Detailed information for compound 627711

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 284.325 | Formula: C13H14F2N2OS
  • H donors: 0 H acceptors: 1 LogP: 3.53 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCn1c(=NC(=O)C(C)C)sc2c1c(F)cc(c2)F
  • InChi: 1S/C13H14F2N2OS/c1-4-17-11-9(15)5-8(14)6-10(11)19-13(17)16-12(18)7(2)3/h5-7H,4H2,1-3H3/b16-13-
  • InChiKey: OBDOCXPZZPRNQU-SSZFMOIBSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0109 1
Brugia malayi hypothetical protein 0.0021 0.0078 0.0078
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0045 0.003
Echinococcus multilocularis muscleblind protein 1 0.1251 1 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.1573 0.1573
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0245 0.088
Loa Loa (eye worm) beta-lactamase 0.0036 0.0196 0.0196
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0047 0.0221
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0047 0.0221
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0126 0.0921 0.0907
Brugia malayi hypothetical protein 0.0074 0.0505 0.0505
Onchocerca volvulus Huntingtin homolog 0.0256 0.1974 1
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0046 0.028 0.3306
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0046 0.028 0.028
Schistosoma mansoni zinc finger protein 0.0019 0.0065 0.0273
Brugia malayi CHD4 protein 0.0013 0.0015 0.0015
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0196 0.0622
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0126 0.0921 0.0907
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0208
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0386 0.0372
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0059 0.0049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0047 0.0221
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.043 0.2263
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0045 0.0163
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.0098
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0047 0.0053
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.0754 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.002 0.0068 0.0068
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0059 0.0388
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0167 0.0153
Schistosoma mansoni hypothetical protein 0.0069 0.0468 0.2469
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0059 0.0049
Echinococcus granulosus RUN 0.0021 0.0078 0.0063
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.0819 0.3137
Echinococcus multilocularis pyruvate kinase 0.0026 0.0119 0.0104
Loa Loa (eye worm) hypothetical protein 0.0047 0.0284 0.0284
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0109 0.027
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0046 0.028 0.0958
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0047 0.0221
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0046 0.028 0.0958
Brugia malayi Pre-SET motif family protein 0.003 0.0147 0.0147
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.0819 0.2979
Schistosoma mansoni rab6-interacting 0.0021 0.0078 0.0342
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0046 0.028 0.0942
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0047 0.002
Mycobacterium leprae Probable lipase LipE 0.0036 0.0196 0.0406
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0175 0.0514
Onchocerca volvulus 0.0036 0.0196 0.0626
Schistosoma mansoni ap endonuclease 0.0019 0.0059 0.024
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0208
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0505 0.0491
Mycobacterium ulcerans L-lysine aminotransferase 0.0046 0.028 0.0942
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0047 0.0221
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0059 0.0067
Schistosoma mansoni hypothetical protein 0.0029 0.0142 0.0691
Brugia malayi Bromodomain containing protein 0.0074 0.0508 0.0508
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0196 0.0622
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0109 0.0252
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0109 0.0252
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0175 0.2134
Echinococcus granulosus ornithine aminotransferase 0.0046 0.028 0.0265
Echinococcus multilocularis peregrin 0.0031 0.0161 0.0146
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0059 0.0059
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0068 0.0512
Toxoplasma gondii thioredoxin reductase 0.0049 0.0308 0.3704
Mycobacterium ulcerans hypothetical protein 0.0324 0.2519 1
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0046 0.028 1
Mycobacterium tuberculosis Probable aminotransferase 0.0324 0.2519 1
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0505 0.2674
Schistosoma mansoni loxhd1 0.0021 0.0078 0.0342
Loa Loa (eye worm) hypothetical protein 0.1251 1 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0672 0.0658
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0046 0.028 0.0958
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0047 0.0387
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0167 0.0167
Brugia malayi jmjC domain containing protein 0.0095 0.0672 0.0672
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0047 0.0032
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0047 0.0053
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0221 0.0755
Echinococcus multilocularis ornithine aminotransferase 0.0046 0.028 0.0265
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.024 0.1848 0.1848
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0047 0.0221
Onchocerca volvulus 0.0036 0.0196 0.0626
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0105 0.0754 1
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0468 0.0468
Loa Loa (eye worm) glutathione reductase 0.0049 0.0308 0.0308
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0175 0.0175
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0046 0.028 0.0942
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.007 0.0474 0.0474
Echinococcus multilocularis zinc finger protein 0.0019 0.0065 0.005
Loa Loa (eye worm) hypothetical protein 0.0039 0.0221 0.0221
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0206 0.1042
Brugia malayi glutathione reductase 0.0049 0.0308 0.0308
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0308 0.3831
Entamoeba histolytica hypothetical protein 0.0074 0.0505 1
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0078 0.0063
