Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0107 | 0.0109 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0035 | 0.0012 | 0.0012 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0106 | 0.0103 | 0.0601 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2264 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.4115 | 0.525 | 0.525 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0207 | 0.0232 | 0.1469 |
Wolbachia endosymbiont of Brugia malayi | acyl carrier protein | 0.0417 | 0.0502 | 0.2059 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0207 | 0.0232 | 0.1446 |
Schistosoma mansoni | carbonic anhydrase | 0.011 | 0.0107 | 0.0623 |
Leishmania major | nuclear receptor binding factor-like protein | 0.0257 | 0.0295 | 0.1878 |
Mycobacterium ulcerans | quinone reductase Qor | 0.0257 | 0.0295 | 0.0083 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0203 | 0.0227 | 0.1736 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.4115 | 0.525 | 0.6538 |
Echinococcus multilocularis | geminin | 0.0205 | 0.0229 | 0.1428 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0425 | 0.0512 | 0.0453 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0634 | 0.078 | 0.0801 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0295 | 0.0322 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.4371 | 0.558 | 0.7025 |
Mycobacterium tuberculosis | Probable acyl carrier protein AcpA (ACP) | 0.0417 | 0.0502 | 0.044 |
Mycobacterium ulcerans | thioesterase | 0.3442 | 0.4386 | 0.5436 |
Loa Loa (eye worm) | carboxylesterase | 0.1224 | 0.1538 | 0.1727 |
Plasmodium falciparum | carbonic anhydrase | 0.011 | 0.0107 | 0.0752 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0203 | 0.0227 | 0.1393 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0203 | 0.0227 | 0.0227 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0046 | 0.0025 | 0.0094 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0023 | 0.0079 |
Onchocerca volvulus | 0.7196 | 0.9208 | 0.9656 | |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.1297 | 0.1632 | 0.1833 |
Mycobacterium tuberculosis | Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) | 0.0257 | 0.0295 | 0.0173 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.1037 | 0.1297 | 1 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.2716 | 0.3454 | 0.4216 |
Mycobacterium tuberculosis | Conserved protein | 0.1244 | 0.1564 | 0.1818 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0041 | 0.0019 | 0.0062 |
Mycobacterium ulcerans | dehydrogenase | 0.0257 | 0.0295 | 0.0083 |
Echinococcus multilocularis | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0257 | 0.0295 | 0.1864 |
Schistosoma mansoni | acyl carrier protein | 0.0417 | 0.0502 | 0.3162 |
Trypanosoma brucei | Trans-2-enoyl-ACP reductase 2, putative | 0.0257 | 0.0295 | 0.2213 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.4371 | 0.558 | 0.7025 |
Schistosoma mansoni | patched 1 | 0.0046 | 0.0025 | 0.0093 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0203 | 0.0227 | 0.0245 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0103 | 0.0104 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1224 | 0.1538 | 1 |
Onchocerca volvulus | 0.0425 | 0.0512 | 0.0301 | |
Mycobacterium tuberculosis | Probable alcohol dehydrogenase Adh | 0.0257 | 0.0295 | 0.0173 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0041 | 0.0019 | 0.0014 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks3 | 0.0634 | 0.078 | 0.0801 |
Plasmodium falciparum | acyl carrier protein | 0.0417 | 0.0502 | 0.3816 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0107 | 0.0623 |
Leishmania major | d-xylulose reductase, putative | 0.0257 | 0.0295 | 0.1878 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks4 | 0.0634 | 0.078 | 0.0801 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0425 | 0.0512 | 0.0366 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase Adh | 0.0257 | 0.0295 | 0.0083 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.1037 | 0.1297 | 0.231 |
Brugia malayi | CHE-14 protein | 0.0046 | 0.0025 | 0.0025 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase | 0.0418 | 0.0503 | 0.0355 |
Brugia malayi | Carboxylesterase family protein | 0.0207 | 0.0232 | 0.0232 |
Echinococcus multilocularis | acetylcholinesterase | 0.1224 | 0.1538 | 1 |
Loa Loa (eye worm) | acyl carrier protein | 0.1899 | 0.2405 | 0.2706 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.1297 | 0.1632 | 0.1764 |
Echinococcus granulosus | Malonyl coenzyme A acyl carrier protein transacylase | 0.0261 | 0.0301 | 0.1899 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.1037 | 0.1297 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1224 | 0.1538 | 0.9836 |
