Detailed information for compound 1463466

Basic information

Technical information
  • TDR Targets ID: 1463466
  • Name: 1-cyclopentyl-4-[(4-fluorophenyl)-(1-propan-2 -yltetrazol-5-yl)methyl]piperazine
  • MW: 372.483 | Formula: C20H29FN6
  • H donors: 0 H acceptors: 3 LogP: 3.01 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)C(c1nnnn1C(C)C)N1CCN(CC1)C1CCCC1
  • InChi: 1S/C20H29FN6/c1-15(2)27-20(22-23-24-27)19(16-7-9-17(21)10-8-16)26-13-11-25(12-14-26)18-5-3-4-6-18/h7-10,15,18-19H,3-6,11-14H2,1-2H3
  • InChiKey: KIVYCCZHJVYDQL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-cyclopentyl-4-[(4-fluorophenyl)-(1-isopropyltetrazol-5-yl)methyl]piperazine
  • 1-cyclopentyl-4-[(4-fluorophenyl)-(1-isopropyl-5-tetrazolyl)methyl]piperazine
  • 1-cyclopentyl-4-[(4-fluorophenyl)-(1-propan-2-yl-1,2,3,4-tetrazol-5-yl)methyl]piperazine
  • Oprea1_461981
  • ASN 05554250

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0122 0.0122
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.01 0.0486
Giardia lamblia DNA repair protein RAD52 0.037 0.2399 1
Onchocerca volvulus Phospholipase A2 homolog 0.0397 0.258 0.2557
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.003 0.0097
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.0366 0.1173
Echinococcus granulosus cysteine protease atg4b 0.0126 0.0768 0.2223
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0049 0.0256 0.1009
Trypanosoma cruzi heat shock protein 90, putative 0.0042 0.0208 0.0803
Trypanosoma brucei heat shock protein, putative 0.0049 0.0255 0.1004
Schistosoma mansoni cpg binding protein 0.0063 0.035 0.1012
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0143 0.0414
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0021 0.0007
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0143 0.1229
Echinococcus multilocularis heat shock protein 90 0.0049 0.0255 0.0739
Trypanosoma brucei Sterol methyltransferase, putative 0.0206 0.1301 0.5483
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0173 0.064
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.002 0.0064 0.0185
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0206 0.1301 0.5483
Trypanosoma brucei heat shock protein, putative 0.0049 0.0255 0.1004
Schistosoma mansoni tar DNA-binding protein 0.0135 0.083 0.2402
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.003 0.0097
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0151 0.0437
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0207 0.131 0.131
Entamoeba histolytica hypothetical protein 0.004 0.0194 0.0727
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0126 0.0768 0.3198
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0151 0.0483
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0173 0.1486
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0173 0.0501
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0068 0.0196
Schistosoma mansoni protein farnesyltransferase subunit beta 0.002 0.0064 0.0185
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.003 0.0088
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0151 0.0557
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0173 0.0501
Schistosoma mansoni hypothetical protein 0.0052 0.0274 0.0792
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0221 0.1403 1
Schistosoma mansoni hypothetical protein 0.0066 0.0366 0.1061
Trypanosoma brucei lanosterol synthase 0.0357 0.231 0.9804
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.003 0.0088
Onchocerca volvulus 0.0364 0.2356 0.2333
Giardia lamblia Heat shock protein HSP 90-alpha 0.0042 0.0208 0.0867
Entamoeba histolytica peptidase, C54 family 0.0049 0.0256 0.0991
Loa Loa (eye worm) norepinephrine transporter 0.0015 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0423 0.2752 0.797
Echinococcus granulosus ceramide glucosyltransferase 0.024 0.153 0.4431
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.002 0.0064 0.0185
Brugia malayi S-adenosyl-methionine cycloartenol-C24-methyltransferase 0.01 0.0598 0.1914
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.003 0.0088
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.003 0.0088
Echinococcus multilocularis tar DNA binding protein 0.0135 0.083 0.2402
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0049 0.0256 0.2204
Echinococcus granulosus heat shock protein 90 0.0049 0.0255 0.0739
Schistosoma mansoni ap endonuclease 0.0021 0.0068 0.0196
Brugia malayi hypothetical protein 0.0015 0.003 0.0097
Brugia malayi latrophilin 2 splice variant baaae 0.0142 0.0873 0.2797
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.003 0.0088
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0068 0.029
Loa Loa (eye worm) hypothetical protein 0.01 0.0595 0.0595
Echinococcus granulosus heat shock protein 0.0049 0.0255 0.0739
