Detailed information for compound 985312

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 231.29 | Formula: C14H17NO2
  • H donors: 1 H acceptors: 2 LogP: 2.49 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C(=O)NC(C)(C)C)/C=C/c1ccccc1
  • InChi: 1S/C14H17NO2/c1-14(2,3)15-13(17)12(16)10-9-11-7-5-4-6-8-11/h4-10H,1-3H3,(H,15,17)/b10-9+
  • InChiKey: PWSSQPFAEQTBMD-MDZDMXLPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0056 0.0685
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0463 0.2299 0.3385
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0018 0.0015 0.0017
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.1237 0.319
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0097 0.0403
Trichomonas vaginalis sugar transporter, putative 0.0144 0.0661 0.2861
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0146 0.021
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0463 0.2299 0.3385
Echinococcus granulosus solute carrier family 22 0.0065 0.0259 0.0376
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0026 0.0058 0.2114
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0038 0.0088
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0142 0.0652 0.0956
Echinococcus multilocularis histidyl tRNA synthetase 0.0016 0.0005 0.0002
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0139 0.0637 0.1174
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0065 0.0259 1
Brugia malayi F/Y-rich N-terminus family protein 0.004 0.013 0.0326
Entamoeba histolytica hypothetical protein 0.0304 0.148 0.2739
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0026 0.0058 0.0715
Echinococcus multilocularis GPCR, family 2 0.0102 0.0447 0.0654
Schistosoma mansoni hypothetical protein 0.1339 0.6783 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0139 0.0637 0.0939
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0097 0.0403
Schistosoma mansoni neuropeptide receptor 0.0015 0.0004 0.0006
Toxoplasma gondii transporter, major facilitator family protein 0.0065 0.0259 0.0383
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0832 0.3605
Brugia malayi TAR-binding protein 0.0073 0.0298 0.076
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0026 0.0058 0.0262
Mycobacterium ulcerans hypothetical protein 0.0023 0.0043 0.0848
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0142 0.0652 0.0648
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0785 0.3403
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0004 0.0006
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0023 0.0045
Mycobacterium ulcerans integral membrane transport protein 0.0065 0.0259 0.5643
Mycobacterium tuberculosis Conserved protein 0.0039 0.0124 0.0903
Mycobacterium leprae Probable lipase LipE 0.0039 0.0124 0.1368
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Trypanosoma brucei sugar transporter, putative 0.0065 0.0259 0.3384
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0034 0.0127
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0088
Leishmania major hypothetical protein, conserved 0.0023 0.0043 0.0508
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0026 0.0058 0.1193
Trypanosoma brucei histidyl-tRNA synthetase 0.0016 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0022 0.0038 0.0056
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0124 0.0183
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0006
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0166 0.0775 0.1143
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0016 0.0007 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0097 0.0403
Mycobacterium ulcerans hypothetical protein 0.0026 0.0056 0.1142
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0142 0.0652 0.0977
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0124 0.0903
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0049
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0124 0.0521
Brugia malayi CHD4 protein 0.0018 0.0015 0.0029
Leishmania major hypothetical protein, conserved 0.0039 0.0124 0.1592
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.0785 0.6345
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0018 0.0015 0.0023
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0047 0.0182
Schistosoma mansoni glucose transporter 0.0065 0.0259 0.0381
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0049
Schistosoma mansoni aspartyl-tRNA synthetase 0.0016 0.0005 0.0007
Onchocerca volvulus Alhambra homolog 0.0031 0.0085 0.0655
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0056 0.0326
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0175 0.0252
Onchocerca volvulus 0.0065 0.0259 0.2067
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0056 0.0134
Schistosoma mansoni glycyl-tRNA synthetase 0.0026 0.0058 0.0086
Entamoeba histolytica hypothetical protein 0.0103 0.0455 0.0835
Leishmania major hypothetical protein, conserved 0.0065 0.0259 0.3384
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0065 0.0259 0.3384
Trypanosoma cruzi sugar transporter, putative 0.0065 0.0259 0.3384
Loa Loa (eye worm) hypothetical protein 0.0031 0.0085 0.0209
Schistosoma mansoni hypothetical protein 0.0102 0.0447 0.0659
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0057 0.0217 0.0551
Onchocerca volvulus 0.0065 0.0259 0.2067
Trichomonas vaginalis glucose transporter, putative 0.0144 0.0661 0.2861
Schistosoma mansoni hypothetical protein 0.1069 0.5401 0.7962
Plasmodium vivax threonine--tRNA ligase, putative 0.0026 0.0058 0.0054
Brugia malayi SET domain containing protein 0.0016 0.0005 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0652 0.0961
Loa Loa (eye worm) hypothetical protein 0.0113 0.0504 0.1292
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0016 0.0005 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0679 0.0996
Plasmodium falciparum protein kinase 7 0.1309 0.6632 0.663
Onchocerca volvulus 0.0065 0.0259 0.2067
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0091 0.0389 0.1677
Schistosoma mansoni amine GPCR 0.0015 0.0004 0.0006
