Detailed information for compound 834271

Basic information

Technical information
  • TDR Targets ID: 834271
  • Name: 2-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfon ylamino]-3-phenyl-N-propylpropanamide
  • MW: 415.506 | Formula: C21H25N3O4S
  • H donors: 3 H acceptors: 4 LogP: 2.26 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCNC(=O)C(NS(=O)(=O)c1ccc2c(c1)CCC(=O)N2)Cc1ccccc1
  • InChi: 1S/C21H25N3O4S/c1-2-12-22-21(26)19(13-15-6-4-3-5-7-15)24-29(27,28)17-9-10-18-16(14-17)8-11-20(25)23-18/h3-7,9-10,14,19,24H,2,8,11-13H2,1H3,(H,22,26)(H,23,25)
  • InChiKey: MOLWIFIRQYWJNC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfonylamino]-3-phenyl-N-propyl-propanamide
  • 2-[(2-keto-3,4-dihydro-1H-quinolin-6-yl)sulfonylamino]-3-phenyl-N-propyl-propionamide
  • MLS000118187
  • SMR000095135

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni biogenic amine receptor 0.0015 0.0036 0.0011
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0015 0.0032 0.0072
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0186 0.1254 0.1499
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0392 0.0469
Brugia malayi RE15519p 0.0015 0.0036 0.0011
Echinococcus granulosus orexin receptor type 2 0.0015 0.0036 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0099 0.0303
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0939 0.663 0.7926
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0015 0.0032 0.0038
Schistosoma mansoni DNA polymerase eta 0.002 0.0069 0.0051
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0052 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0197
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0036 0.0011
Echinococcus multilocularis somatostatin receptor 0.0015 0.0036 0.0043
Brugia malayi PHD-finger family protein 0.005 0.0282 0.0305
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0052 0.0031
Schistosoma mansoni hypothetical protein 0.0042 0.0225 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0197
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0238 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.0036 0.0043
Schistosoma mansoni neuropeptide receptor 0.0015 0.0036 0.0011
Mycobacterium tuberculosis Conserved protein 0.0043 0.0238 0.1187
Echinococcus multilocularis dna polymerase eta 0.002 0.0069 0.0082
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.005
Brugia malayi Dopamine receptor protein 1 0.0015 0.0036 0.0011
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0019 0.0066 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0052 0.0055
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0017 0.0052 0.0055
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Schistosoma mansoni ap endonuclease 0.0015 0.0032 0.0007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1943 0.6318
Echinococcus granulosus zinc finger protein 0.0035 0.0178 0.0212
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0036 0.0043
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0124 0.0813 0.0937
Echinococcus multilocularis jumonji domain containing protein 0.0069 0.0421 0.0504
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0026 0.0026
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0124 0.0813 0.0937
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0179 0.0179
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Loa Loa (eye worm) helicase 0.0019 0.0066 0.0066
Leishmania major DNA polymerase eta, putative 0.002 0.0069 0.005
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0124 0.0813 0.096
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0052 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0815 0.5744 0.6812
Trichomonas vaginalis glucosylceramidase, putative 0.044 0.3071 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0238 0.0252
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0163 0.109 0.1303
Onchocerca volvulus 0.0043 0.0238 0.0253
Schistosoma mansoni hypothetical protein 0.0015 0.0036 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0066 0.0507
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0036 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.044 0.3071 1
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0042 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.044 0.3071 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0114 0.0353
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.01 0.0642 0.0734
Loa Loa (eye worm) PHD-finger family protein 0.005 0.0282 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0197
Entamoeba histolytica hypothetical protein 0.01 0.0642 0.3214
Onchocerca volvulus 0.0186 0.1254 0.1472
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Plasmodium falciparum phosphodiesterase gamma, putative 0.0124 0.0813 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0086 0.0539 0.0645
Brugia malayi jmjC domain containing protein 0.0065 0.0392 0.0436
Onchocerca volvulus 0.0086 0.0539 0.0615
Onchocerca volvulus 0.0015 0.0036 0.0011
Brugia malayi neuropeptide F receptor 0.0015 0.0036 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0264 0.0284
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0124 0.0813 0.0944
Schistosoma mansoni neurotransmitter gated ion channel 0.0086 0.0539 0.0615
Loa Loa (eye worm) hypothetical protein 0.0074 0.0459 0.0459
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus expressed conserved protein 0.0095 0.0604 0.0722
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0186 0.1254 0.1499
Brugia malayi Bromodomain containing protein 0.013 0.0852 0.0984
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.0075
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0036 0.0043
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus granulosus glycine receptor subunit alpha 1 0.0186 0.1254 0.1499
Schistosoma mansoni 6-phosphofructokinase 0.0127 0.0833 0.0967
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0238 0.1187
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0017 0.0047 0.0024
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0052 0.0031
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0086 0.0539 0.0645
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0346 0.1758
Onchocerca volvulus 0.0015 0.0036 0.0011
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0186 0.1254 0.1499
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0036 0.0011
Echinococcus multilocularis chromobox protein 1 0.0119 0.0776 0.0927
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0036 0.0043
Schistosoma mansoni amine GPCR 0.0015 0.0036 0.0011
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0016 0.0043 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0264 0.0284
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0042 0.005
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0362 0.0538
Echinococcus multilocularis geminin 0.0487 0.3401 0.4066
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.199 0.6473
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0186 0.1254 0.1472
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0172 0.1851
Brugia malayi hypothetical protein 0.0086 0.0539 0.0611
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0124 0.0813 0.2634
Brugia malayi excitatory GABA receptor EXP-1A 0.0186 0.1254 0.1463
Loa Loa (eye worm) hypothetical protein 0.01 0.0642 0.0642
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0191 0.0228
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0114 0.0353
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0172 0.1851
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0069 0.0221
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0017 0.0047 0.0024
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0026 0.0072
Schistosoma mansoni hypothetical protein 0.0042 0.0225 0.0239
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0017 0.0052 0.0031
Entamoeba histolytica phosphofructokinase, putative 0.0127 0.0833 0.4208
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0939 0.663 1
Echinococcus multilocularis muscleblind protein 1 0.0153 0.1021 0.122
Brugia malayi 6-phosphofructokinase 0.0127 0.0833 0.0961
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0815 0.5744 0.6867
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0346 0.0414
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0036 0.0043
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0017 0.0047 0.0258
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0124 0.0813 0.0937
Schistosoma mansoni nAChR subunit 0.0086 0.0539 0.0615
Loa Loa (eye worm) hypothetical protein 0.01 0.0642 0.0642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Giardia lamblia GTOR 0.0017 0.0052 0.003
Trichomonas vaginalis ap endonuclease, putative 0.0015 0.0032 0.0086
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0439 0.1413
Schistosoma mansoni zinc finger protein 0.0035 0.0178 0.0182
Onchocerca volvulus 0.0186 0.1254 0.1472
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0186 0.1254 0.1472
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0036 0.0043
