Detailed information for compound 902342

Basic information

Technical information
  • TDR Targets ID: 902342
  • Name: 2-phenyl-5-(4-propoxyphenyl)-5,10b-dihydro-1H -pyrazolo[1,5-c][1,3]benzoxazine
  • MW: 384.47 | Formula: C25H24N2O2
  • H donors: 0 H acceptors: 0 LogP: 5.7 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCOc1ccc(cc1)C1Oc2ccccc2C2N1N=C(C2)c1ccccc1
  • InChi: 1S/C25H24N2O2/c1-2-16-28-20-14-12-19(13-15-20)25-27-23(21-10-6-7-11-24(21)29-25)17-22(26-27)18-8-4-3-5-9-18/h3-15,23,25H,2,16-17H2,1H3
  • InChiKey: HGMSWLATFIDTLF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Oprea1_774207
  • EU-0005273
  • STOCK2S-10912

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Cathepsin L homolog 0.0223 0.0791 0.5939
Loa Loa (eye worm) hypothetical protein 0.0064 0.0172 0.0256
Brugia malayi cathepsin B-like cysteine proteinase 0.1028 0.3919 0.5821
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0106 0.0157
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Loa Loa (eye worm) hypothetical protein 0.0061 0.0162 0.024
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Toxoplasma gondii isocitrate dehydrogenase 0.0025 0.0022 0.0157
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0047 0.0106 0.0157
Leishmania major cathepsin L-like protease 0.0223 0.0791 0.5921
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0065 0.0178 0.1337
Echinococcus multilocularis neuropeptide s receptor 0.075 0.2839 0.4216
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0021 0.0025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0065 0.0178 0.0264
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0113 0.0363 0.0538
Echinococcus granulosus histone lysine methyltransferase setb 0.0028 0.0035 0.005
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0021 0.0252
Loa Loa (eye worm) hypothetical protein 0.0183 0.0634 0.0941
Mycobacterium ulcerans oxidoreductase 0.0183 0.0634 0.0614
Plasmodium vivax ataxin-2 like protein, putative 0.0061 0.0162 0.2038
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.2593 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0178 0.1337
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0116 0.0376 0.0383
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.2411 0.929 1
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Schistosoma mansoni transcription factor LCR-F1 0.0063 0.0168 0.0248
Brugia malayi SWIRM domain containing protein 0.0183 0.0634 0.094
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0047 0.0106 0.0157
Giardia lamblia Cathepsin L precursor 0.0065 0.0178 0.133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0099 0.031 0.046
Brugia malayi nuclear receptor RXR 0.0047 0.0106 0.0157
Onchocerca volvulus 0.002 0.0002 0.0004
Loa Loa (eye worm) DR-78 0.0047 0.0106 0.0158
Schistosoma mansoni steroid hormone receptor ad4bp 0.0099 0.031 0.046
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0178 0.1337
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0183 0.0634 0.8015
Echinococcus multilocularis musashi 0.002 0.0002 0.0001
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0223 0.0791 1
Loa Loa (eye worm) acetyltransferase 0.0113 0.0363 0.0539
Brugia malayi Bromodomain containing protein 0.0023 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0083
Leishmania major cathepsin L-like protease 0.0223 0.0791 0.5921
Brugia malayi Common central domain of tyrosinase family protein 0.0173 0.0595 0.0882
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Onchocerca volvulus Cathepsin L homolog 0.0223 0.0791 0.5939
Toxoplasma gondii histone lysine-specific demethylase 0.0183 0.0634 0.4743
Brugia malayi hypothetical protein 0.0047 0.0106 0.0157
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0183 0.0634 0.094
Echinococcus granulosus cathepsin l1 0.0159 0.0542 0.0804
Brugia malayi cathepsin F-like cysteine proteinase 0.0064 0.0172 0.0255
Schistosoma mansoni tyrosinase precursor 0.0173 0.0595 0.0882
Brugia malayi nuclear hormone receptor 0.0099 0.031 0.046
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0086 0.064
Brugia malayi orphan nuclear receptor NR2E1 0.0047 0.0106 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0099 0.031 0.046
Plasmodium vivax hypothetical protein, conserved 0.0183 0.0634 0.8015
Entamoeba histolytica cysteine proteinase, putative 0.0223 0.0791 0.9312
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0041 0.0086 0.0515
Brugia malayi Cathepsin L-like precursor 0.0223 0.0791 0.1173
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0065 0.0178 0.2248
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1028 0.3919 0.5821
Echinococcus granulosus microtubule associated protein 2 0.0656 0.2472 0.3672
Brugia malayi RNA, U transporter 1 0.0068 0.019 0.028
Schistosoma mansoni hypothetical protein 0.0256 0.0921 0.1367
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0065 0.0178 0.0264
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0025 0.0022 0.0056
Trypanosoma cruzi PAB1-binding protein , putative 0.0061 0.0162 0.0413
Onchocerca volvulus Cathepsin L homolog 0.0065 0.0178 0.1335
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0038 0.0282
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0099 0.031 0.046
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0027 0.0031 0.0044
Brugia malayi Papain family cysteine protease containing protein 0.0223 0.0791 0.1173
Giardia lamblia Cathepsin L precursor 0.0065 0.0178 0.133
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0065 0.0178 0.1337
Onchocerca volvulus 0.0031 0.0045 0.0333
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.01 0.0315 0.0466
Toxoplasma gondii cathepsin CPC1 0.0065 0.0178 0.133
Brugia malayi Cathepsin L-like precursor 0.0159 0.0542 0.0804
Echinococcus granulosus lysine specific histone demethylase 1A 0.0183 0.0634 0.094
Schistosoma mansoni cathepsin F (C01 family) 0.0159 0.0542 0.0804
Echinococcus multilocularis GPCR, family 2 0.01 0.0315 0.0466
Plasmodium falciparum cysteine proteinase falcipain 1 0.0129 0.0427 0.539
Plasmodium falciparum serine repeat antigen 2 0.0065 0.0178 0.2248
Echinococcus multilocularis tumor protein p63 0.0321 0.1172 0.174
Echinococcus multilocularis importin subunit beta 1 0.0024 0.0018 0.0025
Echinococcus granulosus insulin growth factor 1 receptor beta 0.056 0.2101 0.312
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0173 0.0595 0.0882
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0223 0.0791 0.5921
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0028 0.0035 0.0251
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0041 0.0086 0.0218
Echinococcus multilocularis muscleblind protein 1 0.0355 0.1304 0.1936
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Echinococcus granulosus histone acetyltransferase KAT2B 0.0033 0.0053 0.0078
Schistosoma mansoni tyrosine kinase 0.056 0.2101 0.312
Leishmania major cathepsin L-like protease 0.0286 0.1036 0.7762
