Detailed information for compound 846244

Basic information

Technical information
  • TDR Targets ID: 846244
  • Name: 4-(4-ethylpiperazin-1-yl)-6-methoxy-3-phenyls ulfonylquinoline
  • MW: 411.517 | Formula: C22H25N3O3S
  • H donors: 0 H acceptors: 3 LogP: 3.26 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN1CCN(CC1)c1c2cc(OC)ccc2ncc1S(=O)(=O)c1ccccc1
  • InChi: 1S/C22H25N3O3S/c1-3-24-11-13-25(14-12-24)22-19-15-17(28-2)9-10-20(19)23-16-21(22)29(26,27)18-7-5-4-6-8-18/h4-10,15-16H,3,11-14H2,1-2H3
  • InChiKey: ULIFBKPSGDOCSR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-(4-ethylpiperazin-1-yl)-6-methoxy-3-phenylsulfonyl-quinoline
  • 4-(4-ethyl-1-piperazinyl)-6-methoxy-3-phenylsulfonylquinoline

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi jmjC domain containing protein 0.0045 0.0097 0.0104
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.008 0.0256 0.0348
Echinococcus granulosus adenosine kinase 0.0939 0.4175 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.008 0.0256 0.0587
Brugia malayi beta-NAC-like protein 0.0042 0.0085 0.0085
Trypanosoma brucei adenosine transporter 2 0.0044 0.0093 0.015
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0044 0.0093 0.015
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.3693 0.8473
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0254 0.1049 0.1014
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.0548 0.2393 1
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0241 0.0553
Loa Loa (eye worm) RNA binding protein 0.0076 0.0241 0.0361
Toxoplasma gondii kinase, pfkB family protein 0.0107 0.038 0.0843
Brugia malayi Nuclear hormone receptor family member nhr-19 0.008 0.0256 0.0348
Trypanosoma brucei Heat shock protein 83, putative 0.0055 0.0145 0.0274
Brugia malayi hypothetical protein 0.0254 0.1049 0.1568
Brugia malayi Nuclear hormone receptor family member nhr-25 0.008 0.0256 0.0348
Trypanosoma brucei nucleoside transporter 1, putative 0.0044 0.0093 0.015
Trypanosoma brucei unspecified product 0.0044 0.0093 0.015
Trichomonas vaginalis endoplasmin, putative 0.004 0.0075 0.0037
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.011 0.0393 0.056
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0042 0.0084 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0825 0.079
Onchocerca volvulus 0.0058 0.0155 0.0153
Brugia malayi nuclear hormone receptor family member nhr-6 0.0038 0.0064 0.0053
Trypanosoma brucei heat shock protein, putative 0.0055 0.0145 0.0274
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0096 0.0156
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0145 0.0363
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0037 0.006 0.0011
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0052 0.0129 0.0236
Loa Loa (eye worm) steroid hormone receptor 0.008 0.0256 0.0383
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0053 0.0072
Schistosoma mansoni heat shock protein 0.0055 0.0145 0.0346
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0064 0.0016
Schistosoma mansoni RAR-like nuclear receptor 0.008 0.0256 0.0612
Loa Loa (eye worm) hypothetical protein 0.0939 0.4175 0.6389
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0825 0.079
Onchocerca volvulus 0.0037 0.0061 0.0012
Toxoplasma gondii nucleoside transporter protein 0.0044 0.0093 0.015
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0191 0.0249
Leishmania major carbonic anhydrase-like protein 0.0296 0.1242 0.2923
Leishmania major heat shock protein, putative 0.0037 0.006 0.007
Trypanosoma brucei adenosine kinase, putative 0.0939 0.4175 1
Entamoeba histolytica nucleoside transporter, putative 0.0254 0.1049 0.4238
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0254 0.1049 0.1014
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1314 0.1281
Loa Loa (eye worm) heat shock protein 75 0.0037 0.006 0.0083
Plasmodium falciparum phd finger protein, putative 0.0035 0.0053 0.0266
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0052 0.0129 1
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0044 0.0006
Echinococcus granulosus chromobox protein 1 0.0084 0.0276 0.0661
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0227 0.0177
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.3693 0.8845
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Brugia malayi Bromodomain containing protein 0.0038 0.0066 0.0056
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Loa Loa (eye worm) hypothetical protein 0.011 0.0393 0.0594
Echinococcus granulosus histone lysine methyltransferase setb 0.0057 0.0151 0.0361
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0084 0.0084
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0052 0.0129 0.0064
Brugia malayi Steroid receptor seven-up type 2 0.008 0.0256 0.0348
Echinococcus multilocularis thyroid hormone receptor alpha 0.008 0.0256 0.0587
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0227 0.0927 0.2128
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0221 0.0507
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.008 0.0256 0.0612