Entamoeba histolytica hypothetical protein 0.0019 0.0066 0.0208
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0186 0.1254 0.1472
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0089 0.0704
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Echinococcus multilocularis tumor protein p63 0.0346 0.24 0.2869
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0019 0.0066 0.0048
Leishmania major hypothetical protein, conserved 0.0043 0.0238 0.0252
Leishmania major ATP-dependent phosphofructokinase 0.0127 0.0833 0.0961
Echinococcus granulosus somatostatin receptor 0.0015 0.0036 0.0043
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0042 0.0019
Plasmodium falciparum heterochromatin protein 1 0.0019 0.0066 0.0507
Onchocerca volvulus 0.0015 0.0036 0.0011
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0036 0.0043
Schistosoma mansoni hypothetical protein 0.0019 0.0066 0.0048
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0036 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0264 0.1093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0099 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0025 0.0023
Schistosoma mansoni cpg binding protein 0.0034 0.0173 0.0176
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0052 0.0031
Brugia malayi hypothetical protein 0.0086 0.0539 0.0611
Schistosoma mansoni neurotransmitter gated ion channel 0.01 0.0642 0.0738
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0075
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0179 1
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0403 0.1295
Onchocerca volvulus 0.0052 0.03 0.0328
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0052 0.0031
Onchocerca volvulus 0.0015 0.0036 0.0011
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0036 0.0043
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0124 0.0813 0.0937
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0042 0.0042
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.008 0.0498 0.0562
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.1943 1
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0113 0.0731 0.0839
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0036 0.0011
Loa Loa (eye worm) apoptosis regulator protein 0.008 0.0498 0.0498
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0067 0.0403 0.0451
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0036 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0036 0.0011
Giardia lamblia DINP protein human, muc B family 0.002 0.0069 0.0056
Leishmania major hypothetical protein, conserved 0.0016 0.0042 0.0019
Brugia malayi Cation transporter family protein 0.0186 0.1254 0.1463
Loa Loa (eye worm) hypothetical protein 0.0051 0.0289 0.0289
Brugia malayi Protein cec-1. 0.0019 0.0066 0.0048
Echinococcus multilocularis muscleblind protein 0.0153 0.1021 0.122
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0365 0.0436
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Brugia malayi sulfakinin receptor protein 0.0015 0.0036 0.0011
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0264 0.2688
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0036 0.0036
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0069 0.0082
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0114 0.0353
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0036 0.0043
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0939 0.663 0.7926
Mycobacterium ulcerans 6-phosphofructokinase 0.0127 0.0833 0.3703
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0017 0.0052 0.0031
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Leishmania major C-8 sterol isomerase-like protein 0.119 0.8421 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0322 0.0354
Trichomonas vaginalis glucosylceramidase, putative 0.044 0.3071 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0536 0.0536
Onchocerca volvulus 0.0029 0.0138 0.0133
Mycobacterium ulcerans hypothetical protein 0.0047 0.0264 0.1093
Brugia malayi Pre-SET motif family protein 0.0029 0.0138 0.0133
Echinococcus granulosus glycine receptor subunit alpha 1 0.0186 0.1254 0.1499
Brugia malayi Bromodomain containing protein 0.0054 0.0311 0.0339
Schistosoma mansoni hypothetical protein 0.0419 0.2921 0.3471
Leishmania major hypothetical protein, conserved 0.0124 0.0813 0.0937
Brugia malayi hypothetical protein 0.0037 0.0191 0.0196
Onchocerca volvulus 0.0043 0.0238 0.0253
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0025 0.0023
Onchocerca volvulus 0.0015 0.0036 0.0011
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.008 0.0498 0.0596
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0019 0.0066 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0264 0.1093
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0238 0.0253
Echinococcus granulosus Chromo domain 0.0019 0.0066 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0264 0.0842
Schistosoma mansoni hypothetical protein 0.0015 0.0036 0.0011
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.044 0.3071 0.3627
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0264 0.0284
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0042 0.005
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0017 0.0052 0.0031
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0026 0.0067
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0815 0.5744 0.6867
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0179
Loa Loa (eye worm) 6-phosphofructokinase 0.0127 0.0833 0.0833
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0026 0.0072
Schistosoma mansoni myosin xvIII 0.0015 0.0036 0.0011
Schistosoma mansoni amine GPCR 0.0015 0.0036 0.0011
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0172 0.9202
Schistosoma mansoni DNA helicase recq1 0.0017 0.0047 0.0024
Onchocerca volvulus 0.0019 0.0066 0.0048
Onchocerca volvulus 0.0345 0.2391 0.2835
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0124 0.0813 0.0972
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0179 0.0702
Schistosoma mansoni glutaminase 0.0319 0.2204 0.2611
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0179
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0124 0.0813 0.0944
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0238 0.0252
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0036 0.0043
Entamoeba histolytica phosphofructokinase, putative 0.0127 0.0833 0.4208
Onchocerca volvulus Alhambra homolog 0.005 0.0282 0.0307
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Onchocerca volvulus 0.0186 0.1254 0.1472
Onchocerca volvulus 0.0229 0.1565 0.1845
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0036 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0172 0.0542
Brugia malayi beta-lactamase family protein 0.0043 0.0238 0.0252
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0026 0.0067
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0238 0.0284
Entamoeba histolytica hypothetical protein 0.0037 0.0191 0.0858
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0077 0.0092
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0238 0.1187
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0036 0.0036
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0069 0.0082
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0124 0.0813 0.0937
Echinococcus multilocularis Protein lozenge 0.0043 0.0236 0.0283
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0179 0.1942
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0113 0.0731 0.0839
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0089 0.0074
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0015 0.0032 0.0038
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0124 0.0813 0.096
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0322 0.0384
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0069 0.0205
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0092 0.0281
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0036 0.0011
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0069 0.0194
Echinococcus granulosus L aminoadipate semialdehyde 0.008 0.0501 0.0599
Loa Loa (eye worm) 6-phosphofructokinase 0.0127 0.0833 0.0833
Onchocerca volvulus 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0066
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0036 0.0011
Giardia lamblia PHD finger protein 15 0.005 0.0282 0.0379
Entamoeba histolytica hypothetical protein 0.0037 0.0191 0.0858
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0238 0.0757
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Brugia malayi AF-10 protein 0.0016 0.0043 0.002
Echinococcus granulosus chromobox protein 2 0.0019 0.0066 0.0079
Schistosoma mansoni nAChR subunit 0.0186 0.1254 0.1472
Schistosoma mansoni chromobox protein 0.0119 0.0776 0.0898
Trichomonas vaginalis chromobox protein, putative 0.0019 0.0066 0.0197
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) bromodomain containing protein 0.003 0.0142 0.0142
Echinococcus multilocularis protein patched 0.0043 0.0237 0.0283