Echinococcus granulosus thyroid hormone receptor alpha 0.0047 0.0106 0.0157
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0318 0.1158 0.1719
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0128 0.0189
Brugia malayi nuclear receptor NHR-88 0.0099 0.031 0.046
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0183 0.0634 1
Echinococcus multilocularis mitogen activated protein kinase 0.0041 0.0086 0.0125
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0065 0.0178 0.1337
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0041 0.0086 0.064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0099 0.031 0.0461
Loa Loa (eye worm) cathepsin B 0.0363 0.1335 0.1983
Schistosoma mansoni tyrosinase precursor 0.0173 0.0595 0.0882
Loa Loa (eye worm) hypothetical protein 0.0099 0.031 0.0461
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0183 0.0634 0.4743
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0175 0.0259
Loa Loa (eye worm) hypothetical protein 0.0355 0.1304 0.1937
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0028 0.0035 0.005
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0054 0.0133 0.0997
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0054 0.0133 0.0196
Brugia malayi Furin-like cysteine rich region family protein 0.1752 0.6732 1
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Brugia malayi Latrophilin receptor protein 2 0.01 0.0315 0.0466
Loa Loa (eye worm) RNA binding protein 0.0311 0.1131 0.168
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0099 0.031 0.046
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0133 0.034
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Schistosoma mansoni cellular tumor antigen P53 0.0047 0.0107 0.0157
Onchocerca volvulus 0.0223 0.0791 0.5939
Schistosoma mansoni nuclear receptor 0.0047 0.0106 0.0157
Echinococcus granulosus neuropeptide receptor A26 0.075 0.2839 0.4216
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0099 0.031 0.046
Brugia malayi Papain family cysteine protease containing protein 0.0065 0.0178 0.0264
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0128 0.0189
Plasmodium vivax vivapain-3 0.0129 0.0427 0.539
Brugia malayi jmjC domain containing protein 0.0065 0.0176 0.0259
Schistosoma mansoni lipoxygenase 0.008 0.0235 0.0347
Loa Loa (eye worm) hypothetical protein 0.0223 0.0791 0.1174
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0035 0.005
Echinococcus granulosus lysine specific histone demethylase 1A 0.0183 0.0634 0.094
Echinococcus multilocularis epidermal growth factor receptor 0.1752 0.6732 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0133 0.0877
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0238 0.0849 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0025 0.0022 0.0056
Echinococcus granulosus cathepsin L 0.0129 0.0427 0.0632
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0106 0.0157
Brugia malayi Immunoglobulin I-set domain containing protein 0.0119 0.0389 0.0576
Echinococcus multilocularis cysteine protease 0.0223 0.0791 0.1173
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0099 0.031 0.046
Loa Loa (eye worm) hypothetical protein 0.0355 0.1304 0.1937
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.0106 0.0157
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0027 0.0031 0.0044
Schistosoma mansoni alpha-glucosidase 0.0113 0.0364 0.0539
Loa Loa (eye worm) hypothetical protein 0.0053 0.0128 0.019
Trypanosoma cruzi UDP-galactopyranose mutase 0.0183 0.0634 0.1618
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0223 0.0791 0.5921
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0041 0.0086 0.0218
Schistosoma mansoni amine oxidase 0.0183 0.0634 0.094
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0127 0.0419 0.0621
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0047 0.0106 0.0157
Onchocerca volvulus 0.0032 0.005 0.0367
Brugia malayi hypothetical protein 0.0063 0.0168 0.0248
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1431 0.5484 0.8146
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0099 0.031 0.046
Echinococcus granulosus lipoxygenase domain containing protein 0.0031 0.0045 0.0066
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0065 0.0178 0.133
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0054 0.0133 0.0196
Onchocerca volvulus 0.0223 0.0791 0.5939
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0129 0.0427 0.0632
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0065 0.0178 0.2248
Onchocerca volvulus 0.0223 0.0791 0.5939
Brugia malayi Papain family cysteine protease containing protein 0.0065 0.0178 0.0264
Brugia malayi ecdysone receptor 0.0047 0.0106 0.0157
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0041 0.0086 0.0218
Loa Loa (eye worm) hypothetical protein 0.0065 0.0178 0.0265
Treponema pallidum fructose-bisphosphate aldolase 0.0238 0.0849 1
Echinococcus granulosus cathepsin L cysteine protease 0.0129 0.0427 0.0632
Loa Loa (eye worm) hypothetical protein 0.0173 0.0595 0.0883
Mycobacterium ulcerans monoamine oxidase 0.0183 0.0634 0.0614
Onchocerca volvulus Tyrosine kinase homolog 0.0112 0.036 0.2704
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0065 0.0178 0.133
Entamoeba histolytica hypothetical protein 0.0025 0.0021 0.0247
Loa Loa (eye worm) doublecortin family protein 0.0031 0.0045 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0065 0.0178 0.1337
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0032 0.005 0.0367
Echinococcus multilocularis geminin 0.0648 0.2441 0.3625
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0065 0.0178 0.1337
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0159 0.0542 0.4062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0025 0.0022 0.0033
Echinococcus granulosus epidermal growth factor receptor 0.0942 0.3583 0.5322
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0175 0.1305
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0065 0.0178 0.2248
Echinococcus multilocularis lysosomal alpha glucosidase 0.0131 0.0435 0.0644
Brugia malayi Cathepsin L-like precursor 0.0223 0.0791 0.1173
Loa Loa (eye worm) ShTK domain-containing protein 0.0173 0.0595 0.0883
Echinococcus granulosus lipoxygenase domain containing protein 0.0031 0.0045 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.0849 0.6358
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0136 0.0452 0.0671
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0099 0.031 0.046
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0268 0.0396
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0183 0.0634 0.094
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0065 0.0178 0.0265
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0183 0.0634 0.0941
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.0849 0.6358
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0099 0.031 0.0461
Echinococcus granulosus lysine specific demethylase 5A 0.0024 0.0017 0.0024
