Detailed information for compound 884666

Basic information

Technical information
  • TDR Targets ID: 884666
  • Name: 6-(3-hydroxypropyl)-4,7,8-trimethyl-2-(3-phen ylpropyl)purino[7,8-a]imidazole-1,3-dione
  • MW: 409.481 | Formula: C22H27N5O3
  • H donors: 1 H acceptors: 4 LogP: 3.2 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCCn1c2nc3c(n2c(c1C)C)c(=O)n(c(=O)n3C)CCCc1ccccc1
  • InChi: 1S/C22H27N5O3/c1-15-16(2)27-18-19(23-21(27)25(15)13-8-14-28)24(3)22(30)26(20(18)29)12-7-11-17-9-5-4-6-10-17/h4-6,9-10,28H,7-8,11-14H2,1-3H3
  • InChiKey: WJVBGIYUWUCKFH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-(3-hydroxypropyl)-4,7,8-trimethyl-2-(3-phenylpropyl)purino[7,8-a]imidazole-1,3-quinone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus FTZ F1 alpha 0.0039 0.0085 0.0085
Brugia malayi Cation transporter family protein 0.0018 0.001 0.0031
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0039
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.087 0.3139 0.3139
Echinococcus multilocularis metabotropic glutamate receptor 2 0.008 0.0236 0.0236
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0095 0.0095
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.009 0.5354
Mycobacterium ulcerans hypothetical protein 0.0023 0.0026 0.0166
Echinococcus multilocularis FTZ F1 alpha 0.0039 0.0085 0.0085
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0047 0.108
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0039 0.0085 0.0085
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0017 0.0005 0.0011
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.002 0.0018 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0041 0.0095 0.0289
Brugia malayi von Willebrand Factor 0.0051 0.013 0.0396
Entamoeba histolytica hypothetical protein 0.004 0.0091 0.2391
Brugia malayi nuclear hormone receptor family member odr-7 0.0018 0.001 0.003
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0021 0.0021
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0159 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0099 0.3259
Onchocerca volvulus 0.0018 0.001 0.0027
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0072 0.1878
Echinococcus multilocularis dnaJ subfamily B 0.0439 0.1555 0.1555
Brugia malayi Sulfatase family protein 0.0019 0.0011 0.0034
Loa Loa (eye worm) hypothetical protein 0.005 0.0127 0.0388
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.001 0.001
Trichomonas vaginalis DNA helicase recq, putative 0.0034 0.0068 0.0153
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0051 0.013 0.457
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0216 0.573
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0013 0.0017
Onchocerca volvulus 0.0026 0.0037 0.0099
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0018 0.0041
Echinococcus granulosus lamin 0.009 0.0272 0.0272
Brugia malayi von Willebrand factor type A domain containing protein 0.0051 0.013 0.0396
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.001 0.001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0018 0.001 0.001
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0095 0.0219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0039 0.0085 0.0258
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Schistosoma mansoni ap endonuclease 0.0059 0.0159 0.0367
Schistosoma mansoni survival motor neuron protein 0.0052 0.0135 0.0311
Brugia malayi EGF-like domain containing protein 0.005 0.0127 0.0388
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0095 0.0219
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0013
Brugia malayi nuclear receptor NHR-67 0.0018 0.001 0.003
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0041 0.0095 0.2499
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.009 0.009
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0004 0.0026
Mycobacterium ulcerans aldehyde dehydrogenase 0.0269 0.0932 1
Toxoplasma gondii PAN/Apple domain-containing protein 0.0017 0.0004 0.0026
Leishmania major ATP-dependent phosphofructokinase 0.0118 0.0375 0.3942
Echinococcus multilocularis nuclear receptor nhr 48 0.0018 0.001 0.001
Brugia malayi ecdysone receptor 0.0018 0.001 0.003
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0031 0.0058 0.154
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0159 0.0484
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Schistosoma mansoni slit 0.005 0.0127 0.0294
Schistosoma mansoni thyroid hormone receptor 0.0314 0.1097 0.2534
Loa Loa (eye worm) nuclear receptor NHR-67 0.0018 0.001 0.003
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0018 0.001 0.0031
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.001 0.0031
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0043 0.0102 0.0102
Echinococcus granulosus neurogenic locus notch protein 0.005 0.0127 0.0127
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0216 0.0216
Schistosoma mansoni rotamase 0.0036 0.0075 0.0173
Brugia malayi hypothetical protein 0.002 0.0018 0.0055
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0072 0.0642
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0131 0.0424 0.0979
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0159 0.4207
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0109 0.0109
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0017 0.0004 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0131 0.0424 0.0979
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.0883 0.0883
Entamoeba histolytica hypothetical protein 0.0041 0.0095 0.2499
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0072 0.1878
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0023 0.0026 0.008
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0216 0.2207
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0072 0.1628
Schistosoma mansoni nAChR subunit 0.0018 0.001 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0085 0.0258
Brugia malayi cytoplasmic intermediate filament protein 0.0048 0.0119 0.0364
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0018 0.001 0.0031
Onchocerca volvulus 0.0051 0.013 0.0347
