Detailed information for compound 1216983

Basic information

Technical information
  • TDR Targets ID: 1216983
  • Name: 5-methyl-N-(6-methylsulfonyl-1,3-benzothiazol -2-yl)furan-2-carboxamide
  • MW: 336.386 | Formula: C14H12N2O4S2
  • H donors: 1 H acceptors: 4 LogP: 2.58 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(o1)C(=O)Nc1nc2c(s1)cc(cc2)S(=O)(=O)C
  • InChi: 1S/C14H12N2O4S2/c1-8-3-6-11(20-8)13(17)16-14-15-10-5-4-9(22(2,18)19)7-12(10)21-14/h3-7H,1-2H3,(H,15,16,17)
  • InChiKey: NITKLGPCYGJQBY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-methyl-N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)-2-furancarboxamide
  • N-(6-mesyl-1,3-benzothiazol-2-yl)-5-methyl-2-furamide
  • MLS000547159
  • ZINC00483739
  • Oprea1_130501
  • AK-968/12345400
  • 5-methyl-N-[6-(methylsulfonyl)-1,3-benzothiazol-2-yl]-2-furamide
  • IVK/8113675
  • SMR000114772

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens parathyroid hormone 1 receptor Starlite/ChEMBL No references
Photuris pennsylvanica Luciferase Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4E Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Leishmania mexicana pyruvate kinase, putative Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) Starlite/ChEMBL No references
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Chlamydia trachomatis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Theileria parva pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Neospora caninum Pyruvate kinase (EC 2.7.1.40), related Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum Pyruvate kinase isozyme R, putative Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Brugia malayi Pyruvate kinase, muscle isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii pyruvate kinase PyK1 Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium knowlesi pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium yoelii pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pyruvate kinase-PB Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Cryptosporidium parvum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Plasmodium berghei pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Entamoeba histolytica pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Babesia bovis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04588 secretin receptor, putative Get druggable targets OG5_139196 All targets in OG5_139196
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K00873 pyruvate kinase [EC2.7.1.40], putative Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Pyruvate kinase, M2 isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Giardia lamblia Pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei pyruvate kinase 1 Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma congolense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Cryptosporidium hominis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium leprae Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferase   552 aa 476 aa 25.4 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) Luciferase   552 aa 512 aa 22.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Neospora caninum hypothetical protein Luciferase   552 aa 529 aa 22.5 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Echinococcus granulosus pyruvate kinase pyruvate kinase, putative 498 aa 515 aa 27.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferase   552 aa 481 aa 20.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Schistosoma mansoni long-chain-fatty-acid--CoA ligase Luciferase   552 aa 526 aa 22.2 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferase   552 aa 510 aa 23.1 %
Leishmania mexicana long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty acid thiokinase (long chain), putative Luciferase   552 aa 472 aa 21.6 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferase   552 aa 451 aa 22.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative Luciferase   552 aa 544 aa 21.7 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferase   552 aa 470 aa 25.1 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Plasmodium vivax long-chain fatty acid CoA ligase, putative Luciferase   552 aa 453 aa 24.5 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Babesia bovis acetyl-CoA synthetase, putative Luciferase   552 aa 545 aa 21.3 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Giardia lamblia Long chain fatty acid CoA ligase 5 Luciferase   552 aa 491 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Onchocerca volvulus Luciferase   552 aa 553 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Brugia malayi AMP-binding enzyme family protein Luciferase   552 aa 492 aa 24.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferase   552 aa 481 aa 25.6 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferase   552 aa 468 aa 20.5 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferase   552 aa 481 aa 23.7 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium tuberculosis Long-chain-fatty-acid-CoA ligase FadD15 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferase   552 aa 483 aa 23.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferase   552 aa 491 aa 23.2 %
Theileria parva acetyl-coenzyme A synthetase, putative Luciferase   552 aa 580 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Inositol-1 0.0076 0.0674 0.2353
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0311 0.1042
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0542 0.0638
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0099 0.0099
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Mycobacterium tuberculosis Conserved protein 0.0108 0.1004 0.1417
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0065 0.0556 0.1934
Plasmodium falciparum mitogen-activated protein kinase 2 0.0342 0.3419 0.3724
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0064 0.0542 0.2584
Onchocerca volvulus 0.0017 0.006 0.0511
Schistosoma mansoni hypothetical protein 0.0347 0.3468 0.4084
Onchocerca volvulus 0.0108 0.1004 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.006 0.0346
Toxoplasma gondii ABC1 family protein 0.0108 0.1004 0.1644
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0082 0.0251
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.0374 0.3747
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0478 0.1658
Entamoeba histolytica hypothetical protein 0.0047 0.0374 0.3304
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0064 0.0542 0.1886
Giardia lamblia Pyruvate kinase 0.0055 0.045 0.4519
Brugia malayi Ets-domain containing protein 0.007 0.061 0.2127
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0012 0.0009 0.0000031374