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0044 0.0093 0.0054
Brugia malayi Pre-SET motif family protein 0.0036 0.0057 0.0042
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.0155 0.0371
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0084 0.0084
Trypanosoma brucei adenosine transporter 2 0.0044 0.0093 0.015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.008 0.0256 0.0587
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0276 0.0414
Echinococcus granulosus carbonic anhydrase II 0.0296 0.1242 0.2976
Plasmodium vivax heat shock protein, putative 0.021 0.0849 1
Toxoplasma gondii NAC domain-containing protein 0.0042 0.0085 0.013
Plasmodium vivax heat shock protein 86, putative 0.0055 0.0145 0.1389
Mycobacterium ulcerans heat shock protein 90 0.0052 0.0129 0.0034
Loa Loa (eye worm) hypothetical protein 0.008 0.0256 0.0383
Loa Loa (eye worm) hypothetical protein 0.0037 0.0061 0.0084
Mycobacterium ulcerans carbonic anhydrase 0.0548 0.2393 0.2319
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.1314 0.2006
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0044 0.0093 0.015
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0085 0.013
Trichomonas vaginalis ribokinase, putative 0.0107 0.038 0.0343
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.008 0.0256 0.0612
Echinococcus multilocularis ecdysone induced protein 78C 0.008 0.0256 0.0587
Echinococcus multilocularis carbonic anhydrase 0.011 0.0393 0.0903
Onchocerca volvulus 0.0038 0.0064 0.0016
Onchocerca volvulus 0.008 0.0256 0.0304
Brugia malayi TAR-binding protein 0.0076 0.0241 0.0326
Loa Loa (eye worm) hypothetical protein 0.008 0.0256 0.0383
Plasmodium vivax heat shock protein 90, putative 0.0037 0.006 0.0353
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0044 0.0093 0.0054
Loa Loa (eye worm) hypothetical protein 0.1418 0.6359 0.9737
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0038 0.0064 0.0053
Echinococcus multilocularis transcription factor btf3 0.0042 0.0085 0.0194
Trypanosoma brucei purine nucleoside transporter 0.0044 0.0093 0.015
Toxoplasma gondii kinase, pfkB family protein 0.0939 0.4175 1
Schistosoma mansoni lipoxygenase 0.0119 0.0433 0.1036
Trypanosoma brucei purine nucleoside transporter 0.0044 0.0093 0.015
Schistosoma mansoni jumonji domain containing protein 0.0092 0.031 0.0743
Trypanosoma brucei heat shock protein 84, putative 0.0037 0.006 0.007
Leishmania major adenosine kinase, putative 0.0939 0.4175 1
Echinococcus granulosus peregrin 0.0038 0.0066 0.0158
Loa Loa (eye worm) hypothetical protein 0.0052 0.0127 0.0186
Giardia lamblia Heat shock protein HSP 90-alpha 0.0055 0.0145 0.0922
Loa Loa (eye worm) heat shock protein 90 0.0055 0.0145 0.0213
Trichomonas vaginalis heat shock protein, putative 0.0055 0.0145 0.0106
Trichomonas vaginalis set domain proteins, putative 0.0286 0.1197 0.1162
Loa Loa (eye worm) carbonic anhydrase 3 0.0296 0.1242 0.1895
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.009 0.0207
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.0759 0.3354 0.3817
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0085 0.0046
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0227 0.0472
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0107 0.038 0.0911
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.1038 0.1583
Loa Loa (eye worm) nuclear receptor nhr-7B 0.1456 0.653 1
Leishmania major nucleoside transporter 1, putative 0.0044 0.0093 0.015
Mycobacterium leprae Probable adenosine kinase adk 0.0107 0.038 0.1319
Brugia malayi hypothetical protein 0.0535 0.2331 0.3541
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0053 0.0121
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0227 0.0472
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Loa Loa (eye worm) nuclear hormone receptor 0.0038 0.0064 0.0089
Echinococcus granulosus microtubule associated protein 2 0.0833 0.3693 0.8845
Echinococcus multilocularis adenosine kinase 0.0939 0.4175 0.9579
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0876 0.084
Trypanosoma brucei heat shock protein, putative 0.0055 0.0145 0.0274
Brugia malayi hypothetical protein 0.0042 0.0084 0.0084
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0145 0.0363
Trypanosoma brucei adenosine transporter 2, putative 0.0044 0.0093 0.015
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0044 0.0093 0.0054
Schistosoma mansoni hypothetical protein 0.035 0.1489 0.3567
Trypanosoma brucei adenosine transporter 2, putative 0.0044 0.0093 0.015
Entamoeba histolytica hypothetical protein 0.0042 0.0085 0.0107
Entamoeba histolytica hypothetical protein 0.0042 0.0084 0.0102
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0145 0.0274
Schistosoma mansoni ribokinase 0.0107 0.038 0.0911
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0119 0.0433 0.1036
Leishmania major nucleobase transporter 0.0044 0.0093 0.015
Schistosoma mansoni adenosine kinase 0.0939 0.4175 1
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0047 0.0108 0.0259
