Detailed information for compound 671666

Basic information

Technical information
  • TDR Targets ID: 671666
  • Name: 2-(4-bromo-2-methylphenoxy)-N-(4-morpholin-4- ylsulfonylphenyl)acetamide
  • MW: 469.349 | Formula: C19H21BrN2O5S
  • H donors: 1 H acceptors: 3 LogP: 2.63 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)S(=O)(=O)N1CCOCC1)COc1ccc(cc1C)Br
  • InChi: 1S/C19H21BrN2O5S/c1-14-12-15(20)2-7-18(14)27-13-19(23)21-16-3-5-17(6-4-16)28(24,25)22-8-10-26-11-9-22/h2-7,12H,8-11,13H2,1H3,(H,21,23)
  • InChiKey: AQCJNXFXXSDHOT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(4-bromo-2-methyl-phenoxy)-N-(4-morpholinosulfonylphenyl)acetamide
  • 2-(4-bromo-2-methylphenoxy)-N-(4-morpholinosulfonylphenyl)acetamide
  • 2-(4-bromo-2-methyl-phenoxy)-N-(4-morpholin-4-ylsulfonylphenyl)ethanamide
  • ARONIS003630
  • AN-329/41328780
  • Oprea1_025743
  • ZINC00675012
  • Oprea1_006127
  • STK061113

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0119 0.1085 0.604
Brugia malayi Bromodomain containing protein 0.0042 0.027 0.0539
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0226 0.2217 0.2792
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0179 0.1724 0.2181
Loa Loa (eye worm) hypothetical protein 0.0108 0.0972 0.1997
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0017 0.0021
Brugia malayi glutathione reductase 0.0052 0.0375 0.0759
Echinococcus multilocularis apoptotic protease activating factor 1 0.009 0.0772 0.0815
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0227 0.079
Brugia malayi follicle stimulating hormone receptor 0.0248 0.245 0.5097
Entamoeba histolytica protein kinase, putative 0.007 0.0565 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0422 0.0847
Treponema pallidum prolyl-tRNA synthetase 0.0024 0.0075 0.0386
Onchocerca volvulus 0.009 0.0772 0.1579
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0158 0.0535
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0013 0.004
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.1651 0.176
Plasmodium falciparum glutathione reductase 0.0052 0.0375 0.0363
Trichomonas vaginalis sugar transporter, putative 0.007 0.0564 0.2034
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0116 0.0103
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0114 0.1036 0.3224
Trichomonas vaginalis conserved hypothetical protein 0.0226 0.2217 0.8136
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.007 0.0565 0.0839
Onchocerca volvulus 0.0032 0.0158 0.0294
Schistosoma mansoni microtubule-associated protein tau 0.0761 0.7907 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0465 0.0588
Trypanosoma cruzi target of rapamycin kinase 3 0.002 0.0033 0.0102
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.0033 0.0102
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0116 0.0157
Loa Loa (eye worm) hypothetical protein 0.0055 0.0405 0.0811
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0032 0.0158 0.0904
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0028 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0169 0.1615 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0562 0.1141
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0227 0.0706
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Echinococcus granulosus Sugar transporter ERD6 protein 0.0032 0.0158 0.0184
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0032 0.0158 0.0904
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0158 0.0491
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.1036 0.131
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0227 0.079
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Schistosoma mansoni zinc finger protein 0.0022 0.005 0.0063
Echinococcus multilocularis synaptic vesicle 2 protein 0.0032 0.0158 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Brugia malayi Probable ClpP-like protease 0.0169 0.1615 0.3353
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0503 0.1567
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0465 0.2823
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0021 0.001
Onchocerca volvulus 0.0032 0.0158 0.0294
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0172 0.1651 0.3419
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0171 0.0216
Echinococcus multilocularis calcium dependent protein kinase 0.0065 0.0509 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0033 0.0044
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0363 0.0724
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0565 0.0593
Schistosoma mansoni lysyl-tRNA synthetase 0.005 0.0356 0.045
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0527 0.19
Echinococcus multilocularis mitogen activated protein kinase 3 0.0114 0.1036 0.1099
Brugia malayi lysyl-tRNA synthetase 0.005 0.0356 0.0719
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0067 0.0527 0.19
Onchocerca volvulus 0.0032 0.0158 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0158 0.0535
Trypanosoma brucei glucose transporter, putative 0.007 0.0564 0.1755
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0375 0.0749
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0375 0.1166
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.037 0.0384
Onchocerca volvulus 0.0032 0.0158 0.0294
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0607 0.1246
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0017 0.0004
Echinococcus multilocularis muscleblind protein 1 0.0167 0.1591 0.1695
Echinococcus multilocularis microtubule associated protein 2 0.0761 0.7907 0.8479
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0067 0.0527 0.19
Echinococcus multilocularis neuropeptide s receptor 0.0512 0.5257 0.5633
Schistosoma mansoni sugar transporter 0.0032 0.0158 0.0199
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0108 0.0971 0.103
