Detailed information for compound 1051744

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 410.532 | Formula: C22H26N4O2S
  • H donors: 1 H acceptors: 2 LogP: 3.1 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc2c(c1)sc(c2C)CN1CCN(CC1)C(=O)Nc1cccnc1
  • InChi: 1S/C22H26N4O2S/c1-3-28-18-6-7-19-16(2)21(29-20(19)13-18)15-25-9-11-26(12-10-25)22(27)24-17-5-4-8-23-14-17/h4-8,13-14H,3,9-12,15H2,1-2H3,(H,24,27)
  • InChiKey: NJYYBMQJKYXOMU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum glutathione reductase 0.0038 0.015 0.0774
Brugia malayi hypothetical protein 0.0121 0.0672 0.1233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Brugia malayi RNA binding protein 0.0187 0.1092 0.2006
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0108 0.0592 0.1668
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0302
Toxoplasma gondii thioredoxin reductase 0.0038 0.015 0.0462
Brugia malayi nuclear hormone receptor 0.0019 0.003 0.0055
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.015 0.0221
Plasmodium vivax serine-repeat antigen (SERA) 0.0057 0.0268 0.1872
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0072 0.0364 0.0669
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0143
Trypanosoma cruzi cysteine peptidase, putative 0.0288 0.1723 0.3126
Echinococcus granulosus microtubule associated protein 2 0.0682 0.4208 0.7724
Onchocerca volvulus 0.0386 0.2345 0.5346
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0499 0.0866
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0164 0.0302
Giardia lamblia Cathepsin B precursor 0.0057 0.0268 0.044
Loa Loa (eye worm) cysteine protease 0.0196 0.1144 0.2101
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0092 0.0144
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0057 0.0268 0.1872
Brugia malayi cathepsin B-like cysteine proteinase 0.0878 0.5445 1
Toxoplasma gondii cathepsin CPC1 0.0057 0.0268 0.1118
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.003 0.0031
Brugia malayi nuclear receptor RXR 0.0019 0.003 0.0055
Onchocerca volvulus 0.0196 0.1144 0.2572
Echinococcus granulosus cathepsin l1 0.0196 0.1144 0.2081
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0092 0.0138
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0458 0.1657
Brugia malayi Papain family cysteine protease containing protein 0.0113 0.0623 0.1145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0207 0.0379
Schistosoma mansoni tyrosinase precursor 0.0386 0.2345 0.4292
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0181 0.1056
Onchocerca volvulus 0.0049 0.0218 0.0435
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.003 0.0055
Loa Loa (eye worm) RNA binding protein 0.0187 0.1092 0.2006
Brugia malayi conserved hypotetical protein 0.0019 0.003 0.0055
Plasmodium vivax unspecified product 0.0056 0.0265 0.1841
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0164 0.0278
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.003 0.0031
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0164 0.0278
Schistosoma mansoni alpha glucosidase 0.0072 0.0364 0.0646
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Brugia malayi hypothetical protein 0.0025 0.0067 0.0123
Trypanosoma cruzi cruzipain precursor, putative 0.0056 0.0265 0.0433
Schistosoma mansoni lamin 0.0027 0.0078 0.0119
Onchocerca volvulus Cathepsin L homolog 0.0196 0.1144 0.2572
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.0499 0.0916
Plasmodium vivax unspecified product 0.0057 0.0268 0.1872
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0207 0.0193
Onchocerca volvulus 0.004 0.0164 0.031
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0383 0.068
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0623 0.1097
Schistosoma mansoni hypothetical protein 0.0102 0.055 0.0989
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0164 0.0278
Trichomonas vaginalis sucrase-isomaltase, putative 0.0072 0.0364 0.0618
Giardia lamblia Cathepsin L-like protease 0.0057 0.0268 0.044
Echinococcus granulosus jumonji domain containing protein 0.004 0.0163 0.0275
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0499 0.0865
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0164 0.031
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0057 0.0268 0.1872
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0164 0.0278
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0056 0.0265 0.0487
Loa Loa (eye worm) hypothetical protein 0.0049 0.0222 0.0407
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0078 0.0143
Brugia malayi cathepsin Z-like cysteine proteinase 0.0057 0.0268 0.0493
Loa Loa (eye worm) hypothetical protein 0.0056 0.0265 0.0487
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0218 0.0377
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.003 0.0017
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.0499 0.0486
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0057 0.0268 0.1872
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0072 0.0364 0.165
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.003 0.0055
Schistosoma mansoni hypothetical protein 0.0036 0.0134 0.0223
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0057 0.0268 0.1872
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0164 0.0302
Echinococcus granulosus cathepsin L 0.0057 0.0268 0.047
Schistosoma mansoni alpha-glucosidase 0.0279 0.1671 0.3053
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0164 0.0302
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0164 0.0151
Onchocerca volvulus 0.0196 0.1144 0.2572
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0152 0.087 0.4565
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0164 0.0278
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0134 0.0223
Schistosoma mansoni tar DNA-binding protein 0.0187 0.1092 0.1986
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0092 0.0144
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0164 0.0278
Loa Loa (eye worm) hypothetical protein 0.0089 0.0471 0.0865
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0164 0.0278