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0466 0.0466
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0754 0.4029
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0167 0.0153
Echinococcus granulosus pyruvate kinase 0.0033 0.0175 0.0161
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.043 0.1549
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0109 0.2681
Plasmodium falciparum ornithine aminotransferase 0.0046 0.028 0.8926
Schistosoma mansoni hypothetical protein 0.0015 0.0031 0.0087
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.005 0.0181
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0068 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0221 0.0704
Loa Loa (eye worm) hypothetical protein 0.1251 1 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0142 0.0127
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0196 0.0182
Echinococcus multilocularis RUN 0.0021 0.0078 0.0063
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0308 0.0293
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0142 0.1359
Mycobacterium ulcerans beta-lactamase 0.0036 0.0196 0.0605
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0046 0.028 0.075
Echinococcus multilocularis mitogen activated protein kinase 0.0105 0.0754 0.074
Echinococcus granulosus geminin 0.0168 0.1264 0.1251
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.1791 0.1779
Echinococcus granulosus dna polymerase kappa 0.002 0.0068 0.0053
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0046 0.028 0.0958
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.013 0.0335
Onchocerca volvulus Huntingtin homolog 0.0256 0.1974 1
Echinococcus multilocularis ornithine aminotransferase 0.0046 0.028 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.013 0.0335
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0046 0.028 0.1443
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0109 0.1085
Echinococcus granulosus zinc finger protein 0.0019 0.0065 0.005
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0078 0.0063
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0078 0.1232
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0466 0.1695
Mycobacterium ulcerans acetylornithine aminotransferase 0.0046 0.028 0.0942
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0324 0.2519 1
Leishmania major hypothetical protein, conserved 0.0036 0.0196 0.2292
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0167 0.0153
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0109 0.0046
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0098 0.0208
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0059 0.0514
Schistosoma mansoni DNA polymerase eta 0.002 0.0068 0.0289
Plasmodium falciparum thioredoxin reductase 0.0017 0.0047 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0284 0.1466
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0046 0.028 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.005 0.0031
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.005
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0074 0.0074
Brugia malayi PHD-finger family protein 0.0025 0.0108 0.0108
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0308 0.0293
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0059 0.0388
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0047 0.002
Toxoplasma gondii ABC1 family protein 0.0036 0.0196 0.2133
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0098
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0089 0.0403
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0754 0.2859
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0196 0.0605
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0105 0.0754 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0068 0.0289
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0105 0.0754 0.0754
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0068 0.0085
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0105 0.0754 1
Brugia malayi Doublecortin family protein 0.0021 0.0078 0.0078
Schistosoma mansoni pyruvate kinase 0.0017 0.0045 0.0166
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0047 0.0387
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0196 0.0406
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0206 0.1042
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0622 0.3313
Brugia malayi PHD-finger family protein 0.0029 0.0142 0.0142
Brugia malayi hypothetical protein 0.0233 0.1791 0.1791
Brugia malayi Thioredoxin reductase 0.0049 0.0308 0.0308
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0175 0.0175
Echinococcus granulosus mitogen activated protein kinase 3 0.0105 0.0754 0.074
Brugia malayi Bromodomain containing protein 0.0031 0.0161 0.0161
Schistosoma mansoni hypothetical protein 0.0168 0.1264 0.6814
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.0819 0.3137
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0109 0.2432
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0015 0.0015
Echinococcus multilocularis chromobox protein 1 0.0069 0.0466 0.0451
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0098 0.0879
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0059 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Loa Loa (eye worm) hypothetical protein 0.0256 0.1974 0.1974
Brugia malayi Heterochromatin protein 1 0.0069 0.0466 0.0466
Schistosoma mansoni pyruvate kinase 0.0033 0.0175 0.0875
Brugia malayi chromobox protein homolog 3 0.0039 0.0221 0.0221
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0078 0.1232
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0754 0.2859
Plasmodium falciparum pyruvate kinase 0.0033 0.0175 0.4952
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0059 0.0551
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0208
Echinococcus granulosus dna polymerase eta 0.002 0.0068 0.0053
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0068 0.0289
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0196 0.0622
Echinococcus granulosus pyruvate kinase 0.0017 0.0045 0.0031
Entamoeba histolytica hypothetical protein 0.0025 0.0109 0.1128
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0175 0.052
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0196 0.0605
Giardia lamblia DINP protein human, muc B family 0.002 0.0068 0.0317
Echinococcus multilocularis pyruvate kinase 0.0017 0.0045 0.0031
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0109 0.2681
Trypanosoma brucei trypanothione reductase 0.0049 0.0308 0.3936
