Detailed information for compound 75712

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 790.776 | Formula: C37H42N8O12
  • H donors: 8 H acceptors: 12 LogP: -2.71 Rotable bonds: 24
    Rule of 5 violations (Lipinski): 4
  • SMILES: NC(=O)CCC(C(=O)N1CCCC1C(=O)NC(C(=O)NCC(=O)O)CCC(=O)N)NC(=O)C(NC(=O)c1ccc2c(c1)C(=O)C(=O)c1c2cccc1)CCC(=O)N
  • InChi: 1S/C37H42N8O12/c38-27(46)12-9-23(34(54)41-17-30(49)50)43-36(56)26-6-3-15-45(26)37(57)25(11-14-29(40)48)44-35(55)24(10-13-28(39)47)42-33(53)18-7-8-20-19-4-1-2-5-21(19)31(51)32(52)22(20)16-18/h1-2,4-5,7-8,16,23-26H,3,6,9-15,17H2,(H2,38,46)(H2,39,47)(H2,40,48)(H,41,54)(H,42,53)(H,43,56)(H,44,55)(H,49,50)
  • InChiKey: QRXYAJAHHIDAEM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tyrosine protein kinase HCK 0.0795 0.3974 0.3961
Brugia malayi SRC-1 0.1977 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1182 0.5945 0.5935
Treponema pallidum V-type ATP synthase subunit A 0.0051 0.018 0.35
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0795 0.3974 0.3961
Brugia malayi Receptor family ligand binding region containing protein 0.0795 0.3974 0.3959
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Onchocerca volvulus 0.0027 0.0055 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0185 0.0442
Echinococcus granulosus protein kinase 0.0795 0.3974 0.3961
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0008
Onchocerca volvulus 0.0795 0.3974 0.3954
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0303 0.0303
Echinococcus multilocularis kinase suppressor of Ras 1 0.0795 0.3974 0.3961
Echinococcus granulosus tyrosine protein kinase ABL1 0.1977 1 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0795 0.3974 0.3959
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.3959
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0795 0.3974 0.3961
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Entamoeba histolytica tyrosin kinase, putative 0.0795 0.3974 0.3959
Loa Loa (eye worm) protein kinase domain-containing protein 0.0795 0.3974 0.3959
Echinococcus granulosus tyrosine kinase 0.0795 0.3974 0.3961
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0795 0.3974 0.3974
Echinococcus granulosus microtubule associated protein 2 0.1616 0.8158 0.8155
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.1977 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0055 0.0077
Entamoeba histolytica hypothetical protein 0.0027 0.0055 0.003
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Schistosoma mansoni hypothetical protein 0.0139 0.0627 0.0627
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0795 0.3974 0.3959
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0192 0.0192
Echinococcus multilocularis transcription factor Dp 1 0.0045 0.0147 0.0127
Echinococcus multilocularis SH2 motif 0.1182 0.5945 0.5937
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Brugia malayi Cathepsin L-like precursor 0.0052 0.0185 0.0161
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0093 0.0175
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0032 0.0008
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Schistosoma mansoni serine/threonine protein kinase 0.0795 0.3974 0.3974
Brugia malayi ephrin receptor 1 precursor 0.0795 0.3974 0.3959
Loa Loa (eye worm) SH2 domain-containing protein 0.1182 0.5945 0.5935
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0052 0.0185 0.0407
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0067 0.0043
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0185 0.0407
Entamoeba histolytica serine/threonine kinase, putative 0.0795 0.3974 0.3959
Chlamydia trachomatis type III secretion system ATPase 0.0108 0.0469 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.1977 1 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0795 0.3974 1
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0032 0.0008
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0285 0.0265
Brugia malayi Cathepsin L-like precursor 0.0052 0.0185 0.0161
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Onchocerca volvulus Cathepsin L homolog 0.0052 0.0185 0.0153
Schistosoma mansoni tyrosine-protein kinase zap-70 0.1182 0.5945 0.5945
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0032 0.0008
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0055 0.003
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0037 0.0222
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0032 0.0032
Schistosoma mansoni ap endonuclease 0.0021 0.0024 0.0024
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.1182 0.5945 0.5937
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0113 0.0495 0.0475
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0032 0.0008
Echinococcus multilocularis insulin receptor 0.0795 0.3974 0.3961
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0032 0.0012
Brugia malayi Cathepsin L-like precursor 0.0052 0.0185 0.0161
Echinococcus multilocularis muscleblind protein 1 0.0175 0.081 0.0792
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0185 0.0407
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0185 0.0161
Trichomonas vaginalis hypothetical protein 0.0027 0.0055 0.0077
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Brugia malayi Protein kinase domain containing protein 0.1977 1 1
Echinococcus granulosus epidermal growth factor receptor 0.0795 0.3974 0.3961
Loa Loa (eye worm) TK/EPH protein kinase 0.0795 0.3974 0.3959
Mycobacterium leprae PROBABLE ATP SYNTHASE ALPHA CHAIN ATPA 0.0076 0.0308 0.4899
Loa Loa (eye worm) ctsf protein 0.0052 0.0185 0.0162
Loa Loa (eye worm) hypothetical protein 0.0052 0.0185 0.0162
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Echinococcus granulosus tyrosine protein kinase Blk 0.1977 1 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0063 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0032 0.0008
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0795 0.3974 0.3959
Schistosoma mansoni chromobox protein 0.0163 0.075 0.075
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica SH2 domain containing protein 0.1182 0.5945 0.5935
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0027 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0031
Echinococcus multilocularis protein KINase family member (kin 25) 0.0795 0.3974 0.3961
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1977 1 1
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Echinococcus multilocularis survival motor neuron protein 1 0.0246 0.1174 0.1156
Onchocerca volvulus 0.1977 1 1
Schistosoma mansoni SH2A 0.1182 0.5945 0.5945
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0054 0.0192 0.0168
Toxoplasma gondii STE kinase 0.0795 0.3974 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0714 0.0714
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0104 0.0203
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0032 0.0012
Entamoeba histolytica hypothetical protein 0.0084 0.0348 0.0325
Plasmodium vivax tyrosine kinase-like protein, putative 0.0795 0.3974 1
Echinococcus granulosus activated cdc42 kinase 1 0.0795 0.3974 0.3961
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus granulosus vacuolar H ATPase v1 sector subunit A 0.0051 0.018 0.016
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus granulosus integrin linked protein kinase 0.0795 0.3974 0.3961
Schistosoma mansoni hypothetical protein 0.0018 0.001 0.001
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus multilocularis tyrosine protein kinase Abl 0.1977 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0185 0.0407
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0034 0.001
Loa Loa (eye worm) vacuolar ATP synthase subunit B 0.0077 0.0309 0.0286
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) TK/CSK protein kinase 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Schistosoma mansoni tyrosine kinase 0.1977 1 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.1977 1 1
Schistosoma mansoni hypothetical protein 0.1182 0.5945 0.5945
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0057 0.0211 0.0508
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0795 0.3974 1
Onchocerca volvulus 0.005 0.0174 0.0143
Echinococcus multilocularis chromobox protein 1 0.0163 0.075 0.0732
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Brugia malayi hypothetical protein 0.0795 0.3974 0.3959
Trichomonas vaginalis chromobox protein, putative 0.0163 0.075 0.1839
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1182 0.5945 0.5937
Echinococcus granulosus tyrosine protein kinase Src42A 0.1182 0.5945 0.5937
Treponema pallidum V-type ATP synthase subunit A 0.0051 0.018 0.35
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0795 0.3974 0.3959
Brugia malayi SH2 domain containing protein 0.1182 0.5945 0.5935
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0795 0.3974 1
Loa Loa (eye worm) TK/FER protein kinase 0.0795 0.3974 0.3959
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0032 0.0008
Plasmodium vivax vivapain-2 0.0052 0.0185 0.0407
