Detailed information for compound 1098198

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 333.344 | Formula: C11H23N7O5
  • H donors: 6 H acceptors: 5 LogP: -1.01 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: ONC(=O)[C@@H](NC(=O)[C@H](C(C)C)N)CCCNC(=N)N[N+](=O)[O-]
  • InChi: 1S/C11H23N7O5/c1-6(2)8(12)10(20)15-7(9(19)17-21)4-3-5-14-11(13)16-18(22)23/h6-8,21H,3-5,12H2,1-2H3,(H,15,20)(H,17,19)(H3,13,14,16)/t7-,8-/m0/s1
  • InChiKey: CEUNNLWAKWOBCW-YUMQZZPRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0022 0.0022
Brugia malayi Pre-SET motif family protein 0.0204 0.1395 0.1843
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0056 0.0216
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.012 0.0784 0.3032
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0041 0.0212 0.0212
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0254 0.1761 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0304 0.2121 0.2121
Brugia malayi hypothetical protein 0.0041 0.0212 0.028
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0046 0.0246 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0292
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.012 0.0784 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0279 0.108
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.012 0.0784 1
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.092 0.3558
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0172 0.0941
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0041 0.0212 0.0212
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0041 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0036
Trypanosoma brucei heat shock protein, putative 0.0044 0.0237 0.3029
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.0000001956 0.0000001956
Trypanosoma cruzi heat shock protein 85, putative 0.0044 0.0237 0.3029
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0279 0.108
Toxoplasma gondii Hsp90 domain-containing protein 0.0168 0.1137 0.8993
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Echinococcus granulosus heat shock protein 0.0044 0.0237 0.0237
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0187 0.9989
Mycobacterium ulcerans hypothetical protein 0.005 0.0279 0.108
Echinococcus granulosus survival motor neuron protein 1 0.0271 0.1883 0.1883
Schistosoma mansoni endoplasmin 0.0044 0.0237 0.0237
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0041 0.0212 0.2705
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.0247
Brugia malayi Patched protein homolog 1 0.0013 0.0009 0.0011
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0032 0.0148 0.0195
Onchocerca volvulus 0.0041 0.0212 0.0334
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0041 0.0212 0.028
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0046 0.0246 0.0246
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0041 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0067 0.0404 0.0404
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0339 0.2682
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0279 0.108
Toxoplasma gondii heat shock protein HSP90 0.0044 0.0237 0.1878
Loa Loa (eye worm) hypothetical protein 0.0091 0.0577 0.0763
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0041 0.0212 0.028
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0041 0.0212 0.0212
Trichomonas vaginalis pten, drome, putative 0.0041 0.0212 0.082
Brugia malayi intermediate filament protein 0.0032 0.0148 0.0195
Brugia malayi Protein-tyrosine phosphatase 1 0.0041 0.0212 0.028
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0279 0.108
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0368 0.2584 0.3414
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0577 0.2234
Toxoplasma gondii patched family protein 0.0013 0.0009 0.0067
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0022 0.0085
Schistosoma mansoni patched 1 0.0091 0.0577 0.0577
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0022 0.0279
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0067 0.0404 0.0534
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0187 0.1645
Schistosoma mansoni hypothetical protein 0.0088 0.0553 0.0553
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0218 0.0842
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0046 0.0246 0.0246
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.012 0.0784 0.3032
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0148 0.0195
Plasmodium falciparum endoplasmin, putative 0.0032 0.0149 0.131
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0042 0.0218 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0339 0.4164
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0041 0.0212 0.0212
Loa Loa (eye worm) endoplasmin 0.0044 0.0237 0.0314
Brugia malayi AMP-binding enzyme family protein 0.005 0.0279 0.0369
Giardia lamblia Heat shock protein HSP 90-alpha 0.0044 0.0237 0.0918
Schistosoma mansoni lamin 0.0032 0.0148 0.0148
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0075 0.0292
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0292
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) patched family protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0056 0.0278
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0041 0.0212 0.028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0075 0.0292
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0022 0.0029
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0099 0.0099
Echinococcus multilocularis 0.0041 0.0212 0.0212
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0015 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0146 0.0973 0.1285
Echinococcus multilocularis GPCR, family 2 0.0067 0.0404 0.0404
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.0973 0.1285
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0041 0.0212 0.0212
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0022 0.0192
Mycobacterium ulcerans heat shock protein 90 0.0042 0.0218 0.0842
