Detailed information for compound 159567

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 353.254 | Formula: C16H21BrN2O2
  • H donors: 1 H acceptors: 1 LogP: 2.63 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C1C2CC[C@H](N2C)C[C@@H]1c1ccc(c(c1)Br)N
  • InChi: 1S/C16H21BrN2O2/c1-19-10-4-6-14(19)15(16(20)21-2)11(8-10)9-3-5-13(18)12(17)7-9/h3,5,7,10-11,14-15H,4,6,8,18H2,1-2H3/t10?,11-,14?,15?/m1/s1
  • InChiKey: LDJPMOIHMAEPSX-HYMRGOADSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0005 0.0005
Schistosoma mansoni inositol monophosphatase 0.0108 0.0071 0.0068
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.001 0.014
Entamoeba histolytica hypothetical protein 0.0107 0.007 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.0525 0.0381 1
Leishmania major phosphatidylinositol kinase related protein, putative 0.002 0.0006 0.0001
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0027 0.0011 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Schistosoma mansoni hypothetical protein 0.0309 0.0221 0.0217
Plasmodium vivax importin-beta 2, putative 0.0029 0.0012 0.0205
Echinococcus multilocularis microtubule associated protein 2 0.2154 0.1591 0.159
Brugia malayi MH2 domain containing protein 0.0017 0.0003 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.0131 0.0128
Leishmania major hypothetical protein, conserved 0.0182 0.0126 0.3221
Loa Loa (eye worm) hypothetical protein 0.0204 0.0143 0.0143
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0011 0.0236
Onchocerca volvulus 0.0182 0.0126 0.3238
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.002 0.0407
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.001 0.014
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0019 0.0005 0.0004
Onchocerca volvulus 0.0182 0.0126 0.3238
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Entamoeba histolytica hypothetical protein 0.0107 0.007 0.0065
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0525 0.0381 1
Entamoeba histolytica Ran family GTPase 0.0021 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Mycobacterium tuberculosis Conserved protein 0.0182 0.0126 0.0107
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0012 0.0323
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0191 0.503
Brugia malayi hypothetical protein 0.0017 0.0003 0.0027
Trichomonas vaginalis D-aminoacylase, putative 0.0182 0.0126 0.3319
Echinococcus granulosus neuropeptide s receptor 0.0959 0.0703 0.0703
Echinococcus multilocularis beta LACTamase domain containing family member 0.0182 0.0126 0.0125
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0012 0.0323
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0005 0.0004
Onchocerca volvulus 0.0028 0.0012 0.0192
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0039 0.0038
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0018 0.0017
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0018 0.0431
Brugia malayi hypothetical protein 0.0019 0.0005 0.0067
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0018 0.0482
Echinococcus multilocularis lamin 0.0028 0.0012 0.0011
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0182 0.0126 0.3283
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Schistosoma mansoni hypothetical protein 0.0065 0.0039 0.0035
Mycobacterium tuberculosis Probable hydrolase 0.0182 0.0126 0.0107
Echinococcus multilocularis Smad4 0.0017 0.0003 0.0002
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0525 0.0381 0.038
Trichomonas vaginalis D-aminoacylase, putative 0.0182 0.0126 0.3319
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.002 0.0005 0.0144
Loa Loa (eye worm) hypothetical protein 0.0182 0.0126 0.0126
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.003 0.074
Mycobacterium ulcerans hypothetical protein 1.347 1 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.002 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0178 0.0123 0.3202
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0525 0.0381 0.038
Trichomonas vaginalis diacylglycerol kinase, putative 0.0525 0.0381 1
Loa Loa (eye worm) hypothetical protein 0.0109 0.0072 0.0072
Onchocerca volvulus 0.0109 0.0072 0.1796
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.027 0.0191 0.4957
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.002 0.002
Onchocerca volvulus 0.002 0.0005 0.0018
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.027 0.0191 0.4957
Toxoplasma gondii hypothetical protein 0.0019 0.0005 0.012
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0108 0.0071 0.1871
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0005 0.0067
Loa Loa (eye worm) hypothetical protein 0.0182 0.0126 0.0126
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.002 0.0522
Echinococcus granulosus lamin dm0 0.0028 0.0012 0.0011
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0018 0.0343
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0005 0.0004
Schistosoma mansoni lipoxygenase 0.002 0.0005 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0011 0.0288
Echinococcus granulosus mitogen activated protein kinase 3 0.027 0.0191 0.0191
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.001 0.0116
Loa Loa (eye worm) ceramide kinase 0.0525 0.0381 0.0381
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0182 0.0126 0.0123
