Detailed information for compound 1624743

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 340.396 | Formula: C18H16N2O3S
  • H donors: 1 H acceptors: 1 LogP: 3.98 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(ccc1OC)C=C1SC(=Nc2ccccc2)NC1=O
  • InChi: 1S/C18H16N2O3S/c1-22-14-9-8-12(10-15(14)23-2)11-16-17(21)20-18(24-16)19-13-6-4-3-5-7-13/h3-11H,1-2H3,(H,19,20,21)
  • InChiKey: YCLBAPJEFDBZNN-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens NIMA-related kinase 2 Starlite/ChEMBL No references
Homo sapiens cyclin-dependent kinase 5 Starlite/ChEMBL No references
Homo sapiens Pim-1 proto-oncogene, serine/threonine kinase Starlite/ChEMBL No references
Homo sapiens MAP kinase interacting serine/threonine kinase 2 Starlite/ChEMBL No references
Homo sapiens TAO kinase 1 Starlite/ChEMBL No references
Homo sapiens LIM domain kinase 1 Starlite/ChEMBL No references
Homo sapiens Rho-associated, coiled-coil containing protein kinase 1 Starlite/ChEMBL No references
Homo sapiens doublecortin-like kinase 2 Starlite/ChEMBL No references
Homo sapiens STE20-like kinase Starlite/ChEMBL No references
Homo sapiens Pim-3 proto-oncogene, serine/threonine kinase Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase kinase kinase kinase 5 Starlite/ChEMBL No references
Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 1 Starlite/ChEMBL No references
Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase-activated protein kinase 3 Starlite/ChEMBL No references
Homo sapiens serum/glucocorticoid regulated kinase 2 Starlite/ChEMBL No references
Homo sapiens protein kinase D3 Starlite/ChEMBL No references
Homo sapiens interleukin-1 receptor-associated kinase 4 Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase kinase kinase kinase 4 Starlite/ChEMBL No references
Homo sapiens BR serine/threonine kinase 1 Starlite/ChEMBL No references
Homo sapiens v-akt murine thymoma viral oncogene homolog 3 Starlite/ChEMBL No references
Homo sapiens CDC42 binding protein kinase alpha (DMPK-like) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus serine threonine protein kinase nrc Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129617 All targets in OG5_129617
Trypanosoma brucei gambiense serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase Get druggable targets OG5_131483 All targets in OG5_131483
Schistosoma japonicum ko:K07117 SET and MYND domain containing 1a, putative Get druggable targets OG5_129617 All targets in OG5_129617
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative Get druggable targets OG5_129446 All targets in OG5_129446
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans likely signal transduction kinase Get druggable targets OG5_127124 All targets in OG5_127124
Candida albicans likely protein kinase similar to S. cerevisiae YPK2 (YMR104C) Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_131020 All targets in OG5_131020
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129521 All targets in OG5_129521
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase Get druggable targets OG5_131020 All targets in OG5_131020
Brugia malayi Phorbol esters/diacylglycerol binding domain Get druggable targets OG5_130080 All targets in OG5_130080
Leishmania braziliensis protein kinase, putative,SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium vivax serine/threonine protein kinase KIN, putative Get druggable targets OG5_126655 All targets in OG5_126655
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_131483 All targets in OG5_131483
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130670 All targets in OG5_130670
Schistosoma japonicum Serine/threonine-protein kinase minibrain, putative Get druggable targets OG5_127901 All targets in OG5_127901
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania donovani 5'-AMP-activated protein kinase catalytic subunit alpha, putative Get druggable targets OG5_126655 All targets in OG5_126655
Toxoplasma gondii NIMA-related protein kinase NIMA1 Get druggable targets OG5_129446 All targets in OG5_129446
Plasmodium yoelii NIMA-related protein kinase Get druggable targets OG5_129446 All targets in OG5_129446
Echinococcus granulosus 5' AMP activated protein kinase catalytic Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum IPR000437,Prokaryotic membrane lipoprotein lipid attachment site,domain-containing Get druggable targets OG5_128641 All targets in OG5_128641
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K07198 5'-AMP-activated protein kinase, catalytic alpha subunit, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative Get druggable targets OG5_127124 All targets in OG5_127124
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127124 All targets in OG5_127124
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum expressed protein Get druggable targets OG5_127901 All targets in OG5_127901
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Brugia malayi Serine/threonine-protein kinase Pim-3 Get druggable targets OG5_134863 All targets in OG5_134863
Echinococcus multilocularis Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis serine:threonine protein kinase TAO1 Get druggable targets OG5_129521 All targets in OG5_129521
Brugia malayi Doublecortin family protein Get druggable targets OG5_131156 All targets in OG5_131156
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129617 All targets in OG5_129617
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase Get druggable targets OG5_131958 All targets in OG5_131958
