Detailed information for compound 505541

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1646.68 | Formula: C77H91N13O26S
  • H donors: 16 H acceptors: 23 LogP: 0.9 Rotable bonds: 45
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC(=O)CC[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCCCC1C(=O)N1C[C@H](C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCC(=O)O)CCC(=O)O)O/N=C\c1ccc(c(c1)C(=O)O)O)C)[C@H](O)C)NC(=O)[C@@H]1CCCN1C(=O)CCCCNC(=S)Nc1ccc2c(c1)C1(OC2=O)c2ccc(cc2Oc2c1ccc(c2)O)O
  • InChi: 1S/C77H91N13O26S/c1-38(71(108)89-28-6-4-9-55(89)73(110)90-37-44(116-80-36-40-13-23-57(94)46(31-40)74(111)112)35-56(90)69(106)84-51(21-25-62(98)99)66(103)83-50(65(78)102)20-24-61(96)97)81-70(107)64(39(2)91)86-68(105)54-11-8-30-88(54)72(109)52(22-26-63(100)101)85-67(104)53-10-7-29-87(53)60(95)12-3-5-27-79-76(117)82-41-14-17-45-49(32-41)77(115-75(45)113)47-18-15-42(92)33-58(47)114-59-34-43(93)16-19-48(59)77/h13-19,23,31-34,36,38-39,44,50-56,64,91-94H,3-12,20-22,24-30,35,37H2,1-2H3,(H2,78,102)(H,81,107)(H,83,103)(H,84,106)(H,85,104)(H,86,105)(H,96,97)(H,98,99)(H,100,101)(H,111,112)(H2,79,82,117)/b80-36-/t38-,39+,44-,50-,51-,52-,53-,54-,55?,56-,64-/m0/s1
  • InChiKey: LZLYQKCABTTYHA-GWORHGMCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0086 0.0255
Schistosoma mansoni tsg101-related 0.007 0.0208 0.048
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0205 0.5515
Schistosoma mansoni hypothetical protein 0.0049 0.0126 0.0291
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0037
Brugia malayi hypothetical protein 0.0038 0.0086 0.0255
Echinococcus multilocularis slit 2 protein 0.0054 0.0147 0.0141
Loa Loa (eye worm) hypothetical protein 0.0083 0.0258 0.0779
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0213
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0231
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0054 0.0147 0.0339
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0108 0.0888
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0038 0.0085 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0213
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0136 0.0314
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0039 0.0285
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0006 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0037 0.0081 0.0075
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0249
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Brugia malayi hypothetical protein 0.0017 0.0006 0.0006
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0086 0.02
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0037 0.0081 0.0237
Schistosoma mansoni slit 0.0054 0.0147 0.0339
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0231 0.0826 0.1909
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0049 0.0126 0.4788
Loa Loa (eye worm) RGS-3 protein 0.0038 0.0086 0.0249
Onchocerca volvulus 0.0038 0.0085 0.0215
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0086 0.0255
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.002 0.005
Onchocerca volvulus 0.0049 0.0126 0.0325
Brugia malayi nuclear receptor RXR 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0153 0.5966
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0038 0.0085 0.0197
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.036 1
Schistosoma mansoni hypothetical protein 0.0049 0.0126 0.029
Brugia malayi serine/threonine-protein kinase plk-2 0.009 0.0287 0.0873
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0153 0.0148
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0287 0.0756
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.036 0.0953
Mycobacterium ulcerans aldehyde dehydrogenase 0.025 0.0899 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0037 0.0081 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.003 0.0469
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0117 0.039 0.0385
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0053 0.1188
Brugia malayi regulator of G-protein signaling rgs-7 0.0038 0.0086 0.0255
Trypanosoma brucei polo-like protein kinase 0.009 0.0287 0.7727
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.025 0.0899 0.0893
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0231 0.0826 0.0821
Brugia malayi hypothetical protein 0.0038 0.0086 0.0255
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0049 0.0126 0.0321
Brugia malayi hypothetical protein 0.0019 0.0014 0.0031
Schistosoma mansoni hypothetical protein 0.0032 0.0064 0.0148
Schistosoma mansoni intermediate filament proteins 0.0083 0.0258 0.0596
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0082 0.0076
Loa Loa (eye worm) CUTiclin family member 0.0049 0.0126 0.0371
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0037 0.0081 0.0231
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0038 0.0085 0.0252
Brugia malayi hypothetical protein 0.0084 0.0262 0.0796
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0037 0.0081 0.0231
Onchocerca volvulus 0.0288 0.1046 0.2816
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Brugia malayi nuclear hormone receptor 0.0017 0.0006 0.0006
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.036 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0205 0.0199
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0086 0.0081
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0014 0.0008
Brugia malayi metabotropic glutamate receptor type 2 0.0046 0.0118 0.0352
Brugia malayi PXA domain containing protein 0.0038 0.0086 0.0255
Onchocerca volvulus 0.0024 0.003 0.0066
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0005
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0053 0.1025
Trypanosoma cruzi polo-like protein kinase, putative 0.009 0.0287 0.7893
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0037 0.0081 0.0231
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0086 0.0081
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.002 0.0018 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.036 0.0953
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0066 0.0193
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Echinococcus granulosus expressed protein 0.0033 0.0066 0.0061
Brugia malayi CXXC zinc finger family protein 0.0028 0.0049 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0089 0.0206
Echinococcus multilocularis Regulator of G protein signaling 20 0.0038 0.0086 0.0081
Brugia malayi von Willebrand factor type A domain containing protein 0.0049 0.0126 0.0377
