Detailed information for compound 993577

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 381.219 | Formula: C20H13BrO3
  • H donors: 1 H acceptors: 2 LogP: 4.62 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC1OC(=O)C(=C1c1cccc(c1)c1ccc2c(c1)cccc2)Br
  • InChi: 1S/C20H13BrO3/c21-18-17(19(22)24-20(18)23)16-7-3-6-14(11-16)15-9-8-12-4-1-2-5-13(12)10-15/h1-11,19,22H
  • InChiKey: MIGBIBPFXLKKON-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0009 0.002
Brugia malayi Bromodomain containing protein 0.0074 0.0358 0.0358
Brugia malayi jmjC domain containing protein 0.0094 0.0486 0.0486
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0047 0.0214
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0201 0.0201
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0302 0.1378
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0076 0.2062
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0043 0.0261
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0075 0.0368 0.5768
Echinococcus multilocularis FTZ F1 alpha 0.0638 0.3953 0.5532
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0007 0.0109
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0022 0.0032 0.0867
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0032 0.0183
Brugia malayi steroid hormone receptor 0.0638 0.3953 0.3953
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0015 0.0015
Schistosoma mansoni rab6-interacting 0.0058 0.0259 0.0363
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0009 0.0013
Brugia malayi nuclear hormone receptor family member odr-7 0.0301 0.1806 0.1806
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0451 0.0987
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.012 0.0263
Echinococcus granulosus tumor protein p63 0.0332 0.2001 0.438
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0639 1
Echinococcus granulosus RUN 0.0058 0.0259 0.0567
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0032 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0208 0.1474
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0073 0.1826
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0301 0.1806 0.4548
Loa Loa (eye worm) hypothetical protein 0.0638 0.3953 0.4891
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0073 0.0484
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0073 0.0484
Brugia malayi 6-phosphofructokinase 0.0107 0.0569 0.0569
Brugia malayi Cytochrome P450 family protein 0.0055 0.0239 0.0239
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0638 0.3953 0.5532
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0451 0.0631
Echinococcus multilocularis neuropeptide receptor A26 0.0463 0.2839 0.3973
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0032 0.0045
Loa Loa (eye worm) hypothetical protein 0.016 0.091 0.1125
Trypanosoma brucei C-8 sterol isomerase, putative 0.0361 0.2191 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.017 0.0238
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0032 0.0183
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0011
Echinococcus multilocularis geminin 0.0166 0.0949 0.1327
Plasmodium vivax heterochromatin protein 1, putative 0.0022 0.0032 0.0691
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0009 0.0011
Echinococcus granulosus nuclear receptor nhr 48 0.0301 0.1806 0.3953
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0638 0.3953 0.3953
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0638 0.3953 0.8651
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.004
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0208 0.0291
Echinococcus multilocularis dna polymerase eta 0.0019 0.001 0.0014
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0009 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0057 0.0369
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0301 0.1806 0.3953
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0486 0.068
Onchocerca volvulus 0.0026 0.0058 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0638 0.3953 0.3953
Brugia malayi Nuclear hormone receptor-like 1 0.1286 0.8083 0.8083
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.001 0.0046
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0259 0.0363
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0223 0.1587
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.0777
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0114 0.016
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0205 0.1451
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0638 0.3953 0.5532
Echinococcus multilocularis Protein lozenge 0.0055 0.0237 0.0331
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0208 0.0291
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0128 0.0179
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0208 0.1474
Loa Loa (eye worm) glutathione reductase 0.0046 0.0185 0.0229
Brugia malayi Protein cec-1. 0.0022 0.0032 0.0032
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0013
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0113 0.0516
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0009 0.0013
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0043 0.0093
Loa Loa (eye worm) hypothetical protein 0.0435 0.2658 0.3288
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0638 0.3953 0.3953
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.017 0.0777
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0043 0.0666
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0208 0.0949
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0569 0.0796
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.017 0.1198
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0208 1
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0009 0.0013
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0055 0.0068
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.001 0.001
Plasmodium vivax SET domain protein, putative 0.0029 0.0076 0.191
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0638 0.3953 0.8651
Schistosoma mansoni bromodomain containing protein 0.0062 0.0285 0.0399
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0302 0.1378