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0142 0.0652 0.0977
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0124 0.0521
Schistosoma mansoni hypothetical protein 0.0053 0.0197 0.029
Schistosoma mansoni aspartyl-tRNA synthetase 0.0016 0.0005 0.0007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0322 0.1575 0.4067
Giardia lamblia Prolyl-tRNA synthetase 0.0139 0.0637 0.1174
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0038 0.005
Leishmania major lysyl-tRNA synthetase, putative 0.0103 0.0455 0.5997
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0047 0.0182
Brugia malayi Sugar transporter family protein 0.0065 0.0259 0.0659
Schistosoma mansoni protein kinase 0.0142 0.0652 0.0961
Plasmodium falciparum lysine--tRNA ligase 0.0103 0.0455 0.045
Schistosoma mansoni hypothetical protein 0.022 0.1053 0.1552
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0056 0.0685
Brugia malayi beta-lactamase 0.0039 0.0124 0.0311
Echinococcus multilocularis cpg binding protein 0.0099 0.0434 0.0634
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0139 0.0637 0.2756
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0034 0.0127
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0026 0.0058 0.0715
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0162 0.0755 0.1132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0004 0.0006
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0139 0.0637 0.0934
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0134
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0004 0.0006
Echinococcus granulosus histone acetyltransferase KAT2B 0.0161 0.0751 0.1102
Brugia malayi jmjC domain containing protein 0.0102 0.0449 0.1151
Schistosoma mansoni aspartyl-tRNA synthetase 0.0016 0.0005 0.0007
Schistosoma mansoni ap endonuclease 0.0021 0.0035 0.0051
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0016 0.0005 0.0002
Onchocerca volvulus 0.0039 0.0124 0.0974
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0056 0.0095
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0146 0.0215
Brugia malayi jmjC domain containing protein 0.0043 0.0146 0.0367
Giardia lamblia Hexose transporter 0.0065 0.0259 0.0471
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0035 0.0402
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0139 0.0637 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0132 0.0602 0.0883
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0038 0.0033
Brugia malayi Major Facilitator Superfamily protein 0.0065 0.0259 0.0659
Schistosoma mansoni aspartyl-tRNA synthetase 0.0016 0.0005 0.0007
Brugia malayi Latrophilin receptor protein 2 0.0102 0.0447 0.1146
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0035 0.067
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0016 0.0005 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0034 0.0127
Onchocerca volvulus 0.0039 0.0124 0.0974
Plasmodium falciparum calcium-dependent protein kinase 4 0.0142 0.0652 0.0648
Mycobacterium tuberculosis Conserved protein 0.0039 0.0124 0.0903
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0102 0.0447 0.0654
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0259 0.1107
Brugia malayi CXXC zinc finger family protein 0.0094 0.0406 0.1041
Loa Loa (eye worm) hypothetical protein 0.0039 0.0124 0.0311
Onchocerca volvulus 0.0065 0.0259 0.2067
Plasmodium falciparum calcium-dependent protein kinase 5 0.0142 0.0652 0.0648
Plasmodium falciparum mitogen-activated protein kinase 2 0.0749 0.3761 0.3758
Leishmania major hypothetical protein, conserved 0.0023 0.0043 0.0508
Onchocerca volvulus 0.0065 0.0259 0.2067
Brugia malayi MH2 domain containing protein 0.0134 0.0611 0.157
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0085 0.0125
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0004 0.0006
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0099 0.0143
Trypanosoma cruzi hexose transporter, putative 0.0079 0.0327 0.4299
Toxoplasma gondii anticodon binding domain-containing protein 0.0016 0.0005 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0785 0.3403
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0004 0.0006
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0016 0.0005 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0034 0.0127
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Schistosoma mansoni lysyl-tRNA synthetase 0.0103 0.0455 0.067
Brugia malayi Sugar transporter family protein 0.0463 0.2299 0.594
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0026 0.0058 0.008
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0088 0.0375 0.5587
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0158 0.0666
Giardia lamblia DNA repair protein RAD52 0.1067 0.5391 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0139 0.0637 0.1638
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0036 0.0107 0.0158
Plasmodium vivax CDK-related protein kinase 6, putative 0.1967 1 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0199 0.0505
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0051 0.0069
Trypanosoma brucei THT1 - hexose transporter, putative 0.0144 0.0661 0.8747
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0124 0.1592
Echinococcus multilocularis solute carrier family 22 0.0065 0.0259 0.0376
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0311 0.0793
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0038 0.005
Schistosoma mansoni chromobox protein 0.0075 0.0311 0.0458
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Echinococcus granulosus solute carrier family 22 0.0065 0.0259 0.0376
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0124 0.0903
Echinococcus granulosus RUN 0.0022 0.0038 0.005
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0035 0.0131
Plasmodium falciparum phd finger protein, putative 0.0031 0.0085 0.008
Leishmania major glucose transporter, lmgt3 0.0144 0.0661 0.8747
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0085 0.0119
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0147 0.0679 0.1748