Brugia malayi tailless protein 0.0038 0.0064 0.0053
Schistosoma mansoni carbonic anhydrase-related 0.011 0.0393 0.0942
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.008 0.0256 0.0612
Onchocerca volvulus 0.0038 0.0064 0.0016
Brugia malayi heat shock protein 90 0.0055 0.0145 0.0177
Brugia malayi nuclear receptor RXR 0.0042 0.0084 0.0084
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.0155 0.0153
Trypanosoma brucei ribokinase, putative 0.0107 0.038 0.0843
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0097 0.0232
Trypanosoma brucei unspecified product 0.0044 0.0093 0.015
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.4358 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0016 0.0037
Trypanosoma cruzi nucleoside transporter-like, putative 0.0044 0.0093 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.008 0.0256 0.0383
Loa Loa (eye worm) hypothetical protein 0.0254 0.1049 0.1598
Schistosoma mansoni nuclear receptor nhr-48 0.0038 0.0064 0.0152
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Plasmodium falciparum basic transcription factor 3b, putative 0.0042 0.0085 0.0657
Trypanosoma brucei heat shock protein, putative 0.0055 0.0145 0.0274
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0124 0.0085
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0064 0.0152
Leishmania major tagatose-6-phosphate kinase-like protein 0.0107 0.038 0.0843
Plasmodium vivax SET domain protein, putative 0.0036 0.0057 0.0313
Schistosoma mansoni lozenge 0.0067 0.0198 0.0475
Brugia malayi nuclear receptor NHR-88 0.0038 0.0064 0.0053
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0155 0.0371
Entamoeba histolytica hypothetical protein 0.0042 0.0084 0.0102
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0016 0.0039
Schistosoma mansoni hypothetical protein 0.0035 0.0053 0.0126
Trypanosoma brucei Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0064 0.0186 0.0373
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0057 0.0151 0.0345
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0096 0.0156
Echinococcus granulosus ribokinase 0.0107 0.038 0.0911
Trypanosoma brucei heat shock protein, putative 0.0055 0.0145 0.0274
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0296 0.1242 0.1866
Loa Loa (eye worm) hypothetical protein 0.0049 0.0117 0.017
Mycobacterium ulcerans integral membrane transporter 0.0064 0.0186 0.0091
Trypanosoma brucei carbonic anhydrase-like protein 0.0296 0.1242 0.2923
Brugia malayi hypothetical protein 0.0042 0.0084 0.0084
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.011 0.0393 0.0594
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0042 0.0084 0.0202
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0241 0.0577
Loa Loa (eye worm) hypothetical protein 0.0535 0.2331 0.3564
Echinococcus granulosus FTZ F1 alpha 0.008 0.0256 0.0612
Trypanosoma cruzi adenosine kinase, putative 0.0939 0.4175 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.0155 0.0355
Trypanosoma brucei heat shock protein, putative 0.0055 0.0145 0.0274
Brugia malayi Nuclear hormone receptor family member nhr-49 0.008 0.0256 0.0348
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1314 0.1281
Loa Loa (eye worm) hypothetical protein 0.0254 0.1049 0.1598
Loa Loa (eye worm) hypothetical protein 0.0148 0.0567 0.086
Loa Loa (eye worm) hypothetical protein 0.008 0.0256 0.0383
Brugia malayi ecdysteroid receptor 0.008 0.0256 0.0348
Schistosoma mansoni protein kinase 0.0044 0.0093 0.0223
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0296 0.1242 0.2976
Brugia malayi nuclear receptor NHR-67 0.0038 0.0064 0.0053
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0296 0.1242 0.1866
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.008 0.0256 0.0587
Onchocerca volvulus 0.0535 0.2331 0.3417
Mycobacterium tuberculosis Adenosine kinase 0.0107 0.038 0.0356
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0876 0.084
Entamoeba histolytica transcription factor BTF3, putative 0.0042 0.0085 0.0107
Brugia malayi PHD-finger family protein 0.0035 0.0053 0.0036
Loa Loa (eye worm) hypothetical protein 0.008 0.0256 0.0383
Brugia malayi Inositol-1 0.0045 0.0096 0.0102
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Leishmania major nucleoside transporter 1, putative 0.0044 0.0093 0.015
Trichomonas vaginalis ribokinase, putative 0.0107 0.038 0.0343
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0151 0.0361
Echinococcus multilocularis endoplasmin 0.0052 0.0129 0.0296
Leishmania major basic transcription factor 3a, putative 0.0042 0.0085 0.013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0057 0.0136
Brugia malayi Nuclear hormone receptor family member nhr-31 0.008 0.0256 0.0348
Trypanosoma cruzi heat shock protein 90, putative 0.0055 0.0145 0.0274
Trypanosoma cruzi heat shock protein, putative 0.0037 0.006 0.007
Brugia malayi Heterochromatin protein 1 0.0084 0.0276 0.0379
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.008 0.0256 0.0612
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0254 0.1049 0.1493