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trichomonas vaginalis ap endonuclease, putative 0.0015 0.0032 0.0086
Brugia malayi G-protein coupled receptor 0.0015 0.0036 0.0011
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0017 0.0047 0.0056
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0264 0.1093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Schistosoma mansoni nAChR subunit 0.0186 0.1254 0.1472
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.199 0.6473
Loa Loa (eye worm) PDE1B protein 0.0124 0.0813 0.0813
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0036 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0833 0.2697
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Brugia malayi Muscleblind-like protein 0.0153 0.1021 0.1184
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0186 0.1254 0.1472
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0238 0.0238
Brugia malayi CHE-14 protein 0.0043 0.0237 0.025
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Mycobacterium ulcerans glutaminase 0.0319 0.2204 1
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0042 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0124 0.0813 0.0937
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0172 0.0542
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0042 0.0019
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0086 0.0539 0.0539
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0036 0.0043
Schistosoma mansoni nAChR subunit 0.0186 0.1254 0.1472
Brugia malayi AKH receptor 0.0015 0.0036 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0124 0.0813 0.0944
Schistosoma mansoni nAChR subunit 0.0186 0.1254 0.1472
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0186 0.1254 0.1254
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0036 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0124 0.0813 0.0937
Mycobacterium tuberculosis Conserved protein 0.0043 0.0238 0.1187
Echinococcus multilocularis dna polymerase kappa 0.002 0.0069 0.0082
Schistosoma mansoni nAChR subunit 0.0186 0.1254 0.1472
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.044 0.3071 0.3071
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0026 0.0072
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0186 0.1254 0.1463
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.005
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0099 0.014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0103 0.0092
Entamoeba histolytica hypothetical protein 0.0019 0.0066 0.0208
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0179 0.0878
Trypanosoma brucei unspecified product 0.0014 0.0025 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0059 0.0345 0.0345
Treponema pallidum fructose-bisphosphate aldolase 0.0282 0.1943 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0264 0.1093
Giardia lamblia Hypothetical protein 0.0124 0.0813 0.1184
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0186 0.1254 0.1463
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0036 0.0011
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0036 0.0036
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0042 0.0198
Loa Loa (eye worm) hypothetical protein 0.0014 0.0026 0.0026
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.008 0.0498 0.0566
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.01 0.0642 0.0734
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0124 0.0813 0.0937
Trypanosoma cruzi hypothetical protein, conserved 0.0124 0.0813 0.0937
Echinococcus granulosus chromobox protein 1 0.0119 0.0776 0.0927
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0042 0.0019
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0103 0.0659 0.0759
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0099 0.0118
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0501 0.0501
Brugia malayi Bromodomain containing protein 0.0065 0.0394 0.0438
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0238 0.0757
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0017 0.0047 0.0258
Mycobacterium ulcerans hypothetical protein 0.0043 0.0238 0.0971
Loa Loa (eye worm) hypothetical protein 0.0067 0.0403 0.0403
Schistosoma mansoni biogenic amine receptor 0.0015 0.0036 0.0011
Brugia malayi hypothetical protein 0.0086 0.0539 0.0611
Echinococcus granulosus allatostatin A receptor 0.0015 0.0036 0.0043
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0052 0.0031
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0186 0.1254 0.1499
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0042 0.005
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0186 0.1254 0.1463
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0075
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0086 0.0539 0.0645
Loa Loa (eye worm) ACC-1 protein 0.0186 0.1254 0.1254
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0124 0.0813 0.0937
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0036 0.0043
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0124 0.0813 0.0944
Echinococcus granulosus serotonin receptor 0.0015 0.0036 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0197
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0124 0.0813 0.0972
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0015 0.0032 0.0102
Trichomonas vaginalis chromobox protein, putative 0.0119 0.0776 0.2511
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0113 0.0731 0.0839
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0237 0.0283
Echinococcus granulosus g protein coupled receptor 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0019 0.0066 0.0048
Loa Loa (eye worm) hypothetical protein 0.0069 0.0423 0.0423
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0939 0.663 0.7926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0186 0.1254 0.1463
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.01 0.0642 0.0734
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0124 0.0813 0.0972
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0042 0.005
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Onchocerca volvulus 0.008 0.0501 0.0569
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0066
Trichomonas vaginalis set domain proteins, putative 0.0229 0.1565 0.5087
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0172 0.0542
Echinococcus multilocularis serotonin receptor 0.0015 0.0036 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0138 0.0199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0036 0.0011
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0114 0.0353
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0124 0.0813 0.0937
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0069 0.0295
Onchocerca volvulus 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0179
Leishmania major hypothetical protein, conserved 0.0026 0.0114 0.0104
Echinococcus multilocularis sex peptide receptor 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0749 0.5272 0.5272
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0346 0.0514
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0089 0.0792
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0036 0.0011
Schistosoma mansoni amine GPCR 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0608 0.4269 0.4269
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0186 0.1254 0.1499
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0036 0.0011
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0089 0.0296
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0127 0.0833 0.4322
Loa Loa (eye worm) oxidoreductase 0.0014 0.0026 0.0026
Brugia malayi G protein-coupled receptor 0.0015 0.0036 0.0011
Brugia malayi 6-phosphofructokinase 0.0127 0.0833 0.0961
Schistosoma mansoni apoptosis regulator bax 0.008 0.0498 0.0566
Giardia lamblia Fructose-bisphosphate aldolase 0.0282 0.1943 0.2896
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0439 0.1413
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0939 0.663 0.7919
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0238 0.1187
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0392 0.0392
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0036 0.0043
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.008 0.0498 0.0596
Schistosoma mansoni amine GPCR 0.0015 0.0036 0.0011
Trypanosoma cruzi ISWI complex protein 0.0026 0.0114 0.0104
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0186 0.1254 0.1472
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0124 0.0813 0.0944
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0036 0.0011
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0089 0.0125
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0186 0.1254 0.1499
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0813 0.2634
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0172 0.0542
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0036 0.0043
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0036 0.0036
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.01 0.0642 0.0738