Schistosoma mansoni | zinc binding dehydrogenase | 0.0257 | 0.0295 | 0.1833 |
Leishmania major | hypothetical protein, conserved | 0.1244 | 0.1564 | 1 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.2967 | 0.3776 | 0.4687 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0046 | 0.0025 | 0.0016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0046 | 0.0025 | 0.0146 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase | 0.0257 | 0.0295 | 0.5504 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase AdhC | 0.0257 | 0.0295 | 0.0083 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0035 | 0.0012 | 0.0012 |
Brugia malayi | Carboxylesterase family protein | 0.0207 | 0.0232 | 0.0232 |
Brugia malayi | Carboxylesterase family protein | 0.0207 | 0.0232 | 0.0232 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.4371 | 0.558 | 0.6973 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.294 | 0.3742 | 0.6698 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.1037 | 0.1297 | 1 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0107 | 0.0104 | 0.1906 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.4372 | 0.5581 | 1 |
Chlamydia trachomatis | acyl carrier protein | 0.0417 | 0.0502 | 0.2016 |
Toxoplasma gondii | acyl carrier protein ACP | 0.0417 | 0.0502 | 0.0881 |
Schistosoma mansoni | carbonic anhydrase-related | 0.011 | 0.0107 | 0.0623 |
Mycobacterium tuberculosis | Probable alcohol dehydrogenase AdhA | 0.0257 | 0.0295 | 0.0173 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0112 | 0.0109 | 0.0635 |
Mycobacterium tuberculosis | S-nitrosomycothiol reductase MscR | 0.0257 | 0.0295 | 0.0173 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0153 | 0.0163 | 0.0996 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.0229 | 0.1404 |
Mycobacterium ulcerans | acyl carrier protein | 0.0417 | 0.0502 | 0.0353 |
Schistosoma mansoni | gliotactin | 0.0207 | 0.0232 | 0.1423 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.1878 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.4115 | 0.525 | 0.6598 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.6158 | 0.7874 | 1 |
Mycobacterium tuberculosis | Probable NADP-dependent alcohol dehydrogenase AdhC | 0.0257 | 0.0295 | 0.0173 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.4371 | 0.558 | 0.6973 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.3308 | 0.4214 | 0.5211 |
Schistosoma mansoni | hypothetical protein | 0.0372 | 0.0443 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0295 | 0.0322 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0203 | 0.0227 | 0.1736 |
Brugia malayi | Muscleblind-like protein | 0.0106 | 0.0103 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0012 | 0.0001 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0257 | 0.0295 | 0.2264 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Brugia malayi | AMP-binding enzyme family protein | 0.1271 | 0.1598 | 0.1598 |
Brugia malayi | acyl carrier protein, mitochondrial precursor, putative | 0.0417 | 0.0502 | 0.0502 |
Echinococcus multilocularis | AMP dependent ligase | 0.0418 | 0.0503 | 0.3223 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.3308 | 0.4214 | 0.5211 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0207 | 0.0232 | 0.009 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.4371 | 0.558 | 0.6973 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Trypanosoma cruzi | acyl transferase-like protein | 0.0261 | 0.0301 | 0.2305 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0634 | 0.078 | 0.0801 |
Echinococcus multilocularis | protein patched | 0.0046 | 0.0025 | 0.0094 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.1297 | 0.1632 | 0.1906 |
Plasmodium vivax | acyl carrier protein, putative | 0.0417 | 0.0502 | 0.3816 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0203 | 0.0227 | 0.0227 |
Trypanosoma brucei | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2213 |
Loa Loa (eye worm) | hypothetical protein | 0.1224 | 0.1538 | 0.1727 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.4115 | 0.525 | 0.6538 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) | 0.0257 | 0.0295 | 0.0173 |
Mycobacterium leprae | PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 | 0.0634 | 0.078 | 0.0639 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0257 | 0.0295 | 0.2264 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.011 | 0.0107 | 0.0107 |
Echinococcus multilocularis | expressed conserved protein | 0.0101 | 0.0095 | 0.0555 |
Mycobacterium ulcerans | acyl carrier protein | 0.0417 | 0.0502 | 0.0353 |
Echinococcus granulosus | muscleblind protein | 0.0106 | 0.0103 | 0.0601 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0203 | 0.0227 | 0.0245 |