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0055 0.0077
Wolbachia endosymbiont of Brugia malayi ATP synthase F0F1 subunit alpha 0.0076 0.0308 0.6381
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Leishmania major cathepsin L-like protease 0.0052 0.0185 0.0442
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0008
Trichomonas vaginalis TK family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0081
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0156 0.0714 0.0714
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Toxoplasma gondii protein kinase domain-containing protein 0.0795 0.3974 1
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Schistosoma mansoni hypothetical protein 0.0479 0.236 0.236
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica serine/threonine kinase, putative 0.0795 0.3974 0.3959
Trichomonas vaginalis ATP synthase, putative 0.0029 0.0068 0.0111
Echinococcus multilocularis vacuolar H+ ATPase v1 sector subunit A 0.0051 0.018 0.016
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.009 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Trichomonas vaginalis ATP synthase beta subunit, putative 0.0051 0.018 0.0394
Trypanosoma cruzi cruzipain precursor, putative 0.0052 0.0185 0.0442
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0077 0.0313 0.0289
Mycobacterium tuberculosis Probable ATP synthase beta chain AtpD 0.0133 0.0597 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0034 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0795 0.3974 0.3954
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0139 0.0627 0.0608
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0032 0.0012
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0034 0.0061
Brugia malayi Cytochrome P450 family protein 0.0057 0.021 0.0186
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0032 0.0008
Giardia lamblia Protein 21.1 0.0795 0.3974 1
Echinococcus granulosus ATP synthase subunit beta mitochondrial 0.0108 0.0469 0.045
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0067 0.0043
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1182 0.5945 0.5937
Echinococcus granulosus SH2 domain containing adapter protein F 0.1182 0.5945 0.5937
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.1182 0.5945 0.5935
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0032 0.0012
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Brugia malayi vacuolar ATP synthase catalytic subunit A, osteoclast isoform 0.0051 0.018 0.0156
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.1182 0.5945 0.5932
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0795 0.3974 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0037 0.0069
Echinococcus multilocularis cathepsin L cysteine protease 0.0052 0.0185 0.0165
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Echinococcus granulosus retinal guanylyl cyclase 2 0.0795 0.3974 0.3961
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0052 0.0185 0.0407
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0024 0.0037
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0285 0.0265
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0008
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Brugia malayi SH2 domain containing protein 0.1182 0.5945 0.5935
Brugia malayi integrin-linked kinase 0.0795 0.3974 0.3959
Echinococcus granulosus SH2 domain containing protein 7 0.1182 0.5945 0.5937
Loa Loa (eye worm) TK/FER protein kinase 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.1977 1 1
Schistosoma mansoni growth factor receptor-bound protein 0.1182 0.5945 0.5945
Giardia lamblia Vacuolar ATP synthase subunit B 0.0077 0.0309 0.0722
Echinococcus granulosus tyrosine protein kinase 0.0795 0.3974 0.3961
Loa Loa (eye worm) hypothetical protein 0.0072 0.0284 0.0261
Plasmodium vivax heterochromatin protein 1, putative 0.0027 0.0055 0.0077
Loa Loa (eye worm) runx1 0.0065 0.025 0.0227
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0211 0.0211
Brugia malayi protein-tyrosine kinase 0.1977 1 1
Entamoeba histolytica serine/threonine kinase, putative 0.0795 0.3974 0.3959
Leishmania major ATPase beta subunit, putative 0.0108 0.0469 0.1159
Giardia lamblia Cathepsin B precursor 0.0057 0.0211 0.0473
Schistosoma mansoni ATP synthase alpha subunit mitochondrial 0.0076 0.0308 0.0308
Leishmania major vacuolar ATP synthase subunit b, putative 0.0077 0.0309 0.0756
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.005 0.0579
Wolbachia endosymbiont of Brugia malayi transcription termination factor Rho 0.0022 0.003 0.0138
Brugia malayi cathepsin L-like precursor 0.0036 0.0104 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0795 0.3974 0.3974
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.005 0.0102
Schistosoma mansoni tensin 0.1182 0.5945 0.5945
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Brugia malayi Melibiase family protein 0.0075 0.0303 0.0279
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.0133 0.0113
Onchocerca volvulus ATP synthase subunit alpha, mitochondrial homolog 0.0076 0.0308 0.0277
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0185 0.0442
Trypanosoma brucei unspecified product 0.0038 0.0112 0.0259
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Echinococcus multilocularis ephrin type A receptor 4 A 0.0795 0.3974 0.3961
Brugia malayi hypothetical protein 0.0519 0.2563 0.2545
Trypanosoma cruzi cysteine protease, putative 0.0029 0.0067 0.0144
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0795 0.3974 0.3961
Onchocerca volvulus 0.1182 0.5945 0.5932
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0031 0.0076 0.0076
Entamoeba histolytica SH2-protein kinase domain containing protein 0.1182 0.5945 0.5935
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus granulosus ATPase H transporting lysosomal accessory 0.0249 0.1186 0.1169
Trichomonas vaginalis conserved hypothetical protein 0.0795 0.3974 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0495 0.0495
Loa Loa (eye worm) TK/ROR protein kinase 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Leishmania major ATPase alpha subunit 0.0047 0.0159 0.0375
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Brugia malayi hypothetical protein 0.1182 0.5945 0.5935
Echinococcus granulosus activin receptor type 0.0795 0.3974 0.3961
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0077 0.0313 0.0764
Echinococcus multilocularis N chimaerin 0.1182 0.5945 0.5937
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0313 0.0764
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Echinococcus granulosus SHC transforming protein 3 0.1182 0.5945 0.5937
Onchocerca volvulus 0.0795 0.3974 0.3954
Schistosoma mansoni hypothetical protein 0.0084 0.0348 0.0348
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0055 0.0077
Loa Loa (eye worm) TK/FER protein kinase 0.0795 0.3974 0.3959
Brugia malayi STAT protein, DNA binding domain containing protein 0.1182 0.5945 0.5935
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Plasmodium falciparum V-type proton ATPase subunit B 0.0077 0.0309 0.0722
Leishmania major cysteine peptidase A (CPA) 0.0052 0.0185 0.0442
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica hypothetical protein, conserved 0.0795 0.3974 0.3959
Echinococcus granulosus raf serine:threonine protein kinase 0.0795 0.3974 0.3961
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Leishmania major cathepsin L-like protease 0.0052 0.0185 0.0442
Loa Loa (eye worm) hypothetical protein 0.0175 0.081 0.0788
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0795 0.3974 0.3961
Loa Loa (eye worm) TK/ALK protein kinase 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) ATP synthase subunit beta 0.0079 0.032 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.1182 0.5945 0.5937
Brugia malayi C-terminal src kinase protein 1 0.0795 0.3974 0.3959
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0054 0.0192 0.0168
Loa Loa (eye worm) hypothetical protein 0.0246 0.1174 0.1153
Echinococcus granulosus retinal guanylyl cyclase 2 0.0795 0.3974 0.3961
Leishmania major cathepsin L-like protease 0.0052 0.0185 0.0442
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0032 0.0012
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.1977 1 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Loa Loa (eye worm) TK/DDR protein kinase 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0795 0.3974 0.3961
Onchocerca volvulus 0.1182 0.5945 0.5932
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0795 0.3974 0.3959
Echinococcus granulosus hypothetical protein 0.1182 0.5945 0.5937
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0032 0.0008
Brugia malayi Cathepsin L-like precursor 0.0036 0.0104 0.008
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0029 0.0067 0.0144
Loa Loa (eye worm) TK protein kinase 0.0795 0.3974 0.3959
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0024 0.0037
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1977 1 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0795 0.3974 0.3959