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0056 0.2563
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.012 0.0784 0.3032
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0022 0.0085
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Echinococcus multilocularis sentrin specific protease 8 0.0089 0.0564 0.0564
Onchocerca volvulus 0.0032 0.0148 0.0233
Brugia malayi CXXC zinc finger family protein 0.0098 0.0623 0.0823
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0041 0.0212 0.0212
Trypanosoma brucei heat shock protein, putative 0.0044 0.0237 0.3029
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0187 0.0724
Trypanosoma brucei heat shock protein 84, putative 0.003 0.0129 0.1648
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0368 0.2584 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0022 0.0085
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Brugia malayi Patched related family protein 12 0.0013 0.0009 0.0011
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0187 0.0725
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Echinococcus granulosus endoplasmin 0.0042 0.0218 0.0218
Brugia malayi hypothetical protein 0.0114 0.0744 0.0983
Schistosoma mansoni microtubule-associated protein tau 0.0821 0.5877 0.5877
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0015 0.0022 0.0085
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.014 0.014
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0041 0.0212 0.0212
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0022 0.0022
Brugia malayi AMP-binding enzyme family protein 0.005 0.0279 0.0369
Trichomonas vaginalis endoplasmin, putative 0.0032 0.0149 0.0576
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Plasmodium vivax sentrin-specific protease 2, putative 0.0038 0.0187 0.1647
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Loa Loa (eye worm) hypothetical protein 0.0037 0.0187 0.0247
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0022 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0292
Trypanosoma brucei heat shock protein 90, putative 0.0044 0.0237 0.3029
Loa Loa (eye worm) CXXC zinc finger family protein 0.0098 0.0623 0.0823
Loa Loa (eye worm) patched family protein 0.0013 0.0009 0.0011
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0056 0.0216
Entamoeba histolytica peptidase, C54 family 0.0047 0.0254 0.0982
Schistosoma mansoni intermediate filament proteins 0.0032 0.0148 0.0148
Echinococcus multilocularis neuropeptide s receptor 0.055 0.391 0.391
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0339 0.4327
Leishmania major heat shock protein, putative 0.003 0.0129 0.1408
Loa Loa (eye worm) hypothetical protein 0.013 0.0857 0.1133
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0172 0.0941
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0187 0.0725
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.014 0.014
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0738 0.9415
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0339 0.0339
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0041 0.0212 0.0212
Onchocerca volvulus 0.0041 0.0212 0.0334
Plasmodium falciparum cysteine protease ATG4, putative 0.0047 0.0254 0.2231
Onchocerca volvulus 0.0078 0.0482 0.0759
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0022 0.0029
Schistosoma mansoni cpg binding protein 0.0098 0.0623 0.0623
Trypanosoma cruzi Heat shock protein 83, putative 0.0044 0.0237 0.3029
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0075 0.0292
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0187 0.1645
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.014 0.014
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0027 0.0027
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0022 0.0085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0075 0.0292
Echinococcus multilocularis expressed conserved protein 0.02 0.1365 0.1365
Entamoeba histolytica peptidase, C54 family 0.0047 0.0254 0.0982
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Echinococcus multilocularis sterol regulatory element binding protein 0.0091 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Trichomonas vaginalis hypothetical protein 0.0012 0.0001 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0279 0.108
Schistosoma mansoni protein tyrosine phosphatase 0.0046 0.0246 0.0246
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0368 0.2584 0.3414
Loa Loa (eye worm) hypothetical protein 0.0213 0.1462 0.1932
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0041 0.0212 0.2705
Schistosoma mansoni transcription factor btf3 0.0037 0.0184 0.0184
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0041 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0114 0.0745 0.0984
Echinococcus multilocularis heat shock protein 90 0.0038 0.0191 0.0191
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0113 0.0738 0.9415
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0251 0.1739 0.1739
Brugia malayi Patched related family protein 4 0.0013 0.0009 0.0011
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0046 0.0246 0.0246
Schistosoma mansoni cpg binding protein 0.0103 0.0663 0.0663
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0041 0.0212 0.0212
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0041 0.0212 0.2705
Schistosoma mansoni ap endonuclease 0.0019 0.0056 0.0056
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0046 0.0246 0.0246
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0075 0.0292
Brugia malayi Calcitonin receptor-like protein seb-1 0.0213 0.1462 0.1932
Schistosoma mansoni ap endonuclease 0.0019 0.0056 0.0056
Onchocerca volvulus 0.0041 0.0212 0.0334
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0339 0.4327
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0022 0.0279
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0046 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Echinococcus multilocularis protein dispatched 1 0.0104 0.0671 0.0671
