Detailed information for compound 1615836

Basic information

Technical information
  • TDR Targets ID: 1615836
  • Name: bicyclo[3.3.1]non-3-en-9-ol
  • MW: 138.207 | Formula: C9H14O
  • H donors: 1 H acceptors: 1 LogP: 1.84 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC1C2CCCC1C=CC2
  • InChi: 1S/C9H14O/c10-9-7-3-1-4-8(9)6-2-5-7/h1,3,7-10H,2,4-6H2
  • InChiKey: PGLXEGLAJQKZSQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 9-bicyclo[3.3.1]non-3-enol
  • NCI60_007872
  • Bicyclo[3.3.1]non-2-en-9-ol, syn-
  • syn-9-Hydroxybicyclo[3.3.1]Non-2-ene
  • AIDS-132131
  • AIDS132131
  • Bicyclo[3.3.1]non-2-en-9-ol
  • NSC625471
  • Bicyclo[3.3.1]non-2-en-9-ol, anti-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0027 0.004 0.041
Echinococcus granulosus dro:myosuppressin receptor 0.0174 0.0421 0.041
Schistosoma mansoni cpg binding protein 0.003 0.0049 0.0038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0468 0.1183 0.1173
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0028 0.0042 0.0166
Schistosoma mansoni biogenic amine (5HT) receptor 0.0174 0.0421 0.041
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0056 0.0624
Leishmania major hypothetical protein, conserved 0.0047 0.0093 0.1145
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.002 0.0022 0.0037
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.002 0.0022 0.0037
Schistosoma mansoni importin beta-1 0.0028 0.0043 0.0032
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.002 0.0022 0.0011
Schistosoma mansoni biogenic amine receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.0227 0.0216
Echinococcus multilocularis fmrfamide receptor 0.0174 0.0421 0.041
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.042 0.0702
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0034 0.1052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0154 0.0369 0.075
Brugia malayi neuropeptide F receptor 0.0174 0.0421 0.0702
Leishmania major RNA-editing complex protein MP100, putative 0.0027 0.004 0.041
Onchocerca volvulus 0.0023 0.003 0.0154
Brugia malayi Serotonin receptor 0.0174 0.0421 0.0702
Mycobacterium tuberculosis Probable esterase LipL 0.0291 0.0724 0.1492
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.0738
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0038 0.0069 0.0122
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Giardia lamblia hypothetical protein 0.0027 0.004 0.0558
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0043 0.0032
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0039 0.0072 0.0061
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0022 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0135 0.0319 0.4314
Onchocerca volvulus Neuropeptide F receptor homolog 0.0174 0.0421 0.3385
Onchocerca volvulus 0.0174 0.0421 0.3385
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0028 0.0043 0.0446
Echinococcus granulosus geminin 0.1218 0.3126 0.3118
Mycobacterium tuberculosis Conserved protein 0.0027 0.004 0.0061
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.002 0.0022 0.0011
Brugia malayi jmjC domain containing protein 0.01 0.023 0.0383
Echinococcus multilocularis g-protein coupled receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0174 0.0421 0.0702
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0157 0.0378 0.5142
Brugia malayi neuropeptide F receptor 0.0174 0.0421 0.0702
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0027 0.004 0.0153
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0049 0.0038
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0028 0.0879
Entamoeba histolytica hypothetical protein 0.0113 0.0262 0.8137
Mycobacterium ulcerans polyketide synthase MbtD 0.0048 0.0095 0.1181
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0056 0.0045
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Schistosoma mansoni hypothetical protein 0.0174 0.0421 0.041
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0174 0.0421 0.0702
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0061
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0039 0.0072 0.012
Trypanosoma brucei polo-like protein kinase 0.0099 0.0227 0.3027
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.0724 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0174 0.0421 0.041
Leishmania major importin beta-1 subunit, putative 0.0023 0.0029 0.0256
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0174 0.0421 0.041
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0135 0.0319 0.4314
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0022 0.0037
Brugia malayi G-protein coupled receptor 0.0174 0.0421 0.0702
Schistosoma mansoni synaptojanin 0.0027 0.004 0.0029
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0172 0.0416 0.0405
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0291 0.0724 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Echinococcus granulosus neuropeptide receptor A26 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0067
Brugia malayi Dopamine receptor protein 1 0.0174 0.0421 0.0702
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0024 0.0013
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0174 0.0421 0.041
Schistosoma mansoni cpg binding protein 0.0029 0.0044 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0227 0.0216
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0022 0.0011
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0027 0.004 0.041
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.002 0.0022 0.0037
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.0724 0.5849
Echinococcus granulosus neuropeptide Y receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0054 0.011 0.0207
Schistosoma mansoni alpha-1 adrenergic receptor 0.0174 0.0421 0.041
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0033 0.0645
Loa Loa (eye worm) G protein alpha subunit 3 0.002 0.0022 0.0037
Echinococcus granulosus tm gpcr rhodopsin 0.0174 0.0421 0.041
Brugia malayi latrophilin 2 splice variant baaae 0.0174 0.042 0.0702
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0056
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0033 0.0312
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.041 0.1033 0.1724
Brugia malayi G-protein alpha subunit 0.002 0.0022 0.0037
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0291 0.0724 0.1492