Echinococcus multilocularis sphingosine kinase 1 1.347 1 1
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0095 0.2445
Trichomonas vaginalis esterase, putative 0.0182 0.0126 0.3319
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0005 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0019 0.0005 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Echinococcus granulosus geminin 0.0186 0.0129 0.0128
Entamoeba histolytica hypothetical protein 0.0024 0.0008 0.0003
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.0005 0.0144
Plasmodium vivax diacylglycerol kinase, putative 0.0525 0.0381 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.0005 0.0005
Echinococcus multilocularis Diacylglycerol kinase theta 0.0525 0.0381 0.038
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0018 0.0482
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0007 0.006
Loa Loa (eye worm) hypothetical protein 0.0028 0.0011 0.0011
Echinococcus granulosus mitogen activated protein kinase 0.027 0.0191 0.0191
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0108 0.0071 0.1871
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.002 0.0019
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0039 0.0038
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0005 0.0001
Schistosoma mansoni lamin 0.0028 0.0012 0.0008
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0005 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0173 0.012 0.3143
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0005 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0191 0.0188
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0008 0.0216
Schistosoma mansoni lipoxygenase 0.0055 0.0031 0.0028
Plasmodium falciparum diacylglycerol kinase, putative 0.0525 0.0381 1
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0039 0.0038
Trichomonas vaginalis bmru protein, putative 0.0525 0.0381 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0002 0.0002
Trypanosoma brucei protein kinase, putative 0.027 0.0191 0.503
Schistosoma mansoni diacylglycerol kinase theta 0.0525 0.0381 0.0377
Echinococcus granulosus inositol monophosphatase 1 0.0108 0.0071 0.007
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0182 0.0126 0.0123
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0005 0.0091
Giardia lamblia Kinase, CMGC MAPK 0.027 0.0191 1
Echinococcus multilocularis survival motor neuron protein 1 0.0259 0.0183 0.0182
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0018 0.0017
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0005 0.0004
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0036 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0039 0.0039
Treponema pallidum sodium- and chloride- dependent transporter 0.0109 0.0072 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0189 0.0131 0.0131
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.027 0.0191 0.503
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0525 0.0381 1
Echinococcus granulosus ceramide kinase 0.0525 0.0381 0.038
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Trichomonas vaginalis inositol monophosphatase, putative 0.0108 0.0071 0.1871
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0108 0.0071 0.0066
Brugia malayi hypothetical protein 0.0525 0.0381 1
Brugia malayi Ceramide kinase 0.0525 0.0381 1
Echinococcus multilocularis mitogen activated protein kinase 0.027 0.0191 0.0191
Plasmodium falciparum diacylglycerol kinase, putative 0.0525 0.0381 1
Plasmodium falciparum importin beta, putative 0.0029 0.0012 0.0205
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.002 0.0383
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0525 0.0381 1
Brugia malayi MH2 domain containing protein 0.0017 0.0003 0.0035
Loa Loa (eye worm) hypothetical protein 0.0259 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0178 0.0123 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Echinococcus granulosus microtubule associated protein 2 0.2154 0.1591 0.159
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0039 0.0039
Schistosoma mansoni importin beta-1 0.0029 0.0012 0.0009
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0109 0.0072 0.0072
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0036 0.0033
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0108 0.0071 0.1871
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0005 0.0091
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0039 0.0972
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0005 0.0005
Brugia malayi Smad1 0.0017 0.0003 0.0035
Onchocerca volvulus Ceramide kinase 1 homolog 0.0525 0.0381 1
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0036 0.0947
Brugia malayi Inositol-1 0.0108 0.0071 0.1828
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0525 0.0381 1
Brugia malayi beta-lactamase 0.0182 0.0126 0.3283
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0182 0.0126 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.0182 0.0126 0.3221
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0019 0.0005 0.5
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0005 0.0001
Entamoeba histolytica diacylglycerol kinase, putative 0.0525 0.0381 0.0375
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0182 0.0126 0.0107
