164 0.032
Loa Loa (eye worm) hypothetical protein 0.0124 0.114 0.114
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0001 0.00000053022
Echinococcus granulosus dro:myosuppressin receptor 0.0014 0.0042 0.0108
Brugia malayi G protein-coupled receptor F59B2.13 0.0014 0.0042 0.0041
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.1932 0.1932
Brugia malayi multidrug resistance protein 3 0.0021 0.011 0.0109
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.019 0.206
Schistosoma mansoni netrin receptor unc5 0.0014 0.0043 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0218 0.0426
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.0046 0.0658
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.034 0.0665
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0017 0.0075 0.0193
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0075 0.1084
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Plasmodium falciparum thioredoxin reductase 0.0016 0.0062 0.0667

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 23.2 uM Displacement of labeled SRC2-2 from human TRbeta expressed in BL21 (DE3) cells FP assay ChEMBL. 17918822
IC50 (binding) = 23.2 uM Displacement of labeled SRC2-2 from human TRbeta expressed in BL21 (DE3) cells FP assay ChEMBL. 17918822
IC50 (binding) = 52.9 uM Displacement of labeled SRC2-2 from human TRalpha by FP assay ChEMBL. 17918822
IC50 (binding) = 52.9 uM Displacement of labeled SRC2-2 from human TRalpha by FP assay ChEMBL. 17918822
LD50 (functional) = 10.7 uM Cytotoxicity against human ARO cells after 48 hrs by MTS assay ChEMBL. 17918822
LD50 (functional) = 10.7 uM Cytotoxicity against human ARO cells after 48 hrs by MTS assay ChEMBL. 17918822
LD50 (functional) = 18.7 uM Cytotoxicity against human U2OS cells after 48 hrs by MTS assay ChEMBL. 17918822
LD50 (functional) = 18.7 uM Cytotoxicity against human U2OS cells after 48 hrs by MTS assay ChEMBL. 17918822
permeability (ADMET) = 43 10^-6 cm/s Permeability across artificial membrane at pH 7.4 by PAMPA assay ChEMBL. 17918822
Ratio IC50 (binding) = 2.3 Selectivity ratio of IC50 for TRBeta to IC50 for TRalpha ChEMBL. 17918822
Solubility = 37 uM Solubility in PBS ChEMBL. 17918822

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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