Echinococcus granulosus nuclear receptor nhr 48 0.0038 0.0064 0.0152
Onchocerca volvulus Bile acid receptor homolog 0.008 0.0256 0.0304
Echinococcus multilocularis FTZ F1 alpha 0.008 0.0256 0.0587
Echinococcus granulosus heat shock protein 90 0.0047 0.0108 0.0259
Echinococcus multilocularis chromobox protein 1 0.0084 0.0276 0.0633
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0084 0.0202
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Giardia lamblia Grp94/Hsp90 0.0052 0.0129 0.0766
Leishmania major adenosine kinase-like protein 0.0107 0.038 0.0843
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0037 0.006 0.0137
Loa Loa (eye worm) hypothetical protein 0.011 0.0393 0.0594
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0155 0.0371
Loa Loa (eye worm) hypothetical protein 0.0085 0.0282 0.0423
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0145 0.0274
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.008 0.0256 0.0383
Loa Loa (eye worm) hypothetical protein 0.008 0.0256 0.0383
Giardia lamblia Heat shock protein HSP 90-alpha 0.0047 0.0108 0.0556
Leishmania major adenosine kinase-like protein 0.0107 0.038 0.0843
Echinococcus granulosus heat shock protein 90 0.0055 0.0145 0.0346
Plasmodium falciparum heat shock protein 90 0.0055 0.0145 0.1389
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0296 0.1242 0.2923
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.011 0.0393 0.056
Trypanosoma brucei heat shock protein, putative 0.0055 0.0145 0.0274
Loa Loa (eye worm) DR-78 0.0038 0.0064 0.0089
Echinococcus granulosus carbonic anhydrase 0.011 0.0393 0.0942
Loa Loa (eye worm) hypothetical protein 0.011 0.0393 0.0594
Schistosoma mansoni heat shock protein 0.0055 0.0145 0.0346
Entamoeba histolytica carbonic anhydrase, putative 0.0548 0.2393 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0038 0.0064 0.0152
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0191 0.0458
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.0155
Brugia malayi hypothetical protein 0.0044 0.0093 0.0098
Plasmodium falciparum endoplasmin, putative 0.004 0.0075 0.0542
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0241 0.0361
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0044 0.0093 0.015
Loa Loa (eye worm) inositol-1 0.0045 0.0096 0.0138
Echinococcus multilocularis chromobox protein 1 0.0084 0.0276 0.0633
Loa Loa (eye worm) hypothetical protein 0.0046 0.0104 0.015
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0227 0.0543
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0044 0.0093 0.0054
Echinococcus multilocularis nuclear receptor nhr 48 0.0038 0.0064 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.2216 1 1
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0037 0.006 0.0143
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.008 0.0256 0.0348
Schistosoma mansoni zinc finger protein 0.0038 0.0064 0.0152
Echinococcus granulosus heat shock protein 0.0055 0.0145 0.0346
Mycobacterium tuberculosis Ribokinase RbsK 0.0107 0.038 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0107 0.0069
Loa Loa (eye worm) runx1 0.0067 0.0198 0.0295
Schistosoma mansoni thyroid hormone receptor 0.008 0.0256 0.0612
Echinococcus multilocularis carbonic anhydrase II 0.0296 0.1242 0.285
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.008 0.0256 0.0612
Loa Loa (eye worm) MBCTL1 0.0066 0.0191 0.0284
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0042 0.0084 0.0202
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0044 0.0093 0.015
Schistosoma mansoni thyroid hormone receptor 0.008 0.0256 0.0612
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0044 0.0006
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0057 0.0062
Brugia malayi hypothetical protein 0.0038 0.0064 0.0053
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0227 0.0543
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.011 0.0393 0.056
Brugia malayi hypothetical protein 0.0038 0.0064 0.0053
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0064 0.0016
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0085 0.013
Plasmodium falciparum heat shock protein 90, putative 0.0032 0.0039 0.0096
Echinococcus multilocularis ribokinase 0.0107 0.038 0.0872
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.0155 0.0371
Toxoplasma gondii heat shock protein 90, putative 0.0055 0.0145 0.0274
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0064 0.0152
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0191 0.0458
Toxoplasma gondii nucleoside transporter protein 0.0044 0.0093 0.015
Schistosoma mansoni endoplasmin 0.0055 0.0145 0.0346
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0044 0.0093 0.015
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0276 0.0238
Brugia malayi nuclear receptor NHR-88 0.008 0.0256 0.0348
Trypanosoma cruzi nucleoside transporter 1, putative 0.0044 0.0093 0.015
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Loa Loa (eye worm) ICD-1 protein 0.0042 0.0085 0.0121