Loa Loa (eye worm) hypothetical protein 0.0435 0.2658 0.3288
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0569 0.4122
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0073 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0121 0.0833
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0055 0.025
Schistosoma mansoni polycystin 1-related 0.0058 0.0259 0.0363
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.001 0.0046
Schistosoma mansoni hypothetical protein 0.0022 0.0032 0.0045
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.119 0.1473
Schistosoma mansoni hypothetical protein 0.0047 0.0191 0.0267
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0055 0.0068
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0638 0.3953 0.3953
Loa Loa (eye worm) hypothetical protein 0.0337 0.2036 0.2519
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0185 0.0844
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0638 0.3953 0.5532
Trypanosoma brucei unspecified product 0.0019 0.001 0.0046
Schistosoma mansoni thyroid hormone receptor 0.1139 0.7146 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0009 0.0013
Brugia malayi phosphofructokinase 0.0107 0.0569 0.0569
Schistosoma mansoni nuclear receptor 0.0301 0.1806 0.2528
Schistosoma mansoni chromobox protein 0.0022 0.0032 0.0045
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0073 0.1175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.0777
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0032 0.0183
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.017 0.0211
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0301 0.1806 0.2528
Loa Loa (eye worm) hypothetical protein 0.0026 0.0058 0.0072
Schistosoma mansoni hypothetical protein 0.0166 0.0949 0.1327
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0121 0.2022
Echinococcus granulosus Nuclear hormone receptor HR96 0.0301 0.1806 0.3953
Schistosoma mansoni DNA polymerase eta 0.0019 0.001 0.0014
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0121 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0183
Loa Loa (eye worm) hypothetical protein 0.004 0.0144 0.0178
Loa Loa (eye worm) hypothetical protein 0.0058 0.0259 0.0321
Onchocerca volvulus Bile acid receptor homolog 0.0638 0.3953 1
Brugia malayi hypothetical protein 0.0337 0.2036 0.2036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0638 0.3953 0.3953
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0018 0.0023
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0121 0.5653
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0009 0.0017
Leishmania major cytochrome p450-like protein 0.0026 0.0055 0.025
Brugia malayi SET domain containing protein 0.0023 0.0039 0.0039
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.001 0.001
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0073 0.1826
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.012 0.0549
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0009 0.0013
Brugia malayi hypothetical protein 0.0301 0.1806 0.1806
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0032 0.0445
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0096 0.1504
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0114 0.0114
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0009 0.002
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0043 0.0748
Echinococcus granulosus lamin 0.0026 0.0058 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0638 0.3953 0.3953
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.017 0.2907
Schistosoma mansoni lipoxygenase 0.0224 0.1317 0.1843
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0128 0.0281
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0047 0.0214
Brugia malayi M-phase phosphoprotein, mpp8 0.0111 0.0594 0.0594
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0357
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.017 0.2907
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0022 0.0102
Onchocerca volvulus 0.003 0.0081 0.0166
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0009 0.002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.001 0.0012
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0337 0.2036 0.4456
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0043 0.0748
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0122 0.0267
Brugia malayi CHD4 protein 0.0024 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0185 0.1066 0.1319
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0121 0.055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0041 0.0249
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0193 0.0271
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0302 0.0374
Onchocerca volvulus 0.0111 0.0594 0.1469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0098 0.067
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0638 0.3953 0.8651
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0009 0.0009
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0047 0.1274
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.1219 0.5564
Plasmodium vivax glutathione reductase, putative 0.0046 0.0185 0.4923
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0041 0.025
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.012 1
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0569 0.2596
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0012 0.0017
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0032 0.0183
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0451 0.0631
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0638 0.3953 0.4891
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0017
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0638 0.3953 0.5532
Mycobacterium ulcerans hypothetical protein 0.002 0.0015 0.0271
Echinococcus granulosus neuropeptide receptor A26 0.0463 0.2839 0.6214
Schistosoma mansoni rab6-interacting 0.0058 0.0259 0.0363
Brugia malayi Valyl-tRNA synthetase 0.0022 0.0032 0.0032
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.017 0.0777
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0009 0.0013
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.191