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum MAP/microtubule affinity-regulating kinase 4, putative Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative Get druggable targets OG5_126655 All targets in OG5_126655
Brugia malayi probable protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus multilocularis Get druggable targets OG5_128641 All targets in OG5_128641
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Plasmodium yoelii kinase Akt/PKB-related Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei gambiense rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus multilocularis serine:threonine protein kinase PAK 3 Get druggable targets OG5_127124 All targets in OG5_127124
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K08837 serine/threonine kinase 10, putative Get druggable targets OG5_130670 All targets in OG5_130670
Echinococcus granulosus serine:threonine protein kinase PAK 3 Get druggable targets OG5_127124 All targets in OG5_127124
Loa Loa (eye worm) CAMK/PIM protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum Serine/threonine-protein kinase pak-1, putative Get druggable targets OG5_127124 All targets in OG5_127124
Schistosoma japonicum Mitogen-activated protein kinase kinase kinase kinase 4, putative Get druggable targets OG5_128641 All targets in OG5_128641
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus serine:threonine protein kinase TAO1 Get druggable targets OG5_129521 All targets in OG5_129521
Plasmodium vivax rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126635 All targets in OG5_126635
Neospora caninum hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum Serine/threonine-protein kinase PAK 3, putative Get druggable targets OG5_127124 All targets in OG5_127124
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K04429 thousand and one amino acid protein kinase, putative Get druggable targets OG5_129521 All targets in OG5_129521
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan Get druggable targets OG5_129617 All targets in OG5_129617
Schistosoma japonicum expressed protein Get druggable targets OG5_130080 All targets in OG5_130080
Brugia malayi p70 ribosomal S6 kinase beta Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum IPR002219,Protein kinase C, phorbol ester/diacylglycerol binding,domain-containing Get druggable targets OG5_131020 All targets in OG5_131020
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_129446 All targets in OG5_129446
Echinococcus multilocularis serine:threonine protein kinase MRCK beta Get druggable targets OG5_129617 All targets in OG5_129617
Leishmania infantum serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi Protein kinase domain Get druggable targets OG5_127124 All targets in OG5_127124
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus serine:threonine protein kinase PAK 3 Get druggable targets OG5_127124 All targets in OG5_127124
Leishmania mexicana serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase Get druggable targets OG5_129617 All targets in OG5_129617
Schistosoma japonicum Serine/threonine-protein kinase mig-15, putative Get druggable targets OG5_128641 All targets in OG5_128641
Brugia malayi C1-like domain containing protein Get druggable targets OG5_130080 All targets in OG5_130080
Schistosoma japonicum ko:K05743 LIM domain kinase 1, putative Get druggable targets OG5_131191 All targets in OG5_131191
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127124 All targets in OG5_127124
Toxoplasma gondii histone kinase SNF1, putative Get druggable targets OG5_126655 All targets in OG5_126655
Giardia lamblia Kinase, NEK Get druggable targets OG5_129446 All targets in OG5_129446
Echinococcus granulosus serine:threonine protein kinase PAK 1 Get druggable targets OG5_127124 All targets in OG5_127124
Schistosoma japonicum IPR000719,Protein kinase;IPR011009,Protein kinase-like,domain-containing Get druggable targets OG5_127124 All targets in OG5_127124
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi hypothetical protein Get druggable targets OG5_129521 All targets in OG5_129521
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans protein serine/threonine kinase Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128641 All targets in OG5_128641
Schistosoma mansoni protein kinase Get druggable targets OG5_129692 All targets in OG5_129692
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus MAP kinase activated protein kinase 2 Get druggable targets OG5_131483 All targets in OG5_131483
Candida albicans likely protein kinase similar to S. cerevisiae KIN3 (YAR018C) Get druggable targets OG5_129446 All targets in OG5_129446
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis proto oncogene serine:threonine protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Trypanosoma brucei CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Loa Loa (eye worm) CAMK/PKD protein kinase Get druggable targets OG5_130080 All targets in OG5_130080
Loa Loa (eye worm) STE/STE20/KHS protein kinase Get druggable targets OG5_129692 All targets in OG5_129692
Schistosoma japonicum ko:K04409 p21-activated kinase 1, putative Get druggable targets OG5_127124 All targets in OG5_127124
Schistosoma japonicum ko:K08282 non-specific serine/threonine protein kinase [EC2.7.11.1], putative Get druggable targets OG5_129617 All targets in OG5_129617