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0056 0.0045
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.0227 0.0378
Schistosoma mansoni hypothetical protein 0.0174 0.0421 0.041
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0022 0.0011
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0022 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0033 0.0056
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0049 0.0098 0.0182
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.002 0.0022 0.0037
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0049 0.0535
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0167 0.0403 0.5498
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0174 0.0421 0.0702
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0127 0.0298 0.4025
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0174 0.0421 0.0702
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.0227 0.6991
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0024 0.0032 0.0045
Brugia malayi hypothetical protein 0.0113 0.0262 0.0437
Echinococcus granulosus somatostatin receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) neuropeptide F receptor 0.0174 0.0421 0.0702
Schistosoma mansoni hypothetical protein 0.008 0.0178 0.0168
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0135 0.0319 0.4314
Echinococcus granulosus cpg binding protein 0.003 0.0049 0.0038
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0262 0.0251
Giardia lamblia Kinase, PLK 0.0099 0.0227 0.6887
Echinococcus multilocularis serotonin receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Onchocerca volvulus Putative neutral sphingomyelinase 0.0027 0.004 0.0241
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0135 0.0319 0.4314
Loa Loa (eye worm) beta-lactamase 0.0291 0.0724 0.1208
Mycobacterium tuberculosis Probable hydrolase 0.0291 0.0724 0.1492
Onchocerca volvulus 0.0174 0.0421 0.3385
Brugia malayi RNA, U transporter 1 0.008 0.0178 0.0298
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0056
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.004 0.0153
Schistosoma mansoni biogenic amine (5HT) receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0023 0.003 0.0039
Schistosoma mansoni histamine h1 receptor 0.0174 0.0421 0.041
Echinococcus granulosus g protein coupled receptor 0.0174 0.0421 0.041
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0174 0.0421 0.041
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0056 0.0045
Mycobacterium tuberculosis Conserved protein 0.0291 0.0724 0.1492
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0135 0.0319 0.0644
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0152 0.0365 0.0741
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0174 0.0421 0.041
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0174 0.0421 0.0702
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0022 0.0011
Brugia malayi G protein-coupled receptor F59B2.13 0.0174 0.0421 0.0702
Brugia malayi sulfakinin receptor protein 0.0174 0.0421 0.0702
Mycobacterium ulcerans glutaminase 0.0269 0.0668 0.9214
Loa Loa (eye worm) acyl carrier protein 0.0072 0.0157 0.0263
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0056 0.0624
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0017 0.0532
Mycobacterium ulcerans lipase LipD 0.0291 0.0724 1
Onchocerca volvulus 0.0174 0.0421 0.3385
Loa Loa (eye worm) hypothetical protein 0.0088 0.0198 0.0331
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0022 0.0011
Trichomonas vaginalis ap endonuclease, putative 0.0135 0.0319 0.2472
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0023 0.003 0.0261
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.004 0.041
Leishmania major endonuclease/exonuclease protein-like protein 0.0027 0.004 0.041
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0172 0.0416 0.0405
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0152 0.0365 0.0741
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0174 0.0421 0.041
Schistosoma mansoni ap endonuclease 0.0135 0.0319 0.0308
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0027 0.004 0.0029
Schistosoma mansoni neutral sphingomyelinase 0.0027 0.004 0.0029
Entamoeba histolytica hypothetical protein 0.0113 0.0262 0.8137
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0017 0.1017
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0027 0.004 0.1255
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0235 0.0579 0.119
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.002 0.0022 0.0037
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0235 0.0579 0.119
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) acyl carrier protein 0.0016 0.0011 0.0018
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0262 0.0251
Echinococcus multilocularis neuropeptide FF receptor 2 0.0174 0.0421 0.041
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0034 0.0319
Toxoplasma gondii exonuclease III APE 0.0135 0.0319 0.4314
Entamoeba histolytica Ran family GTPase 0.0021 0.0024 0.0334
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0174 0.0421 0.041
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0027 0.004 0.041
Onchocerca volvulus 0.0027 0.004 0.0241
Loa Loa (eye worm) G-protein coupled receptor 0.0174 0.0421 0.0702
Onchocerca volvulus 0.0029 0.0044 0.0275
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0066 0.0055
Loa Loa (eye worm) neuropeptide F receptor 0.0174 0.0421 0.0702
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.01 0.023 0.0219
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0027 0.004 0.041
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.0752 0.1256
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0024 0.0179
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0023 0.003 0.0261
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0285 0.0475
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0298 0.0743 0.1239
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Leishmania major hypothetical protein, conserved 0.0025 0.0034 0.0319
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0027 0.004 0.0029
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0027 0.004 0.041
Brugia malayi Latrophilin receptor protein 2 0.008 0.0178 0.0298
