Detailed information for compound 1229167

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 293.376 | Formula: C17H24FNO2
  • H donors: 0 H acceptors: 0 LogP: 2.5 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC1COC2(C1)CCN(CC2)Cc1cccc(c1)F
  • InChi: 1S/C17H24FNO2/c1-2-20-16-11-17(21-13-16)6-8-19(9-7-17)12-14-4-3-5-15(18)10-14/h3-5,10,16H,2,6-9,11-13H2,1H3
  • InChiKey: XGRMODUKDWRDOL-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi phosphofructokinase 0.0114 0.0845 0.0837
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0186 0.0204
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0361 0.0352
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0186 0.2108
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0022 0.0145
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0107 0.0784 0.0784
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0051 0.03 0.0329
Brugia malayi hypothetical protein 0.0247 0.2008 0.2001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0101 0.0738 0.0809
Schistosoma mansoni hypothetical protein 0.087 0.7427 0.8037
Toxoplasma gondii type I fatty acid synthase, putative 0.007 0.0466 0.626
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0042 0.0225 0.0225
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0161 0.0173
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0031 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0123 0.1361
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0363 0.0392
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0286 0.0286
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0845 0.0845
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0044 0.0238 0.0261
Loa Loa (eye worm) hypothetical protein 0.0037 0.0182 0.0181
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0031 0.0033
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0051 0.03 0.0329
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.0786 0.0777
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0031 0.0021
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0101 0.0738 0.0789
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0186 0.0204
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0031 0.0033
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0101 0.0738 0.0737
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0101 0.0738 0.0729
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0186 0.0204
Loa Loa (eye worm) hypothetical protein 0.0038 0.0186 0.0185
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Loa Loa (eye worm) fatty acid synthase 0.0052 0.0308 0.0308
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0845 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0031 0.0033
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0101 0.0738 0.8716
Brugia malayi Muscleblind-like protein 0.0458 0.3843 0.3838
Brugia malayi beta-lactamase family protein 0.0038 0.0186 0.0176
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0031 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.1064 0.9118 1
Schistosoma mansoni coup transcription factor 0.002 0.0031 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.1074 0.1162
Onchocerca volvulus 0.0038 0.0186 0.1029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.1074 0.1162
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0101 0.0738 0.0737
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0053 0.0314 0.0314
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0031 0.0033
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0845 0.0927
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0186 0.02
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0845 1
Trichomonas vaginalis antibiotic synthetase, putative 0.0101 0.0738 0.8716
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0361 0.039
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0066 0.0071
Mycobacterium tuberculosis Probable thioesterase TesA 0.0044 0.0238 0.0261
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0107 0.0784 0.086
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.2008 0.2173
Schistosoma mansoni nuclear hormone receptor 0.002 0.0031 0.0033
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0845 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0738 0.0809
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0186 0.2108
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0123 0.1419
Entamoeba histolytica hypothetical protein 0.0035 0.0159 0.1794
Entamoeba histolytica acyl-CoA synthetase, putative 0.0101 0.0738 0.8716
Echinococcus multilocularis GPCR, family 2 0.0049 0.0286 0.0309
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1078 0.9241 1
Schistosoma mansoni hypothetical protein 0.0049 0.0286 0.0309
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0361 0.0361
Onchocerca volvulus 0.0101 0.0738 0.4698
Brugia malayi AMP-binding enzyme family protein 0.0101 0.0738 0.0729
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0845 1
Brugia malayi hypothetical protein 0.0035 0.0159 0.015
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0123 0.1419
Onchocerca volvulus Fatty acid synthase homolog 0.0095 0.0682 0.433
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0186 0.0185
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0031 0.0033
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.1064 0.9118 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0101 0.0738 0.0809
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0161 0.0173
Leishmania major hypothetical protein, conserved 0.0054 0.0325 0.0346
Loa Loa (eye worm) hypothetical protein 0.004 0.0202 0.0201
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0361 0.0386
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0123 0.1562
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0031 0.0033
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0286 0.0309
Leishmania major fatty acid transporter protein-like protein 0.1064 0.9118 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0361 0.0396