Schistosoma mansoni protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Candida albicans similar to S. cerevisiae HSL1 (YKL101W) serine/threonine-protein kinase involved in cell cycle control Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus mitogen activated protein kinase kinase kinase Get druggable targets OG5_129692 All targets in OG5_129692
Candida albicans serine-threonine kinase Get druggable targets OG5_127124 All targets in OG5_127124
Schistosoma japonicum ko:K06070 protein kinase D, putative Get druggable targets OG5_130080 All targets in OG5_130080
Neospora caninum Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1), related Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis 5' AMP activated protein kinase catalytic Get druggable targets OG5_126655 All targets in OG5_126655
Plasmodium falciparum serine/threonine protein kinase KIN Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma mansoni protein kinase Get druggable targets OG5_131191 All targets in OG5_131191
Echinococcus granulosus Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus serine:threonine protein kinase mig 15 Get druggable targets OG5_128641 All targets in OG5_128641
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127124 All targets in OG5_127124
Cryptosporidium hominis NEK2 protein Get druggable targets OG5_129446 All targets in OG5_129446
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 Get druggable targets OG5_127124 All targets in OG5_127124
Trypanosoma cruzi Protein kinase B Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum IPR001180,Citron-like,domain-containing Get druggable targets OG5_129692 All targets in OG5_129692
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis dual specificity testis specific protein kinase Get druggable targets OG5_131191 All targets in OG5_131191
Schistosoma japonicum Serine/threonine-protein kinase PAK 3, putative Get druggable targets OG5_127124 All targets in OG5_127124
Giardia lamblia Kinase, CAMK CAMKL Get druggable targets OG5_126655 All targets in OG5_126655
Giardia lamblia Kinase, CAMK CAMKL Get druggable targets OG5_126655 All targets in OG5_126655
Theileria parva NIMA-related protein kinase, putative Get druggable targets OG5_129446 All targets in OG5_129446
Schistosoma japonicum Serine/threonine-protein kinase STE20, putative Get druggable targets OG5_127124 All targets in OG5_127124
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni protein kinase Get druggable targets OG5_131191 All targets in OG5_131191
Schistosoma japonicum expressed protein Get druggable targets OG5_129617 All targets in OG5_129617
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_131020 All targets in OG5_131020
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans serine-threonine kinase Get druggable targets OG5_127124 All targets in OG5_127124
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus rho-associated protein kinase 1 Get druggable targets OG5_131020 All targets in OG5_131020
Schistosoma japonicum ko:K08796 BR serine/threonine kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans bud neck kinase Get druggable targets OG5_126655 All targets in OG5_126655
Plasmodium knowlesi RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei gambiense protein kinase, putative,SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 Get druggable targets OG5_127124 All targets in OG5_127124
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum HD domain-containing protein 2 homolog, putative Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Onchocerca volvulus Get druggable targets OG5_130080 All targets in OG5_130080
Brugia malayi map kinase activated protein kinase protein 2 Get druggable targets OG5_131483 All targets in OG5_131483
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania donovani serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K08282 non-specific serine/threonine protein kinase [EC2.7.11.1], putative Get druggable targets OG5_128641 All targets in OG5_128641
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) STE/STE20/PAKA protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum expressed protein Get druggable targets OG5_130670 All targets in OG5_130670
Schistosoma japonicum ko:K04443 mitogen-activated protein kinase-activated protein kinase 2, putative Get druggable targets OG5_131483 All targets in OG5_131483
Echinococcus multilocularis rac serine:threonine kinase Get druggable targets OG5_126635 All targets in OG5_126635
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis rho associated protein kinase Get druggable targets OG5_131020 All targets in OG5_131020
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126655 All targets in OG5_126655
Trypanosoma brucei SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum Sodium/potassium-transporting ATPase subunit beta-1, putative Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) STE/STE20/MSN protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Loa Loa (eye worm) STE/STE20/SLK protein kinase Get druggable targets OG5_130670 All targets in OG5_130670
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative Get druggable targets OG5_127124 All targets in OG5_127124
Echinococcus multilocularis serine:threonine kinase SAD 1 Get druggable targets OG5_126655 All targets in OG5_126655
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium knowlesi serine/threonine protein kinase KIN, putative Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) camk/dcamkl protein kinase Get druggable targets OG5_131156 All targets in OG5_131156