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0017 0.0052 0.0055
Loa Loa (eye worm) jmjC domain-containing protein 0.0103 0.066 0.066
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0186 0.1254 0.1463
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0086 0.0539 0.0539
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0019
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0036 0.0043
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0017 0.0047 0.0049
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0086 0.0539 0.0611
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0833 0.2697
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Echinococcus multilocularis L aminoadipate semialdehyde 0.008 0.0501 0.0599
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0345 0.0383
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0026 0.0072
Onchocerca volvulus 0.0047 0.0264 0.0285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0264 0.1242
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0113 0.0731 0.0874
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.005
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0026 0.0072
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0392 0.0439
Onchocerca volvulus 0.0086 0.0539 0.0615
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0036 0.0011
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0026 0.0031
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0089 0.0098
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Entamoeba histolytica hypothetical protein 0.0019 0.0066 0.0208
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0036 0.0043
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0124 0.0813 1
Loa Loa (eye worm) hypothetical protein 0.0535 0.3746 0.3746
Echinococcus granulosus fetal alzheimer antigen falz 0.004 0.0214 0.0256
Brugia malayi putative neuropeptide receptor 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0124 0.0813 0.0937
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Brugia malayi follicle stimulating hormone receptor 0.0015 0.0036 0.0011
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0036 0.0011
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0346 0.1468
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0052 0.0062
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0052 0.0031
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0036 0.0011
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0127 0.0833 0.0983
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.0036 0.0043
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0124 0.0813 0.096
Onchocerca volvulus Glucosylceramidase homolog 0.0289 0.199 0.2355
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0165 0.0806
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Echinococcus granulosus vesicular acetylcholine transporter 0.1182 0.8365 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0019 0.0066 0.0507
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0036 0.0036
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0036 0.0043
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0036 0.0043
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.008 0.0498 0.0596
Trichomonas vaginalis chromobox protein, putative 0.0019 0.0066 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Onchocerca volvulus 0.0051 0.0289 0.0315
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.0036 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0036 0.0011
Mycobacterium tuberculosis Conserved protein 0.0043 0.0238 0.1187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0179 0.1942
Toxoplasma gondii exonuclease III APE 0.0015 0.0032 0.004
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0016 0.0043 0.0057
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.01 0.0642 0.0734
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0186 0.1254 0.1499
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0042 0.005
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0086 0.0539 0.0611
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.199 0.6473
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0036 0.0043
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0036 0.0043
Brugia malayi Cation transporter family protein 0.0186 0.1254 0.1463
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0138 0.0134
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0835 0.5884 0.5884
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0238 0.0971
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0124 0.0813 0.0937
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Schistosoma mansoni neuropeptide receptor 0.0015 0.0036 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Onchocerca volvulus 0.0015 0.0036 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0138 0.0134
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Plasmodium vivax phosphodiesterase gamma, putative 0.0124 0.0813 1
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0017 0.0052 0.0062
Schistosoma mansoni amine GPCR 0.0015 0.0036 0.0011
Brugia malayi vesicular acetylcholine transporter unc-17 0.1182 0.8365 0.9934
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0322 0.0354
Loa Loa (eye worm) hypothetical protein 0.008 0.0498 0.0498
Schistosoma mansoni 6-phosphofructokinase 0.0127 0.0833 0.0967
Loa Loa (eye worm) hypothetical protein 0.0121 0.0788 0.0788
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) hypothetical protein 0.01 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.01 0.0642 0.0642
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0322 0.0352
Onchocerca volvulus 0.0015 0.0036 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0264 0.0284
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0172 0.9202
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.008 0.0501 0.0565
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) beta-lactamase 0.0043 0.0238 0.0238
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1943 0.6318
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0053 0.0306 0.0306
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.0101 0.0121
Trypanosoma brucei C-8 sterol isomerase, putative 0.119 0.8421 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0026 0.0026
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0124 0.0813 0.0937
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0052 0.0055
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0833 0.2697
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Entamoeba histolytica hypothetical protein 0.0023 0.0089 0.0325
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0017 0.0047 0.0056
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 1
Schistosoma mansoni hypothetical protein 0.005 0.0282 0.0307
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0104 0.0666 0.0796
Schistosoma mansoni opsin-like receptor 0.0015 0.0036 0.0011
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0019 0.0066 0.0079
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0017 0.0052 0.0055
Echinococcus multilocularis chromobox protein 1 0.0119 0.0776 0.0927
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0124 0.0813 0.0972
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0042 0.0042
Brugia malayi beta-lactamase 0.0043 0.0238 0.0252
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0052 0.0031
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0172 0.076
Onchocerca volvulus 0.0186 0.1254 0.1472
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0186 0.1254 0.1254
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0264 0.0284
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.1943 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0069 0.0295
Leishmania major hypothetical protein, conserved 0.0124 0.0813 0.0937
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0026 0.0026
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0086 0.0539 0.0645
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1943 0.6318
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0186 0.1254 0.1499
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0912 1
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0089 1
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0056 0.038
Loa Loa (eye worm) hypothetical protein 0.0411 0.286 0.286
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0036 0.0043
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0238 0.0757
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0114 0.0353
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0322 0.0322
Plasmodium vivax heterochromatin protein 1, putative 0.0019 0.0066 0.0507
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Onchocerca volvulus 0.0015 0.0036 0.0011
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0238 0.1187
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0186 0.1254 0.1499
Loa Loa (eye worm) hypothetical protein 0.0101 0.0648 0.0648