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0249
Onchocerca volvulus 0.002 0.0018 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0037 0.0081 0.0237
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0049 0.0126 0.2838
Brugia malayi latrophilin 2 splice variant baaae 0.0032 0.0064 0.0185
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Trichomonas vaginalis DNA helicase recq1, putative 0.0065 0.0188 0.049
Plasmodium vivax thrombospondin-related anonymous protein 0.0049 0.0126 0.2838
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.015 0.0144
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0205 0.062
Echinococcus granulosus metabotropic glutamate receptor 2 0.008 0.0246 0.024
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.011 0.0321
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0081 0.0237
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0287 0.0756
Onchocerca volvulus 0.0038 0.0085 0.0215
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0037 0.0081 0.0237
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0037 0.0081 0.0237
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0112 0.0283
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0038 0.0085 0.0252
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0255 0.092 0.0915
Echinococcus multilocularis nAChR subunit 0.002 0.0018 0.0012
Echinococcus granulosus lamin dm0 0.0083 0.0258 0.0252
Schistosoma mansoni loxhd1 0.002 0.0014 0.0033
Loa Loa (eye worm) intermediate filament protein 0.0083 0.0258 0.0779
Loa Loa (eye worm) TK/ROR protein kinase 0.0024 0.003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0018 0.0007 0.0008
Trichomonas vaginalis hypothetical protein 0.0041 0.0096 0.024
Mycobacterium ulcerans aldehyde dehydrogenase 0.025 0.0899 1
Brugia malayi nuclear receptor NHR-88 0.0037 0.0081 0.0237
Toxoplasma gondii microneme protein MIC2 0.0049 0.0126 0.1263
Plasmodium falciparum cysteine repeat modular protein 1 0.0024 0.003 0.069
Brugia malayi nuclear hormone receptor 0.0037 0.0081 0.0237
Entamoeba histolytica recQ family helicase, putative 0.0044 0.0108 0.2762
Brugia malayi laminin-like protein K08C7.3 precursor 0.0054 0.0147 0.0441
Echinococcus multilocularis metabotropic glutamate receptor 2 0.008 0.0246 0.024
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0037
Schistosoma mansoni eyes absent homolog 0.0084 0.0262 0.0605
Brugia malayi Zona pellucida-like domain containing protein 0.0049 0.0126 0.0377
Echinococcus multilocularis regulator of G protein signaling 0.0038 0.0086 0.0081
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0063 0.1497
Loa Loa (eye worm) RecQ helicase 0.0065 0.0188 0.0564
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0082 0.0202
Loa Loa (eye worm) hypothetical protein 0.01 0.0323 0.0978
Brugia malayi hypothetical protein 0.0037 0.0082 0.0242
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0038 0.0085 0.0252
Brugia malayi hypothetical protein 0.0017 0.0006 0.0006
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0082 0.019
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0085 0.0267 0.7324
Brugia malayi nuclear receptor NHR-67 0.0017 0.0006 0.0006
Echinococcus multilocularis bloom syndrome protein 0.0065 0.0188 0.0183
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0122
Schistosoma mansoni cell polarity protein 0.0054 0.0147 0.0339
Brugia malayi Steroid receptor seven-up type 2 0.0037 0.0081 0.0237
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.1499 0.1494
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Loa Loa (eye worm) GABA receptor subunit 0.002 0.0018 0.0037
Onchocerca volvulus 0.0049 0.0126 0.0325
Loa Loa (eye worm) hypothetical protein 0.0084 0.0262 0.0791
Trichomonas vaginalis rotamase, putative 0.0032 0.0063 0.0151
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0018 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0231
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0153 0.0148
Echinococcus multilocularis glycine receptor subunit beta 0.0038 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Echinococcus granulosus transcription factor Dp 1 0.004 0.0093 0.0087
Toxoplasma gondii kringle domain-containing protein 0.0024 0.003 0.0183
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0231
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0007 0.0008
Echinococcus granulosus glycine receptor subunit alpha 1 0.0038 0.0085 0.008
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0038 0.0086 0.0249
Onchocerca volvulus Putative nachr subunit 0.0038 0.0085 0.0215
Schistosoma mansoni retinoic acid receptor RXR 0.0037 0.0081 0.0186
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0093 0.0087
Echinococcus multilocularis dual specificity 0.0085 0.0267 0.0261
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0112 0.0283
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0037 0.0081 0.0231
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0804 0.3031 0.3027
Loa Loa (eye worm) doublecortin family protein 0.002 0.0014 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0038 0.0085 0.0252
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0085 0.0264 0.0798
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0231
Brugia malayi A-kinase anchor protein 10, precursor 0.0038 0.0086 0.0255
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0017 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Trichomonas vaginalis rotamase, putative 0.0033 0.0066 0.016
Plasmodium vivax SET domain protein, putative 0.0124 0.0415 1
Schistosoma mansoni cpg binding protein 0.003 0.0055 0.0127
Loa Loa (eye worm) hypothetical protein 0.0039 0.0087 0.0251
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0164 0.1694
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.002 0.0142
Onchocerca volvulus 0.0051 0.0136 0.0352
Onchocerca volvulus 0.0038 0.0085 0.0215
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0038 0.0085 0.008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0053 0.1647
Entamoeba histolytica protein kinase, putative 0.0085 0.0267 0.7346
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0037 0.0081 0.0075
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0049 0.0126 0.2838
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0238 0.0854 0.2619
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Schistosoma mansoni ets-related 0.021 0.0745 0.172
Onchocerca volvulus 0.0049 0.0126 0.0324
Schistosoma mansoni acetylcholine receptor subunit beta 0.0018 0.0007 0.0015
Brugia malayi hypothetical protein 0.0084 0.0262 0.0797