Giardia lamblia Pyruvate kinase 0.0033 0.0175 0.1834
Leishmania major pyruvate kinase 0.0033 0.0175 0.1999
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0098 0.0225
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0196 0.0622
Echinococcus multilocularis pyruvate kinase 0.0017 0.0045 0.0031
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0095 0.0799
Schistosoma mansoni hypothetical protein 0.0168 0.1264 0.6814
Brugia malayi beta-lactamase family protein 0.0036 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0256 0.1974 0.1974
Plasmodium vivax ornithine aminotransferase, putative 0.0046 0.028 0.8926
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0221 0.0704
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0047 0.0018
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0245 0.08
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0068 0.0201
Echinococcus multilocularis Aminotransferase class III 0.0046 0.028 0.0265
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0206 0.0191
Trypanosoma brucei protein kinase, putative 0.0105 0.0754 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0068 0.0512
Brugia malayi Pre-SET motif family protein 0.0206 0.1573 0.1573
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0175 0.1999
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0078
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.005 0.0014
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0672 0.0658
Schistosoma mansoni hypothetical protein 0.002 0.0074 0.0319
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0046 0.028 0.075
Echinococcus multilocularis dna polymerase kappa 0.002 0.0068 0.0053
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0109 0.1235
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.005 0.0144
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0047 0.0221
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0196 0.5759
Echinococcus multilocularis geminin 0.0168 0.1264 0.1251
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0047 0.0387
Onchocerca volvulus Alhambra homolog 0.0029 0.0142 0.0337
Schistosoma mansoni lipoxygenase 0.0088 0.0616 0.3281
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0386 0.0372
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0068 0.0673
Trypanosoma brucei unspecified product 0.002 0.0068 0.0673
Mycobacterium tuberculosis Probable reductase 0.0113 0.0819 0.3137
Mycobacterium ulcerans lipase LipD 0.0036 0.0196 0.0605
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0515 0.273
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0284 0.0269
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0142 0.0691
Mycobacterium tuberculosis Conserved protein 0.0036 0.0196 0.0622
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0196 0.0605
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0175 0.2134
Echinococcus granulosus GPCR family 2 0.0032 0.0167 0.0153
Echinococcus multilocularis chromobox protein 1 0.0069 0.0466 0.0451
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0047 0.0221
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0047 0.002
Brugia malayi SET domain containing protein 0.0012 0.0008 0.0008
Brugia malayi hypothetical protein 0.0021 0.0078 0.0078
Echinococcus multilocularis dna polymerase eta 0.002 0.0068 0.0053
Echinococcus granulosus jumonji domain containing protein 0.004 0.0233 0.0218
Leishmania major trypanothione reductase 0.0049 0.0308 0.3831
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0196 0.0622
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0068 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0238 0.1219
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.0819 0.3137
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.1748 0.689
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0047 0.0221
Schistosoma mansoni hypothetical protein 0.0048 0.0293 0.1514
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0109 0.0901
Brugia malayi beta-lactamase 0.0036 0.0196 0.0196
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0047 0.0174
Giardia lamblia Kinase, CMGC MAPK 0.0105 0.0754 1
Chlamydia trachomatis pyruvate kinase 0.0033 0.0175 0.5521
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0196 0.2292
Schistosoma mansoni chromobox protein 0.0069 0.0466 0.2459
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0068 0.0085
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0324 0.2519 1
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0109 0.2432
Loa Loa (eye worm) hypothetical protein 0.0032 0.0167 0.0167
Echinococcus multilocularis mitogen activated protein kinase 3 0.0105 0.0754 0.074
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0284 0.1466
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0147 0.0132
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.1791 0.1779
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0059 0.0519
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0068 0.0068
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.0921 0.3547
Echinococcus multilocularis pyruvate kinase 0.0033 0.0175 0.0161
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0098 0.0879
Schistosoma mansoni bromodomain containing protein 0.0063 0.0415 0.2181
Onchocerca volvulus 0.0036 0.0196 0.0626
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.001 0.001
Plasmodium falciparum phd finger protein, putative 0.0029 0.0142 0.3669
Echinococcus multilocularis pyruvate kinase 0.0033 0.0175 0.0161
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0105 0.0754 1
Schistosoma mansoni hypothetical protein 0.0032 0.0167 0.0831
Schistosoma mansoni zinc finger protein 0.0015 0.0031 0.0087
Echinococcus granulosus chromobox protein 1 0.0069 0.0466 0.0451
Schistosoma mansoni lipoxygenase 0.0126 0.0921 0.4943
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0047 0.0221
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0098 0.0879
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0098 0.0208
Loa Loa (eye worm) hypothetical protein 0.005 0.0308 0.0308
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0167 0.0167
Schistosoma mansoni polycystin 1-related 0.0021 0.0078 0.0342
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0196 0.0181
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0068 0.0068
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0931
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0167 0.0167