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.012 0.2017
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0301 0.1806 0.2528
Brugia malayi nuclear receptor NHR-67 0.0301 0.1806 0.1806
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0121 0.0833
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0301 0.1806 0.3953
Schistosoma mansoni hypothetical protein 0.002 0.0018 0.0026
Echinococcus granulosus intermediate filament protein 0.0026 0.0058 0.0127
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0263 0.0367
Schistosoma mansoni steroid hormone receptor ad4bp 0.0638 0.3953 0.5532
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0185 0.0259
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.003 0.0042
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0098 0.2668
Brugia malayi nuclear hormone receptor 0.0301 0.1806 0.1806
Loa Loa (eye worm) hypothetical protein 0.0033 0.0102 0.0127
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0075 0.0368 0.5768
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0301 0.1806 0.2528
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0208 0.0949
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0032 0.0867
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.0044 0.0096
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0185 0.2895
Brugia malayi intermediate filament protein 0.0026 0.0058 0.0058
Echinococcus granulosus Polycystic kidney disease protein 0.0058 0.0259 0.0567
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0043 0.0194
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0185 0.0405
Echinococcus granulosus expressed protein 0.0366 0.2223 0.4864
Loa Loa (eye worm) nuclear hormone receptor 0.0301 0.1806 0.2235
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0017
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0259 0.0363
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0191 0.0191
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0032 0.0183
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0009 0.0011
Mycobacterium tuberculosis Conserved protein 0.0024 0.0043 0.0666
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0183
Brugia malayi hypothetical protein 0.0435 0.2658 0.2658
Loa Loa (eye worm) hypothetical protein 0.0049 0.0201 0.0249
Loa Loa (eye worm) hypothetical protein 0.125 0.7853 0.9716
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0185 0.0229
Brugia malayi orphan nuclear receptor NR2E1 0.0301 0.1806 0.1806
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.003 0.0066
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.012 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0205 0.1451
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0047 0.1106
Echinococcus multilocularis thyroid hormone receptor alpha 0.1139 0.7146 1
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0022 0.0032 0.007
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0007 0.0032
Schistosoma mansoni hypothetical protein 0.0166 0.0949 0.1327
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0501 0.3082 0.4313
Leishmania major trypanothione reductase 0.0046 0.0185 0.0844
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0013
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0007 0.0009
Echinococcus multilocularis chromobox protein 2 0.0022 0.0032 0.0045
Brugia malayi Bromodomain containing protein 0.0038 0.0129 0.0129
Brugia malayi ecdysone receptor 0.0301 0.1806 0.1806
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0068
Leishmania major hypothetical protein, conserved 0.0025 0.0047 0.0214
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0007 0.0007
Brugia malayi Nuclear hormone receptor E75 0.0301 0.1806 0.1806
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0639 1
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0043 0.006
Schistosoma mansoni inositol monophosphatase 0.0036 0.012 0.0168
Onchocerca volvulus 0.0026 0.0058 0.0108
Onchocerca volvulus 0.0058 0.0259 0.0619
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0009 0.0013
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.001 0.0022
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0069 0.0151
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0205 0.0481
Brugia malayi Cytochrome P450 family protein 0.0026 0.0055 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0183
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.017 0.0238
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.003 0.0042
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0009 0.0013
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0032 0.0045
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0638 0.3953 0.4891
Brugia malayi hypothetical protein 0.0337 0.2036 0.2036
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0302 0.1378
Loa Loa (eye worm) hypothetical protein 0.0049 0.0199 0.0246
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0019
Mycobacterium ulcerans hypothetical protein 0.0024 0.0043 0.0748
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0208 0.0455
Brugia malayi Thioredoxin reductase 0.0046 0.0185 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0638 0.3953 0.3953
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0006 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.012 0.0549
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.017 0.0777
Schistosoma mansoni hypothetical protein 0.0501 0.3082 0.4313
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0032 0.0045
Onchocerca volvulus Alhambra homolog 0.0029 0.0072 0.0143
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0569 0.0796
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0639 1
Brugia malayi hypoxia-induced factor 1 0.0148 0.0831 0.0831
Onchocerca volvulus Protein ultraspiracle homolog 0.0638 0.3953 1
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0569 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0121 0.0149
Schistosoma mansoni chromobox protein 0.008 0.0396 0.0554
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0032 0.0183
Brugia malayi hypothetical protein 0.016 0.091 0.091
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0073 0.198