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.014 0.014
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0041 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0213 0.1462 0.1932
Trypanosoma brucei heat shock protein, putative 0.0044 0.0237 0.3029
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0038 0.0187 0.1481
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0022 0.0085
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0024 0.0024
Trypanosoma cruzi heat shock protein, putative 0.003 0.0129 0.1648
Brugia malayi Latrophilin receptor protein 2 0.0067 0.0404 0.0534
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0339 0.0448
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Leishmania major basic transcription factor 3a, putative 0.0037 0.0184 0.2127
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0279 0.108
Loa Loa (eye worm) hypothetical protein 0.0158 0.1059 0.14
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0038 0.0187 0.2389
Plasmodium falciparum basic transcription factor 3b, putative 0.0037 0.0184 0.1618
Plasmodium vivax endoplasmin, putative 0.0044 0.0237 0.2088
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1055 0.7569 1
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0041 0.0212 0.028
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0056 0.0712
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.003 0.0129 0.0129
Entamoeba histolytica 90 kDa heat shock protein, putative 0.003 0.0129 0.05
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0022 0.0279
Brugia malayi Endoplasmin precursor 0.0044 0.0237 0.0314
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0089 0.0564 0.2181
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0038 0.0187 0.2171
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0251 0.1739 0.1739
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0251 0.1739 0.1739
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0067 0.0404 0.0534
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Giardia lamblia Protein tyrosine phosphatase 0.0041 0.0212 0.082
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0022 0.0085
Brugia malayi Hsp90 protein 0.003 0.0129 0.0171
Echinococcus multilocularis cysteine protease atg4b 0.012 0.0784 0.0784
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0015 0.0022 0.0085
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.092 1
Entamoeba histolytica hypothetical protein 0.0114 0.0744 0.288
Schistosoma mansoni heat shock protein 0.003 0.0129 0.0129
Echinococcus granulosus heat shock protein 90 0.0044 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0038 0.0187 0.0725
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Onchocerca volvulus 0.0015 0.0022 0.0034
Schistosoma mansoni transcription factor LCR-F1 0.0114 0.0744 0.0744
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0022 0.0192
Loa Loa (eye worm) hypothetical protein 0.0032 0.0144 0.019
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0041 0.0212 0.0212
Onchocerca volvulus 0.0015 0.0022 0.0034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0251 0.1739 0.1739
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0012 0.0000001956 0.00000075685
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0022 0.0085
Echinococcus granulosus Protein patched homolog 1 0.0091 0.0577 0.0577
Loa Loa (eye worm) ICD-1 protein 0.0037 0.0184 0.0243
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0041 0.0212 0.0212
Chlamydia trachomatis deubiquitinase/deneddylase Dub2 0.0038 0.0187 1
Brugia malayi hypothetical protein 0.0013 0.0009 0.0011
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0187 0.1026
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0187 0.0725
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Brugia malayi Muscleblind-like protein 0.0158 0.1059 0.14
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0168 0.1136 0.1136
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Loa Loa (eye worm) patched family protein 0.0013 0.0009 0.0011
Schistosoma mansoni survival motor neuron protein 0.0055 0.0316 0.0316
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Entamoeba histolytica heat shock protein 90, putative 0.0044 0.0237 0.0918
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0279 0.3377
Echinococcus multilocularis heat shock protein 0.0044 0.0237 0.0237
Echinococcus granulosus Niemann Pick C1 protein 0.0304 0.2121 0.2121
Loa Loa (eye worm) hypothetical protein 0.0271 0.1883 0.2488
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0046 0.0246 0.0246
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0000001956 0.0000001956
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0251 0.1739 0.1739
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0339 0.1312
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1055 0.7569 0.7569
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0368 0.2584 1
Loa Loa (eye worm) heat shock protein 75 0.003 0.0129 0.0171
Trypanosoma brucei heat shock protein, putative 0.0044 0.0237 0.3029
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0015 0.0022 0.0238
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Plasmodium vivax SET domain protein, putative 0.0031 0.014 0.1235
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.0247
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0031
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Echinococcus multilocularis cpg binding protein 0.0103 0.0663 0.0663
Echinococcus multilocularis heat shock protein 90 0.0044 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Echinococcus granulosus microtubule associated protein 2 0.0821 0.5877 0.5877
Brugia malayi Myosin head containing protein 0.0013 0.0009 0.0011
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0216 0.1482 0.1482
Onchocerca volvulus 0.0015 0.0022 0.0034
Echinococcus multilocularis muscleblind protein 0.0158 0.1059 0.1059