Schistosoma mansoni histamine h1 receptor 0.0015 0.0036 0.0011
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0036 0.0043
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0099 0.011
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0036 0.0043
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0238 0.0757
Onchocerca volvulus 0.0086 0.0539 0.0615
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0186 0.1254 0.1463
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0036 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.199 0.6473
Onchocerca volvulus Putative nachr subunit 0.0186 0.1254 0.1472
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0017 0.0047 0.0047
Schistosoma mansoni nAChR subunit 0.0186 0.1254 0.1472
Schistosoma mansoni hypothetical protein 0.0015 0.0036 0.0011
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0124 0.0813 0.0972
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0124 0.0813 0.0944
Echinococcus granulosus g protein coupled receptor 0.0015 0.0036 0.0043
Trypanosoma brucei hypothetical protein, conserved 0.0124 0.0813 0.096
Onchocerca volvulus 0.0019 0.0066 0.0048
Onchocerca volvulus 0.0015 0.0036 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0322 0.0354
Brugia malayi Heterochromatin protein 1 0.0119 0.0776 0.0892
Loa Loa (eye worm) hypothetical protein 0.0124 0.0813 0.0813
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0017 0.0052 0.0031
Schistosoma mansoni hypothetical protein 0.0042 0.0225 0.0239
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0113 0.0731 0.3677
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0019 0.0066 0.0048
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Schistosoma mansoni cpg binding protein 0.0029 0.0138 0.0133
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0264 0.1327
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0086 0.0539 0.0611
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1943 0.6318
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0066 0.0507
Echinococcus multilocularis 6 phosphofructokinase 0.0127 0.0833 0.0995
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0124 0.0813 0.0937
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0069 0.0205
Schistosoma mansoni acetylcholine receptor subunit beta 0.0086 0.0539 0.0615
Trypanosoma cruzi C-8 sterol isomerase, putative 0.119 0.8421 1
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.199 0.6473
Echinococcus granulosus dnaJ subfamily B 0.0419 0.2921 0.3491
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0036 0.0043
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0036 0.0043
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0026 0.0072
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0089 0.0286
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0088 0.0269
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0069 0.005
Loa Loa (eye worm) runx1 0.0043 0.0236 0.0236
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0815 0.5744 0.5744
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0069
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0052 0.0052
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0019 0.0066 0.0079
Loa Loa (eye worm) hypothetical protein 0.0043 0.0238 0.0238
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0066 0.0208
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0036 0.0011
Schistosoma mansoni chromobox protein 0.0019 0.0066 0.0048
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0648 0.0774
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0089 0.0401
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0015 0.0032 0.0026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0086 0.0539 0.0611
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0015 0.0032 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0036 0.0043
Echinococcus multilocularis Chromobox protein 3 0.0019 0.0066 0.0079
Trichomonas vaginalis DNA helicase recq, putative 0.0017 0.0047 0.0133
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0099 0.0118
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Brugia malayi CHD4 protein 0.0024 0.0101 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1943 0.6318
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0264 0.0284
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0114 0.0353
Echinococcus multilocularis Chromo domain 0.0019 0.0066 0.0079
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0015 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0047 0.0264 0.0264
Echinococcus granulosus glycine receptor subunit alpha 1 0.0186 0.1254 0.1499
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Schistosoma mansoni neuropeptide receptor 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0345 0.2391 0.2391
Brugia malayi neuropeptide F receptor 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0066
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0264 0.1327
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0026 0.0031
Echinococcus granulosus sex peptide receptor 0.0015 0.0036 0.0043
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0912 0.4739
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0066 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0238 0.0971
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0036 0.0043
Toxoplasma gondii target of rapamycin (TOR), putative 0.0017 0.0052 0.007
Loa Loa (eye worm) hypothetical protein 0.119 0.8421 0.8421
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0237 0.0283
Onchocerca volvulus 0.01 0.0642 0.0738
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0113 0.0731 0.0862
Brugia malayi Melatonin receptor type 1A 0.0015 0.0036 0.0011
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0237 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0345 0.0383
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.096
Schistosoma mansoni hypothetical protein 0.0016 0.0043 0.002
Giardia lamblia Sgs1 DNA helicase, putative 0.0017 0.0047 0.0022
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0186 0.1254 0.1499
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0127 0.0833 0.0961
Trypanosoma brucei unspecified product 0.0014 0.0025 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0019
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0017 0.0052 0.0062
Echinococcus granulosus dna polymerase eta 0.002 0.0069 0.0082
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0345 0.0413
Schistosoma mansoni adenoreceptor 0.0015 0.0036 0.0011
Brugia malayi Associated with TFs and helicases family protein 0.0019 0.0066 0.0048
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0186 0.1254 0.1463
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0648 0.0774
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Mycobacterium ulcerans lipase LipD 0.0043 0.0238 0.0971
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0036 0.0043
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0036 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0172 0.0542
Brugia malayi phosphofructokinase 0.0127 0.0833 0.0961
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0172 0.1851
Trichomonas vaginalis Heterochromatin protein, putative 0.0019 0.0066 0.0197
Loa Loa (eye worm) glutaminase 0.0319 0.2204 0.2204
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0124 0.0813 0.2634
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0089 0.0792
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0036 0.0043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Schistosoma mansoni hypothetical protein 0.008 0.0498 0.0566
Trichomonas vaginalis chromobox protein, putative 0.0019 0.0066 0.0197
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0186 0.1254 0.1499
Mycobacterium leprae Probable lipase LipE 0.0043 0.0238 0.2387
Echinococcus granulosus dna polymerase kappa 0.002 0.0069 0.0082
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0322 0.0384
Loa Loa (eye worm) ACC-1 protein 0.0186 0.1254 0.1254
Echinococcus granulosus jumonji domain containing protein 0.0069 0.0421 0.0504
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0015 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0052 0.03 0.03
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0186 0.1254 0.1472
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0026 0.0072
Brugia malayi PHD-finger family protein 0.0044 0.0243 0.0258
Loa Loa (eye worm) hypothetical protein 0.01 0.0642 0.0642
Brugia malayi M-phase phosphoprotein, mpp8 0.0019 0.0066 0.0048
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0077 0.0092
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0036 0.0043
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0289 0.0315
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0036 0.0011
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0648 0.3243
Giardia lamblia hypothetical protein 0.0124 0.0813 0.1184
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0124 0.0813 0.0937
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0042 0.0019
Trypanosoma brucei ISWI complex protein 0.0026 0.0114 0.0128