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.009 0.0212
Schistosoma mansoni nuclear hormone receptor 0.0018 0.001 0.0023
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0375 1
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0018 0.001 0.001
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0109 0.0333
Loa Loa (eye worm) glutamate receptor 0.0038 0.0081 0.0247
Echinococcus multilocularis dna polymerase eta 0.0019 0.0013 0.0013
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0216 0.573
Toxoplasma gondii subtilisin SUB12 0.0017 0.0004 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0043 0.0102 0.0102
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.006 0.0112
Toxoplasma gondii aldehyde dehydrogenase 0.0269 0.0932 1
Echinococcus granulosus geminin 0.0182 0.0611 0.0611
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0086 0.026 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0039 0.0085 0.0258
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.001 0.001
Brugia malayi phosphofructokinase 0.0118 0.0375 0.1144
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0018 0.001 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0269 0.0932 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.002 0.0018 0.0055
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.01 0.0309 0.0714
Echinococcus granulosus intermediate filament protein 0.009 0.0272 0.0272
Onchocerca volvulus 0.0051 0.013 0.0347
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.0791
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.006 0.0627
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0095 0.0225
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0118 0.0375 0.0719
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0095 0.0095
Plasmodium falciparum thrombospondin-related anonymous protein 0.0051 0.013 0.457
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0095 0.0225
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.001 0.001
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0039 0.0085 0.0226
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0085 0.0258
Echinococcus granulosus cpg binding protein 0.0033 0.0063 0.0063
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0095 0.0219
Schistosoma mansoni hypothetical protein 0.0182 0.0611 0.1411
Brugia malayi laminin-like protein K08C7.3 precursor 0.005 0.0127 0.0388
Brugia malayi hypothetical protein 0.002 0.0018 0.0055
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0047 0.0485
Echinococcus granulosus thyroid hormone receptor alpha 0.0018 0.001 0.001
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0095 0.0095
Entamoeba histolytica hypothetical protein 0.004 0.0091 0.2391
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.002 0.0018 0.0041
Brugia malayi orphan nuclear receptor NR2E1 0.0018 0.001 0.003
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0048 0.0119 0.0364
Schistosoma mansoni steroid hormone receptor ad4bp 0.0039 0.0085 0.0195
Brugia malayi hypothetical protein 0.004 0.0091 0.0277
Trichomonas vaginalis rotamase, putative 0.0036 0.0075 0.0171
Echinococcus multilocularis neurogenic locus notch protein 0.005 0.0127 0.0127
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0039 0.0085 0.0195
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0039 0.0085 0.0258
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.006 0.0968
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0159 0.0302
Brugia malayi laminin alpha chain 0.005 0.0127 0.0388
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0095 0.0095
Schistosoma mansoni coup transcription factor 0.0039 0.0085 0.0195
Treponema pallidum hypothetical protein 0.0051 0.013 0.0247
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0068 0.0605
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.001 0.0031
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.006 0.1635
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0159 0.1588
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0159 0.4207
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0269 0.0932 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0039 0.0085 0.0258
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0095 0.0095
Echinococcus granulosus dna polymerase eta 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0039
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0109 0.0263
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0039 0.0085 0.0085
Schistosoma mansoni intermediate filament proteins 0.009 0.0272 0.0628
Loa Loa (eye worm) hypothetical protein 0.0041 0.0095 0.0289
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0055
Onchocerca volvulus 0.0052 0.0135 0.0361
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0095 0.0095
Brugia malayi photoreceptor-specific nuclear receptor 0.0039 0.0085 0.0258
Brugia malayi von Willebrand factor type A domain containing protein 0.0051 0.013 0.0396
Onchocerca volvulus 0.0018 0.001 0.0026
Loa Loa (eye worm) hypothetical protein 0.0041 0.0095 0.0289
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0034
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Onchocerca volvulus 0.0039 0.0085 0.0226
Entamoeba histolytica hypothetical protein 0.0041 0.0095 0.2499
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0258
Onchocerca volvulus 0.0018 0.001 0.0027
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.009 0.009
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.001 0.001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0012
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.01 0.0309 0.0714
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.001 0.0031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0085 0.0085
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0018 0.001 0.001
Toxoplasma gondii microneme protein MIC4 0.0017 0.0004 0.0026
Brugia malayi nuclear hormone receptor 0.0018 0.001 0.003
Toxoplasma gondii endonuclease IV APN 0.0086 0.026 0.2772
Schistosoma mansoni nAChR subunit 0.0018 0.001 0.0023