Echinococcus granulosus inositol monophosphatase 1 0.0076 0.0674 0.0794
Onchocerca volvulus 0.003 0.0194 0.1855
Plasmodium falciparum acyl-CoA synthetase 0.0043 0.0328 0.0349
Toxoplasma gondii exonuclease III APE 0.0019 0.0082 0.0121
Schistosoma mansoni hypothetical protein 0.0049 0.0394 0.0464
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0314 0.1478
Mycobacterium tuberculosis Conserved protein 0.0108 0.1004 0.1417
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0374 0.2488
Brugia malayi Sugar transporter family protein 0.003 0.0194 0.0653
Schistosoma mansoni sugar transporter 0.003 0.0194 0.0228
Brugia malayi beta-lactamase family protein 0.0108 0.1004 0.3521
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0082 0.0097
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0082 0.0497
Schistosoma mansoni glucose transporter 0.003 0.0194 0.0228
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.1004 0.1182
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0108 0.1004 0.678
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0478 0.1658
Onchocerca volvulus 0.003 0.0194 0.1855
Schistosoma mansoni hypothetical protein 0.0058 0.0488 0.0574
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.1114 0.1312
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0493 0.1671
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0212 0.2072 0.2072
Echinococcus granulosus geminin 0.0347 0.3468 0.4084
Echinococcus multilocularis neuropeptide s receptor 0.0466 0.4694 0.4694
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0637 0.075
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0247 0.084
Leishmania major 4-coumarate:coa ligase-like protein 0.0057 0.0478 0.1617
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0065 0.0556 0.1887
Loa Loa (eye worm) hypothetical protein 0.0043 0.0328 0.1129
Echinococcus granulosus dnaJ subfamily B 0.0412 0.4144 0.488
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0008
Echinococcus granulosus pyruvate kinase 0.0055 0.045 0.0529
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0009 0.0000016804
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.0556 0.2649
Brugia malayi jmjC domain containing protein 0.0019 0.0082 0.0258
Echinococcus multilocularis cpg binding protein 0.0031 0.0202 0.0202
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0674 0.3224
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0564 0.1917
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0017 0.006 0.0175
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0556 0.0654
Onchocerca volvulus 0.003 0.0194 0.1855
Leishmania major hypothetical protein, conserved 0.003 0.0194 0.0637
Brugia malayi follicle stimulating hormone receptor 0.0235 0.2311 0.8143
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0404 0.1362
Leishmania major pyruvate kinase 0.0106 0.0984 0.3364
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.4144 0.4144
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0344 0.0405
Loa Loa (eye worm) beta-lactamase 0.0108 0.1004 0.3521
Brugia malayi Sugar transporter family protein 0.003 0.0194 0.0653
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.0374 0.0374
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.1315 0.4509
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0043 0.0328 0.2174
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0065 0.0556 0.0654
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0344 0.1183
Schistosoma mansoni hypothetical protein 0.0412 0.4144 0.488
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.1114 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0478 0.0667
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0017 0.006 0.0176
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0194 0.0895
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0106 0.0984 0.1388
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Plasmodium vivax acyl-CoA synthetase, putative 0.0043 0.0328 0.0349
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0064 0.0542 0.4824
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0017 0.006 0.0176
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.1004 0.4823
Loa Loa (eye worm) hypothetical protein 0.0026 0.0155 0.0518
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0564 0.2691
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Schistosoma mansoni hypothetical protein 0.0035 0.0247 0.029
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0057 0.0478 0.3193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0344 0.0405
Brugia malayi Pyruvate kinase, M2 isozyme 0.0106 0.0984 0.3448
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0108 0.1004 0.3521
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0247 0.029
Trichomonas vaginalis pyruvate kinase, putative 0.0106 0.0984 0.4724
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.1004 0.4823
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0016 0.0016
Chlamydia trachomatis pyruvate kinase 0.0106 0.0984 1
Onchocerca volvulus 0.0108 0.1004 1
Brugia malayi hypothetical protein 0.003 0.0194 0.0653
Toxoplasma gondii propionate-CoA ligase 0.0017 0.006 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.0328 0.1129
Mycobacterium ulcerans hypothetical protein 0.0108 0.1004 0.678
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0118 0.0742
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.0374 0.0441
Onchocerca volvulus 0.0029 0.0185 0.177
Brugia malayi hypothetical protein 0.0016 0.005 0.0144
Onchocerca volvulus 0.006 0.0503 0.4965
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.1004 0.4823
Giardia lamblia Threonyl-tRNA synthetase 0.0012 0.0009 0.0002
Mycobacterium leprae Probable pyruvate kinase PykA 0.0106 0.0984 0.9794
Trypanosoma brucei pyruvate kinase 1, putative 0.0106 0.0984 0.3365
Trypanosoma cruzi hexose transporter 0.0066 0.0564 0.1917
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Schistosoma mansoni hypothetical protein 0.0075 0.0664 0.0782
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.004 0.0304 0.042
Echinococcus multilocularis beta LACTamase domain containing family member 0.0108 0.1004 0.1004
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0564 0.1917
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0017 0.006 0.0511
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0016 0.0019
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0017 0.006 0.0346
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0478 0.3193
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0311 0.1042
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0212 0.2072 0.244
Echinococcus granulosus intermediate filament protein 0.0026 0.0155 0.0183