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0467 0.202 0.2264
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0042 0.0084 0.0193
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0053 0.0052
Echinococcus multilocularis peregrin 0.0038 0.0066 0.0151
Toxoplasma gondii nucleoside transporter protein 0.0044 0.0093 0.015
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0097 0.0232
Brugia malayi nuclear receptor RXR 0.0038 0.0064 0.0053
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0254 0.1049 0.2406
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0051 0.0121
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Loa Loa (eye worm) hypothetical protein 0.0042 0.0084 0.012
Trypanosoma brucei adenosine transporter 2, putative 0.0044 0.0093 0.015
Schistosoma mansoni bromodomain containing protein 0.0076 0.0241 0.0577
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Loa Loa (eye worm) endoplasmin 0.0055 0.0145 0.0213
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0096 0.0156
Onchocerca volvulus 0.0404 0.1734 0.2521
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0276 0.0238
Echinococcus granulosus nuclear receptor 2DBD gamma 0.008 0.0256 0.0612
Schistosoma mansoni chromobox protein 0.0084 0.0276 0.0661
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.009 0.0216
Loa Loa (eye worm) hypothetical protein 0.0148 0.0567 0.086
Chlamydia trachomatis sulfate transporter 0.0064 0.0186 0.5
Entamoeba histolytica ribokinase, putative 0.0107 0.038 0.1373
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.008 0.0256 0.0612
Plasmodium falciparum inorganic anion exchanger, inorganic anion antiporter 0.0064 0.0186 0.1891
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0418 0.1001
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.0108 0.0186
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.0825 0.1158
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0116 0.0277
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0064 0.0186 0.0373
Brugia malayi Adenosine kinase-like 0.0939 0.4175 0.6376
Brugia malayi mbt repeat family protein 0.0058 0.0155 0.0193
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0038 0.0064 0.0152
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0107 0.038 0.0287
Loa Loa (eye worm) hypothetical protein 0.0042 0.0084 0.012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.008 0.0256 0.0383
Loa Loa (eye worm) hypothetical protein 0.003 0.0031 0.0039
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0096 0.0153
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0096 0.0057
Treponema pallidum heat shock protein 90 0.0052 0.0129 0.5
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Brugia malayi hypothetical protein 0.003 0.0031 0.0003
Schistosoma mansoni Tr4/Tr2 (homologue) 0.008 0.0256 0.0612
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0191 0.0458
Schistosoma mansoni lipoxygenase 0.0083 0.027 0.0647
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0129 0.0091
Schistosoma mansoni retinoic acid receptor RXR 0.008 0.0256 0.0612
Onchocerca volvulus Protein ultraspiracle homolog 0.008 0.0256 0.0304
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0053 0.0126
Loa Loa (eye worm) hypothetical protein 0.0107 0.038 0.0574
Loa Loa (eye worm) hypothetical protein 0.0042 0.0084 0.012
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0124 0.0106
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0072
Plasmodium falciparum carbonic anhydrase 0.011 0.0393 0.4433
Echinococcus multilocularis carbonic anhydrase 0.011 0.0393 0.0903
Brugia malayi chromobox protein homolog 3 0.0047 0.0107 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.038 0.0343
Echinococcus granulosus carbonic anhydrase 0.011 0.0393 0.0942
Trypanosoma cruzi nucleoside transporter-like, putative 0.0044 0.0093 0.015
Brugia malayi jmjC domain containing protein 0.0115 0.0418 0.0598
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0087 0.0199
Schistosoma mansoni adenosine kinase 0.0939 0.4175 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0084 0.012
Brugia malayi nuclear hormone receptor 0.1456 0.653 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.008 0.0256 0.0383
Plasmodium vivax endoplasmin, putative 0.0055 0.0145 0.1389
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0227 0.0132
Schistosoma mansoni nuclear receptor 0.0038 0.0064 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-40 0.008 0.0256 0.0348
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0064 0.0053
Plasmodium falciparum heat shock protein 90, putative 0.021 0.0849 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0221 0.0529
Onchocerca volvulus Ribokinase homolog 0.0107 0.038 0.0491
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0116 0.0265
Schistosoma mansoni carbonic anhydrase-related 0.011 0.0393 0.0942
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.011 0.0393 0.056
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0107 0.0082
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.008 0.0256 0.0383