Leishmania major | quinone oxidoreductase, putative | 0.0257 | 0.0295 | 0.1878 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.1037 | 0.1297 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.0099 | 0.0093 | 0.0093 |
Mycobacterium ulcerans | NADPH quinone oxidoreductase FadB4 | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.167 | 0.2111 | 0.2527 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2264 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0107 | 0.0104 | 0.0104 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0261 | 0.0301 | 0.1868 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0038 | 0.0031 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0257 | 0.0295 | 0.0083 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.1878 |
Brugia malayi | AMP-binding enzyme family protein | 0.3866 | 0.4932 | 0.4932 |
Mycobacterium ulcerans | oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Echinococcus multilocularis | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Mycobacterium tuberculosis | Acyl carrier protein (ACP) MbtL | 0.0417 | 0.0502 | 0.044 |
Brugia malayi | ADP-specific Phosphofructokinase/Glucokinase conserved region family protein | 0.0261 | 0.0301 | 0.0301 |
Mycobacterium ulcerans | thioesterase TesA | 0.3442 | 0.4386 | 0.5436 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0112 | 0.0109 | 0.0646 |
Loa Loa (eye worm) | carboxylesterase | 0.0207 | 0.0232 | 0.025 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.2716 | 0.3454 | 0.4168 |
Mycobacterium ulcerans | oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0425 | 0.0512 | 0.0453 |
Echinococcus granulosus | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0425 | 0.0512 | 0.0366 |
Brugia malayi | Importin beta-1 subunit | 0.0035 | 0.0011 | 0.0011 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0425 | 0.0512 | 0.0453 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0153 | 0.0163 | 0.0996 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0257 | 0.0295 | 0.0083 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0046 | 0.0025 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0103 | 0.0104 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.3442 | 0.4386 | 0.5477 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0107 | 0.0109 |
Brugia malayi | Carboxylesterase family protein | 0.1224 | 0.1538 | 0.1538 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0112 | 0.0109 | 0.0646 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.1037 | 0.1297 | 0.1454 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0884 | 0.1101 | 0.7136 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD-dependent AdhB | 0.0257 | 0.0295 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Echinococcus granulosus | carbonic anhydrase II | 0.0203 | 0.0227 | 0.1417 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.011 | 0.0107 | 0.0109 |
Echinococcus granulosus | expressed conserved protein | 0.0101 | 0.0095 | 0.0555 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0112 | 0.0109 | 0.0646 |
Echinococcus multilocularis | protein dispatched 1 | 0.0053 | 0.0033 | 0.0149 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0041 | 0.0019 | 0.0062 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0425 | 0.0512 | 0.0285 |
Onchocerca volvulus | Acyl carrier protein, mitochondrial homolog | 0.0417 | 0.0502 | 0.0291 |
Trypanosoma cruzi | Acyl carrier protein, mitochondrial, putative | 0.0417 | 0.0502 | 0.3857 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2264 |
Echinococcus multilocularis | NADH dehydrogenase | 0.0417 | 0.0502 | 0.3214 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0041 | 0.0019 | 0.0062 |
Toxoplasma gondii | Zn-containing alcohol dehydrogenase | 0.0257 | 0.0295 | 0.0511 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.127 | 0.1597 | 0.1786 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0109 | 0.0106 | 0.0613 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0261 | 0.0301 | 0.1868 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0207 | 0.0232 | 0.1446 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.4115 | 0.525 | 0.6567 |
Echinococcus multilocularis | muscleblind protein | 0.0106 | 0.0103 | 0.0601 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.2088 | 0.2648 | 0.4734 |
Onchocerca volvulus | Putative alcohol dehydrogenase | 0.0257 | 0.0295 | 0.0069 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0046 | 0.0025 | 0.0094 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0107 | 0.0104 | 0.0609 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0207 | 0.0232 | 0.1446 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.2716 | 0.3454 | 0.4216 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0425 | 0.0512 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0295 | 0.0322 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.1037 | 0.1297 | 0.1297 |