Loa Loa (eye worm) hypothetical protein 0.009 0.0772 0.1579
Chlamydia trachomatis proline--tRNA ligase 0.0024 0.0075 0.0386
Schistosoma mansoni glucose transport protein 0.0226 0.2217 0.2803
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Toxoplasma gondii sugar transporter ST3 0.0032 0.0158 0.022
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0375 0.227
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0114 0.1036 0.3224
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0072 0.0588 0.0744
Trypanosoma brucei glucose transporter, putative 0.007 0.0564 0.1755
Echinococcus multilocularis cysteine protease 0.0018 0.0017 0.0005
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0067 0.0527 0.0781
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0227 0.079
Echinococcus granulosus mitogen activated protein kinase 3 0.0114 0.1036 0.1296
Chlamydia trachomatis lysine--tRNA ligase 0.005 0.0356 0.2139
Echinococcus granulosus cathepsin l1 0.0018 0.0017 0.0005
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.0033 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1724 0.6318
Echinococcus granulosus synaptic vesicle 2 protein 0.0032 0.0158 0.0184
Plasmodium falciparum calcium-dependent protein kinase 5 0.007 0.0565 0.0553
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0171 0.024
Brugia malayi hypothetical protein 0.009 0.0772 0.1589
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0167 0.1591 0.3294
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0565 0.0593
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0017 0.0016
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.002 0.0033 0.0287
Plasmodium vivax vivapain-2 0.0018 0.0017 0.0004
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0169 0.1615 0.203
Echinococcus granulosus solute carrier family 22 0.0032 0.0158 0.0184
Echinococcus granulosus solute carrier family 22 0.0032 0.0158 0.0184
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0079 0.0659 0.205
Loa Loa (eye worm) hypothetical protein 0.0068 0.054 0.1093
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0562 0.175
Trypanosoma brucei target of rapamycin kinase 3, putative 0.002 0.0033 0.0102
Loa Loa (eye worm) hypothetical protein 0.0074 0.0607 0.1236
Echinococcus multilocularis serine protein kinase ATM 0.0027 0.0112 0.0106
Echinococcus granulosus apoptotic protease activating factor 1 0.009 0.0772 0.0962
Plasmodium falciparum thioredoxin reductase 0.0052 0.0375 0.0363
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.0033 0.0025
Trypanosoma brucei glucosidase, putative 0.0038 0.0227 0.0706
Schistosoma mansoni sugar transporter 0.0032 0.0158 0.0199
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0043 0.0275 0.1644
Echinococcus granulosus transcription factor Dp 1 0.004 0.025 0.03
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0565 0.0715
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0402 0.1251
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.007 0.0565 0.0553
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0227 0.079
Trypanosoma cruzi metacaspase, putative 0.0067 0.0527 0.1641
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.0971 0.1228
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0017 0.0016
Echinococcus multilocularis mitogen activated protein kinase 0.0114 0.1036 0.1099
Schistosoma mansoni alpha glucosidase 0.0038 0.0227 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Plasmodium vivax SET domain protein, putative 0.0033 0.0171 0.0158
Plasmodium vivax vivapain-2 0.0018 0.0017 0.0004
Leishmania major cathepsin L-like protease 0.0018 0.0017 0.0053
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0169 0.1615 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Brugia malayi Cam kinase protein 1 0.007 0.0565 0.1157
Echinococcus multilocularis Protein lozenge 0.0059 0.0445 0.0464
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0116 0.0103
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0366 0.3703 0.3695
Leishmania major metacaspase, putative 0.0067 0.0527 0.1641
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0079 0.0659 0.205
Trypanosoma cruzi sugar transporter, putative 0.0032 0.0158 0.0491
Brugia malayi Cathepsin L-like precursor 0.0018 0.0017 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0032 0.0158 0.0156
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0044 0.029 0.1022
Trypanosoma brucei glucose transporter, putative 0.007 0.0564 0.1755
Loa Loa (eye worm) hypothetical protein 0.0468 0.4796 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0068 0.054 0.1104
Brugia malayi Cathepsin L-like precursor 0.0018 0.0017 0.0012
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0079 0.0659 0.098
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Plasmodium vivax CDK-related protein kinase 6, putative 0.0958 1 1
Plasmodium vivax lysine--tRNA ligase, putative 0.005 0.0356 0.0343
Leishmania major cathepsin L-like protease 0.007 0.0568 0.1769
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2722 1
Toxoplasma gondii transporter, major facilitator family protein 0.0032 0.0158 0.022
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0465 0.2823
Trichomonas vaginalis sugar transporter, putative 0.007 0.0564 0.2034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0071 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0565 0.2039
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0058 0.0439 0.1225
Trichomonas vaginalis glucose transporter, putative 0.007 0.0564 0.2034
Schistosoma mansoni hypothetical protein 0.0034 0.0185 0.0234
Toxoplasma gondii sugar transporter ST1 0.0032 0.0158 0.022
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.1036 0.3777
Echinococcus multilocularis GPCR, family 2 0.0034 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Schistosoma mansoni peptidase Clp (S14 family) 0.0169 0.1615 0.2043