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0005 0.012
Mycobacterium leprae conserved hypothetical protein 0.0182 0.0126 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0005 0.0001
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.0005 0.0002
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.0005 0.0005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0231 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0005
Brugia malayi intermediate filament protein 0.0028 0.0012 0.0258
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0005 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0191 0.503
Schistosoma mansoni ran 0.0021 0.0007 0.0003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0018 0.0013
Brugia malayi TAR-binding protein 0.0064 0.0039 0.0967
Echinococcus granulosus importin subunit beta 1 0.0029 0.0012 0.0011
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0005 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Toxoplasma gondii ABC1 family protein 0.0182 0.0126 0.3319
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0018 0.0343
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0525 0.0381 0.038
Loa Loa (eye worm) hypothetical protein 0.014 0.0095 0.0095
Leishmania major diacylglycerol kinase-like protein 0.0525 0.0381 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.0131 0.0128
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0039 0.0035
Brugia malayi Calcitonin receptor-like protein seb-1 0.0204 0.0143 0.3715
Schistosoma mansoni hypothetical protein 0.0107 0.007 0.0067
Echinococcus multilocularis mitogen activated protein kinase 3 0.027 0.0191 0.0191
Trypanosoma cruzi hypothetical protein, conserved 0.0182 0.0126 0.3221
Entamoeba histolytica hypothetical protein 0.0027 0.0011 0.0006
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0012 0.0012
Mycobacterium ulcerans hypothetical protein 0.0182 0.0126 0.0107
Trichomonas vaginalis sphingosine kinase, putative 0.0525 0.0381 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.0126 0.0126
Mycobacterium leprae Probable lipase LipE 0.0182 0.0126 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.0131 0.013
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0027 0.0011 0.0288
Leishmania major hypothetical protein, conserved 0.0525 0.0381 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0109 0.0072 0.1851
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0031 0.003
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0525 0.0381 0.0377
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.002 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Trypanosoma cruzi Sphingosine kinase 0.0525 0.0381 1
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0039 0.0035
Brugia malayi RNA binding protein 0.0064 0.0039 0.0967
Loa Loa (eye worm) hypothetical protein 0.0525 0.0381 0.0381
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0019 0.0005 0.0004
Schistosoma mansoni hypothetical protein 0.0053 0.003 0.0027
Loa Loa (eye worm) hypothetical protein 1.347 1 1
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.001 0.014
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0007 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0005 0.0004
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0003 0.0002
Brugia malayi beta-lactamase family protein 0.0182 0.0126 0.3283
Brugia malayi Eye-specific diacylglycerol kinase 0.0525 0.0381 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0003 0.0002
Schistosoma mansoni survival motor neuron protein 0.0053 0.003 0.0027
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0525 0.0381 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0525 0.0381 1
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0019 0.0005 0.0004
Mycobacterium tuberculosis Diacylglycerol kinase 0.0525 0.0381 0.0361
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0182 0.0126 0.0107
Trypanosoma brucei diacylglycerol kinase, putative 0.0525 0.0381 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0204 0.0143 0.0143
Loa Loa (eye worm) diacylglycerol kinase 2 0.0525 0.0381 0.0381
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0031 0.003
Schistosoma mansoni hypothetical protein 0.002 0.0005 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.001 0.0116
Loa Loa (eye worm) hypothetical protein 0.0525 0.0381 0.0381
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0108 0.0071 0.1871
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0005 0.0002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.0131 0.013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.0131 0.013
Loa Loa (eye worm) hypothetical protein 0.0109 0.0072 0.0072
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.002 0.0522
Mycobacterium ulcerans beta-lactamase 0.0182 0.0126 0.0107
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Trypanosoma cruzi diacylglycerol kinase, putative 0.0525 0.0381 1
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.001 0.0258
Trichomonas vaginalis sphingosine kinase, putative 0.0525 0.0381 1
Echinococcus multilocularis snurportin 1 0.0309 0.0221 0.022
Echinococcus multilocularis serotonin transporter 0.0109 0.0072 0.0071
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0036 0.0035