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0068 0.0103
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0466 0.1695
Onchocerca volvulus 0.0088 0.0622 0.2871
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0046 0.028 0.0942
Loa Loa (eye worm) hypothetical protein 0.0033 0.0175 0.0175
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0175 0.0175
Onchocerca volvulus 0.0235 0.1803 0.9098
Schistosoma mansoni ap endonuclease 0.0019 0.0059 0.024
Schistosoma mansoni pyruvate kinase 0.0033 0.0175 0.0875
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0196 0.0196
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0233 0.0218
Loa Loa (eye worm) hypothetical protein 0.0036 0.0196 0.0196
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0175 0.0537
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.005
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0175 0.1834
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0175 0.4952
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0078 0.0063
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.0819 0.3137
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0078 0.0063
Loa Loa (eye worm) hypothetical protein 0.003 0.0153 0.0153
Entamoeba histolytica hypothetical protein 0.0074 0.0505 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0931
Loa Loa (eye worm) hypothetical protein 0.0029 0.0142 0.0142
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.0098
Echinococcus multilocularis GPCR, family 2 0.0032 0.0167 0.0153
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.1848 0.1836
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0045 0.003
Onchocerca volvulus 0.003 0.0153 0.0399
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.0819 0.3137
Trichomonas vaginalis esterase, putative 0.0036 0.0196 0.0605
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0308 0.1071
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0324 0.2519 1
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0175 0.0514
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0068 0.0068
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0622 0.0622
Echinococcus granulosus Aminotransferase class III 0.0046 0.028 0.0265
Loa Loa (eye worm) hypothetical protein 0.0088 0.0622 0.0622
Onchocerca volvulus 0.0048 0.0293 0.1132
Echinococcus granulosus pyruvate kinase 0.0033 0.0175 0.0161
Echinococcus granulosus chromobox protein 1 0.0069 0.0466 0.0451
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0068 0.0673
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0009 0.0009
Brugia malayi beta-lactamase family protein 0.0036 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0036 0.0196 0.0196
Onchocerca volvulus 0.0041 0.0238 0.0847
Loa Loa (eye worm) hypothetical protein 0.004 0.0234 0.0234
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.043 0.552
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0196 0.099
Onchocerca volvulus 0.0024 0.0098 0.0107
Schistosoma mansoni hypothetical protein 0.0021 0.0078 0.0342
Toxoplasma gondii exonuclease III APE 0.0019 0.0059 0.019
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.0098
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0047 0.0221
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0206 0.0206
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1803 0.7106
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0046 0.028 0.0942
Mycobacterium ulcerans hypothetical protein 0.0036 0.0196 0.0605
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0167 0.0153
Schistosoma mansoni hypothetical protein 0.0032 0.0167 0.0831
Plasmodium vivax SET domain protein, putative 0.003 0.0147 0.3882
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0754 0.2859
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.043 0.0415
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0142 0.3669
Mycobacterium tuberculosis Conserved protein 0.0036 0.0196 0.0622
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0047 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Schistosoma mansoni rab6-interacting 0.0021 0.0078 0.0342
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0245 0.08
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0726 0.0726
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0754 0.2859
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0098
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0047 0.0221
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0098 0.0208
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0293 0.0293
Leishmania major DNA polymerase eta, putative 0.002 0.0068 0.0512
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.1848 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0047 0.0053
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.0921 0.3547
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0068 0.0085
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0324 0.2519 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0505 0.0491
Mycobacterium tuberculosis Conserved protein 0.0036 0.0196 0.0622
Schistosoma mansoni survival motor neuron protein 0.0048 0.0293 0.1514
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0059 0.0059
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0109 0.0901
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0068 0.0053
Mycobacterium ulcerans hypothetical protein 0.0024 0.0098 0.0208
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0059 0.0044
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0622 0.0608
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0175 0.1999
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.0754 1
Echinococcus granulosus mitogen activated protein kinase 0.0105 0.0754 0.074
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0047 0.0387
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0105 0.0754 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0196 0.0196
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.0921 0.3547
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0105 0.0754 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0095
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0196 0.0622
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0142 0.0127
Leishmania major pyruvate kinase 0.0033 0.0175 0.1999
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0046 0.028 0.075
Echinococcus multilocularis muscleblind protein 0.1251 1 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0804 0.6395 0.6389