Loa Loa (eye worm) hypothetical protein 0.0156 0.1478 0.3058
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0112 0.021
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.002 0.0033 0.0287
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.1426 0.4439
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0169 0.1615 0.2433
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0298 0.0927
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0363 0.0376
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0112 0.0348
Echinococcus multilocularis lysyl tRNA synthetase 0.005 0.0356 0.0368
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0375 0.0459
Loa Loa (eye worm) hypothetical protein 0.0078 0.0649 0.1323
Schistosoma mansoni glucose transporter 0.0032 0.0158 0.0199
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0068 0.054 0.1945
Trypanosoma brucei THT1 - hexose transporter, putative 0.007 0.0564 0.1755
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0465 0.0948
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0017 0.0005
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0363 0.0735
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0085 0.0107
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.052 0.0643
Plasmodium vivax glutathione reductase, putative 0.0052 0.0375 0.0363
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0119 0.1085 0.6721
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0013 0.004
Schistosoma mansoni alpha-glucosidase 0.0148 0.1396 0.1766
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0319 0.3213 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0068 0.054 0.0682
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0319 0.3213 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0562 0.175
Onchocerca volvulus 0.0032 0.0158 0.0294
Brugia malayi Cell death protein 3 precursor 0.0156 0.1478 0.3066
Leishmania major glucose transporter, lmgt3 0.007 0.0564 0.1755
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0116 0.0103
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0079 0.0659 0.205
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0298 0.0927
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0132 0.1226 0.7092
Schistosoma mansoni sugar transporter 0.0032 0.0158 0.0199
Trypanosoma brucei glucose transporter, putative 0.007 0.0564 0.1755
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0111 0.0997 0.6172
Mycobacterium ulcerans lysyl-tRNA synthetase 0.005 0.0356 0.2139
Loa Loa (eye worm) hypothetical protein 0.0068 0.054 0.1093
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Leishmania major phosphatidylinositol kinase related protein, putative 0.002 0.0033 0.0103
Trypanosoma brucei metacaspase 5, putative 0.0067 0.0527 0.1641
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Brugia malayi hypothetical protein 0.0468 0.4796 1
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1724 0.6318
Giardia lamblia Lysyl-tRNA synthetase 0.005 0.0356 0.335
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0363 0.0459
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0562 0.175
Echinococcus granulosus muscleblind protein 0.0167 0.1591 0.2
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Echinococcus multilocularis geminin 0.0179 0.1724 0.1838
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Brugia malayi Thioredoxin reductase 0.0052 0.0375 0.0759
Entamoeba histolytica hypothetical protein 0.005 0.0356 0.6178
Giardia lamblia Kinase, CMGC MAPK 0.0114 0.1036 1
Onchocerca volvulus 0.0468 0.4796 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0021 0.0026
Trypanosoma brucei glucose transporter 1E 0.007 0.0564 0.1755
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0562 0.0696
Giardia lamblia Hexose transporter 0.0032 0.0158 0.1416
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0185 0.0218
Toxoplasma gondii hypothetical protein 0.0052 0.0368 0.0539
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.245 0.5091
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0033 0.0021
Trypanosoma cruzi hexose transporter 0.007 0.0564 0.1755
Echinococcus granulosus caspase 3 0.0077 0.0638 0.0792
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0227 0.0706
Trichomonas vaginalis sugar transport protein, putative 0.0032 0.0158 0.0535
Loa Loa (eye worm) hypothetical protein 0.0468 0.4796 1
Brugia malayi Cathepsin L-like precursor 0.0018 0.0017 0.0012
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Schistosoma mansoni lozenge 0.0059 0.0445 0.0563
Leishmania major cathepsin L-like protease 0.0018 0.0017 0.0053
Trypanosoma cruzi hexose transporter, putative 0.007 0.0564 0.1755
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.005 0.0356 0.1265
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0227 0.079
Trypanosoma cruzi metacaspase, putative 0.0067 0.0527 0.1641
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0185 0.0362
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0562 0.059
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0527 0.19
Onchocerca volvulus 0.0033 0.0171 0.0321
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0067 0.0527 0.19
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0226 0.2217 0.2792
Schistosoma mansoni hypothetical protein 0.0179 0.1724 0.2181
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0319 0.3213 1
Echinococcus multilocularis neuropeptide receptor A26 0.0512 0.5257 0.5633
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0465 0.0573
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0227 0.0706
Onchocerca volvulus 0.0032 0.0158 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0298 0.0927
Trypanosoma cruzi glucose transporter, putative 0.0032 0.0158 0.0491