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0339 0.0339
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Brugia malayi hypothetical protein 0.0041 0.0212 0.028
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0041 0.0212 0.028
Brugia malayi hypothetical protein 0.0041 0.0212 0.028
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Giardia lamblia Grp94/Hsp90 0.0042 0.0218 0.0842
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0041 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Echinococcus granulosus lamin dm0 0.0032 0.0148 0.0148
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0339 0.4327
Echinococcus multilocularis protein patched 0.0091 0.0577 0.0577
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0187 0.0725
Entamoeba histolytica hypothetical protein 0.0114 0.0744 0.288
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.012 0.0784 0.0784
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Echinococcus granulosus GPCR family 2 0.0067 0.0404 0.0404
Echinococcus multilocularis hypothetical protein 0.0041 0.0212 0.0212
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0102 0.09
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0022 0.0029
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0149 0.0576
Entamoeba histolytica transcription factor BTF3, putative 0.0037 0.0184 0.0712
Trypanosoma brucei protein kinase, putative 0.0058 0.0339 0.4327
Plasmodium vivax patched family protein, putative 0.0013 0.0009 0.0075
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0046 0.0246 0.0246
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0114 0.0744 0.0744
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.0247
Echinococcus granulosus expressed conserved protein 0.0131 0.0863 0.0863
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0047 0.0254 0.3237
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0056 0.0056
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0114 0.0744 0.0744
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0022 0.0029
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Loa Loa (eye worm) hypothetical protein 0.005 0.0279 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0339 0.0339
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0142 0.0142
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0187 0.0247
Loa Loa (eye worm) hypothetical protein 0.0031 0.014 0.0186
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0041 0.0212 0.0212
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0292
Schistosoma mansoni hypothetical protein 0.0067 0.0404 0.0404
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0075 0.0292
Trypanosoma brucei heat shock protein 90, putative 0.0044 0.0237 0.3029
Loa Loa (eye worm) hypothetical protein 0.013 0.0857 0.1133
Toxoplasma gondii patched family protein 0.0013 0.0009 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0292
Plasmodium falciparum heat shock protein 90, putative 0.0168 0.1137 1
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0187 0.0725
Echinococcus multilocularis endoplasmin 0.0042 0.0218 0.0218
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0022 0.0173
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.1972 1
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0046 0.0246 0.0246
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0000001956 0.00000075685
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0056 0.0283
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0041 0.0212 0.0212
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Entamoeba histolytica hypothetical protein 0.0114 0.0744 0.288
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0187 0.0725
Echinococcus granulosus heat shock protein 90 0.0038 0.0191 0.0191
Trichomonas vaginalis Sentrin-specific protease, putative 0.0089 0.0564 0.2181
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0037 0.0187 0.0247
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0.0022 0.0238
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0041 0.0212 0.0212
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0279 0.108
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0041 0.0212 0.0212
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Loa Loa (eye worm) histone methyltransferase 0.0031 0.0142 0.0187
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0041 0.0212 0.2496
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0213 0.1458 0.5643
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0113 0.0738 0.2855
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0279 0.1551
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0158 0.1059 0.14
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0022 0.0085
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0339 0.1312
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0279 0.1551
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0279 0.108
Onchocerca volvulus 0.0031 0.014 0.0221
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0042 0.0218 0.2366
Schistosoma mansoni hypothetical protein 0.0067 0.0404 0.0404
Schistosoma mansoni pcd6 interacting protein-related 0.0041 0.0212 0.0212
Onchocerca volvulus 0.0041 0.0212 0.0334
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Echinococcus granulosus neuropeptide s receptor 0.055 0.391 0.391
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0089 0.0564 0.2181
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Trypanosoma brucei transcription factor BTF3, putative 0.0037 0.0184 0.2347
Schistosoma mansoni hypothetical protein 0.0146 0.0973 0.0973
Schistosoma mansoni hypothetical protein 0.0088 0.0553 0.0553
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0339 0.1312
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0038 0.0187 0.2389
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0041 0.0212 0.0212
Brugia malayi protein C24B5.3 0.0013 0.0009 0.0011
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.005 0.0637