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0876 0.5435 1
Onchocerca volvulus Huntingtin homolog 0.0121 0.0672 0.1481
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.0079 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0164 0.0302
Brugia malayi hypothetical protein 0.0021 0.0044 0.0082
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0364 0.0618
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0079 0.009
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0458 0.1657
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Plasmodium falciparum cysteine proteinase falcipain 1 0.0113 0.0623 0.5167
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0164 0.031
Brugia malayi cathepsin L-like cysteine proteinase 0.0057 0.0268 0.0493
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0181 0.0631
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0044 0.0057
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.003 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0164 0.0302
Schistosoma mansoni hypothetical protein 0.0047 0.0207 0.0356
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0194 0.0333
Leishmania major trypanothione reductase 0.0038 0.015 0.0651
Brugia malayi hypothetical protein 0.0016 0.0011 0.0021
Echinococcus granulosus neuropeptide s receptor 0.0456 0.2784 0.5101
Loa Loa (eye worm) hypothetical protein 0.0057 0.0268 0.0493
Onchocerca volvulus 0.0196 0.1144 0.2572
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0134 0.0223
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0057 0.0268 0.047
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0458 0.1657
Echinococcus multilocularis neutral alpha glucosidase AB 0.0072 0.0364 0.0351
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0164 0.0302
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0181 0.0631
Schistosoma mansoni cathepsin S (C01 family) 0.0057 0.0268 0.047
Brugia malayi Glycosyl hydrolases family 31 protein 0.0072 0.0364 0.0669
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0164 0.0278
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Brugia malayi jmjC domain containing protein 0.0094 0.0505 0.0927
Giardia lamblia Encystation-specific protease 0.0057 0.0268 0.044
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Brugia malayi PHD-finger family protein 0.0029 0.0092 0.0169
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0386 0.2345 0.4307
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0108 0.0592 0.2177
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0057 0.0268 0.044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0196 0.1144 0.206
Leishmania major hypothetical protein, conserved 0.0025 0.0067 0.0198
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.013 0.0215
Loa Loa (eye worm) hypothetical protein 0.0021 0.0044 0.0082
Brugia malayi MH1 domain containing protein 0.0016 0.0013 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0164 0.0302
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0013 0.0025
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0057 0.0268 0.047
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0079 0.009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.003 0.0031
Schistosoma mansoni DNA polymerase eta 0.0019 0.003 0.0031
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0847 0.1555
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0113 0.0623 0.3224
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0057 0.0268 0.044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0268 0.044
Echinococcus multilocularis musashi 0.0027 0.0078 0.0064
Entamoeba histolytica cysteine proteinase 2 0.0113 0.0623 0.1097
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.003 0.0055
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0113 0.0623 0.1123
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.0499 0.0916
Plasmodium falciparum serine repeat antigen 8 0.0057 0.0268 0.1872
Entamoeba histolytica cysteine protease, putative 0.0057 0.0268 0.044
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.003 0.0017
Brugia malayi hypothetical protein 0.0051 0.0234 0.0431
Echinococcus granulosus tar DNA binding protein 0.0187 0.1092 0.1986
Chlamydia trachomatis dihydrofolate reductase 0.0044 0.0188 0.5
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0268 0.047
Trypanosoma cruzi cysteine proteinase, putative 0.0113 0.0623 0.1095
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0152 0.087 0.4455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Entamoeba histolytica cysteine protease, putative 0.0196 0.1144 0.206
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0471 0.0843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0302
Brugia malayi nuclear receptor RXR 0.0021 0.0044 0.0082
Brugia malayi Cathepsin L-like precursor 0.0196 0.1144 0.2101
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.003 0.0031
Onchocerca volvulus 0.0057 0.0268 0.0551
Entamoeba histolytica cysteine proteinase, putative 0.0139 0.0789 0.1404
Echinococcus multilocularis cysteine protease 0.0196 0.1144 0.1132
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0044 0.0082
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0268 0.0493
Toxoplasma gondii preprocathepsin c precursor, putative 0.0057 0.0268 0.1118
Echinococcus granulosus histone lysine methyltransferase setb 0.0089 0.0471 0.0843
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0876 0.5435 1
Plasmodium vivax SET domain protein, putative 0.0089 0.0471 0.3753
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0364 0.0618
Brugia malayi MH1 domain containing protein 0.0016 0.0013 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0139 0.0789 0.1404
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Loa Loa (eye worm) hypothetical protein 0.0878 0.5445 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0057 0.0268 0.1872
Trypanosoma cruzi cysteine protease, putative 0.0113 0.0623 0.1095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0196 0.1144 0.206
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Schistosoma mansoni tyrosinase precursor 0.0386 0.2345 0.4292
