Detailed information for compound 1157715

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 348.437 | Formula: C19H28N2O4
  • H donors: 1 H acceptors: 1 LogP: 1.32 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCN1CCC2(CC1)CC(NC(=O)COC)c1c(O2)cccc1
  • InChi: 1S/C19H28N2O4/c1-23-12-11-21-9-7-19(8-10-21)13-16(20-18(22)14-24-2)15-5-3-4-6-17(15)25-19/h3-6,16H,7-14H2,1-2H3,(H,20,22)
  • InChiKey: GSRXQHNZBHYHKZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0017 0.0002 0.0002
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0021 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0024 0.005 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni alpha-13-mannosyl-glycoprotein beta-1 2-n-acetylglucosaminyltransferase 0.0107 0.0652 0.0652
Mycobacterium ulcerans methionyl-tRNA synthetase 0.0062 0.0326 0.7322
Leishmania major glycerol uptake protein, putative 0.0021 0.0032 0.0698
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0017 0.0002 0.0002
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0015 0.0335
Schistosoma mansoni methionine-tRNA synthetase 0.0024 0.005 0.005
Onchocerca volvulus 0.0494 0.3446 1
Brugia malayi diacylglycerol acyltransferase 0.0125 0.0783 0.0783
Brugia malayi Dopamine receptor protein 2 0.0017 0.0002 0.0002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0002 0.0002
Echinococcus multilocularis g-protein coupled receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0078 0.0446 0.0445
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0125 0.0783 0.0783
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 0.1402 1 1
Mycobacterium leprae Probable methionyl-tRNA synthase MetS 0.0062 0.0326 0.378
Onchocerca volvulus 0.0246 0.1657 0.4805
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0017 0.0002 0.0002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0119 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0088 0.048
Echinococcus granulosus fetal alzheimer antigen falz 0.0048 0.0225 0.0225
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0243 0.1636 0.1636
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0119 0.0119
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1165 0.6337
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0132 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0665 0.362
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0021 0.0032 0.0032
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.0024 0.005 0.005
Trichomonas vaginalis methionine-tRNA synthetase, putative 0.0062 0.0326 0.1774
Brugia malayi MBOAT family protein 0.0021 0.0032 0.0032
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0017 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni opsin-like receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0015 0.0458
Echinococcus multilocularis alpha 1,3 mannosyl glycoprotein 0.0107 0.0652 0.0652
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0017 0.0002 0.0002
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0125 0.0783 0.0783
Loa Loa (eye worm) hypothetical protein 0.0078 0.0445 0.0444
Echinococcus granulosus g protein coupled receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0092
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0445 0.2423
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.0636 0.0636
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0445 0.5496
Schistosoma mansoni neuropeptide f receptor 76f 0.0017 0.0002 0.0002
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0063 0.1391
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1165 0.6337
Schistosoma mansoni bromodomain containing protein 0.0131 0.0826 0.0826
Brugia malayi Heterochromatin protein 1 0.0073 0.0405 0.0405
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0021 0.0032 0.0032
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0002 0.0002
Brugia malayi diacylglycerol acyltransferase family protein 0.008 0.0456 0.0456
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0017 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0108 0.0108
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.041 0.041
Schistosoma mansoni biogenic amine receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0665 0.362
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0048 0.0225 0.0225
Schistosoma mansoni neuropeptide receptor 0.0017 0.0002 0.0002
Echinococcus granulosus dro:myosuppressin receptor 0.0017 0.0002 0.0002
Mycobacterium ulcerans leucyl-tRNA synthetase 0.0024 0.005 0.1129
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0021 0.0032 0.0432
Echinococcus granulosus neuropeptide s receptor 0.05 0.349 0.349
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0405 0.0403