Onchocerca volvulus 0.0013 0.0009 0.0013
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Onchocerca volvulus 0.0015 0.0022 0.0034
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0056 0.0216
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0041 0.0212 0.0212
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0067 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0073 0.0448 0.0592
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0056 0.0445
Plasmodium vivax heat shock protein 86, putative 0.0044 0.0237 0.2088
Echinococcus multilocularis lamin dm0 0.0032 0.0148 0.0148
Onchocerca volvulus 4.1 G protein, putative homolog 0.0041 0.0212 0.0334
Onchocerca volvulus 0.0041 0.0212 0.0334
Toxoplasma gondii ATPase, AAA family protein 0.0012 0.0000001956 0.0000015472
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Echinococcus multilocularis neuropeptide receptor A26 0.055 0.391 0.391
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0038 0.0187 0.1481
Onchocerca volvulus 0.0041 0.0212 0.0334
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0208 0.1425 0.1425
Onchocerca volvulus Protein patched homolog 0.0013 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0046 0.0246 0.0246
Echinococcus multilocularis microtubule associated protein 2 0.0821 0.5877 0.5877
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0042 0.0218 0.12
Onchocerca volvulus 0.0368 0.2584 0.4068
Onchocerca volvulus Phospholipase A2 homolog 0.0187 0.127 0.2
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0001 0.0004
Entamoeba histolytica heat shock protein 90, putative 0.0044 0.0237 0.0918
Echinococcus granulosus Niemann Pick C1 protein 0.0213 0.1458 0.1458
Schistosoma mansoni endoplasmin 0.0044 0.0237 0.0237
Loa Loa (eye worm) latrophilin receptor protein 2 0.0067 0.0404 0.0534
Onchocerca volvulus 0.0041 0.0212 0.0334
Brugia malayi Peptidase family C54 containing protein 0.012 0.0784 0.1035
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0022 0.0085
Toxoplasma gondii histone lysine methyltransferase SET1 0.0186 0.1264 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0022 0.0085
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0041 0.0212 0.0212
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0089 0.0564 0.0564
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0168 0.1136 0.4395
Schistosoma mansoni cpg binding protein 0.0103 0.0663 0.0663
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0022 0.0279
Trypanosoma brucei Heat shock protein 83, putative 0.0044 0.0237 0.3029
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0047 0.0254 0.3237
Entamoeba histolytica peptidase, C54 family 0.012 0.0784 0.3032
Loa Loa (eye worm) hypothetical protein 0.0073 0.0448 0.0592
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Brugia malayi CHE-14 protein 0.0091 0.0577 0.0763
Plasmodium vivax basic transcription factor 3b, putative 0.0037 0.0184 0.1618
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0067 0.0404 0.0404
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0022 0.0173
Onchocerca volvulus 0.005 0.0279 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0292
Brugia malayi AMP-binding enzyme family protein 0.005 0.0279 0.0369
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0099 0.0099
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Trypanosoma cruzi heat shock protein 90, putative 0.0044 0.0237 0.3029
Brugia malayi Protein-tyrosine phosphatase 0.0119 0.0779 0.1029
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0022 0.0085
Echinococcus granulosus Peptidase C54 0.012 0.0784 0.0784
Trypanosoma brucei heat shock protein, putative 0.0044 0.0237 0.3029
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0038 0.0191 0.0191
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0117 0.0117
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0046 0.0246 0.0246
Brugia malayi hypothetical protein 0.013 0.0857 0.1133
Onchocerca volvulus 0.0032 0.0148 0.0233
Mycobacterium ulcerans acetyl-CoA synthetase 0.0015 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Brugia malayi Phospholipase A2 family protein 0.0187 0.127 0.1678
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0089 0.0564 0.2181
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0041 0.0212 0.0212
Schistosoma mansoni lamin 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0056 0.0074
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0279 0.3377
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0015 0.0022 0.0085
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0027 0.0027
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0038 0.0187 0.0187
Trypanosoma brucei protein tyrosine phosphatase 1 0.0041 0.0212 0.2705
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0047 0.0254 0.3237
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.1055 0.7569 0.7569
Loa Loa (eye worm) hypothetical protein 0.0187 0.127 0.1678
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0015 0.0022 0.0238
Echinococcus multilocularis transcription factor btf3 0.0037 0.0184 0.0184
Giardia lamblia Sentrin specific protease, putative 0.0038 0.0187 0.0725
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0786 0.562 0.562
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0292
Leishmania major hypothetical protein, conserved 0.0113 0.0738 0.9399
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0187 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0184 0.0712
Trypanosoma cruzi hypothetical protein 0.0089 0.0564 0.7193
Onchocerca volvulus 0.0038 0.0187 0.0295
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0041 0.0212 0.0212
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0251 0.1739 0.1739
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0113 0.0738 0.2855
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0251 0.1739 0.1739
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0187 0.0725