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0415 0.4532
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Echinococcus granulosus FTZ F1 alpha 0.0037 0.0081 0.0075
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0038 0.0085 0.0252
Entamoeba histolytica hypothetical protein 0.0085 0.0267 0.7346
Schistosoma mansoni nuclear receptor 0.0017 0.0006 0.0014
Echinococcus granulosus neurogenic locus notch protein 0.0054 0.0147 0.0141
Onchocerca volvulus 0.0049 0.0126 0.0325
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.002 0.0039
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0014 0.0032
Entamoeba histolytica hypothetical protein 0.002 0.0018 0.0189
Schistosoma mansoni thyroid hormone receptor 0.0292 0.1062 0.2453
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0054 0.0147 0.0441
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0086 0.0081
Onchocerca volvulus 0.0083 0.0258 0.0683
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0025
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.002 0.0142
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0179
Brugia malayi phosphofructokinase 0.0109 0.036 0.1098
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0086 0.0816
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0039 0.0695
Schistosoma mansoni coup transcription factor 0.0037 0.0081 0.0186
Leishmania major hypothetical protein, conserved 0.0026 0.0039 0.0104
Loa Loa (eye worm) hypothetical protein 0.0143 0.0489 0.1491
Schistosoma mansoni nuclear receptor 0.0017 0.0006 0.0014
Mycobacterium ulcerans hypothetical protein 0.0021 0.002 0.0142
Echinococcus multilocularis lamin dm0 0.0083 0.0258 0.0252
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0038 0.0085 0.0197
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0038 0.0085 0.0252
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0085 0.0264 0.0798
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0026
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0108 0.0356 0.0822
Loa Loa (eye worm) hypothetical protein 0.0037 0.0082 0.0236
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0085 0.0267 0.7324
Brugia malayi Sulfatase family protein 0.0018 0.0008 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0049 0.0126 0.2838
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0086 0.02
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0039 0.073
Brugia malayi Fli-1 protein 0.021 0.0745 0.2286
Schistosoma mansoni hypothetical protein 0.0168 0.0585 0.1352
Schistosoma mansoni gabp alpha 0.0069 0.0204 0.0472
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0086 0.0255
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0025
Onchocerca volvulus Bile acid receptor homolog 0.0037 0.0081 0.0202
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0033 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0287 0.0756
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0082 0.1335
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0082 0.019
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0033 0.0084
Loa Loa (eye worm) hypothetical protein 0.0081 0.0252 0.0761
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0037 0.0081 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0213
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0014 0.0031
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0037 0.0081 0.0075
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.036 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0153 0.5223
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0082 0.0076
Brugia malayi von Willebrand factor type A domain containing protein 0.0049 0.0126 0.0377
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0037 0.0081 0.0237
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0093 0.0087
Onchocerca volvulus 0.0978 0.37 1
Onchocerca volvulus 0.0028 0.0049 0.0116
Leishmania major hypothetical protein, conserved 0.0027 0.0042 0.0138
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0039 0.073
Echinococcus multilocularis FTZ F1 alpha 0.0037 0.0081 0.0075
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0205 0.0199
Echinococcus multilocularis GA binding protein alpha chain 0.0069 0.0204 0.0199
Brugia malayi Pre-SET motif family protein 0.0124 0.0415 0.1269
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0049 0.0126 0.0371
Schistosoma mansoni nAChR subunit 0.0038 0.0085 0.0197
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0018 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0038 0.0086 0.0081
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0038 0.0085 0.0245
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0122 0.0364
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0018 0.0007 0.0002
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0038 0.0085 0.0252
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.036 0.0953
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0205 0.0614
Brugia malayi Cation transporter family protein 0.0038 0.0085 0.0252
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0038 0.0086 0.0081
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0122 0.0358
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0038 0.0085 0.0245
Echinococcus granulosus expressed protein 0.0746 0.2807 0.2802
Schistosoma mansoni acetylcholine receptor-related 0.0018 0.0007 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0415 0.0959
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0014 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0082 0.0202
Echinococcus granulosus nAChR subunit 0.0038 0.0085 0.008
Echinococcus granulosus nAChR subunit 0.002 0.0018 0.0012
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0038 0.0085 0.0197
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0084 0.0262 0.0256
Brugia malayi conserved hypotetical protein 0.0017 0.0006 0.0006
Echinococcus multilocularis geminin 0.0168 0.0585 0.058
Brugia malayi Ets-domain containing protein 0.0069 0.0204 0.0619
Echinococcus granulosus voltage dependent calcium channel subunit 0.119 0.4515 0.4512
Brugia malayi hypothetical protein 0.0253 0.091 0.2796
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0082 0.2034
Entamoeba histolytica hypothetical protein 0.0049 0.0126 0.3291
Entamoeba histolytica recQ family DNA helicase 0.002 0.0014 0.0082
Brugia malayi von Willebrand Factor 0.0049 0.0126 0.0377
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0153 0.0268
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.025 0.0899 0.0893