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0066 0.036 0.036
Brugia malayi hypothetical protein 0.0123 0.0767 0.0767
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0111 0.0109
Brugia malayi MBOAT family protein 0.0021 0.0032 0.0032
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0021 0.0032 0.0032
Schistosoma mansoni diacylglycerol O-acyltransferase 0.0018 0.0008 0.0008
Brugia malayi Zinc finger, C2H2 type family protein 0.0307 0.2099 0.2099
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0073 0.0407 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0407 0.0407
Schistosoma mansoni leucyl-tRNA synthetase 0.0024 0.005 0.005
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Trypanosoma cruzi GUP1, putative 0.0021 0.0032 0.0698
Trypanosoma cruzi glycerol uptake protein, putative 0.0021 0.0032 0.0698
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0017 0.0002 0.0002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0407 0.0407
Loa Loa (eye worm) hypothetical protein 0.0107 0.0652 0.065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.036 0.036
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0018 0.0008 0.0168
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0002 0.0002
Echinococcus granulosus alpha 13 mannosyl glycoprotein 0.0107 0.0652 0.0652
Brugia malayi protein ZK524.3 0.0024 0.005 0.005
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0226 0.496
Echinococcus granulosus G protein coupled receptor 139 0.0017 0.0002 0.0002
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0184 0.0183
Brugia malayi methionyl-tRNA synthetase 0.0062 0.0326 0.0326
Schistosoma mansoni hypothetical protein 0.0073 0.0407 0.0407
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0015 0.0327
Echinococcus multilocularis G protein coupled receptor 139 0.0017 0.0002 0.0002
Echinococcus multilocularis zinc finger transcription factor gli2 0.0307 0.2099 0.2099
Loa Loa (eye worm) hhat protein 0.0021 0.0032 0.003
Schistosoma mansoni chromobox protein 0.0073 0.0405 0.0405
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0123 0.0767 0.0766
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0078 0.0445 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0197 0.0566
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0002 0.0002
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0002 0.0002
Trypanosoma brucei trypanothione reductase 0.0048 0.0226 0.496
Leishmania major glycerol uptake protein, putative 0.0021 0.0032 0.0698
Brugia malayi G protein-coupled receptor F59B2.13 0.0017 0.0002 0.0002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0017 0.0002 0.0002
Echinococcus multilocularis chromobox protein 1 0.0073 0.0405 0.0405
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0031 0.0106 0.0106
Plasmodium vivax hypothetical protein, conserved 0.0078 0.0445 0.5683
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0665 0.362
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0002 0.0002
Plasmodium falciparum methionine--tRNA ligase, putative 0.0024 0.005 0.0641
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0243 0.1636 0.1636
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0132 0.0132
Mycobacterium ulcerans hypothetical protein 0.0018 0.0008 0.0172
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0063 0.081
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0072 0.0397 0.0397
Echinococcus granulosus GPCR family 2 0.0033 0.0119 0.0119
Echinococcus granulosus L aminoadipate semialdehyde 0.009 0.0532 0.0532
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0017 0.0002 0.0002
Entamoeba histolytica hypothetical protein, conserved 0.0021 0.0032 0.0432
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0174 0.0948
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0445 0.0445
Echinococcus multilocularis somatostatin receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0048 0.0225 0.0225
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.036 0.036
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0445 0.2423
Schistosoma mansoni cpg binding protein 0.0037 0.0146 0.0146
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.009 0.0532 0.0531
Trypanosoma cruzi glycerol uptake protein, putative 0.0021 0.0032 0.0698
Schistosoma mansoni growth hormone secretagogue receptor 0.0017 0.0002 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Leishmania major methionyl-tRNA synthetase, putative 0.0062 0.0326 0.7146
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0078 0.0445 0.0444
Toxoplasma gondii methionyl-tRNA synthetase 0.0062 0.0326 0.4161
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1165 0.6337
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0445 0.2423