Brugia malayi Bloom's syndrome protein homolog 0.0017 0.0047 0.0024
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) heterochromatin protein 1 0.0119 0.0776 0.0776
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0124 0.0813 0.0972
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0047 0.0024
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0124 0.0813 0.0944
Brugia malayi exodeoxyribonuclease III family protein 0.0015 0.0032 0.0007
Schistosoma mansoni bromodomain containing protein 0.011 0.071 0.0819
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0086 0.0539 0.0611
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.01 0.0642 0.0642
Onchocerca volvulus 0.0186 0.1254 0.1472
Echinococcus granulosus neuropeptide s receptor 0.0015 0.0036 0.0043
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0036 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0124 0.0813 0.0937
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0099 0.0087
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0186 0.1254 0.1499
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0186 0.1254 0.1463
Echinococcus granulosus bloom syndrome protein 0.0017 0.0047 0.0056
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0346 0.0383
Onchocerca volvulus 0.0049 0.0277 0.03
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0113 0.0731 0.0839
Loa Loa (eye worm) hypothetical protein 0.0043 0.0238 0.0238
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0126 0.015
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0264 0.1093
Echinococcus granulosus fmrfamide receptor 0.0015 0.0036 0.0043
Brugia malayi SET domain containing protein 0.0021 0.0078 0.0062
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1943 0.6318
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0835 0.5884 0.6978
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0089 0.0286
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.199 0.6473
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0186 0.1254 0.1463
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Schistosoma mansoni hypothetical protein 0.0035 0.0179 0.0183
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.004 0.0214 0.0225
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0127 0.0833 0.419
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0042 0.0042
Trichomonas vaginalis DNA helicase recq1, putative 0.0017 0.0047 0.0133
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0238 0.0757
Trypanosoma brucei unspecified product 0.002 0.0069 0.0075
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Brugia malayi PHD-finger family protein 0.0021 0.0079 0.0062
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0172 0.0212
Brugia malayi Pre-SET motif family protein 0.0202 0.1367 0.1597
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0066
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0165 0.0806
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0264 0.1242
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0165 0.0806
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0026 0.0072
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0124 0.0813 0.0944
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0026 0.0072
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0036 0.0011
Brugia malayi hypothetical protein 0.0086 0.0539 0.0611
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Schistosoma mansoni vesicular acetylcholine transporter 0.1182 0.8365 1
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0036 0.0036
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0186 0.1254 0.1463
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0036 0.0011
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0138 0.0165
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0036 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0381 0.0425
Trichomonas vaginalis glucosylceramidase, putative 0.044 0.3071 1
Brugia malayi hypothetical protein 0.0086 0.0539 0.0611
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0197
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0124 0.0813 1
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0403 0.1295
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0113 0.0731 0.0845
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0069 0.0069
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0186 0.1254 0.1463
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0346 0.1468
Leishmania major cAMP-specific phosphodiesterase, putative 0.0124 0.0813 0.0937
Schistosoma mansoni hypothetical protein 0.0015 0.0036 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0237 0.0753
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0831 0.5862 0.7007
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0026 0.0031
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0036 0.0036
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0124 0.0813 0.2634
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0186 0.1254 0.1254
Trypanosoma cruzi target of rapamycin kinase 3 0.0017 0.0052 0.0031
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0075 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0305 0.2101 0.6836
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0099 0.0086
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0264 0.1093
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0264 0.0842
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0238 0.1187
Schistosoma mansoni DNA helicase recq5 0.0017 0.0047 0.0024
Echinococcus multilocularis protein dispatched 1 0.0049 0.028 0.0335
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Brugia malayi beta-lactamase family protein 0.0043 0.0238 0.0252
Echinococcus granulosus neuropeptide receptor 0.0015 0.0036 0.0043
Echinococcus multilocularis fetal alzheimer antigen, falz 0.004 0.0214 0.0256
Onchocerca volvulus 0.0015 0.0036 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0124 0.0813 0.0972
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0124 0.0813 0.0972
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0124 0.0813 0.0937
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0069 0.0194
Leishmania major DNA polymerase kappa, putative 0.002 0.0069 0.005
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0124 0.0813 0.0972
Schistosoma mansoni neurotransmitter gated ion channel 0.0086 0.0539 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0092 0.0281
Trypanosoma cruzi ISWI complex protein 0.0026 0.0114 0.0104
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0075
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0322 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0036 0.0011
Schistosoma mansoni nAChR subunit 0.0186 0.1254 0.1472
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0042 0.0055
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0036 0.0011
Echinococcus multilocularis expressed conserved protein 0.0095 0.0604 0.0722
Onchocerca volvulus 0.0186 0.1254 0.1472
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Schistosoma mansoni hypothetical protein 0.008 0.0498 0.0566
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0066 0.0208
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0346 0.0414
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0047 0.0024
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0066 0.0197
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0069 0.005
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0036 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0264 0.1093
Toxoplasma gondii ABC1 family protein 0.0043 0.0238 0.035
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.0101 0.0101
Onchocerca volvulus 0.0015 0.0036 0.0011
Echinococcus multilocularis bloom syndrome protein 0.0017 0.0047 0.0056
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0138 0.0138
Loa Loa (eye worm) phosphofructokinase 0.0127 0.0833 0.0833
Brugia malayi Dopamine receptor protein 2 0.0015 0.0036 0.0011
Echinococcus granulosus Chromobox protein 3 0.0019 0.0066 0.0079
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0535 0.3746 0.4431
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0939 0.663 0.7926
Schistosoma mansoni acetylcholine receptor-related 0.0086 0.0539 0.0615
Plasmodium falciparum phd finger protein, putative 0.005 0.0282 0.3253
Toxoplasma gondii PHD-finger domain-containing protein 0.005 0.0282 0.0417
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0017 0.0052 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1943 0.6318
Schistosoma mansoni cpg binding protein 0.0034 0.0173 0.0176
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0042 0.0019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0322 0.0384
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Brugia malayi Serotonin receptor 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0042
Echinococcus granulosus peregrin 0.0054 0.0311 0.0372
Schistosoma mansoni zinc finger protein 0.0026 0.0114 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.199 0.6473