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0845 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0042 0.0225 0.0225
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0067 0.0057
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0031 0.0033
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0056 0.0343 0.0376
Schistosoma mansoni hypothetical protein 0.0049 0.0286 0.0309
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0053 0.0314 0.0345
Loa Loa (eye worm) hypothetical protein 0.0458 0.3843 0.3843
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0845 1
Entamoeba histolytica hypothetical protein 0.0035 0.0159 0.1794
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0043 0.0231 0.0253
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0738 0.0809
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0031 0.0021
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0186 0.2108
Brugia malayi 6-phosphofructokinase 0.0114 0.0845 0.0837
Brugia malayi Bromodomain containing protein 0.0073 0.0493 0.0484
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0031 0.0033
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0019 0.0025 0.0025
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0107 0.0784 0.086
Loa Loa (eye worm) beta-lactamase 0.0038 0.0186 0.0185
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0107 0.0784 0.0784
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0031 0.0033
Schistosoma mansoni zinc finger protein 0.0019 0.0022 0.0023
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0066 0.0071
Loa Loa (eye worm) hypothetical protein 0.0101 0.0738 0.0737
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0123 0.5
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0295 0.0286
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0031 0.003
Brugia malayi Calcitonin receptor-like protein seb-1 0.0156 0.1216 0.1208
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0123 0.1361
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0013
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0022 0.0021
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0107 0.0784 0.086
Brugia malayi AMP-binding enzyme family protein 0.0101 0.0738 0.0729
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0031 0.0021
Toxoplasma gondii exonuclease III APE 0.0019 0.0022 0.0166
Mycobacterium tuberculosis Conserved protein 0.0038 0.0186 0.0204
Echinococcus granulosus long chain fatty acid transport protein 4 0.1078 0.9241 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0058 0.0057
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0845 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0123 0.1361
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0845 0.0845
Trichomonas vaginalis esterase, putative 0.0038 0.0186 0.2108
Entamoeba histolytica hypothetical protein 0.0035 0.0159 0.1794
Loa Loa (eye worm) acyl carrier protein 0.0024 0.0067 0.0066
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0186 0.02
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0159 0.0172
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0056 0.0343 0.0376
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0156 0.1216 0.1208
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0186 0.0186
Schistosoma mansoni survival motor neuron protein 0.005 0.0295 0.0318
Leishmania major cytochrome p450-like protein 0.0023 0.0058 0.0053
Entamoeba histolytica acyl-CoA synthetase, putative 0.0019 0.0025 0.0184
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0286 0.0309
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0047 0.005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0031 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0186 0.02
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0101 0.0738 0.0798
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.003
Mycobacterium ulcerans thioesterase TesA 0.0044 0.0238 0.0238
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0107 0.0784 0.0784
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.001 0.0009
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0041 0.021 0.2756
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0101 0.0738 0.0738
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0058 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0107 0.0784 0.0775
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0101 0.0738 0.0809
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.0935 0.0934
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0101 0.0738 0.0738
Loa Loa (eye worm) hypothetical protein 0.0107 0.0786 0.0785
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0845 0.0927
Mycobacterium ulcerans hypothetical protein 0.0038 0.0186 0.0186
Mycobacterium ulcerans Type I modular polyketide synthase 0.0053 0.0314 0.0314
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0101 0.0738 0.0738
Mycobacterium ulcerans Type I modular polyketide synthase 0.0053 0.0314 0.0314
Brugia malayi 6-phosphofructokinase 0.0114 0.0845 0.0837
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0186 0.0204
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0325 0.0342
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.1074 0.1162
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.1074 0.1162
Brugia malayi beta-lactamase 0.0038 0.0186 0.0176
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0022 0.0023
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0286 0.0277
Schistosoma mansoni hypothetical protein 0.0049 0.0286 0.0309
Schistosoma mansoni bromodomain containing protein 0.0062 0.0393 0.0425
Mycobacterium leprae Polyketide synthase Pks13 0.0079 0.0541 0.0594
Loa Loa (eye worm) oxidoreductase 0.0101 0.0738 0.0737
Entamoeba histolytica hypothetical protein 0.0024 0.0067 0.0686
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0058 0.0057
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0845 0.0845
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0022 0.0022
Mycobacterium ulcerans hypothetical protein 0.0101 0.0738 0.0738
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0022 0.0024