Plasmodium vivax sugar transporter, putative 0.0032 0.0158 0.0145
Onchocerca volvulus 0.0032 0.0158 0.0294
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0158 0.0184
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0363 0.0459
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0226 0.2217 0.2367
Trypanosoma cruzi metacaspase, putative 0.0067 0.0527 0.1641
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.005 0.0356 0.1106
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Echinococcus granulosus solute carrier family 22 0.0032 0.0158 0.0184
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0013 0.0003
Brugia malayi hypothetical protein 0.0032 0.0158 0.0306
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0017 0.0016
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0169 0.1615 0.1605
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.007 0.0565 0.0553
Onchocerca volvulus 0.0032 0.0158 0.0294
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0021 0.0026
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0111 0.0997 0.6172
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.1036 0.3777
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0072 0.0588 0.0744
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0043 0.0275 0.1644
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0185 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Echinococcus multilocularis caspase 8 0.0067 0.0527 0.0553
Onchocerca volvulus Cell death protein 3 homolog 0.0156 0.1478 0.3058
Leishmania major cathepsin L-like protease 0.0018 0.0017 0.0053
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0363 0.0376
Brugia malayi major facilitator superfamily protein 0.0032 0.0158 0.0306
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.005 0.0356 0.0601
Brugia malayi Muscleblind-like protein 0.0167 0.1591 0.3302
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0116 0.0361
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0032 0.0158 0.0491
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0017 0.0021
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0114 0.1036 0.3224
Echinococcus multilocularis caspase 0.0143 0.1344 0.143
Schistosoma mansoni caspase-7 (C14 family) 0.0156 0.1478 0.187
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0013 0.004
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0114 0.1036 0.3224
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.1036 0.3777
Mycobacterium tuberculosis Probable dehydrogenase 0.0119 0.1085 0.6721
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0227 0.079
Brugia malayi Sugar transporter family protein 0.0032 0.0158 0.0306
Trypanosoma brucei metacaspase MCA2 0.0067 0.0527 0.1641
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0227 0.079
Leishmania major lysyl-tRNA synthetase, putative 0.005 0.0356 0.1106
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0562 0.175
Trypanosoma brucei sugar transporter, putative 0.0032 0.0158 0.0491
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0562 0.995
Trypanosoma brucei protein kinase, putative 0.0114 0.1036 0.3224
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0067 0.0527 0.19
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0565 0.0593
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0068 0.054 0.0667
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0171 0.0216
Loa Loa (eye worm) hypothetical protein 0.0047 0.032 0.0635
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.0033 0.0102
Echinococcus granulosus solute carrier family 22 0.0032 0.0158 0.0184
Leishmania major hypothetical protein, conserved 0.0028 0.0116 0.0361
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0013 0.004
Echinococcus granulosus caspase 0.0143 0.1344 0.1687
Loa Loa (eye worm) hypothetical protein 0.0067 0.0527 0.1068
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0226 0.2217 0.2792
Leishmania major cathepsin L-like protease 0.0018 0.0017 0.0053
Schistosoma mansoni hypothetical protein 0.0074 0.0607 0.0768
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0032 0.0158 0.0199
Schistosoma mansoni glucose transport protein 0.0226 0.2217 0.2803
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0114 0.1036 0.1553
Echinococcus multilocularis peptidase Clp (S14 family) 0.0111 0.0997 0.1057
Brugia malayi Pre-SET motif family protein 0.0033 0.0171 0.0333
Brugia malayi Cathepsin L-like precursor 0.0018 0.0017 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.007 0.0565 0.0553
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1724 0.6318
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0017 0.0005
Brugia malayi Sugar transporter family protein 0.0032 0.0158 0.0306
Loa Loa (eye worm) hypothetical protein 0.005 0.0356 0.0708
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0227 0.383
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0032 0.0158 0.0145
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.007 0.0565 0.1147
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0132 0.1226 0.7605
Leishmania major protein kinase, putative 0.007 0.0565 0.1758
Brugia malayi hypothetical protein 0.0032 0.0158 0.0306
Plasmodium falciparum calcium-dependent protein kinase 1 0.007 0.0565 0.0553
Trichomonas vaginalis sugar transporter, putative 0.007 0.0564 0.2034
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0158 0.0535
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Echinococcus granulosus zinc finger protein 0.0022 0.005 0.0047
Giardia lamblia Prolyl-tRNA synthetase 0.0068 0.054 0.5148
Plasmodium falciparum calcium-dependent protein kinase 4 0.007 0.0565 0.0553
Loa Loa (eye worm) hypothetical protein 0.0052 0.037 0.0739
Trypanosoma cruzi metacaspase 5, putative 0.0067 0.0527 0.1641
Brugia malayi MAP kinase sur-1 0.0114 0.1036 0.2141