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0085 0.0258
Brugia malayi hypothetical protein 0.0041 0.0095 0.0289
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0039 0.0085 0.0085
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0051 0.013 0.2707
Loa Loa (eye worm) hypothetical protein 0.01 0.0309 0.0943
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0012
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0004 0.0026
Brugia malayi nuclear hormone receptor family member nhr-6 0.0018 0.001 0.003
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0276 0.0956 0.0956
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0018 0.001 0.003
Brugia malayi nuclear hormone receptor 0.0039 0.0085 0.0258
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0159 0.3422
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0064
Schistosoma mansoni lipoxygenase 0.0059 0.0161 0.0371
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0299
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0039 0.0085 0.0085
Mycobacterium ulcerans endonuclease IV 0.0086 0.026 0.2697
Entamoeba histolytica hypothetical protein 0.0051 0.013 0.3437
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0086 0.026 0.5923
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0023 0.0026 0.0166
Echinococcus granulosus leukotriene A 4 hydrolase 0.0249 0.0857 0.0857
Brugia malayi hypothetical protein 0.0051 0.013 0.0396
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0159 0.1603
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0013 0.0013
Brugia malayi von Willebrand factor type A domain containing protein 0.0051 0.013 0.0396
Schistosoma mansoni rab6-interacting 0.0021 0.0021 0.0048
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0013 0.0029
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0039 0.0085 0.0258
Brugia malayi Metabotropic glutamate receptor precursor. 0.0095 0.0293 0.0894
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0047 0.1208
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0086 0.026 0.6684
Echinococcus multilocularis pikachurin 0.005 0.0127 0.0127
Loa Loa (eye worm) ACC-1 protein 0.0018 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0034
Schistosoma mansoni hypothetical protein 0.0051 0.013 0.03
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Brugia malayi Cytochrome P450 family protein 0.0075 0.022 0.067
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.001 0.0023
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0031 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.005 0.0127 0.0294
Brugia malayi CXXC zinc finger family protein 0.0031 0.0056 0.0172
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.009 0.2372
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0013 0.0299
Leishmania major hypothetical protein, conserved 0.0028 0.0047 0.0369
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0012
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0095 0.0095
Onchocerca volvulus 0.009 0.0272 0.0727
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0018 0.001 0.001
Echinococcus granulosus collagen alpha 1VII chain 0.0051 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0095 0.0289
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0075 0.0228
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0018 0.001 0.001
Loa Loa (eye worm) RecQ helicase 0.0045 0.0109 0.0333
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.0883 0.0883
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0095 0.0095
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0021 0.0021
Brugia malayi 6-phosphofructokinase 0.0118 0.0375 0.1144
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0018 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0095 0.0225
Loa Loa (eye worm) cytochrome P450 family protein 0.0075 0.022 0.067
Schistosoma mansoni loxhd1 0.0021 0.0021 0.0048
Toxoplasma gondii microneme protein MIC17C 0.0017 0.0004 0.0026
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0146 0.0338
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0037 0.0955
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.001 0.001
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0018 0.001 0.0031
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0019 0.0011 0.003
Loa Loa (eye worm) steroid hormone receptor 0.0039 0.0085 0.0258
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Schistosoma mansoni DNA helicase recq5 0.0031 0.0058 0.0133
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.006 0.1562
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0131
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Echinococcus granulosus pikachurin 0.005 0.0127 0.0127
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0216 0.0498
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0375 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.006 0.0131
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.006 0.0968
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.009 0.2372
Echinococcus granulosus dnaJ subfamily B 0.0439 0.1555 0.1555
Schistosoma mansoni ap endonuclease 0.0059 0.0159 0.0367
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0051 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0258
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0299
Echinococcus multilocularis slit 2 protein 0.005 0.0127 0.0127
Brugia malayi hypothetical protein 0.0041 0.0095 0.0289
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0051 0.013 0.0396
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.013 0.0396
Schistosoma mansoni nAChR subunit 0.0018 0.001 0.0023
Echinococcus granulosus metabotropic glutamate receptor 5 0.0117 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Onchocerca volvulus 0.0017 0.0004 0.0011
Schistosoma mansoni nuclear receptor 0.0018 0.001 0.0023
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0004 0.0026
Plasmodium vivax thrombospondin-related anonymous protein 0.0051 0.013 0.2707
Echinococcus granulosus expressed protein 0.0036 0.0075 0.0075
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0031 0.0058 0.0058