Treponema pallidum hypothetical protein 0.0049 0.0126 0.0215
Brugia malayi follicle stimulating hormone receptor 0.0238 0.0854 0.2624
Schistosoma mansoni survival motor neuron protein 0.0049 0.0126 0.029
Brugia malayi 6-phosphofructokinase 0.0109 0.036 0.1098
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0037 0.0081 0.0075
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0086 0.0255
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0007 0.0008
Brugia malayi von Willebrand factor type A domain containing protein 0.0049 0.0126 0.0377
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0153 0.1637
Loa Loa (eye worm) hypothetical protein 0.004 0.0093 0.0269
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0082 0.0076
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0038 0.0085 0.008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0038 0.0085 0.0252
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Echinococcus granulosus ecdysone induced protein 78C 0.0037 0.0081 0.0075
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0038 0.0085 0.0197
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0037 0.0081 0.0237
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.036 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0267 0.0617
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0038 0.0085 0.0197
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0037 0.0081 0.0237
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0053 0.0122
Brugia malayi 6-phosphofructokinase 0.0109 0.036 0.1098
Schistosoma mansoni blooms syndrome DNA helicase 0.0045 0.0113 0.0262
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.0018 0.0043
Schistosoma mansoni neurotransmitter gated ion channel 0.0018 0.0007 0.0015
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.025 0.0899 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0017 0.0006 0.0006
Loa Loa (eye worm) CUTiclin-Like family member 0.0049 0.0126 0.0371
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0053 0.0435
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0066 0.016
Brugia malayi von Willebrand factor type A domain containing protein 0.0049 0.0126 0.0377
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0205 0.5515
Schistosoma mansoni rotamase 0.0033 0.0066 0.0154
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.01 0.0323 0.0745
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0006 0.0006
Brugia malayi hypothetical protein 0.0018 0.0007 0.0008
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0038 0.0085 0.008
Onchocerca volvulus 0.0037 0.0081 0.0202
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0041 0.0095 0.2075
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0086 0.0081
Loa Loa (eye worm) hypothetical protein 0.0054 0.0147 0.0435
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0026
Entamoeba histolytica protein kinase, putative 0.0085 0.0267 0.7346
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0053 0.1647
Schistosoma mansoni DNA helicase recq1 0.0038 0.0086 0.02
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0153 0.1417
Echinococcus granulosus GA binding protein alpha chain 0.0069 0.0204 0.0199
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0037 0.0081 0.0186
Schistosoma mansoni lipoxygenase 0.002 0.0014 0.0033
Loa Loa (eye worm) abnormal epIthelia family member 0.0054 0.0147 0.0435
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0086 0.0271 0.0825
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0086 0.02
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.01 0.0323 0.0317
Entamoeba histolytica hypothetical protein 0.0038 0.0086 0.2154
Onchocerca volvulus Protein ultraspiracle homolog 0.0037 0.0081 0.0202
Onchocerca volvulus 0.002 0.0018 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0037 0.0081 0.0237
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0037 0.0081 0.0075
Loa Loa (eye worm) hypothetical protein 0.0059 0.0166 0.0494
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0082 0.1968
Brugia malayi Intermediate filament tail domain containing protein 0.0083 0.0258 0.0785
Schistosoma mansoni ap endonuclease 0.0056 0.0153 0.0355
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0854 0.0849
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0231
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.009 0.0287 0.0868
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0205 0.0473
Onchocerca volvulus 0.0038 0.0085 0.0215
Echinococcus granulosus serine:threonine protein kinase PLK1 0.009 0.0287 0.0281
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0038 0.0086 0.0213
Echinococcus multilocularis nAChR subunit 0.0038 0.0085 0.008
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0038 0.0085 0.0245
Brugia malayi nuclear hormone receptor family member nhr-6 0.0017 0.0006 0.0006
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0038 0.0086 0.02
Schistosoma mansoni hypothetical protein 0.0406 0.1499 0.3463
Onchocerca volvulus 0.0038 0.0085 0.0215
Loa Loa (eye worm) cytochrome P450 family protein 0.0073 0.0221 0.0665
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.008 0.0248 0.2692
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0122
Brugia malayi von Willebrand factor type A domain containing protein 0.0049 0.0126 0.0377
Schistosoma mansoni RAR-like nuclear receptor 0.0037 0.0081 0.0186
Loa Loa (eye worm) hypothetical protein 0.0026 0.0039 0.0103
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0249
Echinococcus multilocularis cpg binding protein 0.003 0.0055 0.0049
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0038 0.0086 0.3093
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0037 0.0081 0.0237
Schistosoma mansoni metabotropic glutamate receptor 0.008 0.0246 0.0569
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.036 0.395
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0038 0.0085 0.008
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0038 0.0086 0.0081
Brugia malayi Ets-domain containing protein 0.0069 0.0204 0.0619
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0122
Onchocerca volvulus 0.0018 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0037
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.036 1
Toxoplasma gondii exonuclease III APE 0.0056 0.0153 0.1574
Schistosoma mansoni kinase 0.0046 0.0117 0.027
Schistosoma mansoni laminin gamma-3 chain 0.0054 0.0147 0.0339
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0231