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.037 0.0468
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Echinococcus granulosus mitogen activated protein kinase 0.0114 0.1036 0.1296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Mycobacterium ulcerans integral membrane transport protein 0.0032 0.0158 0.0904
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0068 0.054 0.0566
Brugia malayi Pre-SET motif family protein 0.023 0.2259 0.4698
Loa Loa (eye worm) major facilitator superfamily transporter 0.0032 0.0158 0.0294
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0013 0.004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.007 0.0565 0.1157
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0017 0.0016
Onchocerca volvulus Putative transporter 0.0032 0.0158 0.0294
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0028 0.0116 0.0207
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0017 0.0016
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0363 0.0444
Mycobacterium ulcerans hypothetical protein 0.0168 0.1608 0.9951
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Loa Loa (eye worm) hypothetical protein 0.0028 0.0116 0.0207
Toxoplasma gondii facilitative glucose transporter GT1 0.0226 0.2217 0.3345
Loa Loa (eye worm) hypothetical protein 0.0169 0.1615 0.3345
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.052 0.0545
Echinococcus granulosus peptidase Clp S14 family 0.0111 0.0997 0.1247
Leishmania major glucose transporter, lmgt1 0.007 0.0564 0.1755
Plasmodium falciparum mitogen-activated protein kinase 2 0.0366 0.3703 0.3695
Echinococcus multilocularis solute carrier family 22 0.0032 0.0158 0.0156
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0024 0.0075 0.0386
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0171 0.0169
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0085 0.0091
Plasmodium falciparum calcium-dependent protein kinase 3 0.007 0.0565 0.0553
Entamoeba histolytica hypothetical protein 0.0027 0.0112 0.1731
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0067 0.0527 0.1078
Brugia malayi Melibiase family protein 0.0072 0.0588 0.1205
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0227 0.0271
Loa Loa (eye worm) hypothetical protein 0.007 0.0565 0.1147
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0185 0.0185
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0226 0.2217 0.2367
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Brugia malayi Major Facilitator Superfamily protein 0.0032 0.0158 0.0306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus granulosus microtubule associated protein 2 0.0761 0.7907 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0465 0.0486
Leishmania major cathepsin L-like protease 0.0018 0.0017 0.0053
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0013 0.004
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0032 0.0158 0.0908
Toxoplasma gondii FATC domain-containing protein 0.0027 0.0112 0.015
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.0033 0.0102
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0013 0.004
Plasmodium vivax metacaspase 1, putative 0.0067 0.0527 0.0515
Echinococcus multilocularis solute carrier family 22 0.0032 0.0158 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0085 0.0078
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Brugia malayi Bromodomain containing protein 0.0083 0.07 0.1438
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.007 0.0565 0.07
Toxoplasma gondii cathepsin CPL 0.0018 0.0017 0.0006
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0119 0.1085 0.6721
Loa Loa (eye worm) hypothetical protein 0.0042 0.027 0.053
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0071 0.0221
Brugia malayi Major Facilitator Superfamily protein 0.0032 0.0158 0.0306
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0017 0.0053
Echinococcus multilocularis zinc finger protein 0.0022 0.005 0.004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0108 0.0972 0.2007
Schistosoma mansoni hypothetical protein 0.0034 0.0185 0.0234
Schistosoma mansoni protein kinase 0.007 0.0565 0.0715
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0375 0.0363
Brugia malayi Cathepsin L-like precursor 0.0018 0.0017 0.0012
Leishmania major mitochondrial DNA polymerase beta 0.0319 0.3213 1
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.1036 0.3777
Leishmania major glucose transporter/membrane transporter D2, putative 0.007 0.0564 0.1755
Leishmania major phosphatidylinositol 3-related kinase, putative 0.002 0.0033 0.0102
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0017 0.0012
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0017 0.0005
Brugia malayi Glycosyl hydrolases family 31 protein 0.0172 0.1651 0.3426
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2722 1
Brugia malayi major facilitator superfamily protein 0.0032 0.0158 0.0306
Echinococcus multilocularis caspase 3 0.0077 0.0638 0.0671
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0158 0.0535
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2722 1
Trypanosoma brucei metacaspase 0.0067 0.0527 0.1641
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0108 0.0972 0.2007
Mycobacterium ulcerans sugar transporter 0.0032 0.0158 0.0904
Loa Loa (eye worm) sugar transporter 0.0226 0.2217 0.4603
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0017 0.0005
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.0033 0.0102
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0068 0.054 0.0682
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0017 0.0004
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0068 0.054 0.1974
Onchocerca volvulus 0.0032 0.0158 0.0294
Onchocerca volvulus Glucosylceramidase homolog 0.0179 0.1724 0.3572