Echinococcus multilocularis cysteine protease 0.0223 0.0791 0.1173
Onchocerca volvulus 0.0225 0.0799 0.6001
Brugia malayi hypothetical protein 0.0047 0.0106 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Brugia malayi cathepsin L-like precursor 0.0159 0.0542 0.0804
Plasmodium vivax vivapain-1 0.0129 0.0427 0.539
Schistosoma mansoni cathepsin S (C01 family) 0.0065 0.0178 0.0264
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0065 0.0178 0.2248
Echinococcus multilocularis insulin receptor 0.056 0.2101 0.312
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0175 0.0259
Giardia lamblia Histone acetyltransferase GCN5 0.003 0.0043 0.0311
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0065 0.0178 0.0264
Entamoeba histolytica acetyltransferase, GNAT family 0.003 0.0043 0.0501
Echinococcus granulosus histone acetyltransferase MYST2 0.0037 0.0067 0.0098
Brugia malayi hypothetical protein 0.0061 0.0162 0.0239
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0063 0.0168 0.0248
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.01 0.0315 0.0466
Schistosoma mansoni rab6-interacting 0.0031 0.0045 0.0066
Entamoeba histolytica cysteine protease, putative 0.0223 0.0791 0.9312
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0065 0.0178 0.2248
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0083 0.0123
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.0849 0.6358
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Echinococcus multilocularis cathepsin L 0.0129 0.0427 0.0632
Loa Loa (eye worm) hypothetical protein 0.0065 0.0178 0.0265
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0065 0.0178 0.1337
Loa Loa (eye worm) hypothetical protein 0.0053 0.0128 0.019
Echinococcus multilocularis 0.0183 0.0634 0.094
Schistosoma mansoni lipoxygenase 0.0136 0.0452 0.0671
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0223 0.0791 0.5921
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0223 0.0791 0.1173
Brugia malayi cathepsin Z-like cysteine proteinase 0.0065 0.0178 0.0264
Loa Loa (eye worm) hypothetical protein 0.0053 0.0128 0.019
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0027 0.003 0.0044
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.01 0.0315 0.0466
Brugia malayi hypothetical protein 0.0053 0.0128 0.0189
Trypanosoma cruzi major cysteine proteinase, putative 0.0065 0.0178 0.0456
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0038 0.0282
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.0159
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Schistosoma mansoni tyrosine kinase 0.0931 0.3542 0.5261
Schistosoma mansoni tyrosine kinase 0.056 0.2101 0.312
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0129 0.0427 0.0632
Giardia lamblia Cathepsin B precursor 0.0065 0.0178 0.133
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0256 0.0921 0.1368
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0099 0.031 0.046
Schistosoma mansoni hypothetical protein 0.0027 0.0031 0.0044
Echinococcus multilocularis jumonji domain containing protein 0.0027 0.0031 0.0045
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0047 0.0106 0.0158
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0021 0.0252
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0268 0.0396
Echinococcus multilocularis isocitrate dehydrogenase 0.0025 0.0022 0.0031
Schistosoma mansoni tyrosine kinase 0.1752 0.6732 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0033 0.0053 0.0391
Brugia malayi Steroid receptor seven-up type 2 0.0099 0.031 0.046
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0025 0.0022 0.0031
Plasmodium vivax SET domain protein, putative 0.0028 0.0035 0.0424
Brugia malayi hypothetical protein 0.0031 0.0045 0.0066
Giardia lamblia Cathepsin L precursor 0.0065 0.0178 0.133
Plasmodium falciparum ataxin-2 like protein, putative 0.0061 0.0162 0.2038
Onchocerca volvulus 0.0223 0.0791 0.5939
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Onchocerca volvulus 0.0028 0.0035 0.0252
Entamoeba histolytica hypothetical protein 0.0063 0.0168 0.1975
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0223 0.0791 0.5921
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.0106 0.0157
Trypanosoma cruzi PAB1-binding protein , putative 0.0061 0.0162 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0129 0.0427 0.3195
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1028 0.3919 0.5821
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0065 0.0178 0.2103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Giardia lamblia Kinase, CMGC MAPK 0.0041 0.0086 0.0633
Mycobacterium ulcerans dehydrogenase 0.0183 0.0634 0.0614
Echinococcus granulosus mitogen activated protein kinase 3 0.0041 0.0086 0.0125
Loa Loa (eye worm) mbt repeat family protein 0.0032 0.005 0.0074
Schistosoma mansoni jumonji/arid domain-containing protein 0.0024 0.0017 0.0024
Entamoeba histolytica hypothetical protein 0.0065 0.0178 0.2103
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Schistosoma mansoni hypothetical protein 0.01 0.0315 0.0466
Echinococcus granulosus lamin 0.002 0.0002 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0086 0.064
Echinococcus multilocularis RUN 0.0031 0.0045 0.0066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0129 0.0427 0.3104
Onchocerca volvulus 0.0173 0.0595 0.4465
Brugia malayi Cathepsin L-like precursor 0.0064 0.0172 0.0255
Entamoeba histolytica cysteine protease, putative 0.0065 0.0178 0.2103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0065 0.0178 0.1337
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0119 0.0389 0.0577
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0038 0.0096
Entamoeba histolytica hypothetical protein 0.0063 0.0168 0.1975
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0183 0.0634 0.8015
Echinococcus granulosus GPCR family 2 0.01 0.0315 0.0466
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0064 0.0172 0.0256
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0131 0.0435 0.0646
Loa Loa (eye worm) hypothetical protein 0.0099 0.031 0.0461
Schistosoma mansoni cathepsin s 0.0064 0.0172 0.0255
Loa Loa (eye worm) hypothetical protein 0.0099 0.031 0.0461
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0172 0.044
Leishmania major hypothetical protein, conserved 0.0061 0.0162 0.1213
Trypanosoma cruzi cysteine peptidase, putative 0.0129 0.0427 0.1089
Toxoplasma gondii cathepsin CPC2 0.0065 0.0178 0.133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0065 0.0178 0.1337
Brugia malayi intermediate filament protein 0.002 0.0002 0.0001
Brugia malayi nuclear receptor NHR-67 0.0047 0.0106 0.0157
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0175 0.0166
Brugia malayi hypothetical protein 0.0031 0.0045 0.0066
Schistosoma mansoni lamin 0.002 0.0002 0.0001
Schistosoma mansoni thyroid hormone receptor 0.0099 0.031 0.046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0065 0.0178 0.1337