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0056 0.0093
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0135 0.0319 0.4399
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0049 0.0082
Onchocerca volvulus 0.0174 0.0421 0.3385
Giardia lamblia PHD finger protein 15 0.0031 0.0049 0.086
Echinococcus granulosus g-protein coupled receptor 0.0174 0.0421 0.041
Brugia malayi MH2 domain containing protein 0.0121 0.0285 0.0475
Onchocerca volvulus 0.0174 0.0421 0.3385
Echinococcus granulosus neuropeptide FF receptor 2 0.0174 0.0421 0.041
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0174 0.0421 0.3385
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0049 0.0038
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.004 0.0552
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0097 0.0626
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0043 0.0451
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0129 0.0118
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0174 0.0421 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0017 0.0234
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Echinococcus multilocularis somatostatin receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0023 0.003 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Schistosoma mansoni glutaminase 0.0269 0.0668 0.0658
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0039 0.0072 0.012
Plasmodium vivax hypothetical protein, conserved 0.0027 0.004 0.0552
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0027 0.004 0.0873
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0022 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0291 0.0724 0.5849
Onchocerca volvulus 0.002 0.0022 0.009
Echinococcus multilocularis g protein coupled receptor 0.0174 0.0421 0.041
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.004 0.041
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0227 0.3027
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0174 0.0421 0.041
Echinococcus multilocularis g protein coupled receptor 0.0174 0.0421 0.041
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0101 0.0659
Echinococcus multilocularis cpg binding protein 0.003 0.0049 0.0038
Echinococcus granulosus neuropeptides capa receptor 0.0174 0.0421 0.041
Echinococcus granulosus g protein coupled receptor 0.0174 0.0421 0.041
Echinococcus multilocularis beta LACTamase domain containing family member 0.0291 0.0724 0.0714
Schistosoma mansoni neuropeptide f receptor 76f 0.0174 0.0421 0.041
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0039 0.0072 0.0858
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Treponema pallidum exodeoxyribonuclease (exoA) 0.0135 0.0319 1
Schistosoma mansoni ap endonuclease 0.0135 0.0319 0.0308
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0015 0.0008
Echinococcus multilocularis neutral sphingomyelinase 0.0027 0.004 0.0029
Echinococcus multilocularis citrate lyase subunit beta protein 0.0027 0.004 0.0029
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0056 0.0093
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0044 0.0074
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0033 0.0312
Brugia malayi G protein-coupled receptor 0.0174 0.0421 0.0702
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Mycobacterium ulcerans fatty acid synthase Fas 0.0049 0.0098 0.1219
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Plasmodium vivax exodeoxyribonuclease III, putative 0.0027 0.004 0.0552
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0128 0.1635
Trypanosoma brucei RNA editing exonuclease 2 0.0027 0.004 0.041
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0174 0.0421 0.041
Echinococcus granulosus hypothetical protein 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus importin subunit beta 1 0.0028 0.0043 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.007 0.0117
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium leprae Polyketide synthase Pks13 0.0235 0.0579 0.7972
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.0227 0.3027
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0101 0.1263
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0029 0.0256
Echinococcus multilocularis synaptojanin 1 0.0027 0.004 0.0029
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0033 0.0312
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Brugia malayi AMP-binding enzyme family protein 0.0154 0.0369 0.0617
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.004 0.0552
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0135 0.0319 1
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0022 0.0011
Schistosoma mansoni carbon catabolite repressor protein 0.0027 0.004 0.0029
Schistosoma mansoni cpg binding protein 0.003 0.0049 0.0038
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0167 0.0403 0.5498
Mycobacterium ulcerans polyketide synthase 0.0157 0.0378 0.5142
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.0227 0.0378
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0022 0.0011
Schistosoma mansoni kinase 0.005 0.01 0.009
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0468 0.1183 0.1974
Mycobacterium ulcerans thioesterase 0.0131 0.031 0.4189
Mycobacterium tuberculosis Hypothetical protein 0.0047 0.0093 0.0171
Echinococcus granulosus G protein coupled receptor 139 0.0174 0.0421 0.041
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0014 0.0036
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0024 0.0325
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0039 0.0072 0.0858
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Echinococcus multilocularis AMP dependent ligase 0.0017 0.0014 0.0003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0178 0.0298
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Echinococcus granulosus tm gpcr rhodopsin 0.0174 0.0421 0.041
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0178 0.0168
Brugia malayi Pre-SET motif family protein 0.0061 0.0129 0.0215
Trichomonas vaginalis ap endonuclease, putative 0.0135 0.0319 0.2472
Brugia malayi CXXC zinc finger family protein 0.0029 0.0044 0.0074
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0033 0.0312
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0024 0.0032 0.0045
Loa Loa (eye worm) hypothetical protein 0.008 0.0178 0.0298