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0164 0.0302
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.003 0.0017
Trypanosoma brucei trypanothione reductase 0.0038 0.015 0.0651
Loa Loa (eye worm) hypothetical protein 0.0196 0.1144 0.2101
Brugia malayi ecdysteroid receptor 0.004 0.0164 0.0302
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0164 0.0302
Plasmodium falciparum serine repeat antigen 7 0.0057 0.0268 0.1872
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0057 0.0268 0.1872
Echinococcus granulosus neutral alpha glucosidase AB 0.0072 0.0364 0.0646
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.0268 0.044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0164 0.0302
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0079 0.009
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0311 0.1869 1
Brugia malayi nuclear receptor NHR-88 0.0019 0.003 0.0055
Plasmodium falciparum serine repeat antigen 1 0.0057 0.0268 0.1872
Brugia malayi Cathepsin L-like precursor 0.0196 0.1144 0.2101
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0181 0.0308
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0057 0.0268 0.044
Brugia malayi nuclear hormone receptor 0.004 0.0164 0.0302
Echinococcus granulosus cathepsin l1 0.0139 0.0789 0.1428
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0878 0.5445 1
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0201 0.0316
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0164 0.0302
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0505 0.0905
Trichomonas vaginalis maltase-glucoamylase, putative 0.0072 0.0364 0.0618
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0878 0.5445 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0164 0.0302
Plasmodium vivax unspecified product 0.0113 0.0623 0.5167
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.013 0.0117
Schistosoma mansoni cathepsin C 0.0057 0.0268 0.047
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0196 0.1144 0.206
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.009
Giardia lamblia PHD finger protein 15 0.0029 0.0092 0.0114
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0051 0.0234 0.0377
Plasmodium falciparum serine repeat antigen 5 0.0057 0.0268 0.1872
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Entamoeba histolytica cysteine proteinase, putative 0.0196 0.1144 0.206
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0364 0.0618
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.003 0.0031
Onchocerca volvulus 0.0196 0.1144 0.2572
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Echinococcus granulosus cathepsin L cysteine proteinase 0.0196 0.1144 0.2081
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0164 0.0278
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0876 0.5435 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0079 0.0146
Echinococcus granulosus peregrin 0.0032 0.0114 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0164 0.0302
Schistosoma mansoni intermediate filament proteins 0.0027 0.0078 0.0119
Echinococcus granulosus lamin dm0 0.0027 0.0078 0.0119
Schistosoma mansoni hypothetical protein 0.0047 0.0207 0.0356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0196 0.1144 0.206
Echinococcus multilocularis microtubule associated protein 2 0.0682 0.4208 0.4201
Brugia malayi cathepsin F-like cysteine proteinase 0.0056 0.0265 0.0487
Leishmania major alpha glucosidase II subunit, putative 0.0072 0.0364 0.1815
Onchocerca volvulus 0.0139 0.0789 0.1753
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0268 0.044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Giardia lamblia Cathepsin L-like protease 0.0057 0.0268 0.044
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0164 0.0151
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0364 0.0618
Loa Loa (eye worm) hypothetical protein 0.0139 0.0789 0.1449
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0164 0.0278
Brugia malayi Papain family cysteine protease containing protein 0.0113 0.0623 0.1145
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0164 0.0278
Brugia malayi Nuclear hormone receptor E75 0.0019 0.003 0.0055
Onchocerca volvulus 0.0108 0.0592 0.1297
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0364 0.0617
Giardia lamblia Cathepsin B precursor 0.0311 0.1869 0.3403
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0207 0.0379
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.0499 0.1082
Schistosoma mansoni tar DNA-binding protein 0.0187 0.1092 0.1986
Trypanosoma cruzi cysteine proteinase, putative 0.0113 0.0623 0.1095
Loa Loa (eye worm) tyrosinase 1 0.0386 0.2345 0.4307
Loa Loa (eye worm) hypothetical protein 0.0021 0.0044 0.0082
Echinococcus multilocularis lysosomal alpha glucosidase 0.0325 0.1956 0.1945
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0231 0.1368 0.247
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.003 0.0031
Plasmodium vivax glutathione reductase, putative 0.0038 0.015 0.0774
Onchocerca volvulus 0.0386 0.2345 0.5346
Schistosoma mansoni alpha-glucosidase 0.0279 0.1671 0.3053
Brugia malayi intermediate filament protein 0.0027 0.0078 0.0143
Trypanosoma brucei cysteine peptidase C (CPC) 0.0311 0.1869 1
Leishmania major cathepsin L-like protease 0.0288 0.1723 0.9203
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0196 0.1144 0.206
Echinococcus granulosus intermediate filament protein 0.0027 0.0078 0.0119
Brugia malayi Cathepsin L-like precursor 0.0139 0.0789 0.1449
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0139 0.0789 0.1404
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0302
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0623 0.1097
Echinococcus multilocularis cathepsin L 0.0113 0.0623 0.0611
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0067 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0268 0.044
Onchocerca volvulus 0.0027 0.0078 0.011
Loa Loa (eye worm) hypothetical protein 0.0057 0.0268 0.0493
Brugia malayi Cathepsin L-like precursor 0.0139 0.0789 0.1449
