Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cpg binding protein | 0.0094 | 0.0488 | 0.0688 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0053 | 0.0249 | 0.4636 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0493 | 0.1343 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0036 | 0.0147 | 0.0207 |
Schistosoma mansoni | bromodomain containing protein | 0.0138 | 0.075 | 0.1058 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0069 | 0.034 | 0.0887 |
Schistosoma mansoni | tsg101-related | 0.0057 | 0.0268 | 0.0378 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0186 | 0.1032 | 0.1454 |
Echinococcus multilocularis | Kelch repeat type 1 | 0.0093 | 0.0481 | 0.0678 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0047 | 0.0212 | 0.0298 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.034 | 0.0479 |
Mycobacterium tuberculosis | RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. | 0.1321 | 0.7739 | 0.7729 |
Echinococcus granulosus | transcription factor Dp 1 | 0.004 | 0.0168 | 0.0237 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqF | 0.0062 | 0.0302 | 0.0256 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0082 | 0.0419 | 0.059 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0036 | 0.0147 | 0.2807 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0071 | 0.0352 | 0.0496 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0047 | 0.0662 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0038 | 0.0156 | 0.022 |
Trypanosoma brucei | polo-like protein kinase | 0.0093 | 0.0483 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0053 | 0.0249 | 0.0351 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0203 | 0.0286 |
Schistosoma mansoni | kinase | 0.0048 | 0.0214 | 0.0301 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0053 | 0.0249 | 0.0351 |
Trypanosoma cruzi | Vps23 core domain containing protein, putative | 0.0022 | 0.0061 | 0.0338 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0047 | 0.0212 | 0.0553 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0025 | 0.0035 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0071 | 0.0352 | 0.0947 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0249 | 0.4636 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.004 | 0.0168 | 0.0237 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0047 | 0.0066 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0203 | 0.0286 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0071 | 0.0352 | 0.0496 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0093 | 0.0483 | 0.068 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0047 | 0.0066 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0242 | 0.1361 | 0.3778 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0047 | 0.0066 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0689 | 0.097 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0141 | 0.2683 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0206 | 0.3664 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0085 | 0.0436 | 0.1181 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0047 | 0.0751 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.0147 | 0.0207 |
Wolbachia endosymbiont of Brugia malayi | replicative DNA helicase | 0.0382 | 0.2193 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0203 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0441 | 0.1196 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0689 | 0.097 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.003 | 0.0042 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0689 | 0.097 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0069 | 0.0338 | 0.6683 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0483 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0212 | 0.0298 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0338 | 0.0476 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.034 | 0.0479 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0689 | 0.097 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0501 | 0.2895 | 0.8932 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0047 | 0.0212 | 0.0298 |
Echinococcus multilocularis | smad | 0.0016 | 0.003 | 0.0042 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0069 | 0.1148 |
Schistosoma mansoni | tsg101-related | 0.0046 | 0.0207 | 0.0291 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.0147 | 0.0207 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0037 | 0.0153 | 0.0388 |
Mycobacterium ulcerans | lipoprotein LpqF | 0.0062 | 0.0302 | 0.08 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0036 | 0.0147 | 0.0207 |
Loa Loa (eye worm) | fli-1 protein | 0.0215 | 0.1206 | 0.3344 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0249 | 0.4637 |
Mycobacterium ulcerans | class a beta-lactamase, BlaC | 0.013 | 0.0701 | 0.2055 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0141 | 0.0199 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0047 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0291 | 0.0776 |
Treponema pallidum | replicative DNA helicase (dnaB) | 0.0382 | 0.2193 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0047 | 0.0751 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0156 | 0.0397 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0025 | 0.0035 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0203 | 0.0286 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0083 | 0.0833 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0025 | 0.0035 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0224 | 0.0561 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.003 | 0.0014 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Schistosoma mansoni | cpg binding protein | 0.0085 | 0.0436 | 0.0614 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0082 | 0.0419 | 0.1109 |
Echinococcus multilocularis | tar DNA binding protein | 0.0128 | 0.0689 | 0.097 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0036 | 0.0147 | 0.0343 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0052 | 0.0242 | 0.0342 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0123 | 0.0174 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0023 | 0.0069 | 0.0023 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0069 | 0.034 | 0.6726 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Brugia malayi | hypothetical protein | 0.0296 | 0.1684 | 0.4668 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0038 | 0.0156 | 0.022 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.003 | 0.0014 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0021 | 0.0057 | 0.0081 |