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0405 0.2203
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0021 0.0032 0.0032
Onchocerca volvulus 0.0078 0.0445 0.1288
Brugia malayi RE15519p 0.0017 0.0002 0.0002
Brugia malayi beta-lactamase family protein 0.0078 0.0445 0.0445
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.0445 0.0444
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0108 0.1381
Leishmania major diacylglycerol acyltransferase, putative 0.0018 0.0008 0.0168
Echinococcus granulosus hypothetical protein 0.0017 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.1838 1
Brugia malayi GNT-I family protein 0.0107 0.0652 0.0652
Echinococcus granulosus histone lysine methyltransferase setb 0.0066 0.036 0.036
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0015 0.0015
Chlamydia trachomatis methionine--tRNA ligase 0.0024 0.005 0.7918
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0015 0.0081
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.0445 0.0445
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0015 0.0043
Loa Loa (eye worm) hypothetical protein 0.0105 0.0636 0.0634
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0021 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0032 0.003
Trypanosoma cruzi GUP1, putative 0.0021 0.0032 0.0698
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0021 0.0032 0.0032
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0063 0.1391
Brugia malayi putative neuropeptide receptor NPR1 0.0017 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0063 0.1947
Echinococcus multilocularis methionine tRNA synthetase 0.0062 0.0326 0.0326
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0015 0.0327
Treponema pallidum leucyl-tRNA synthetase 0.0024 0.005 0.7918
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0197 0.1069
Loa Loa (eye worm) hypothetical protein 0.0072 0.0397 0.0395
Echinococcus granulosus 7TM GPCR rhodopsin 0.0017 0.0002 0.0002
Schistosoma mansoni chromobox protein 0.0073 0.0405 0.0405
Treponema pallidum methionyl-tRNA synthetase 0.0024 0.005 0.7918
Brugia malayi Glycosylation related protein 12, isoform 0.0036 0.0142 0.0142
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0021 0.0032 0.0032
Trypanosoma brucei diacylglycerol acyltransferase, putative 0.008 0.0456 1
Brugia malayi Dopamine receptor protein 1 0.0017 0.0002 0.0002
Brugia malayi Melatonin receptor type 1A 0.0017 0.0002 0.0002
Leishmania major leucyl-tRNA synthetase, putative 0.0024 0.005 0.1102
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0015 0.0013
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0271 0.1838 0.1838
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.0445 0.1275
Mycobacterium tuberculosis Conserved protein 0.0078 0.0445 0.1275
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0017 0.0002 0.0002
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.0073 0.0407 0.0407
Loa Loa (eye worm) hypothetical protein 0.0024 0.005 0.0049
Leishmania major hypothetical protein, conserved 0.0078 0.0445 0.976
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0359 0.1952
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0015 0.0081
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0197 0.1069
Echinococcus granulosus o acyltransferase membrane bound domain 0.0021 0.0032 0.0032
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0002 0.0002
Brugia malayi Tachykinin-like peptides receptor 99D 0.0017 0.0002 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0017 0.0092
Echinococcus granulosus zinc finger protein 0.0042 0.0182 0.0182
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0018 0.0007 0.0007
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0021 0.0032 0.0432
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0015 0.019
Echinococcus granulosus cpg binding protein 0.0037 0.0146 0.0146
Brugia malayi neuropeptide F receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis transmembrane protein nessy, putative 0.0021 0.0032 0.0173
Onchocerca volvulus 0.0031 0.0105 0.0301
Echinococcus multilocularis serotonin receptor 0.0017 0.0002 0.0002
Echinococcus granulosus neuropeptide receptor 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0042 0.0184 0.0184
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1165 0.6337
Toxoplasma gondii tRNA ligases class I (M) protein 0.0024 0.005 0.0641
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0002 0.0002
Trypanosoma cruzi glycerol uptake protein, putative 0.0021 0.0032 0.0698
Schistosoma mansoni zinc finger protein 0.0021 0.0032 0.0032
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0226 0.2888
Trypanosoma cruzi ISWI complex protein 0.0031 0.0106 0.2317