Brugia malayi hypothetical protein 0.0107 0.007 0.1807
Mycobacterium ulcerans esterase/lipase LipP 0.0182 0.0126 0.0107
Echinococcus granulosus smad 0.0017 0.0003 0.0002
Echinococcus granulosus Diacylglycerol kinase zeta 0.0525 0.0381 0.038
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Echinococcus granulosus serotonin transporter 0.0109 0.0072 0.0071
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0036 0.0035
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0036 0.0016
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.007 0.007
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.0008 0.0071
Brugia malayi hypothetical protein 0.0026 0.001 0.0206
Schistosoma mansoni loxhd1 0.002 0.0005 0.0002
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0003 0.0002
Leishmania major GTP-binding protein, putative 0.0021 0.0007 0.003
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0012 0.0323
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.0005 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0036 0.0016
Echinococcus granulosus neuropeptide receptor A26 0.0959 0.0703 0.0703
Brugia malayi MH1 domain containing protein 0.0017 0.0003 0.0035
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.0005 0.0004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0005 0.0067
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.027 0.0191 0.0191
Echinococcus granulosus serine protein kinase ATM 0.0027 0.0011 0.001
Trichomonas vaginalis bmru protein, putative 0.0525 0.0381 1
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0012 0.0011
Echinococcus granulosus tar DNA binding protein 0.0064 0.0039 0.0038
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.0005 0.0005
Brugia malayi Doublecortin family protein 0.002 0.0005 0.0085
Brugia malayi diacylglycerol kinase 0.0525 0.0381 1
Toxoplasma gondii diacylglycerol kinase, putative 0.0525 0.0381 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0012
Brugia malayi Diacylglycerol kinase protein 2 0.0525 0.0381 1
Schistosoma mansoni hypothetical protein 0.0186 0.0129 0.0125
Toxoplasma gondii hypothetical protein 0.0019 0.0005 0.012
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.027 0.0191 0.503
Trichomonas vaginalis D-aminoacylase, putative 0.0182 0.0126 0.3319
Echinococcus multilocularis ceramide kinase 0.0525 0.0381 0.038
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1166 0.0857 0.0839
Echinococcus multilocularis musashi 0.0028 0.0012 0.0011
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0007 0.0006
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0005 0.0001
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0525 0.0381 0.0377
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0036 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Echinococcus multilocularis geminin 0.0186 0.0129 0.0128
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0037 0.0018 0.0018
Brugia malayi MH1 domain containing protein 0.0017 0.0003 0.0035
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.0005 0.0144
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.002 0.0383
Brugia malayi beta-lactamase family protein 0.0182 0.0126 0.3283
Schistosoma mansoni microtubule-associated protein tau 0.2154 0.1591 0.1588
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.0005 0.0004
Echinococcus granulosus intermediate filament protein 0.0028 0.0012 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0008 0.0216
Toxoplasma gondii target of rapamycin (TOR), putative 0.002 0.0005 0.0144
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0018 0.0015
Echinococcus multilocularis RUN 0.002 0.0005 0.0004
Schistosoma mansoni sodium/chloride dependent transporter 0.0109 0.0072 0.0069
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.001
Entamoeba histolytica hypothetical protein 0.0107 0.007 0.0065
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0005 0.012
Schistosoma mansoni lamin 0.0028 0.0012 0.0008
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0108 0.0071 0.1753
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0005 0.0004
Leishmania major sphingosine kinase A, B, putative 0.0525 0.0381 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.027 0.0191 0.4957
Entamoeba histolytica diacylglycerol kinase, putative 0.0525 0.0381 0.0375
Plasmodium vivax diacylglycerol kinase, putative 0.0525 0.0381 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.0126 0.0126
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0007 0.003
Trypanosoma cruzi Sphingosine kinase 0.0525 0.0381 1
Loa Loa (eye worm) inositol-1 0.0108 0.0071 0.0071
Schistosoma mansoni sodium-dependent amino acid transporter 0.0019 0.0005 0.0001
Schistosoma mansoni rab6-interacting 0.002 0.0005 0.0002
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0182 0.0126 0.0126
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0097 0.0063 0.0043
Leishmania major hypothetical protein, conserved 0.0026 0.001 0.0116
Trichomonas vaginalis penicillin-binding protein, putative 0.0182 0.0126 0.3319
Entamoeba histolytica diacylglycerol kinase, putative 0.0525 0.0381 0.0375
Loa Loa (eye worm) Smad1 0.0017 0.0003 0.0003
Trichomonas vaginalis penicillin-binding protein, putative 0.0182 0.0126 0.3319
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable lipase LipE 0.0182 0.0126 0.0107