Onchocerca volvulus 0.0026 0.0155 0.147
Onchocerca volvulus 0.003 0.0194 0.1855
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.0374 0.126
Plasmodium vivax sugar transporter, putative 0.003 0.0194 0.0202
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0247 0.084
Leishmania major acetyl-CoA synthetase, putative 0.0017 0.006 0.0175
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0301 0.0415
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.0374 0.177
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0082 0.0258
Loa Loa (eye worm) hypothetical protein 0.0062 0.0532 0.1849
Entamoeba histolytica protein kinase, putative 0.0065 0.0556 0.4946
Trichomonas vaginalis glucose transporter, putative 0.003 0.0194 0.0895
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0564 0.2691
Brugia malayi Cam kinase protein 1 0.0065 0.0556 0.1934
Echinococcus granulosus beta LACTamase domain containing family member 0.0108 0.1004 0.1182
Brugia malayi jmjC domain containing protein 0.0073 0.0637 0.2221
Leishmania major myo-inositol/proton symporter (MIT) 0.003 0.0194 0.0637
Schistosoma mansoni cpg binding protein 0.0031 0.0202 0.0238
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0344 0.0405
Schistosoma mansoni lamin 0.0026 0.0155 0.0183
Onchocerca volvulus Putative transporter 0.003 0.0194 0.1855
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0017 0.006 0.046
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0556 0.0556
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.0009 0.0011
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.0651 0.2215
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.1477 0.2091
Brugia malayi jmjC domain containing protein 0.0071 0.062 0.2161
Echinococcus multilocularis pyruvate kinase 0.0106 0.0984 0.0984
Loa Loa (eye worm) pyruvate kinase 0.0106 0.0984 0.3448
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0194 0.0653
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.0036 0.0038
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trichomonas vaginalis conserved hypothetical protein 0.0212 0.2072 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0493 0.069
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.1004 0.4823
Toxoplasma gondii facilitative glucose transporter GT1 0.0212 0.2072 0.3408
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.003 0.0076
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0676 0.2361
Schistosoma mansoni intermediate filament proteins 0.0026 0.0155 0.0183
Echinococcus granulosus phd:f box containing protein 0.0019 0.0082 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0194 0.0895
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0009 0.0002
Brugia malayi hypothetical protein 0.0025 0.014 0.0462
Schistosoma mansoni gabp alpha 0.007 0.061 0.0719
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0493 0.0581
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0542 0.0638
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0311 0.1042
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Plasmodium falciparum calcium-dependent protein kinase 5 0.0065 0.0556 0.0597
Plasmodium vivax pyruvate kinase, putative 0.0106 0.0984 0.1065
Schistosoma mansoni protein kinase 0.0065 0.0556 0.0654
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0064 0.0542 0.1886
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0065 0.0556 0.0904
Echinococcus granulosus cpg binding protein 0.0031 0.0202 0.0238
Brugia malayi beta-lactamase family protein 0.0108 0.1004 0.3521
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0009 0.0009
Leishmania major acetyl-CoA synthetase, putative 0.0017 0.006 0.0175
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0082 0.012
Loa Loa (eye worm) pyruvate kinase 0.0022 0.0118 0.0384
Schistosoma mansoni patched 1 0.0051 0.0413 0.0487
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Plasmodium vivax acetyl-CoA synthetase, putative 0.0017 0.006 0.0056
Echinococcus multilocularis pyruvate kinase 0.0055 0.045 0.045
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0082 0.0097
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.8493 0.8493
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0212 0.2072 0.244
Echinococcus granulosus solute carrier family 22 0.003 0.0194 0.0228
Brugia malayi Ets-domain containing protein 0.007 0.061 0.2127
Loa Loa (eye worm) hypothetical protein 0.0065 0.0556 0.1934
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Leishmania major hypothetical protein, conserved 0.0025 0.014 0.045
Echinococcus granulosus pyruvate kinase 0.0106 0.0984 0.1158
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0676 0.2361
Brugia malayi major facilitator superfamily protein 0.003 0.0194 0.0653
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0009 0.0001
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0374 0.0441
Loa Loa (eye worm) hypothetical protein 0.011 0.1025 0.3593
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0413 0.0487
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0082 0.0082
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0235 0.2311 0.8143
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0065 0.0556 0.0597
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0017 0.006 0.0346
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.0374 0.0603
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0674 0.2296
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0247 0.0247
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0076 0.0674 0.1099
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0017 0.006 0.0072
Mycobacterium ulcerans hypothetical protein 0.0154 0.1477 1
Echinococcus multilocularis musashi 0.0026 0.0155 0.0155
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0212 0.2072 0.2072
Mycobacterium leprae Probable lipase LipE 0.0108 0.1004 1
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0257 0.0855
Toxoplasma gondii sugar transporter ST1 0.003 0.0194 0.0305
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.006 0.0072
Echinococcus granulosus lamin 0.0026 0.0155 0.0183
Brugia malayi TAR-binding protein 0.0076 0.0676 0.2361
Echinococcus granulosus neuropeptide s receptor 0.0466 0.4694 0.5527
Loa Loa (eye worm) hypothetical protein 0.0108 0.1004 0.3521
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.8493 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0503 0.1748
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.006 0.0346
Loa Loa (eye worm) hypothetical protein 0.0075 0.0664 0.2319
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0185 0.0623
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0071 0.062 0.062