Loa Loa (eye worm) AMP-binding enzyme family protein 0.015 0.1166 0.1166
Echinococcus granulosus geminin 0.087 0.7427 0.8037
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0006 0.0005
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0845 0.0905
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0186 0.0186
Toxoplasma gondii propionate-CoA ligase 0.0101 0.0738 1
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0101 0.0738 0.08
Mycobacterium ulcerans polyketide synthase 0.0056 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0286 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0031 0.0021
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0101 0.0738 0.0738
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.1074 0.1066
Brugia malayi steroid hormone receptor 0.002 0.0031 0.0021
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0053 0.0314 0.0345
Mycobacterium ulcerans lipase LipD 0.0038 0.0186 0.0186
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0056 0.0343 0.0376
Schistosoma mansoni hypothetical protein 0.002 0.0031 0.0033
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0363 0.0392
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.001 0.0009
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0042 0.0225 0.0247
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0186 0.0191
Loa Loa (eye worm) hypothetical protein 0.0029 0.0113 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0031 0.0021
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.1165 1 1
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0107 0.0784 0.086
Schistosoma mansoni hypothetical protein 0.0107 0.0786 0.0849
Loa Loa (eye worm) AMP-binding enzyme family protein 0.1165 1 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0286 0.0309
Onchocerca volvulus 0.0038 0.0186 0.1029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0738 0.0809
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0145
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0067 0.0072
Leishmania major 4-coumarate:coa ligase-like protein 0.0101 0.0738 0.08
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0079 0.0541 0.0594
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0031 0.0033
Mycobacterium tuberculosis Conserved protein 0.0038 0.0186 0.0204
Loa Loa (eye worm) hypothetical protein 0.0038 0.0186 0.0185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0031 0.003
Mycobacterium tuberculosis Conserved protein 0.0038 0.0186 0.0204
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0031 0.003
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0101 0.0738 0.0789
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0101 0.0738 0.0789
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0018 0.0014 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0031 0.003
Plasmodium vivax acetyl-CoA synthetase, putative 0.0101 0.0738 1
Echinococcus granulosus muscleblind protein 0.0458 0.3843 0.4159
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0325 0.4233
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0101 0.0738 0.0809
Leishmania major acetyl-CoA synthetase, putative 0.0101 0.0738 0.08
Schistosoma mansoni hypothetical protein 0.0049 0.0286 0.0309
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0031 0.0021
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0845 0.0914
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0031 0.0033
Mycobacterium ulcerans acyl-CoA synthetase 0.0107 0.0784 0.0784
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0067 0.0787
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0053 0.0314 0.0305
Loa Loa (eye worm) hypothetical protein 0.0156 0.1216 0.1215
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0149 0.0148
Entamoeba histolytica acyl-coA synthetase, putative 0.0101 0.0738 0.8716
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0079 0.0541 0.0594
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0123 0.1361
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0361 0.039
Brugia malayi AMP-binding enzyme family protein 0.0101 0.0738 0.0729
Leishmania major hypothetical protein, conserved 0.0038 0.0186 0.0193
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0038 0.0185 0.0203
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0325 0.3773
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0056 0.0343 0.0376
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0031 0.0033
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0056 0.0343 0.0343
Brugia malayi nuclear hormone receptor 0.002 0.0031 0.0021
Echinococcus granulosus FTZ F1 alpha 0.002 0.0031 0.0033
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0123 1
Leishmania major pantothenate kinase subunit, putative 0.0018 0.0012 0.0003
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0361 0.039
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0031 0.0021
Echinococcus multilocularis AMP dependent ligase 0.0019 0.0025 0.0026
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0031 0.0033
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0031 0.0033
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0025 0.0027
Echinococcus granulosus GPCR family 2 0.0049 0.0286 0.0309
Leishmania major 4-coumarate:coa ligase-like protein 0.0101 0.0738 0.08
Loa Loa (eye worm) hypothetical protein 0.0101 0.0738 0.0737
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0107 0.0784 0.086
Schistosoma mansoni hypothetical protein 0.087 0.7427 0.8037
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0067 0.0062
Brugia malayi AMP-binding enzyme family protein 0.0101 0.0738 0.0729
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0845 0.0845
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.1074 0.1162
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0186 0.229
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0101 0.0738 0.0738
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0186 0.2108
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.1962 0.2152