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0785 0.3403
Echinococcus granulosus calcium dependent protein kinase 0.0133 0.0607 0.0889
Entamoeba histolytica hypothetical protein 0.0036 0.0107 0.019
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0449 0.0656
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0004 0.0006
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0154 0.0277
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0162 0.0755 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.008 0.0112
Schistosoma mansoni sugar transporter 0.0065 0.0259 0.0381
Onchocerca volvulus 0.0022 0.0038 0.0276
Treponema pallidum prolyl-tRNA synthetase 0.0049 0.0176 1
Brugia malayi hypothetical protein 0.0065 0.0259 0.0659
Echinococcus granulosus neuropeptide s receptor 0.047 0.2333 0.3435
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0023 0.0018
Echinococcus multilocularis neuropeptide receptor A26 0.047 0.2333 0.3435
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0039 0.0147
Toxoplasma gondii sugar transporter ST3 0.0065 0.0259 0.0383
Trypanosoma cruzi glucose transporter, putative 0.0065 0.0259 0.3384
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Trypanosoma brucei glucose transporter, putative 0.0144 0.0661 0.8747
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0001
Leishmania major glucose transporter, lmgt1 0.0144 0.0661 0.8747
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0056 0.1142
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0065 0.0259 0.5643
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0043 0.0214
Loa Loa (eye worm) hypothetical protein 0.0139 0.0637 0.1638
Onchocerca volvulus 0.0046 0.0162 0.1285
Echinococcus granulosus tar DNA binding protein 0.0073 0.0298 0.0434
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0134
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0679 0.0996
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0016 0.0005 0.0001
Trichomonas vaginalis myo-inositol transporter, putative 0.0065 0.0259 0.1107
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0056 0.0223
Brugia malayi follicle stimulating hormone receptor 0.077 0.3867 1
Brugia malayi Pre-SET motif family protein 0.0225 0.1078 0.2779
Trypanosoma brucei glucose transporter, putative 0.0144 0.0661 0.8747
Echinococcus granulosus glycyl tRNA synthetase 0.0026 0.0058 0.008
Loa Loa (eye worm) CXXC zinc finger family protein 0.0094 0.0406 0.1041
Brugia malayi glycyl-tRNA synthetase 0.0026 0.0058 0.014
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0142 0.0652 0.0956
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0175 0.0742
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Loa Loa (eye worm) CHromoDomain protein family member 0.0018 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0057 0.0215 0.0546
Plasmodium falciparum calcium-dependent protein kinase 3 0.0142 0.0652 0.0648
Loa Loa (eye worm) follicle stimulating hormone receptor 0.077 0.3867 1
Onchocerca volvulus 0.0053 0.0197 0.1563
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0298 0.0439
Toxoplasma gondii sugar transporter ST1 0.0065 0.0259 0.0383
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0147 0.0679 0.1748
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0078 0.0319
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0056 0.0095
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1237 0.5369
Plasmodium vivax sugar transporter, putative 0.0065 0.0259 0.0254
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0892 0.4494 0.6623
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0056 0.0134
Schistosoma mansoni opsin-like receptor 0.0015 0.0004 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0004 0.0006
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0298 0.076
Schistosoma mansoni survival motor neuron protein 0.0053 0.0197 0.029
Schistosoma mansoni histidyl-tRNA synthetase 0.0016 0.0005 0.0008
Onchocerca volvulus 0.0094 0.0406 0.3267
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0124 0.2654
Treponema pallidum threonyl-tRNA synthetase 0.0026 0.0058 0.3127
Plasmodium vivax hexose transporter 0.0463 0.2299 0.2295
Brugia malayi major facilitator superfamily protein 0.0065 0.0259 0.0659
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0088
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0132 0.0602 0.0883
Loa Loa (eye worm) beta-lactamase 0.0039 0.0124 0.0311
Echinococcus multilocularis peregrin 0.0035 0.0106 0.015
Onchocerca volvulus 0.0065 0.0259 0.2067
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0124 0.1592
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0225 0.1078 0.2779
Echinococcus multilocularis synaptic vesicle 2 protein 0.0065 0.0259 0.0376
Echinococcus multilocularis General substrate transporter 0.0398 0.1965 0.2893
Echinococcus multilocularis geminin 0.1069 0.5401 0.7961
Echinococcus granulosus neuropeptide receptor A26 0.047 0.2333 0.3435
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Brugia malayi chromobox protein homolog 3 0.0042 0.0141 0.0354
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0124 0.2654
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0103 0.0455 1
Echinococcus multilocularis tumor protein p63 0.0387 0.1907 0.2808
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0175 0.0257
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0085 0.0119
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0124 0.1368
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0016 0.0005 0.0001
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0154 0.0149
Brugia malayi Bromodomain containing protein 0.0035 0.0106 0.0263
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0056 0.0685
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0099 0.0146
Brugia malayi Major Facilitator Superfamily protein 0.0065 0.0259 0.0659
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0026 0.0058 0.0346
Schistosoma mansoni cpg binding protein 0.0099 0.0434 0.064
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0142 0.0652 0.8623