Brugia malayi hypothetical protein 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.1977 1 1
Onchocerca volvulus 0.0052 0.0185 0.0153
Loa Loa (eye worm) hypothetical protein 0.0083 0.0341 0.0318
Echinococcus multilocularis raf serine:threonine protein kinase 0.0795 0.3974 0.3961
Echinococcus multilocularis SHC transforming protein 3 0.1182 0.5945 0.5937
Loa Loa (eye worm) TK protein kinase 0.0795 0.3974 0.3959
Schistosoma mansoni survival motor neuron protein 0.005 0.0174 0.0174
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Loa Loa (eye worm) TK/EGFR protein kinase 0.0795 0.3974 0.3959
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0795 0.3974 0.3959
Echinococcus granulosus natriuretic peptide receptor 1 0.0795 0.3974 0.3961
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Echinococcus multilocularis dna polymerase kappa 0.0045 0.0149 0.013
Schistosoma mansoni tensin 0.1182 0.5945 0.5945
Plasmodium vivax SET domain protein, putative 0.0036 0.01 0.0193
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Leishmania major cytochrome p450-like protein 0.0023 0.0034 0.0061
Onchocerca volvulus 0.0795 0.3974 0.3954
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0052 0.0185 0.0165
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0795 0.3974 1
Echinococcus multilocularis tensin 0.1182 0.5945 0.5937
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Brugia malayi SH2 domain containing protein 0.1182 0.5945 0.5935
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0032 0.0008
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0077 0.0313 0.0289
Echinococcus granulosus dna polymerase kappa 0.0045 0.0149 0.013
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0795 0.3974 0.3961
Echinococcus multilocularis tyrosine protein kinase shark 0.1977 1 1
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0027 0.0055 0.0055
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0795 0.3974 0.3961
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0795 0.3974 0.3961
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0032 0.0032
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Echinococcus granulosus muscleblind protein 0.0175 0.081 0.0792
Echinococcus granulosus growth factor receptor bound protein 2 0.1182 0.5945 0.5937
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0795 0.3974 0.3961
Schistosoma mansoni zinc finger protein 0.0025 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0091 0.0385 0.0362
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.005 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0067 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0385 0.0913
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0032 0.0012
Echinococcus multilocularis FL cytokine receptor 0.0795 0.3974 0.3961
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0031 0.0076 0.0056
Brugia malayi Tensin 0.1182 0.5945 0.5935
Echinococcus granulosus tyrosine protein kinase Fyn 0.1977 1 1
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Leishmania major ATPase alpha subunit 0.0047 0.0159 0.0375
Brugia malayi SH2 domain containing protein 0.1977 1 1
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0795 0.3974 0.3959
Brugia malayi ecdysteroid receptor 0.0022 0.0032 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Trypanosoma cruzi cysteine peptidase, putative 0.0029 0.0067 0.0144
Brugia malayi RhoGAP domain containing protein 0.1182 0.5945 0.5935
Echinococcus multilocularis SH2 motif 0.1182 0.5945 0.5937
Brugia malayi Variant SH3 domain containing protein 0.1182 0.5945 0.5935
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.1977 1 1
Loa Loa (eye worm) SRC-1 0.1977 1 1
Echinococcus multilocularis zinc finger protein 0.0025 0.0045 0.0025
Trypanosoma brucei protein kinase, putative 0.0795 0.3974 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0034 0.0061
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0032 0.0032
Loa Loa (eye worm) sex muscle abnormal protein 5 0.1182 0.5945 0.5935
Trichomonas vaginalis conserved hypothetical protein 0.0795 0.3974 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1977 1 1
Brugia malayi Cathepsin L-like precursor 0.0052 0.0185 0.0161
Leishmania major protein kinase, putative 0.0795 0.3974 1
Mycobacterium tuberculosis Probable transcription termination factor Rho homolog 0.0022 0.003 0.0107
Onchocerca volvulus 0.0034 0.009 0.0058
Trichomonas vaginalis protein tyrosine kinase, putative 0.0795 0.3974 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1182 0.5945 0.5935
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.002 0.002
Echinococcus granulosus cysteine protease 0.0029 0.0067 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0192 0.0192
Mycobacterium ulcerans F0F1 ATP synthase subunit alpha 0.0076 0.0308 0.6381
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0237 0.0237
Leishmania major cathepsin L-like protease 0.0052 0.0185 0.0442
Echinococcus granulosus dnaJ subfamily B 0.0479 0.236 0.2345
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0093 0.0175
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1182 0.5945 0.5937
Leishmania major cathepsin L-like protease 0.0052 0.0185 0.0442
Schistosoma mansoni bromodomain containing protein 0.0076 0.0306 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0055 0.0077
Brugia malayi SH2 domain containing protein 0.1182 0.5945 0.5935
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0795 0.3974 0.3959
Schistosoma mansoni microtubule-associated protein tau 0.1616 0.8158 0.8158
Plasmodium falciparum cysteine proteinase falcipain 3 0.0052 0.0185 0.0407
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Brugia malayi Variant SH3 domain containing protein 0.1182 0.5945 0.5935
Echinococcus multilocularis tyrosine protein kinase Srms 0.1977 1 1
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Trypanosoma brucei Flagellum attachment zone protein 20 0.0795 0.3974 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0055 0.0077
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Plasmodium vivax vivapain-2 0.0052 0.0185 0.0407
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0032 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.01 0.0253
Echinococcus multilocularis tyrosine protein kinase csk 0.0795 0.3974 0.3961
Leishmania major hypothetical protein, conserved 0.0795 0.3974 1
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.009 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0067 0.0107
Brugia malayi Bromodomain containing protein 0.0045 0.0147 0.0123
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0081
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0113 0.0495 0.0475
Leishmania major vacuolar ATP synthase catalytic subunit A, putative 0.0051 0.018 0.0429
Loa Loa (eye worm) TK/FER protein kinase 0.0795 0.3974 0.3959
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1977 1 1
Plasmodium falciparum tyrosine kinase-like protein 0.0795 0.3974 1
Schistosoma mansoni hypothetical protein 0.005 0.0174 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0075 0.013
Brugia malayi SH2 domain containing protein 0.1182 0.5945 0.5935
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Mycobacterium ulcerans DNA polymerase IV 0.0045 0.0149 0.2816
Loa Loa (eye worm) CHromoDomain protein family member 0.0031 0.0076 0.0052
Echinococcus granulosus tyrosine kinase 0.1977 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Schistosoma mansoni ATP synthase alpha subunit vacuolar 0.0051 0.018 0.018
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1182 0.5945 0.5937
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0795 0.3974 0.3974
Brugia malayi PHD-finger family protein 0.0031 0.0077 0.0053
Onchocerca volvulus 0.0052 0.0185 0.0153
Echinococcus granulosus transcription factor Dp 1 0.0045 0.0147 0.0127
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Onchocerca volvulus 0.0795 0.3974 0.3954
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0032 0.0008
Brugia malayi Guanylyl cyclase protein 23 0.0795 0.3974 0.3959
Schistosoma mansoni tensin 0.1182 0.5945 0.5945
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0795 0.3974 0.3959
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0012 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0249 0.0568
Loa Loa (eye worm) vacuolar H ATPase family member 0.0051 0.018 0.0156
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Brugia malayi Protein cec-1. 0.0027 0.0055 0.003
Entamoeba histolytica hypothetical protein 0.0084 0.0348 0.0325
Entamoeba histolytica serine/threonine kinase, putative 0.0795 0.3974 0.3959
Brugia malayi Cathepsin L-like precursor 0.0036 0.0104 0.008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0081
Trypanosoma brucei V-type ATPase, A subunit, putative 0.0051 0.018 0.0429
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Echinococcus multilocularis chromobox protein 2 0.0027 0.0055 0.0034
Plasmodium falciparum protein kinase, putative 0.0795 0.3974 1