Echinococcus multilocularis geminin 0.087 0.7427 0.8037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0031 0.0033
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0101 0.0738 0.0809
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0022 0.5
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.003
Onchocerca volvulus 0.005 0.0295 0.1755
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0145
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0186 0.0176
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0058 0.0052
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0101 0.0738 0.0809
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0159 0.0172
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0031 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0031 0.0033
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.2008 0.2173
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0123 0.1361
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0021 0.0041 0.0045
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0067 0.0072
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0101 0.0738 0.8716
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0031 0.0033
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0101 0.0738 1
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0031 0.0033
Brugia malayi ecdysteroid receptor 0.002 0.0031 0.0021
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0845 0.0914
Mycobacterium ulcerans Type I modular polyketide synthase 0.0053 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.003
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0047 0.005
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0067 0.0072
Brugia malayi Cytochrome P450 family protein 0.0023 0.0058 0.0048
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0107 0.0784 0.0784
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0031 0.003
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.015 0.1166 0.1279
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0025 0.0027
Onchocerca volvulus 0.0038 0.0186 0.1029
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0123 0.1361
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0031 0.0021
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.003 0.0117 0.0128
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0067 0.0686
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0031 0.003
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0047 0.005
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1078 0.9241 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0101 0.0738 0.0738
Schistosoma mansoni hypothetical protein 0.0024 0.0066 0.0071
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0123 0.1562
Leishmania major 4-coumarate:coa ligase-like protein 0.0101 0.0738 0.08
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0031 0.003
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0031 0.0033
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0101 0.0738 0.0789
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.1074 0.1162
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0123 0.1361
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0101 0.0738 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0031 0.0021
Mycobacterium ulcerans polyketide synthase Pks9 0.0035 0.0159 0.0159
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0325 0.4233
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.003
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.003
Onchocerca volvulus 0.0111 0.0818 0.5232
Brugia malayi hypothetical protein 0.0054 0.0325 0.0316
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.001 0.0009
Brugia malayi beta-lactamase family protein 0.0038 0.0186 0.0176
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0018 0.0012 0.0003
Brugia malayi Bromodomain containing protein 0.0037 0.0181 0.0172
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0031 0.0033
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0186 0.0204
Schistosoma mansoni hypothetical protein 0.0035 0.0159 0.0172
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0845 0.0914
Loa Loa (eye worm) hypothetical protein 0.0038 0.0186 0.0185
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0159 0.0172
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0186 0.02
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0327 0.0326
Loa Loa (eye worm) hypothetical protein 0.0038 0.0186 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0031 0.0021
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0022 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0186 0.2108
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0053 0.0314 0.0345
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0031 0.0033
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0156 0.1216 0.1215
Mycobacterium ulcerans polyketide synthase 0.0053 0.0314 0.0314
Brugia malayi hypothetical protein 0.0035 0.0159 0.0149
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.001 0.0009
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0037 0.003
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0031 0.003
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0186 0.0204
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0031 0.0033
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0058 0.0052
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0031 0.0033
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0186 0.0204
Brugia malayi AMP-binding enzyme family protein 0.015 0.1166 0.1158
Brugia malayi AMP-binding enzyme family protein 0.003 0.012 0.011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0037
Brugia malayi AMP-binding enzyme family protein 0.0101 0.0738 0.0729
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.01 0.0725 0.0716
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0738 0.0809
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0053 0.0314 0.0345
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0031 0.0021
Brugia malayi PHD-finger family protein 0.0024 0.0067 0.0058