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.01 0.0309 0.0309
Loa Loa (eye worm) hypothetical protein 0.0055 0.0146 0.0446
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0021 0.0064
Schistosoma mansoni RAR-like nuclear receptor 0.0039 0.0085 0.0195
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0018 0.001 0.0023
Brugia malayi nuclear receptor RXR 0.0018 0.001 0.003
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0039 0.0085 0.0195
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0299
Echinococcus granulosus nAChR subunit 0.0018 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0095 0.0225
Entamoeba histolytica hypothetical protein, conserved 0.0051 0.013 0.3437
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0051 0.013 0.2707
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0039 0.0085 0.0085
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0047 0.064
Schistosoma mansoni hypothetical protein 0.0439 0.1555 0.3591
Entamoeba histolytica recQ family helicase, putative 0.0034 0.0068 0.1788
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0039 0.0085 0.0195
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.009 0.009
Toxoplasma gondii microneme protein, putative 0.0017 0.0004 0.0026
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0095 0.0095
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0058 0.0176
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0118 0.0375 1
Plasmodium vivax hypothetical protein, conserved 0.0051 0.013 0.2707
Treponema pallidum 76K protein 0.0051 0.013 0.0247
Loa Loa (eye worm) DR-78 0.0018 0.001 0.003
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.001 0.0031
Schistosoma mansoni nuclear receptor nhr-48 0.0018 0.001 0.0023
Trichomonas vaginalis set domain proteins, putative 0.1034 0.374 1
Schistosoma mansoni hypothetical protein 0.004 0.0091 0.021
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0018 0.001 0.001
Schistosoma mansoni lipoxygenase 0.0021 0.0021 0.0048
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0095 0.0289
Schistosoma mansoni hypothetical protein 0.0021 0.0021 0.0048
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0117 0.0374 0.1141
Brugia malayi von Willebrand factor type A domain containing protein 0.0051 0.013 0.0396
Onchocerca volvulus 0.0017 0.0004 0.0011
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0085 0.0195
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0023 0.0026 0.0071
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0095 0.0095
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0159 0.0396
Brugia malayi nuclear receptor NHR-88 0.0018 0.001 0.003
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0018 0.001 0.001
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.001 0.001
Onchocerca volvulus 0.009 0.0272 0.0727
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0018 0.001 0.001
Brugia malayi Cation transporter family protein 0.0018 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.004 0.009 0.0212
Entamoeba histolytica hypothetical protein, conserved 0.0051 0.013 0.3437
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0131 0.0424 0.0424
Brugia malayi hypothetical protein 0.0018 0.001 0.003
Schistosoma mansoni hypothetical protein 0.0182 0.0611 0.1411
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0058 0.0603
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0095 0.0289
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0216 0.0658
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.01 0.0309 0.0943
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Echinococcus granulosus metabotropic glutamate receptor 2 0.008 0.0236 0.0236
Schistosoma mansoni nuclear hormone receptor 0.0018 0.001 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0085 0.0258
Loa Loa (eye worm) TK/ROR protein kinase 0.0026 0.0037 0.0113
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0059 0.0161 0.0161
Brugia malayi Cation transporter family protein 0.0018 0.001 0.0031
Echinococcus granulosus histone lysine methyltransferase setb 0.0131 0.0424 0.0424
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.001 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0018 0.0055
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0031 0.0058 0.0058
Brugia malayi tailless protein 0.0018 0.001 0.003
Brugia malayi hypothetical protein 0.0114 0.0363 0.1108
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0085 0.0258
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Schistosoma mansoni rab6-interacting 0.0021 0.0021 0.0048
Schistosoma mansoni blooms syndrome DNA helicase 0.0029 0.0051 0.0118
Onchocerca volvulus 0.0017 0.0004 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0131
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0131
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0021 0.0021
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.009 0.009
Loa Loa (eye worm) CUTiclin family member 0.0051 0.013 0.0396
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0095 0.0219
Onchocerca volvulus 0.0017 0.0004 0.0011
Brugia malayi Steroid receptor seven-up type 2 0.0039 0.0085 0.0258
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0013 0.0039
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0118 0.0375 0.3953
Echinococcus granulosus bloom syndrome protein 0.0045 0.0109 0.0109
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0249 0.0857 0.198
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0095 0.0219
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0269 0.0932 1
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0051 0.013 0.0396
Brugia malayi PXA domain containing protein 0.0041 0.0095 0.0289
Loa Loa (eye worm) hypothetical protein 0.0042 0.0096 0.0292
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Onchocerca volvulus 0.0018 0.001 0.0027
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0269 0.0932 0.0932
Brugia malayi von Willebrand factor type A domain containing protein 0.0051 0.013 0.0396
Echinococcus multilocularis voltage dependent calcium channel subunit 0.1246 0.4517 0.4517