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Echinococcus multilocularis Chromobox protein 3 0.0027 0.0055 0.0034
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0495 0.0495
Echinococcus granulosus Chromobox protein 3 0.0027 0.0055 0.0034
Echinococcus multilocularis NCK adaptor protein 0.1182 0.5945 0.5937
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0031
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0024 0.0037
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Echinococcus granulosus tyrosine protein kinase HCK 0.0795 0.3974 0.3961
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trypanosoma cruzi V-type ATPase, A subunit, putative 0.0051 0.018 0.0429
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0027 0.0055 0.0137
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0795 0.3974 1
Onchocerca volvulus 0.0052 0.0185 0.0153
Echinococcus granulosus tyrosine protein kinase csk 0.0795 0.3974 0.3961
Entamoeba histolytica cysteine surface protein, putative 0.0795 0.3974 0.3959
Schistosoma mansoni growth factor receptor-bound protein 0.1182 0.5945 0.5945
Brugia malayi bone morphogenetic protein type 1 receptor 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Giardia lamblia Vacuolar ATP synthase catalytic subunit A 0.0051 0.018 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Brugia malayi CXXC zinc finger family protein 0.0034 0.009 0.0066
Onchocerca volvulus 0.1182 0.5945 0.5932
Schistosoma mansoni coup transcription factor 0.0022 0.0032 0.0032
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0052 0.0185 0.0162
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0057 0.0211 0.0508
Echinococcus granulosus cpg binding protein 0.0038 0.0111 0.0091
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Onchocerca volvulus 0.1977 1 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0844 0.4223 0.4211
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.3959
Schistosoma mansoni suppressor of cytokine signaling 0.1182 0.5945 0.5945
Echinococcus granulosus insulin receptor 0.0795 0.3974 0.3961
Echinococcus granulosus NCK adaptor protein 0.1182 0.5945 0.5937
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Onchocerca volvulus 0.1182 0.5945 0.5932
Trypanosoma brucei ATP synthase F1, alpha subunit 0.0047 0.0159 0.0375
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Trypanosoma cruzi cysteine proteinase, putative 0.0029 0.0067 0.0144
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0093 0.0175
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1182 0.5945 0.5937
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Schistosoma mansoni tyrosine kinase 0.1977 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0385 0.0913
Brugia malayi Variant SH3 domain containing protein 0.1182 0.5945 0.5935
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0034 0.001
Loa Loa (eye worm) hypothetical protein 0.0092 0.0386 0.0363
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.1182 0.5945 0.5945
Entamoeba histolytica V-type ATPase, B subunit, putative 0.0077 0.0309 0.0286
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.01 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0032 0.0008
Plasmodium vivax vacuolar ATP synthase catalytic subunit A, putative 0.0051 0.018 0.0394
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Entamoeba histolytica V-type ATPase, A subunit, putative 0.0051 0.018 0.0156
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0185 0.0407
Trichomonas vaginalis ATP synthase alpha subunit mitochondrial, putative 0.0077 0.0309 0.0722
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Toxoplasma gondii melibiase subfamily protein 0.0113 0.0495 0.1245
Loa Loa (eye worm) hypothetical protein 0.0519 0.2563 0.2545
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0031
Entamoeba histolytica vacuolar ATP synthase subunit B, putative 0.0029 0.0068 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0032 0.0012
Brugia malayi Sex muscle abnormal protein 5 0.1182 0.5945 0.5935
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0054 0.0192 0.0172
Trypanosoma cruzi ATP synthase subunit beta, mitochondrial, putative 0.0108 0.0469 0.1159
Trichomonas vaginalis CAMK family protein kinase 0.0795 0.3974 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Trypanosoma brucei Pseudokinase, putative 0.0795 0.3974 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0185 0.0407
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.396
Echinococcus multilocularis cathepsin b 0.0156 0.0714 0.0695
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus multilocularis ATPase, H+ transporting, lysosomal accessory 0.0249 0.1186 0.1169
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0192 0.0192
Trichomonas vaginalis DNA polymerase eta, putative 0.0045 0.0149 0.0317
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0032 0.0012
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Echinococcus granulosus tensin 0.1182 0.5945 0.5937
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0056 0.0202 0.0202
Schistosoma mansoni hypothetical protein 0.0027 0.0055 0.0055
Brugia malayi Associated with TFs and helicases family protein 0.0027 0.0055 0.003
Schistosoma mansoni hypothetical protein 0.0795 0.3974 0.3974
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0313 0.0764
Schistosoma mansoni tyrosine kinase 0.1977 1 1
Trypanosoma cruzi protein kinase, putative 0.0795 0.3974 1
Echinococcus granulosus SH2 motif 0.1182 0.5945 0.5937
Onchocerca volvulus Cathepsin F homolog 0.0052 0.0185 0.0153
Schistosoma mansoni ap endonuclease 0.0021 0.0024 0.0024
Echinococcus granulosus tyrosine protein kinase Src64B 0.1977 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Toxoplasma gondii vacuolar ATP synthase subunit b, putative 0.0077 0.0309 0.0779
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Echinococcus granulosus vacuolar ATP synthase subunit b 0.0077 0.0309 0.029
Loa Loa (eye worm) SH2 domain-containing protein 0.1182 0.5945 0.5935
Trichomonas vaginalis AGC family protein kinase 0.0795 0.3974 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0795 0.3974 1
Loa Loa (eye worm) TK protein kinase 0.0795 0.3974 0.3959
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Schistosoma mansoni zinc finger protein 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0008
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0795 0.3974 0.396
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0055 0.0077
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0056 0.0202 0.0202
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0077 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0032 0.0032
Onchocerca volvulus 0.0062 0.0237 0.0205
Loa Loa (eye worm) hypothetical protein 0.0052 0.0183 0.0159
Trypanosoma brucei ATP synthase F1, alpha subunit 0.0047 0.0159 0.0375
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0112 0.0259
Giardia lamblia Kinase, NEK 0.0795 0.3974 1
Loa Loa (eye worm) hypothetical protein 0.0156 0.0714 0.0692
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1977 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0185 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0012 0.0005
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.0133 0.0113
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.3959
Brugia malayi Tyrosine-protein kinase PR2 0.0795 0.3974 0.3959
Trypanosoma cruzi cysteine proteinase, putative 0.0029 0.0067 0.0144
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1182 0.5945 0.5935
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0077 0.0313 0.0289
Echinococcus granulosus tyrosine protein kinase Fyn 0.1977 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Trypanosoma brucei ATP synthase subunit beta, mitochondrial 0.0108 0.0469 0.1159
Onchocerca volvulus 0.1977 1 1
Treponema pallidum V-type ATP synthase subunit B 0.0077 0.0309 0.6412
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0032 0.0008
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Echinococcus multilocularis tyrosine protein kinase pr2 0.0795 0.3974 0.3961
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0249 0.0568
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.396
Echinococcus multilocularis protein kinase 0.0795 0.3974 0.3961
Schistosoma mansoni ATP synthase beta subunit 0.0108 0.0469 0.0469
Trypanosoma brucei cysteine peptidase C (CPC) 0.0057 0.0211 0.0508
Echinococcus multilocularis protein kinase 0.0795 0.3974 0.3961
Echinococcus multilocularis c src tyrosine kinase 0.1977 1 1
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus multilocularis transfer RNA-Thr 0.0795 0.3974 0.3961
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0031
Echinococcus multilocularis cysteine protease 0.0052 0.0185 0.0165
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.3959
Toxoplasma gondii ATP synthase beta subunit ATP-B 0.0108 0.0469 0.118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Loa Loa (eye worm) TK protein kinase 0.0795 0.3974 0.3959
Brugia malayi Bromodomain containing protein 0.009 0.0376 0.0353