Schistosoma mansoni cpg binding protein 0.0031 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0665 0.362
Schistosoma mansoni zinc finger protein 0.0031 0.0106 0.0106
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0002 0.0002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0445 0.0445
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.008 0.0456 1
Leishmania major trypanothione reductase 0.0048 0.0226 0.496
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.0636 0.0634
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0243 0.1636 0.1636
Echinococcus granulosus g-protein coupled receptor 0.0017 0.0002 0.0002
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0758 0.2171
Trypanosoma brucei glycerol uptake protein, putative 0.0021 0.0032 0.0698
Loa Loa (eye worm) beta-lactamase 0.0078 0.0445 0.0444
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1165 0.6337
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0243 0.1636 0.1636
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0119 0.0119
Echinococcus multilocularis G-protein coupled receptor, putative 0.0017 0.0002 0.0002
Brugia malayi follicle stimulating hormone receptor 0.0017 0.0002 0.0002
Mycobacterium ulcerans lipase LipD 0.0078 0.0445 1
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0008
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0132 0.0132
Schistosoma mansoni neuropeptide receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) MBOAT family protein 0.0021 0.0032 0.003
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0124 0.0774 0.0774
Wolbachia endosymbiont of Brugia malayi methionyl-tRNA synthetase 0.0062 0.0326 1
Schistosoma mansoni cpg binding protein 0.0037 0.0146 0.0146
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0021 0.0032 0.0032
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0018 0.0008 0.0168
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.0445 0.1275
Echinococcus granulosus somatostatin receptor 0.0017 0.0002 0.0002
Schistosoma mansoni diacylglycerol O-acyltransferase 0.0018 0.0008 0.0008
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0063 0.1426
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.1234 0.6713
Brugia malayi Bromodomain containing protein 0.0155 0.0999 0.0999
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0445 0.976
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0132 0.0132
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0125 0.0783 1
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0018 0.0008 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Toxoplasma gondii diacylglycerol acyltransferase 0.0018 0.0008 0.0098
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.0445 0.1275
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0119 0.0119
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0194 0.0194
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.1838 1
Schistosoma mansoni zinc finger protein 0.0042 0.0182 0.0182
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.0445 0.1275
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.067 0.1919
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0021 0.0032 0.0432
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0243 0.1636 0.1636
Schistosoma mansoni opsin-like receptor 0.0017 0.0002 0.0002
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0063 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0032 0.003
Loa Loa (eye worm) tyrosyl-tRNA synthetase 0.0038 0.0156 0.0154
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.041 0.041
Mycobacterium ulcerans beta-lactamase 0.0078 0.0445 1
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0063 1
Schistosoma mansoni sterol O-acyltransferase 1 0.0021 0.0032 0.0032
Trypanosoma brucei methionyl-tRNA synthetase, putative 0.0062 0.0326 0.7146
Schistosoma mansoni biogenic amine receptor 0.0017 0.0002 0.0002
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.009 0.0532 0.0532
Echinococcus granulosus sex peptide receptor 0.0017 0.0002 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0002 0.0002
Brugia malayi neuropeptide F receptor 0.0017 0.0002 0.0002
Mycobacterium leprae Probable lipase LipE 0.0078 0.0445 0.5496
Echinococcus granulosus methionine tRNA synthetase 0.0062 0.0326 0.0326
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0002 0.0002
Toxoplasma gondii hypothetical protein 0.0042 0.0186 0.238
Brugia malayi putative neuropeptide receptor 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0346 0.238 0.238
Trypanosoma brucei diacylglycerol acyltransferase, putative 0.0018 0.0008 0.0168
Brugia malayi beta-lactamase 0.0078 0.0445 0.0445