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0175 0.0155
Entamoeba histolytica cysteine proteinase, putative 0.0129 0.0427 0.5025
Echinococcus granulosus histone acetyltransferase KAT2B 0.011 0.0351 0.0519
Onchocerca volvulus 0.0047 0.0106 0.0793
Echinococcus granulosus transcription factor Dp 1 0.0031 0.0045 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0065 0.0178 0.1337
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0065 0.0178 0.133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0099 0.031 0.046
Brugia malayi ShTK domain containing protein 0.0173 0.0595 0.0882
Echinococcus multilocularis 0.0542 0.2031 0.3015
Plasmodium falciparum histone acetyltransferase GCN5 0.003 0.0043 0.0525
Loa Loa (eye worm) hypothetical protein 0.0159 0.0542 0.0806
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Loa Loa (eye worm) hypothetical protein 0.0099 0.031 0.0461
Entamoeba histolytica cysteine proteinase 2 0.0129 0.0427 0.5025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0065 0.0178 0.1337
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.0849 0.6358
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0001
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0047 0.0106 0.0157
Brugia malayi Intermediate filament tail domain containing protein 0.002 0.0002 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0086 0.064
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0065 0.0178 0.0264
Trichomonas vaginalis maltase-glucoamylase, putative 0.0029 0.0038 0.0282
Brugia malayi hypothetical protein 0.0039 0.0078 0.0114
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0038 0.0282
Echinococcus multilocularis thyroid hormone receptor alpha 0.0099 0.031 0.046
Brugia malayi Pre-SET motif family protein 0.0198 0.0693 0.1028
Leishmania major alpha glucosidase II subunit, putative 0.0029 0.0038 0.0282
Echinococcus multilocularis histone acetyltransferase MYST2 0.0037 0.0067 0.0098
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0106 0.0157
Echinococcus granulosus ecdysone induced protein 78C 0.0099 0.031 0.046
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0175 0.0259
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0173 0.0595 0.0882
Brugia malayi conserved hypotetical protein 0.0047 0.0106 0.0157
Brugia malayi Doublecortin family protein 0.0031 0.0045 0.0066
Onchocerca volvulus 0.0173 0.0595 0.4465
Brugia malayi Cathepsin L-like cysteine proteinase 0.0159 0.0542 0.0804
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0129 0.0427 0.1089
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0041 0.0086 0.0218
Trichomonas vaginalis bromodomain-containing protein, putative 0.0033 0.0053 0.0399
Plasmodium falciparum serine repeat antigen 5 0.0065 0.0178 0.2248
Giardia lamblia Cathepsin L-like protease 0.0065 0.0178 0.133
Toxoplasma gondii LsmAD domain-containing protein 0.0061 0.0162 0.1206
Loa Loa (eye worm) hypothetical protein 0.0053 0.0128 0.019
Onchocerca volvulus 0.0076 0.022 0.1644
Schistosoma mansoni microtubule-associated protein tau 0.0656 0.2472 0.3672
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.0038 0.0443
Echinococcus granulosus FTZ F1 alpha 0.0099 0.031 0.046
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0028 0.0035 0.005
Echinococcus multilocularis cathepsin L cysteine protease 0.0223 0.0791 0.1173
Schistosoma mansoni zinc finger protein 0.0047 0.0106 0.0157
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0127 0.0419 0.0621
Echinococcus granulosus intermediate filament protein 0.002 0.0002 0.0001
Schistosoma mansoni alpha-glucosidase 0.0113 0.0364 0.0539
Giardia lamblia Cathepsin B precursor 0.0065 0.0178 0.133
Entamoeba histolytica cysteine protease, putative 0.0065 0.0178 0.2103
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0054 0.0133 0.0198
Echinococcus multilocularis ecdysone induced protein 78C 0.0099 0.031 0.046
Loa Loa (eye worm) hypothetical protein 0.01 0.0315 0.0467
Loa Loa (eye worm) latrophilin receptor protein 2 0.01 0.0315 0.0467
Loa Loa (eye worm) isocitrate dehydrogenase 0.0025 0.0022 0.0032
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0038 0.0282
Schistosoma mansoni tyrosine kinase 0.0942 0.3583 0.5322
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Loa Loa (eye worm) hypothetical protein 0.0183 0.0634 0.0941
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0065 0.0178 0.2248
Trypanosoma cruzi cysteine peptidase, putative 0.0286 0.1036 0.2645
Echinococcus multilocularis cathepsin b 0.1028 0.3919 0.5821
Brugia malayi amine oxidase, flavin-containing family protein 0.0183 0.0634 0.094
Leishmania major cysteine peptidase A (CPA) 0.0223 0.0791 0.5921
Entamoeba histolytica cysteine proteinase, putative 0.0159 0.0542 0.6389
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0032 0.005 0.0073
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0026
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0053 0.0128 0.019
Loa Loa (eye worm) hypothetical protein 0.0064 0.0172 0.0256
Echinococcus granulosus insulin receptor 0.056 0.2101 0.312
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.0849 0.6358
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0099 0.031 0.046
Loa Loa (eye worm) hypothetical protein 0.0064 0.0172 0.0256
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.01 0.0315 0.0466
Schistosoma mansoni cathepsin C 0.0065 0.0178 0.0264
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0113 0.0363 0.0538
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0099 0.031 0.046
Plasmodium vivax importin-beta 2, putative 0.0024 0.0018 0.021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0025 0.0022 0.0031
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.0106 0.0157
Giardia lamblia Cathepsin B precursor 0.0065 0.0178 0.133
Echinococcus multilocularis muscleblind protein 0.0355 0.1304 0.1936
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0099 0.031 0.046
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0037 0.0067 0.0098
Brugia malayi Cathepsin L-like precursor 0.0223 0.0791 0.1173
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0099 0.031 0.0461
Schistosoma mansoni cathepsin B (C01 family) 0.0065 0.0178 0.0264
Brugia malayi mbt repeat family protein 0.0032 0.005 0.0073
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0065 0.0178 0.2248
Brugia malayi Nuclear hormone receptor-like 1 0.0099 0.031 0.046
Loa Loa (eye worm) hypothetical protein 0.0099 0.031 0.0461
Entamoeba histolytica cysteine protease, putative 0.0065 0.0178 0.2103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Schistosoma mansoni retinoic acid receptor RXR 0.0099 0.031 0.046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Onchocerca volvulus 0.0173 0.0595 0.4465
Plasmodium vivax vivapain-2 0.0223 0.0791 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0223 0.0791 0.5921
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Plasmodium vivax vivapain-2 0.0223 0.0791 1