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0052 0.0185 0.0407
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0795 0.3974 0.3961
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.005 0.0126
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0795 0.3974 0.3961
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0042 0.0018
Echinococcus multilocularis signal transduction protein lnk realted 0.1182 0.5945 0.5937
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0139 0.0627 0.0608
Echinococcus granulosus protein tyrosine kinase 0.0795 0.3974 0.3961
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Echinococcus multilocularis 0.1182 0.5945 0.5937
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0795 0.3974 0.3961
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Schistosoma mansoni adapter molecule crk 0.1182 0.5945 0.5945
Echinococcus multilocularis Protein lozenge 0.0065 0.025 0.023
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0795 0.3974 0.3961
Entamoeba histolytica protein kinase, putative 0.1182 0.5945 0.5935
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1977 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0034 0.0061
Brugia malayi steroid hormone receptor 0.0022 0.0032 0.0008
Echinococcus granulosus signal transduction protein lnk realted 0.1182 0.5945 0.5937
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0077 0.0313 0.0293
Brugia malayi Tyrosine-protein kinase abl-1 0.1977 1 1
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Mycobacterium ulcerans F0F1 ATP synthase subunit beta 0.0108 0.0469 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.0795 0.3974 0.3961
Brugia malayi SH2 domain containing protein 0.1977 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Echinococcus multilocularis natriuretic peptide receptor 1 0.0795 0.3974 0.3961
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus multilocularis epidermal growth factor receptor 0.0795 0.3974 0.3961
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0795 0.3974 0.3959
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Plasmodium vivax ATP synthase alpha chain, putative 0.0076 0.0308 0.0719
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Echinococcus multilocularis tyrosine protein kinase csk 0.0795 0.3974 0.3961
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0036 0.0104 0.0239
Entamoeba histolytica serine/threonine kinase, putative 0.0795 0.3974 0.3959
Echinococcus multilocularis cathepsin b 0.0156 0.0714 0.0695
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Leishmania major cathepsin L-like protease 0.0052 0.0185 0.0442
Leishmania major DNA polymerase kappa, putative 0.0023 0.0037 0.0069
Onchocerca volvulus 0.0052 0.0185 0.0153
Schistosoma mansoni chromobox protein 0.0163 0.075 0.075
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.3959
Entamoeba histolytica tyrosin kinase, putative 0.0795 0.3974 0.3959
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0027 0.0055 0.003
Echinococcus multilocularis cysteine protease 0.0052 0.0185 0.0165
Schistosoma mansoni tensin-related 0.1182 0.5945 0.5945
Echinococcus granulosus histone lysine methyltransferase setb 0.0056 0.0202 0.0182
Schistosoma mansoni nck2/grb4 0.1182 0.5945 0.5945
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Chlamydia trachomatis type III secretion system ATP synthase 0.0051 0.018 0.3409
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0055 0.0077
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.396
Leishmania major protein kinase, putative 0.0795 0.3974 1
Echinococcus multilocularis SH2 domain containing adapter protein F 0.1182 0.5945 0.5937
Schistosoma mansoni transcription factor LCR-F1 0.0084 0.0348 0.0348
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.005 0.0102
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.021 0.0186
Echinococcus granulosus tyrosine protein kinase Fyn 0.1977 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0185 0.0407
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0052 0.0185 0.0165
Echinococcus granulosus retinal guanylyl cyclase 2 0.0795 0.3974 0.3961
Loa Loa (eye worm) TK protein kinase 0.0795 0.3974 0.3959
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0029 0.0067 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0093 0.0175
Entamoeba histolytica hypothetical protein 0.0084 0.0348 0.0325
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0244 0.1165 0.1144
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0156 0.0714 0.1777
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0031
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.005 0.0447
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0795 0.3974 0.3961
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0029 0.0067 0.0067
Onchocerca volvulus 0.0795 0.3974 0.3954
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus granulosus Chromo domain 0.0027 0.0055 0.0034
Leishmania major cathepsin L-like protease 0.0052 0.0185 0.0442
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0795 0.3974 0.3959
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.1182 0.5945 0.5937
Echinococcus multilocularis dnaJ subfamily B 0.0479 0.236 0.2345
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0032 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0795 0.3974 0.3959
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0104 0.0104
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Brugia malayi Protein kinase domain containing protein 0.1977 1 1
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Onchocerca volvulus 0.0072 0.0284 0.0253
Entamoeba histolytica hypothetical protein 0.0027 0.0055 0.003
Loa Loa (eye worm) cysteine protease 0.0052 0.0185 0.0162
Giardia lamblia Cathepsin B precursor 0.0057 0.0211 0.0473
Trichomonas vaginalis conserved hypothetical protein 0.0795 0.3974 1
Plasmodium vivax vivapain-3 0.0029 0.0067 0.0107
Echinococcus granulosus tyrosine protein kinase csk 0.0795 0.3974 0.3961
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Toxoplasma gondii histone lysine methyltransferase SET1 0.0068 0.0264 0.0664
Loa Loa (eye worm) hypothetical protein 0.0519 0.2563 0.2545
Echinococcus granulosus SH2 motif 0.1182 0.5945 0.5937
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0795 0.3974 0.3959
Echinococcus granulosus tyrosine protein kinase Srms 0.1977 1 1
Brugia malayi Pre-SET motif family protein 0.0244 0.1165 0.1143
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.1182 0.5945 0.5945
Plasmodium falciparum ATP synthase subunit beta, mitochondrial 0.0108 0.0469 0.1126
Echinococcus multilocularis activated cdc42 kinase 1 0.0795 0.3974 0.3961
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1182 0.5945 0.5937
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Brugia malayi ATP synthase alpha chain, mitochondrial precursor, putative 0.0076 0.0308 0.0285
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0174 0.0151
Loa Loa (eye worm) hypothetical protein 0.0034 0.0093 0.007
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0795 0.3974 1
Echinococcus granulosus expressed conserved protein 0.1182 0.5945 0.5937
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0075 0.0303 0.0705
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Brugia malayi SET domain containing protein 0.0029 0.0065 0.0041
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Loa Loa (eye worm) serine/threonine protein kinase 0.0795 0.3974 0.3959
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0029 0.0067 0.0067
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Onchocerca volvulus 0.0278 0.1336 0.1308
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Onchocerca volvulus 0.0519 0.2563 0.2539
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0008
Plasmodium vivax protein kinase, putative 0.0795 0.3974 1
Loa Loa (eye worm) TK/FER protein kinase 0.0795 0.3974 0.3959
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0032 0.0012
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0032 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0027 0.0055 0.0137
Entamoeba histolytica cysteine protease, putative 0.0052 0.0185 0.0161
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0795 0.3974 0.3961
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Entamoeba histolytica cysteine proteinase 1, putative 0.0029 0.0067 0.0043
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Echinococcus multilocularis integrin linked protein kinase 0.0795 0.3974 0.3961
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Echinococcus granulosus kinase suppressor of Ras 1 0.0795 0.3974 0.3961
Echinococcus granulosus tyrosine protein kinase pr2 0.0795 0.3974 0.3961
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) RGC/RGC protein kinase 0.0795 0.3974 0.3959
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0032 0.0012
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0795 0.3974 0.3961
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.005 0.0579
Echinococcus granulosus tyrosine protein kinase Fps85D 0.1977 1 1