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0142 0.0652 0.0648
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0124 0.0183
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0158 0.1245
Echinococcus granulosus lysyl tRNA synthetase 0.0103 0.0455 0.0665
Schistosoma mansoni amine GPCR 0.0015 0.0004 0.0006
Onchocerca volvulus 0.0065 0.0259 0.2067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0679 0.1002
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0004 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0004 0.0006
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0056 0.0223
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0056 0.1142
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0026 0.0058 0.014
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0016 0.0005 0.0008
Brugia malayi acetyltransferase, GNAT family protein 0.0166 0.0775 0.1996
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0088 0.0375 0.3026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0097 0.0403
Schistosoma mansoni histidyl-tRNA synthetase 0.0016 0.0005 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0097 0.0403
Schistosoma mansoni aspartyl-tRNA synthetase 0.0016 0.0005 0.0007
Trypanosoma cruzi hexose transporter, putative 0.0144 0.0661 0.8747
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0142 0.0652 0.0956
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0065 0.0259 0.0254
Giardia lamblia Threonyl-tRNA synthetase 0.0026 0.0058 0.01
Chlamydia trachomatis proline--tRNA ligase 0.0049 0.0176 0.3815
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0043 0.0166
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0679 0.0996
Trypanosoma brucei glucose transporter, putative 0.0144 0.0661 0.8747
Schistosoma mansoni protein kinase 0.0142 0.0652 0.0961
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0141 0.0594
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0026 0.0058 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0259 0.1107
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0141 0.1112
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0215 0.0317
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0004 0.0006
Leishmania major glucose transporter/membrane transporter D2, putative 0.0144 0.0661 0.8747
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0142 0.0652 0.0956
Onchocerca volvulus 0.0065 0.0259 0.2067
Schistosoma mansoni hypothetical protein 0.0102 0.0447 0.0659
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0124 0.1592
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0162 0.0239
Leishmania major threonyl-tRNA synthetase, putative 0.0026 0.0058 0.0715
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0035 0.0402
Onchocerca volvulus 0.0033 0.0094 0.0732
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0023 0.0043 0.0058
Schistosoma mansoni neuropeptide receptor 0.0015 0.0004 0.0006
Loa Loa (eye worm) RNA binding protein 0.0073 0.0298 0.076
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0107 0.0152
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0298 0.0439
Trypanosoma brucei glucose transporter, putative 0.0144 0.0661 0.8747
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0142 0.0652 0.0956
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0142 0.0652 0.1676
Loa Loa (eye worm) hypothetical protein 0.0039 0.0124 0.0311
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0004 0.0006
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0449 0.0656
Onchocerca volvulus 0.0065 0.0259 0.2067
Trypanosoma brucei glucose transporter, putative 0.0144 0.0661 0.8747
Brugia malayi hypothetical protein 0.026 0.1257 0.3244
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0004 0.0006
Schistosoma mansoni lipoxygenase 0.0132 0.0602 0.0888
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0056 0.1142
Echinococcus granulosus tumor protein p63 0.0387 0.1907 0.2808
Onchocerca volvulus 0.0057 0.0215 0.1712
Onchocerca volvulus 0.0039 0.0124 0.0974
Toxoplasma gondii glycyl-tRNA synthetase 0.0026 0.0058 0.0081
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0107 0.0152
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0016 0.0005 0.0001
Loa Loa (eye worm) sugar transporter 0.0065 0.0259 0.0659
Trypanosoma brucei glucose transporter, putative 0.0144 0.0661 0.8747
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0103 0.0455 0.1962
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0026 0.0058 0.0081
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0103 0.0455 0.5997
Onchocerca volvulus 0.0256 0.1235 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0004 0.0006
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0038 0.0033
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0259 0.3384
Loa Loa (eye worm) hypothetical protein 0.0102 0.0447 0.1146
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0259 0.1107
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0056 0.1142
Entamoeba histolytica hypothetical protein 0.0036 0.0107 0.019
Leishmania major protein kinase, putative 0.0142 0.0652 0.8623
Loa Loa (eye worm) 63kd antigen 0.0016 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0094 0.0233
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0107 0.0158
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0463 0.2299 0.3385
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Trypanosoma brucei glucose transporter 1E 0.0144 0.0661 0.8747
Schistosoma mansoni sugar transporter 0.0065 0.0259 0.0381
Schistosoma mansoni opsin-like receptor 0.0015 0.0004 0.0006
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0065 0.0259 0.5643
Schistosoma mansoni histamine h1 receptor 0.0015 0.0004 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.008 0.0112
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0004 0.0006
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0023 0.0043 0.0508
Brugia malayi Major Facilitator Superfamily protein 0.0065 0.0259 0.0659
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0162 0.0755 1