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.0374 0.367
Schistosoma mansoni hypothetical protein 0.0049 0.0394 0.0464
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0194 0.0202
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.0374 0.0399
Loa Loa (eye worm) hypothetical protein 0.0043 0.0328 0.1129
Loa Loa (eye worm) hypothetical protein 0.006 0.0505 0.1755
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0194 0.0228
Echinococcus multilocularis pyruvate kinase 0.0106 0.0984 0.0984
Schistosoma mansoni jumonji domain containing protein 0.0071 0.062 0.073
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0344 0.0405
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0493 0.08
Trichomonas vaginalis antibiotic synthetase, putative 0.0017 0.006 0.0246
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.014 0.0143
Loa Loa (eye worm) hypothetical protein 0.0017 0.006 0.018
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0374 0.0441
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0017 0.006 0.0072
Brugia malayi Calcitonin receptor-like protein seb-1 0.011 0.1025 0.3593
Onchocerca volvulus 0.003 0.0194 0.1855
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0057 0.0478 0.4709
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0156 0.0518
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0017 0.006 0.018
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0194 0.0653
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0009 0.0002
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0017 0.006 0.0176
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0478 0.1658
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0108 0.1004 0.1417
Plasmodium falciparum pyruvate kinase 2 0.0055 0.045 0.0481
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0082 0.0252
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0194 0.0228
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Brugia malayi AMP-binding enzyme family protein 0.0017 0.006 0.018
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0194 0.0895
Onchocerca volvulus Pyruvate kinase homolog 0.0106 0.0984 0.9794
Onchocerca volvulus 0.003 0.0194 0.1855
Schistosoma mansoni hypothetical protein 0.0035 0.0247 0.029
Echinococcus granulosus GPCR family 2 0.0035 0.0247 0.029
Echinococcus multilocularis lamin dm0 0.0026 0.0155 0.0155
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.004 0.0304 0.042
Echinococcus multilocularis protein patched 0.0051 0.0413 0.0413
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0068 0.0592 0.083
Onchocerca volvulus 0.0017 0.006 0.0511
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0082 0.008
Plasmodium falciparum calcium-dependent protein kinase 4 0.0065 0.0556 0.0597
Brugia malayi jmjC domain containing protein 0.0019 0.0082 0.0258
Trichomonas vaginalis inositol monophosphatase, putative 0.0076 0.0674 0.3224
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0082 0.0082
Echinococcus multilocularis inositol monophosphatase 1 0.0076 0.0674 0.0674
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0009 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0676 0.0796
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Echinococcus multilocularis calcium dependent protein kinase 0.0061 0.0514 0.0514
Onchocerca volvulus 0.0026 0.0155 0.147
Mycobacterium tuberculosis Probable lipase LipD 0.0108 0.1004 0.1417
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0082 0.066
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.006 0.0346
Schistosoma mansoni topbp1 0.0012 0.0009 0.0011
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.061 0.061
Trypanosoma brucei hypothetical protein, conserved 0.0108 0.1004 0.3435
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.006 0.0346
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0564 0.1917
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0674 0.2296
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.1114 0.391
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.014 0.0451
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0082 0.0354
Onchocerca volvulus 0.003 0.0194 0.1855
Loa Loa (eye worm) hypothetical protein 0.0043 0.0328 0.1129
Trypanosoma brucei pyruvate kinase 1 0.0106 0.0984 0.3365
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0017 0.006 0.0346
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.1917
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0009 0.0000016804
Loa Loa (eye worm) hypothetical protein 0.0057 0.0478 0.1658
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.0651 0.2215
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.014 0.0216
Brugia malayi lysyl-tRNA synthetase 0.0047 0.0374 0.1292
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.0664 0.2319
Leishmania major pyruvate kinase 0.0106 0.0984 0.3364
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0082 0.0082
Brugia malayi RNA binding protein 0.0076 0.0676 0.2361
Brugia malayi Sugar transporter family protein 0.0212 0.2072 0.73
Plasmodium falciparum pyruvate kinase 0.0106 0.0984 0.1065
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.014 0.0451
Leishmania major glucose transporter, lmgt2 0.0066 0.0564 0.1916
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0082 0.0082
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0413 0.143
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.1917
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0556 0.0556
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Echinococcus granulosus pyruvate kinase 0.0055 0.045 0.0529
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0637 0.075
Brugia malayi intermediate filament protein 0.0026 0.0155 0.0518
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.2906 1
Echinococcus multilocularis nibrin 0.0012 0.0009 0.0009
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0674 0.2296
Onchocerca volvulus 0.003 0.0194 0.1855
Plasmodium falciparum protein kinase 6 0.0898 0.9165 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0344 0.1183
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0564 0.2691
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0301 0.293
Echinococcus granulosus neuropeptide receptor A26 0.0466 0.4694 0.5527
Giardia lamblia Prolyl-tRNA synthetase 0.0064 0.0542 0.5469
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0194 0.0653
Chlamydia trachomatis threonine--tRNA ligase 0.0012 0.0009 0.0002
Echinococcus granulosus solute carrier family 22 0.003 0.0194 0.0228
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.1917
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0118 1
Echinococcus multilocularis tumor protein p63 0.0408 0.4101 0.4101
Loa Loa (eye worm) hypothetical protein 0.0057 0.0478 0.1658