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.1848 0.1836
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0196 0.0605
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0068 0.0673
Plasmodium falciparum thioredoxin reductase 0.0049 0.0308 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0068 0.0512
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.024 0.1848 0.1848
Entamoeba histolytica hypothetical protein 0.0074 0.0505 1
Loa Loa (eye worm) hypothetical protein 0.0233 0.1791 0.1791
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0196 0.2422
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0098
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.039 0.039
Loa Loa (eye worm) hypothetical protein 0.0036 0.0196 0.0196
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.043 0.1564
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.043 0.1549
Giardia lamblia PHD finger protein 15 0.0029 0.0142 0.1359
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0068 0.0103
Plasmodium vivax glutathione reductase, putative 0.0049 0.0308 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0196 0.099
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.043 0.2263
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0308 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0196 0.0182
Echinococcus granulosus pyruvate kinase 0.0017 0.0045 0.0031
Loa Loa (eye worm) hypothetical protein 0.0101 0.0726 0.0726
Brugia malayi hypothetical protein 0.0256 0.1974 0.1974
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0196 0.0605
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0196 0.0181
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0175 0.052
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0196 0.0622
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0622 0.0608
Plasmodium falciparum glutathione reductase 0.0017 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0036 0.0196 0.0196
Schistosoma mansoni hypothetical protein 0.0032 0.0167 0.0831
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0059 0.0044
Entamoeba histolytica hypothetical protein 0.0074 0.0505 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0047 0.0047
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0175 0.052
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0059 0.1937
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0196 0.0605
Plasmodium falciparum glutathione reductase 0.0049 0.0308 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0045 0.0163
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0308 0.0308
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0068 0.0673
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0175 0.0175
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.005 0.005
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0095 0.0095
Brugia malayi jmjC domain containing protein 0.0037 0.0206 0.0206
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0147 0.0722
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0068 0.0085
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0078 0.0063
Brugia malayi Bromodomain containing protein 0.0038 0.0215 0.0215
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0142 0.1359
Trypanosoma brucei ISWI complex protein 0.0015 0.0031 0.0169
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0078
Brugia malayi MAP kinase sur-1 0.0105 0.0754 0.0754
Echinococcus granulosus pyruvate kinase 0.0017 0.0045 0.0031
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0175 0.0514
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0175 0.0175
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.1848 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.1848 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0196 0.2292
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0078 0.0078
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0196 0.0196
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0098 0.0208
Schistosoma mansoni hypothetical protein 0.0032 0.0167 0.0831
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.005
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0068 0.0512
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.043 0.5428
Schistosoma mansoni chromobox protein 0.0069 0.0466 0.2459
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0196 0.0605
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0038 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0036 0.0196 0.0196
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0068 0.0512
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.005
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0191 0.0176
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0175 0.0319
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0726 0.0726
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0068 0.0673
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.043 0.0415
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.1848 0.1836
Schistosoma mansoni hypothetical protein 0.0074 0.0505 0.2674
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0138 0.0124
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.043 0.1549
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0726 0.0726
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0059 0.0388
Echinococcus multilocularis pyruvate kinase 0.0017 0.0045 0.0031
Leishmania major DNA polymerase kappa, putative 0.002 0.0068 0.0512
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0098 0.0225
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0059 0.0514
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.005 0.0181
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0284 0.0269
Loa Loa (eye worm) hypothetical protein 0.0069 0.0468 0.0468
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.1848 0.1836
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0089 0.0074
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0147 0.1438
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0931
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0059 0.019
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0089 0.0074
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.0921 0.3399
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0078 0.0063
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0047 0.0221
Echinococcus granulosus muscleblind protein 0.1251 1 1
Echinococcus granulosus peregrin 0.0031 0.0161 0.0146

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.