Schistosoma mansoni biogenic amine receptor 0.0015 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0031 0.0085 0.0125
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0102 0.0447 0.1146
Loa Loa (eye worm) acetyltransferase 0.0166 0.0775 0.1996
Schistosoma mansoni hypothetical protein 0.0463 0.2299 0.3389
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0026 0.0058 0.014
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0023 0.0043 0.0508
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0124 0.0903
Schistosoma mansoni loxhd1 0.0022 0.0038 0.0056
Mycobacterium ulcerans hypothetical protein 0.0039 0.0124 0.2654
Schistosoma mansoni rab6-interacting 0.0022 0.0038 0.0056
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0102 0.0447 0.0654
Onchocerca volvulus 0.0022 0.0038 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Trichomonas vaginalis CAMK family protein kinase 0.0142 0.0652 0.2821
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0749 0.3761 0.3758
Schistosoma mansoni hypothetical protein 0.0019 0.0024 0.0036
Echinococcus granulosus dnaJ subfamily B 0.1339 0.6783 1
Giardia lamblia Lysyl-tRNA synthetase 0.0103 0.0455 0.0835
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0124 0.0521
Leishmania major histidyl-tRNA synthetase, putative 0.0016 0.0005 0.0005
Echinococcus granulosus chromobox protein 1 0.0075 0.0311 0.0452
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0124 0.0177
Echinococcus granulosus Threonyl tRNA synthetase C 0.0026 0.0058 0.008
Schistosoma mansoni glucose transport protein 0.0463 0.2299 0.3389
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0085 0.0209
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0016 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0036 0.0107 0.019
Schistosoma mansoni ap endonuclease 0.0021 0.0035 0.0051
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0026 0.0058 0.01
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0038 0.005
Echinococcus granulosus Sugar transporter ERD6 protein 0.0065 0.0259 0.0376
Loa Loa (eye worm) hypothetical protein 0.0139 0.0637 0.1638
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0016 0.0005 0.0001
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0023 0.0404
Loa Loa (eye worm) major facilitator superfamily transporter 0.0065 0.0259 0.0659
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0004 0.0006
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0099 0.0141
Schistosoma mansoni threonyl-tRNA synthetase 0.0016 0.0005 0.0008
Brugia malayi Doublecortin family protein 0.0022 0.0038 0.0088
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0035 0.003
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0016 0.0005 0.0014
Loa Loa (eye worm) histone methyltransferase 0.003 0.008 0.0196
Onchocerca volvulus 0.0065 0.0259 0.2067
Echinococcus granulosus GPCR family 2 0.0102 0.0447 0.0654
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0065 0.0259 0.2042
Schistosoma mansoni myosin xvIII 0.0015 0.0004 0.0006
Echinococcus multilocularis neuropeptide s receptor 0.047 0.2333 0.3435
Entamoeba histolytica protein kinase, putative 0.0142 0.0652 0.1201
Trypanosoma brucei THT1 - hexose transporter, putative 0.0144 0.0661 0.8747
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0148 0.0212
Brugia malayi hypothetical protein 0.0022 0.0038 0.0088
Treponema pallidum glycyl-tRNA synthetase 0.0016 0.0005 0.002
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0026 0.0058 0.0234
Brugia malayi hypothetical protein 0.0022 0.0038 0.0088
Brugia malayi Cam kinase protein 1 0.0142 0.0652 0.1676
Mycobacterium ulcerans beta-lactamase 0.0039 0.0124 0.2654
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0056 0.0095
Echinococcus multilocularis calcium dependent protein kinase 0.0133 0.0607 0.0889
Onchocerca volvulus 0.0026 0.0056 0.0422
Schistosoma mansoni glucose transport protein 0.0463 0.2299 0.3389
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0142 0.0652 0.0956
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0097 0.0403
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0259 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Toxoplasma gondii exonuclease III APE 0.0021 0.0035 0.0045
Schistosoma mansoni amine GPCR 0.0015 0.0004 0.0006
Schistosoma mansoni neuropeptide receptor 0.0015 0.0004 0.0006
Toxoplasma gondii histone lysine methyltransferase SET1 0.0183 0.0864 0.1297
Trichomonas vaginalis conserved hypothetical protein 0.0463 0.2299 1
Trypanosoma brucei glucose transporter, putative 0.0144 0.0661 0.8747
Schistosoma mansoni lysyl-tRNA synthetase 0.0103 0.0455 0.067
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0035 0.0131
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0124 0.0903
Trichomonas vaginalis sugar transport protein, putative 0.0065 0.0259 0.1107
Brugia malayi hypothetical protein 0.0065 0.0259 0.0659
Echinococcus multilocularis RUN 0.0022 0.0038 0.005
Echinococcus multilocularis survival motor neuron protein 1 0.026 0.1257 0.1849
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0004 0.0006
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0035 0.0056
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0065 0.0259 0.0376
Brugia malayi PHD-finger family protein 0.0016 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0026 0.0058 0.01
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1237 0.5369
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0085 0.0121
Schistosoma mansoni neuropeptide receptor 0.0015 0.0004 0.0006
Trypanosoma cruzi hexose transporter, putative 0.0144 0.0661 0.8747
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0146 0.0367
Brugia malayi beta-lactamase family protein 0.0039 0.0124 0.0311
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0103 0.0455 0.6932
Loa Loa (eye worm) hypothetical protein 0.0026 0.0058 0.014
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0154 0.0277
Echinococcus multilocularis solute carrier family 22 0.0065 0.0259 0.0376
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0255 0.065