Echinococcus granulosus tar DNA binding protein 0.0076 0.0676 0.0796
Plasmodium falciparum calcium-dependent protein kinase 3 0.0065 0.0556 0.0597
Toxoplasma gondii pyruvate kinase PyKII 0.0055 0.045 0.0728
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0017 0.006 0.0084
Mycobacterium tuberculosis Probable hydrolase 0.0108 0.1004 0.1417
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0009 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.006 0.0346
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0082 0.0097
Onchocerca volvulus 0.003 0.0194 0.1855
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0017 0.006 0.0071
Schistosoma mansoni pyruvate kinase 0.0106 0.0984 0.1158
Echinococcus multilocularis solute carrier family 22 0.003 0.0194 0.0194
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0017 0.006 0.0511
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0032 0.0218 0.074
Echinococcus multilocularis protein dispatched 1 0.0058 0.0488 0.0488
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0676 0.0796
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0413 0.0413
Trypanosoma brucei glucose transporter 2A 0.0066 0.0564 0.1917
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0564 0.1917
Schistosoma mansoni protein kinase 0.0065 0.0556 0.0654
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0082 0.008
Brugia malayi AMP-binding enzyme family protein 0.0017 0.006 0.018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0258
Toxoplasma gondii ATPase, AAA family protein 0.0012 0.0009 0.00000057275
Schistosoma mansoni pyruvate kinase 0.0055 0.045 0.0529
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Loa Loa (eye worm) hypothetical protein 0.0052 0.0419 0.1451
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0082 0.6704
Plasmodium falciparum protein kinase 7 0.0598 0.6063 0.6612
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0258
Schistosoma mansoni hypothetical protein 0.0212 0.2072 0.244
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0017 0.006 0.0346
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.003 0.0194 0.0263
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0493 0.33
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0082 0.1097
Schistosoma mansoni cpg binding protein 0.0029 0.0185 0.0218
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0503 0.0592
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0057 0.0478 0.3193
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0212 0.2072 0.244
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0674 0.2296
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.1004 0.1182
Entamoeba histolytica acyl-coA synthetase, putative 0.0057 0.0478 0.424
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0009 0.0009
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.1917
Loa Loa (eye worm) hypothetical protein 0.0035 0.0247 0.084
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0065 0.0556 0.0597
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0676 0.0676
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0017 0.006 0.018
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.2836 0.2836
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.1917
Echinococcus granulosus pyruvate kinase 0.0106 0.0984 0.1158
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0413 0.0487
Schistosoma mansoni cpg binding protein 0.0031 0.0202 0.0238
Loa Loa (eye worm) hypothetical protein 0.0119 0.1114 0.391
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0478 0.3193
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0342 0.3419 0.3724
Echinococcus multilocularis pyruvate kinase 0.0055 0.045 0.045
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0155 0.0518
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.1004 0.3435
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.006 0.0346
Mycobacterium ulcerans esterase/lipase LipP 0.0108 0.1004 0.678
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.0374 0.1261
Brugia malayi jmjC domain containing protein 0.0019 0.0082 0.0258
Loa Loa (eye worm) hypothetical protein 0.0017 0.006 0.018
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0108 0.1004 0.1417
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0082 0.0258
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.1315 0.4509
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.2836 0.3339
Loa Loa (eye worm) hypothetical protein 0.0108 0.1004 0.3521
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0155 0.0518
Trypanosoma brucei sugar transporter, putative 0.003 0.0194 0.0637
Schistosoma mansoni survival motor neuron protein 0.0058 0.0488 0.0574
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0017 0.006 0.0346
Plasmodium falciparum calcium-dependent protein kinase 1 0.0065 0.0556 0.0597
Echinococcus multilocularis pyruvate kinase 0.0055 0.045 0.045
Entamoeba histolytica pyruvate kinase, putative 0.0074 0.0652 0.5814
Entamoeba histolytica protein kinase, putative 0.0065 0.0556 0.4946
Loa Loa (eye worm) fli-1 protein 0.0213 0.2084 0.7341
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0009 0.0001
Leishmania major 4-coumarate:coa ligase-like protein 0.0057 0.0478 0.1617
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0637 0.2221
Plasmodium vivax hexose transporter 0.0212 0.2072 0.2254
Loa Loa (eye worm) sugar transporter 0.0212 0.2072 0.73
Onchocerca volvulus 0.003 0.0194 0.1855
Mycobacterium ulcerans acetyl-CoA synthetase 0.0017 0.006 0.0346
Toxoplasma gondii protein kinase, putative 0.0598 0.6063 1
Plasmodium vivax CDK-related protein kinase 6, putative 0.0898 0.9165 1
Schistosoma mansoni glucose transport protein 0.0212 0.2072 0.244
Plasmodium vivax JmjC domain containing protein 0.0019 0.0082 0.008
Loa Loa (eye worm) oxidoreductase 0.0017 0.006 0.018
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0118 0.1117
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0017 0.006 0.0072
Mycobacterium ulcerans lipase LipD 0.0108 0.1004 0.678
Echinococcus multilocularis solute carrier family 22 0.003 0.0194 0.0194
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.1315 0.4509
Mycobacterium ulcerans hypothetical protein 0.0057 0.0478 0.3193
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0194 0.1258
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0082 0.0097
Trichomonas vaginalis pyruvate kinase, putative 0.0106 0.0984 0.4724
Trypanosoma cruzi hexose transporter, putative 0.003 0.0194 0.0637
Schistosoma mansoni hypothetical protein 0.0035 0.0247 0.029
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.006 0.0346
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.003 0.0194 0.0637