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0196 0.1144 0.206
Schistosoma mansoni cathepsin F (C01 family) 0.0196 0.1144 0.2081
Loa Loa (eye worm) hypothetical protein 0.0056 0.0265 0.0487
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.2784 0.2774
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0876 0.5435 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0194 0.0333
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0196 0.1144 0.2101
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0057 0.0268 0.1872
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0164 0.0151
Brugia malayi Cathepsin L-like precursor 0.0196 0.1144 0.2101
Onchocerca volvulus Huntingtin homolog 0.0121 0.0672 0.1481
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0878 0.5445 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0153 0.014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.045 0.0805
Brugia malayi hypothetical protein 0.0036 0.0134 0.0247
Giardia lamblia Kinase, PLK 0.0093 0.0499 0.0866
Loa Loa (eye worm) fibroinase 0.0196 0.1144 0.2101
Plasmodium falciparum serine repeat antigen 3 0.0057 0.0268 0.1872
Echinococcus multilocularis lysosomal alpha glucosidase 0.0325 0.1956 0.1945
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0092 0.0232
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0364 0.0618
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.015 0.0464
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0113 0.0623 0.1123
Loa Loa (eye worm) hypothetical protein 0.0139 0.0789 0.1449
Loa Loa (eye worm) hypothetical protein 0.0021 0.0044 0.0082
Onchocerca volvulus 0.0188 0.1094 0.2456
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0458 0.1657
Echinococcus multilocularis cathepsin L cysteine protease 0.0196 0.1144 0.1132
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0187 0.1092 0.2006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0164 0.0278
Brugia malayi Bromodomain containing protein 0.0032 0.0114 0.021
Echinococcus granulosus dna polymerase kappa 0.0019 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0164 0.0151
Giardia lamblia Cysteine protease 0.0057 0.0268 0.044
Echinococcus multilocularis cathepsin b 0.0878 0.5445 0.5438
Onchocerca volvulus 0.0196 0.1144 0.2572
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0164 0.0151
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.0499 0.2546
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0458 0.1657
Entamoeba histolytica cysteine protease, putative 0.0057 0.0268 0.044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0113 0.0623 0.3224
Brugia malayi hypothetical protein 0.0021 0.0044 0.0082
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.0079 0.0266
Brugia malayi Common central domain of tyrosinase family protein 0.0386 0.2345 0.4307
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0057 0.0268 0.044
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0057 0.0268 0.1872
Loa Loa (eye worm) hypothetical protein 0.0021 0.0044 0.0082
Echinococcus granulosus GPCR family 2 0.0047 0.0207 0.0356
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0623 0.1097
Entamoeba histolytica hypothetical protein 0.0057 0.0268 0.044
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Echinococcus granulosus lysosomal alpha glucosidase 0.0325 0.1956 0.3577
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0158 0.0847
Schistosoma mansoni thyroid hormone receptor 0.004 0.0164 0.0278
Echinococcus granulosus cathepsin b 0.0878 0.5445 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.0519 0.1894
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0268 0.0551
Brugia malayi jmjC domain containing protein 0.0035 0.013 0.0239
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0089 0.0471 0.0843
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0153 0.0258
Giardia lamblia Cathepsin L precursor 0.0057 0.0268 0.044
Brugia malayi hypothetical protein 0.0298 0.1788 0.3284
Brugia malayi Pre-SET motif family protein 0.062 0.382 0.7016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0196 0.1144 0.206
Entamoeba histolytica hypothetical protein 0.0036 0.0134 0.0192
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0057 0.0268 0.1872
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0164 0.0278
Brugia malayi hypothetical protein 0.0019 0.003 0.0055
Brugia malayi glutathione reductase 0.0038 0.015 0.0276
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0057 0.0268 0.0493
Mycobacterium tuberculosis Probable reductase 0.0087 0.0458 0.1657
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0302
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0196 0.1144 0.206
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0164 0.0151
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0876 0.5435 1
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.055 0.1011
Entamoeba histolytica cysteine protease, putative 0.0057 0.0268 0.044
Onchocerca volvulus 0.0196 0.1144 0.2572
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Plasmodium vivax vivapain-2 0.0196 0.1144 1
Mycobacterium ulcerans thymidylate synthase 0.0108 0.0592 0.2177
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0057 0.0268 0.044
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0499 0.0866
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0194 0.0333
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.083 0.1503
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0057 0.0268 0.047
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Echinococcus multilocularis cysteine protease 0.0196 0.1144 0.1132
Entamoeba histolytica cysteine protease, putative 0.0057 0.0268 0.044
Echinococcus granulosus cathepsin l cysteine peptidase 0.0196 0.1144 0.2081
Leishmania major cathepsin L-like protease 0.0196 0.1144 0.6055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0164 0.0302
Loa Loa (eye worm) hypothetical protein 0.0049 0.0218 0.0401
Schistosoma mansoni lamin 0.0027 0.0078 0.0119
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0123
Schistosoma mansoni cathepsin s 0.0056 0.0265 0.0463