Giardia lamblia GTOR 0.0044 0.017 0.8129
Loa Loa (eye worm) hypothetical protein 0.0337 0.2036 0.2519
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0012 0.0017
Schistosoma mansoni retinoic acid receptor RXR 0.0735 0.4569 0.6394
Brugia malayi Pre-SET motif family protein 0.0029 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0098 0.067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0032 0.0183
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0564 0.8822
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.012 0.0549
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0121 0.0169
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Echinococcus multilocularis ecdysone induced protein 78C 0.0638 0.3953 0.5532
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0057 0.0369
Echinococcus granulosus Chromo domain 0.0022 0.0032 0.007
Plasmodium falciparum heterochromatin protein 1 0.0022 0.0032 0.0691
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0122 0.0171
Schistosoma mansoni ap endonuclease 0.0018 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0011
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0208 0.0291
Brugia malayi PHD-finger family protein 0.0029 0.0072 0.0072
Schistosoma mansoni lipoxygenase 0.012 0.0651 0.0911
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0075 0.0368 1
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0075 0.0368 0.0368
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.017 0.1198
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0096 0.1504
Mycobacterium ulcerans epimerase 0.002 0.0015 0.0271
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0638 0.3953 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0072 0.0089
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.191
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0041 0.025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0638 0.3953 0.3953
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0009 0.0013
Giardia lamblia DINP protein human, muc B family 0.0019 0.001 0.0153
Schistosoma mansoni hypothetical protein 0.0033 0.0102 0.0143
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0302 0.0302
Schistosoma mansoni chromobox protein 0.008 0.0396 0.0554
Loa Loa (eye worm) runx1 0.0055 0.0237 0.0293
Trypanosoma brucei protein kinase, putative 0.005 0.0208 0.0949
Schistosoma mansoni nuclear hormone receptor 0.0301 0.1806 0.2528
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0337 0.2036 0.285
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0569 0.4122
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0032 0.0867
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0569 0.0704
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0224 0.1317 0.1843
Brugia malayi hypothetical protein 0.0111 0.0594 0.0594
Mycobacterium tuberculosis Probable reductase 0.0106 0.0564 0.8822
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0041 0.025
Echinococcus granulosus geminin 0.0166 0.0949 0.2076
Trypanosoma brucei trypanothione reductase 0.0046 0.0185 0.0844
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.017 0.0777
Brugia malayi 6-phosphofructokinase 0.0107 0.0569 0.0569
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0569 0.0796
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0208 0.0949
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0183 0.04
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.001 0.0157
Schistosoma mansoni RAR-like nuclear receptor 0.0638 0.3953 0.5532
Trichomonas vaginalis hypothetical protein 0.0022 0.0032 0.0183
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0032 0.0183
Schistosoma mansoni single-minded 0.0048 0.0193 0.0271
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0199 0.0278
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.1368 0.2993
Brugia malayi conserved hypotetical protein 0.0301 0.1806 0.1806
Echinococcus granulosus chromobox protein 1 0.008 0.0396 0.0867
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0638 0.3953 0.5532
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.012 0.0831
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.001 0.0046
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0047 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.0777
Echinococcus multilocularis Chromo domain 0.0022 0.0032 0.0045
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0009 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0208 0.1474
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0122 0.0171
Echinococcus granulosus neuropeptide s receptor 0.0463 0.2839 0.6214
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0121 0.0264
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0301 0.1806 0.4548
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0098 0.067
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0009 0.0009
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0121 0.0169
Onchocerca volvulus 0.0435 0.2658 0.6711
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0012
Plasmodium vivax multidomain scavenger receptor, putative 0.0058 0.0259 0.6975
Brugia malayi hypothetical protein 0.0058 0.0259 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0009 0.0013
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0259 0.0567
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0011
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.001 0.0046
Echinococcus multilocularis tumor protein p63 0.0332 0.2001 0.2801
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0102 0.0102
Brugia malayi Nuclear hormone receptor E75 0.0301 0.1806 0.1806
Brugia malayi nuclear hormone receptor 0.0638 0.3953 0.3953
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0302 0.5251
Brugia malayi glutathione reductase 0.0046 0.0185 0.0185
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0073 0.198
Brugia malayi hypothetical protein 0.0035 0.0114 0.0114
Brugia malayi hypothetical protein 0.0025 0.0047 0.0047
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0208 0.0949
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0183