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0131 0.0424 0.4537
Giardia lamblia Sgs1 DNA helicase, putative 0.0031 0.0058 0.3151
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0175 0.1866
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0018 0.001 0.0031
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0047 0.108
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0013 0.0017
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0018 0.001 0.001
Onchocerca volvulus 0.0131 0.0424 0.1133
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Echinococcus multilocularis expressed protein 0.0805 0.2898 0.2898
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0095 0.0095
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0039 0.0085 0.0085
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0131
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0258
Brugia malayi von Willebrand factor type A domain containing protein 0.0051 0.013 0.0396
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0108 0.0341 0.0788
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0018 0.001 0.0031
Toxoplasma gondii microneme protein MIC17A 0.0017 0.0004 0.0026
Echinococcus multilocularis cpg binding protein 0.0033 0.0063 0.0063
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0095 0.0095
Schistosoma mansoni cpg binding protein 0.0033 0.0063 0.0145
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0068 0.1535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0039 0.0085 0.0258
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0086 0.026 0.0794
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Echinococcus granulosus voltage dependent calcium channel subunit 0.1246 0.4517 0.4517
Echinococcus multilocularis expressed protein 0.0036 0.0075 0.0075
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.006 0.1635
Onchocerca volvulus 0.1034 0.374 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0055
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0018 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0039 0.0085 0.0258
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0018 0.001 0.0023
Schistosoma mansoni aldehyde dehydrogenase 0.0269 0.0932 0.2153
Onchocerca volvulus Protein ultraspiracle homolog 0.0039 0.0085 0.0226
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0058 0.0603
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0039 0.0085 0.0085
Giardia lamblia DINP protein human, muc B family 0.0019 0.0013 0.0107
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.001 0.0031
Onchocerca volvulus Putative nachr subunit 0.0018 0.001 0.0027
Plasmodium vivax SET domain protein, putative 0.0131 0.0424 1
Echinococcus multilocularis lamin 0.009 0.0272 0.0272
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0095 0.0289
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.009 0.0208
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.01 0.0309 0.0309
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0095 0.0095
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0039 0.0085 0.0085
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0131 0.0424 0.0979
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.009 0.0208
Onchocerca volvulus 0.0031 0.0056 0.0151
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0018 0.001 0.001
Schistosoma mansoni DNA polymerase eta 0.0019 0.0013 0.0029
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0159 0.0396
Echinococcus multilocularis thyroid hormone receptor alpha 0.0314 0.1097 0.1097
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0075 0.0228
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0125 0.0404 0.0404
Echinococcus multilocularis lamin dm0 0.009 0.0272 0.0272
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0095 0.0095
Echinococcus granulosus tumor protein p63 0.0378 0.133 0.133
Entamoeba histolytica hypothetical protein 0.004 0.0091 0.2391
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.009 0.0275
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0013 0.0004
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0013 0.0029
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.004 0.0417
Brugia malayi nuclear receptor NHR-88 0.0039 0.0085 0.0258
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0095 0.0289
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0004 0.0012
Schistosoma mansoni nuclear receptor 0.0018 0.001 0.0023
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0018 0.001 0.0031
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0602 0.2155 0.4976
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0031 0.0058 0.0176
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0142
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0026 0.0166
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.001 0.0026
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0095 0.0219
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0095 0.0289
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0375 1
Schistosoma mansoni nAChR subunit 0.0018 0.001 0.0023
Schistosoma mansoni hypothetical protein 0.0276 0.0956 0.2208
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0159 0.0484
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.001 0.001
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.001 0.001
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0033 0.01
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0258
Brugia malayi hypothetical protein 0.0028 0.0047 0.0142
Loa Loa (eye worm) LGC-31 protein 0.0018 0.001 0.0031
Onchocerca volvulus 0.0017 0.0004 0.0011
Echinococcus multilocularis geminin 0.0182 0.0611 0.0611
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.004 0.009 0.0275
Loa Loa (eye worm) hypothetical protein 0.005 0.0127 0.0388
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.002 0.0018 0.0018
Schistosoma mansoni aldehyde dehydrogenase 0.0269 0.0932 0.2153
Brugia malayi hypothetical protein 0.0018 0.001 0.003
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0131