Loa Loa (eye worm) hypothetical protein 0.0129 0.0788 0.0788
Brugia malayi jmjC domain containing protein 0.0105 0.0629 0.2012
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0042 0.0208 0.0603
Giardia lamblia Prenyltransferase 0.002 0.0064 0.0267
Plasmodium vivax heat shock protein, putative 0.0185 0.1163 1
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0227 0.0656
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0143 0.0414
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0151 0.1117
Onchocerca volvulus 0.0149 0.0925 0.0897
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0064 0.0185
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0068 0.0201
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.0366 0.1061
Schistosoma mansoni heat shock protein 0.0032 0.0146 0.0422
Loa Loa (eye worm) acetyltransferase 0.015 0.093 0.093
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0107 0.0645 0.2673
Entamoeba histolytica heat shock protein 90, putative 0.0049 0.0255 0.0985
Brugia malayi Pre-SET motif family protein 0.0034 0.0157 0.0504
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0126 0.0768 0.4512
Schistosoma mansoni ceramide glucosyltransferase 0.024 0.153 0.4431
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0105 0.0629 0.182
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.003 0.026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0211 0.061
Brugia malayi Cytochrome P450 family protein 0.0029 0.0122 0.0389
Brugia malayi TAR-binding protein 0.0135 0.083 0.2656
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0126 0.0768 0.3198
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0173 0.0652
Trypanosoma cruzi lanosterol synthase, putative 0.0357 0.231 0.9804
Echinococcus granulosus Peptidase C54 0.0126 0.0768 0.2223
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0068 0.0068
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0274 0.0876
Toxoplasma gondii Hsp90 domain-containing protein 0.0185 0.1163 1
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0064 0.0268
Giardia lamblia Grp94/Hsp90 0.0046 0.0235 0.098
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0224 0.1923
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.003 0.0088
Schistosoma mansoni hypothetical protein 0.0529 0.3454 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0068 0.0582
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.003 0.0088
Giardia lamblia Heat shock protein HSP 90-alpha 0.0049 0.0255 0.1063
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Plasmodium falciparum amino acid transporter, putative 0.0015 0.003 0.026
Leishmania major heat shock protein, putative 0.0032 0.0146 0.0536
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.01 0.0595 0.1722
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0032 0.0146 0.0526
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0068 0.0196
Schistosoma mansoni hypothetical protein 0.0066 0.0366 0.1061
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0129 0.0412
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0224 0.0648
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0126 0.0768 0.2223
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0173 0.0652
Loa Loa (eye worm) hypothetical protein 0.0149 0.0925 0.0925
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.00000000017513
Echinococcus multilocularis serotonin transporter 0.0015 0.003 0.0088
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.002 0.0064 0.0182
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0064
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0126 0.0768 0.3198
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.002 0.0064 0.0268
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.002 0.0064 0.0185
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.003 0.003
Schistosoma mansoni endoplasmin 0.0049 0.0255 0.0739
Mycobacterium ulcerans heat shock protein 90 0.0046 0.0235 1
Trypanosoma brucei heat shock protein, putative 0.0049 0.0255 0.1004
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0157 0.1353
Schistosoma mansoni heat shock protein 0.0049 0.0255 0.0739
Echinococcus multilocularis cysteine protease atg4b 0.0126 0.0768 0.2223
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.003 0.0088
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0046 0.0235 1
Loa Loa (eye worm) platelet-activating factor acetylhydrolase 0.0364 0.2356 0.2356
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.003 0.0088
Schistosoma mansoni hypothetical protein 0.0023 0.0082 0.0238
Loa Loa (eye worm) histone methyltransferase 0.002 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0051 0.027 0.027
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.002 0.00000000017513
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0188 0.0544