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0337 0.2036 0.285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0041 0.025
Toxoplasma gondii exonuclease III APE 0.0018 0.0007 0.0189
Trichomonas vaginalis chromobox protein, putative 0.008 0.0396 0.2855
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0098 0.067
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0638 0.3953 0.3953
Schistosoma mansoni thyroid hormone receptor 0.1139 0.7146 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0044 0.0061
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0058 0.0072
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0208 0.0949
Onchocerca volvulus 0.0301 0.1806 0.4548
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0121 0.055
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.001 0.0176
Brugia malayi nuclear receptor RXR 0.0301 0.1806 0.1806
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0259 0.0567
Echinococcus granulosus thyroid hormone receptor alpha 0.0301 0.1806 0.3953
Echinococcus multilocularis Polycystic kidney disease protein 0.0058 0.0259 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0638 0.3953 0.3953
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0017
Onchocerca volvulus 0.0052 0.0219 0.0516
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0208 0.1474
Echinococcus multilocularis lamin dm0 0.0026 0.0058 0.0081
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0361 0.2191 0.2191
Mycobacterium ulcerans endonuclease IV 0.0075 0.0368 0.6478
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0208 0.5642
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0032 0.0445
Brugia malayi nuclear hormone receptor family member nhr-6 0.0301 0.1806 0.1806
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0208 0.0455
Trichomonas vaginalis chromobox protein, putative 0.008 0.0396 0.2855
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0009 0.002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0564 0.8822
Schistosoma mansoni lozenge 0.0055 0.0237 0.0331
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0058 0.0058
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0032 0.0691
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0638 0.3953 0.4891
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0098 0.067
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0143 0.02
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0451 0.0631
Schistosoma mansoni nuclear hormone receptor 0.0301 0.1806 0.2528
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0058 0.0072
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0223 0.1587
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0569 0.4122
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.1219 0.5564
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.017 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.0777
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0638 0.3953 0.5532
Loa Loa (eye worm) hypothetical protein 0.0232 0.1368 0.1692
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.012 0.0831
Schistosoma mansoni zinc finger protein 0.0301 0.1806 0.2528
Giardia lamblia PHD finger protein 15 0.0029 0.0072 0.3219
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0078 0.052
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0114 0.025
Schistosoma mansoni hypothetical protein 0.0058 0.0259 0.0363
Echinococcus multilocularis zinc finger protein 0.0019 0.0012 0.0016
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0121 0.0264
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0302 0.0423
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.012 0.2114
Schistosoma mansoni inositol monophosphatase 0.0036 0.012 0.0168
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0638 0.3953 0.5532
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0569 0.2596
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0007 0.0032
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0569 0.8904
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0638 0.3953 0.3953
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Onchocerca volvulus 0.0047 0.0191 0.0446
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0301 0.1806 0.2528
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.035 0.0489
Echinococcus multilocularis dna polymerase kappa 0.0019 0.001 0.0014
Schistosoma mansoni lamin 0.0026 0.0058 0.0081
Echinococcus multilocularis expressed protein 0.0366 0.2223 0.311
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0208 0.0949
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Brugia malayi nuclear receptor RXR 0.0337 0.2036 0.2036
Loa Loa (eye worm) hypothetical protein 0.0111 0.0594 0.0735
Brugia malayi Cytochrome P450 family protein 0.0026 0.0055 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0638 0.3953 0.4891
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0361 0.2191 1
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0022 0.0032 0.0691
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Brugia malayi small heat shock protein 0.0567 0.35 0.35
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0569 0.0704
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0638 0.3953 0.8651
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.001 0.0023
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0055 0.025
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0009 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0638 0.3953 0.8651
Brugia malayi tailless protein 0.0301 0.1806 0.1806
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0055 0.025
Echinococcus granulosus Nuclear hormone receptor HR96 0.0301 0.1806 0.3953
Schistosoma mansoni nuclear receptor nhr-48 0.0301 0.1806 0.2528
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.1286 0.8083 1
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0032 0.0691
Loa Loa (eye worm) helicase 0.0022 0.0032 0.004
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0072 0.1944
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0638 0.3953 0.3953
Schistosoma mansoni hypothetical protein 0.0029 0.0072 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.017 0.1198