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0018 0.0055
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0258
Onchocerca volvulus 0.0018 0.001 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0013
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Loa Loa (eye worm) nuclear hormone receptor 0.0018 0.001 0.003
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0051 0.013 0.2707
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0031 0.0058 0.0058
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0095 0.0095
Brugia malayi von Willebrand factor type A domain containing protein 0.0051 0.013 0.0396
Toxoplasma gondii exonuclease III APE 0.0059 0.0159 0.1689
Echinococcus multilocularis ecdysone induced protein 78C 0.0039 0.0085 0.0085
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0068 0.1788
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0039 0.0085 0.0258
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.0375 1
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0095 0.0219
Echinococcus granulosus expressed protein 0.0805 0.2898 0.2898
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0101 0.0101
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.009 0.009
Onchocerca volvulus 0.0017 0.0004 0.0011
Brugia malayi 6-phosphofructokinase 0.0118 0.0375 0.1144
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0375 0.0976
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0095 0.0095
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0375 0.0976
Echinococcus multilocularis tumor protein p63 0.0378 0.133 0.133
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0256 0.0883 0.2693
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0375 0.0976
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.009 0.0272 0.0829
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0091 0.021
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0051 0.013 0.0319
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0095 0.0289
Brugia malayi intermediate filament protein 0.009 0.0272 0.0829
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Schistosoma mansoni cell polarity protein 0.005 0.0127 0.0294
Loa Loa (eye worm) hypothetical protein 0.0041 0.0095 0.0289
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.001 0.0023
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.0375 0.0866
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0201 0.0464
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0085 0.0085
Onchocerca volvulus 0.0055 0.0146 0.0391
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0051 0.013 0.138
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Brugia malayi hypothetical protein 0.0021 0.0021 0.0064
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0159 0.4029
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0095 0.0219
Entamoeba histolytica elongation factor-2 kinase, putative 0.0051 0.013 0.3437
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Brugia malayi von Willebrand factor type A domain containing protein 0.0051 0.013 0.0396
Echinococcus multilocularis nAChR subunit 0.0018 0.001 0.001
Mycobacterium ulcerans epimerase 0.0023 0.0026 0.0166
Brugia malayi PXA domain containing protein 0.0041 0.0095 0.0289
Loa Loa (eye worm) intermediate filament protein 0.009 0.0272 0.0829
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.001 0.0031
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0004 0.0012
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0086 0.026 0.2697
Onchocerca volvulus 0.0018 0.001 0.0027
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0018 0.001 0.0031
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.001 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0095 0.0219
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.0375 0.0866
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0059 0.0161 0.0161
Brugia malayi Nuclear hormone receptor E75 0.0018 0.001 0.003
Loa Loa (eye worm) ACC-1 protein 0.0018 0.001 0.0031
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0013 0.0017
Loa Loa (eye worm) glutamate receptor 0.0095 0.0293 0.0894
Brugia malayi metabotropic glutamate receptor type 2 0.0046 0.0114 0.0347
Onchocerca volvulus 0.0018 0.001 0.0027
Onchocerca volvulus 0.0051 0.013 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0085 0.0258
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0018 0.001 0.0031
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0018 0.001 0.0023
Brugia malayi ecdysteroid receptor 0.0039 0.0085 0.0258
Echinococcus granulosus dna polymerase kappa 0.0019 0.0013 0.0013
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0039 0.0085 0.0258
Schistosoma mansoni retinoic acid receptor RXR 0.0039 0.0085 0.0195
Mycobacterium ulcerans 6-phosphofructokinase 0.0118 0.0375 0.3953
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.1195 0.433 1
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.005 0.0127 0.0388
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0131
Echinococcus granulosus tissue type plasminogen activator 0.0026 0.0037 0.0037
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0018 0.001 0.0031
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.001 0.001
Brugia malayi conserved hypotetical protein 0.0018 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0037 0.0113
Onchocerca volvulus 0.0021 0.0021 0.0056
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0047 0.0937
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0004 0.0026
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0216 0.573
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0018 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0684 0.2454 0.7484
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0075 0.0171
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.01
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0159 0.1603
Brugia malayi nuclear receptor RXR 0.002 0.0018 0.0055
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0131 0.0424 0.0424
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0216 0.5598