Schistosoma mansoni | carbonic anhydrase-related | 0.011 | 0.0107 | 0.0623 |
Schistosoma mansoni | alcohol dehydrogenase | 0.0257 | 0.0295 | 0.1833 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0417 | 0.0502 | 0.044 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.127 | 0.1597 | 0.186 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0257 | 0.0295 | 0.0295 |
Mycobacterium tuberculosis | Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) | 0.0257 | 0.0295 | 0.0173 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1224 | 0.1538 | 0.1727 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.4371 | 0.558 | 0.6998 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0207 | 0.0232 | 0.1469 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.1404 | 0.177 | 0.2084 |
Mycobacterium ulcerans | polyketide synthase | 0.4115 | 0.525 | 0.6567 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.6158 | 0.7874 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0107 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0295 | 0.0322 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.2679 | 0.3407 | 0.6097 |
Brugia malayi | Phosphopantetheine attachment site family protein | 0.0417 | 0.0502 | 0.0502 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0372 | 0.0443 | 0.0489 |
Echinococcus granulosus | neuroligin | 0.0207 | 0.0232 | 0.1446 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0041 | 0.0019 | 0.0127 |
Trypanosoma brucei | Acyl carrier protein, mitochondrial | 0.0417 | 0.0502 | 0.3816 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0019 | 0.0105 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.0257 | 0.0295 | 0.2264 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.4371 | 0.558 | 0.6998 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.1009 | 0.1262 | 0.1426 |
Toxoplasma gondii | quinone oxidoreductase, putative | 0.0257 | 0.0295 | 0.0511 |
Leishmania major | acyl carrier protein, putative | 0.0417 | 0.0502 | 0.3199 |
Mycobacterium ulcerans | malonyl CoA-acyl carrier protein transacylase FabD | 0.0261 | 0.0301 | 0.009 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0257 | 0.0295 | 0.0295 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.1037 | 0.1297 | 0.8422 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0207 | 0.0232 | 0.1446 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0261 | 0.0301 | 0.1868 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0041 | 0.0019 | 0.0062 |
Mycobacterium tuberculosis | Meromycolate extension acyl carrier protein AcpM | 0.0417 | 0.0502 | 0.044 |
Echinococcus granulosus | acetylcholinesterase | 0.1224 | 0.1538 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0035 | 0.0012 | 0.0001 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0207 | 0.0232 | 0.009 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0338 | 0.0401 | 0.2552 |
Onchocerca volvulus | 0.0257 | 0.0295 | 0.0069 | |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.011 | 0.0107 | 0.0107 |
Schistosoma mansoni | methyltransferase-related | 0.1244 | 0.1564 | 1 |
Plasmodium vivax | malonyl CoA-acyl carrier protein transacylase precursor, putative | 0.0261 | 0.0301 | 0.2255 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.3362 | 0.4284 | 0.5345 |
Echinococcus granulosus | acyl carrier protein mitochondrial | 0.0417 | 0.0502 | 0.3214 |
Trypanosoma brucei | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2213 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0023 | 0.0079 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.1037 | 0.1297 | 0.8284 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0203 | 0.0227 | 0.1393 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.3866 | 0.4932 | 0.5562 |
Echinococcus granulosus | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0257 | 0.0295 | 0.1864 |
Loa Loa (eye worm) | phosphopantetheine attachment site family protein | 0.0417 | 0.0502 | 0.0555 |
Echinococcus granulosus | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.1037 | 0.1297 | 0.1394 |
Loa Loa (eye worm) | hypothetical protein | 0.0634 | 0.078 | 0.0869 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0257 | 0.0295 | 0.0295 |