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma congolense rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis STE family protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Trypanosoma cruzi p21-activated kinase 3, putative Get druggable targets OG5_127124 All targets in OG5_127124
Schistosoma japonicum ko:K04702 proto-oncogene serine/threonine-protein kinase Pim-1, putative Get druggable targets OG5_134863 All targets in OG5_134863
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma japonicum Mitogen-activated protein kinase kinase kinase kinase 3, putative Get druggable targets OG5_129692 All targets in OG5_129692
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania braziliensis serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_130670 All targets in OG5_130670
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica p21-activated kinase Get druggable targets OG5_127124 All targets in OG5_127124
Leishmania infantum protein kinase, putative,SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_129692 All targets in OG5_129692
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania donovani SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum ko:K07390 monothiol glutaredoxin, putative Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum MGC81305 protein, related Get druggable targets OG5_129446 All targets in OG5_129446
Loa Loa (eye worm) CAMK/PKD protein kinase Get druggable targets OG5_130080 All targets in OG5_130080
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni protein kinase C mu Get druggable targets OG5_130080 All targets in OG5_130080
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) AGC/RSK/P70 protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium falciparum NIMA related kinase 1 Get druggable targets OG5_129446 All targets in OG5_129446
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Onchocerca volvulus Get druggable targets OG5_130080 All targets in OG5_130080
Schistosoma japonicum Serine/threonine-protein kinase mig-15, putative Get druggable targets OG5_128641 All targets in OG5_128641
Schistosoma mansoni protein kinase Get druggable targets OG5_130670 All targets in OG5_130670
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum ko:K08792 serum/glucocorticoid regulated kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Theileria parva 5'-AMP-activated protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129692 All targets in OG5_129692
Plasmodium berghei NIMA related kinase 1, putative Get druggable targets OG5_129446 All targets in OG5_129446
Plasmodium berghei rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus proto oncogene serine:threonine protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_134863 All targets in OG5_134863
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum ko:K06070 protein kinase D, putative Get druggable targets OG5_130080 All targets in OG5_130080
Candida albicans similar to S. cerevisiae HSL1 (YKL101W) serine/threonine-protein kinase involved in cell cycle control Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum ko:K04456 RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Toxoplasma gondii AGC kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus calcium:calmodulin dependent protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus multilocularis serine:threonine protein kinase PAK 3 Get druggable targets OG5_127124 All targets in OG5_127124
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Candida albicans protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus dual specificity testis-specific protein kinase Get druggable targets OG5_131191 All targets in OG5_131191
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma japonicum expressed protein Get druggable targets OG5_129617 All targets in OG5_129617
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Onchocerca volvulus Get druggable targets OG5_131020 All targets in OG5_131020
Onchocerca volvulus Get druggable targets OG5_130080 All targets in OG5_130080
Giardia lamblia Kinase, STE STE20 Get druggable targets OG5_127124 All targets in OG5_127124
Schistosoma japonicum RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus serine:threonine kinase SAD 1 Get druggable targets OG5_126655 All targets in OG5_126655
Onchocerca volvulus Serine\/threonine protein kinase homolog Get druggable targets OG5_134863 All targets in OG5_134863
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis STE family protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CAMK/PIM protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Echinococcus multilocularis MAP kinase activated protein kinase 2 Get druggable targets OG5_131483 All targets in OG5_131483
Candida albicans bud neck kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum IPR000095,PAK-box/P21-Rho-binding;IPR011026,Wiscott-Aldrich syndrome, C-terminal,domain-containing Get druggable targets OG5_127124 All targets in OG5_127124
Schistosoma mansoni protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Trypanosoma congolense SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Giardia lamblia Kinase, NEK Get druggable targets OG5_129446 All targets in OG5_129446
Candida albicans likely signal transduction kinase Get druggable targets OG5_127124 All targets in OG5_127124
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Candida albicans protein serine/threonine kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Entamoeba histolytica protein kinase 2, putative Get druggable targets OG5_126635 All targets in OG5_126635