Mycobacterium tuberculosis Conserved protein 0.0291 0.0724 0.1492
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0174 0.0421 0.041
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0034 0.0463
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0236 0.0583 0.0572
Echinococcus granulosus orexin receptor type 2 0.0174 0.0421 0.041
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0027 0.004 0.0153
Echinococcus granulosus tachykinin peptides receptor 99D 0.0174 0.0421 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Loa Loa (eye worm) hypothetical protein 0.0028 0.0043 0.0072
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0102 0.0234 0.3133
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0167 0.0403 0.5498
Schistosoma mansoni hypothetical protein 0.008 0.0178 0.0168
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0468 0.1183 0.1173
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0022 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0291 0.0724 1
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.0724 0.5849
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0027 0.004 0.0061
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0033 0.0047
Mycobacterium leprae Probable polyketide synthase Pks1 0.0167 0.0403 0.5498
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0027 0.004 0.1255
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0067
Echinococcus multilocularis fmrfamide receptor 0.0174 0.0421 0.041
Schistosoma mansoni biogenic amine receptor 0.0174 0.0421 0.041
Echinococcus multilocularis deoxyribonuclease 1 2 0.0027 0.004 0.0029
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0179
Brugia malayi Dopamine receptor protein 2 0.0174 0.0421 0.0702
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0129 0.0118
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0017 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.004 0.0074 0.1996
Entamoeba histolytica hypothetical protein 0.0113 0.0262 0.8137
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0027 0.004 0.0152
Schistosoma mansoni myosin xvIII 0.0174 0.0421 0.041
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0056 0.0624
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0129 0.0118
Onchocerca volvulus 0.002 0.0022 0.009
Mycobacterium tuberculosis Conserved protein 0.0291 0.0724 0.1492
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Onchocerca volvulus 0.0291 0.0724 0.5887
Brugia malayi follicle stimulating hormone receptor 0.0174 0.0421 0.0702
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0101 0.1392
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0024 0.0041
Plasmodium falciparum DNase I-like protein, putative 0.0027 0.004 0.1255
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0022 0.0011
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Leishmania major hypothetical protein, conserved 0.0027 0.004 0.041
Loa Loa (eye worm) melatonin receptor type 1A 0.0174 0.0421 0.0702
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0174 0.0421 0.0702
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0131 0.031 0.4189
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0033 0.0312
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.007 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0236 0.0581 0.7998
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Brugia malayi hypothetical protein 0.002 0.0022 0.0037
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0039 0.0072 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0039 0.0072 0.0993
Onchocerca volvulus 0.0174 0.0421 0.3385
Schistosoma mansoni synaptojanin 0.0027 0.004 0.0029
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1646 0.4237 0.4231
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.004 0.0153
Trypanosoma cruzi mitochondrial protein 99, putative 0.0027 0.004 0.041
Trypanosoma cruzi mitochondrial protein 99, putative 0.0027 0.004 0.041
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.007 0.0059
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0033 0.0312
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0098 0.0163
Plasmodium falciparum importin beta, putative 0.0028 0.0043 0.1346
Echinococcus granulosus traf and tnf receptor associated protein 0.0027 0.004 0.0029
Plasmodium vivax SET domain protein, putative 0.0061 0.0129 0.1779
Schistosoma mansoni hypothetical protein 0.0174 0.0421 0.041
Echinococcus multilocularis allatostatin A receptor 0.0174 0.0421 0.041
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0262 0.0251
Schistosoma mansoni hypothetical protein 0.1218 0.3126 0.3118
Leishmania major GTP-binding protein, putative 0.0021 0.0024 0.0179
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0291 0.0724 0.1208
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0027 0.004 0.0153
Leishmania major hypothetical protein, conserved 0.0236 0.0581 0.7998
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0015 0.0008
Loa Loa (eye worm) fatty acid synthase 0.0155 0.0372 0.0621
Schistosoma mansoni jumonji domain containing protein 0.008 0.0176 0.0165
Echinococcus granulosus GPCR family 2 0.008 0.0178 0.0168
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.0227 0.0216
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0135 0.0319 0.0532
Onchocerca volvulus 0.0174 0.0421 0.3385
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0028 0.0387
Echinococcus multilocularis GPCR, family 2 0.008 0.0178 0.0168
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0056 0.0624
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0178 0.0168
Echinococcus granulosus peregrin 0.0035 0.006 0.0049
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0178 0.0298
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0101 0.009
Schistosoma mansoni ran 0.0021 0.0024 0.0013
Mycobacterium ulcerans polyketide synthase MbtC 0.0039 0.0072 0.0858
Schistosoma mansoni hypothetical protein 0.0113 0.0262 0.0251
Trypanosoma cruzi hypothetical protein, conserved 0.0236 0.0581 0.7998
Brugia malayi Calcitonin receptor-like protein seb-1 0.0254 0.0629 0.105
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0043 0.0451
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.002 0.0009
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0135 0.0319 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0033 0.0645