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0049 0.0277 0.03
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0238 0.0253
Echinococcus multilocularis glycine receptor subunit beta 0.0186 0.1254 0.1499
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0036 0.0043
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0047 0.0062
Entamoeba histolytica recQ family helicase, putative 0.0017 0.0047 0.0106
Loa Loa (eye worm) LGC-31 protein 0.0186 0.1254 0.1254
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0648 0.074
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0015 0.0032 0.0072
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0186 0.1254 0.1463
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0238 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0089 0.0125
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Mycobacterium ulcerans beta-lactamase 0.0043 0.0238 0.0971
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Plasmodium vivax SET domain protein, putative 0.0029 0.0138 0.1417
Trichomonas vaginalis glucosylceramidase, putative 0.0305 0.2101 0.6836
Brugia malayi larval opioid receptor 0.0015 0.0036 0.0011
Schistosoma mansoni opsin-like receptor 0.0015 0.0036 0.0011
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.01 0.0642 0.0738
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0186 0.1254 0.1463
Echinococcus granulosus microtubule associated protein 2 0.0667 0.4686 0.5601
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0346 0.0381
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0026 0.0031
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0015 0.0032 0.0007
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0069 0.0051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1943 0.6318
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0191 0.0197
Trichomonas vaginalis chromobox protein, putative 0.0119 0.0776 0.2511
Schistosoma mansoni lozenge 0.0043 0.0236 0.0252
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0026 0.0024
Brugia malayi Valyl-tRNA synthetase 0.0019 0.0066 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0124 0.0813 0.0937
Echinococcus granulosus phd:f box containing protein 0.0016 0.0042 0.005
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0086 0.0539 0.0645
Onchocerca volvulus 0.0043 0.0238 0.0253
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0026 0.0024
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0357 0.0427
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0186 0.1254 0.1499
Brugia malayi ERG2 and Sigma1 receptor like protein 0.119 0.8421 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.008 0.0501 0.0569
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Echinococcus granulosus glycine receptor subunit beta 0.0186 0.1254 0.1499
Echinococcus multilocularis PHD finger protein rhinoceros 0.005 0.0282 0.0337
Echinococcus granulosus chromobox protein 1 0.0119 0.0776 0.0927
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0047 0.0062
Loa Loa (eye worm) hypothetical protein 0.0124 0.0813 0.0813
Echinococcus granulosus glycine receptor subunit beta 0.0186 0.1254 0.1499
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0036 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0197
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0163 0.109 0.1303
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0124 0.0813 0.096
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0019 0.0066 0.0507
Schistosoma mansoni hypothetical protein 0.0037 0.0191 0.0197
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0069 0.005
Echinococcus multilocularis cpg binding protein 0.0034 0.0173 0.0207
Entamoeba histolytica hypothetical protein 0.0037 0.0191 0.0858
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.0957 0.1144
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0042 0.0019
Loa Loa (eye worm) hypothetical protein 0.01 0.0642 0.0642
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0264 0.2688
Schistosoma mansoni chromobox protein 0.0119 0.0776 0.0898
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0072 0.0439 0.0495
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0153 0.1021 0.1021
Trichomonas vaginalis glutaminase, putative 0.0319 0.2204 0.7171
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0172 0.1851
Echinococcus multilocularis nAChR subunit 0.0186 0.1254 0.1499
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0346 0.1468
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus cpg binding protein 0.0034 0.0173 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Schistosoma mansoni ap endonuclease 0.0015 0.0032 0.0007
Schistosoma mansoni hypothetical protein 0.0026 0.0114 0.0105
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0912 0.4066
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0186 0.1254 0.1463
Echinococcus granulosus methyl CpG binding domain protein 2 0.0029 0.0135 0.0161
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0036 0.0043
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0026 0.0031
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Loa Loa (eye worm) hypothetical protein 0.0939 0.663 0.663
Onchocerca volvulus 0.0015 0.0036 0.0011
Echinococcus granulosus tumor protein p63 0.0346 0.24 0.2869
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0813 0.2634
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0124 0.0813 0.0944
Plasmodium vivax hypothetical protein, conserved 0.005 0.0282 0.3253
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0036 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0153 0.1021 0.1021
Loa Loa (eye worm) glutaminase 2 0.0319 0.2204 0.2204
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0036 0.0043
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0015 0.0032 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0238 0.2686
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0036 0.0011
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0017 0.0052 0.0134
Brugia malayi GnHR receptor homolog 0.0015 0.0036 0.0011
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0036 0.0043
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0047 0.0264 0.0264
Brugia malayi G-protein coupled receptor 0.0015 0.0036 0.0011
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.008 0.0498 0.0596
Loa Loa (eye worm) hypothetical protein 0.0021 0.0079 0.0079
Plasmodium vivax JmjC domain containing protein 0.0016 0.0042 0.0198
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0029 0.0135 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Echinococcus multilocularis peregrin 0.0054 0.0311 0.0372
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0124 0.0813 0.0972
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0032 0.0007
Brugia malayi hypothetical protein 0.0019 0.0066 0.0048
Loa Loa (eye worm) GABA receptor subunit 0.01 0.0642 0.0642
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0017 0.0047 0.0056
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0026 0.0072
Echinococcus multilocularis dnaJ subfamily B 0.0419 0.2921 0.3491
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0036 0.0043
Echinococcus granulosus nAChR subunit 0.01 0.0642 0.0768
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.005 0.0282 0.0307
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Echinococcus multilocularis glycine receptor subunit beta 0.0186 0.1254 0.1499
Schistosoma mansoni opsin-like receptor 0.0015 0.0036 0.0011
Schistosoma mansoni biogenic amine receptor 0.0015 0.0036 0.0011
Echinococcus granulosus hypothetical protein 0.0015 0.0036 0.0043
Toxoplasma gondii PHD-finger domain-containing protein 0.0016 0.0043 0.0057
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0104 0.0666 0.0796
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0186 0.1254 0.1499
Loa Loa (eye worm) hypothetical protein 0.01 0.0642 0.0642
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0114 0.0353
Trichomonas vaginalis glucosylceramidase, putative 0.044 0.3071 1
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0186 0.1254 0.1499
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus neuropeptide receptor 0.0015 0.0036 0.0043
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0017 0.0052 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0036 0.0011
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.1367 0.1367
Schistosoma mansoni hypothetical protein 0.0042 0.0225 0.0239
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0395 0.0395
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0172 0.0542
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus multilocularis serotonin receptor 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0043 0.0238 0.0238
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0019 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.005 0.0282 0.0282
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0101 0.009
Brugia malayi chromobox protein homolog 3 0.0067 0.0403 0.0448