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K08286 protein-serine/threonine kinase [EC2.7.11.-], putative Get druggable targets OG5_129692 All targets in OG5_129692
Echinococcus multilocularis STE20 serine:threonine protein kinase Get druggable targets OG5_130670 All targets in OG5_130670
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) AGC/AKT protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Giardia lamblia Kinase, NEK Get druggable targets OG5_129446 All targets in OG5_129446
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis STE family protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Cryptosporidium parvum OSK4, putative Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus STE20 serine:threonine protein kinase Get druggable targets OG5_130670 All targets in OG5_130670
Loa Loa (eye worm) STE/STE20/TAO protein kinase Get druggable targets OG5_129521 All targets in OG5_129521
Loa Loa (eye worm) STE/STE20/PAKA protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Cryptosporidium parvum NEK2 protein, putative Get druggable targets OG5_129446 All targets in OG5_129446
Echinococcus multilocularis mitogen activated protein kinase kinase kinase Get druggable targets OG5_129692 All targets in OG5_129692
Brugia malayi putative serine/threonine kinase SADA gamma Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans likely protein kinase similar to S. cerevisiae KIN3 (YAR018C) Get druggable targets OG5_129446 All targets in OG5_129446
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative Get druggable targets OG5_126655 All targets in OG5_126655
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis STE family protein kinase Get druggable targets OG5_129446 All targets in OG5_129446
Leishmania infantum serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_129446 All targets in OG5_129446
Schistosoma japonicum Rho-associated protein kinase 1, putative Get druggable targets OG5_131020 All targets in OG5_131020
Trichomonas vaginalis STE family protein kinase Get druggable targets OG5_127124 All targets in OG5_127124
Brugia malayi Serine/threonine-protein kinase SULU Get druggable targets OG5_129521 All targets in OG5_129521
Schistosoma japonicum hypothetical protein Get druggable targets OG5_129692 All targets in OG5_129692
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Onchocerca volvulus Get druggable targets OG5_131020 All targets in OG5_131020
Schistosoma mansoni protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Brugia malayi p21/Cdc42/Rac1-activated kinase Get druggable targets OG5_127124 All targets in OG5_127124
Plasmodium knowlesi NIMA related kinase 1, putative Get druggable targets OG5_129446 All targets in OG5_129446
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_131958 All targets in OG5_131958
Giardia lamblia Kinase, AGC PKA Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum Serine/threonine-protein kinase PAK 1, putative Get druggable targets OG5_127124 All targets in OG5_127124
Trypanosoma cruzi SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi casein kinase II, alpha chain, putative mitogen-activated protein kinase-activated protein kinase 3 382 aa 312 aa 26.0 %
Giardia lamblia Kinase, NEK NIMA-related kinase 2 388 aa 312 aa 25.0 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 5 260 aa 307 aa 28.3 %
Trypanosoma brucei protein lipid droplet kinase (LDK) Pim-3 proto-oncogene, serine/threonine kinase 326 aa 296 aa 29.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Kinase, CMGC CDK 0.006 0.0441 0.1307
Brugia malayi Temporarily assigned gene name protein 59 0.0074 0.0702 0.0641
Trypanosoma cruzi cdc2-related kinase 1 0.006 0.0441 0.1634
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.006 0.0441 0.0374
Echinococcus multilocularis nervana 2 0.0058 0.0401 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0431 0.0413
Echinococcus granulosus protein kinase c epsilon type 0.0059 0.0431 0.0277
Trypanosoma brucei cdc2-related kinase 1 0.006 0.0441 0.1634
Trichomonas vaginalis AGC family protein kinase 0.0108 0.1351 0.7433
Onchocerca volvulus 0.0074 0.0702 0.0003
Echinococcus multilocularis rac serine:threonine kinase 0.0071 0.0654 0.0503
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0049 0.0234 0.0077
Entamoeba histolytica PH domain containing protein kinase, putative 0.0071 0.0654 0.3691
Schistosoma mansoni serine/threonine protein kinase 0.0392 0.6761 1
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.2798 0.3997
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0154 0.224 0.2116
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0074 0.0702 0.3696
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0392 0.6761 0.6709
Entamoeba histolytica protein kinase, putative 0.0108 0.1351 0.889
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0234 0.0115
Brugia malayi map kinase activated protein kinase protein 2 0.0225 0.3586 0.3595
Schistosoma mansoni hypothetical protein 0.0074 0.0702 0.0824
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0441 0.2427
Brugia malayi Hr1 repeat family protein 0.0045 0.0158 0.0084
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0053 0.0314 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.3586 0.5192
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0066 0.0559 0.2052
Echinococcus multilocularis cyclin dependent kinase 1 0.006 0.0441 0.0287
Trichomonas vaginalis STE family protein kinase 0.0053 0.0314 0.1729