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0143 0.1344 0.1687
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0465 0.1448
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus granulosus GPCR family 2 0.0034 0.0185 0.0218
Toxoplasma gondii hypothetical protein 0.0058 0.0439 0.0647
Loa Loa (eye worm) glutathione reductase 0.0052 0.0375 0.0749
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0063 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0527 0.19
Toxoplasma gondii lysine-tRNA ligase 0.005 0.0356 0.052
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0169 0.1615 0.2433
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0143 0.1344 0.143
Onchocerca volvulus 0.0032 0.0158 0.0294
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0017 0.0053
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0119 0.1085 0.6721
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0227 0.045
Echinococcus multilocularis transcription factor Dp 1 0.004 0.025 0.0255
Loa Loa (eye worm) major facilitator superfamily transporter 0.0032 0.0158 0.0294
Plasmodium vivax calcium-dependent protein kinase, putative 0.007 0.0565 0.0553
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0298 0.0927
Brugia malayi PHD-finger family protein 0.0027 0.0113 0.0212
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0032 0.0158 0.0908
Toxoplasma gondii target of rapamycin (TOR), putative 0.002 0.0033 0.003
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0169 0.1615 1
Schistosoma mansoni caspase-3 (C14 family) 0.0143 0.1344 0.17
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Schistosoma mansoni lysyl-tRNA synthetase 0.005 0.0356 0.045
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0568 0.1769
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0169 0.1615 0.1722
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0227 0.0325
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0168 0.1608 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Toxoplasma gondii sugar transporter ST2 0.0032 0.0158 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2722 1
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0068 0.054 0.9536
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0017 0.0005
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0114 0.1036 0.3224
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0273 0.2722 0.5659
Trypanosoma brucei trypanothione reductase 0.0052 0.0375 0.1166
Echinococcus granulosus calcium dependent protein kinase 0.0065 0.0509 0.0629
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0013 0.004
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.005 0.0356 0.1106
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.007 0.0565 0.07
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0112 0.0366
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0108 0.0971 0.1214
Loa Loa (eye worm) sugar transporter 0.0032 0.0158 0.0294
Schistosoma mansoni protein kinase 0.007 0.0565 0.0715
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0021 0.0008
Toxoplasma gondii protein kinase, putative 0.0638 0.66 1
Schistosoma mansoni hypothetical protein 0.0034 0.0185 0.0234
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0408 0.1271
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0527 0.19
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0067 0.0527 0.19
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.0971 0.1228
Plasmodium falciparum lysine--tRNA ligase 0.005 0.0356 0.0343
Brugia malayi hypothetical protein 0.0032 0.0158 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0564 0.2034
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0375 0.0389
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1827 0.6696
Loa Loa (eye worm) hypothetical protein 0.0167 0.1591 0.3294
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0169 0.1615 1
Brugia malayi hypothetical protein 0.0028 0.0116 0.0219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0067 0.0527 0.0781
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0033 0.0102
Trypanosoma brucei THT1 - hexose transporter, putative 0.007 0.0564 0.1755
Echinococcus multilocularis solute carrier family 22 0.0032 0.0158 0.0156
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0273 0.2722 0.5664
Trypanosoma brucei glucose transporter, putative 0.007 0.0564 0.1755
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.007 0.0565 0.1758
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0363 0.0444
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1827 0.6696
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus granulosus neuropeptide receptor A26 0.0512 0.5257 0.6643
Leishmania major trypanothione reductase 0.0052 0.0375 0.1166
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.0033 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.007 0.0565 0.07
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0562 0.1151
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0033 0.0025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0363 0.0459
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Brugia malayi Major Facilitator Superfamily protein 0.0032 0.0158 0.0306
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0017 0.0005
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0151 0.1426 0.4439
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0013 0.004
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trypanosoma cruzi hexose transporter, putative 0.0038 0.0227 0.0706
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0067 0.0527 0.19
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1724 0.6318
Onchocerca volvulus 0.0261 0.2596 0.5397
Schistosoma mansoni caspase-7 (C14 family) 0.0143 0.1344 0.17
Schistosoma mansoni hypothetical protein 0.0034 0.0185 0.0234