Schistosoma mansoni hypothetical protein 0.0033 0.0119 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Plasmodium falciparum thioredoxin reductase 0.0048 0.0226 0.2888
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0032 0.0173
Trypanosoma brucei ISWI complex protein 0.0031 0.0106 0.2317
Brugia malayi MBOAT family protein 0.0021 0.0032 0.0032
Brugia malayi Dopamine receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis neuropeptide FF receptor 2 0.0017 0.0002 0.0002
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0015 0.2351
Echinococcus granulosus o acyltransferase membrane bound domain 0.0021 0.0032 0.0032
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis esterase, putative 0.0078 0.0445 0.2423
Echinococcus multilocularis leucyl tRNA synthetase 0.0024 0.005 0.005
Entamoeba histolytica vacuolar protein sorting 26 0.0021 0.0032 0.0432
Loa Loa (eye worm) pax transcription factor protein 2 0.0494 0.3446 0.3445
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0017 0.0002 0.0002
Loa Loa (eye worm) CHromoDomain protein family member 0.0018 0.0007 0.0005
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0021 0.0032 0.0032
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0125 0.0783 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0017 0.0002 0.0002
Brugia malayi sulfakinin receptor protein 0.0017 0.0002 0.0002
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0017 0.0002 0.0002
Trichomonas vaginalis porcupine, putative 0.0021 0.0032 0.0173
Schistosoma mansoni neuropeptide receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis sterol O acyltransferase 1 0.0021 0.0032 0.0032
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.1442 0.144
Giardia lamblia Leucyl-tRNA synthetase 0.0024 0.005 0.1542
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0015 0.0327
Trichomonas vaginalis set domain proteins, putative 0.0246 0.1657 0.9014
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0017 0.0002 0.0002
Brugia malayi G-protein coupled receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) methionyl-tRNA synthetase 0.0062 0.0326 0.0324
Schistosoma mansoni opsin-like receptor 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.0445 0.1275
Loa Loa (eye worm) hypothetical protein 0.0083 0.0481 0.0479
Mycobacterium tuberculosis Probable reductase 0.0109 0.067 0.1919
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.067 0.1919
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0021 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0117
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0119 0.0119
Brugia malayi methionyl-tRNA synthetase 0.0024 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0032 0.003
Leishmania major hypothetical protein, conserved 0.0021 0.0032 0.0698
Brugia malayi GnHR receptor homolog 0.0017 0.0002 0.0002
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0021 0.0032 0.0032
Plasmodium vivax SET domain protein, putative 0.0032 0.0108 0.1381
Echinococcus granulosus neuropeptide receptor 0.0017 0.0002 0.0002
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0017 0.0002 0.0002
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0226 0.0226
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.035 0.4468
Schistosoma mansoni histamine h1 receptor 0.0017 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0002 0.0002
Schistosoma mansoni adenoreceptor 0.0017 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0032 0.0173
Plasmodium vivax hypothetical protein, conserved 0.0024 0.005 0.0641
Echinococcus granulosus alpha 1A adrenergic receptor 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0032 0.0111 0.0316
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0024 0.005 0.0901
Loa Loa (eye worm) hypothetical protein 0.0104 0.0632 0.063
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0002 0.0002
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.0445 0.0445
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.1234 0.6713
Loa Loa (eye worm) hypothetical protein 0.0041 0.0174 0.0173
Leishmania major hypothetical protein, unknown function,protein, unknown function 0.0018 0.0008 0.0168
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.0445 0.3089 0.3089
Echinococcus multilocularis orexin receptor type 2 0.0017 0.0002 0.0002
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0141 0.0139
Echinococcus multilocularis geminin 0.0346 0.238 0.238
Echinococcus multilocularis L aminoadipate semialdehyde 0.009 0.0532 0.0532
Brugia malayi glutathione reductase 0.0048 0.0226 0.0226
Echinococcus granulosus dnaJ subfamily B 0.0445 0.3089 0.3089
Echinococcus granulosus chromobox protein 1 0.0073 0.0405 0.0405
Brugia malayi PHD-finger family protein 0.0053 0.026 0.026
Loa Loa (eye worm) hhat protein 0.0021 0.0032 0.003