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0027 0.0042 0.0092
Trichomonas vaginalis DNA helicase recq, putative 0.0065 0.0188 0.049
Schistosoma mansoni tsg101-related 0.007 0.0208 0.048
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0086 0.0081
Brugia malayi intermediate filament protein 0.0083 0.0258 0.0785
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.0089 0.0083
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Echinococcus granulosus dnaJ subfamily B 0.0406 0.1499 0.1494
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0267 0.7346
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0415 0.0959
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0086 0.0081
Echinococcus multilocularis pikachurin 0.0054 0.0147 0.0141
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0018 0.0043
Loa Loa (eye worm) glutamate receptor 0.0038 0.0083 0.0239
Schistosoma mansoni nAChR subunit 0.0038 0.0085 0.0197
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0153 0.408
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0038 0.0085 0.0197
Brugia malayi steroid hormone receptor 0.0037 0.0081 0.0237
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0086 0.0081
Brugia malayi hypothetical protein 0.0019 0.0014 0.0031
Schistosoma mansoni rab6-interacting 0.002 0.0014 0.0033
Schistosoma mansoni DNA helicase recq5 0.0038 0.0086 0.02
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0248 1
Brugia malayi hypothetical protein 0.0018 0.0007 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0037 0.0081 0.0231
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0082 0.2671
Loa Loa (eye worm) hypothetical protein 0.0051 0.0136 0.0402
Entamoeba histolytica hypothetical protein 0.0037 0.0082 0.2037
Loa Loa (eye worm) hypothetical protein 0.01 0.0323 0.0978
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0037
Echinococcus granulosus lamin 0.0083 0.0258 0.0252
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.036 0.395
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0044
Echinococcus granulosus RUN 0.002 0.0014 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0037 0.0081 0.0237
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0126 0.0377
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.009 0.0287 0.0281
Onchocerca volvulus 0.0018 0.0007 0.0002
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0033 0.009
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0287 0.0756
Plasmodium falciparum thrombospondin-related anonymous protein 0.0049 0.0126 0.4788
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0037 0.0081 0.0186
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0063 0.0557
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0153 0.3561
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0153 0.0395
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.008 0.0248 0.6696
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0049 0.0126 0.4788
Onchocerca volvulus 0.0083 0.0258 0.0683
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0037
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0248 0.5848
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0082 0.0076
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.008 0.0248 0.0752
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0038 0.0085 0.0252
Loa Loa (eye worm) phosphofructokinase 0.0109 0.036 0.1092
Loa Loa (eye worm) hypothetical protein 0.0084 0.0262 0.0791
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0027 0.0042 0.0815
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0049 0.0126 0.1263
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0147 0.0435
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0287 0.0756
Brugia malayi von Willebrand factor type A domain containing protein 0.0049 0.0126 0.0377
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0069 0.0204 0.0613
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0038 0.0085 0.0252
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0287 0.0756
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0018 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.036 0.0953
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.025 0.0899 1
Echinococcus multilocularis RUN 0.002 0.0014 0.0008
Echinococcus granulosus tumor protein p63 0.035 0.1284 0.1278
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.036 0.0665
Brugia malayi nuclear receptor NHR-88 0.0017 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0049 0.0126 0.0291
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0119 0.0395 0.039
Loa Loa (eye worm) hypothetical protein 0.0117 0.039 0.1187
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0019 0.0014 0.0025
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.004 0.0092 0.0883
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0006 0.0014
Onchocerca volvulus 0.0049 0.0126 0.0325
Echinococcus multilocularis expressed protein 0.0746 0.2807 0.2802
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0108 0.2127
Echinococcus multilocularis lamin 0.0083 0.0258 0.0252
Schistosoma mansoni nAChR subunit 0.0038 0.0085 0.0197
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0086 0.0249
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0086 0.02
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0053 0.0435
Echinococcus multilocularis glycine receptor subunit beta 0.0038 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0089 0.0206
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0086 0.0081
Brugia malayi hypothetical protein 0.0049 0.0126 0.0377
Schistosoma mansoni lamin 0.0083 0.0258 0.0596
Brugia malayi ecdysone receptor 0.0017 0.0006 0.0006
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0085 0.0267 0.0807
Loa Loa (eye worm) fli-1 protein 0.021 0.0745 0.2281
Schistosoma mansoni nuclear receptor nhr-48 0.0017 0.0006 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0415 0.0959
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0037 0.0081 0.0075
Schistosoma mansoni lamin 0.0083 0.0258 0.0596
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0086 0.02
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0038 0.0085 0.0245
Loa Loa (eye worm) hypothetical protein 0.0658 0.2469 0.7608
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0085 0.0267 0.2726
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0063 0.1427
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0018 0.0007 0.0008
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0038 0.0086 0.0081
Onchocerca volvulus 0.002 0.0014 0.0023