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0064 0.055
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0064 0.0186
Loa Loa (eye worm) hypothetical protein 0.0253 0.1616 0.1616
Plasmodium falciparum phd finger protein, putative 0.0032 0.0143 0.1229
Brugia malayi Calcitonin receptor-like protein seb-1 0.0207 0.131 0.4195
Schistosoma mansoni hypothetical protein 0.0032 0.0143 0.0414
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.003 0.0088
Echinococcus multilocularis vesicular acetylcholine transporter 0.0479 0.3123 0.9044
Brugia malayi Hsp90 protein 0.0032 0.0146 0.0467
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0022 0.0022
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0479 0.3123 0.3102
Schistosoma mansoni hypothetical protein 0.004 0.0194 0.0561
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.003 0.026
Giardia lamblia PHD finger protein 15 0.0032 0.0143 0.0596
Trypanosoma cruzi lanosterol synthase, putative 0.0357 0.231 0.9804
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0208 0.1137
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0143 0.1048
Brugia malayi vesicular acetylcholine transporter unc-17 0.0479 0.3123 1
Plasmodium falciparum protein farnesyltransferase subunit beta 0.002 0.0064 0.055
Plasmodium vivax amine transporter, putative 0.0015 0.003 0.0059
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0068 0.0217
Entamoeba histolytica hypothetical protein 0.004 0.0194 0.0727
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0173 0.0652
Plasmodium falciparum heat shock protein 90 0.0049 0.0255 0.2193
Entamoeba histolytica heat shock protein 90, putative 0.0049 0.0255 0.0985
Brugia malayi Endoplasmin precursor 0.0049 0.0255 0.0817
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.0366 0.1061
Onchocerca volvulus 0.0034 0.0157 0.0128
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0032 0.0146 0.0116
Plasmodium falciparum geranylgeranyltransferase, putative 0.002 0.0064 0.055
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.003 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0064 0.0185
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0199 0.0751
Treponema pallidum heat shock protein 90 0.0046 0.0235 1
Onchocerca volvulus Phospholipase A2 homolog 0.151 1 1
Brugia malayi RNA recognition motif domain containing protein 0.0135 0.083 0.2656
Trypanosoma brucei heat shock protein, putative 0.0049 0.0255 0.1004
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.037 0.037
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0173 0.6285
Trypanosoma cruzi heat shock protein 85, putative 0.0049 0.0255 0.1004
Trichomonas vaginalis heat shock protein, putative 0.0049 0.0255 0.1421
Entamoeba histolytica hypothetical protein 0.004 0.0194 0.0727
Entamoeba histolytica peptidase, C54 family 0.0049 0.0256 0.0991
Schistosoma mansoni hypothetical protein 0.0142 0.0873 0.2529
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0143 0.1229
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0082 0.0238
Echinococcus multilocularis bloom syndrome protein 0.0026 0.01 0.029
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0224 0.1923
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0064 0.0268
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0049 0.0256 0.1009
Schistosoma mansoni hypothetical protein 0.0066 0.0366 0.1061
Trypanosoma brucei heat shock protein, putative 0.0049 0.0255 0.1004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0061 0.0175
Schistosoma mansoni autophagin-1 (C54 family) 0.0126 0.0768 0.2223
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0064 0.0185
Schistosoma mansoni ap endonuclease 0.0021 0.0068 0.0196
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0173 0.0652
Loa Loa (eye worm) hypothetical protein 0.0126 0.0768 0.0768
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0151 0.0437
Toxoplasma gondii exonuclease III APE 0.0021 0.0068 0.0582
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0199 0.1713
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0157 0.0456
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0485 0.1404
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0064 0.0205
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.078 0.226
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.003 0.0097
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0036 0.0105
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Toxoplasma gondii heat shock protein 75, putative 0.0032 0.0146 0.1254
Brugia malayi hypothetical protein 0.0253 0.1616 0.5174
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0064 0.0185
Schistosoma mansoni tar DNA-binding protein 0.0135 0.083 0.2402
Onchocerca volvulus 0.0364 0.2356 0.2333