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0032 0.0691
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0073 0.0484
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0032 0.0183
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0009 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0183
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0076 0.0106
Brugia malayi MAP kinase sur-1 0.005 0.0208 0.0208
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0013
Brugia malayi hypothetical protein 0.0301 0.1806 0.1806
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Brugia malayi hypothetical protein 0.0232 0.1368 0.1368
Schistosoma mansoni intermediate filament proteins 0.0026 0.0058 0.0081
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0009 0.0013
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0113 0.0516
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0072 0.01
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.001 0.0157
Echinococcus multilocularis chromobox protein 1 0.008 0.0396 0.0554
Plasmodium falciparum glutathione reductase 0.0046 0.0185 0.4923
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0114 0.0249
Loa Loa (eye worm) hypothetical protein 0.0046 0.0183 0.0226
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0072 0.1789
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0057 0.0369
Loa Loa (eye worm) hypothetical protein 0.003 0.0081 0.01
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.017 0.0777
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0337 0.2036 0.285
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0052 0.0219 0.0306
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0007 0.0122
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0073 0.1826
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0121 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0009 0.002
Brugia malayi nuclear receptor NHR-88 0.0638 0.3953 0.3953
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0076 0.0106
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.004
Trypanosoma brucei hypothetical protein, conserved 0.0209 0.1219 0.5564
Loa Loa (eye worm) hypothetical protein 0.005 0.0205 0.0253
Entamoeba histolytica hypothetical protein 0.0022 0.0032 0.0445
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0007 0.001
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.001 0.0055
Loa Loa (eye worm) hypothetical protein 0.0638 0.3953 0.4891
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.001 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0073 0.0484
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0055 0.0963
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0072 0.01
Brugia malayi PAS domain containing protein 0.0048 0.0193 0.0193
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0015 0.0241
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.001 0.0046
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0638 0.3953 0.5532
Brugia malayi PXA domain containing protein 0.0019 0.0009 0.0009
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0022 0.0032 0.0045
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0041 0.0249
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0009 0.0013
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0007 0.0015
Plasmodium falciparum thioredoxin reductase 0.0046 0.0185 0.4923
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0015 0.0271
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0052 0.0223 0.0528
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0301 0.1806 0.2528
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0098 0.067
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0121 0.055
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0129 0.0897
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0072 0.1944
Toxoplasma gondii endonuclease IV APN 0.0075 0.0368 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.012 0.3264
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.001 0.0046
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0007 0.0032
Schistosoma mansoni chromobox protein 0.0022 0.0032 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0062 0.0406
Loa Loa (eye worm) hypothetical protein 0.0638 0.3953 0.4891
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0011
Entamoeba histolytica hypothetical protein 0.0022 0.0032 0.0445
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0735 0.4569 1
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.1368 0.1914
Loa Loa (eye worm) hypothetical protein 0.0337 0.2036 0.2519
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.0044 0.0061
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0183 0.0256
Onchocerca volvulus 0.0301 0.1806 0.4548
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.004
Echinococcus granulosus lamin dm0 0.0026 0.0058 0.0127
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0263 0.0575
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0398 0.2423 0.339
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0569 0.4122
Onchocerca volvulus 0.0111 0.0594 0.1469
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0043 0.0194
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0239 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0357
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.001 0.0046
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0032 0.0445
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0069 0.0331 0.041
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0007 0.0032
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.191
Loa Loa (eye worm) hypothetical protein 0.0337 0.2036 0.2519
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0009 0.0009
Loa Loa (eye worm) doublecortin family protein 0.0058 0.0259 0.0321
Echinococcus multilocularis lamin 0.0026 0.0058 0.0081
Leishmania major C-8 sterol isomerase-like protein 0.0361 0.2191 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.001 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0638 0.3953 0.3953
Brugia malayi PHD-finger family protein 0.0024 0.0045 0.0045
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0796 0.4958 0.6939