Loa Loa (eye worm) hypothetical protein 0.0131 0.0424 0.1292
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0159 0.5776
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0095 0.0095
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0027 0.0043 0.0538
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.009 0.2372
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0039 0.0085 0.0258
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.001 0.001
Leishmania major hypothetical protein, conserved 0.0026 0.0037 0.0267
Schistosoma mansoni hypothetical protein 0.0026 0.0037 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0039 0.0085 0.0258
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0159 0.4207
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) phosphofructokinase 0.0118 0.0375 0.1144
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.006 0.3304
Toxoplasma gondii microneme protein MIC2 0.0051 0.013 0.138
Schistosoma mansoni nAChR subunit 0.0018 0.001 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0085 0.0258
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.001 0.0031
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0039 0.0085 0.0195
Onchocerca volvulus 0.0021 0.0021 0.0056
Echinococcus multilocularis voltage dependent calcium channel subunit 0.2739 1 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0064
Onchocerca volvulus 0.0018 0.001 0.0026
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0249 0.0857 0.2614
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.009 0.0842
Brugia malayi hypothetical protein 0.0019 0.0011 0.0034
Schistosoma mansoni cpg binding protein 0.0031 0.0056 0.013
Schistosoma mansoni thyroid hormone receptor 0.0314 0.1097 0.2534
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.009 0.0272 0.0829
Loa Loa (eye worm) hypothetical protein 0.0041 0.0095 0.0289
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.005 0.0127 0.0388
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0095 0.0289
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0039 0.0085 0.0258
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0216 0.0658
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0258
Onchocerca volvulus 0.0051 0.013 0.0347
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0018 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0055
Onchocerca volvulus 0.0051 0.013 0.0347
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0072 0.0754
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.001 0.0023
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0086 0.026 0.0791
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0058 0.0176
Schistosoma mansoni hypothetical protein 0.0051 0.013 0.03
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0101 0.0101
Brugia malayi excitatory GABA receptor EXP-1A 0.0018 0.001 0.0031
Loa Loa (eye worm) CUTiclin-Like family member 0.0051 0.013 0.0396
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0109 0.0263
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Echinococcus granulosus RUN 0.0021 0.0021 0.0021
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0909 0.3279 1
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Onchocerca volvulus 0.0017 0.0004 0.0011
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0047 0.1208
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0276 0.0956 0.0956
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0018 0.001 0.001
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.001 0.001
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0095 0.0219
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0012
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.009 0.2137
Schistosoma mansoni cpg binding protein 0.0033 0.0063 0.0145
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0059 0.0159 0.5
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0051 0.013 0.0396
Echinococcus multilocularis musashi 0.009 0.0272 0.0272
Plasmodium falciparum cysteine repeat modular protein 1 0.0026 0.0037 0.0684
Schistosoma mansoni hypothetical protein 0.0052 0.0135 0.0311
Toxoplasma gondii microneme protein MIC17B 0.0017 0.0004 0.0026
Echinococcus granulosus 6 phosphofructokinase 0.0118 0.0375 0.0375
Brugia malayi hypothetical protein 0.0256 0.0883 0.2693
Brugia malayi Pre-SET motif family protein 0.0131 0.0424 0.1292
Onchocerca volvulus 0.0017 0.0004 0.0011
Loa Loa (eye worm) abnormal epIthelia family member 0.005 0.0127 0.0388
Brugia malayi PAN domain containing protein 0.0017 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Brugia malayi Nuclear hormone receptor E75 0.0018 0.001 0.003
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0095 0.0219
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0159 0.0159
Schistosoma mansoni nAChR subunit 0.0018 0.001 0.0023
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0117 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0552 0.1968 0.6002
Brugia malayi Pre-SET motif family protein 0.0909 0.3279 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.0375 0.1144
Trichomonas vaginalis rotamase, putative 0.0035 0.0072 0.0162
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0159 0.0159
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.0375 0.1144
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0299
Brugia malayi hypothetical protein 0.0262 0.0907 0.2765
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0095 0.0225
Onchocerca volvulus 0.0051 0.013 0.0347
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0051 0.013 0.457
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0056 0.0172
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0095 0.0289
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Toxoplasma gondii hypothetical protein 0.0017 0.0004 0.0026
Loa Loa (eye worm) hypothetical protein 0.0088 0.0266 0.081
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0018 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0055
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0095 0.0219
Schistosoma mansoni lamin 0.009 0.0272 0.0628