Echinococcus granulosus dual specificity 0.0116 0.15 0.1363
Trichomonas vaginalis AGC family protein kinase 0.0108 0.1351 0.7433
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0045 0.0158 0.0084
Brugia malayi Protein kinase domain containing protein 0.02 0.3112 0.3109
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0554 0.9842 1
Loa Loa (eye worm) hypothetical protein 0.0093 0.1068 0.1015
Echinococcus multilocularis cyclin dependent kinase 0.006 0.0441 0.0287
Onchocerca volvulus 0.0175 0.2639 0.3199
Schistosoma mansoni serine/threonine-protein kinase 0.0071 0.0654 0.075
Entamoeba histolytica hypothetical protein 0.0116 0.15 1
Schistosoma mansoni protein kinase 0.008 0.0833 0.1022
Entamoeba histolytica p21-activated kinase 0.0058 0.0409 0.1865
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0082 0.086 0.0713
Echinococcus granulosus nervana 2 0.0058 0.0401 0.0246
Loa Loa (eye worm) AGC/PKN protein kinase 0.0045 0.0158 0.0084
Schistosoma mansoni protein kinase 0.0154 0.2233 0.3142
Brugia malayi Protein kinase domain containing protein 0.0045 0.0158 0.0084
Echinococcus granulosus Glutaredoxin protein 5 0.0058 0.0401 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0234 0.0115
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0053 0.0314 0.0159
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0215 0.3396 0.34
Echinococcus granulosus Vam6:Vps39 protein 0.0074 0.0702 0.0553
Brugia malayi Protein kinase domain 0.0053 0.0314 0.0244
Echinococcus granulosus serine:threonine kinase SAD 1 0.0049 0.0234 0.0077
Schistosoma mansoni protein kinase 0.02 0.3112 0.4473
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0049 0.0234 0.0162
Brugia malayi Protein kinase domain containing protein 0.006 0.0441 0.0374
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0096 0.1132 0.1081
Trichomonas vaginalis STE family protein kinase 0.0053 0.0314 0.1729
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0074 0.0702 0.0824
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Loa Loa (eye worm) hypothetical protein 0.0074 0.0702 0.0641
Echinococcus granulosus nervana 2 0.0058 0.0401 0.0246
Brugia malayi hypothetical protein 0.0236 0.3783 0.3796
Brugia malayi Doublecortin family protein 0.015 0.2153 0.2127
Brugia malayi protein kinase C II. 0.0059 0.0431 0.0364
Echinococcus multilocularis nervana 2 0.0058 0.0401 0.0246
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Giardia lamblia Kinase, CMGC CDK 0.006 0.0441 0.1307
Brugia malayi Protein kinase domain containing protein 0.0215 0.3396 0.34
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0116 0.15 1
Trichomonas vaginalis AGC family protein kinase 0.0108 0.1351 0.7433
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0156 0.0858
Trypanosoma cruzi cdc2-related kinase 3 0.006 0.0441 0.1634
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.1997 0.2784
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0074 0.0702 0.0553
Schistosoma mansoni protein kinase 0.0053 0.0314 0.0236
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0258 0.4212 0.4235
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0225 0.3586 0.3595
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0053 0.0314 0.0159
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0059 0.0431 0.0277
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0066 0.0559 0.0407
Brugia malayi Protein kinase domain containing protein 0.0507 0.8953 0.909
Entamoeba histolytica PH domain containing protein kinase, putative 0.0071 0.0654 0.3691
Loa Loa (eye worm) hypothetical protein 0.0045 0.0158 0.0084
Brugia malayi Protein kinase domain containing protein 0.0554 0.9842 1
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0082 0.0859 0.0802
Brugia malayi Serine/threonine-protein kinase SULU 0.0236 0.3783 0.3796
Schistosoma mansoni protein kinase 0.0199 0.3085 0.4433
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0225 0.3586 0.3483
Brugia malayi Temporarily assigned gene name protein 59 0.0155 0.2249 0.2225
Entamoeba histolytica protein kinase, putative 0.0103 0.1257 0.8187
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0059 0.0431 0.0364
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0074 0.0702 0.0824
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0431 0.0413
Echinococcus multilocularis protein kinase c epsilon type 0.0059 0.0431 0.0277
Giardia lamblia Kinase, NEK 0.0132 0.1818 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.1342 0.1296
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0154 0.224 0.2116
Schistosoma mansoni vam6/vps39 related 0.0074 0.0702 0.0824
Trichomonas vaginalis AGC family protein kinase 0.0108 0.1351 0.7433
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0441 0.2427
Brugia malayi Protein kinase domain containing protein 0.0108 0.1351 0.1306
Trichomonas vaginalis AGC family protein kinase 0.0045 0.0158 0.0871
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.008 0.0833 0.0776
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0199 0.3085 0.2974
Plasmodium falciparum protein kinase 5 0.006 0.0441 0.1307
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0441 0.2427
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0441 0.0428
Trypanosoma cruzi cdc2-related kinase 1 0.006 0.0441 0.1634
Loa Loa (eye worm) AGC/NDR protein kinase 0.0045 0.0158 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.224 0.3153
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0236 0.3783 0.3683
Giardia lamblia Kinase, STE STE20 0.0053 0.0314 0.0506