Echinococcus multilocularis peregrin 0.0023 0.0012 0.0016
Giardia lamblia Hypothetical protein 0.0065 0.0178 0.133
Brugia malayi mbt repeat family protein 0.0032 0.005 0.0073
Echinococcus granulosus cathepsin l1 0.0223 0.0791 0.1173
Trypanosoma brucei protein kinase, putative 0.0041 0.0086 0.0515
Plasmodium vivax hypothetical protein, conserved 0.0183 0.0634 0.8015
Echinococcus multilocularis cathepsin L cysteine protease 0.0223 0.0791 0.1173
Plasmodium falciparum serine repeat antigen 7 0.0065 0.0178 0.2248
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0086 0.0125
Plasmodium falciparum serine repeat antigen 6 0.0065 0.0178 0.2248
Giardia lamblia Cysteine protease 0.0065 0.0178 0.133
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0025 0.0022 0.0033
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Plasmodium falciparum cysteine proteinase falcipain 3 0.0223 0.0791 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0223 0.0791 0.1174
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0054 0.0133 0.1568
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0099 0.031 0.046
Giardia lamblia Encystation-specific protease 0.0065 0.0178 0.133
Brugia malayi Papain family cysteine protease containing protein 0.0129 0.0427 0.0632
Onchocerca volvulus Huntingtin homolog 0.0192 0.0672 0.5046
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0311 0.1131 0.168
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0099 0.031 0.2328
Giardia lamblia Cathepsin B precursor 0.0363 0.1335 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0065 0.0178 0.2103
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0065 0.0178 0.0264
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0099 0.031 0.046
Brugia malayi Pre-SET motif family protein 0.0028 0.0035 0.005
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0063 0.0168 0.1975
Schistosoma mansoni tar DNA-binding protein 0.0311 0.1131 0.1679
Brugia malayi TAR-binding protein 0.0311 0.1131 0.1679
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0063 0.0168 0.0248
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0053 0.0128 0.0189
Brugia malayi Importin beta-1 subunit 0.0024 0.0018 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0099 0.031 0.0461
Loa Loa (eye worm) hypothetical protein 0.0053 0.0128 0.019
Schistosoma mansoni jumonji/arid domain-containing protein 0.0024 0.0017 0.0024
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0065 0.0178 0.133
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.0051
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0025 0.0022 0.0031
Loa Loa (eye worm) intermediate filament protein 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Brugia malayi Cathepsin L-like precursor 0.0223 0.0791 0.1173
Schistosoma mansoni sex comb on midleg homolog 0.0032 0.005 0.0073
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0223 0.0791 0.1173
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0223 0.0791 1
Echinococcus granulosus lysosomal alpha glucosidase 0.0131 0.0435 0.0644
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0099 0.031 0.046
Brugia malayi cathepsin Z-like cysteine proteinase 0.0065 0.0178 0.0264
Onchocerca volvulus 0.0159 0.0542 0.4072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0099 0.031 0.0461
Loa Loa (eye worm) hypothetical protein 0.0065 0.0178 0.0265
Trypanosoma brucei glucosidase, putative 0.0029 0.0038 0.0151
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0223 0.0791 0.1174
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0035 0.005
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0021 0.0149
Echinococcus multilocularis cathepsin L 0.0065 0.0178 0.0264
Plasmodium falciparum serine repeat antigen 9 0.0065 0.0178 0.2248
Schistosoma mansoni hypothetical protein 0.01 0.0315 0.0466
Echinococcus granulosus jumonji domain containing protein 0.0027 0.0031 0.0045
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0116 0.0376 0.0356
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0065 0.0178 0.0265
Brugia malayi Cathepsin L-like precursor 0.0223 0.0791 0.1173
Echinococcus granulosus mitogen activated protein kinase 0.0041 0.0086 0.0125
Brugia malayi Papain family cysteine protease containing protein 0.0065 0.0178 0.0264
Schistosoma mansoni hypothetical protein 0.0063 0.0168 0.0248
Loa Loa (eye worm) hypothetical protein 0.0217 0.0768 0.114
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0099 0.031 0.046
Brugia malayi Protein kinase domain containing protein 0.056 0.2101 0.312
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.0849 0.6358
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.01
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0223 0.0791 0.5921
Plasmodium falciparum serine repeat antigen 1 0.0065 0.0178 0.2248
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.0176 0.0259
Echinococcus multilocularis lysosomal alpha glucosidase 0.0131 0.0435 0.0644
Plasmodium falciparum serine repeat antigen 4 0.0065 0.0178 0.2248
Schistosoma mansoni nuclear receptor nhr-48 0.0047 0.0106 0.0157
Plasmodium vivax unspecified product 0.0064 0.0172 0.2171
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0363 0.1335 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0028 0.0035 0.005
Giardia lamblia Cathepsin L precursor 0.0065 0.0178 0.133
Echinococcus granulosus tumor protein p63 0.0321 0.1172 0.174
Brugia malayi hypothetical protein 0.0183 0.0634 0.094
Onchocerca volvulus 0.01 0.0313 0.2345
Leishmania major cathepsin L-like protease 0.0286 0.1036 0.7762
Echinococcus multilocularis tar DNA binding protein 0.0311 0.1131 0.1679
Loa Loa (eye worm) hypothetical protein 0.0183 0.0634 0.0941
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0099 0.031 0.046
Trypanosoma cruzi cysteine proteinase, putative 0.0129 0.0427 0.1089
Trichomonas vaginalis set domain proteins, putative 0.0225 0.0799 0.5983
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0065 0.0178 0.0264
Toxoplasma gondii isocitrate dehydrogenase 0.0025 0.0022 0.0157
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0183 0.0634 0.8015
Loa Loa (eye worm) hypothetical protein 0.0099 0.031 0.0461
Schistosoma mansoni loxhd1 0.0031 0.0045 0.0066
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0065 0.0178 0.2248
Echinococcus granulosus neuropeptide s receptor 0.075 0.2839 0.4216
Echinococcus multilocularis lamin 0.002 0.0002 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0065 0.0178 0.0264
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0183 0.0634 0.8015
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.056 0.2101 0.312
Brugia malayi cathepsin L-like cysteine proteinase 0.0065 0.0178 0.0264
Plasmodium falciparum ataxin-2 like protein, putative 0.0061 0.0162 0.2038
Giardia lamblia Cathepsin B precursor 0.0363 0.1335 1
Schistosoma mansoni hypothetical protein 0.0217 0.0768 0.1139