Mycobacterium ulcerans sugar transporter 0.003 0.0194 0.1258
Toxoplasma gondii pyruvate kinase PyK1 0.0106 0.0984 0.161
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.1114 0.1114
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.1917
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.0651 0.2215
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0247 0.0247
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0674 0.3224
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0009 0.0001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.011 0.1025 0.3593
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.004 0.0304 0.042
Onchocerca volvulus 0.003 0.0194 0.1855
Echinococcus granulosus GA binding protein alpha chain 0.007 0.061 0.0719
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Loa Loa (eye worm) pigment dispersing factor receptor c 0.011 0.1025 0.3593
Giardia lamblia Hexose transporter 0.003 0.0194 0.1894
Onchocerca volvulus 0.0017 0.006 0.0511
Echinococcus multilocularis pyruvate kinase 0.0084 0.0753 0.0753
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0564 0.2691
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0082 0.0258
Schistosoma mansoni DNA ligase IV 0.0012 0.0009 0.0011
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.0374 0.3747
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.014 0.0143
Echinococcus granulosus solute carrier family 22 0.003 0.0194 0.0228
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0247 0.029
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0082 0.0251
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0493 0.33
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0099 0.0117
Onchocerca volvulus 0.0058 0.0488 0.4811
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0017 0.006 0.0346
Leishmania major glucose transporter, lmgt1 0.0066 0.0564 0.1916
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0017 0.006 0.0346
Plasmodium falciparum calcium-dependent protein kinase 2 0.0065 0.0556 0.0597
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0082 0.0252
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0311 0.1042
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0009 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0676 0.0796
Brugia malayi major facilitator superfamily protein 0.003 0.0194 0.0653
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0064 0.0542 0.0638
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0194 0.0653
Loa Loa (eye worm) hypothetical protein 0.0108 0.1004 0.3521
Trypanosoma cruzi glucose transporter, putative 0.003 0.0194 0.0637
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0009 0.0011
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0194 0.0194
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0074 0.0651 0.106
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.1004 0.3435
Echinococcus granulosus tumor protein p63 0.0408 0.4101 0.4828
Echinococcus multilocularis solute carrier family 22 0.003 0.0194 0.0194
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0017 0.006 0.0176
Loa Loa (eye worm) hypothetical protein 0.0026 0.0151 0.05
Loa Loa (eye worm) RNA binding protein 0.0076 0.0676 0.2361
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0493 0.33
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0344 0.0344
Entamoeba histolytica acyl-CoA synthetase, putative 0.0057 0.0478 0.424
Loa Loa (eye worm) pyruvate kinase 0.0106 0.0984 0.3448
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0556 0.0654
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.1133 0.1334
Schistosoma mansoni inositol monophosphatase 0.0076 0.0674 0.0794
Leishmania major protein kinase, putative 0.0065 0.0556 0.1887
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.0651 0.2215
Echinococcus granulosus solute carrier family 22 0.003 0.0194 0.0228
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.014 0.0451
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0068 0.0592 0.5855
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0194 0.0228
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0065 0.0556 0.0904
Leishmania major hypothetical protein, conserved 0.0108 0.1004 0.3435
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Loa Loa (eye worm) hypothetical protein 0.0106 0.0984 0.3448
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0009 0.0009
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0017 0.006 0.0346
Leishmania major 4-coumarate:coa ligase-like protein 0.0057 0.0478 0.1617
Schistosoma mansoni pyruvate kinase 0.0106 0.0984 0.1158
Brugia malayi Fli-1 protein 0.0213 0.2084 0.7341
Echinococcus granulosus lamin dm0 0.0026 0.0155 0.0183
Plasmodium falciparum hexose transporter 0.0212 0.2072 0.2254
Plasmodium vivax proline--tRNA ligase, putative 0.0074 0.0651 0.0701
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0057 0.0478 0.3193
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0556 0.0556
Leishmania major glucose transporter/membrane transporter D2, putative 0.0066 0.0564 0.1916
Mycobacterium tuberculosis Probable lipase LipE 0.0108 0.1004 0.1417
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0009 0.0001
Echinococcus granulosus expressed conserved protein 0.0112 0.104 0.1224
Onchocerca volvulus 0.003 0.0194 0.1855
Plasmodium vivax hypothetical protein, conserved 0.0108 0.1004 0.1087
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0564 0.2691
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0676 0.0796
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0057 0.0478 0.3193
Schistosoma mansoni inositol monophosphatase 0.0076 0.0674 0.0794
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0065 0.0556 0.1934
Loa Loa (eye worm) hypothetical protein 0.0051 0.0413 0.143
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0082 0.0354
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0342 0.3419 0.5632
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0009 0.0001
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0212 0.2072 0.2072
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Echinococcus granulosus General substrate transporter 0.0182 0.1765 0.2078
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0564 0.2691
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0076 0.0674 0.6019
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0017 0.006 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0194 0.0895
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0009 0.0001
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0065 0.0556 0.0904
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.006 0.0072
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0076 0.0674 1