Echinococcus multilocularis sex peptide receptor 0.0174 0.0421 0.041
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0174 0.0421 0.041
Echinococcus multilocularis neuropeptide receptor 0.0174 0.0421 0.041
Echinococcus multilocularis neuropeptide Y receptor 0.0174 0.0421 0.041
Echinococcus granulosus neuropeptide s receptor 0.0174 0.0421 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Brugia malayi beta-lactamase family protein 0.0291 0.0724 0.1208
Mycobacterium ulcerans esterase/lipase LipP 0.0291 0.0724 1
Brugia malayi ORL1-like opioid receptor 0.0174 0.0421 0.0702
Entamoeba histolytica G protein alpha subunit, putative 0.002 0.0022 0.0273
Mycobacterium ulcerans beta-lactamase 0.0291 0.0724 1
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 0.2323 0.5992 0.5987
Toxoplasma gondii ABC1 family protein 0.0291 0.0724 1
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0034 0.1052
Onchocerca volvulus 0.0174 0.0421 0.3385
Mycobacterium leprae Probable lipase LipE 0.0291 0.0724 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0106 0.0177
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Mycobacterium ulcerans Type I modular polyketide synthase 0.0157 0.0378 0.5142
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Mycobacterium ulcerans polyketide synthase Pks13 0.0235 0.0579 0.7972
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0468 0.1183 0.1173
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Brugia malayi Tachykinin-like peptides receptor 99D 0.0174 0.0421 0.0702
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0291 0.0724 0.1492
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.0227 0.1782
Loa Loa (eye worm) hypothetical protein 0.041 0.1033 0.1724
Echinococcus granulosus alpha 1A adrenergic receptor 0.0174 0.0421 0.041
Onchocerca volvulus Alhambra homolog 0.0031 0.0049 0.0315
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0027 0.004 0.1255
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0174 0.0421 0.041
Leishmania major pantothenate kinase subunit, putative 0.0028 0.0043 0.0446
Onchocerca volvulus 0.0174 0.0421 0.3385
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0104 0.0239 0.3205
Echinococcus granulosus jumonji domain containing protein 0.0043 0.008 0.0069
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0024 0.0032 0.03
Plasmodium falciparum phd finger protein, putative 0.0031 0.0049 0.1535
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0022 0.0011
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0027 0.004 0.0873
Schistosoma mansoni biogenic amine receptor 0.0174 0.0421 0.041
Schistosoma mansoni trimeric G-protein alpha o subunit 0.002 0.0022 0.0011
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1859 0.4787 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0056 0.0624
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0134 0.0123
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0227 0.3027
Loa Loa (eye worm) hypothetical protein 0.2323 0.5992 1
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.002 0.0022 0.0011
Echinococcus granulosus 7tm_1 domain containing protein 0.0174 0.0421 0.041
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0122 0.0111
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Onchocerca volvulus 0.0291 0.0724 0.5887
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0113 0.0263 0.0527
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0129 0.0303 0.0612
Leishmania major hypothetical protein, conserved 0.0027 0.004 0.041
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0017 0.0014 0.0036
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0022 0.0011
Loa Loa (eye worm) acetyltransferase 0.0172 0.0416 0.0694
Echinococcus multilocularis orexin receptor type 2 0.0174 0.0421 0.041
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Onchocerca volvulus 0.0291 0.0724 0.5887
Trichomonas vaginalis Phospholipase C precursor, putative 0.0027 0.004 0.0153
Entamoeba histolytica hypothetical protein 0.0113 0.0262 0.8137
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0054
Brugia malayi Importin beta-1 subunit 0.0028 0.0043 0.0072
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0056 0.0624
Echinococcus multilocularis snurportin 1 0.0302 0.0752 0.0742
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0167 0.0403 0.0821
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0056
Onchocerca volvulus 0.0024 0.0033 0.0184
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Brugia malayi hypothetical protein 0.0025 0.0034 0.0056
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0024 0.0032 0.0045
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Toxoplasma gondii type I fatty acid synthase, putative 0.0112 0.026 0.3494
Brugia malayi isocitrate dehydrogenase 0.0033 0.0056 0.0093
Schistosoma mansoni hypothetical protein 0.008 0.0178 0.0168
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0027 0.004 0.0029
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0129 0.0118
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0179
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.002 0.0022 0.0037
Echinococcus granulosus citrate lyase subunit beta protein 0.0027 0.004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi CCR4 0.0028 0.0042 0.007
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0265 0.0657 0.1097
Mycobacterium tuberculosis Probable thioesterase TesA 0.0131 0.031 0.0625
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0089 0.0202 0.0399
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0157 0.0378 0.063
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Loa Loa (eye worm) G-protein coupled receptor 0.0174 0.0421 0.0702
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0023 0.003 0.0039
Echinococcus granulosus neutral sphingomyelinase 0.0027 0.004 0.0029
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0039 0.0072 0.0858
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0048 0.0095 0.0176
Echinococcus granulosus fmrfamide receptor 0.0174 0.0421 0.041
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0101 0.1263
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0033 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0468 0.1183 0.1173
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0067