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0206 0.1301 0.5483
Plasmodium vivax hypothetical protein, conserved 0.0015 0.003 0.0059
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0064 0.0205
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0079 0.0683
Schistosoma mansoni vesicular acetylcholine transporter 0.0479 0.3123 0.9044
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.01 0.0595 0.1722
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.00000000017513
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Trypanosoma cruzi Heat shock protein 83, putative 0.0049 0.0255 0.1004
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.027 0.2318
Brugia malayi hypothetical protein 0.0149 0.0925 0.2962
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0194 0.0561
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0049 0.0256 0.1009
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.0366 0.0366
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0479 0.3123 0.3123
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0211 0.061
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0224 0.1232
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0061 0.0175
Schistosoma mansoni cpg binding protein 0.0063 0.035 0.1012
Onchocerca volvulus 0.0262 0.1677 0.1652
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.00000000017513
Echinococcus granulosus GPCR family 2 0.0066 0.0366 0.1061
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0206 0.1301 0.5483
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.027 0.2159
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0068 0.1824
Trichomonas vaginalis set domain proteins, putative 0.0262 0.1677 1
Echinococcus multilocularis heat shock protein 0.0049 0.0255 0.0739
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0167 0.1042 0.4374
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.002 0.0064 0.0185
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0064 0.0268
Plasmodium falciparum transporter, putative 0.0015 0.003 0.026
Brugia malayi heat shock protein 90 0.0049 0.0255 0.0817
Echinococcus multilocularis dnaJ subfamily B 0.0423 0.2752 0.797
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.003 0.026
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0126 0.0768 0.4512
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0064 0.055
Leishmania major farnesyltransferase beta subunit 0.002 0.0064 0.0185
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0068 0.0201
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Plasmodium falciparum endoplasmin, putative 0.0035 0.0166 0.1426
Trypanosoma brucei heat shock protein 90, putative 0.0049 0.0255 0.1004
Loa Loa (eye worm) ceramide glucosyltransferase 0.024 0.153 0.153
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0064 0.0268
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0068 0.0197
Onchocerca volvulus Ceramide glucosyltransferase homolog 0.024 0.153 0.1504
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.0366 0.1061
Loa Loa (eye worm) hypothetical protein 0.0032 0.0143 0.0143
Schistosoma mansoni survival motor neuron protein 0.0052 0.0274 0.0792
Plasmodium vivax endoplasmin, putative 0.0049 0.0255 0.2032
Brugia malayi Latrophilin receptor protein 2 0.0066 0.0366 0.1173
Echinococcus multilocularis GPCR, family 2 0.0066 0.0366 0.1061
Loa Loa (eye worm) serotonin transporter b 0.0015 0.003 0.003
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0064 0.0185
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.027 0.1066
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.002 0.0064 0.0268
Toxoplasma gondii heat shock protein 90, putative 0.0049 0.0255 0.2193
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0206 0.1301 0.5483
Loa Loa (eye worm) hypothetical protein 0.01 0.0598 0.0598
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.003 0.003
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0045 0.0187
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0151 0.0437
Loa Loa (eye worm) RNA binding protein 0.0135 0.083 0.083
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0173 0.0925
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.027 0.1066
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0036 0.0105
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0151 0.0437
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0151 0.0557
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0151 0.0623
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0106 0.0307
Entamoeba histolytica hypothetical protein 0.0105 0.0632 0.2571
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0064 0.0355
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.093 0.2693
Echinococcus multilocularis survival motor neuron protein 1 0.0253 0.1616 0.4679