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Echinococcus granulosus sterol regulatory element binding protein 0.0091 0.0577 0.0577
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0000001956 0.0000001956
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0089 0.0564 0.2181
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0041 0.0212 0.0212
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0038 0.0187 0.0187
Echinococcus granulosus sentrin specific protease 1 0.0038 0.0187 0.0187
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0056 0.049
Onchocerca volvulus 0.0041 0.0212 0.0334
Onchocerca volvulus 0.0041 0.0212 0.0334
Brugia malayi hypothetical protein 0.0013 0.0009 0.0011
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0022 0.0173
Mycobacterium ulcerans hypothetical protein 0.0115 0.075 0.2903
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0172 0.0941
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1055 0.7569 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0041 0.0212 0.0212
Leishmania major tyrosine specific protein phosphatase, putative 0.0041 0.0212 0.2496
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1055 0.7569 0.7569
Onchocerca volvulus 0.0055 0.0316 0.0498
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0022 0.0029
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0368 0.2584 1
Echinococcus granulosus protein tyrosine phosphatase n9 0.0041 0.0212 0.0212
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0056 0.0216
Onchocerca volvulus 0.0041 0.0212 0.0334
Toxoplasma gondii exonuclease III APE 0.0019 0.0056 0.0441
Onchocerca volvulus 0.0041 0.0212 0.0334
Echinococcus multilocularis Peptidase C54 0.012 0.0784 0.0784
Loa Loa (eye worm) heat shock protein 90 0.0044 0.0237 0.0314
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0251 0.1739 0.2297
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0099 0.0099
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0041 0.0212 0.0212
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.014 0.014
Loa Loa (eye worm) patched family protein 0.0013 0.0009 0.0011
Chlamydia trachomatis deubiquitinase/deneddylase Dub1 0.0038 0.0187 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0251 0.1739 0.2297
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Onchocerca volvulus 0.0041 0.0212 0.0334
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.092 0.5202
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.012 0.0784 0.3032
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0368 0.2584 1
Plasmodium falciparum heat shock protein 90 0.0044 0.0237 0.2088
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0213 0.1462 0.1932
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0041 0.0212 0.0212
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0368 0.2584 1
Echinococcus granulosus sentrin specific protease 8 0.0089 0.0564 0.0564
Echinococcus multilocularis lamin 0.0032 0.0148 0.0148
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.004 0.0053
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.014 0.014
Onchocerca volvulus 0.0041 0.0212 0.0334
Onchocerca volvulus 0.0041 0.0212 0.0334
Trypanosoma cruzi heat shock protein 85, putative 0.0044 0.0237 0.3029
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0041 0.0212 0.0212
Trichomonas vaginalis heat shock protein, putative 0.0038 0.0191 0.0738
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0148 0.0195
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0056 0.049
Onchocerca volvulus 0.0013 0.0009 0.0013
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0015 0.0022 0.0085
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0187 0.0725
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0339 0.4164
Plasmodium vivax sentrin-specific protease 1, putative 0.0038 0.0187 0.1647
Loa Loa (eye worm) Ulp1 protease 0.0038 0.0187 0.0247
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Schistosoma mansoni hypothetical protein 0.0558 0.3962 0.3962
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0022 0.0085
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0368 0.2584 1
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0022 0.0029
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0000001956 0.00000075685
Brugia malayi Niemann-Pick C1 protein precursor 0.0213 0.1458 0.1927
Trypanosoma cruzi heat shock protein 85, putative 0.0044 0.0237 0.3029
Trypanosoma brucei heat shock protein, putative 0.0044 0.0237 0.3029
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0102 0.0396
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Trypanosoma cruzi heat shock protein 90, putative 0.0038 0.0191 0.2435
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0187 0.0725
Echinococcus granulosus cpg binding protein 0.0103 0.0663 0.0663
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0099 0.0099
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.003 0.0129 0.0203
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0172 0.0941
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0368 0.2584 1
Entamoeba histolytica peptidase, C54 family 0.0047 0.0254 0.0982
Onchocerca volvulus 0.0041 0.0212 0.0334
Onchocerca volvulus 0.0013 0.0009 0.0013
Echinococcus multilocularis survival motor neuron protein 1 0.0271 0.1883 0.1883
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0015 0.0022 0.0085
Onchocerca volvulus 0.0013 0.0009 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0075 0.0292
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0041 0.0212 0.0212
Echinococcus granulosus transcription factor btf3 0.0037 0.0184 0.0184
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0022 0.0279
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0041 0.0212 0.082
Toxoplasma gondii heat shock protein 90, putative 0.0044 0.0237 0.1878
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0067 0.0404 0.0404
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Trichomonas vaginalis replication factor C large subunit, putative 0.0012 0.0000001956 0.00000075685