Trichomonas vaginalis AGC family protein kinase 0.0108 0.1351 0.7433
Echinococcus granulosus cyclin dependent kinase 0.006 0.0441 0.0287
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0392 0.6761 0.6845
Loa Loa (eye worm) AGC/AKT protein kinase 0.0108 0.1351 0.1306
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0049 0.0234 0.0162
Brugia malayi Protein kinase domain containing protein 0.0116 0.15 0.1458
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.006 0.0441 0.1634
Echinococcus granulosus protein kinase 0.008 0.0833 0.0686
Trichomonas vaginalis STE family protein kinase 0.0053 0.0314 0.1729
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0116 0.15 0.1458
Echinococcus multilocularis 0.008 0.0833 0.0686
Trypanosoma cruzi Protein kinase B 0.0071 0.0654 0.3312
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0045 0.0158 0.0084
Echinococcus granulosus cyclin dependent kinase 1 0.006 0.0441 0.0287
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0074 0.0702 0.3696
Schistosoma mansoni protein kinase 0.0053 0.0314 0.0236
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0236 0.3783 0.3683
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.006 0.0441 0.0374
Loa Loa (eye worm) hypothetical protein 0.0074 0.0702 0.0641
Giardia lamblia Kinase, NEK 0.0132 0.1818 1
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0392 0.6761 0.6845
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0199 0.3085 0.2974
Schistosoma mansoni protein kinase 0.0199 0.3085 0.4433
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0053 0.0314 0.0159
Onchocerca volvulus 0.0088 0.0973 0.045
Entamoeba histolytica protein kinase, putative 0.0108 0.1351 0.889
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Brugia malayi cell division control protein 2 homolog 0.006 0.0441 0.0374
Trichomonas vaginalis AGC family protein kinase 0.0132 0.1818 1
Brugia malayi Protein kinase domain containing protein 0.0045 0.0158 0.0084
Toxoplasma gondii AGC kinase 0.0103 0.1257 0.6458
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.224 0.3153
Loa Loa (eye worm) hypothetical protein 0.0049 0.0234 0.0162
Echinococcus granulosus serine threonine protein kinase nrc 0.0066 0.0559 0.0407
Trichomonas vaginalis STE family protein kinase 0.0132 0.1818 1
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0225 0.3586 0.3483
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0074 0.0702 0.3696
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0392 0.6761 1
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.006 0.0441 0.1634
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Plasmodium falciparum NIMA related kinase 1 0.0132 0.1818 1
Schistosoma mansoni serine/threonine-protein kinase 0.0071 0.0654 0.075
Echinococcus multilocularis cyclin dependent kinase 5 0.006 0.0441 0.0287
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.006 0.0441 0.1307
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0392 0.6761 0.6709
Echinococcus granulosus serine/threonine protein kinase 0.0071 0.0654 0.0503
Schistosoma mansoni protein kinase C mu 0.0096 0.1132 0.1474
Trypanosoma brucei cdc2-related kinase 3 0.006 0.0441 0.1634
Brugia malayi Protein kinase domain containing protein 0.0392 0.6761 0.6845
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0049 0.0234 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0441 0.0428
Echinococcus granulosus Protein kinase C brain isozyme 0.0059 0.0431 0.0277
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Giardia lamblia Kinase, NEK 0.0132 0.1818 1
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0236 0.3783 0.3796
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0053 0.0314 0.0159
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Schistosoma mansoni atypical protein kinase C 0.0059 0.0431 0.0413
Trichomonas vaginalis AGC family protein kinase 0.0045 0.0158 0.0871
Giardia lamblia Kinase, AGC PKA 0.0066 0.0559 0.2052
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0132 0.1818 1
Entamoeba histolytica cell division protein kinase 2, putative 0.006 0.0441 0.2108
Brugia malayi probable protein kinase 0.0154 0.2233 0.2209
Trypanosoma brucei rac serine-threonine kinase, putative 0.0108 0.1351 0.8823
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0049 0.0234 0.0077
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0116 0.15 1
Trichomonas vaginalis STE family protein kinase 0.0053 0.0314 0.1729
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0103 0.1257 0.1209
Echinococcus multilocularis cyclin dependent kinase 1 0.006 0.0441 0.0287
Schistosoma mansoni protein kinase 0.0215 0.3396 0.4904
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0507 0.8953 0.909
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0116 0.15 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0973 0.0919
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0146 0.2075 0.1947
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0234 0.0115
Echinococcus multilocularis dual specificity 0.0116 0.15 0.1363
Loa Loa (eye worm) hypothetical protein 0.0052 0.0283 0.0212
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0215 0.3396 0.329
Echinococcus granulosus protein kinase c iota type 0.0059 0.0431 0.0277
Schistosoma mansoni rap gtpase-activating protein 0.0074 0.0702 0.0824
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0074 0.0702 0.0553
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0234 0.0115
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0096 0.1132 0.1081