Brugia malayi Cathepsin L-like precursor 0.0196 0.1144 0.2101
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.0519 0.1894
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0164 0.0302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0623 0.1097
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0364 0.0618
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0265 0.0433
Echinococcus multilocularis dna polymerase kappa 0.0019 0.003 0.0017
Echinococcus granulosus dna polymerase eta 0.0019 0.003 0.0031
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0428 0.2609 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0194 0.0357
Trypanosoma cruzi cysteine peptidase, putative 0.0113 0.0623 0.1095
Trichomonas vaginalis set domain proteins, putative 0.0706 0.436 0.8012
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0057 0.0268 0.1872
Echinococcus granulosus lamin 0.0027 0.0078 0.0119
Echinococcus multilocularis muscleblind protein 1 0.0147 0.0839 0.0826
Brugia malayi ecdysone receptor 0.0019 0.003 0.0055
Treponema pallidum fructose-bisphosphate aldolase 0.0876 0.5435 0.5
Loa Loa (eye worm) hypothetical protein 0.0139 0.0789 0.1449
Schistosoma mansoni cathepsin F (C01 family) 0.0196 0.1144 0.2081
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0113 0.0623 0.1095
Onchocerca volvulus 0.0386 0.2345 0.5346
Loa Loa (eye worm) hypothetical protein 0.0029 0.0092 0.0169
Echinococcus multilocularis tar DNA binding protein 0.0187 0.1092 0.108
Loa Loa (eye worm) ctsf protein 0.0196 0.1144 0.2101
Giardia lamblia Fructose-bisphosphate aldolase 0.0876 0.5435 1
Onchocerca volvulus 0.0089 0.0471 0.1018
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0057 0.0268 0.044
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Onchocerca volvulus 0.0196 0.1144 0.2572
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0057 0.0268 0.044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0044 0.0082
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0089 0.0471 0.0458
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0079 0.009
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0302
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0878 0.5445 1
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0163 0.015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Echinococcus multilocularis lamin 0.0027 0.0078 0.0064
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0089 0.0471 0.2242
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.013 0.0215
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0207 0.0379
Brugia malayi Pre-SET motif family protein 0.0089 0.0471 0.0865
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0057 0.0268 0.0493
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0325 0.1956 0.3593
Loa Loa (eye worm) TAR-binding protein 0.0187 0.1092 0.2006
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0057 0.0268 0.047
Leishmania major cathepsin L-like protease 0.0196 0.1144 0.6055
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.003 0.0031
Plasmodium falciparum cysteine proteinase falcipain 3 0.0196 0.1144 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0181 0.0278
Schistosoma mansoni nuclear hormone receptor 0.004 0.0164 0.0278
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0428 0.2609 1
Plasmodium vivax vivapain-3 0.0113 0.0623 0.5167
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0057 0.0268 0.044
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.003 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0499 0.0866
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.015 0.0276
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0057 0.0268 0.0493
Echinococcus multilocularis dna polymerase eta 0.0019 0.003 0.0017
Brugia malayi Smad1 0.0016 0.0013 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0623 0.1097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.2784 0.2774
Plasmodium falciparum serine repeat antigen 2 0.0057 0.0268 0.1872
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0057 0.0268 0.1872
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0623 0.1097
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0092 0.0078
Loa Loa (eye worm) hypothetical protein 0.0147 0.0839 0.154
Brugia malayi cathepsin L precursor 0.0057 0.0268 0.0493
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0044 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Schistosoma mansoni microtubule-associated protein tau 0.0682 0.4208 0.7724
Plasmodium falciparum serine repeat antigen 6 0.0057 0.0268 0.1872
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0067 0.0067
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0847 0.1555
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.003 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0196 0.1144 0.206
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0364 0.0618
Giardia lamblia Cathepsin L precursor 0.0057 0.0268 0.044
Entamoeba histolytica cysteine proteinase 1, putative 0.0113 0.0623 0.1097
Schistosoma mansoni hypothetical protein 0.0047 0.0207 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0057 0.0268 0.044
Brugia malayi fibroinase precursor 0.0057 0.0268 0.0493
Brugia malayi Thioredoxin reductase 0.0038 0.015 0.0276
Loa Loa (eye worm) hypothetical protein 0.0056 0.0265 0.0487
Schistosoma mansoni zinc finger protein 0.0019 0.003 0.0031
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0158 0.0236
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0146
Entamoeba histolytica hypothetical protein 0.0036 0.0134 0.0192
Schistosoma mansoni cathepsin F (C01 family) 0.0139 0.0789 0.1428
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Brugia malayi ShTK domain containing protein 0.0386 0.2345 0.4307
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0152 0.087 0.4565
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0499 0.0866
Brugia malayi MH2 domain containing protein 0.0016 0.0013 0.0025
Echinococcus multilocularis tumor protein p63 0.0334 0.2015 0.2004
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0057 0.0268 0.044