Schistosoma mansoni intermediate filament proteins 0.0028 0.0012 0.0008
Echinococcus granulosus survival motor neuron protein 1 0.0259 0.0183 0.0182
Schistosoma mansoni polycystin 1-related 0.002 0.0005 0.0002
Echinococcus multilocularis lamin dm0 0.0028 0.0012 0.0011
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.002 0.0471
Schistosoma mansoni ap endonuclease 0.0039 0.002 0.0016
Trichomonas vaginalis diacylglycerol kinase, putative 0.0525 0.0381 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0018 0.0017
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0007 0.0173
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.007 0.0067
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.002 0.0773
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0005 0.0067
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0039 0.0967
Echinococcus multilocularis smad 0.0017 0.0003 0.0002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.027 0.0191 0.4957
Leishmania major hypothetical protein, conserved 0.0525 0.0381 1
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.0176 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0525 0.0381 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0007 0.0121
Schistosoma mansoni sphingoid long chain base kinase 1.347 1 1
Leishmania major diacylglycerol kinase, putative 0.0525 0.0381 1
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0525 0.0381 0.0381
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.002 0.0383
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0182 0.0126 0.0107
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0018 0.0017
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0007 0.0054
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.0131 0.013
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0108 0.0071 0.1753
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0182 0.0126 0.0107
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0065 0.0039 0.0035
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0039 0.0035
Onchocerca volvulus 0.0053 0.003 0.0677
Trypanosoma brucei hypothetical protein, conserved 0.0525 0.0381 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0005 0.012
Brugia malayi Importin beta-1 subunit 0.0029 0.0012 0.0271
Brugia malayi hypothetical protein 0.002 0.0005 0.0085
Mycobacterium ulcerans diacylglycerol kinase 0.0525 0.0381 0.0361
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0005 0.0004
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0039 0.0972
Mycobacterium tuberculosis Probable esterase LipL 0.0182 0.0126 0.0107
Brugia malayi diacylglycerol kinase 0.0525 0.0381 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0186 0.0129 0.0125
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Brugia malayi MH2 domain containing protein 0.0249 0.0176 0.4594
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0039 0.0038
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0191 0.503
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0525 0.0381 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0007 0.0173
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0007 0.003
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0011 0.0147
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Mycobacterium tuberculosis Conserved protein 0.0182 0.0126 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0039 0.0035
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.027 0.0191 0.4957
Echinococcus granulosus snurportin 1 0.0309 0.0221 0.022
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0018 0.0482
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0108 0.0071 0.1753
Echinococcus multilocularis GPCR, family 2 0.0065 0.0039 0.0038
Echinococcus multilocularis neuropeptide receptor A26 0.0959 0.0703 0.0703
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0012 0.0012
Trichomonas vaginalis ran, putative 0.0021 0.0007 0.0173
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0019 0.0005 0.0004
Echinococcus granulosus Smad4 0.0017 0.0003 0.0002
Loa Loa (eye worm) norepinephrine transporter 0.0109 0.0072 0.0072
Schistosoma mansoni rab6-interacting 0.002 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0191 0.503
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.001 0.0258
Loa Loa (eye worm) serotonin transporter b 0.0109 0.0072 0.0072
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable lipase LipD 0.0182 0.0126 0.0107
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0008 0.0073
Entamoeba histolytica hypothetical protein 0.0107 0.007 0.0065
Toxoplasma gondii FATC domain-containing protein 0.0027 0.0011 0.0288
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.027 0.0191 0.4957
Schistosoma mansoni hypothetical protein 0.0065 0.0039 0.0035
Brugia malayi hypothetical protein 0.0259 0.0183 0.4789
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1586 0.117 0.1169
Schistosoma mansoni ran 0.0021 0.0007 0.0003
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0525 0.0381 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Echinococcus multilocularis serine protein kinase ATM 0.0027 0.0011 0.001
Loa Loa (eye worm) solute carrier family 6 member 4 0.0109 0.0072 0.0072