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0105 0.0104
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0002 0.0002
Schistosoma mansoni ap endonuclease 0.0019 0.0015 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0092
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 0.1402 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1165 0.6337
Trypanosoma brucei glycerol uptake protein, putative 0.0021 0.0032 0.0698
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0015 0.0015
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0002 0.0002
Onchocerca volvulus Huntingtin homolog 0.0123 0.0767 0.2223
Schistosoma mansoni myosin xvIII 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0033 0.0119 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0174 0.0948
Leishmania major glycerol uptake protein, putative 0.0021 0.0032 0.0698
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0445 0.2423
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0243 0.1636 0.1636
Onchocerca volvulus 0.009 0.0532 0.1541
Loa Loa (eye worm) hypothetical protein 0.0024 0.005 0.0049
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Toxoplasma gondii ABC1 family protein 0.0078 0.0445 0.5683
Entamoeba histolytica hypothetical protein 0.0073 0.0407 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0108 0.0108
Mycobacterium tuberculosis Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) 0.0062 0.0326 0.0934
Leishmania major hypothetical protein, conserved 0.0031 0.0106 0.2317
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0243 0.1636 0.1636
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0226 0.0225
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.067 0.1919
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.0445 0.1275
Leishmania major diacylglycerol acyltransferase, putative 0.0018 0.0008 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0665 0.362
Schistosoma mansoni hypothetical protein 0.0346 0.238 0.238
Echinococcus granulosus neuropeptide receptor A26 0.05 0.349 0.349
Loa Loa (eye worm) hypothetical protein 0.0107 0.0652 0.065
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.0445 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0063 0.081
Plasmodium vivax methionine--tRNA ligase, putative 0.0062 0.0326 0.4161
Echinococcus multilocularis zinc finger protein 0.0042 0.0182 0.0182
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0125 0.0783 0.0782
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0243 0.1636 0.1636
Onchocerca volvulus Huntingtin homolog 0.0123 0.0767 0.2223
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0407 0.0407
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0017 0.0002 0.0002
Leishmania major diacylglycerol acyltransferase, putative 0.008 0.0456 1
Onchocerca volvulus 0.0044 0.0194 0.0559
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0445 0.976
Echinococcus granulosus fmrfamide receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) MBOAT family protein 0.0021 0.0032 0.003
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0063 0.0182
Schistosoma mansoni alpha-1 adrenergic receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.1838 1
Brugia malayi ORL1-like opioid receptor 0.0017 0.0002 0.0002
Giardia lamblia Methionyl-tRNA synthetase 0.0062 0.0326 1
Echinococcus multilocularis neuropeptide s receptor 0.05 0.349 0.349
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0002 0.0002
Toxoplasma gondii Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 0.0036 0.0142 0.181
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0226 0.0226
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0119 0.0117
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0397 0.0397
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0445 0.2423
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0018 0.0008 0.0168
Plasmodium falciparum methionine--tRNA ligase 0.0062 0.0326 0.4161
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Brugia malayi Thioredoxin reductase 0.0048 0.0226 0.0226
Echinococcus granulosus o acyltransferase membrane bound domain 0.0021 0.0032 0.0032
Mycobacterium tuberculosis Conserved protein 0.0078 0.0445 0.1275
Echinococcus granulosus sterol O acyltransferase 1 0.0021 0.0032 0.0032
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0063 0.081
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0174 0.0501
Schistosoma mansoni hypothetical protein 0.0033 0.0119 0.0119
Loa Loa (eye worm) diacylglycerol acyltransferase 0.008 0.0456 0.0455
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.1838 1
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0002 0.0002
Brugia malayi Serotonin receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1165 0.6337