Schistosoma mansoni sugar transporter 0.0032 0.0158 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus granulosus caspase 2 0.0156 0.1478 0.1857
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0033 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0017 0.0016
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.037 0.0453
Echinococcus multilocularis muscleblind protein 0.0167 0.1591 0.1695
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.0033 0.0021
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0465 0.2836
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0169 0.1615 1
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1724 0.6318
Plasmodium falciparum metacaspase 1 0.0067 0.0527 0.0515
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2722 1
Trypanosoma brucei glucose transporter, putative 0.007 0.0564 0.1755
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0227 0.023
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.1036 0.3224
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0058 0.0439 0.0427
Trichomonas vaginalis set domain proteins, putative 0.0261 0.2596 0.9538
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.007 0.0565 0.0839
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0242 0.0246
Leishmania major cathepsin L-like protease 0.007 0.0568 0.1769
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.002 0.0033 0.0102
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0079 0.0659 0.205
Echinococcus multilocularis cysteine protease 0.0018 0.0017 0.0005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.0971 0.1228
Schistosoma mansoni glucose transport protein 0.0226 0.2217 0.2803
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0132 0.1226 0.7605
Plasmodium falciparum metacaspase-like protein 0.0067 0.0527 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0527 0.19
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0027 0.0112 0.0141
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0067 0.0527 0.19
Trypanosoma brucei Metacaspase-4 0.0067 0.0527 0.1641
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0017 0.0016
Leishmania major myo-inositol/proton symporter (MIT) 0.0032 0.0158 0.0491
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0058 0.0439 0.266
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0058 0.0439 0.0427
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Plasmodium falciparum protein kinase 7 0.0638 0.66 0.6596
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0033 0.0041
Plasmodium vivax hexose transporter 0.0226 0.2217 0.2207
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.002 0.0033 0.0102
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0013 0.004
Plasmodium falciparum calcium-dependent protein kinase 2 0.007 0.0565 0.0553
Echinococcus granulosus serine protein kinase ATM 0.0027 0.0112 0.0125
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0033 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.0971 0.1228
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0562 0.0711
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Onchocerca volvulus 0.0032 0.0158 0.0294
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0169 0.1615 0.1605
Leishmania major hypothetical protein, conserved 0.0032 0.0158 0.0491
Loa Loa (eye worm) hypothetical protein 0.0045 0.0298 0.0588
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0227 0.079
Echinococcus granulosus lysosomal alpha glucosidase 0.0172 0.1651 0.2075
Toxoplasma gondii melibiase subfamily protein 0.0108 0.0971 0.1455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0227 0.0439
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.1036 0.3224
Echinococcus granulosus geminin 0.0179 0.1724 0.2168
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0072 0.0588 0.2123
Trypanosoma brucei glucose transporter, putative 0.007 0.0564 0.1755
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0242 0.029
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0013 0.004
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0158 0.0535
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.002 0.0033 0.0102
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0114 0.1036 0.2132
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0067 0.0527 0.0781
Onchocerca volvulus 0.0032 0.0158 0.0294
Onchocerca volvulus 0.0032 0.0158 0.0294
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0013 0.004
Onchocerca volvulus 0.0032 0.0158 0.0294
Schistosoma mansoni alpha-glucosidase 0.0148 0.1396 0.1766
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1724 0.6318
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0116 0.0361
Echinococcus granulosus General substrate transporter 0.0194 0.188 0.2365
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0185 0.0218
Brugia malayi Sugar transporter family protein 0.0226 0.2217 0.4609
Echinococcus granulosus neuropeptide s receptor 0.0512 0.5257 0.6643
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0017 0.0004
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0895 0.9322 1
Plasmodium falciparum hexose transporter 0.0226 0.2217 0.2207
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0067 0.0527 0.0667
Trypanosoma brucei THT1 - hexose transporter, putative 0.007 0.0564 0.1755
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0568 0.1769
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0226 0.2217 0.2367
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.007 0.0565 0.07
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0013 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0568 0.1769
Loa Loa (eye worm) runx1 0.0059 0.0445 0.0895
Trypanosoma cruzi hexose transporter, putative 0.007 0.0564 0.1755
Echinococcus multilocularis caspase 2 0.0156 0.1478 0.1574
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.007 0.0565 0.0839