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0022 0.0085
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0738 0.9415
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0279 0.3035
Brugia malayi Pre-SET motif family protein 0.0031 0.014 0.0186
Echinococcus multilocularis sentrin specific protease 7 0.0168 0.1136 0.1136
Schistosoma mansoni protein tyrosine phosphatase 0.0041 0.0212 0.0212
Onchocerca volvulus 0.0041 0.0212 0.0334
Onchocerca volvulus 0.0041 0.0212 0.0334
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0091 0.0577 0.0763
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0339 0.4327
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0046 0.0246 0.0246
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0047 0.0254 0.3043
Schistosoma mansoni hypothetical protein 0.1389 1 1
Loa Loa (eye worm) protein tyrosine phosphatase 0.0041 0.0212 0.028
Brugia malayi hypothetical protein 0.0271 0.1883 0.2488
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0075 0.0292
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0041 0.0212 0.0212
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Loa Loa (eye worm) hypothetical protein 0.0213 0.1458 0.1927
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.003 0.0129 0.0129
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0056 0.0712
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0056 0.0056
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0041 0.0212 0.0212
Onchocerca volvulus 0.0013 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.005 0.0279 0.0369
Echinococcus multilocularis geminin 0.0558 0.3962 0.3962
Schistosoma mansoni hypothetical protein 0.0088 0.0553 0.0553
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0316 0.0418
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.004 0.0053
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Plasmodium falciparum sentrin-specific protease 1 0.0038 0.0187 0.1647
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Brugia malayi Protein-tyrosine phosphatase 0.0041 0.0212 0.028
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0046 0.0246 0.0246
Echinococcus granulosus neuropeptide receptor A26 0.055 0.391 0.391
Onchocerca volvulus Huntingtin homolog 0.013 0.0857 0.135
Brugia malayi Patched related family protein 10 0.0013 0.0009 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0047 0.0254 0.2007
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0022 0.0085
Onchocerca volvulus 0.0013 0.0009 0.0013
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0038 0.0187 0.1481
Schistosoma mansoni hypothetical protein 0.0558 0.3962 0.3962
Brugia malayi hypothetical protein 0.0041 0.0212 0.028
Echinococcus multilocularis expressed conserved protein 0.0131 0.0863 0.0863
Entamoeba histolytica hypothetical protein 0.0037 0.0184 0.0712
Echinococcus granulosus cysteine protease atg4b 0.012 0.0784 0.0784
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0041 0.0212 0.082
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0042 0.0218 0.2569
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0015 0.0022 0.0085
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.014 0.014
Trypanosoma brucei heat shock protein, putative 0.0044 0.0237 0.3029
Schistosoma mansoni heat shock protein 0.0044 0.0237 0.0237
Brugia malayi beta-NAC-like protein 0.0037 0.0184 0.0243
Loa Loa (eye worm) hypothetical protein 0.0037 0.0187 0.0247
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0056 0.0074
Trypanosoma brucei SUMO1/Ulp2, putative 0.0038 0.0187 0.2389
Loa Loa (eye worm) hypothetical protein 0.0037 0.0187 0.0247
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0031
Echinococcus multilocularis sentrin specific protease 1 0.0038 0.0187 0.0187
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0022 0.0029
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Loa Loa (eye worm) patched family protein 0.0013 0.0009 0.0011
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0187 0.0725
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0187 0.0725
Schistosoma mansoni hypothetical protein 0.0055 0.0316 0.0316
Echinococcus multilocularis musashi 0.0032 0.0148 0.0148
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0339 0.1312
Onchocerca volvulus 0.0013 0.0009 0.0013
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0148 0.0195
Onchocerca volvulus 0.0041 0.0212 0.0334
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0046 0.0246 0.0246
Brugia malayi heat shock protein 90 0.0044 0.0237 0.0314
Treponema pallidum heat shock protein 90 0.0042 0.0218 0.1103
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0056 0.0216
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Brugia malayi hypothetical protein 0.0013 0.0009 0.0011
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.012 0.0784 0.3032
Echinococcus granulosus muscleblind protein 0.0158 0.1059 0.1059
Schistosoma mansoni autophagin-1 (C54 family) 0.012 0.0784 0.0784
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Echinococcus granulosus sentrin specific protease 7 0.0168 0.1136 0.1136
Loa Loa (eye worm) hypothetical protein 0.0037 0.0187 0.0247
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Schistosoma mansoni heat shock protein 0.0044 0.0237 0.0237
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0212 0.028
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0368 0.2584 1
Brugia malayi hypothetical protein 0.0041 0.0212 0.028
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0041 0.0212 0.0212
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0339 0.0339
Plasmodium vivax heat shock protein 90, putative 0.003 0.0129 0.1136
Onchocerca volvulus 0.0041 0.0212 0.0334
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0022 0.0279
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0041 0.0212 0.0212
Onchocerca volvulus 0.0232 0.1597 0.2514
Giardia lamblia Heat shock protein HSP 90-alpha 0.0038 0.0191 0.0738