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0162 0.0755 1
Trichomonas vaginalis helicase, putative 0.0021 0.0034 0.0127
Trypanosoma brucei THT1 - hexose transporter, putative 0.0144 0.0661 0.8747
Plasmodium vivax proline--tRNA ligase, putative 0.0162 0.0755 0.0751
Trypanosoma cruzi hexose transporter, putative 0.0144 0.0661 0.8747
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0035 0.003
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0049 0.0176 0.3815
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0026 0.0058 0.0715
Schistosoma mansoni polycystin 1-related 0.0022 0.0038 0.0056
Loa Loa (eye worm) hypothetical protein 0.0034 0.0099 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0034 0.0127
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0051 0.0069
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0142 0.0652 0.1676
Schistosoma mansoni glucose transport protein 0.0463 0.2299 0.3389
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0311 0.1333
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0166 0.0775 0.1138
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0124 0.0119
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0006
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0103 0.0455 0.5997
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0162 0.0755 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0056 0.0326
Toxoplasma gondii facilitative glucose transporter GT1 0.0463 0.2299 0.3462
Mycobacterium ulcerans sugar transporter 0.0065 0.0259 0.5643
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0085 0.008
Schistosoma mansoni cpg binding protein 0.0099 0.0434 0.064
Toxoplasma gondii protein kinase, putative 0.1309 0.6632 1
Schistosoma mansoni aspartyl-tRNA synthetase 0.0016 0.0005 0.0007
Brugia malayi beta-lactamase family protein 0.0039 0.0124 0.0311
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0065 0.0259 0.0381
Schistosoma mansoni sugar transporter 0.0065 0.0259 0.0381
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0004 0.0006
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0175 0.0257
Chlamydia trachomatis lysine--tRNA ligase 0.0103 0.0455 1
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0043 0.0508
Plasmodium falciparum calcium-dependent protein kinase 2 0.0142 0.0652 0.0648
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0016 0.0005 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0078 0.0319
Onchocerca volvulus 0.0065 0.0259 0.2067
Onchocerca volvulus 0.0065 0.0259 0.2067
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0004 0.0006
Schistosoma mansoni protein kinase 0.0142 0.0652 0.0961
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0056 0.1142
Brugia malayi Heterochromatin protein 1 0.0075 0.0311 0.0793
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0175 0.017
Brugia malayi hypothetical protein 0.0065 0.0259 0.0659
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1237 0.5369
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0162 0.0755 1
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0023 0.0043 0.0508
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0004 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0785 0.3403
Mycobacterium tuberculosis Conserved protein 0.0039 0.0124 0.0903
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0035 0.0402
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0065 0.0259 0.2042
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1237 0.5369
Chlamydia trachomatis histidine--tRNA ligase 0.0016 0.0005 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0034 0.0127
Echinococcus multilocularis chromobox protein 1 0.0075 0.0311 0.0452
Brugia malayi hypothetical protein 0.0036 0.0107 0.0266
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0463 0.2299 0.3385
Schistosoma mansoni hypothetical protein 0.0102 0.0447 0.0659
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0102 0.0447 0.0654
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0035 0.1187
Loa Loa (eye worm) hypothetical protein 0.0039 0.0124 0.0311
Schistosoma mansoni sugar transporter 0.0065 0.0259 0.0381
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0026 0.0058 0.1193
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0026 0.0058 0.2114
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0004 0.0006
Leishmania major glucose transporter, lmgt2 0.0144 0.0661 0.8747
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0124 0.0311
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1067 0.5391 1
Brugia malayi major facilitator superfamily protein 0.0065 0.0259 0.0659
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0049
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0035 0.0079
Schistosoma mansoni aspartyl-tRNA synthetase 0.0016 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0102 0.0447 0.0659
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0023 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0056 0.0134
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0679 0.1002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0035 0.0046
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0016 0.0005 0.0002
Toxoplasma gondii sugar transporter ST2 0.0065 0.0259 0.0383
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0679 0.1002
Schistosoma mansoni rab6-interacting 0.0022 0.0038 0.0056
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0124 0.0521
Onchocerca volvulus 0.0065 0.0259 0.2067
Trichomonas vaginalis set domain proteins, putative 0.0256 0.1235 0.5365
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0463 0.2299 0.3385
Trichomonas vaginalis sugar transporter, putative 0.0144 0.0661 0.2861
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0124 0.0903
Plasmodium falciparum threonine--tRNA ligase 0.0026 0.0058 0.0054
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0341 0.0503
Plasmodium vivax calcium-dependent protein kinase, putative 0.0142 0.0652 0.0648
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0124 0.0521