Trichomonas vaginalis myo-inositol transporter, putative 0.0032 0.0158 0.0535
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Schistosoma mansoni bromodomain containing protein 0.007 0.0562 0.0711
Schistosoma mansoni hypothetical protein 0.009 0.0772 0.0976
Trypanosoma cruzi hexose transporter, putative 0.007 0.0564 0.1755
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0527 0.0515
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0111 0.0997 0.5388
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0564 0.2034
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1724 0.6318
Echinococcus granulosus caspase 8 0.0067 0.0527 0.0652
Echinococcus granulosus lysyl tRNA synthetase 0.005 0.0356 0.0434
Onchocerca volvulus 0.0032 0.0158 0.0294
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0366 0.3703 0.5601
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0169 0.1615 1
Giardia lamblia Sugar-proton symporter 0.0032 0.0158 0.1416
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0108 0.0971 0.103
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0568 0.1769
Echinococcus multilocularis solute carrier family 22 0.0032 0.0158 0.0156
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0017 0.0016
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0068 0.054 0.1104
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0227 0.079
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.1426 0.4439
Plasmodium vivax proline--tRNA ligase, putative 0.0079 0.0659 0.0647
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Mycobacterium ulcerans lysyl-tRNA synthetase 0.005 0.0356 0.2139
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Schistosoma mansoni hypothetical protein 0.0023 0.0063 0.0079
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0013 0.004
Schistosoma mansoni protein kinase 0.007 0.0565 0.0715
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0013 0.0016
Entamoeba histolytica protein kinase, putative 0.007 0.0565 1
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0027 0.0112 0.0348
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0227 0.383
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0067 0.0527 0.19
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0116 0.0361
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0067 0.0527 0.19
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0294
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.037 0.0468
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Giardia lamblia GTOR 0.002 0.0033 0.0195
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0017 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0013 0.004
Trichomonas vaginalis glucose transporter, putative 0.007 0.0564 0.2034
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0226 0.2217 0.2367
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.002 0.0033 0.0102
Leishmania major cathepsin L-like protease 0.007 0.0568 0.1769
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Plasmodium falciparum proline--tRNA ligase 0.0079 0.0659 0.0647
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.002 0.0033 0.0102
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Onchocerca volvulus 0.0032 0.0158 0.0294
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0158 0.0535
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0017 0.0016
Leishmania major glucose transporter, lmgt2 0.007 0.0564 0.1755
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Trypanosoma brucei glucose transporter, putative 0.007 0.0564 0.1755
Echinococcus multilocularis General substrate transporter 0.0194 0.188 0.2005
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0079 0.0659 0.205
Loa Loa (eye worm) hypothetical protein 0.0034 0.0185 0.0351
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0074
Brugia malayi Cathepsin L-like precursor 0.0018 0.0017 0.0012
Schistosoma mansoni hypothetical protein 0.0226 0.2217 0.2803
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.002 0.0033 0.0102
Toxoplasma gondii thioredoxin reductase 0.0052 0.0375 0.055
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2722 1
Trypanosoma brucei glucose transporter 2A 0.007 0.0564 0.1755
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0169 0.1615 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0108 0.0972 0.1997
Onchocerca volvulus 0.01 0.0879 0.1804
Trypanosoma brucei metacaspase MCA3 0.0067 0.0527 0.1641
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0568 0.1769
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0185 0.0362
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.1651 0.176
Mycobacterium tuberculosis Probable oxidoreductase 0.0132 0.1226 0.7605
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0017 0.0016
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0565 0.0593
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0226 0.2217 0.2792
Loa Loa (eye worm) hypothetical protein 0.0072 0.0588 0.1195
Trypanosoma cruzi metacaspase 5, putative 0.0067 0.0527 0.1641
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.007 0.0565 0.1147
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.023 0.2259 0.4692
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0158 0.0535
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0013 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0013 0.004
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0119 0.1085 0.6721
Trypanosoma cruzi metacaspase, putative 0.0067 0.0527 0.1641
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0032 0.0158 0.0904
Mycobacterium tuberculosis Probable reductase 0.0119 0.1085 0.6721
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0527 0.19
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0185 0.0185

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.