Brugia malayi | Bromodomain containing protein | 0.0163 | 0.0897 | 0.2453 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0082 | 0.0419 | 0.059 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.025 | 0.0661 |
Echinococcus multilocularis | tumor susceptibility gene 101 protein | 0.0068 | 0.0335 | 0.0473 |
Leishmania major | hypothetical protein, conserved | 0.0032 | 0.0123 | 0.1759 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0352 | 0.0921 |
Loa Loa (eye worm) | TAR-binding protein | 0.0128 | 0.0689 | 0.1891 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.003 | 0.0042 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.003 | 0.011 | 0.024 |
Chlamydia trachomatis | replicative DNA helicase | 0.0382 | 0.2193 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0338 | 0.0915 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0083 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.034 | 0.6726 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.003 | 0.0042 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0203 | 0.0286 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0141 | 0.0199 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0047 | 0.0066 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0044 | 0.019 | 0.0492 |
Entamoeba histolytica | tumor susceptibility gene 101 protein, putative | 0.0046 | 0.0207 | 0.4088 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0047 | 0.0751 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0047 | 0.0066 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0249 | 0.4637 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0206 | 0.3664 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.003 | 0.0042 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0203 | 0.0501 |
Schistosoma mansoni | bromodomain containing protein | 0.0014 | 0.0015 | 0.0021 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0224 | 0.0588 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0076 | 0.0381 | 0.0536 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0338 | 0.0915 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0212 | 0.0526 |
Trypanosoma brucei | ISWI complex protein | 0.0032 | 0.0123 | 0.2378 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0093 | 0.0483 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0025 | 0.0035 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0026 | 0.0088 | 0.0124 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0147 | 0.2297 |
Brugia malayi | hypothetical protein | 0.0016 | 0.003 | 0.0014 |
Echinococcus granulosus | muscleblind protein | 0.0617 | 0.3578 | 0.5042 |
Echinococcus granulosus | dnaJ subfamily B | 0.1212 | 0.7097 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0053 | 0.0249 | 0.5038 |
Trypanosoma brucei | protein kinase, putative | 0.0053 | 0.0249 | 0.5038 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.003 | 0.0043 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.003 | 0.0042 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0141 | 0.0199 |
Echinococcus multilocularis | zinc finger protein | 0.0046 | 0.0205 | 0.0289 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0047 | 0.0751 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0128 | 0.0689 | 0.1891 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0021 | 0.0057 | 0.0081 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0036 | 0.0145 | 0.0205 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0093 | 0.048 | 0.0676 |
Trypanosoma cruzi | ISWI complex protein | 0.0032 | 0.0123 | 0.1759 |
Schistosoma mansoni | myst-related protein | 0.0014 | 0.0016 | 0.0022 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0483 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0051 | 0.0234 | 0.0614 |
Giardia lamblia | Kinase, PLK | 0.0093 | 0.0483 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0462 | 0.2666 | 0.3757 |
Brugia malayi | TAR-binding protein | 0.0128 | 0.0689 | 0.1868 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0052 | 0.0242 | 0.0342 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.1684 | 0.4683 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.025 | 0.0634 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0147 | 0.2876 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.003 | 0.0043 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0249 | 0.4636 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0053 | 0.0249 | 0.0351 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0147 | 0.2299 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0338 | 0.0476 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.0483 | 1 |
Schistosoma mansoni | tsg101-related | 0.0057 | 0.0268 | 0.0378 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0249 | 0.4637 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0212 | 0.0553 |
Mycobacterium tuberculosis | Class a beta-lactamase BlaC | 0.013 | 0.0701 | 0.0658 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0132 | 0.0329 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0036 | 0.0147 | 0.2299 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0083 | 0.1521 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0047 | 0.0003 |
Brugia malayi | MAP kinase sur-1 | 0.0053 | 0.0249 | 0.063 |
Echinococcus granulosus | tar DNA binding protein | 0.0128 | 0.0689 | 0.097 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0083 | 0.0833 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0083 | 0.0161 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.018 | 0.0999 | 0.1408 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0689 | 0.097 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0132 | 0.0186 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0069 | 0.0338 | 0.0476 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.034 | 0.0479 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0036 | 0.0145 | 0.0205 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0036 | 0.0147 | 0.2297 |
Brugia malayi | PHD-finger family protein | 0.0057 | 0.0272 | 0.0695 |
Loa Loa (eye worm) | RNA binding protein | 0.0128 | 0.0689 | 0.1891 |