Echinococcus multilocularis solute carrier family 22 0.003 0.0194 0.0194
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0556 0.0654
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0258
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Trypanosoma cruzi sugar transporter, putative 0.003 0.0194 0.0637
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0008
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0212 0.2072 0.244
Schistosoma mansoni protein kinase 0.0065 0.0556 0.0654
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0017 0.006 0.0072
Onchocerca volvulus 0.0057 0.0478 0.4709
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0082 0.008
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0194 0.0895
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0194 0.0194
Leishmania major hypothetical protein, conserved 0.0019 0.0082 0.0251
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.1917
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0082 0.0082
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0065 0.0556 0.0597
Schistosoma mansoni hypothetical protein 0.0347 0.3468 0.4084
Trypanosoma cruzi pyruvate kinase 2, putative 0.0106 0.0984 0.3365
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0478 0.3193
Schistosoma mansoni glucose transport protein 0.0212 0.2072 0.244
Onchocerca volvulus 0.0108 0.1004 1
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0194 0.0895
Brugia malayi pyruvate kinase 0.0022 0.0118 0.0384
Loa Loa (eye worm) hypothetical protein 0.0025 0.014 0.0462
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0025
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0374 0.2488
Brugia malayi beta-lactamase 0.0108 0.1004 0.3521
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0064 0.0542 0.5357
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0009 0.0001
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0194 0.0653
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.061 0.2127
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0009 0.0001
Toxoplasma gondii sugar transporter ST2 0.003 0.0194 0.0305
Schistosoma mansoni ets-related 0.0213 0.2084 0.2454
Onchocerca volvulus 0.003 0.0194 0.1855
Brugia malayi Pyruvate kinase, muscle isozyme 0.0106 0.0984 0.3448
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0017 0.006 0.0511
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Loa Loa (eye worm) hypothetical protein 0.0064 0.0542 0.1886
Onchocerca volvulus Pyruvate kinase homolog 0.0106 0.0984 0.9794
Schistosoma mansoni hypothetical protein 0.0049 0.0394 0.0464
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0009 0.0001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0057 0.0478 0.4709
Schistosoma mansoni lamin 0.0026 0.0155 0.0183
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.2906 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0057 0.0478 0.424
Mycobacterium ulcerans pyruvate kinase 0.0106 0.0984 0.6641
Giardia lamblia Sugar-proton symporter 0.003 0.0194 0.1894
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0194 0.0895
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0076 0.0674 0.4532
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0082 0.0258
Treponema pallidum threonyl-tRNA synthetase 0.0012 0.0009 0.0018
Echinococcus granulosus nibrin 0.0012 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0286 0.2836 1
Echinococcus multilocularis expressed conserved protein 0.0112 0.104 0.104
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0065 0.0556 0.1934
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.003 0.0076
Echinococcus multilocularis geminin 0.0347 0.3468 0.3468
Onchocerca volvulus Pyruvate kinase homolog 0.0106 0.0984 0.9794
Leishmania major glucose transporter, lmgt3 0.0066 0.0564 0.1916
Loa Loa (eye worm) hypothetical protein 0.0047 0.0374 0.1292
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0082 0.0104
Loa Loa (eye worm) pyruvate kinase 0.0106 0.0984 0.3448
Onchocerca volvulus 0.003 0.0194 0.1855
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0108 0.1004 0.1417
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.004 0.0304 0.042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0082 0.0252
Brugia malayi CXXC zinc finger family protein 0.0029 0.0185 0.0623
Brugia malayi AMP-binding enzyme family protein 0.0017 0.006 0.018
Plasmodium vivax calcium-dependent protein kinase, putative 0.0065 0.0556 0.0597
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0676 0.2361
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0017 0.006 0.006
Onchocerca volvulus 0.003 0.0194 0.1855
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0082 0.0749
Brugia malayi jmjC domain containing protein 0.0019 0.0082 0.0258
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0194 0.2775
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0017 0.006 0.0084
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0082 0.012
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0082 0.0251
Brugia malayi AMP-binding enzyme family protein 0.0017 0.006 0.018
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0488 0.1694
Brugia malayi hypothetical protein 0.003 0.0194 0.0653
Plasmodium vivax pyruvate kinase 2, putative 0.0055 0.045 0.0481
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0017 0.006 0.0072
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0009 0.0011
Echinococcus granulosus microtubule associated protein 2 0.0833 0.8493 1
Onchocerca volvulus 0.0017 0.006 0.0511
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0194 0.1258
Schistosoma mansoni glucose transport protein 0.0212 0.2072 0.244
Schistosoma mansoni sugar transporter 0.003 0.0194 0.0228
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.003 0.0194 0.0263
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0017 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0074 0.0652 0.2273
Echinococcus multilocularis GPCR, family 2 0.0035 0.0247 0.0247
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0556 0.0654
Trichomonas vaginalis antibiotic synthetase, putative 0.0017 0.006 0.0246
Trypanosoma cruzi pyruvate kinase 2, putative 0.0106 0.0984 0.3365
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0009 0.0011
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.2906 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0001
Mycobacterium tuberculosis Probable esterase LipL 0.0108 0.1004 0.1417
Loa Loa (eye worm) pyruvate kinase-PB 0.0074 0.0652 0.2273
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.2906 1
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0155 0.0518
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0064 0.0542 0.0542
Trypanosoma brucei glucose transporter 1E 0.0066 0.0564 0.1917