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0082 0.0076
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0086 0.02
Brugia malayi hypothetical protein 0.0018 0.0007 0.0008
Brugia malayi hypothetical protein 0.0026 0.0039 0.011
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0014 0.0008
Echinococcus granulosus tissue type plasminogen activator 0.0024 0.003 0.0025
Echinococcus granulosus glycine receptor subunit beta 0.0038 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0249
Loa Loa (eye worm) hypothetical protein 0.0054 0.0147 0.0435
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.1142 0.4328 1
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.036 0.0354
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0038 0.0085 0.0252
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0231
Loa Loa (eye worm) LGC-31 protein 0.0038 0.0085 0.0245
Brugia malayi orphan nuclear receptor NR2E1 0.0017 0.0006 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0213
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0153 0.0395
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0014 0.0073
Brugia malayi von Willebrand factor type A domain containing protein 0.0049 0.0126 0.0377
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0038 0.0085 0.008
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0086 0.02
Brugia malayi hypothetical protein 0.0018 0.0007 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0037 0.0081 0.0237
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0037 0.0081 0.0231
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.0089 0.0257
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0108 0.0271
Echinococcus multilocularis tumor protein p63 0.035 0.1284 0.1278
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.01 0.0323 0.0745
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0124 0.0415 0.0959
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0038 0.0085 0.0252
Echinococcus multilocularis thyroid hormone receptor alpha 0.0292 0.1062 0.1056
Loa Loa (eye worm) hypothetical protein 0.008 0.0248 0.0746
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0082 0.0242
Schistosoma mansoni cpg binding protein 0.0028 0.0049 0.0112
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.0089 0.0263
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0038 0.0085 0.008
Echinococcus granulosus geminin 0.0168 0.0585 0.058
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0249
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0049 0.0126 0.0371
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.036 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0087 0.0251
Giardia lamblia Kinase, PLK 0.009 0.0287 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0122 0.0358
Schistosoma mansoni hypothetical protein 0.0168 0.0585 0.1352
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0037 0.0081 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0082 0.0202
Brugia malayi Doublecortin family protein 0.002 0.0014 0.0032
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0249
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0038 0.0085 0.008
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0018 0.0041
Brugia malayi Cation transporter family protein 0.0038 0.0085 0.0252
Schistosoma mansoni aldehyde dehydrogenase 0.025 0.0899 0.2077
Echinococcus granulosus cpg binding protein 0.003 0.0055 0.0049
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0086 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0122
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0017 0.0006 0.0014
Trichomonas vaginalis set domain proteins, putative 0.0978 0.37 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0037 0.0081 0.0186
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0038 0.0085 0.008
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0038 0.0085 0.008
Echinococcus multilocularis voltage dependent calcium channel subunit 0.119 0.4515 0.4512
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0153 0.4031
Mycobacterium ulcerans epimerase 0.0021 0.002 0.0142
Trypanosoma cruzi polo-like protein kinase, putative 0.009 0.0287 0.7893
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.036 0.1092
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0038 0.0085 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0213
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0083 0.0258 0.0779
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0038 0.0085 0.008
Brugia malayi Bloom's syndrome protein homolog 0.0065 0.0188 0.057
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0122 0.0364
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0086 0.0081
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0205 0.2007
Schistosoma mansoni nAChR subunit 0.0018 0.0007 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0026
Schistosoma mansoni ap endonuclease 0.0056 0.0153 0.0355
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0085 0.0267 0.7113
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0082 0.0596
Schistosoma mansoni hypothetical protein 0.002 0.0014 0.0033
Echinococcus multilocularis expressed protein 0.0033 0.0066 0.0061
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0038 0.0085 0.008
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0082 0.0076
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0024 0.003 0.0472
Schistosoma mansoni nuclear hormone receptor 0.0037 0.0081 0.0186
Schistosoma mansoni hypothetical protein 0.0255 0.092 0.2126
Echinococcus granulosus pikachurin 0.0054 0.0147 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0014 0.0031
Echinococcus granulosus leukotriene A 4 hydrolase 0.0231 0.0826 0.0821
Brugia malayi nuclear receptor RXR 0.0019 0.0014 0.0031
Schistosoma mansoni polycystin 1-related 0.002 0.0014 0.0033
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0038 0.0085 0.008
Giardia lamblia Sgs1 DNA helicase, putative 0.0038 0.0086 0.2824
Brugia malayi nuclear hormone receptor family member odr-7 0.0017 0.0006 0.0006
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0086 0.0816
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0037 0.0081 0.0075
Entamoeba histolytica hypothetical protein 0.0037 0.0082 0.2037
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0084 0.0262 0.0256
Loa Loa (eye worm) hypothetical protein 0.0288 0.1046 0.3213
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0037
Echinococcus granulosus histone lysine methyltransferase setb 0.0124 0.0415 0.041