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0269 0.0932 1
Schistosoma mansoni metabotropic glutamate receptor 0.008 0.0236 0.0546
Echinococcus granulosus ecdysone induced protein 78C 0.0039 0.0085 0.0085
Schistosoma mansoni laminin gamma-3 chain 0.005 0.0127 0.0294
Loa Loa (eye worm) hypothetical protein 0.0042 0.0096 0.0292
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.001 0.001
Echinococcus multilocularis 6 phosphofructokinase 0.0118 0.0375 0.0375
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0039 0.0085 0.0195
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.006 0.0627
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.009 0.0212
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.001 0.001
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0249 0.0857 0.0857
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.1432 0.5202 1
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0004 0.0026
Onchocerca volvulus 0.0017 0.0004 0.0011
Brugia malayi steroid hormone receptor 0.0039 0.0085 0.0258
Schistosoma mansoni nAChR subunit 0.0018 0.001 0.0023
Schistosoma mansoni zinc finger protein 0.0018 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0258
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0095 0.0219
Brugia malayi Protein kinase domain containing protein 0.0026 0.0037 0.0113
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0018 0.001 0.0031
Brugia malayi Zona pellucida-like domain containing protein 0.0051 0.013 0.0396
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0135 0.0411
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.009 0.009
Schistosoma mansoni serine-rich repeat protein 0.0643 0.2306 0.5324
Onchocerca volvulus 0.0051 0.013 0.0347
Onchocerca volvulus 0.0017 0.0004 0.0011
Schistosoma mansoni lamin 0.009 0.0272 0.0628
Brugia malayi Cache domain containing protein 0.0552 0.1968 0.6002
Schistosoma mansoni metabotropic glutamate receptor 0.0046 0.0114 0.0263
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.006 0.0627
Schistosoma mansoni hypothetical protein 0.0643 0.2306 0.5324
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0072 0.1878
Toxoplasma gondii kringle domain-containing protein 0.0026 0.0037 0.0383
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Brugia malayi follicle stimulating hormone receptor 0.0256 0.0883 0.2691
Echinococcus granulosus slit 2 protein 0.005 0.0127 0.0127
Brugia malayi Intermediate filament tail domain containing protein 0.009 0.0272 0.0829
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0021 0.0021
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.01 0.0309 0.0714
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0095 0.0289
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0095 0.0095
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0095 0.0289
Entamoeba histolytica hypothetical protein 0.004 0.0091 0.2391
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0026 0.0037 0.0405
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.003
Brugia malayi hypothetical protein 0.0021 0.0021 0.0064
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0033 0.01
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.001 0.001
Brugia malayi Doublecortin family protein 0.0021 0.0021 0.0064
Schistosoma mansoni polycystin 1-related 0.0021 0.0021 0.0048
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0013 0.0004
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0396
Echinococcus multilocularis tissue type plasminogen activator 0.0026 0.0037 0.0037
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0033 0.01
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0004 0.0026
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0095 0.0219
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0039 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0055
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0085 0.0195
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0091 0.0091
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0018 0.001 0.0031
Echinococcus granulosus nuclear receptor nhr 48 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0095 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0095 0.0225
Loa Loa (eye worm) hypothetical protein 0.0043 0.0102 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0039 0.0085 0.0258
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0031
Onchocerca volvulus 0.0017 0.0004 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0375 0.0976
Echinococcus granulosus lamin dm0 0.009 0.0272 0.0272
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.0375 1
Chlamydia trachomatis endonuclease IV 0.0086 0.026 1
Brugia malayi Zona pellucida-like domain containing protein 0.0051 0.013 0.0396
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.001 0.001
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0031 0.0058 0.0176
Schistosoma mansoni DNA helicase recq1 0.0031 0.0058 0.0133
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0269 0.0932 0.0932
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0039 0.0085 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0095 0.0225
Echinococcus multilocularis RUN 0.0021 0.0021 0.0021
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0256 0.0883 0.2691
Onchocerca volvulus Bile acid receptor homolog 0.0039 0.0085 0.0226
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.001 0.0026
Brugia malayi hypothetical protein 0.0018 0.001 0.003
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0091 0.0091
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0004 0.0012
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0013 0.0017
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0013 0.0299
Brugia malayi Kringle domain containing protein 0.0026 0.0037 0.0113
Toxoplasma gondii hypothetical protein 0.0017 0.0004 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0131 0.0424 0.0979
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0258

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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