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Entamoeba histolytica protein kinase, putative 0.0116 0.15 1
Entamoeba histolytica protein kinase, putative 0.0116 0.15 1
Brugia malayi Protein kinase domain containing protein 0.0166 0.2451 0.2432
Brugia malayi C1-like domain containing protein 0.0096 0.1132 0.1081
Entamoeba histolytica protein kinase, putative 0.0053 0.0314 0.1163
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0132 0.1818 1
Onchocerca volvulus 0.0093 0.1068 0.0605
Entamoeba histolytica protein kinase domain containing protein 0.0116 0.15 1
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0058 0.0401 0.0246
Loa Loa (eye worm) hypothetical protein 0.0107 0.1342 0.1296
Echinococcus granulosus rho-associated protein kinase 1 0.0184 0.2798 0.2682
Onchocerca volvulus 0.0184 0.2798 0.346
Trichomonas vaginalis AGC family protein kinase 0.0045 0.0158 0.0871
Echinococcus multilocularis protein kinase c iota type 0.0059 0.0431 0.0277
Loa Loa (eye worm) camk/dcamkl protein kinase 0.015 0.2153 0.2127
Brugia malayi putative serine/threonine kinase SADA gamma 0.0049 0.0234 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Brugia malayi p70 ribosomal S6 kinase beta 0.0103 0.1257 0.1209
Plasmodium vivax protein kinase Crk2 0.006 0.0441 0.1307
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.006 0.0441 0.0287
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0082 0.086 0.0713
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.15 0.2032
Loa Loa (eye worm) hypothetical protein 0.0146 0.2075 0.2047
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0392 0.6761 0.6845
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.02 0.3112 0.3109
Trichomonas vaginalis AGC family protein kinase 0.005 0.0253 0.139
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0431 0.0413
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0071 0.0654 0.3312
Loa Loa (eye worm) hypothetical protein 0.0074 0.0701 0.064
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0058 0.0401 0.0246
Brugia malayi hypothetical protein 0.0074 0.0702 0.0641
Echinococcus multilocularis rho associated protein kinase 0.0184 0.2798 0.2682
Echinococcus granulosus cyclin dependent kinase 5 0.006 0.0441 0.0287
Trypanosoma cruzi cdc2-related kinase 3 0.006 0.0441 0.1634
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0234 0.0115
Loa Loa (eye worm) hypothetical protein 0.0554 0.9842 1
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0049 0.0234 0.0162
Trichomonas vaginalis AGC family protein kinase 0.0108 0.1351 0.7433
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0562 1 1
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0116 0.15 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0066 0.0559 0.0407
Loa Loa (eye worm) hypothetical protein 0.0045 0.0156 0.0082
Entamoeba histolytica serine/threonine protein kinase, putative 0.0049 0.0234 0.0566
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.006 0.0441 0.0374
Entamoeba histolytica cell division protein kinase 2, putative 0.006 0.0441 0.2108
Loa Loa (eye worm) hypothetical protein 0.0074 0.0702 0.0641
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0066 0.0559 0.2567
Loa Loa (eye worm) hypothetical protein 0.0074 0.0701 0.064
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.3783 0.549
Entamoeba histolytica protein kinase 2, putative 0.0066 0.0559 0.2988
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0066 0.0559 0.2052
Echinococcus multilocularis Glutaredoxin protein 5 0.0058 0.0401 0.0246
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0234 0.1289
Trichomonas vaginalis AGC family protein kinase 0.0108 0.1351 0.7433
Loa Loa (eye worm) hypothetical protein 0.0143 0.202 0.199
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0053 0.0314 0.0159
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0215 0.3396 0.329

Activities

Activity type Activity value Assay description Source Reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: AKT3 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: KIAA1811 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDC42BPA ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: SGK ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: TAO1 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: IRAK4 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDK5 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PRKCN ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PAK1 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MAPKAPK3 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: LIMK1 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: ROCK1 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: SLK ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: DCAMKL1 ChEMBL. No reference
Ki (functional) > 5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: NEK2 ChEMBL. No reference
Ki (functional) = 5.2 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: DYRK1A ChEMBL. No reference
Ki (functional) = 5.2 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MKNK2 ChEMBL. No reference
Ki (functional) = 5.2 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MAP4K5 ChEMBL. No reference
Ki (functional) = 5.4 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MAP4K4 ChEMBL. No reference
Ki (functional) = 5.8 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PIM1 ChEMBL. No reference
Ki (functional) = 6 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PIM3 ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.