Leishmania major | oxidoreductase-like protein | 0.0257 | 0.0295 | 0.1878 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.1037 | 0.1297 | 0.1394 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.1037 | 0.1297 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0019 | 0.0009 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.3308 | 0.4214 | 0.5171 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1244 | 0.1564 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase FadB5 | 0.0257 | 0.0295 | 0.0173 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.6158 | 0.7874 | 1 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.0257 | 0.0295 | 0.2264 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0019 | 0.0019 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.1037 | 0.1297 | 0.1394 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0112 | 0.0109 | 0.0635 |
Echinococcus multilocularis | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0025 | 0.0016 |
Mycobacterium ulcerans | fatty-acid-CoA ligase FadD9 | 0.0418 | 0.0503 | 0.0355 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.4004 | 0.5108 | 0.6413 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Toxoplasma gondii | hypothetical protein | 0.011 | 0.0107 | 0.0174 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.2348 | 0.2982 | 0.3656 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0207 | 0.0232 | 0.1446 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.3442 | 0.4386 | 0.5398 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.3866 | 0.4932 | 0.6185 |
Echinococcus granulosus | AMP dependent ligase | 0.0418 | 0.0503 | 0.3223 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase AdhE2 | 0.0257 | 0.0295 | 0.0083 |
Plasmodium vivax | hypothetical protein, conserved | 0.0592 | 0.0726 | 0.5561 |
Leishmania major | NADP-dependent alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.1878 |
Schistosoma mansoni | carbonic anhydrase-related | 0.011 | 0.0107 | 0.0623 |
Echinococcus granulosus | carboxylesterase 5A | 0.1224 | 0.1538 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0207 | 0.0232 | 0.1446 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0104 | 0.0105 |
Brugia malayi | Carboxylesterase family protein | 0.0207 | 0.0232 | 0.0232 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0418 | 0.0503 | 0.9403 |
Brugia malayi | hypothetical protein | 0.0207 | 0.0232 | 0.0232 |
Giardia lamblia | Methyltransferase like 2 | 0.1244 | 0.1564 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1224 | 0.1538 | 1 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.1037 | 0.1297 | 0.8293 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0107 | 0.0104 | 0.0609 |
Loa Loa (eye worm) | fatty acid synthase | 0.4075 | 0.52 | 0.5865 |
Leishmania major | carbonic anhydrase-like protein | 0.0203 | 0.0227 | 0.144 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0418 | 0.0503 | 0.0442 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0425 | 0.0512 | 0.0512 |
Mycobacterium tuberculosis | Possible dehydrogenase | 0.0257 | 0.0295 | 0.0173 |
Trypanosoma brucei | acyl transferase-like protein | 0.0261 | 0.0301 | 0.2255 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0338 | 0.0401 | 0.2552 |
Loa Loa (eye worm) | carboxylesterase | 0.0207 | 0.0232 | 0.025 |
Echinococcus multilocularis | Malonyl coenzyme A acyl carrier protein transacylase | 0.0261 | 0.0301 | 0.1899 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.1037 | 0.1297 | 0.8422 |
Mycobacterium tuberculosis | Hypothetical protein | 0.1244 | 0.1564 | 0.1818 |
Plasmodium falciparum | malonyl CoA-acyl carrier protein transacylase | 0.0261 | 0.0301 | 0.2255 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0023 | 0.0079 |
Leishmania major | hypothetical protein, conserved | 0.0261 | 0.0301 | 0.1912 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.011 | 0.0107 | 0.0107 |
Trypanosoma cruzi | acyl transferase-like protein, putative | 0.0261 | 0.0301 | 0.2305 |
Loa Loa (eye worm) | hypothetical protein | 0.6924 | 0.8858 | 1 |
Mycobacterium leprae | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0418 | 0.0503 | 0.0274 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.4115 | 0.525 | 0.6567 |
Mycobacterium ulcerans | hypothetical protein | 0.0417 | 0.0502 | 0.0353 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0257 | 0.0295 | 0.2264 |
Echinococcus multilocularis | snurportin 1 | 0.0372 | 0.0443 | 0.2832 |
Mycobacterium ulcerans | zinc-type alcohol dehydrogenase AdhD | 0.0257 | 0.0295 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.1224 | 0.1538 | 0.1727 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.4115 | 0.525 | 0.6567 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.4371 | 0.558 | 0.7025 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0112 | 0.0109 | 0.0646 |