Schistosoma mansoni hypothetical protein 0.0302 0.0752 0.0742
Mycobacterium tuberculosis Probable exported protein 0.0027 0.004 0.0061
Onchocerca volvulus 0.002 0.0022 0.009
Echinococcus granulosus beta LACTamase domain containing family member 0.0291 0.0724 0.0714
Brugia malayi Melatonin receptor type 1A 0.0174 0.0421 0.0702
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0174 0.0421 0.041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.004 0.041
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0022 0.0011
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0135 0.0319 0.0308
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0101 0.0659
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0022 0.0011
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0039 0.0072 0.1989
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0027 0.004 0.041
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0174 0.0421 0.041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.004 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi putative neuropeptide receptor 0.0174 0.0421 0.0702
Schistosoma mansoni neuropeptide F-like receptor 0.0174 0.0421 0.041
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0056 0.0763
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0027 0.004 0.0029
Echinococcus granulosus neuropeptide receptor 0.0174 0.0421 0.041
Leishmania major hypothetical protein, conserved 0.0027 0.004 0.041
Echinococcus granulosus neuropeptides capa receptor 0.0174 0.0421 0.041
Giardia lamblia Inositol 5-phosphatase 4 0.0027 0.004 0.0558
Echinococcus multilocularis dro:myosuppressin receptor 0.0174 0.0421 0.041
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0033 0.0312
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0174 0.0421 0.041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.003 0.0049
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0027 0.004 0.041
Schistosoma mansoni growth hormone secretagogue receptor 0.0174 0.0421 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0039 0.0072 1
Schistosoma mansoni nocturnin 0.0027 0.004 0.0029
Brugia malayi GnHR receptor homolog 0.0174 0.0421 0.0702
Schistosoma mansoni adenoreceptor 0.0174 0.0421 0.041
Brugia malayi PHD-finger family protein 0.0031 0.0049 0.0082
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0027 0.004 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0056
Onchocerca volvulus 0.0281 0.0698 0.5675
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0033 0.0312
Brugia malayi beta-lactamase 0.0291 0.0724 0.1208
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0022 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis serotonin receptor 0.0174 0.0421 0.041
Trichomonas vaginalis set domain proteins, putative 0.0483 0.1222 1
Brugia malayi putative neuropeptide receptor NPR1 0.0174 0.0421 0.0702
Brugia malayi Pre-SET motif family protein 0.0424 0.107 0.1786
Loa Loa (eye worm) glutaminase 0.0269 0.0668 0.1115
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.002 0.0022 0.0037
Echinococcus multilocularis neuropeptide s receptor 0.0174 0.0421 0.041
Echinococcus granulosus AMP dependent ligase 0.0017 0.0014 0.0003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0291 0.0724 0.0714
Onchocerca volvulus 0.0174 0.0421 0.3385
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium ulcerans polyketide synthase 0.0167 0.0403 0.5498
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0034 0.0319
Brugia malayi glutaminase DH11.1 0.0269 0.0668 0.1115
Leishmania major hypothetical protein, conserved 0.0291 0.0724 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0034 0.0319
Mycobacterium ulcerans polyketide synthase Pks9 0.0104 0.0239 0.3205
Loa Loa (eye worm) TYRA-2 protein 0.0174 0.0421 0.0702
Trichomonas vaginalis glutaminase, putative 0.0269 0.0668 0.5383
Schistosoma mansoni opsin-like receptor 0.0174 0.0421 0.041
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0027 0.004 0.0029
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus allatostatin A receptor 0.0174 0.0421 0.041
Mycobacterium ulcerans hypothetical protein 0.0024 0.0033 0.0312
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0056 0.0045
Brugia malayi jmjC domain containing protein 0.0039 0.007 0.0117
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0016 0.0011 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.0724 0.5849
Schistosoma mansoni hypothetical protein 0.0174 0.042 0.041
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0022 0.0011
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Mycobacterium tuberculosis Conserved protein 0.0047 0.0093 0.0171
Echinococcus multilocularis neuropeptide receptor A26 0.0174 0.0421 0.041
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0174 0.0421 0.0702
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0157 0.0378 0.5142
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0093 0.0589
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.007 0.0059
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0135 0.0319 0.0308
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0167 0.0403 0.0821
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.01 0.023 0.0219
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0049 0.0675
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0157 0.0378 0.0768
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0135 0.0319 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0174 0.0421 0.041
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0034 0.0319
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0027 0.004 0.1255
Brugia malayi Methyltransferase-like protein 4 0.0047 0.0093 0.0155
Schistosoma mansoni hypothetical protein 0.008 0.0178 0.0168
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus alpha 16 mannosyl glycoprotein 0.2323 0.5992 0.5987
Onchocerca volvulus Fatty acid synthase homolog 0.0284 0.0705 0.573
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0104 0.0239 0.3205
Treponema pallidum hypothetical protein 0.0027 0.004 0.095
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0039 0.0072 0.0858
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.009 0.2508
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.002 0.0022 0.0037
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.004