Loa Loa (eye worm) MBOAT family protein 0.0021 0.0032 0.003
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0002 0.0002
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.1402 1 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0017 0.0002 0.0002
Leishmania major glycerol uptake protein, putative 0.0021 0.0032 0.0698
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0092
Echinococcus multilocularis chromobox protein 1 0.0073 0.0405 0.0405
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0758 0.2171
Mycobacterium tuberculosis Conserved protein 0.0078 0.0445 0.1275
Leishmania major glycerol uptake protein, putative 0.0021 0.0032 0.0698
Echinococcus granulosus peptide allatostatin:somatostatin 0.0017 0.0002 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0021 0.0032 0.0032
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0021 0.0032 0.003
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0002 0.0002
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0063 0.1426
Loa Loa (eye worm) hypothetical protein 0.0078 0.0445 0.0444
Brugia malayi Bromodomain containing protein 0.0078 0.0445 0.0445
Loa Loa (eye worm) hypothetical protein 0.0145 0.0923 0.0922
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0125 0.0783 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Echinococcus granulosus neuropeptide FF receptor 2 0.0017 0.0002 0.0002
Mycobacterium ulcerans hypothetical protein 0.0078 0.0445 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0018 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0445 0.3089 0.3089
Loa Loa (eye worm) hypothetical protein 0.0078 0.0445 0.0444
Brugia malayi G-protein coupled receptor 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Schistosoma mansoni neuropeptide receptor 0.0017 0.0002 0.0002
Echinococcus granulosus serotonin receptor 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0038 0.0156 0.0447
Mycobacterium tuberculosis Possible penicillin-binding protein 0.05 0.3491 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0017 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0665 0.362
Brugia malayi CHD4 protein 0.0018 0.0007 0.0007
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0017 0.0002 0.0002
Brugia malayi Hhat protein 0.0021 0.0032 0.0032
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0021 0.0032 0.0032
Plasmodium vivax glutathione reductase, putative 0.0048 0.0226 0.2888
Loa Loa (eye worm) hypothetical protein 0.0036 0.0142 0.014
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0002 0.0002
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.009 0.0532 0.0532
Brugia malayi Serotonin receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0665 0.362
Loa Loa (eye worm) hypothetical protein 0.0078 0.0445 0.0444
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0017 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0025 0.0063 0.1238
Brugia malayi beta-lactamase family protein 0.0078 0.0445 0.0445
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.0024 0.005 0.005
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.008 0.0456 1
Echinococcus granulosus allatostatin A receptor 0.0017 0.0002 0.0002
Toxoplasma gondii thioredoxin reductase 0.0048 0.0226 0.2888
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0226 0.0648
Echinococcus granulosus chromobox protein 1 0.0073 0.0405 0.0405
Trypanosoma cruzi ISWI complex protein 0.0031 0.0106 0.2317
Loa Loa (eye worm) hypothetical protein 0.0078 0.0445 0.0444
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0073 0.0407 1
Schistosoma mansoni ap endonuclease 0.0019 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0073 0.0407 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.067 0.1919
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0445 0.976
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0095 0.0095
Brugia malayi chromobox protein homolog 3 0.0041 0.0174 0.0174
Toxoplasma gondii dgat2l1-prov protein 0.008 0.0456 0.5823
Plasmodium vivax methionine--tRNA ligase, putative 0.0024 0.005 0.0641
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0032 0.0173
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0366 0.0366
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.008 0.0456 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0665 0.362
Brugia malayi Pre-SET motif family protein 0.0216 0.1442 0.1442
Loa Loa (eye worm) zinc finger protein 0.0307 0.2099 0.2097
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.067 0.1919
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0088 0.048
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0758 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0758 0.2171