Treponema pallidum V-type ATP synthase subunit B 0.0077 0.0309 0.6412
Leishmania major ATPase beta subunit, putative 0.0108 0.0469 0.1159
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0075 0.013
Schistosoma mansoni chromobox protein 0.0027 0.0055 0.0055
Brugia malayi hypothetical protein 0.0246 0.1174 0.1152
Echinococcus granulosus L aminoadipate semialdehyde 0.0092 0.0386 0.0367
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.002 0.002
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.396
Schistosoma mansoni ATP synthase subunit beta vacuolar 0.0077 0.0309 0.0309
Plasmodium falciparum protein kinase, putative 0.0795 0.3974 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0495 0.0495
Entamoeba histolytica cysteine proteinase 2 0.0029 0.0067 0.0043
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0795 0.3974 0.3959
Schistosoma mansoni vav2 0.1182 0.5945 0.5945
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0055 0.0077
Toxoplasma gondii vacuolar ATP synthase subunit A, putative 0.0051 0.018 0.0453
Echinococcus multilocularis tyrosine protein kinase csk 0.0795 0.3974 0.3961
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Schistosoma mansoni thyroid hormone receptor 0.0161 0.0741 0.0741
Loa Loa (eye worm) TK/FAK protein kinase 0.0795 0.3974 0.3959
Plasmodium falciparum cysteine proteinase falcipain 1 0.0029 0.0067 0.0107
Chlamydia trachomatis V-type ATP synthase subunit B 0.0077 0.0309 0.6361
Brugia malayi Furin-like cysteine rich region family protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Trypanosoma cruzi Vacuolar proton pump subunit B, putative 0.0077 0.0309 0.0756
Echinococcus multilocularis cpg binding protein 0.0038 0.0111 0.0091
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Entamoeba histolytica tyrosin kinase, putative 0.0795 0.3974 0.3959
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus granulosus cathepsin b 0.0156 0.0714 0.0695
Brugia malayi Immunoglobulin I-set domain containing protein 0.0795 0.3974 0.3959
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0029 0.0067 0.0144
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0055 0.0077
Echinococcus multilocularis suppressor of cytokine signaling 6 0.1182 0.5945 0.5937
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0092 0.0386 0.0363
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0185 0.0442
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1182 0.5945 0.5937
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0037 0.0069
Entamoeba histolytica ankyrin repeat protein 0.0795 0.3974 0.3959
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0495 0.0495
Echinococcus granulosus suppressor of cytokine signaling 6 0.1182 0.5945 0.5937
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0795 0.3974 0.3959
Trichomonas vaginalis conserved hypothetical protein 0.0795 0.3974 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0795 0.3974 0.3961
Loa Loa (eye worm) RGC/RGC protein kinase 0.0795 0.3974 0.3959
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.01 0.008
Brugia malayi Muscleblind-like protein 0.0175 0.081 0.0788
Loa Loa (eye worm) TK/FER protein kinase 0.0795 0.3974 0.3959
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0012 0.0005
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1977 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Brugia malayi Protein kinase domain containing protein 0.1977 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0067 0.0043
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0795 0.3974 0.3974
Brugia malayi ATP synthase beta chain, mitochondrial precursor, putative 0.0108 0.0469 0.0446
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0795 0.3974 0.3961
Loa Loa (eye worm) hypothetical protein 0.0056 0.0202 0.0179
Onchocerca volvulus 0.0052 0.0185 0.0153
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1977 1 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0032 0.0008
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0795 0.3974 1
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Plasmodium vivax unspecified product 0.0029 0.0067 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0055 0.0077
Brugia malayi cytokine inducible SH2-containing protein 5 0.1182 0.5945 0.5935
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1977 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Echinococcus granulosus cathepsin L 0.0029 0.0067 0.0047
Plasmodium falciparum heterochromatin protein 1 0.0027 0.0055 0.0077
Brugia malayi CHD4 protein 0.0031 0.0076 0.0052
Trypanosoma brucei DNA polymerase IV, putative 0.0045 0.0149 0.0352
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0303 0.0303
Onchocerca volvulus Tyrosine kinase homolog 0.0795 0.3974 0.3954
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0795 0.3974 0.3961
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0313 0.0764
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0055 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0795 0.3974 0.3974
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0795 0.3974 0.3961
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Schistosoma mansoni thyroid hormone receptor 0.0161 0.0741 0.0741
Schistosoma mansoni hypothetical protein 0.1182 0.5945 0.5945
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0024 0.0037
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Entamoeba histolytica receptor protein kinase, putative 0.0795 0.3974 0.3959
Schistosoma mansoni cathepsin F (C01 family) 0.0052 0.0185 0.0185
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0091 0.0385 0.0354
Echinococcus granulosus activated cdc42 kinase 1 0.0795 0.3974 0.3961
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0032 0.0008
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0795 0.3974 0.3961
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0055 0.0077
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0073 0.0122
Mycobacterium ulcerans DNA polymerase IV 0.0045 0.0149 0.2816
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0795 0.3974 0.3974
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0032 0.0032
Loa Loa (eye worm) TK protein kinase 0.0795 0.3974 0.3959
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Loa Loa (eye worm) TK protein kinase 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0031
Brugia malayi vacuolar ATP synthase subunit B 0.0077 0.0309 0.0286
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0032 0.0012
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0055 0.003
Echinococcus granulosus receptor type guanylyl cyclase 0.0795 0.3974 0.3961
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Plasmodium falciparum V-type proton ATPase catalytic subunit A 0.0051 0.018 0.0394
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0795 0.3974 0.3959
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.3959
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0795 0.3974 0.3961
Loa Loa (eye worm) RGC/RGC protein kinase 0.0795 0.3974 0.3959
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0795 0.3974 1
Trichomonas vaginalis chromobox protein, putative 0.0163 0.075 0.1839
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0093 0.0175
Echinococcus multilocularis ATP synthase subunit beta, mitochondrial 0.0108 0.0469 0.045
Loa Loa (eye worm) heterochromatin protein 1 0.0163 0.075 0.0728
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0067 0.0043
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0055 0.0077
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0093 0.0175
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0714 0.0714
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0029 0.0067 0.0144
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0026 0.005 0.0579
Onchocerca volvulus 0.0795 0.3974 0.3954
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Schistosoma mansoni tyrosine protein kinase 0.0795 0.3974 0.3974
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Onchocerca volvulus Cathepsin L homolog 0.0052 0.0185 0.0153
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0032 0.0012
Brugia malayi Cytochrome P450 family protein 0.0023 0.0034 0.001
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.1182 0.5945 0.5932
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0032 0.0032
Echinococcus multilocularis vacuolar ATP synthase subunit b 0.0077 0.0309 0.029
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0063 0.0043
Schistosoma mansoni suppressor of cytokine signaling 0.1182 0.5945 0.5945
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0054 0.0192 0.0172
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0054 0.0192 0.0172
Brugia malayi Protein kinase domain containing protein 0.1977 1 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0795 0.3974 0.3959
Treponema pallidum flagellum-specific ATP synthase (fliI) 0.0108 0.0469 1
Echinococcus multilocularis protein tyrosine kinase 0.0795 0.3974 0.3961
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Echinococcus multilocularis tyrosine kinase 0.1977 1 1