Toxoplasma gondii type I fatty acid synthase 0.0024 0.0032 0.03
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.004 0.0873
Onchocerca volvulus 0.0483 0.1222 1
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0174 0.0421 0.041
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0016 0.0011 0.0018
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0023 0.003 0.0261
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0097 0.0626
Schistosoma mansoni neuropeptide receptor 0.0174 0.0421 0.041
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0027 0.004 0.0873
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0017 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Echinococcus granulosus serotonin receptor 0.0174 0.0421 0.041
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0056 0.0045
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0174 0.0421 0.041
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Brugia malayi Serotonin receptor 0.0174 0.0421 0.0702
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0174 0.0421 0.0702
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0129 0.1656
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0024 0.0032 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0179
Echinococcus multilocularis geminin 0.1218 0.3126 0.3118
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0039 0.0072 0.2259
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0027 0.004 0.041
Brugia malayi Dopamine receptor 0.0174 0.0421 0.0702
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0023 0.003 0.0261
Echinococcus multilocularis neuropeptide Y receptor 0.0174 0.0421 0.041
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0027 0.004 0.041
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.004 0.041
Echinococcus granulosus snurportin 1 0.0302 0.0752 0.0742
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0049 0.0098 0.1219
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 0.2323 0.5992 0.5987
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0056 0.0093
Brugia malayi exodeoxyribonuclease III family protein 0.0135 0.0319 0.0532
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0033 0.0056
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.004 0.041
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0135 0.0319 1
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0064 0.0135 0.0259
Trichomonas vaginalis penicillin-binding protein, putative 0.0291 0.0724 0.5849
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0033 0.0312
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.002 0.0022 0.0037
Toxoplasma gondii type I fatty acid synthase, putative 0.0168 0.0405 0.5534
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Mycobacterium ulcerans hypothetical protein 0.0027 0.004 0.041
Brugia malayi Bromodomain containing protein 0.0035 0.006 0.01
Echinococcus granulosus biogenic amine 5HT receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0015 0.0008
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0424 0.107 0.1786
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0129 0.0118
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0049 0.0038
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.004 0.041
Echinococcus granulosus 7TM GPCR rhodopsin 0.0174 0.0421 0.041
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0157 0.0378 0.0768
Schistosoma mansoni opsin-like receptor 0.0174 0.0421 0.041
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0157 0.0378 0.5142
Echinococcus multilocularis neuropeptides capa receptor 0.0174 0.0421 0.041
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.003 0.0261
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Loa Loa (eye worm) glutaminase 2 0.0269 0.0668 0.1115
Echinococcus multilocularis expressed protein 0.002 0.0022 0.0011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0468 0.1183 0.1173
Schistosoma mansoni hypothetical protein 0.1218 0.3126 0.3118
Echinococcus multilocularis traf and tnf receptor associated protein 0.0027 0.004 0.0029
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0236 0.0583 0.0572
Schistosoma mansoni hypothetical protein 0.0031 0.0049 0.0038
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0022 0.0037
Trypanosoma brucei hypothetical protein, conserved 0.0291 0.0724 1
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0056 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0067
Schistosoma mansoni opsin-like receptor 0.0174 0.0421 0.041
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0029 0.0061
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0129 0.0118
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi RE15519p 0.0174 0.0421 0.0702
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0291 0.0724 0.1208
Echinococcus granulosus tm gpcr rhodopsin 0.0174 0.0421 0.041
Echinococcus granulosus g protein coupled receptor 0.0174 0.0421 0.041
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0174 0.0421 0.041
Mycobacterium ulcerans Type I modular polyketide synthase 0.0157 0.0378 0.5142
Schistosoma mansoni neuropeptide receptor 0.0174 0.0421 0.041
Mycobacterium ulcerans hypothetical protein 0.0291 0.0724 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0174 0.0421 0.041
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0174 0.0421 0.041
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0022 0.0011
Echinococcus granulosus neuropeptide Y receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0081 0.0178 0.2349
Brugia malayi acetyltransferase, GNAT family protein 0.0172 0.0416 0.0694
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.008 0.0069
Schistosoma mansoni hypothetical protein 0.0174 0.0421 0.041
Mycobacterium leprae conserved hypothetical protein 0.0291 0.0724 1
Brugia malayi beta-lactamase family protein 0.0291 0.0724 0.1208
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0023 0.003 0.0039
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0174 0.0421 0.0702
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0174 0.0421 0.041
Echinococcus granulosus biogenic amine 5HT receptor 0.0174 0.0421 0.041
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0033 0.0312
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0033 0.0312
Trichomonas vaginalis esterase, putative 0.0291 0.0724 0.5849