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0021 0.0032 0.0432
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0119 0.0119
Brugia malayi Pax transcription factor protein 2 0.0494 0.3446 0.3446
Loa Loa (eye worm) hypothetical protein 0.0021 0.0032 0.003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.067 0.8731
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0092
Onchocerca volvulus 0.0078 0.0445 0.1288
Toxoplasma gondii hypothetical protein 0.0021 0.0032 0.0407
Trypanosoma cruzi methionyl-tRNA synthetase, putative 0.0062 0.0326 0.7146
Chlamydia trachomatis leucine--tRNA ligase 0.0024 0.005 0.7918
Echinococcus multilocularis sex peptide receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0066 0.036 0.0358
Loa Loa (eye worm) glutathione reductase 0.0048 0.0226 0.0225
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.0445 0.0445
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0015 0.0327
Echinococcus granulosus g protein coupled receptor 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.1838 1
Echinococcus multilocularis cpg binding protein 0.0037 0.0146 0.0146
Brugia malayi MBOAT family protein 0.0021 0.0032 0.0032
Onchocerca volvulus Glucosylceramidase homolog 0.0178 0.1165 0.3377
Treponema pallidum alginate O-acetylation protein (algI) 0.0021 0.0032 0.5018
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0002 0.0002
Echinococcus granulosus orexin receptor type 2 0.0017 0.0002 0.0002
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0078 0.0445 0.1288
Echinococcus granulosus g protein coupled receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.1838 1
Loa Loa (eye worm) hypothetical protein 0.0123 0.0767 0.0766
Echinococcus multilocularis GPCR, family 2 0.0033 0.0119 0.0119
Brugia malayi Pre-SET motif family protein 0.0032 0.0108 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0002 0.0002
Schistosoma mansoni methionine-tRNA synthetase 0.0062 0.0326 0.0326
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0017 0.0002 0.0002
Echinococcus multilocularis serotonin receptor 0.0017 0.0002 0.0002
Echinococcus granulosus geminin 0.0346 0.238 0.238
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0063 0.081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0092
Schistosoma mansoni biogenic amine receptor 0.0017 0.0002 0.0002
Brugia malayi G protein-coupled receptor 0.0017 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Brugia malayi MBOAT family protein 0.0021 0.0032 0.0032
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0021 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0033 0.0119 0.0119
Echinococcus granulosus zinc finger transcription factor gli2 0.0307 0.2099 0.2099
Loa Loa (eye worm) hypothetical protein 0.0089 0.0522 0.052
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0124 0.0774 0.0774
Toxoplasma gondii mono- or diacylglycerol acyltransferase 0.0018 0.0008 0.0098
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0271 0.1838 0.1837
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0405 0.2203
Brugia malayi AKH receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0021 0.0032 0.0032
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0125 0.0783 1
Echinococcus multilocularis allatostatin A receptor 0.0017 0.0002 0.0002
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0021 0.0032 0.0032
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.0636 0.0636
Brugia malayi CXXC zinc finger family protein 0.0031 0.0105 0.0105
Onchocerca volvulus 0.0021 0.0032 0.0088
Onchocerca volvulus 0.008 0.0456 0.132
Wolbachia endosymbiont of Brugia malayi leucyl-tRNA synthetase 0.0024 0.005 0.1542
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0125 0.0783 0.0783
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0002 0.0002
Brugia malayi larval opioid receptor 0.0017 0.0002 0.0002
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0015 0.019
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0243 0.1636 0.1635
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0015 0.0458
Toxoplasma gondii exonuclease III APE 0.0019 0.0015 0.019
Echinococcus granulosus 7tm_1 domain containing protein 0.0017 0.0002 0.0002
Echinococcus multilocularis neuropeptide receptor A26 0.05 0.349 0.349
Echinococcus multilocularis dro:myosuppressin receptor 0.0017 0.0002 0.0002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0018 0.0007 0.0007
Plasmodium falciparum glutathione reductase 0.0048 0.0226 0.2888
Echinococcus granulosus alpha 16 mannosyl glycoprotein 0.1402 1 1
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.0445 0.1275

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

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