Echinococcus granulosus SAM and MBT domain containing protein 0.0032 0.005 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Schistosoma mansoni amine oxidase 0.0183 0.0634 0.094
Loa Loa (eye worm) hypothetical protein 0.0159 0.0542 0.0806
Brugia malayi RNA recognition motif domain containing protein 0.0311 0.1131 0.1679
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0047 0.0106 0.0157
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0041 0.0086 0.0633
Loa Loa (eye worm) MBCTL1 0.0037 0.0067 0.01
Loa Loa (eye worm) TAR-binding protein 0.0311 0.1131 0.168
Schistosoma mansoni tar DNA-binding protein 0.0311 0.1131 0.1679
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0038 0.0282
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0037 0.0067 0.0098
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0223 0.0791 0.5921
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0175 0.0259
Loa Loa (eye worm) nuclear hormone receptor 0.0047 0.0106 0.0158
Giardia lamblia Cathepsin L precursor 0.0065 0.0178 0.133
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0033 0.0053 0.0399
Leishmania major cathepsin L-like protease 0.0223 0.0791 0.5921
Trypanosoma cruzi cysteine proteinase, putative 0.0129 0.0427 0.1089
Echinococcus multilocularis nuclear receptor nhr 48 0.0047 0.0106 0.0157
Echinococcus multilocularis cathepsin b 0.1028 0.3919 0.5821
Onchocerca volvulus Huntingtin homolog 0.0192 0.0672 0.5046
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0183 0.0634 0.0614
Entamoeba histolytica cysteine proteinase, putative 0.0223 0.0791 0.9312
Onchocerca volvulus Bile acid receptor homolog 0.0099 0.031 0.2328
Plasmodium falciparum LCCL domain-containing protein 0.0031 0.0045 0.0561
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0172 0.044
Entamoeba histolytica cysteine proteinase 1, putative 0.0129 0.0427 0.5025
Toxoplasma gondii cathepsin B 0.0363 0.1335 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0175 0.0155
Echinococcus granulosus snurportin 1 0.0256 0.0921 0.1367
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0065 0.0178 0.1337
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0065 0.0178 0.2248
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0047 0.0106 0.0157
Giardia lamblia Cathepsin B precursor 0.0065 0.0178 0.133
Giardia lamblia Cathepsin L precursor 0.0065 0.0178 0.133
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0183 0.0634 0.094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Brugia malayi acetyltransferase, GNAT family protein 0.0113 0.0363 0.0538
Brugia malayi hypothetical protein 0.0362 0.133 0.1975
Schistosoma mansoni polycystin 1-related 0.0031 0.0045 0.0066
Onchocerca volvulus Cathepsin F homolog 0.0223 0.0791 0.5939
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0128 0.0189
Brugia malayi fibroinase precursor 0.0065 0.0178 0.0264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0223 0.0791 0.5921
Trypanosoma brucei PAB1-binding protein , putative 0.0061 0.0162 0.1095
Echinococcus multilocularis SAM and MBT domain containing protein 0.0032 0.005 0.0073
Toxoplasma gondii preprocathepsin c precursor, putative 0.0065 0.0178 0.133
Onchocerca volvulus 0.0183 0.0634 0.476
Schistosoma mansoni sex comb on midleg homolog 0.0032 0.005 0.0073
Plasmodium falciparum protoporphyrinogen oxidase 0.0183 0.0634 0.8015
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0054 0.0133 0.0196
Onchocerca volvulus 0.0065 0.0178 0.1335
Schistosoma mansoni tyrosine kinase 0.0942 0.3583 0.5322
Echinococcus granulosus importin subunit beta 1 0.0024 0.0018 0.0025
Giardia lamblia Hypothetical protein 0.0065 0.0178 0.133
Toxoplasma gondii HEAT repeat-containing protein 0.0024 0.0018 0.0124
Loa Loa (eye worm) hypothetical protein 0.0362 0.133 0.1976
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1028 0.3919 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0065 0.0178 0.0264
Loa Loa (eye worm) hypothetical protein 0.0065 0.0178 0.0265
Entamoeba histolytica cysteine protease, putative 0.0065 0.0178 0.2103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0099 0.031 0.0461
Mycobacterium tuberculosis Possible oxidoreductase 0.0183 0.0634 0.0661
Echinococcus granulosus cysteine protease 0.0129 0.0427 0.0632
Echinococcus granulosus cathepsin l cysteine peptidase 0.0223 0.0791 0.1173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0136 0.0452 0.0671
Schistosoma mansoni intermediate filament proteins 0.002 0.0002 0.0001
Onchocerca volvulus 0.0031 0.0045 0.0333
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1028 0.3919 0.5821
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0065 0.0178 0.2248
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0099 0.031 0.046
Brugia malayi Muscleblind-like protein 0.0355 0.1304 0.1936
Schistosoma mansoni cathepsin F (C01 family) 0.0223 0.0791 0.1173
Loa Loa (eye worm) hypothetical protein 0.0183 0.0634 0.0941
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0001 0.0001
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0029 0.0038 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0065 0.0178 0.1337
Brugia malayi jmjC domain containing protein 0.0024 0.0017 0.0024
Brugia malayi Cathepsin L-like precursor 0.0223 0.0791 0.1173
Schistosoma mansoni tar DNA-binding protein 0.0311 0.1131 0.1679
Onchocerca volvulus 0.0362 0.133 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0173 0.0595 0.0882
Onchocerca volvulus 0.0088 0.0268 0.2007
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0363 0.1335 1
Loa Loa (eye worm) hypothetical protein 0.0192 0.0672 0.0998
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0175 0.1312
Leishmania major cathepsin L-like protease 0.0286 0.1036 0.7762
Schistosoma mansoni hypothetical protein 0.0648 0.2441 0.3625
Trypanosoma cruzi major cysteine proteinase, putative 0.0129 0.0424 0.1083
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1028 0.3919 0.5821
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0268 0.0396
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0065 0.0178 0.0264
Schistosoma mansoni thyroid hormone receptor 0.0099 0.031 0.046
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.0106 0.0793
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Loa Loa (eye worm) hypothetical protein 0.1028 0.3919 0.5821
Echinococcus granulosus tar DNA binding protein 0.0311 0.1131 0.1679
Echinococcus multilocularis protoporphyrinogen oxidase 0.0183 0.0634 0.094
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0065 0.0178 0.1337
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0363 0.1335 0.3407
Echinococcus granulosus Polycystic kidney disease protein 0.0031 0.0045 0.0066
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0035 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0065 0.0178 0.1337
Brugia malayi MAP kinase sur-1 0.0041 0.0086 0.0125
Loa Loa (eye worm) nuclear receptor NHR-67 0.0047 0.0106 0.0158
Brugia malayi ecdysteroid receptor 0.0099 0.031 0.046
Echinococcus granulosus cathepsin L cysteine proteinase 0.0223 0.0791 0.1173