Brugia malayi | Fli-1 protein | 0.0215 | 0.1206 | 0.3325 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.025 | 0.0353 |
Trypanosoma cruzi | ISWI complex protein | 0.0032 | 0.0123 | 0.1759 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0053 | 0.0249 | 0.4636 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0462 | 0.2666 | 0.3757 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0141 | 0.2683 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0083 | 0.0192 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.003 | 0.0014 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0462 | 0.2666 | 0.3757 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.003 | 0.0042 |
Schistosoma mansoni | zinc finger protein | 0.0032 | 0.0123 | 0.0174 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0093 | 0.048 | 0.0676 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.025 | 0.0661 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0021 | 0.0057 | 0.0081 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0483 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0093 | 0.0483 | 0.1288 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0352 | 0.0921 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0083 | 0.0164 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0021 | 0.0057 | 0.0081 |
Brugia malayi | CXXC zinc finger family protein | 0.0085 | 0.0436 | 0.1156 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0012 | 0.0005 | 0.0007 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0082 | 0.0419 | 0.059 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0186 | 0.1032 | 0.1454 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.025 | 0.0353 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0212 | 0.0526 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0047 | 0.0751 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0023 | 0.0069 | 0.0071 |
Echinococcus granulosus | zinc finger protein | 0.0046 | 0.0205 | 0.0289 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0083 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0249 | 0.4637 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0128 | 0.0689 | 0.1868 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0083 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0617 | 0.3578 | 0.5042 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.034 | 0.6726 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0147 | 0.0371 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0025 | 0.0035 |
Brugia malayi | Bromodomain containing protein | 0.0081 | 0.041 | 0.1085 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0053 | 0.0249 | 0.4636 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0083 | 0.0833 |
Echinococcus granulosus | tumor susceptibility gene 101 protein | 0.0068 | 0.0335 | 0.0473 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0335 | 0.0874 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.003 | 0.0042 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0038 | 0.0156 | 0.022 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0131 | 0.0706 | 0.0995 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0069 | 0.0071 |
Trypanosoma brucei | beta lactamase | 0.0062 | 0.0302 | 0.6159 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0036 | 0.0145 | 0.0205 |
Schistosoma mansoni | hypothetical protein | 0.0093 | 0.0481 | 0.0678 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0338 | 0.0915 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0025 | 0.0035 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.003 | 0.0042 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0047 | 0.0066 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0025 | 0.0035 |
Schistosoma mansoni | ets-related | 0.0215 | 0.1206 | 0.17 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.025 | 0.0353 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0335 | 0.09 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0141 | 0.2683 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQF | 0.0062 | 0.0302 | 0.0734 |
Brugia malayi | MH2 domain containing protein | 0.0242 | 0.1361 | 0.376 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0047 | 0.0003 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0047 | 0.0061 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0047 | 0.0212 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0047 | 0.009 |
Leishmania major | hypothetical protein, conserved | 0.0022 | 0.0061 | 0.0338 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0025 | 0.0035 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.034 | 0.0913 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0053 | 0.0249 | 0.0351 |
Onchocerca volvulus | 0.0082 | 0.0419 | 0.1409 | |
Schistosoma mansoni | cpg binding protein | 0.0094 | 0.0488 | 0.0688 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0093 | 0.048 | 0.0676 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0023 | 0.0069 | 0.0521 |
Schistosoma mansoni | smad | 0.0016 | 0.003 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0224 | 0.0588 |
Echinococcus multilocularis | dnaJ subfamily B | 0.1212 | 0.7097 | 1 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.034 | 0.6972 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.0815 | 0.2245 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0203 | 0.0286 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0053 | 0.0249 | 0.4636 |
Brugia malayi | Cytochrome P450 family protein | 0.0051 | 0.0234 | 0.0587 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0483 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0053 | 0.0249 | 0.4636 |
Echinococcus granulosus | kelch ECH associated protein 1 | 0.0093 | 0.048 | 0.0676 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.003 | 0.0014 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0026 | 0.0088 | 0.0124 |
Echinococcus granulosus | geminin | 0.0166 | 0.0914 | 0.1288 |
Onchocerca volvulus | 0.0085 | 0.0436 | 0.1522 | |
Brugia malayi | Smad1 | 0.0016 | 0.003 | 0.0014 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0036 | 0.0147 | 0.0207 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0025 | 0.0029 |