Entamoeba histolytica hypothetical protein 0.0036 0.0134 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0268 0.044
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0268 0.047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.2784 0.5101
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0078 0.0143
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.003 0.0031
Giardia lamblia Cathepsin B precursor 0.0311 0.1869 0.3403
Giardia lamblia Cysteine protease 0.0057 0.0268 0.044
Echinococcus multilocularis dihydrofolate reductase 0.0044 0.0188 0.0175
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0089 0.0471 0.0458
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Loa Loa (eye worm) dihydrofolate reductase 0.0044 0.0188 0.0346
Plasmodium falciparum serine repeat antigen 4 0.0057 0.0268 0.1872
Loa Loa (eye worm) transcription factor SMAD2 0.024 0.1425 0.2617
Echinococcus granulosus cathepsin b 0.0878 0.5445 1
Echinococcus multilocularis peregrin 0.0032 0.0114 0.0101
Entamoeba histolytica cysteine protease, putative 0.0057 0.0268 0.044
Brugia malayi hypothetical protein 0.0019 0.003 0.0055
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0194 0.0357
Brugia malayi tailless protein 0.0019 0.003 0.0055
Entamoeba histolytica hypothetical protein 0.0036 0.0134 0.0192
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0364 0.0618
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0302
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0499 0.0893
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0268 0.044
Echinococcus multilocularis thymidylate synthase 0.0108 0.0592 0.0579
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0152 0.087 0.155
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0847 0.1555
Onchocerca volvulus 0.0027 0.0078 0.011
Loa Loa (eye worm) cathepsin B 0.0311 0.1869 0.3433
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0057 0.0268 0.1872
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0057 0.0268 0.044
Loa Loa (eye worm) Smad1 0.0016 0.0013 0.0025
Plasmodium vivax vivapain-2 0.0196 0.1144 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.0499 0.0893
Giardia lamblia Hypothetical protein 0.0057 0.0268 0.044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0471 0.0843
Loa Loa (eye worm) hypothetical protein 0.0386 0.2345 0.4307
Onchocerca volvulus Cathepsin F homolog 0.0196 0.1144 0.2572
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0092 0.0169
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0207 0.0193
Brugia malayi Dihydrofolate reductase 0.0044 0.0188 0.0346
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0152 0.087 0.7455
Loa Loa (eye worm) glutathione reductase 0.0038 0.015 0.0276
Plasmodium falciparum phd finger protein, putative 0.0029 0.0092 0.0232
Schistosoma mansoni nuclear hormone receptor 0.0019 0.003 0.0031
Brugia malayi TAR-binding protein 0.0187 0.1092 0.2006
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0056 0.0265 0.0487
Loa Loa (eye worm) hypothetical protein 0.0102 0.055 0.1011
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.003 0.0056
Brugia malayi MH2 domain containing protein 0.0016 0.0013 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.0196 0.1144 0.2101
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0876 0.5435 1
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0364 0.0617
Toxoplasma gondii cathepsin CPL 0.0196 0.1144 0.5975
Trypanosoma cruzi cysteine peptidase, putative 0.0288 0.1723 0.3126
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.003 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Mycobacterium tuberculosis Hypothetical protein 0.0051 0.0234 0.0791
Loa Loa (eye worm) hypothetical protein 0.0057 0.0268 0.0493
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0057 0.0268 0.044
Giardia lamblia Hypothetical protein 0.0057 0.0268 0.044
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0164 0.0151
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.003 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0196 0.1144 0.206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0268 0.044
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0057 0.0268 0.044
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0499 0.0866
Giardia lamblia Cysteine protease 0.0057 0.0268 0.044
Echinococcus granulosus cathepsin L cysteine protease 0.0113 0.0623 0.1123
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0285 0.0524
Leishmania major cysteine peptidase A (CPA) 0.0196 0.1144 0.6055
Echinococcus multilocularis lamin dm0 0.0027 0.0078 0.0064
Plasmodium vivax serine-repeat antigen (SERA) 0.0057 0.0268 0.1872
Giardia lamblia Cathepsin B precursor 0.0057 0.0268 0.044
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0057 0.0268 0.044
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0044 0.0057
Onchocerca volvulus 0.0706 0.436 1
Echinococcus granulosus FTZ F1 alpha 0.004 0.0164 0.0278
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0386 0.2345 0.4307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0164 0.0151
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.003 0.0031
Echinococcus multilocularis muscleblind protein 0.0147 0.0839 0.0826
Giardia lamblia Cathepsin B precursor 0.0057 0.0268 0.044
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0013 0.0025
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0078 0.0143
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.003 0.0017
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0164 0.0302
Giardia lamblia Cathepsin L precursor 0.0057 0.0268 0.044
Leishmania major cathepsin L-like protease 0.0196 0.1144 0.6055
Loa Loa (eye worm) hypothetical protein 0.0298 0.1788 0.3284
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0164 0.0302
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0164 0.0151
Plasmodium falciparum thioredoxin reductase 0.0038 0.015 0.0774
Giardia lamblia Cathepsin L precursor 0.0057 0.0268 0.044
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0158 0.0236
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0268 0.0493