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0139 0.0184
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.014 0.1111
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Echinococcus multilocularis dnaJ subfamily B 0.1389 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0184 0.0712
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0041 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0056 0.0712
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0067 0.0404 0.0404
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1395 0.1843
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Toxoplasma gondii patched family protein 0.0013 0.0009 0.0067
Onchocerca volvulus 0.0041 0.0212 0.0334
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.1972 0.7629
Toxoplasma gondii heat shock protein 75, putative 0.003 0.0129 0.1022
Toxoplasma gondii NAC domain-containing protein 0.0037 0.0184 0.1455
Entamoeba histolytica peptidase, C54 family 0.0047 0.0254 0.0982
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Brugia malayi hypothetical protein 0.0013 0.0009 0.0011
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.012 0.0784 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0368 0.2584 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0041 0.0212 0.082
Echinococcus granulosus lamin 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0029
Loa Loa (eye worm) hypothetical protein 0.005 0.0279 0.0369
Onchocerca volvulus 0.0041 0.0212 0.0334
Loa Loa (eye worm) hypothetical protein 0.0112 0.0726 0.0959
Onchocerca volvulus 0.0041 0.0212 0.0334
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0029
Entamoeba histolytica hypothetical protein 0.0114 0.0744 0.288
Brugia malayi protein C24B5.3 0.0013 0.0009 0.0011
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0339 0.4327
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0184 0.2347
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0279 0.108
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0022 0.0085
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0046 0.0246 0.0246
Schistosoma mansoni hypothetical protein 0.0067 0.0404 0.0404
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0041 0.0212 0.0212
Toxoplasma gondii patched family protein 0.0013 0.0009 0.0067
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Brugia malayi MAP kinase sur-1 0.0058 0.0339 0.0448
Loa Loa (eye worm) hypothetical protein 0.0887 0.6353 0.8393
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0184 0.0712
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0022 0.0085
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0046 0.0246 0.0325
Brugia malayi Patched family protein 0.0013 0.0009 0.0011
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Trichomonas vaginalis helicase, putative 0.0022 0.0075 0.0292
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0368 0.2584 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0292
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0187 0.0247
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0279 0.108
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0089 0.0564 0.0745
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Onchocerca volvulus 0.0041 0.0212 0.0334
Schistosoma mansoni hypothetical protein 0.0088 0.0553 0.0553
Trypanosoma cruzi heat shock protein 85, putative 0.0038 0.0191 0.2435
Loa Loa (eye worm) hypothetical protein 0.012 0.0784 0.1035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Echinococcus multilocularis Niemann Pick C1 protein 0.0213 0.1458 0.1458
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0011
Onchocerca volvulus 0.0098 0.0623 0.0981
Leishmania major heat shock protein 83-1 0.0044 0.0237 0.2829
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0022 0.0085
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0339 0.1312
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0279 0.3377
Toxoplasma gondii hypothetical protein 0.0013 0.0009 0.0067
Plasmodium falciparum lipid/sterol:H+ symporter 0.0013 0.0009 0.0075
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1597 0.618
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0212 0.028
Plasmodium vivax heat shock protein, putative 0.0168 0.1137 1
Echinococcus granulosus geminin 0.0558 0.3962 0.3962
Onchocerca volvulus Phospholipase A2 homolog 0.0887 0.6353 1
Echinococcus multilocularis muscleblind protein 1 0.0158 0.1059 0.1059
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0292
Echinococcus granulosus intermediate filament protein 0.0032 0.0148 0.0148
Echinococcus granulosus expressed conserved protein 0.02 0.1365 0.1365
Loa Loa (eye worm) Ulp1 protease 0.0089 0.0564 0.0745
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0184 0.2347
Loa Loa (eye worm) oxidoreductase 0.0015 0.0022 0.0029
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.012 0.0784 0.0784
Onchocerca volvulus Protein patched homolog 0.0013 0.0009 0.0013
Schistosoma mansoni protein tyrosine phosphatase 0.0041 0.0212 0.0212
Trypanosoma brucei heat shock protein, putative 0.0044 0.0237 0.3029
Loa Loa (eye worm) hypothetical protein 0.0073 0.0448 0.0592
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0279 0.3035
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0237 0.0918
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0339 0.0339
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.028
Schistosoma mansoni hypothetical protein 0.0114 0.0744 0.0744
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.1972 0.7629
Onchocerca volvulus Huntingtin homolog 0.013 0.0857 0.135
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0218 0.0842

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 280 uM Inhibition of APN from pig kidney microsomes by spectrophotometry ChEMBL. 19969464
IC50 (binding) = 428.3 uM Inhibition of MMP2 by spectrophotometry ChEMBL. 19969464

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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