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Loa Loa (eye worm) sugar transporter 0.0463 0.2299 0.594
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Echinococcus multilocularis glycyl tRNA synthetase 0.0026 0.0058 0.008
Plasmodium falciparum proline--tRNA ligase 0.0162 0.0755 0.0751
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Loa Loa (eye worm) hypothetical protein 0.022 0.1053 0.2715
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0463 0.2299 0.3385
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0304 0.148 0.2739
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0142 0.0652 0.1676
Trichomonas vaginalis glucose transporter, putative 0.0144 0.0661 0.2861
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0659
Echinococcus multilocularis solute carrier family 22 0.0065 0.0259 0.0376
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0026 0.0058 0.0715
Echinococcus multilocularis solute carrier family 22 0.0065 0.0259 0.0376
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0043 0.0166
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0146 0.0215
Echinococcus multilocularis chromobox protein 1 0.0075 0.0311 0.0452
Echinococcus granulosus solute carrier family 22 0.0065 0.0259 0.0376
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0049
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.0611 0.157
Schistosoma mansoni biogenic amine receptor 0.0015 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0034 0.0127
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0004 0.0006
Schistosoma mansoni chromobox protein 0.0075 0.0311 0.0458
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0023 0.0404
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0038 0.005
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0016 0.0005 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0097 0.0403
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Echinococcus granulosus peregrin 0.0035 0.0106 0.015
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0035 0.0402
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0035 0.0147
Schistosoma mansoni hypothetical protein 0.1069 0.5401 0.7962
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0322 0.1575 0.4067
Giardia lamblia Glycyl-tRNA synthetase 0.0026 0.0058 0.01
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0158 0.0666
Trichomonas vaginalis esterase, putative 0.0039 0.0124 0.0521
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0832 0.3605
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0016 0.0005 0.0002
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0142 0.0652 0.0956
Echinococcus granulosus chromobox protein 1 0.0075 0.0311 0.0452
Loa Loa (eye worm) latrophilin receptor protein 2 0.0102 0.0447 0.1146
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0085 0.0121
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0785 0.3403
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0099 0.0141
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.0103 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.0661 0.2861
Brugia malayi lysyl-tRNA synthetase 0.0103 0.0455 0.1166
Brugia malayi latrophilin 2 splice variant baaae 0.022 0.1053 0.2715
Schistosoma mansoni lipoxygenase 0.0092 0.0399 0.0588
Plasmodium vivax SET domain protein, putative 0.0034 0.0099 0.0095
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0148 0.0212
Loa Loa (eye worm) hypothetical protein 0.0039 0.0124 0.0311
Schistosoma mansoni aspartyl-tRNA synthetase 0.0016 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0134
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0142 0.0652 0.1676
Schistosoma mansoni biogenic amine receptor 0.0015 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0141 0.0354
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0016 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0124 0.0311
Trichomonas vaginalis sugar transporter, putative 0.0144 0.0661 0.2861
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1237 0.5369
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0035 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0043 0.0508
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0035 0.0079
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0142 0.0652 0.0977
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0026 0.0058 0.014
Entamoeba histolytica hypothetical protein 0.0036 0.0107 0.019
Plasmodium falciparum hexose transporter 0.0463 0.2299 0.2295
Loa Loa (eye worm) hypothetical protein 0.0103 0.0455 0.1166
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0298 0.0439
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0004 0.0006
Echinococcus granulosus histidyl tRNA synthetase 0.0016 0.0005 0.0002
Echinococcus granulosus solute carrier family 22 0.0065 0.0259 0.0376
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1237 0.5369
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0124 0.0177
Loa Loa (eye worm) hypothetical protein 0.0322 0.1575 0.4067
Echinococcus multilocularis dnaJ subfamily B 0.1339 0.6783 1
Brugia malayi Aspartyl-tRNA synthetase 0.0016 0.0005 0.0001
Echinococcus granulosus geminin 0.1069 0.5401 0.7961
Brugia malayi Calcitonin receptor-like protein seb-1 0.0322 0.1575 0.4067
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0259 0.1107
Plasmodium vivax lysine--tRNA ligase, putative 0.0103 0.0455 0.045
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0004 0.0006
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0139 0.0637 0.0939
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0298 0.0439
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0142 0.0652 0.0648
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0298 0.076
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0249 0.1198 1
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0679 0.0996
Toxoplasma gondii lysine-tRNA ligase 0.0103 0.0455 0.0679
Brugia malayi Pre-SET motif family protein 0.0034 0.0099 0.0246
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0051 0.0069