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.00000000017513
Schistosoma mansoni tar DNA-binding protein 0.0135 0.083 0.2402
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0064 0.0064
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.002 0.0064 0.055
Loa Loa (eye worm) heat shock protein 75 0.0032 0.0146 0.0146
Toxoplasma gondii hypothetical protein 0.0015 0.003 0.026
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0044 0.0374
Schistosoma mansoni endoplasmin 0.0049 0.0255 0.0739
Echinococcus multilocularis geminin 0.0529 0.3454 1
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0119 0.0599
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.027 0.2318
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0143 0.0414
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0151 0.0437
Leishmania major phospholipase A1, putative 0.0364 0.2356 1
Trypanosoma brucei Heat shock protein 83, putative 0.0049 0.0255 0.1004
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0068 0.0282
Entamoeba histolytica peptidase, C54 family 0.0126 0.0768 0.314
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0143 0.0143
Leishmania major sterol 24-c-methyltransferase, putative 0.0206 0.1301 0.5483
Trypanosoma brucei heat shock protein 90, putative 0.0049 0.0255 0.1004
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0151 0.1297
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.002 0.00000000017513
Trypanosoma brucei heat shock protein, putative 0.0049 0.0255 0.1004
Toxoplasma gondii heat shock protein HSP90 0.0049 0.0255 0.2193
Trypanosoma cruzi heat shock protein 85, putative 0.0049 0.0255 0.1004
Loa Loa (eye worm) hypothetical protein 0.0397 0.258 0.258
Schistosoma mansoni hypothetical protein 0.0066 0.0366 0.1061
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0194 0.0561
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0207 0.131 0.4195
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.0366 0.1061
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.003 0.0097
Leishmania major hypothetical protein, conserved 0.0051 0.027 0.1066
Loa Loa (eye worm) hypothetical protein 0.0142 0.0873 0.0873
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.002 0.0064 0.0182
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0151 0.0557
Echinococcus granulosus endoplasmin 0.0046 0.0235 0.0681
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.037 0.2399 1
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.093 0.2693
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.002 0.0064 0.0182
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0036 0.0105
Echinococcus multilocularis Peptidase C54 0.0126 0.0768 0.2223
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0157 0.0456
Echinococcus granulosus cpg binding protein 0.0063 0.035 0.1012
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0715 0.6145
Loa Loa (eye worm) endoplasmin 0.0049 0.0255 0.0255
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0068 0.029
Brugia malayi hypothetical protein 0.0051 0.027 0.0863
Brugia malayi hypothetical protein 0.0033 0.0149 0.0477
Echinococcus granulosus serotonin transporter 0.0015 0.003 0.0088
Trichomonas vaginalis heat shock protein, putative 0.0046 0.0235 0.13
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0082 0.0238
Schistosoma mansoni tar DNA-binding protein 0.0135 0.083 0.2402
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0064 0.055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0157 0.0456
Trichomonas vaginalis heat shock protein, putative 0.0046 0.0235 0.13
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0157 0.0456
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0046 0.0235 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0157 0.0157
Schistosoma mansoni inositol monophosphatase 0.0036 0.0173 0.0501
Echinococcus granulosus peregrin 0.0036 0.0168 0.0485
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0141 0.0407
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0032 0.0146 0.0422
Onchocerca volvulus 0.0052 0.0274 0.0244
Brugia malayi PHD-finger family protein 0.0014 0.0022 0.007
Echinococcus granulosus tar DNA binding protein 0.0135 0.083 0.2402
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0032 0.0146 0.0422
Echinococcus multilocularis ceramide glucosyltransferase 0.024 0.153 0.4431
Trypanosoma cruzi phospholipase A1, putative 0.0364 0.2356 1
Brugia malayi Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein 0.0364 0.2356 0.7542
Plasmodium vivax farnesyltransferase beta subunit, putative 0.002 0.0064 0.0355
Loa Loa (eye worm) heat shock protein 90 0.0049 0.0255 0.0255
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.093 0.2977
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0066 0.0194
Echinococcus granulosus geminin 0.0529 0.3454 1