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0194 0.1258
Mycobacterium tuberculosis Conserved protein 0.0108 0.1004 0.1417
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0043 0.0328 0.1129
Echinococcus multilocularis lamin 0.0026 0.0155 0.0155
Mycobacterium leprae conserved hypothetical protein 0.0108 0.1004 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.1004 0.3521
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.014 0.0143
Schistosoma mansoni ap endonuclease 0.0019 0.0082 0.0097
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Schistosoma mansoni ap endonuclease 0.0019 0.0082 0.0097
Schistosoma mansoni sugar transporter 0.003 0.0194 0.0228
Plasmodium falciparum proline--tRNA ligase 0.0074 0.0651 0.0701
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0301 0.0415
Schistosoma mansoni sugar transporter 0.003 0.0194 0.0228
Giardia lamblia Glycyl-tRNA synthetase 0.0012 0.0009 0.0002
Giardia lamblia Pyruvate kinase 0.0106 0.0984 1
Schistosoma mansoni hypothetical protein 0.0035 0.0247 0.029
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0247 0.084
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0017 0.006 0.0056
Mycobacterium ulcerans beta-lactamase 0.0108 0.1004 0.678
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.1004 0.4823
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.052 0.0613
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0344 0.0405
Onchocerca volvulus 0.003 0.0194 0.1855
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0453 0.0733
Schistosoma mansoni hypothetical protein 0.0049 0.0394 0.0464
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0082 0.0251
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.0651 0.2215
Loa Loa (eye worm) hypothetical protein 0.0108 0.1004 0.3521
Echinococcus granulosus pyruvate kinase 0.0055 0.045 0.0529
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0082 0.0097
Loa Loa (eye worm) hypothetical protein 0.0064 0.0542 0.1886
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.006 0.0346
Brugia malayi hypothetical protein 0.003 0.0194 0.0653
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.1641 0.1932
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0212 0.2072 0.2072
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0009 0.0002
Echinococcus granulosus calcium dependent protein kinase 0.0061 0.0514 0.0606
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0082 0.0258
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Schistosoma mansoni topbp1 0.0012 0.0009 0.0011
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0108 0.1004 0.3521
Trichomonas vaginalis replication factor C large subunit, putative 0.0012 0.0009 0.0000016804
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.0374 0.0399
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0082 0.0097
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0017 0.006 0.018
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.006 0.0072
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0556 0.0556
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.062 0.062
Echinococcus multilocularis neuropeptide receptor A26 0.0466 0.4694 0.4694
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.0374 0.1261
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0017 0.006 0.018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0344 0.0344
Echinococcus multilocularis General substrate transporter 0.0182 0.1765 0.1765
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0017 0.006 0.0176
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0653
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0082 0.0097
Brugia malayi hypothetical protein 0.0286 0.2836 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0071 0.062 0.073
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0564 0.2691
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.1917
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0082 0.0097
Loa Loa (eye worm) sugar transporter 0.003 0.0194 0.0653
Toxoplasma gondii sugar transporter ST3 0.003 0.0194 0.0305
Schistosoma mansoni acetyl-CoA synthetase 0.0017 0.006 0.0071
Loa Loa (eye worm) hypothetical protein 0.0057 0.0478 0.1658
Toxoplasma gondii hypothetical protein 0.0047 0.0373 0.0602
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0564 0.1917
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0043 0.0328 0.3274
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.1641 0.1641
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Loa Loa (eye worm) hypothetical protein 0.0108 0.1004 0.3521
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0009 0.0011
Trichomonas vaginalis esterase, putative 0.0108 0.1004 0.4823
Brugia malayi pyruvate kinase, muscle isozyme 0.0022 0.0118 0.0384
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0493 0.0581
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0493 0.0581
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0009 0.0003
Loa Loa (eye worm) inositol-1 0.0076 0.0674 0.2353
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0194 0.0305
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0017 0.006 0.0072
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0692 0.7029 1
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0564 0.1917
Trichomonas vaginalis sugar transporter, putative 0.003 0.0194 0.0895
Brugia malayi CHE-14 protein 0.0051 0.0413 0.143
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0637 0.075
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0082 0.0097
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0676 0.0796
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0057 0.0478 0.0667
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0413 0.1959
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0009 0.0001
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0043 0.0328 0.0454

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.5849 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.9362 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 3.0131 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.1475 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 4.4668 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 5.1735 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 6.5131 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: Counterscreen for Luciferase (Kinase-Glo TM) Inhibition. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase (LmPK). (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Leishmania Mexicana Pyruvate Kinase (LmPK). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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