Echinococcus multilocularis heat shock protein 90 0.0055 0.0145 0.0332
Onchocerca volvulus 0.0832 0.3687 0.5448
Echinococcus multilocularis heat shock protein 0.0055 0.0145 0.0332
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0064 0.0146
Entamoeba histolytica fructokinase, putative 0.0107 0.038 0.1373
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0254 0.1049 0.2512
Brugia malayi Nuclear hormone receptor family member nhr-3 0.008 0.0256 0.0348
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0145 0.0274
Trypanosoma brucei heat shock protein, putative 0.0055 0.0145 0.0274
Echinococcus granulosus chromobox protein 1 0.0084 0.0276 0.0661
Brugia malayi Nuclear hormone receptor family member nhr-1 0.008 0.0256 0.0348
Onchocerca volvulus Putative sulfate transporter 0.0404 0.1734 0.2521
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0057 0.013
Onchocerca volvulus Putative pyridoxal kinase 0.0107 0.038 0.0491
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.008 0.0256 0.0612
Toxoplasma gondii heat shock protein 75, putative 0.0037 0.006 0.007
Trypanosoma brucei adenosine transporter 2, putative 0.0044 0.0093 0.015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0191 0.0284
Echinococcus granulosus transcription factor btf3 0.0042 0.0085 0.0203
Brugia malayi Nuclear hormone receptor family member nhr-14 0.008 0.0256 0.0348
Trypanosoma brucei adenosine transporter, putative 0.0044 0.0093 0.015
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0096 0.0219
Schistosoma mansoni hypothetical protein 0.011 0.0393 0.0942
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0241 0.0577
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0241 0.0326
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Schistosoma mansoni carbonic anhydrase 0.0548 0.2393 0.5732
Trypanosoma cruzi nucleobase transporter, putative 0.0044 0.0093 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1314 0.1281
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.0256 0.1059 0.1146
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0296 0.1242 0.2923
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0254 0.1049 0.1493
Brugia malayi Endoplasmin precursor 0.0055 0.0145 0.0177
Brugia malayi hypothetical protein 0.0042 0.0084 0.0084
Schistosoma mansoni retinoid-x-receptor (RXR) 0.008 0.0256 0.0612
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0107 0.038 0.0356
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.0155 0.0355
Loa Loa (eye worm) hypothetical protein 0.008 0.0256 0.0383
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0044 0.0093 0.0054
Leishmania major carbonic anhydrase family protein, putative 0.0548 0.2393 0.57
Trypanosoma cruzi nucleoside transporter 1, putative 0.0044 0.0093 0.015
Brugia malayi Nuclear hormone receptor family member nhr-41 0.008 0.0256 0.0348
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.005 0.0119 0.0286
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0064 0.0146
Entamoeba histolytica hypothetical protein 0.0042 0.0084 0.0102
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0825 0.079
Trichomonas vaginalis heat shock protein, putative 0.004 0.0075 0.0037
Echinococcus multilocularis Protein lozenge 0.0067 0.0198 0.0455
Loa Loa (eye worm) hypothetical protein 0.008 0.0256 0.0383
Schistosoma mansoni chromobox protein 0.0084 0.0276 0.0661
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.008 0.0256 0.0587
Brugia malayi conserved hypotetical protein 0.0038 0.0064 0.0053
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0145 0.0274
Brugia malayi nuclear hormone receptor 0.008 0.0256 0.0348
Echinococcus granulosus nuclear receptor 2DBD gamma 0.008 0.0256 0.0612
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.008 0.0256 0.0587
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0155 0.0371
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0254 0.1049 0.2406
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0296 0.1242 0.1895
Loa Loa (eye worm) hypothetical protein 0.0535 0.2331 0.3564
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0044 0.0093 0.015
Giardia lamblia Ribokinase 0.0107 0.038 0.3288
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0096 0.0057
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0084 0.02
Echinococcus multilocularis heat shock protein 90 0.0047 0.0108 0.0248
Trypanosoma brucei heat shock protein, putative 0.0055 0.0145 0.0274
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0256 0.0348
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0044 0.0093 0.015
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0248
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0064 0.0053
Trypanosoma cruzi nucleobase transporter, putative 0.0044 0.0093 0.015
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0064 0.0186 0.0091
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Loa Loa (eye worm) hypothetical protein 0.008 0.0256 0.0383
Toxoplasma gondii Hsp90 domain-containing protein 0.021 0.0849 0.1973
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0151 0.0361