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0194 0.0561
Echinococcus granulosus heat shock protein 90 0.0042 0.0208 0.0603
Plasmodium falciparum cysteine protease ATG4, putative 0.0049 0.0256 0.2204
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0147 0.0597
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Brugia malayi Pre-SET motif family protein 0.023 0.1466 0.4694
Trypanosoma brucei phospholipase A1, putative 0.0364 0.2356 1
Plasmodium vivax SET domain protein, putative 0.0034 0.0157 0.1174
Echinococcus multilocularis endoplasmin 0.0046 0.0235 0.0681
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0014 0.0024 0.0203
Onchocerca volvulus 0.0364 0.2356 0.2333
Plasmodium falciparum heat shock protein 90, putative 0.0185 0.1163 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0157 0.0456
Echinococcus multilocularis cpg binding protein 0.0063 0.035 0.1012
Trichomonas vaginalis endoplasmin, putative 0.0035 0.0166 0.0882
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.003 0.0088
Brugia malayi Ceramide glucosyltransferase 0.024 0.153 0.4899
Trypanosoma brucei heat shock protein 84, putative 0.0032 0.0146 0.0536
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0151 0.1297
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0126 0.0768 0.4512
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.003 0.0088
Echinococcus granulosus vesicular acetylcholine transporter 0.0479 0.3123 0.9044
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0126 0.0768 0.2223
Loa Loa (eye worm) RecQ helicase 0.0026 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Brugia malayi hypothetical protein 0.004 0.0194 0.062
Echinococcus granulosus survival motor neuron protein 1 0.0253 0.1616 0.4679
Trichomonas vaginalis heat shock protein, putative 0.0035 0.0166 0.0882
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.002 0.0064 0.0185
Loa Loa (eye worm) inositol-1 0.0036 0.0173 0.0173
Schistosoma mansoni inositol monophosphatase 0.0036 0.0173 0.0501
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0206 0.1301 0.5483
Echinococcus multilocularis peregrin 0.0036 0.0168 0.0485
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0173 0.0925
Leishmania major sterol 24-c-methyltransferase, putative 0.0206 0.1301 0.5483
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0046 0.0235 0.1254
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Trypanosoma cruzi heat shock protein 85, putative 0.0042 0.0208 0.0803
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0157 0.0456
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0014 0.0021 0.0061
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0015 0.003 0.5
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0064 0.0268
Trypanosoma brucei heat shock protein, putative 0.0049 0.0255 0.1004
Trypanosoma brucei protein farnesyltransferase beta subunit 0.002 0.0064 0.0185
Brugia malayi jmjC domain containing protein 0.0042 0.0211 0.0674
Trichomonas vaginalis DNA helicase recq1, putative 0.0026 0.01 0.0486
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0064 0.0268
Plasmodium vivax heat shock protein 90, putative 0.0032 0.0146 0.1073
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0199 0.083
Entamoeba histolytica peptidase, C54 family 0.0049 0.0256 0.0991
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0211 0.0211
Loa Loa (eye worm) TAR-binding protein 0.0135 0.083 0.083
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.01 0.0595 0.1722
Trypanosoma cruzi heat shock protein 90, putative 0.0049 0.0255 0.1004
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0151 0.1297
Schistosoma mansoni cpg binding protein 0.006 0.0327 0.0947
Trypanosoma cruzi heat shock protein, putative 0.0032 0.0146 0.0536
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.01 0.0595 0.1722
Leishmania major geranylgeranyltransferase, putative 0.002 0.0064 0.0185
Brugia malayi Phospholipase A2 family protein 0.0397 0.258 0.826
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0151 0.0437
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0135 0.083 0.083
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0014 0.0021 0.0061
Brugia malayi isocitrate dehydrogenase 0.0033 0.0151 0.0483
Leishmania major lanosterol synthase, putative 0.0337 0.2176 0.9228
Plasmodium vivax heat shock protein 86, putative 0.0049 0.0255 0.2032
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.003 0.0088
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Trypanosoma brucei heat shock protein, putative 0.0049 0.0255 0.1004
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Giardia lamblia Ceramide glucosyltransferase 0.0109 0.0655 0.2731
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.003 0.0088
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0105 0.0632 0.2571