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0102 0.0447 0.0654
Brugia malayi PHD-finger family protein 0.0031 0.0085 0.0209
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0119 0.0169
Echinococcus multilocularis lysyl tRNA synthetase 0.0103 0.0455 0.0665
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0099 0.0146
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0004 0.0006
Onchocerca volvulus 0.0065 0.0259 0.2067
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0197 0.0498
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0749 0.3761 0.5668
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0124 0.0311
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0785 0.3403
Leishmania major glycyl tRNA synthetase, putative 0.0016 0.0005 0.0005
Plasmodium vivax glycine--tRNA ligase, putative 0.0026 0.0058 0.0054
Plasmodium falciparum calcium-dependent protein kinase 1 0.0142 0.0652 0.0648
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0175 0.0742
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0099 0.0146
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0038 0.005
Loa Loa (eye worm) major facilitator superfamily transporter 0.0065 0.0259 0.0659
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0004 0.0006
Toxoplasma gondii ABC1 family protein 0.0039 0.0124 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.0661 0.2861
Schistosoma mansoni amine GPCR 0.0015 0.0004 0.0006
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.0611 0.157
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0083 0.0116
Leishmania major myo-inositol/proton symporter (MIT) 0.0065 0.0259 0.3384
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0056 0.1142
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0051 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0034 0.0127
Schistosoma mansoni adenoreceptor 0.0015 0.0004 0.0006
Trypanosoma cruzi histidyl-tRNA synthetase 0.0016 0.0005 0.0005
Echinococcus granulosus cpg binding protein 0.0099 0.0434 0.0634
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0016 0.0005 0.0005
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0298 0.076
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0141 0.0594
Onchocerca volvulus 0.0065 0.0259 0.2067
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0038 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0043 0.0166
Onchocerca volvulus Putative transporter 0.0065 0.0259 0.2067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0097 0.0403
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0034 0.0127
Echinococcus granulosus synaptic vesicle 2 protein 0.0065 0.0259 0.0376
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.1237 0.319
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0124 0.0903
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0139 0.0637 0.1638
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0088 0.0375 0.3026
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0018 0.0015 0.0017
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.026 0.1257 0.3244
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0298 0.0434
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0016 0.0005 0.0001
Giardia lamblia Sugar-proton symporter 0.0065 0.0259 0.0471
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0124 0.0903
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0139 0.0637 0.0934
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0035 0.1755
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0056 0.1142
Giardia lamblia PHD finger protein 15 0.0031 0.0085 0.0149
Schistosoma mansoni cpg binding protein 0.0094 0.0406 0.0599
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0785 0.3403
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0142 0.0652 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Entamoeba histolytica protein kinase, putative 0.0142 0.0652 0.1201
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0298 0.0439
Mycobacterium ulcerans lipase LipD 0.0039 0.0124 0.2654
Schistosoma mansoni amine GPCR 0.0015 0.0004 0.0006
Echinococcus granulosus survival motor neuron protein 1 0.026 0.1257 0.1849
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0035 0.0046
Brugia malayi Sugar transporter family protein 0.0065 0.0259 0.0659
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0463 0.2299 0.3385
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0311 0.1333
Echinococcus granulosus General substrate transporter 0.0398 0.1965 0.2893
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0103 0.0455 1
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0259 0.1107
Brugia malayi RNA binding protein 0.0073 0.0298 0.076
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0201 0.0952 0.1404
Trypanosoma brucei glucose transporter 2A 0.0144 0.0661 0.8747
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0004 0.0006
Schistosoma mansoni opsin-like receptor 0.0015 0.0004 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0007 0.0002
Trypanosoma brucei glucose transporter, putative 0.0144 0.0661 0.8747
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0259 0.1107
Trypanosoma cruzi hexose transporter 0.0144 0.0661 0.8747
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0099 0.0141
Onchocerca volvulus 0.0065 0.0259 0.2067
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0124 0.0311
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0463 0.2299 0.3385
Chlamydia trachomatis threonine--tRNA ligase 0.0026 0.0058 0.1193

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 19.6 % Inhibition of thrombin at 20 uM preincubated for 15 mins before Boc-Val-Pro-Arg-AMC substrate addition measured after 10 mins by microtiter fluorescence plate reader analysis ChEMBL. 21641807
Inhibition (binding) = 20 % Inhibition of West Nile virus NS2B-NS3 serine protease at 50 uM preincubated for 15 mins before substrate addition measured after 15 mins by fluorimetric analysis ChEMBL. 21641807

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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