Schistosoma mansoni carbonic anhydrase-related 0.011 0.0393 0.0942
Brugia malayi nuclear hormone receptor family member odr-7 0.0038 0.0064 0.0053
Schistosoma mansoni inositol monophosphatase 0.0045 0.0096 0.0229
Giardia lamblia Hypothetical protein 0.0254 0.1049 1
Loa Loa (eye worm) hypothetical protein 0.0254 0.1049 0.1598
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0097 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.2216 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0825 0.079
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0064 0.0152
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.021 0.0848 0.1945
Toxoplasma gondii hypothetical protein 0.011 0.0393 0.0875
Leishmania major putative PfkB family sugar kinase 0.0107 0.038 0.0843
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0145 0.0274
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0241 0.0361
Brugia malayi Bromodomain containing protein 0.0091 0.0305 0.0424
Brugia malayi Nuclear hormone receptor family member nhr-19 0.008 0.0256 0.0348
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0064 0.0152
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0227 0.0927 0.2221
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0825 0.079
Onchocerca volvulus Huntingtin homolog 0.0148 0.0567 0.0771
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.011 0.0393 0.056
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0107 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0825 0.079
Brugia malayi orphan nuclear receptor NR2E1 0.0038 0.0064 0.0053
Loa Loa (eye worm) hypothetical protein 0.0057 0.0151 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0085 0.0046
Leishmania major nucleobase transporter 0.0044 0.0093 0.015
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0224 0.0334
Brugia malayi RNA binding protein 0.0076 0.0241 0.0326
Trypanosoma brucei transcription factor BTF3, putative 0.0042 0.0085 0.013
Schistosoma mansoni coup transcription factor 0.008 0.0256 0.0612
Schistosoma mansoni inositol monophosphatase 0.0045 0.0096 0.0229
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0108 0.0069
Echinococcus granulosus carbonic anhydrase 0.011 0.0393 0.0942
Trichomonas vaginalis ribokinase, putative 0.0107 0.038 0.0343
Toxoplasma gondii inorganic anion transporter, sulfate permease (SulP) family protein 0.0064 0.0186 0.0373
Schistosoma mansoni heat shock protein 0.0037 0.006 0.0143
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0124 0.0085
Brugia malayi hypothetical protein 0.0107 0.038 0.054
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0096 0.0057
Trypanosoma brucei adenosine transporter, putative 0.0044 0.0093 0.015
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0107 0.038 0.1373
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.008 0.0256 0.0587
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.008 0.0256 0.0383
Plasmodium vivax sulfate transporter, putative 0.0064 0.0186 0.1891
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0825 0.079
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0053 0.0126
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0064 0.0186 0.0091
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0227 0.0543
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0085 0.0046
Echinococcus granulosus ecdysone induced protein 78C 0.008 0.0256 0.0612
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0227 0.0132
Trypanosoma cruzi adenosine kinase, putative 0.0107 0.038 0.0843
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0016 0.0039
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0119 0.0433 0.0993
Schistosoma mansoni equilibrative nucleoside transporter 0.0044 0.0093 0.0223
Entamoeba histolytica nucleoside transporter, putative 0.0044 0.0093 0.0142
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1314 0.1281
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0241 0.0577
Brugia malayi ecdysone receptor 0.0038 0.0064 0.0053
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0227 0.0132
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0044 0.0093 0.015
Leishmania major ribokinase, putative 0.0107 0.038 0.0843
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0191 0.0439
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0064 0.0152
Mycobacterium ulcerans fructokinase, PfkB 0.0107 0.038 0.0287
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1314 0.1281
Brugia malayi Bromodomain containing protein 0.0046 0.0103 0.0113
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Schistosoma mansoni nuclear receptor 0.0038 0.0064 0.0152
Schistosoma mansoni transcription factor btf3 0.0042 0.0085 0.0203
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0084 0.02
Trypanosoma cruzi Heat shock protein 83, putative 0.0055 0.0145 0.0274
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0096 0.0156
Entamoeba histolytica hypothetical protein 0.0042 0.0084 0.0102
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0097 0.014