Brugia malayi RNA recognition motif domain containing protein 0.0187 0.1092 0.2006
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0079 0.009
Entamoeba histolytica cysteine proteinase, putative 0.0196 0.1144 0.206
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0196 0.1144 0.1132
Loa Loa (eye worm) DR-78 0.0019 0.003 0.0055
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0057 0.0268 0.1872
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0164 0.0302
Brugia malayi thymidylate synthase 0.0108 0.0592 0.1087
Echinococcus granulosus thymidylate synthase 0.0108 0.0592 0.1065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Giardia lamblia Cathepsin B precursor 0.0057 0.0268 0.044
Brugia malayi Cathepsin L-like precursor 0.0056 0.0265 0.0487
Schistosoma mansoni nuclear receptor 0.0019 0.003 0.0031
Brugia malayi cathepsin Z-like cysteine proteinase 0.0057 0.0268 0.0493
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0207 0.0356
Trypanosoma cruzi cysteine peptidase, putative 0.0196 0.1144 0.2056
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0152 0.087 0.7455
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0164 0.0278
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0057 0.0268 0.0493
Toxoplasma gondii cathepsin CPC2 0.0057 0.0268 0.1118
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0499 0.0866
Brugia malayi Muscleblind-like protein 0.0147 0.0839 0.154
Trypanosoma cruzi cruzipain precursor, putative 0.0288 0.1723 0.3126
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0044 0.0188 0.0612
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0302
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0268 0.047
Echinococcus granulosus tumor protein p63 0.0334 0.2015 0.3685
Giardia lamblia Cathepsin L precursor 0.0057 0.0268 0.044
Brugia malayi MH2 domain containing protein 0.024 0.1425 0.2617
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0268 0.044
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Onchocerca volvulus 0.0298 0.1788 0.406
Brugia malayi Cathepsin L-like precursor 0.0196 0.1144 0.2101
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0505 0.0492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0164 0.0302
Schistosoma mansoni cathepsin B (C01 family) 0.0057 0.0268 0.047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0268 0.044
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.003 0.0017
Brugia malayi cathepsin L-like precursor 0.0139 0.0789 0.1449
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0268 0.0493
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.0499 0.0866
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.062 0.382 0.7016
Schistosoma mansoni tar DNA-binding protein 0.0187 0.1092 0.1986
Schistosoma mansoni hypothetical protein 0.0029 0.0092 0.0144
Brugia malayi dihydrofolate reductase family protein 0.0044 0.0188 0.0346
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0113 0.0623 0.1123
Loa Loa (eye worm) ShTK domain-containing protein 0.0386 0.2345 0.4307
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0164 0.0302
Loa Loa (eye worm) ShTK domain-containing protein 0.0386 0.2345 0.4307
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0164 0.0302
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.003 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Trypanosoma cruzi major cysteine proteinase, putative 0.0149 0.0847 0.1509
Loa Loa (eye worm) thymidylate synthase 0.0108 0.0592 0.1087
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.083 0.0817
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0079 0.009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0311 0.1869 0.3417
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0067 0.0067
Schistosoma mansoni nuclear receptor 0.0019 0.003 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0268 0.044
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0234 0.0378
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0364 0.0618
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0044 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0268 0.044
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0164 0.0278
Giardia lamblia Cathepsin L precursor 0.0057 0.0268 0.044
Loa Loa (eye worm) hypothetical protein 0.0149 0.0847 0.1555
Schistosoma mansoni nuclear hormone receptor 0.0019 0.003 0.0031
Onchocerca volvulus 0.0386 0.2345 0.5346
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0196 0.1144 0.2101
Schistosoma mansoni tar DNA-binding protein 0.0187 0.1092 0.1986
Schistosoma mansoni hypothetical protein 0.0047 0.0207 0.0356
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.0519 0.1894
Echinococcus granulosus dihydrofolate reductase 0.0044 0.0188 0.0322
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.009
Brugia malayi nuclear receptor NHR-88 0.004 0.0164 0.0302
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0386 0.2345 0.4307
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0207 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0311 0.1869 0.3403
Brugia malayi cathepsin F-like cysteine proteinase 0.0057 0.0268 0.0493
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.003 0.0055
Echinococcus multilocularis geminin 0.0334 0.2016 0.2006
Leishmania major cathepsin L-like protease 0.0196 0.1144 0.6055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.015 0.0774
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0194 0.0333
Schistosoma mansoni dihydrofolate reductase 0.0044 0.0188 0.0322
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.003 0.0031
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0164 0.0278
Loa Loa (eye worm) hypothetical protein 0.0121 0.0672 0.1233
Brugia malayi Nuclear hormone receptor E75 0.0019 0.003 0.0055
Entamoeba histolytica cysteine protease, putative 0.0113 0.0623 0.1097
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0164 0.031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0876 0.5435 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0194 0.0181
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0302
Schistosoma mansoni hypothetical protein 0.0334 0.2016 0.3688