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0018 0.0017
Loa Loa (eye worm) RNA binding protein 0.0064 0.0039 0.0039
Schistosoma mansoni ap endonuclease 0.0039 0.002 0.0016
Brugia malayi RNA, U transporter 1 0.0082 0.0052 0.132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.002 0.0407
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.0005 0.0144
Echinococcus granulosus lamin 0.0028 0.0012 0.0011
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0007 0.0007
Echinococcus granulosus GPCR family 2 0.0065 0.0039 0.0038
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0525 0.0381 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0005 0.0001
Onchocerca volvulus 0.0182 0.0126 0.3238
Loa Loa (eye worm) hypothetical protein 0.0029 0.0012 0.0012
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0309 0.0221 0.0221
Trypanosoma brucei Sphingosine kinase 0.0525 0.0381 1
Schistosoma mansoni diacylglycerol kinase theta 0.0525 0.0381 0.0377
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0108 0.0071 1
Schistosoma mansoni hypothetical protein 0.014 0.0095 0.0091
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0018 0.0692
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0525 0.0381 0.0377
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.0006 0.0001
Brugia malayi hypothetical protein 0.002 0.0005 0.0085
Entamoeba histolytica diacylglycerol kinase, putative 0.0525 0.0381 0.0375
Brugia malayi MAP kinase sur-1 0.027 0.0191 0.5003
Mycobacterium tuberculosis Conserved protein 0.0182 0.0126 0.0107
Schistosoma mansoni sphingosine kinase A B 1.347 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Toxoplasma gondii exonuclease III APE 0.0039 0.002 0.0522
Loa Loa (eye worm) hypothetical protein 0.0525 0.0381 0.0381
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.0131 0.0128
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0019 0.0005 0.0004
Leishmania major importin beta-1 subunit, putative 0.0024 0.0008 0.0073
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Echinococcus granulosus Diacylglycerol kinase theta 0.0525 0.0381 0.038
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0003 0.0002
Mycobacterium ulcerans lipase LipD 0.0182 0.0126 0.0107
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0039 0.0039
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0204 0.0143 0.3715
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0189 0.0131 0.3403
Entamoeba histolytica hypothetical protein, conserved 1.347 1 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.002 0.0005 0.0144
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0039 0.0035
Onchocerca volvulus 0.002 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0109 0.0072 0.0069
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0182 0.0126 0.0126
Loa Loa (eye worm) doublecortin family protein 0.002 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0065 0.0039 0.0035
Loa Loa (eye worm) beta-lactamase 0.0182 0.0126 0.0126
Schistosoma mansoni inositol monophosphatase 0.0108 0.0071 0.0068
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0018 0.0017
Onchocerca volvulus 0.0028 0.0012 0.0192
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0005 0.0001
Echinococcus granulosus beta LACTamase domain containing family member 0.0182 0.0126 0.0125
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0036 0.0016
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0039 0.0038
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.002 0.0522
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Schistosoma mansoni sodium/chloride dependent transporter 0.0021 0.0006 0.0003
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0018 0.0015
Brugia malayi follicle stimulating hormone receptor 0.0231 0.0162 0.4231
Loa Loa (eye worm) hypothetical protein 0.0065 0.0039 0.0039
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0018 0.0343
Mycobacterium tuberculosis Conserved protein 1.347 1 1
Echinococcus multilocularis inositol monophosphatase 1 0.0108 0.0071 0.007
Echinococcus granulosus RUN 0.002 0.0005 0.0004
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0525 0.0381 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0008 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Echinococcus multilocularis neuropeptide s receptor 0.0959 0.0703 0.0703
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0005 0.0001
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0108 0.0071 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0018 0.0482
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0005 0.0144
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0036 0.0815
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0012 0.0258
Trypanosoma brucei hypothetical protein, conserved 0.0182 0.0126 0.3319
Trypanosoma cruzi diacylglycerol kinase, putative 0.0525 0.0381 1
Plasmodium vivax hypothetical protein, conserved 0.0182 0.0126 0.3238
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.0176 0.0176

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 3.91 nM Concentration required to inhibit 50% of radioligand binding ([3H]-WIN 35428) to the dopamine (DA) transporter in rat ChEMBL. 8071935

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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