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0035 0.0159 0.0159
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0145
Schistosoma mansoni thyroid hormone receptor 0.002 0.0031 0.0033
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.001 0.0009
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0845 0.0914
Loa Loa (eye worm) hypothetical protein 0.0054 0.0325 0.0324
Echinococcus multilocularis muscleblind protein 0.0458 0.3843 0.4159
Loa Loa (eye worm) hypothetical protein 0.0049 0.0286 0.0286
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0034 0.0153 0.1975
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0101 0.0738 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0325 0.4233
Echinococcus granulosus zinc finger protein 0.0019 0.0022 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0325 0.0342
Brugia malayi nuclear receptor NHR-88 0.002 0.0031 0.0021
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0087 0.0615 0.0675
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0031 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0067 0.0686
Loa Loa (eye worm) hypothetical protein 0.0038 0.0186 0.0185
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0845 1
Onchocerca volvulus 0.015 0.1166 0.7544
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.001 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.0738 0.0738
Schistosoma mansoni thyroid hormone receptor 0.002 0.0031 0.0033
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0186 0.0204
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0123 0.1419
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0058 0.0578
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.003
Echinococcus granulosus AMP dependent ligase 0.0019 0.0025 0.0026
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0845 0.0918
Mycobacterium ulcerans thioesterase 0.0044 0.0238 0.0238
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0035 0.0159 0.0175
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0361 0.0361
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0022 0.0013
Schistosoma mansoni hypothetical protein 0.005 0.0295 0.0318
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0101 0.0738 0.0738
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0058 0.0058
Echinococcus multilocularis muscleblind protein 1 0.0458 0.3843 0.4159
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0022 0.0013
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0053 0.0314 0.0345
Loa Loa (eye worm) hypothetical protein 0.0247 0.2008 0.2008
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0325 0.4329
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0738 0.0809
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0186 0.0191
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0286 0.0309
Echinococcus multilocularis long chain fatty acid transport protein 4 0.1078 0.9241 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.003
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0123 0.1419
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0101 0.0738 0.0798
Loa Loa (eye worm) hypothetical protein 0.0038 0.0186 0.0185
Schistosoma mansoni FFA transport protein 0.1078 0.9241 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0031 0.003
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0023
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0022 0.1065
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0123 0.5
Loa Loa (eye worm) hypothetical protein 0.0458 0.3843 0.3843
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0031 0.0021
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0101 0.0738 0.0809
Mycobacterium leprae Probable polyketide synthase Pks1 0.0056 0.0343 0.0376
Mycobacterium ulcerans acetyl-CoA synthetase 0.0101 0.0738 0.0738
Entamoeba histolytica hypothetical protein 0.0035 0.0159 0.1794
Brugia malayi MH2 domain containing protein 0.0124 0.0935 0.0926
Mycobacterium leprae Probable lipase LipE 0.0038 0.0186 0.0204
Trichomonas vaginalis antibiotic synthetase, putative 0.0101 0.0738 0.8716
Onchocerca volvulus 0.0193 0.1536 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.1074 0.1162
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0056 0.0343 0.0376
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0022 0.0023
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0845 1
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0056 0.0343 0.0343
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.0935 0.0934
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0123 0.1562
Toxoplasma gondii ABC1 family protein 0.0038 0.0186 0.2418
Loa Loa (eye worm) hypothetical protein 0.0101 0.0738 0.0737
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0123 0.1234
Schistosoma mansoni acetyl-CoA synthetase 0.0101 0.0738 0.0798
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0123 0.1361
Onchocerca volvulus 0.0101 0.0738 0.4698
Loa Loa (eye worm) hypothetical protein 0.0103 0.0749 0.0748
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0186 0.2108
Echinococcus multilocularis zinc finger protein 0.0019 0.0022 0.0023
Entamoeba histolytica acyl-CoA synthetase, putative 0.0107 0.0784 0.927
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0031 0.0033
Toxoplasma gondii type I fatty acid synthase, putative 0.0037 0.0182 0.2373
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0101 0.0738 0.8716
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.001 0.0009
Mycobacterium ulcerans polyketide synthase Pks13 0.0079 0.0541 0.0541
Brugia malayi Cytochrome P450 family protein 0.0034 0.0149 0.0139
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.1074 0.1074
Brugia malayi Cytochrome P450 family protein 0.0023 0.0058 0.0048
Mycobacterium ulcerans beta-lactamase 0.0038 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0069 0.0456 0.0456
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0031 0.0033
Leishmania major acetyl-CoA synthetase, putative 0.0101 0.0738 0.08

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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