Onchocerca volvulus 0.0286 0.1197 0.1715
Brugia malayi photoreceptor-specific nuclear receptor 0.008 0.0256 0.0348
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0084 0.0192
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0096 0.0229
Schistosoma mansoni steroid hormone receptor ad4bp 0.008 0.0256 0.0612
Trypanosoma cruzi adenosine kinase, putative 0.0939 0.4175 1
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0254 0.1049 0.1014
Echinococcus granulosus endoplasmin 0.0052 0.0129 0.0309
Trypanosoma cruzi nucleoside transporter 1, putative 0.0044 0.0093 0.015
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0064 0.0146
Brugia malayi Nucleoside transporter family protein 0.0254 0.1049 0.1568
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0129 0.0091
Entamoeba histolytica nucleoside transporter, putative 0.0044 0.0093 0.0142
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0038 0.0064 0.0146
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0064 0.0186 0.0373
Mycobacterium leprae Probable transmembrane transport protein 0.0467 0.202 0.8392
Schistosoma mansoni nuclear hormone receptor 0.008 0.0256 0.0612
Loa Loa (eye worm) hypothetical protein 0.0044 0.0093 0.0134
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0191 0.0439
Brugia malayi Pre-SET motif family protein 0.0251 0.1038 0.1552
Echinococcus granulosus equilibrative nucleoside transporter 0.0254 0.1049 0.2512
Loa Loa (eye worm) hypothetical protein 0.0058 0.0155 0.0228
Onchocerca volvulus Huntingtin homolog 0.0148 0.0567 0.0771
Loa Loa (eye worm) hypothetical protein 0.0107 0.038 0.0574
Onchocerca volvulus 0.005 0.0119 0.01
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0096 0.0156
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0155 0.0228
Echinococcus granulosus retinoic acid receptor rxr beta a 0.008 0.0256 0.0612
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0227 0.052
Trypanosoma brucei adenosine kinase, putative 0.0939 0.4175 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.008 0.0256 0.0383
Schistosoma mansoni hypothetical protein 0.0042 0.0084 0.02
Echinococcus multilocularis carbonic anhydrase 0.011 0.0393 0.0903
Trypanosoma cruzi ribokinase, putative 0.0107 0.038 0.0843
Schistosoma mansoni carbonic anhydrase 0.011 0.0393 0.0942
Trypanosoma cruzi adenosine kinase, putative 0.0107 0.038 0.0843
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0107 0.038 0.0872
Trypanosoma brucei ribokinase, putative 0.0107 0.038 0.0843
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0089
Brugia malayi mbt repeat family protein 0.0058 0.0155 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-25 0.008 0.0256 0.0348
Schistosoma mansoni hypothetical protein 0.0025 0.0006 0.0014
Trypanosoma cruzi nucleobase transporter, putative 0.0044 0.0093 0.015
Loa Loa (eye worm) nuclear receptor NHR-67 0.0038 0.0064 0.0089
Plasmodium vivax basic transcription factor 3b, putative 0.0042 0.0085 0.0657
Brugia malayi Ribokinase 0.0107 0.038 0.054
Echinococcus granulosus tar DNA binding protein 0.0076 0.0241 0.0577
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0241 0.0577
Trypanosoma brucei nucleoside transporter 1, putative 0.0044 0.0093 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1314 0.1281
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0241 0.0577
Brugia malayi hypothetical protein 0.0148 0.0567 0.0827
Brugia malayi steroid hormone receptor 0.008 0.0256 0.0348
Trypanosoma brucei adenosine transporter 2, putative 0.0044 0.0093 0.015
Leishmania major tagatose-6-phosphate kinase-like protein 0.0107 0.038 0.0843
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0107 0.038 0.1373
Mycobacterium tuberculosis Beta-carbonic anhydrase 0.1924 0.8666 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0418 0.0959
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.008 0.0256 0.0612
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0296 0.1242 0.2976
Leishmania major heat shock protein 83-1 0.0055 0.0145 0.0274
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.1498 0.6722 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.1314 0.1977
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0038 0.0064 0.0152
Onchocerca volvulus 0.0107 0.038 0.0491
Loa Loa (eye worm) hypothetical protein 0.0042 0.0084 0.012
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0254 0.1049 0.1014
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0038 0.0064 0.0152
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0052 0.0129 0.0237
Brugia malayi Hsp90 protein 0.0037 0.006 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0053 0.0266
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0038 0.0064 0.0146
Schistosoma mansoni endoplasmin 0.0055 0.0145 0.0346
Toxoplasma gondii heat shock protein HSP90 0.0055 0.0145 0.0274
Entamoeba histolytica kinase, PfkB family 0.0107 0.038 0.1373
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0108 0.0186

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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