Brugia malayi tailless protein 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0037 0.0081 0.0075
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0231
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0038 0.0086 0.0081
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0189 0.0436
Echinococcus granulosus glycine receptor subunit alpha 1 0.0038 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0025
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0576 0.2152 0.4971
Brugia malayi Protein kinase domain containing protein 0.0024 0.003 0.0082
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0053 0.1617
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0018 0.0041
Loa Loa (eye worm) ACC-1 protein 0.0038 0.0085 0.0245
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.011 0.0327
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.002 0.0018 0.0043
Schistosoma mansoni hypothetical protein 0.0037 0.0082 0.019
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0049 0.0126 0.0377
Brugia malayi hypothetical protein 0.0106 0.0347 0.1059
Schistosoma mansoni zinc finger protein 0.0017 0.0006 0.0014
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0037 0.0081 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0287 0.0663
Loa Loa (eye worm) hypothetical protein 0.0238 0.0854 0.2619
Brugia malayi laminin alpha chain 0.0054 0.0147 0.0441
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0037
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0038 0.0086 0.0081
Loa Loa (eye worm) ACC-1 protein 0.0038 0.0085 0.0245
Schistosoma mansoni hypothetical protein 0.0615 0.2302 0.532
Schistosoma mansoni nAChR subunit 0.0038 0.0085 0.0197
Onchocerca volvulus 0.0049 0.0126 0.0325
Loa Loa (eye worm) hypothetical protein 0.0527 0.1965 0.605
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.01 0.0323 0.0745
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0018 0.0007 0.0002
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0153 0.0462
Schistosoma mansoni serine-rich repeat protein 0.0615 0.2302 0.532
Chlamydia trachomatis endonuclease IV 0.008 0.0248 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0093 0.0087
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0153 0.4031
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0049 0.0132
Echinococcus granulosus collagen alpha 1VII chain 0.0049 0.0126 0.012
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0086 0.0081
Entamoeba histolytica hypothetical protein 0.0038 0.0086 0.2154
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0053 0.0074
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0053 0.1025
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0213
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0019 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.1371 0.521 1
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0231 0.0826 0.2534
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0063 0.1427
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0249
Echinococcus granulosus glycine receptor subunit beta 0.0038 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0037 0.0081 0.0237
Onchocerca volvulus 0.0124 0.0415 0.1108
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0126 0.3291
Brugia malayi EGF-like domain containing protein 0.0054 0.0147 0.0441
Onchocerca volvulus 0.0038 0.0085 0.0215
Loa Loa (eye worm) hypothetical protein 0.0124 0.0415 0.1264
Echinococcus granulosus Regulator of G protein signaling 20 0.0038 0.0086 0.0081
Brugia malayi hypothetical protein 0.0018 0.0008 0.0011
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0037 0.0081 0.0202
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0037 0.0081 0.0075
Brugia malayi excitatory GABA receptor EXP-1A 0.0038 0.0085 0.0252
Brugia malayi Kringle domain containing protein 0.0024 0.003 0.0082
Loa Loa (eye worm) steroid hormone receptor 0.0037 0.0081 0.0231
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0038 0.0085 0.0252
Brugia malayi hypothetical protein 0.0238 0.0854 0.2624
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0037 0.0081 0.0186
Brugia malayi Zona pellucida-like domain containing protein 0.0049 0.0126 0.0377
Brugia malayi PXA domain containing protein 0.0038 0.0086 0.0255
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0255 0.092 0.0915
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0086 0.02
Schistosoma mansoni nAChR subunit 0.0038 0.0085 0.0197
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0037 0.0081 0.0231
Schistosoma mansoni tsg101-related 0.0057 0.0159 0.0367
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.009 0.0287 0.2953
Loa Loa (eye worm) glutamate receptor 0.0095 0.0306 0.0926
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.036 0.3791
Brugia malayi hypothetical protein 0.0018 0.0007 0.0008
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.036 0.0831
Schistosoma mansoni rab6-interacting 0.002 0.0014 0.0033
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0038 0.0085 0.008
Treponema pallidum 76K protein 0.0049 0.0126 0.0215
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0126 0.3291
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0108 0.2702
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0053 0.0435
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.0089 0.0257
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0019 0.0014 0.0032
Schistosoma mansoni neurotransmitter gated ion channel 0.0018 0.0007 0.0015
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0086 0.0081
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0082 0.1968
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0038 0.0085 0.0245
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0049 0.0126 0.012
Loa Loa (eye worm) acetylcholine receptor protein 0.0018 0.0007 0.0002
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0153 0.5
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0038 0.0085 0.008
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0086 0.0081
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0037 0.0081 0.0186
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0205 0.5162
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0082 0.019
Brugia malayi photoreceptor-specific nuclear receptor 0.0037 0.0081 0.0237
Schistosoma mansoni cpg binding protein 0.003 0.0055 0.0127
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0038 0.0085 0.0252
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0037 0.0081 0.0075
Brugia malayi hypothetical protein 0.002 0.0014 0.0032