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0065 0.0178 0.2248
Echinococcus granulosus peregrin 0.0023 0.0012 0.0016
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0037 0.0067 0.0098
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0054 0.0133 0.0196
Echinococcus granulosus RUN 0.0031 0.0045 0.0066
Brugia malayi RNA binding protein 0.0311 0.1131 0.1679
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0021 0.0149
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0318 0.1158 0.172
Mycobacterium tuberculosis Conserved hypothetical protein 0.0183 0.0634 0.0661
Brugia malayi tailless protein 0.0047 0.0106 0.0157
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0067
Brugia malayi Papain family cysteine protease containing protein 0.0129 0.0427 0.0632
Leishmania major UDP-galactopyranose mutase 0.0183 0.0634 0.4747
Brugia malayi nuclear receptor NHR-88 0.0047 0.0106 0.0157
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0106 0.0157
Trypanosoma cruzi cruzipain precursor, putative 0.0286 0.1036 0.2645
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0025 0.0022 0.0031
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0129 0.0427 0.3195
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0065 0.0178 0.2248
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.0106 0.0793
Trypanosoma cruzi cysteine peptidase, putative 0.0223 0.0791 0.2017
Brugia malayi cathepsin F-like cysteine proteinase 0.0065 0.0178 0.0264
Echinococcus granulosus muscleblind protein 0.0355 0.1304 0.1936
Onchocerca volvulus 0.0223 0.0791 0.5939
Echinococcus granulosus neutral alpha glucosidase AB 0.0029 0.0038 0.0054
Onchocerca volvulus 0.0099 0.031 0.2328
Brugia malayi cathepsin L precursor 0.0065 0.0178 0.0264
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0223 0.0791 0.5921
Brugia malayi Cathepsin L-like precursor 0.0159 0.0542 0.0804
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0065 0.0178 0.0264
Schistosoma mansoni hypothetical protein 0.0648 0.2441 0.3625
Trypanosoma cruzi cysteine protease, putative 0.0129 0.0427 0.1089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0067
Plasmodium falciparum serine repeat antigen 8 0.0065 0.0178 0.2248
Brugia malayi hypothetical protein 0.0053 0.0128 0.0189
Loa Loa (eye worm) hypothetical protein 0.0088 0.0268 0.0398
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0029 0.0038 0.0274
Trypanosoma cruzi cysteine peptidase, putative 0.0286 0.1036 0.2645
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0038 0.0282
Loa Loa (eye worm) tyrosinase 1 0.0173 0.0595 0.0883
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0942 0.3583 0.5322
Brugia malayi hypothetical protein 0.0192 0.0672 0.0997
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0175 0.0155
Brugia malayi nuclear hormone receptor family member odr-7 0.0047 0.0106 0.0157
Trichomonas vaginalis sucrase-isomaltase, putative 0.0029 0.0038 0.0282
Schistosoma mansoni lamin 0.002 0.0002 0.0001
Echinococcus granulosus cathepsin b 0.1028 0.3919 0.5821
Leishmania major cathepsin L-like protease 0.0223 0.0791 0.5921
Chlamydia trachomatis protoporphyrinogen oxidase 0.0183 0.0634 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Echinococcus granulosus geminin 0.0648 0.2441 0.3625
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0159 0.0542 0.4062
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0238 0.0849 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Echinococcus multilocularis epidermal growth factor receptor 0.0942 0.3583 0.5322
Plasmodium vivax serine-repeat antigen (SERA) 0.0065 0.0178 0.2248
Entamoeba histolytica cysteine proteinase, putative 0.0129 0.0427 0.5025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0099 0.031 0.046
Loa Loa (eye worm) hypothetical protein 0.0173 0.0595 0.0883
Loa Loa (eye worm) fibroinase 0.0223 0.0791 0.1174
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0086 0.064
Brugia malayi Nuclear hormone receptor E75 0.0047 0.0106 0.0157
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0021 0.5
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0025 0.0022 0.0031
Giardia lamblia Cysteine protease 0.0065 0.0178 0.133
Echinococcus granulosus cathepsin L 0.0065 0.0178 0.0264
Echinococcus granulosus epidermal growth factor receptor 0.1752 0.6732 1
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0173 0.0595 0.0882
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.01 0.0315 0.0466
Loa Loa (eye worm) hypothetical protein 0.0099 0.031 0.0461
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0065 0.0178 0.0265
Brugia malayi steroid hormone receptor 0.0099 0.031 0.046
Plasmodium vivax serine-repeat antigen (SERA) 0.0065 0.0178 0.2248
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0053 0.0128 0.0189
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0065 0.0178 0.2248
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0133 0.034
Brugia malayi nuclear hormone receptor family member nhr-6 0.0047 0.0106 0.0157
Echinococcus granulosus polycomb protein SCMH1 0.0032 0.005 0.0073
Brugia malayi isocitrate dehydrogenase 0.0025 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0183 0.0634 0.0941
Echinococcus granulosus nuclear receptor nhr 48 0.0047 0.0106 0.0157
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.0849 0.6358
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0223 0.0791 0.5921
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0363 0.1335 0.1982
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0129 0.0427 0.3104
Echinococcus multilocularis lamin dm0 0.002 0.0002 0.0001
Giardia lamblia Cathepsin B precursor 0.0363 0.1335 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0038 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0065 0.0178 0.1337
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0099 0.031 0.046
Brugia malayi nuclear receptor RXR 0.0053 0.0128 0.0189
Brugia malayi Isocitrate dehydrogenase 0.0025 0.0022 0.0031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0099 0.031 0.046
Trypanosoma cruzi cysteine peptidase, putative 0.0286 0.1036 0.2645
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.0038 0.0054
Echinococcus multilocularis neuropeptide receptor A26 0.075 0.2839 0.4216
Onchocerca volvulus 0.002 0.0002 0.0004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0318 0.1158 0.1719
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0033 0.0053 0.0391
Echinococcus multilocularis microtubule associated protein 2 0.0656 0.2472 0.3672
Loa Loa (eye worm) hypothetical protein 0.0099 0.031 0.0461
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0099 0.031 0.046
Onchocerca volvulus 0.0047 0.0106 0.0793
Trypanosoma cruzi UDP-galactopyranose mutase 0.0183 0.0634 0.1618
Giardia lamblia Cathepsin L-like protease 0.0065 0.0178 0.133
Schistosoma mansoni hypothetical protein 0.0196 0.0688 0.102