Loa Loa (eye worm) STAT protein 0.1182 0.5945 0.5935
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Plasmodium vivax ATP synthase subunit beta, mitochondrial, putative 0.0108 0.0469 0.1126
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0795 0.3974 0.3954
Trypanosoma cruzi protein kinase, putative 0.0795 0.3974 1
Trypanosoma cruzi V-type ATPase, A subunit, putative 0.0051 0.018 0.0429
Brugia malayi Variant SH3 domain containing protein 0.1182 0.5945 0.5935
Echinococcus granulosus ephrin type A receptor 4 A 0.0795 0.3974 0.3961
Loa Loa (eye worm) TK/Met protein kinase 0.0795 0.3974 0.3959
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1977 1 1
Entamoeba histolytica hypothetical protein 0.0027 0.0055 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.005 0.0065
Echinococcus multilocularis SH2 motif 0.1182 0.5945 0.5937
Wolbachia endosymbiont of Brugia malayi ATP synthase F0F1 subunit beta 0.0108 0.0469 1
Schistosoma mansoni tyrosine kinase 0.1977 1 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0052 0.0185 0.0165
Brugia malayi Raf kinase 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0008
Trypanosoma brucei Vacuolar proton pump subunit B, putative 0.0077 0.0309 0.0756
Onchocerca volvulus 0.1977 1 1
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0113 0.0495 0.0475
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0032 0.0008
Trichomonas vaginalis protein kinase atn1, putative 0.0795 0.3974 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0104 0.0203
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0055 0.0077
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0084 0.0348 0.0328
Loa Loa (eye worm) hypothetical protein 0.0249 0.1186 0.1165
Plasmodium vivax vivapain-1 0.0029 0.0067 0.0107
Brugia malayi cathepsin B-like cysteine proteinase 0.0156 0.0714 0.0692
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Mycobacterium leprae PROBABLE ATP SYNTHASE BETA CHAIN ATPD 0.0133 0.0597 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0052 0.0185 0.0407
Onchocerca volvulus 0.1977 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0032 0.0008
Toxoplasma gondii cathepsin B 0.0057 0.0211 0.0532
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0067 0.0043
Treponema pallidum transcription termination factor Rho 0.0022 0.003 0.0138
Loa Loa (eye worm) TK/ABL protein kinase 0.1977 1 1
Plasmodium falciparum ATP synthase F1, alpha subunit 0.0076 0.0308 0.0719
Schistosoma mansoni tyrosine kinase 0.1977 1 1
Brugia malayi SH2 domain containing protein 0.1182 0.5945 0.5935
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0795 0.3974 1
Toxoplasma gondii protein kinase 0.0795 0.3974 1
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1182 0.5945 0.5945
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0027 0.0055 0.0077
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0031 0.0076 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Plasmodium vivax vacuolar ATP synthase subunit b, putative 0.0077 0.0309 0.0722
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0056 0.0202 0.0182
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0084 0.0348 0.0328
Schistosoma mansoni tyrosine kinase 0.1977 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Echinococcus granulosus N chimaerin 0.1182 0.5945 0.5937
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0032 0.0012
Mycobacterium tuberculosis Probable ATP synthase alpha chain AtpA 0.0076 0.0308 0.4954
Schistosoma mansoni chromobox protein 0.0027 0.0055 0.0055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0289 0.0289
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0185 0.0407
Trichomonas vaginalis chromobox protein, putative 0.0098 0.042 0.1003
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.1182 0.5945 0.5937
Trichomonas vaginalis Heterochromatin protein, putative 0.0027 0.0055 0.0077
Schistosoma mansoni serine/threonine RGC 0.0795 0.3974 0.3974
Brugia malayi Cathepsin L-like cysteine proteinase 0.0036 0.0104 0.008
Loa Loa (eye worm) TK/INSR protein kinase 0.0795 0.3974 0.3959
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Loa Loa (eye worm) helicase 0.0027 0.0055 0.0031
Toxoplasma gondii exonuclease III APE 0.0021 0.0024 0.0061
Trypanosoma cruzi V-type proton ATPase subunit B, putative 0.0077 0.0309 0.0756
Loa Loa (eye worm) SH2 domain-containing protein 0.1182 0.5945 0.5935
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0032 0.0012
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.005 0.0449
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0031
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0795 0.3974 0.3961
Echinococcus multilocularis heat shock protein 70 0.0795 0.3974 0.3961
Entamoeba histolytica hypothetical protein 0.0026 0.005 0.0026
Echinococcus multilocularis cathepsin L 0.0029 0.0067 0.0047
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Trichomonas vaginalis STE family protein kinase 0.0795 0.3974 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Schistosoma mansoni cathepsin F (C01 family) 0.0052 0.0185 0.0185
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0185 0.0407
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Mycobacterium ulcerans transcription termination factor Rho 0.0022 0.003 0.0138
Giardia lamblia Kinase 0.0795 0.3974 1
Loa Loa (eye worm) RhoGAP domain-containing protein 0.1182 0.5945 0.5935
Brugia malayi M-phase phosphoprotein, mpp8 0.0027 0.0055 0.003
Onchocerca volvulus 0.1182 0.5945 0.5932
Brugia malayi Valyl-tRNA synthetase 0.0027 0.0055 0.003
Brugia malayi nuclear receptor NHR-88 0.0022 0.0032 0.0008
Onchocerca volvulus 0.1977 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Loa Loa (eye worm) hypothetical protein 0.0175 0.081 0.0788
Onchocerca volvulus 0.0052 0.0185 0.0153
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.005 0.0579
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0032 0.0032
Echinococcus multilocularis chromobox protein 1 0.0163 0.075 0.0732
Trypanosoma brucei DNA polymerase IV, putative 0.0045 0.0149 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0795 0.3974 1
Loa Loa (eye worm) TK protein kinase 0.1977 1 1
Brugia malayi Cytochrome P450 family protein 0.0023 0.0034 0.001
Trichomonas vaginalis chromobox protein, putative 0.0098 0.042 0.1003
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0795 0.3974 0.3961
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Echinococcus multilocularis microtubule associated protein 2 0.1616 0.8158 0.8155
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Schistosoma mansoni shc transforming protein 0.1182 0.5945 0.5945
Loa Loa (eye worm) TK/ACK protein kinase 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus multilocularis muscleblind protein 0.0175 0.081 0.0792
Loa Loa (eye worm) TK/RYK protein kinase 0.0795 0.3974 0.3959
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1977 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0185 0.0161
Echinococcus granulosus ATP synthase subunit alpha mitochondrial 0.0076 0.0308 0.0288
Giardia lamblia Kinase, NEK 0.0795 0.3974 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1977 1 1
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0027 0.0055 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0093 0.0175
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1182 0.5945 0.5945
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0795 0.3974 1
Brugia malayi Cathepsin L-like precursor 0.0052 0.0185 0.0161
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0032 0.0032
Entamoeba histolytica hypothetical protein 0.0795 0.3974 0.3959
Brugia malayi Pre-SET motif family protein 0.0036 0.01 0.0076
Loa Loa (eye worm) TK protein kinase 0.0795 0.3974 0.3959
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0795 0.3974 0.3961
Echinococcus multilocularis ATP synthase subunit alpha, mitochondrial 0.0076 0.0308 0.0288
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0032 0.0012
Chlamydia trachomatis V-type ATP synthase subunit A 0.0051 0.018 0.3409
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1182 0.5945 0.5935
Echinococcus granulosus cathepsin b 0.0156 0.0714 0.0695
Echinococcus multilocularis activin receptor type 0.0795 0.3974 0.3961
Brugia malayi hypothetical protein 0.1977 1 1
Onchocerca volvulus 0.0092 0.0386 0.0355
Echinococcus granulosus tyrosine protein kinase csk 0.0795 0.3974 0.3961
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0034 0.001
Brugia malayi hypothetical protein 0.0084 0.0348 0.0325
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0093 0.0211
Echinococcus multilocularis epidermal growth factor receptor 0.0795 0.3974 0.3961
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0032 0.0008
Giardia lamblia DINP protein human, muc B family 0.0023 0.0037 0.0032
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Trichomonas vaginalis conserved hypothetical protein 0.0795 0.3974 1
Brugia malayi nuclear hormone receptor 0.0022 0.0032 0.0008
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0092 0.0386 0.0386