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0073 0.198
Brugia malayi Bromodomain containing protein 0.0031 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Loa Loa (eye worm) nuclear receptor NHR-67 0.0301 0.1806 0.2235
Loa Loa (eye worm) hypothetical protein 0.0638 0.3953 0.4891
Trichomonas vaginalis Heterochromatin protein, putative 0.0022 0.0032 0.0183
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0638 0.3953 0.5532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0041 0.0249
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0564 0.8822
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0113 0.0777
Brugia malayi Heterochromatin protein 1 0.008 0.0396 0.0396
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0012 0.0015
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.0044 0.0054
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0073 0.0484
Echinococcus granulosus dna polymerase kappa 0.0019 0.001 0.0022
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0301 0.1806 0.1806
Echinococcus multilocularis Chromobox protein 3 0.0022 0.0032 0.0045
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0638 0.3953 0.5532
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0501 0.3082 0.6745
Schistosoma mansoni hypothetical protein 0.0035 0.0114 0.016
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0012 0.0017
Echinococcus granulosus ecdysone induced protein 78C 0.0638 0.3953 0.8651
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0032 0.0183
Onchocerca volvulus 0.0233 0.1371 0.3442
Schistosoma mansoni survival motor neuron protein 0.0047 0.0191 0.0267
Schistosoma mansoni nuclear receptor 0.0301 0.1806 0.2528
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.001 0.0014
Trichomonas vaginalis set domain proteins, putative 0.0232 0.137 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0047 0.1106
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.001 0.0046
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0009 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0183 0.0256
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Loa Loa (eye worm) steroid hormone receptor 0.0638 0.3953 0.4891
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0201 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0017
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0302 0.1378
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0043 0.0194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0638 0.3953 0.4891
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0122 0.0151
Loa Loa (eye worm) hypothetical protein 0.0049 0.0202 0.025
Onchocerca volvulus 0.0058 0.0259 0.0619
Schistosoma mansoni zinc finger protein 0.0019 0.0012 0.0016
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0564 0.8822
Brugia malayi Nuclear hormone receptor-like 1 0.1286 0.8083 0.8083
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0183
Leishmania major hypothetical protein, conserved 0.0209 0.1219 0.5564
Brugia malayi Doublecortin family protein 0.0058 0.0259 0.0259
Brugia malayi Inositol-1 0.0036 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.011 0.0154
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0201 0.0249
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0121 0.0264
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0032 0.0183
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0055 0.0068
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0638 0.3953 0.5532
Echinococcus granulosus dna polymerase eta 0.0019 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0011
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0364 0.0509
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0075 0.0368 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0486 0.1064
Plasmodium falciparum phd finger protein, putative 0.0029 0.0072 0.1789
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0569 1
Brugia malayi hypothetical protein 0.0058 0.0259 0.0259
Echinococcus granulosus chromobox protein 1 0.008 0.0396 0.0867
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0569 1
Echinococcus granulosus Chromobox protein 3 0.0022 0.0032 0.007
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0638 0.3953 0.8651
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0062 0.0406
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0224 0.1317 0.2882
Chlamydia trachomatis endonuclease IV 0.0075 0.0368 1
Brugia malayi Associated with TFs and helicases family protein 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0058
Echinococcus multilocularis RUN 0.0058 0.0259 0.0363
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0012 0.0026
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0114 0.2012
Loa Loa (eye worm) hypothetical protein 0.0638 0.3953 0.4891
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0564 0.8822
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0017
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0569 0.2596
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0569 0.8904
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.001 0.0046
Echinococcus granulosus peregrin 0.0031 0.0086 0.0189
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0013
Entamoeba histolytica hypothetical protein 0.0022 0.0032 0.0445
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0301 0.1806 0.2235
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0396 0.049
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0032 0.0183
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0183 0.0256
Schistosoma mansoni loxhd1 0.0058 0.0259 0.0363
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0302 0.0423
Brugia malayi photoreceptor-specific nuclear receptor 0.0638 0.3953 0.3953
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0638 0.3953 0.4891
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0564 0.8822
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0072 0.0157
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0639 1
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0569 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0259 0.0321
Brugia malayi Steroid receptor seven-up type 2 0.0638 0.3953 0.3953