Echinococcus multilocularis mitogen activated protein kinase 3 0.0041 0.0086 0.0125
Schistosoma mansoni tyrosine kinase 0.0931 0.3542 0.5261
Leishmania major cathepsin L-like protease 0.0223 0.0791 0.5921
Loa Loa (eye worm) steroid hormone receptor 0.0099 0.031 0.0461
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0041 0.0086 0.064
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0198 0.0693 0.1029
Echinococcus granulosus lamin dm0 0.002 0.0002 0.0001
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0025 0.0022 0.0265
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.0038 0.0443
Schistosoma mansoni cathepsin F (C01 family) 0.0223 0.0791 0.1173
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0025 0.0022 0.0031
Onchocerca volvulus 0.0223 0.0791 0.5939
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0025 0.0022 0.0164
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0129 0.0427 0.0632
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0025 0.0022 0.0001
Entamoeba histolytica cysteine protease, putative 0.0065 0.0178 0.2103
Loa Loa (eye worm) hypothetical protein 0.0159 0.0542 0.0806
Giardia lamblia Cysteine protease 0.0065 0.0178 0.133
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0222 0.0788 0.2012
Loa Loa (eye worm) hypothetical protein 0.0318 0.1158 0.172
Schistosoma mansoni nuclear receptor 0.0047 0.0106 0.0157
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0099 0.031 0.046
Schistosoma mansoni coup transcription factor 0.0099 0.031 0.046
Brugia malayi latrophilin 2 splice variant baaae 0.0217 0.0768 0.1139
Entamoeba histolytica cysteine proteinase, putative 0.0129 0.0427 0.5025
Brugia malayi photoreceptor-specific nuclear receptor 0.0099 0.031 0.046
Echinococcus multilocularis neutral alpha glucosidase AB 0.0029 0.0038 0.0054
Echinococcus multilocularis snurportin 1 0.0256 0.0921 0.1367
Entamoeba histolytica cysteine protease, putative 0.0129 0.0427 0.5025
Loa Loa (eye worm) TK/INSR protein kinase 0.056 0.2101 0.3121
Loa Loa (eye worm) ctsf protein 0.0223 0.0791 0.1174
Brugia malayi Nuclear hormone receptor E75 0.0047 0.0106 0.0157
Loa Loa (eye worm) hypothetical protein 0.0065 0.0178 0.0265
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0021 0.0157
Plasmodium vivax unspecified product 0.0065 0.0178 0.2248
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0223 0.0791 0.5921
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0053 0.0128 0.0189
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0099 0.031 0.046
Echinococcus multilocularis lysine specific demethylase 5A 0.0024 0.0017 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0129 0.0427 0.5025
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0065 0.0178 0.1337
Loa Loa (eye worm) ShTK domain-containing protein 0.0173 0.0595 0.0883
Plasmodium falciparum serine repeat antigen 3 0.0065 0.0178 0.2248
Echinococcus multilocularis lipoxygenase domain containing protein 0.0031 0.0045 0.0066
Schistosoma mansoni RAR-like nuclear receptor 0.0099 0.031 0.046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0286 0.1036 0.7732
Loa Loa (eye worm) hypothetical protein 0.0047 0.0106 0.0158
Loa Loa (eye worm) TK/EGFR protein kinase 0.1752 0.6732 1
Echinococcus multilocularis transcription factor Dp 1 0.0031 0.0045 0.0066
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0099 0.031 0.046
Schistosoma mansoni rab6-interacting 0.0031 0.0045 0.0066
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.0176 0.0259
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0116 0.0376 0.5793
Schistosoma mansoni jumonji domain containing protein 0.0051 0.0124 0.0183
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0099 0.031 0.046
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0099 0.031 0.046
Plasmodium vivax unspecified product 0.0129 0.0427 0.539
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0099 0.031 0.0461
Brugia malayi nuclear hormone receptor 0.0047 0.0106 0.0157
Toxoplasma gondii cathepsin CPL 0.0223 0.0791 0.5918
Schistosoma mansoni hypothetical protein 0.01 0.0315 0.0466
Onchocerca volvulus 0.0173 0.0595 0.4465
Plasmodium falciparum importin beta, putative 0.0024 0.0018 0.021
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0268 0.0396
Echinococcus multilocularis FTZ F1 alpha 0.0099 0.031 0.046
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0099 0.031 0.046
Schistosoma mansoni tyrosine kinase 0.0931 0.3542 0.5261
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0041 0.0086 0.0127
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0064 0.0172 0.0255
Trypanosoma brucei cysteine peptidase C (CPC) 0.0363 0.1335 1
Schistosoma mansoni importin beta-1 0.0024 0.0018 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0311 0.1131 0.1679
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0033 0.0053 0.0661
Entamoeba histolytica cysteine protease, putative 0.0065 0.0178 0.2103
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0099 0.031 0.046
Loa Loa (eye worm) hypothetical protein 0.0192 0.0672 0.0998
Schistosoma mansoni alpha glucosidase 0.0029 0.0038 0.0054
Entamoeba histolytica hypothetical protein 0.0063 0.0168 0.1975
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0099 0.031 0.046
Onchocerca volvulus 0.0047 0.0107 0.0796
Schistosoma mansoni myelin transcription factor 1 myt1 0.0037 0.0067 0.0098
Onchocerca volvulus 0.0223 0.0791 0.5939
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.0106 0.0157
Echinococcus multilocularis lipoxygenase domain containing protein 0.0031 0.0045 0.0066
Loa Loa (eye worm) cysteine protease 0.0223 0.0791 0.1174
Giardia lamblia Cathepsin B precursor 0.0065 0.0178 0.133
Brugia malayi Glycosyl hydrolases family 31 protein 0.0131 0.0435 0.0644
Plasmodium vivax multidomain scavenger receptor, putative 0.0031 0.0045 0.0561
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0038 0.0096
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.0849 0.6358
Echinococcus granulosus cathepsin b 0.1028 0.3919 0.5821
Schistosoma mansoni hypothetical protein 0.01 0.0315 0.0466
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0025 0.0022 0.0265
Echinococcus multilocularis Polycystic kidney disease protein 0.0031 0.0045 0.0066
Giardia lamblia Fructose-bisphosphate aldolase 0.0238 0.0849 0.6355
Schistosoma mansoni hypothetical protein 0.0031 0.0045 0.0066
Schistosoma mansoni tar DNA-binding protein 0.0311 0.1131 0.1679
Onchocerca volvulus Protein ultraspiracle homolog 0.0099 0.031 0.2328
Loa Loa (eye worm) hypothetical protein 0.0065 0.0178 0.0265
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0099 0.031 0.046
Schistosoma mansoni nuclear hormone receptor 0.0099 0.031 0.046
Giardia lamblia Cysteine protease 0.0065 0.0178 0.133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0791 0.5921
Echinococcus multilocularis polycomb protein SCMH1 0.0032 0.005 0.0073

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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