Echinococcus granulosus cathepsin L cysteine protease 0.0029 0.0067 0.0047
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0024 0.0004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0054 0.0192 0.0172
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0027 0.0055 0.0034
Echinococcus granulosus cathepsin l cysteine peptidase 0.0052 0.0185 0.0165
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0795 0.3974 0.3961
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0093 0.0211
Toxoplasma gondii cathepsin CPL 0.0052 0.0185 0.0466
Trypanosoma cruzi ATP synthase F1, alpha subunit, putative 0.0022 0.003 0.0052
Trichomonas vaginalis set domain proteins, putative 0.0278 0.1336 0.3322
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Onchocerca volvulus 0.0036 0.0104 0.0072
Trichomonas vaginalis ATP synthase, putative 0.0077 0.0309 0.0722
Onchocerca volvulus 0.0795 0.3974 0.3954
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0795 0.3974 0.3974
Giardia lamblia Cathepsin B precursor 0.0057 0.0211 0.0473
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0795 0.3974 0.3974
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0098 0.042 0.0389
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0795 0.3974 0.3961
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0032 0.0008
Loa Loa (eye worm) hypothetical protein 0.0075 0.0303 0.028
Echinococcus multilocularis L aminoadipate semialdehyde 0.0092 0.0386 0.0367
Schistosoma mansoni signal transduction protein lnk-related 0.1182 0.5945 0.5945
Loa Loa (eye worm) hypothetical protein 0.0048 0.0162 0.0138
Onchocerca volvulus 0.0052 0.0185 0.0153
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.005 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.0795 0.3974 0.3974
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0124
Echinococcus granulosus chromobox protein 2 0.0027 0.0055 0.0034
Echinococcus multilocularis tyrosine protein kinase 0.0795 0.3974 0.3961
Brugia malayi chromobox protein homolog 3 0.0091 0.0385 0.0361
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus multilocularis tensin 0.1182 0.5945 0.5937
Entamoeba histolytica cysteine protease, putative 0.0029 0.0067 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0093 0.0175
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.0185 0.0162
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Mycobacterium leprae conserved hypothetical protein 0.0026 0.005 0.0346
Schistosoma mansoni cpg binding protein 0.0038 0.0111 0.0111
Echinococcus granulosus tyrosine kinase 0.1977 1 1
Onchocerca volvulus 0.0027 0.0055 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0055 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0032 0.0008
Schistosoma mansoni cpg binding protein 0.0038 0.0111 0.0111
Brugia malayi polk-prov protein 0.0034 0.0093 0.0069
Loa Loa (eye worm) TK protein kinase 0.0795 0.3974 0.3959
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1977 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0795 0.3974 0.3961
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0032 0.0008
Entamoeba histolytica tyrosine kinase, putative 0.0795 0.3974 0.3959
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0714 0.0714
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0057 0.0211 0.0473
Echinococcus granulosus zinc finger protein 0.0025 0.0045 0.0025
Brugia malayi Heterochromatin protein 1 0.0163 0.075 0.0728
Brugia malayi hypothetical protein 0.0027 0.0055 0.003
Brugia malayi Protein kinase domain containing protein 0.1977 1 1
Loa Loa (eye worm) hypothetical protein 0.0795 0.3974 0.3959
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Loa Loa (eye worm) TK/FER protein kinase 0.1977 1 1
Onchocerca volvulus 0.0795 0.3974 0.3954
Schistosoma mansoni protein tyrosine kinase 0.0795 0.3974 0.3974
Schistosoma mansoni tensin-related 0.1182 0.5945 0.5945
Echinococcus multilocularis growth factor receptor bound protein 2 0.1182 0.5945 0.5937
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.1977 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Leishmania major cathepsin L-like protease 0.0052 0.0185 0.0442
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0027 0.0055 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0055 0.0077
Schistosoma mansoni hypothetical protein 0.0024 0.0042 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0032 0.0008
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0795 0.3974 1
Echinococcus granulosus survival motor neuron protein 1 0.0246 0.1174 0.1156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Echinococcus multilocularis receptor type guanylyl cyclase 0.0795 0.3974 0.3961
Echinococcus granulosus cathepsin L cysteine proteinase 0.0052 0.0185 0.0165
Brugia malayi SH2 domain containing protein 0.1182 0.5945 0.5935
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0077 0.0313 0.0293
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0032 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0055 0.0077
Entamoeba histolytica protein kinase, putative 0.0795 0.3974 0.3959
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0067 0.0043
Loa Loa (eye worm) hypothetical protein 0.1182 0.5945 0.5935
Schistosoma mansoni protein kinase 0.0795 0.3974 0.3974
Entamoeba histolytica hypothetical protein 0.0084 0.0348 0.0325
Echinococcus multilocularis SH2 domain containing protein 7 0.1182 0.5945 0.5937
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1977 1 1
Brugia malayi tRNA modification GTPase TrmE family protein 0.1182 0.5945 0.5935
Brugia malayi hypothetical protein 0.0249 0.1186 0.1165
Schistosoma mansoni ephrin receptor 0.0795 0.3974 0.3974
Loa Loa (eye worm) cathepsin B 0.0057 0.0211 0.0188
Schistosoma mansoni tyrosine kinase 0.0795 0.3974 0.3974
Echinococcus multilocularis tyrosine kinase 0.0795 0.3974 0.3961
Plasmodium falciparum tyrosine kinase-like protein 0.0795 0.3974 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Trypanosoma cruzi ATPase beta subunit, putative 0.0022 0.003 0.0052
Echinococcus granulosus tensin C1 domain containing phosphatase 0.1182 0.5945 0.5937
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Schistosoma mansoni lozenge 0.0065 0.025 0.025
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0027 0.0055 0.0077
Entamoeba histolytica tyrosin kinase, putative 0.0795 0.3974 0.3959
Brugia malayi Cathepsin L-like precursor 0.0052 0.0185 0.0161
Echinococcus multilocularis thyroid hormone receptor alpha 0.0161 0.0741 0.0722
Plasmodium falciparum protein kinase, putative 0.0795 0.3974 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0185 0.0407
Echinococcus granulosus suppressor of cytokine signaling 7 0.1182 0.5945 0.5937
Echinococcus granulosus c src tyrosine kinase 0.1977 1 1
Schistosoma mansoni cpg binding protein 0.0034 0.009 0.009
Entamoeba histolytica serine/threonine kinase, putative 0.0795 0.3974 0.3959
Loa Loa (eye worm) fibroinase 0.0052 0.0185 0.0162
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0185 0.0442
Onchocerca volvulus 0.0795 0.3974 0.3954
Echinococcus granulosus cathepsin l1 0.0052 0.0185 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0149 0.0352
Echinococcus multilocularis Chromo domain 0.0027 0.0055 0.0034
Entamoeba histolytica receptor protein kinase, putative 0.0795 0.3974 0.3959
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0032 0.0032
Echinococcus granulosus chromobox protein 1 0.0163 0.075 0.0732
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0024 0.0004
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0027 0.0055 0.0055
Schistosoma mansoni ephrin receptor 0.0795 0.3974 0.3974
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0185 0.0407
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0185 0.0442
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1977 1 1
Echinococcus granulosus chromobox protein 1 0.0163 0.075 0.0732
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0045 0.0149 0.0317
Brugia malayi Protein kinase domain containing protein 0.0795 0.3974 0.3959
Schistosoma mansoni GTPase activating protein 0.1182 0.5945 0.5945
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0063 0.0063
Onchocerca volvulus 0.1182 0.5945 0.5932
Entamoeba histolytica ankyrin repeat protein 0.0795 0.3974 0.3959
Echinococcus granulosus epidermal growth factor receptor 0.0795 0.3974 0.3961
Trichomonas vaginalis TKL family protein kinase 0.0795 0.3974 1
Echinococcus granulosus cathepsin l1 0.0036 0.0104 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0032 0.0008
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.3974 0.3959
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0104 0.008

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) > 30 uM Cytotoxicity of the compound measured against human T-cells ChEMBL. 11356112
IC50 (binding) = 1.1 uM In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrate ChEMBL. 11356112
IC50 (functional) > 30 uM In vitro inhibition of human T-cell proliferation ChEMBL. 11356112

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.