Echinococcus multilocularis musashi 0.0026 0.0058 0.0081
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.017 0.0373
Schistosoma mansoni nuclear hormone receptor 0.0638 0.3953 0.5532
Loa Loa (eye worm) hypothetical protein 0.0638 0.3953 0.4891
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0043 0.0748
Brugia malayi PXA domain containing protein 0.0019 0.0009 0.0009
Plasmodium falciparum LCCL domain-containing protein 0.0058 0.0259 0.6975
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0114 0.016
Loa Loa (eye worm) hypothetical protein 0.0361 0.2191 0.2711
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0208 0.0949
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0098 0.067
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0009 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0183
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.001 0.0176
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0009 0.0013
Echinococcus multilocularis nuclear receptor nhr 48 0.0301 0.1806 0.2528
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0113 0.0516
Echinococcus granulosus jumonji domain containing protein 0.004 0.0143 0.0313
Loa Loa (eye worm) hypothetical protein 0.0638 0.3953 0.4891
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0032 0.0183
Loa Loa (eye worm) hypothetical protein 0.0567 0.35 0.433
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0114 0.016
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0569 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0831 0.1027
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0012 0.0012
Brugia malayi Pre-SET motif family protein 0.0204 0.119 0.119
Echinococcus granulosus chromobox protein 2 0.0022 0.0032 0.007
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.001 0.0023
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0569 0.0704
Loa Loa (eye worm) hypothetical protein 0.0337 0.2036 0.2519
Schistosoma mansoni coup transcription factor 0.0638 0.3953 0.5532
Onchocerca volvulus 0.0049 0.0199 0.0465
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.001 0.0014
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0073 0.3285
Schistosoma mansoni lamin 0.0026 0.0058 0.0081
Echinococcus multilocularis peregrin 0.0031 0.0086 0.0121
Loa Loa (eye worm) hypothetical protein 0.0075 0.0368 0.0456
Loa Loa (eye worm) inositol-1 0.0036 0.012 0.0149
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0012 0.0015
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0569 0.1245
Loa Loa (eye worm) hypothetical protein 0.0038 0.0129 0.016
Schistosoma mansoni ap endonuclease 0.0018 0.0007 0.001
Echinococcus granulosus FTZ F1 alpha 0.0638 0.3953 0.8651
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0047 0.1106
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0073 0.1175
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0032 0.0183
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0121 0.0169
Loa Loa (eye worm) hypothetical protein 0.0638 0.3953 0.4891
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.004
Brugia malayi jmjC domain containing protein 0.0036 0.0122 0.0122
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0638 0.3953 0.5532
Loa Loa (eye worm) hypothetical protein 0.0111 0.0594 0.0735
Brugia malayi ecdysteroid receptor 0.0638 0.3953 0.3953
Loa Loa (eye worm) hypothetical protein 0.0301 0.1806 0.2235
Brugia malayi nuclear receptor NHR-88 0.0301 0.1806 0.1806
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0266 0.0329
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0302 0.0661
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0121 0.055
Mycobacterium leprae conserved hypothetical protein 0.002 0.0015 0.0241
Brugia malayi chromobox protein homolog 3 0.005 0.0205 0.0205
Leishmania major DNA polymerase kappa, putative 0.0019 0.001 0.0046
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0073 0.1826
Onchocerca volvulus 0.0035 0.0114 0.0252
Onchocerca volvulus 0.0638 0.3953 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0208 0.0257
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.017 0.0777
Loa Loa (eye worm) DR-78 0.0301 0.1806 0.2235
Mycobacterium ulcerans hypothetical protein 0.0024 0.0043 0.0748
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0638 0.3953 0.4891
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.001 0.0046
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0121 0.0169
Echinococcus multilocularis neuropeptide s receptor 0.0463 0.2839 0.3973
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.012 0.0168
Leishmania major DNA polymerase eta, putative 0.0019 0.001 0.0046
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0072 0.0089
Toxoplasma gondii thioredoxin reductase 0.0046 0.0185 0.5019
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.012 0.0831
Loa Loa (eye worm) hypothetical protein 0.0042 0.0156 0.0193
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0032 0.0183
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0073 0.0484
Echinococcus granulosus single minded 2 0.0035 0.0114 0.025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0072 0.0475
Echinococcus multilocularis chromobox protein 1 0.008 0.0396 0.0554
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0121 0.0833
Echinococcus granulosus zinc finger protein 0.0019 0.0012 0.0026
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.035 0.0765
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0301 0.1806 0.2528
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0185 0.4923
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0114 0.016

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) = 18.6 % Cytotoxicity against mouse RAW264.7 cells at 10 uM after 20 hrs by MTT assay ChEMBL. 18790649
Inhibition (binding) = 0 % Inhibition of human synovial recombinant group 2A sPLA2 at 10 uM ChEMBL. 18790649
Inhibition (functional) = 66.8 % Inhibition of LPS-stimulated PGE2 production in mouse RAW264.7 cells at 10 uM after 20 hrs by radioimmunoassay ChEMBL. 18790649

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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