Brugia malayi Cation transporter family protein 0.0186 0.1254 0.1463
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0036 0.0036
Brugia malayi jmjC domain containing protein 0.0163 0.109 0.1267
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0197
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0186 0.1254 0.1254
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0172 0.0542
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0042 0.0019
Trichomonas vaginalis DNA helicase recq, putative 0.0017 0.0047 0.0133
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0069 0.005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0066
Loa Loa (eye worm) acetylcholine receptor protein 0.0086 0.0539 0.0539
Loa Loa (eye worm) hypothetical protein 0.0345 0.2391 0.2391
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.4686 0.5587
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0186 0.1254 0.1254
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0165 0.0806
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0392 0.0439
Entamoeba histolytica phosphofructokinase, putative 0.0127 0.0833 0.4208
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0345 0.0413
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0186 0.1254 0.1499
Echinococcus multilocularis vesicular acetylcholine transporter 0.1182 0.8365 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0036 0.0043
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0066 0.0208
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0124 0.0813 0.0813
Schistosoma mansoni hypothetical protein 0.0487 0.3401 0.4047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0019
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.191 1
Trichomonas vaginalis hypothetical protein 0.0019 0.0066 0.0197
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0036 0.0043
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0047 0.0264 0.0264
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0036 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0086 0.0539 0.0611
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0135 0.013
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0186 0.1254 0.1254
Entamoeba histolytica hypothetical protein 0.0024 0.0099 0.0377
Schistosoma mansoni nAChR subunit 0.0086 0.0539 0.0615
Trichomonas vaginalis esterase, putative 0.0043 0.0238 0.0757
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0172 0.0251
Loa Loa (eye worm) hypothetical protein 0.0043 0.0238 0.0238
Echinococcus granulosus g protein coupled receptor 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0191 0.0228
Echinococcus multilocularis zinc finger protein 0.0035 0.0178 0.0212
Loa Loa (eye worm) hypothetical protein 0.0086 0.0539 0.0539
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0114 0.0353
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0019
Echinococcus multilocularis transcription factor Dp 1 0.0065 0.0393 0.0469
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0186 0.1254 0.1463
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0833 0.2697
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0939 0.663 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0018 0.0056 0.038
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0172 0.0251
Brugia malayi CXXC zinc finger family protein 0.0029 0.0138 0.0132
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0487 0.3401 0.4047
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0042 0.0043
Brugia malayi glutaminase DH11.1 0.0319 0.2204 0.2594
Schistosoma mansoni patched 1 0.0043 0.0237 0.0252
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Loa Loa (eye worm) hypothetical protein 0.0043 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0043 0.0238 0.0238
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0186 0.1254 0.1499
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0238 0.1187
Onchocerca volvulus 0.0015 0.0036 0.0011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0036 0.0011
Schistosoma mansoni hypothetical protein 0.008 0.0498 0.0566
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0238 0.2387
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0036 0.0043
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0036 0.0036
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0036 0.0011
Echinococcus granulosus transcription factor Dp 1 0.0065 0.0393 0.0469
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0113 0.0731 0.0731
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0069 0.0051
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0019 0.0066 0.0091
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0036 0.0043
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0036 0.0043
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0036 0.0011
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0069 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Brugia malayi Serotonin receptor 0.0015 0.0036 0.0011
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0365 0.0436
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0036 0.0011
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.0036 0.0036
Echinococcus granulosus PHD finger protein rhinoceros 0.005 0.0282 0.0337
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0036 0.0043
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0124 0.0813 0.0972
Schistosoma mansoni jumonji domain containing protein 0.0129 0.0851 0.0989
Echinococcus multilocularis nAChR subunit 0.01 0.0642 0.0768
Schistosoma mansoni neuropeptide receptor 0.0015 0.0036 0.0011
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.1182 0.8365 0.8365
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0197
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.4686 0.5601
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0026 0.0072
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0036 0.0011
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0135 0.013
Loa Loa (eye worm) hypothetical protein 0.0186 0.1254 0.1254
Brugia malayi ORL1-like opioid receptor 0.0015 0.0036 0.0011
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.1182 0.8365 1
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0346 0.0383
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0124 0.0813 0.0972
Brugia malayi hypothetical protein 0.0345 0.2391 0.2816
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0017 0.0047 0.0056
Echinococcus granulosus geminin 0.0487 0.3401 0.4066
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0124 0.0813 0.2634
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0238 0.0284
Onchocerca volvulus 0.0015 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Entamoeba histolytica hypothetical protein 0.0037 0.0191 0.0858
Brugia malayi hypothetical protein 0.0015 0.0036 0.0011
Toxoplasma gondii PHD-finger domain-containing protein 0.005 0.0282 0.0417
Onchocerca volvulus 0.01 0.0642 0.0738
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0172 0.0733
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0813 0.2634
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0179
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0052 0.0031
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0043 0.0238 0.0238
Loa Loa (eye worm) RecQ helicase 0.0017 0.0047 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Echinococcus granulosus nAChR subunit 0.0186 0.1254 0.1499
Plasmodium falciparum phosphodiesterase delta, putative 0.0124 0.0813 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0017 0.0052 0.0031
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0186 0.1254 0.1499
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0052 0.0151
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0172 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0066 0.0197
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0237 0.0237
Echinococcus multilocularis chromobox protein 2 0.0019 0.0066 0.0079
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0113 0.0731 0.0874
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0238 0.1187
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0127 0.0833 0.9106
Brugia malayi Dopamine receptor 0.0015 0.0036 0.0011
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.0101 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0124 0.0813 0.0937
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0075
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0124 0.0813 0.0944
Schistosoma mansoni chromobox protein 0.0019 0.0066 0.0048
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.0957 0.1144
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0016 0.0043 0.0045
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0124 0.0813 0.1219
Echinococcus granulosus muscleblind protein 0.0153 0.1021 0.122
Onchocerca volvulus 0.0015 0.0036 0.0011
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0264 0.1242
Echinococcus granulosus 6 phosphofructokinase 0.0127 0.0833 0.0995

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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