Mycobacterium leprae | PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase | 0.0382 | 0.2193 | 0.6714 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0166 | 0.0915 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.0026 | 0.0088 | 0.0207 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0047 | 0.0066 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0025 | 0.0035 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0036 | 0.0147 | 0.2299 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0242 | 0.1361 | 0.3778 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0053 | 0.0249 | 0.2122 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0069 | 0.0338 | 0.0293 |
Schistosoma mansoni | Replicative DNA helicase | 0.0382 | 0.2193 | 0.3091 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0038 | 0.0156 | 0.022 |
Echinococcus multilocularis | cpg binding protein | 0.0094 | 0.0488 | 0.0688 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0141 | 0.0327 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0411 | 0.1113 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.025 | 0.0353 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0203 | 0.0529 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0093 | 0.0483 | 1 |
Mycobacterium ulcerans | replicative DNA helicase DnaB | 0.0382 | 0.2193 | 0.6737 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0052 | 0.0242 | 0.0342 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0069 | 0.0338 | 0.3177 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.003 | 0.0042 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.0147 | 0.0207 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0093 | 0.0483 | 0.1314 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0076 | 0.0381 | 0.0536 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0212 | 0.0298 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0047 | 0.0212 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0025 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0617 | 0.3578 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0141 | 0.2683 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0025 | 0.0035 |
Echinococcus multilocularis | muscleblind protein | 0.0617 | 0.3578 | 0.5042 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0093 | 0.0483 | 0.068 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0132 | 0.0301 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.0483 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0617 | 0.3578 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.0033 | 0.0129 | 0.1886 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.025 | 0.0353 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0224 | 0.0561 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0419 | 0.1135 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0483 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0141 | 0.0199 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0131 | 0.0706 | 0.0995 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0036 | 0.0145 | 0.0205 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0483 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0093 | 0.0483 | 0.068 |
Schistosoma mansoni | hypothetical protein | 0.0287 | 0.1629 | 0.2295 |
Schistosoma mansoni | gabp alpha | 0.0071 | 0.0352 | 0.0496 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0036 | 0.0147 | 0.2297 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0047 | 0.009 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0914 | 0.1288 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0047 | 0.0061 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0069 | 0.7976 |
Loa Loa (eye worm) | twinkle helicase | 0.0109 | 0.0578 | 0.1582 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0047 | 0.0212 | 0.0298 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.019 | 0.0268 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0203 | 0.0286 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0036 | 0.0147 | 0.0207 |
Mycobacterium tuberculosis | UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) | 0.0558 | 0.3233 | 0.3201 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0093 | 0.0483 | 0.1842 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 0.0249 | 0.0351 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0053 | 0.0249 | 0.0657 |
Echinococcus multilocularis | geminin | 0.0166 | 0.0914 | 0.1288 |
Trypanosoma brucei | Vps23 core domain containing protein, putative | 0.0022 | 0.0061 | 0.1064 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0047 | 0.0066 |
Schistosoma mansoni | zinc finger protein | 0.0046 | 0.0205 | 0.0289 |
Schistosoma mansoni | myst-related protein | 0.0014 | 0.0016 | 0.0022 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0047 | 0.0751 |
Echinococcus granulosus | smad | 0.0016 | 0.003 | 0.0042 |
Brugia malayi | RNA binding protein | 0.0128 | 0.0689 | 0.1868 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.003 | 0.0043 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0069 | 0.034 | 0.6942 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0914 | 0.1288 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.003 | 0.0042 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0802 | 0.4676 | 0.659 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.003 | 0.0042 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0147 | 0.2297 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0021 | 0.0057 | 0.0081 |
Mycobacterium ulcerans | UDP-galactopyranose mutase Glf | 0.0558 | 0.3233 | 1 |
Mycobacterium leprae | Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) | 0.0558 | 0.3233 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0069 | 0.1233 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0069 | 0.0338 | 0.0476 |
Echinococcus granulosus | cpg binding protein | 0.0094 | 0.0488 | 0.0688 |
Echinococcus granulosus | neuropeptide s receptor | 0.0462 | 0.2666 | 0.3757 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.0147 | 0.0207 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0093 | 0.048 | 0.0676 |
Loa Loa (eye worm) | hypothetical protein | 0.0617 | 0.3578 | 1 |
Onchocerca volvulus | 0.0296 | 0.1684 | 1 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0483 | 1 |
Schistosoma mansoni | hypothetical protein | 0.1212 | 0.7097 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 2 nM | Inhibition of human 11beta HSD in HEK293 cells by SPA method | ChEMBL. | 18485702 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.