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0086 0.02
Onchocerca volvulus 0.002 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0049 0.0126 0.2838
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0063 0.0752
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0066 0.0187
Brugia malayi hypothetical protein 0.0288 0.1046 0.3217
Echinococcus granulosus glycine receptor subunit alpha 1 0.0038 0.0085 0.008
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0019 0.0014 0.0008
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0018 0.0007 0.0001
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0153 0.3519
Brugia malayi Pre-SET motif family protein 0.086 0.3244 1
Brugia malayi ecdysteroid receptor 0.0037 0.0081 0.0237
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0014 0.0033
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Schistosoma mansoni lipoxygenase 0.0055 0.015 0.0346
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0014 0.0008
Onchocerca volvulus 0.0049 0.0126 0.0325
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0205 0.5552
Schistosoma mansoni nAChR subunit 0.0038 0.0085 0.0197
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0039 0.1077
Onchocerca volvulus Serine\/threonine kinase homolog 0.009 0.0287 0.076
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0038 0.0085 0.0245
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0018 0.0007 0.0001
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0057 0.0159 0.4231
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0082 0.0076
Brugia malayi hypothetical protein 0.002 0.0014 0.0032
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0153 0.0456
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0038 0.0085 0.0252
Echinococcus granulosus dual specificity 0.0085 0.0267 0.0261
Loa Loa (eye worm) PXA domain-containing protein 0.0038 0.0086 0.0249
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0126 0.0376
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0018 0.0007 0.0001
Echinococcus granulosus slit 2 protein 0.0054 0.0147 0.0141
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0018 0.0007 0.0008
Entamoeba histolytica elongation factor-2 kinase, putative 0.0049 0.0126 0.3291
Brugia malayi Metabotropic glutamate receptor precursor. 0.0095 0.0306 0.0932
Schistosoma mansoni thyroid hormone receptor 0.0292 0.1062 0.2453
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0038 0.0085 0.008
Entamoeba histolytica hypothetical protein 0.0037 0.0082 0.2037
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0854 0.0849
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0089 0.0206
Entamoeba histolytica hypothetical protein 0.0037 0.0082 0.2037
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0082 0.0076
Echinococcus multilocularis voltage dependent calcium channel subunit 0.2617 1 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0037 0.0081 0.0186
Brugia malayi Cation transporter family protein 0.0038 0.0085 0.0252
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0014 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0122
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0038 0.0085 0.008
Brugia malayi Cytochrome P450 family protein 0.0073 0.0221 0.0671
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0086 0.02
Echinococcus granulosus metabotropic glutamate receptor 5 0.0117 0.039 0.0385
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0018 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Brugia malayi Protein kinase domain containing protein 0.0085 0.0267 0.0813
Schistosoma mansoni aldehyde dehydrogenase 0.025 0.0899 0.2077
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.01 0.0323 0.0317
Schistosoma mansoni metabotropic glutamate receptor 0.0046 0.0118 0.0272
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0037 0.0081 0.0075
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0039 0.1077
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0287 0.0756
Onchocerca volvulus 0.0018 0.0007 0.0002
Schistosoma mansoni nAChR subunit 0.0038 0.0085 0.0197
Mycobacterium ulcerans endonuclease IV 0.008 0.0248 0.2692
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0371
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0059 0.0167 0.6564
Mycobacterium ulcerans aldehyde dehydrogenase 0.025 0.0899 1
Onchocerca volvulus 0.0049 0.0126 0.0325
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0153 0.1637
Echinococcus multilocularis ecdysone induced protein 78C 0.0037 0.0081 0.0075
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.036 1
Echinococcus multilocularis musashi 0.0083 0.0258 0.0252
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0245
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.036 0.0831
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.086 0.3244 1
Brugia malayi Cache domain containing protein 0.0527 0.1965 0.6052
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0063 0.0381
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.036 0.1092
Loa Loa (eye worm) hypothetical protein 0.0084 0.0262 0.0791
Brugia malayi von Willebrand factor type A domain containing protein 0.0049 0.0126 0.0377
Echinococcus multilocularis tissue type plasminogen activator 0.0024 0.003 0.0025
Echinococcus granulosus bloom syndrome protein 0.0065 0.0188 0.0183
Schistosoma mansoni nAChR subunit 0.0018 0.0007 0.0015
Echinococcus multilocularis neurogenic locus notch protein 0.0054 0.0147 0.0141
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0025
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0124 0.0415 0.041
Toxoplasma gondii aldehyde dehydrogenase 0.025 0.0899 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0415 0.041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0002
Toxoplasma gondii endonuclease IV APN 0.008 0.0248 0.2637
Entamoeba histolytica hypothetical protein 0.0038 0.0086 0.2154
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.0287 0.791
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.015 0.0144
Echinococcus granulosus intermediate filament protein 0.0083 0.0258 0.0252
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0038 0.0085 0.008
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.0089 0.0083

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 93 uM Binding affinity to Tsg101 (unknown origin) ChEMBL. 18083557
IC50 (binding) = 93 uM Binding affinity to Tsg101 (unknown origin) ChEMBL. 18083557

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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