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0134 0.0223
Echinococcus multilocularis G-protein coupled receptor, putative 0.0174 0.0421 0.041
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0468 0.1183 0.1974
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0174 0.0421 0.041
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0024 0.0013
Mycobacterium tuberculosis Probable lipase LipD 0.0291 0.0724 0.1492
Brugia malayi AKH receptor 0.0174 0.0421 0.0702
Echinococcus granulosus synaptojanin 1 0.0027 0.004 0.0029
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0033 0.0056
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0468 0.1183 0.1173
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Giardia lamblia Methyltransferase like 2 0.0047 0.0093 0.2337
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0174 0.0421 0.041
Echinococcus granulosus expressed protein 0.002 0.0022 0.0011
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0056 0.1735
Brugia malayi hypothetical protein 0.0016 0.0011 0.0019
Schistosoma mansoni neuropeptide receptor 0.0174 0.0421 0.041
Echinococcus granulosus histone acetyltransferase KAT2B 0.0167 0.0403 0.0393
Echinococcus multilocularis neuropeptides capa receptor 0.0174 0.0421 0.041
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0043 0.0451
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0174 0.0421 0.041
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0174 0.0421 0.041
Brugia malayi UDP-GlcNAc:a-6-D-mannoside b1,2-N-acetylglucosaminyltransferase II 0.2323 0.5992 1
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0027 0.004 0.041
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0167 0.0403 0.5498
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0285 0.0475
Loa Loa (eye worm) hypothetical protein 0.0061 0.0129 0.0215
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0291 0.0724 0.1492
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Mycobacterium ulcerans thioesterase TesA 0.0131 0.031 0.4189
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0033 0.0312
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.004
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0174 0.0421 0.041
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0468 0.1183 0.1173
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0174 0.0421 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Schistosoma mansoni cript-related 0.0027 0.004 0.0029
Echinococcus multilocularis g protein coupled receptor 0.0174 0.0421 0.041
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0039 0.0072 0.0061
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0127 0.0298 0.4025
Plasmodium falciparum acyl carrier protein 0.0016 0.0011 0.0337
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0174 0.0421 0.0702
Trypanosoma brucei hypothetical protein, conserved 0.0236 0.0581 0.7998
Schistosoma mansoni neuropeptide F-like receptor 0.0174 0.0421 0.041
Entamoeba histolytica hypothetical protein 0.0023 0.0029 0.0514
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0254 0.0629 0.105
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.0724 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0056 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0127 0.0298 0.4025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0291 0.0724 0.0714
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0129 0.0118
Onchocerca volvulus 0.0061 0.0129 0.0975
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0027 0.004 0.0029
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0167 0.0403 0.0821
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.004 0.0873
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0014 0.0005
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0027 0.004 0.0153
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0154 0.0369 0.0617
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0135 0.0319 0.4314
Mycobacterium tuberculosis Probable lipase LipE 0.0291 0.0724 0.1492
Schistosoma mansoni ran 0.0021 0.0024 0.0013
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.009 0.2822
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0028 0.0042 0.007
Plasmodium vivax importin-beta 2, putative 0.0028 0.0043 0.0592
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0023 0.003 0.0261
Echinococcus multilocularis peregrin 0.0035 0.006 0.0049
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0039 0.0072 0.0858
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0017 0.0014 0.0036
Schistosoma mansoni hypothetical protein 0.0027 0.004 0.0029
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0039 0.0072 0.0858
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0056 0.0624
Schistosoma mansoni methyltransferase-related 0.0047 0.0093 0.0082
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0027 0.004 0.0029
Onchocerca volvulus 0.0027 0.004 0.0241
Brugia malayi larval opioid receptor 0.0174 0.0421 0.0702
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0022 0.0037
Trichomonas vaginalis ran, putative 0.0021 0.0024 0.0015
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0039 0.0072 0.0858
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.009 0.225
Echinococcus granulosus sex peptide receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0031 0.0049 0.0082
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.002 0.0022 0.0037
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0022 0.0011
Onchocerca volvulus 0.0154 0.0369 0.296
Brugia malayi Phosphopantetheine attachment site family protein 0.0016 0.0011 0.0018
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0049 0.0535
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0157 0.0378 0.0768
Plasmodium vivax acyl carrier protein, putative 0.0016 0.0011 0.0148
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0027 0.004 0.0153
Mycobacterium ulcerans Type I modular polyketide synthase 0.0157 0.0378 0.5142
Brugia malayi G-protein coupled receptor 0.0174 0.0421 0.0702
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0174 0.0421 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Mycobacterium ulcerans hypothetical protein 0.0027 0.004 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0054

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.