Mycobacterium ulcerans | polyketide synthase | 0.4371 | 0.558 | 0.6998 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.1878 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0112 | 0.0109 | 0.0111 |
Leishmania major | zinc binding dehydrogenase-like protein | 0.0257 | 0.0295 | 0.1878 |
Brugia malayi | Carboxylesterase family protein | 0.1224 | 0.1538 | 0.1538 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.6158 | 0.7874 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0417 | 0.0502 | 0.3162 |
Mycobacterium tuberculosis | Possible dehydrogenase | 0.0257 | 0.0295 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.2299 | 0.2918 | 0.3286 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0257 | 0.0295 | 0.0173 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.1037 | 0.1297 | 1 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.1037 | 0.1297 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0443 | 0.0535 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Echinococcus granulosus | snurportin 1 | 0.0372 | 0.0443 | 0.2832 |
Loa Loa (eye worm) | acyl carrier protein | 0.0417 | 0.0502 | 0.0555 |
Echinococcus multilocularis | neuroligin | 0.0207 | 0.0232 | 0.1446 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0425 | 0.0512 | 0.0453 |
Loa Loa (eye worm) | hypothetical protein | 0.0634 | 0.078 | 0.0869 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.4004 | 0.5108 | 0.6413 |
Echinococcus multilocularis | Acyl carrier protein, mitochondrial | 0.0417 | 0.0502 | 0.3214 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0203 | 0.0227 | 0.1417 |
Onchocerca volvulus | 0.0257 | 0.0295 | 0.0069 | |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.4115 | 0.525 | 0.6598 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0257 | 0.0295 | 0.2264 |
Brugia malayi | Alcohol dehydrogenase class III | 0.0257 | 0.0295 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Echinococcus granulosus | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0112 | 0.0109 | 0.0635 |
Toxoplasma gondii | type I fatty acid synthase | 0.0634 | 0.078 | 0.138 |
Leishmania major | zinc-binding dehydrogenase-like protein | 0.0257 | 0.0295 | 0.1878 |
Treponema pallidum | acyl carrier protein | 0.0417 | 0.0502 | 0.5 |
Schistosoma mansoni | acetylcholinesterase | 0.0207 | 0.0232 | 0.1423 |
Echinococcus granulosus | NADH dehydrogenase | 0.0417 | 0.0502 | 0.3214 |
Echinococcus granulosus | geminin | 0.0205 | 0.0229 | 0.1428 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.5504 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.011 | 0.0107 | 0.0107 |
Mycobacterium ulcerans | oxidoreductase FadB5 | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0425 | 0.0512 | 0.0366 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.7445 | 0.9528 | 1 |
Loa Loa (eye worm) | alcohol dehydrogenase class III | 0.0257 | 0.0295 | 0.0322 |
Mycobacterium ulcerans | Zn-dependent alcohol dehydrogenase, AdhX | 0.0257 | 0.0295 | 0.0083 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0041 | 0.0019 | 0.0127 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.4115 | 0.525 | 0.6598 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.011 | 0.0107 | 0.0107 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.5504 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0112 | 0.0109 | 0.0109 |
Mycobacterium ulcerans | NADP-dependent oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Wolbachia endosymbiont of Brugia malayi | ACP S-malonyltransferase | 0.0261 | 0.0301 | 0.0053 |
Mycobacterium tuberculosis | Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) | 0.0257 | 0.0295 | 0.0173 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.4115 | 0.525 | 0.6567 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0207 | 0.0232 | 0.009 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0425 | 0.0512 | 0.0366 |
Onchocerca volvulus | 0.3866 | 0.4932 | 0.5056 | |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.0301 | 0.0328 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0592 | 0.0726 | 0.5561 |
Leishmania major | oxidoreductase, putative | 0.0257 | 0.0295 | 0.1878 |
Toxoplasma gondii | acyl transferase domain-containing protein | 0.0261 | 0.0301 | 0.0521 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0203 | 0.0227 | 0.1682 |
Mycobacterium leprae | conserved hypothetical protein | 0.0417 | 0.0502 | 0.0272 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.0229 | 0.1404 |
Brugia malayi | Methyltransferase-like protein 4 | 0.1244 | 0.1564 | 0.1564 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0023 | 0.0079 |
Echinococcus multilocularis | acetylcholinesterase | 0.1224 | 0.1538 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 35.4813 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.