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0068 0.0387
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0173 0.6285
Loa Loa (eye worm) hypothetical protein 0.0066 0.0366 0.0366
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.027 0.2318
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.003 0.0088
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0227 0.0656
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0211 0.061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.00000000017513
Echinococcus granulosus protein farnesyltransferase subunit beta 0.002 0.0064 0.0185
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0105 0.0629 0.182
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0151 0.0151
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0064 0.0268
Loa Loa (eye worm) solute carrier family 6 member 4 0.0015 0.003 0.003
Plasmodium vivax geranylgeranyltransferase, putative 0.002 0.0064 0.0355
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0151 0.0557
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.003 0.0088
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0327 0.0327
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0068 0.0201
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0064 0.0064
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.002 0.0064 0.0185
Echinococcus granulosus histone acetyltransferase KAT2B 0.0146 0.0902 0.2611
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0224 0.1232
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.003 0.0088
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0224 0.1756
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.002 0.0064 0.0205
Schistosoma mansoni heat shock protein 0.0049 0.0255 0.0739
Plasmodium falciparum heat shock protein 90, putative 0.0028 0.0119 0.1021
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0151 0.0557
Onchocerca volvulus Alhambra homolog 0.0032 0.0143 0.0113
Leishmania major heat shock protein 83-1 0.0049 0.0255 0.1004
Loa Loa (eye worm) hypothetical protein 0.0207 0.131 0.131
Loa Loa (eye worm) hypothetical protein 0.0055 0.0295 0.0295
Echinococcus multilocularis heat shock protein 90 0.0042 0.0208 0.0603
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0068 0.0201
Brugia malayi Inositol-1 0.0036 0.0173 0.0554
Brugia malayi PHD-finger family protein 0.0032 0.0143 0.0458
Brugia malayi CXXC zinc finger family protein 0.006 0.0327 0.1047
Onchocerca volvulus 0.006 0.0327 0.0298
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0126 0.0768 0.4512
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0167 0.1042 0.4374
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.003 0.0088
Entamoeba histolytica peptidase, C54 family 0.0049 0.0256 0.0991
Echinococcus granulosus dnaJ subfamily B 0.0423 0.2752 0.797
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0049 0.0256 0.1009
Echinococcus granulosus bloom syndrome protein 0.0026 0.01 0.029
Brugia malayi Bloom's syndrome protein homolog 0.0026 0.01 0.0321
Toxoplasma gondii hypothetical protein 0.0015 0.003 0.026
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0126 0.0768 0.4512
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0151 0.0437
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.01 0.0595 0.1722
Brugia malayi Peptidase family C54 containing protein 0.0126 0.0768 0.2458
Trypanosoma cruzi phospholipase A1, putative 0.0364 0.2356 1
Brugia malayi RNA binding protein 0.0135 0.083 0.2656
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.027 0.1066
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.003 0.0097
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0173 0.0925
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0046 0.0235 0.0918
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.023 0.1466 0.1466
Giardia lamblia Rab geranylgeranyltransferase 0.002 0.0064 0.0267
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.002 0.0064 0.0185
Schistosoma mansoni tar DNA-binding protein 0.0135 0.083 0.2402
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0157 0.0456
Schistosoma mansoni hypothetical protein 0.0529 0.3454 1
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0064 0.0185
Trypanosoma cruzi heat shock protein 85, putative 0.0049 0.0255 0.1004
Loa Loa (eye worm) hypothetical protein 0.01 0.0595 0.0595
Brugia malayi Bromodomain containing protein 0.0036 0.0168 0.0536
Entamoeba histolytica hypothetical protein 0.004 0.0194 0.0727
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0036 0.0105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.00000000017513
Schistosoma mansoni ceramide glucosyltransferase 0.024 0.153 0.4431

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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