Loa Loa (eye worm) hypothetical protein 0.0047 0.0207 0.0379
Echinococcus multilocularis cathepsin b 0.0878 0.5445 0.5438
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0164 0.0302
Echinococcus granulosus cysteine protease 0.0113 0.0623 0.1123
Entamoeba histolytica cysteine protease, putative 0.0057 0.0268 0.044
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0181 0.0278
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0499 0.0865
Loa Loa (eye worm) MH2 domain-containing protein 0.024 0.1425 0.2617
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0196 0.1144 0.206
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0108 0.0592 0.1065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0311 0.1869 0.3396
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.003 0.0056
Brugia malayi nuclear receptor NHR-67 0.0019 0.003 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0164 0.0302
Schistosoma mansoni thyroid hormone receptor 0.004 0.0164 0.0278
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.013 0.0215
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0196 0.1144 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.003 0.0055
Brugia malayi Cathepsin L-like precursor 0.0196 0.1144 0.2101
Trypanosoma brucei polo-like protein kinase 0.0093 0.0499 0.2546
Onchocerca volvulus Alhambra homolog 0.0029 0.0092 0.0143
Loa Loa (eye worm) hypothetical protein 0.0147 0.0839 0.154
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0876 0.5435 1
Schistosoma mansoni tar DNA-binding protein 0.0187 0.1092 0.1986
Loa Loa (eye worm) hypothetical protein 0.0057 0.0268 0.0493
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Loa Loa (eye worm) hypothetical protein 0.0121 0.0672 0.1233
Schistosoma mansoni hypothetical protein 0.0334 0.2016 0.3688
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0458 0.1113
Brugia malayi steroid hormone receptor 0.004 0.0164 0.0302
Echinococcus multilocularis cathepsin L 0.0057 0.0268 0.0255
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0268 0.047
Loa Loa (eye worm) hypothetical protein 0.0057 0.0268 0.0493
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0196 0.1144 0.206
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0092 0.0138
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0804 0.1455
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0164 0.0278
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0164 0.0302
Trypanosoma brucei glucosidase, putative 0.0072 0.0364 0.1815
Leishmania major cathepsin L-like protease 0.0288 0.1723 0.9203
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.013 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0876 0.5435 1
Loa Loa (eye worm) acetyltransferase 0.0146 0.083 0.1524
Trypanosoma cruzi cysteine peptidase, putative 0.0288 0.1723 0.3126
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0044 0.0188 0.0612
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0386 0.2345 0.4307
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Plasmodium falciparum serine repeat antigen 9 0.0057 0.0268 0.1872
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0079 0.0266
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0268 0.044
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0044 0.0082
Schistosoma mansoni kinase 0.0047 0.0209 0.0361
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0044 0.0057
Leishmania major cathepsin L-like protease 0.0196 0.1144 0.6055
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Schistosoma mansoni coup transcription factor 0.004 0.0164 0.0278
Toxoplasma gondii cathepsin B 0.0311 0.1869 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0139 0.0789 0.1449
Giardia lamblia Cathepsin B precursor 0.0311 0.1869 0.3403
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0134 0.0121
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0471 0.0843
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.003 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0499 0.0866
Echinococcus granulosus cathepsin L 0.0113 0.0623 0.1123
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.009
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0201 0.0316
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0876 0.5435 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0056
Brugia malayi Glycosyl hydrolases family 31 protein 0.0325 0.1956 0.3593
Echinococcus multilocularis cathepsin L cysteine protease 0.0196 0.1144 0.1132
Giardia lamblia Cysteine protease 0.0057 0.0268 0.044
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.083 0.1524
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0194 0.0333
Onchocerca volvulus Cathepsin L homolog 0.0196 0.1144 0.2572
Leishmania major cathepsin L-like protease 0.0288 0.1723 0.9203
Loa Loa (eye worm) hypothetical protein 0.0386 0.2345 0.4307
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0268 0.047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0288 0.1723 0.9203
Plasmodium vivax vivapain-1 0.0113 0.0623 0.5167
Echinococcus granulosus geminin 0.0334 0.2016 0.3688
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0196 0.1144 1
Echinococcus granulosus muscleblind protein 0.0147 0.0839 0.1519
Echinococcus multilocularis GPCR, family 2 0.0047 0.0207 0.0193
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0196 0.1144 0.1132
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0428 0.2609 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.0519 0.1365
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0194 0.0181
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0878 0.5445 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0268 0.0493
Giardia lamblia Cathepsin B precursor 0.0057 0.0268 0.044

Activities

Activity type Activity value Assay description Source Reference
Ratio (binding) < 10 /M/s Ratio of Kinact to Ki for histidine6-tagged rat FAAH ChEMBL. 19386497
Ratio (binding) = 14 /M/s Ratio of Kinact to Ki for histidine6-tagged human FAAH ChEMBL. 19386497

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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